ATE201416T1 - Varianten von adhäsionsmoleküle für blutplättchen - Google Patents
Varianten von adhäsionsmoleküle für blutplättchenInfo
- Publication number
- ATE201416T1 ATE201416T1 AT91902327T AT91902327T ATE201416T1 AT E201416 T1 ATE201416 T1 AT E201416T1 AT 91902327 T AT91902327 T AT 91902327T AT 91902327 T AT91902327 T AT 91902327T AT E201416 T1 ATE201416 T1 AT E201416T1
- Authority
- AT
- Austria
- Prior art keywords
- variants
- pecam
- adhesion molecules
- blood plates
- glycoprotein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/466,140 US5264554A (en) | 1990-01-19 | 1990-01-19 | Platelet cell adhesion molecule and variants thereof |
PCT/US1990/007418 WO1991010683A1 (en) | 1990-01-19 | 1990-12-27 | A platelet cell adhesion molecule and variants thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE201416T1 true ATE201416T1 (de) | 2001-06-15 |
Family
ID=23850648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91902327T ATE201416T1 (de) | 1990-01-19 | 1990-12-27 | Varianten von adhäsionsmoleküle für blutplättchen |
Country Status (7)
Country | Link |
---|---|
US (2) | US5264554A (de) |
EP (1) | EP0511263B1 (de) |
JP (2) | JPH03216189A (de) |
AT (1) | ATE201416T1 (de) |
CA (2) | CA2023561A1 (de) |
DE (1) | DE69033735T2 (de) |
WO (1) | WO1991010683A1 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6087331A (en) * | 1990-01-19 | 2000-07-11 | The Blood Center Of Southeastern Wisconsin | Therapeutic use of platelet-endothelial cell adhesion molecule-1 compositions |
US5629287A (en) * | 1991-01-18 | 1997-05-13 | University College London | Depot formulations |
US5610148A (en) * | 1991-01-18 | 1997-03-11 | University College London | Macroscopically oriented cell adhesion protein for wound treatment |
US5629162A (en) * | 1991-06-11 | 1997-05-13 | The Center For Blood Research | Method of identifying agents which modulate ICAM-3 binding to LFA-1 |
US5700658A (en) * | 1992-01-27 | 1997-12-23 | Icos Corporation | ICAM-4 materials and methods |
US6153395A (en) * | 1992-01-27 | 2000-11-28 | Icos Corporation | ICAM-related protein |
US5837822A (en) * | 1992-01-27 | 1998-11-17 | Icos Corporation | Humanized antibodies specific for ICAM related protein |
US5753502A (en) * | 1993-08-05 | 1998-05-19 | Icos Corporation | Neuron-specific ICAM-4 promoter |
US5532127A (en) * | 1992-01-27 | 1996-07-02 | Icos Corporation | Assay for 1-CAM related protein expression |
US5773293A (en) * | 1992-01-27 | 1998-06-30 | Icos Corporation | Anti-ICAM-4 antibodies and hybridomas |
US6100383A (en) * | 1992-01-27 | 2000-08-08 | Icos Corporation | Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions |
US5989843A (en) * | 1992-01-27 | 1999-11-23 | Icos Corporation | Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein |
WO1993014776A1 (en) * | 1992-01-27 | 1993-08-05 | Icos Corporation | Icam-related protein |
US5773218A (en) * | 1992-01-27 | 1998-06-30 | Icos Corporation | Method to identify compounds which modulate ICAM-related protein interactions |
US5852170A (en) * | 1992-01-27 | 1998-12-22 | Icos Corporation | ICAM-4 materials and methods |
US5525487A (en) * | 1992-01-27 | 1996-06-11 | Icos Corporation | DNA encoding I-CAM related protein |
US5702917A (en) * | 1992-01-27 | 1997-12-30 | Icos Corporation | Polynucleotides encoding human ICAM-4 |
US6818743B1 (en) | 1992-01-27 | 2004-11-16 | Icos Corporation | I-CAM related protein |
US6884590B1 (en) | 1994-02-11 | 2005-04-26 | Cedars-Sinai Medical Center | Methods of screening for ulcerative colitis and crohn's disease |
US5681699A (en) * | 1994-02-11 | 1997-10-28 | Cedars-Sinai Medical Center | Methods of diagnosing ulcerative colitis and Crohn's disease |
US5668012A (en) * | 1994-07-05 | 1997-09-16 | The Blood Center Research Foundation, Inc. | Platelet endothelial cell adhesion molecule-1 promoters and uses thereof |
GB2294321A (en) * | 1994-10-19 | 1996-04-24 | Yamanouchi Research Inst | Method of screening for CD31 interaction inhibitors |
AU7161096A (en) * | 1995-09-19 | 1997-04-09 | Texas Biotechnology Corporation | Compositions and methods for inhibiting the binding of pecam |
US6991787B1 (en) * | 1995-12-29 | 2006-01-31 | Alg Company | Methods of preparing bone marrow stromal cells for use in gene therapy |
US6841531B2 (en) * | 1996-09-27 | 2005-01-11 | Genervon Biopharmaceuticals Llc | Methods and use of motoneuronotrophic factors |
US6309877B1 (en) | 1996-09-27 | 2001-10-30 | Km Biotech, Inc. | Polynucleotides encoding motoneuronotrophic factors |
US6960656B1 (en) | 1996-10-25 | 2005-11-01 | Cedars Sinai Medical Center | Nucleic acid encoding DS-CAM proteins and products related thereto |
US6147052A (en) * | 1996-12-05 | 2000-11-14 | Km Biotech, Inc. | Method of differentiating erythrocyte progenitor cells |
US5955443A (en) * | 1998-03-19 | 1999-09-21 | Isis Pharmaceuticals Inc. | Antisense modulation of PECAM-1 |
EP2301947A3 (de) * | 1999-02-26 | 2011-11-23 | Millennium Pharmaceuticals, Inc. | Sekretierte Proteine und Verwendungen dafür |
US7083793B2 (en) | 1999-02-26 | 2006-08-01 | Millennium Pharmaceuticals, Inc. | Tango 243 polypeptides and uses thereof |
US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
WO2006002257A2 (en) * | 2004-06-21 | 2006-01-05 | Johns Hopkins Singapore Pte. Ltd. | Pecam-1-related molecules compositions kit of parts and associated methods of use |
CA2657621A1 (en) | 2006-07-14 | 2008-01-17 | Aviva Biosciences Corporation | Methods and compositions for detecting rare cells from a biological sample |
US8486640B2 (en) | 2007-03-21 | 2013-07-16 | Cedars-Sinai Medical Center | Ileal pouch-anal anastomosis (IPAA) factors in the treatment of inflammatory bowel disease |
WO2010062960A2 (en) | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
WO2010075579A2 (en) | 2008-12-24 | 2010-07-01 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy |
KR102343212B1 (ko) | 2013-03-27 | 2021-12-23 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전 |
EP3022295A4 (de) | 2013-07-19 | 2017-03-01 | Cedars-Sinai Medical Center | Signatur des tl1a (tnfsf15)-signalweges |
CN118773299A (zh) | 2016-03-17 | 2024-10-15 | 西达-赛奈医疗中心 | 通过rnaset2诊断炎性肠病的方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4456082A (en) * | 1981-05-18 | 1984-06-26 | Smith International, Inc. | Expandable rock bit |
IL68733A (en) * | 1982-05-19 | 1989-01-31 | Gist Brocades Nv | Kluyveromyces cells transformed by a dna sequence encoding a polypeptide,expression vectors containing said dna sequence and process for the transformation of kluyveromyces cells by said vector |
FR2532656B2 (fr) * | 1982-06-02 | 1985-10-18 | Elf Bio Rech | Nouveau vecteur de clonage et d'expression, levure et bacterie transformees par ce vecteur |
US4699880A (en) * | 1984-09-25 | 1987-10-13 | Immunomedics, Inc. | Method of producing monoclonal anti-idiotype antibody |
US4808537A (en) * | 1984-10-30 | 1989-02-28 | Phillips Petroleum Company | Methanol inducible genes obtained from pichia and methods of use |
US4855231A (en) * | 1984-10-30 | 1989-08-08 | Phillips Petroleum Company | Regulatory region for heterologous gene expression in yeast |
JPS63152982A (ja) * | 1985-08-20 | 1988-06-25 | Takeda Chem Ind Ltd | 新規dnaおよびその用途 |
US4857467A (en) * | 1986-07-23 | 1989-08-15 | Phillips Petroleum Company | Carbon and energy source markers for transformation of strains of the genes Pichia |
US4704692A (en) * | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
WO1989008114A1 (en) * | 1988-02-25 | 1989-09-08 | The General Hospital Corporation | Rapid immunoselection cloning method |
US5081034A (en) * | 1988-11-14 | 1992-01-14 | Brigham & Women's Hospital | Cloned genes which encode elam-1 |
-
1990
- 1990-01-19 US US07/466,140 patent/US5264554A/en not_active Expired - Lifetime
- 1990-02-13 JP JP2032275A patent/JPH03216189A/ja active Pending
- 1990-08-17 CA CA002023561A patent/CA2023561A1/en not_active Abandoned
- 1990-12-27 CA CA002074072A patent/CA2074072A1/en not_active Abandoned
- 1990-12-27 EP EP91902327A patent/EP0511263B1/de not_active Expired - Lifetime
- 1990-12-27 WO PCT/US1990/007418 patent/WO1991010683A1/en active IP Right Grant
- 1990-12-27 JP JP3502820A patent/JPH05508308A/ja active Pending
- 1990-12-27 AT AT91902327T patent/ATE201416T1/de not_active IP Right Cessation
- 1990-12-27 DE DE69033735T patent/DE69033735T2/de not_active Expired - Fee Related
-
1994
- 1994-11-16 US US08/341,300 patent/US6020188A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2023561A1 (en) | 1991-07-20 |
CA2074072A1 (en) | 1991-07-20 |
AU7154691A (en) | 1991-08-05 |
JPH03216189A (ja) | 1991-09-24 |
AU639300B2 (en) | 1993-07-22 |
DE69033735T2 (de) | 2002-04-18 |
WO1991010683A1 (en) | 1991-07-25 |
US6020188A (en) | 2000-02-01 |
DE69033735D1 (de) | 2001-06-28 |
US5264554A (en) | 1993-11-23 |
EP0511263A1 (de) | 1992-11-04 |
JPH05508308A (ja) | 1993-11-25 |
EP0511263B1 (de) | 2001-05-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |