ATE206050T1 - Okulares hypotensium - Google Patents

Okulares hypotensium

Info

Publication number: ATE206050T1
Authority: AT; Austria
Prior art keywords: group; alkyl; formula; alkenyl; carboxyl
Prior art date: 1994-03-16

Application number

AT95912428T

Other languages

English (en)

Inventor

Tomihisa Yokoyama

Tsunemichi Hosokawa

Hiroaki Yanagisawa

Original Assignee

Sankyo Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-16

Filing date

1995-03-16

Publication date

2001-10-15

1995-03-16 Application filed by Sankyo Co filed Critical Sankyo Co

2001-10-15 Application granted granted Critical

2001-10-15 Publication of ATE206050T1 publication Critical patent/ATE206050T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Ophthalmology & Optometry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Materials For Medical Uses (AREA)
Steroid Compounds (AREA)

AT95912428T 1994-03-16 1995-03-16 Okulares hypotensium ATE206050T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP4540494		1994-03-16
PCT/JP1995/000444 WO1995024902A1 (fr)	1994-03-16	1995-03-16	Reducteur de tension oculaire

Publications (1)

Publication Number	Publication Date
ATE206050T1 true ATE206050T1 (de)	2001-10-15

Family

ID=12718322

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT95912428T ATE206050T1 (de)	1994-03-16	1995-03-16	Okulares hypotensium
AT01102527T ATE266402T1 (de)	1994-03-16	1995-03-16	Okulares hypotonikum

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT01102527T ATE266402T1 (de)	1994-03-16	1995-03-16	Okulares hypotonikum

Country Status (20)

Country	Link
US (1)	US5925664A (de)
EP (2)	EP0795326B1 (de)
KR (1)	KR100211446B1 (de)
CN (2)	CN1104898C (de)
AT (2)	ATE206050T1 (de)
AU (1)	AU684916B2 (de)
CZ (1)	CZ284395B6 (de)
DE (2)	DE69522955T2 (de)
DK (2)	DK0795326T3 (de)
ES (2)	ES2221872T3 (de)
FI (2)	FI114897B (de)
GR (1)	GR3036989T3 (de)
HK (1)	HK1000551A1 (de)
HU (1)	HUT74734A (de)
MX (1)	MX9604109A (de)
NO (1)	NO311068B1 (de)
NZ (1)	NZ282485A (de)
PT (2)	PT795326E (de)
RU (1)	RU2123847C1 (de)
WO (1)	WO1995024902A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100611543B1 (ko) *	1999-06-11	2006-08-10	상꾜 가부시키가이샤	국소 투여용 안압 저하 조성물
TWI290470B (en) *	1999-12-01	2007-12-01	Sankyo Co	The composition for treating glaucoma
GR20000100281A (el) *	2000-08-17	2002-05-24	Ιωαννης Ματσουκας	Ανταγωνιστες του υποδοχεα της αγγεοτενσινης ιι και συνθετικες μεθοδοι για την θεραπεια της υπερτασης και καρδιοαγγειακων ασθενειων
AU2002218527A1 (en) *	2000-12-05	2002-06-18	Sankyo Company Limited	Ocular tension-lowering compositions for topical administration
CA2522318C (en) *	2003-04-15	2011-09-13	Sankyo Company Limited	Drug for preventing or treating angiogenic eye diseases

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA875052B (en) *	1986-07-11	1989-03-29	Du Pont	Angiotensin ii receptor blocking imidazoles
US5138069A (en) *	1986-07-11	1992-08-11	E. I. Du Pont De Nemours And Company	Angiotensin II receptor blocking imidazoles
CA1334092C (en) *	1986-07-11	1995-01-24	David John Carini	Angiotensin ii receptor blocking imidazoles
US4820843A (en) *	1987-05-22	1989-04-11	E. I. Du Pont De Nemours And Company	Tetrazole intermediates to antihypertensive compounds
CA1338238C (en) *	1988-01-07	1996-04-09	David John Carini	Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
CA2060656A1 (en) *	1989-06-30	1990-12-31	Robert John Ardecky	Substituted imidazoles
WO1991015206A1 (en) *	1990-04-05	1991-10-17	E.I. Du Pont De Nemours And Company	Treatment of glaucoma and ocular hypertension with imidazole angiotensin-ii receptor antagonists
US5196444A (en) *	1990-04-27	1993-03-23	Takeda Chemical Industries, Ltd.	1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
US5126342A (en) *	1990-10-01	1992-06-30	Merck & Co., Inc.	Imidazole angiotensin ii antagonists incorporating acidic functional groups
FI112942B3 (fi) *	1991-02-21	2012-03-13	Daiichi Sankyo Co Ltd	Menetelmä kohonneen verenpaineen hoitoon ja ennaltaehkäisyyn käyttökelpoisten 4'-(1H-imidatsol-1-yylimetyyli)-1,1' -bifenyylijohdannaisten valmistamiseksi
US5616599A (en) *	1991-02-21	1997-04-01	Sankyo Company, Limited	Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
US5219856A (en) *	1992-04-06	1993-06-15	E. I. Du Pont De Nemours And Company	Angiotensin-II receptor blocking, heterocycle substituted imidazoles
DK0573218T3 (da) *	1992-06-02	2001-06-18	Sankyo Co	4-carboxyimidazolderivater som angiotensin-II antagonister og deres terapeutiske anvendelse
US5310929A (en) *	1992-08-06	1994-05-10	E. I. Du Pont De Nemours And Company	Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
RU2109736C1 (ru) *	1992-12-17	1998-04-27	Санкио Компани Лимитед	Производные бифенила и способ их получения
CZ154994A3 (en) *	1993-07-02	1995-09-13	Senju Pharma Co	Visual hypotensive agent
US5889020A (en) *	1994-02-08	1999-03-30	Ciba Vision Corporation	Treatment of normotensive glaucoma with angiotensin II antagonists

1995
- 1995-03-16 ES ES01102527T patent/ES2221872T3/es not_active Expired - Lifetime
- 1995-03-16 DE DE69522955T patent/DE69522955T2/de not_active Expired - Fee Related
- 1995-03-16 RU RU96121253A patent/RU2123847C1/ru active
- 1995-03-16 HU HU9602534A patent/HUT74734A/hu unknown
- 1995-03-16 KR KR1019960705082A patent/KR100211446B1/ko not_active IP Right Cessation
- 1995-03-16 MX MX9604109A patent/MX9604109A/es not_active IP Right Cessation
- 1995-03-16 CN CN95193132A patent/CN1104898C/zh not_active Expired - Fee Related
- 1995-03-16 ES ES95912428T patent/ES2163501T3/es not_active Expired - Lifetime
- 1995-03-16 AT AT95912428T patent/ATE206050T1/de not_active IP Right Cessation
- 1995-03-16 AT AT01102527T patent/ATE266402T1/de not_active IP Right Cessation
- 1995-03-16 EP EP95912428A patent/EP0795326B1/de not_active Expired - Lifetime
- 1995-03-16 WO PCT/JP1995/000444 patent/WO1995024902A1/ja active IP Right Grant
- 1995-03-16 DE DE69533045T patent/DE69533045T2/de not_active Expired - Fee Related
- 1995-03-16 EP EP01102527A patent/EP1110551B1/de not_active Expired - Lifetime
- 1995-03-16 PT PT95912428T patent/PT795326E/pt unknown
- 1995-03-16 NZ NZ282485A patent/NZ282485A/en not_active IP Right Cessation
- 1995-03-16 CZ CZ962694A patent/CZ284395B6/cs not_active IP Right Cessation
- 1995-03-16 AU AU19602/95A patent/AU684916B2/en not_active Ceased
- 1995-03-16 PT PT01102527T patent/PT1110551E/pt unknown
- 1995-03-16 DK DK95912428T patent/DK0795326T3/da active
- 1995-03-16 DK DK01102527T patent/DK1110551T3/da active
1996
- 1996-09-13 NO NO19963854A patent/NO311068B1/no not_active IP Right Cessation
- 1996-09-16 US US08/725,197 patent/US5925664A/en not_active Expired - Fee Related
- 1996-09-16 FI FI963645A patent/FI114897B/fi active IP Right Grant
1997
- 1997-10-23 HK HK97102015A patent/HK1000551A1/xx not_active IP Right Cessation
2001
- 2001-10-24 GR GR20010401862T patent/GR3036989T3/el not_active IP Right Cessation
2002
- 2002-05-11 CN CNB021199396A patent/CN1202819C/zh not_active Expired - Fee Related
2004
- 2004-09-24 FI FI20041236A patent/FI115197B/fi active IP Right Grant

Also Published As

Publication number	Publication date
AU1960295A (en)	1995-10-03
RU2123847C1 (ru)	1998-12-27
EP0795326A1 (de)	1997-09-17
HU9602534D0 (en)	1996-11-28
CZ269496A3 (en)	1996-12-11
HUT74734A (en)	1997-02-28
NZ282485A (en)	1997-06-24
EP1110551A2 (de)	2001-06-27
ES2163501T3 (es)	2002-02-01
NO963854D0 (no)	1996-09-13
EP0795326B1 (de)	2001-09-26
US5925664A (en)	1999-07-20
MX9604109A (es)	1997-09-30
FI963645A0 (fi)	1996-09-16
CN1387846A (zh)	2003-01-01
DE69522955D1 (de)	2001-10-31
CZ284395B6 (cs)	1998-11-11
PT1110551E (pt)	2004-07-30
CN1104898C (zh)	2003-04-09
GR3036989T3 (en)	2002-01-31
FI115197B (fi)	2005-03-31
HK1000551A1 (en)	2002-04-12
DE69533045D1 (de)	2004-06-17
NO963854L (no)	1996-11-14
DE69533045T2 (de)	2005-01-27
CN1202819C (zh)	2005-05-25
ES2221872T3 (es)	2005-01-16
EP0795326A4 (de)	1997-09-17
KR100211446B1 (ko)	1999-08-02
KR970701542A (ko)	1997-04-12
DK0795326T3 (da)	2001-11-26
EP1110551B1 (de)	2004-05-12
FI114897B (fi)	2005-01-31
NO311068B1 (no)	2001-10-08
DK1110551T3 (da)	2004-06-07
PT795326E (pt)	2002-01-30
AU684916B2 (en)	1998-01-08
FI20041236A (fi)	2004-09-24
EP1110551A3 (de)	2001-08-16
FI963645A (fi)	1996-11-14
DE69522955T2 (de)	2002-05-29
ATE266402T1 (de)	2004-05-15
WO1995024902A1 (fr)	1995-09-21
CN1148809A (zh)	1997-04-30

Publication	Publication Date	Title
ATE194335T1 (de)	2000-07-15	4,5-diaryloxazol-derivate
DK0449216T3 (da)	1996-07-01	3,5-Di-tertiærbutyl-4-hydroxyphenylmethylenderivater af 2-substituerede thiazolidinoner, oxazolidinoner og imidazolidinoner som antiinflammatoriske midler
ATE216584T1 (de)	2002-05-15	Xanthine-derivate als antidepressiva
DE69111816D1 (de)	1995-09-07	Indolederivate und ihre verwendung als serotonin-antagoniste.
ATE227710T1 (de)	2002-11-15	Oxazole derivate,ihre herstellung und verwendung
DK0916651T3 (da)	2003-12-01	Phenylalkylcarboxylsyrederivater
ATE421524T1 (de)	2009-02-15	5-ring-heterocyclen, ihre herstellung, ihre verwendung als inhibitoren der leukozytenadhäsion und sie enthaltende pharmazeutische präparate
ATE206050T1 (de)	2001-10-15	Okulares hypotensium
DK147588D0 (da)	1988-03-17	Benzoxazinderivat samt fremgangsmaade til fremstilling deraf
DE69226931D1 (de)	1998-10-15	Guanidinothiazolederivate und ihre Anwendung als H2-Rezeptor-Antagonisten
NO872874D0 (no)	1987-07-10	Amid-derivater.
NO893039D0 (no)	1989-07-26	Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler.
ATE144900T1 (de)	1996-11-15	Verwendung von xanthinderivaten gegen magengeschwüre
EP0878475A3 (de)	1998-11-25	5-(4-Piperidinyl)dibenzothiazepine derivate und 5-(4-piperidinyl)dibenzoxazepinderivate, und antiarrhythmische Mittel
DE68905222D1 (de)	1993-04-15	7-(1-imidazolyl)-1,4-dihydro-4-oxo-6,8-difluoro-1-cyclopropylchinolincarbonsaeure-derivate, ihre herstellung und ihre verwendung als arzneimittel.
TH18321B (th)	1996-04-25	สารออกฤทธิ์ต้านตัวรับแทคิไคนินชนิดนอนเพปไทด์

Legal Events

Date	Code	Title	Description
2002-02-15	UEP	Publication of translation of european patent specification
2010-12-15	REN	Ceased due to non-payment of the annual fee