ATE295423T1 - Phosphodiesterase 8 - Google Patents
Phosphodiesterase 8Info
- Publication number
- ATE295423T1 ATE295423T1 AT98953651T AT98953651T ATE295423T1 AT E295423 T1 ATE295423 T1 AT E295423T1 AT 98953651 T AT98953651 T AT 98953651T AT 98953651 T AT98953651 T AT 98953651T AT E295423 T1 ATE295423 T1 AT E295423T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptides
- polynucleotides
- pde8
- expression constructs
- phosphodiesterase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Cereal-Derived Products (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/951,648 US5932465A (en) | 1997-10-16 | 1997-10-16 | Phosphodiesterase 8A |
PCT/US1998/021956 WO1999019495A1 (en) | 1997-10-16 | 1998-10-16 | Phosphodiesterase 8a |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE295423T1 true ATE295423T1 (de) | 2005-05-15 |
Family
ID=25491965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98953651T ATE295423T1 (de) | 1997-10-16 | 1998-10-16 | Phosphodiesterase 8 |
Country Status (14)
Country | Link |
---|---|
US (4) | US5932465A (de) |
EP (2) | EP1571216A3 (de) |
JP (1) | JP2001512327A (de) |
CN (2) | CN1229499C (de) |
AT (1) | ATE295423T1 (de) |
AU (1) | AU1097499A (de) |
BR (1) | BR9806318A (de) |
CA (1) | CA2275135A1 (de) |
DE (1) | DE69830143T2 (de) |
ES (1) | ES2245485T3 (de) |
IL (3) | IL130287A0 (de) |
NO (1) | NO992916L (de) |
RU (2) | RU2272841C2 (de) |
WO (1) | WO1999019495A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2238283C (en) | 1997-05-30 | 2002-08-20 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions |
US5858694A (en) * | 1997-05-30 | 1999-01-12 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of cancerous lesions |
EP0967284A1 (de) * | 1998-05-28 | 1999-12-29 | Pfizer Limited | Phosphodiesterasen |
US6130053A (en) * | 1999-08-03 | 2000-10-10 | Cell Pathways, Inc. | Method for selecting compounds for inhibition of neoplastic lesions |
GB9922125D0 (en) | 1999-09-17 | 1999-11-17 | Pfizer Ltd | Phosphodiesterase enzymes |
US6673564B2 (en) * | 1999-10-18 | 2004-01-06 | Millennium Pharmaceuticals, Inc. | Methods for using 22045, a human cyclic nucleotide phosphodiesterase |
CN1297049A (zh) * | 1999-11-23 | 2001-05-30 | 上海博容基因开发有限公司 | 一种新的多肽——人环磷酸鸟嘌呤抑制的磷酸二酯酶17和编码这种多肽的多核苷酸 |
US6555547B1 (en) | 2000-02-28 | 2003-04-29 | Cell Pathways, Inc. | Method for treating a patient with neoplasia by treatment with a vinca alkaloid derivative |
US6569638B1 (en) | 2000-03-03 | 2003-05-27 | Cell Pathways, Inc | Method for screening compounds for the treatment of neoplasia |
CN1312381A (zh) * | 2000-03-07 | 2001-09-12 | 上海博德基因开发有限公司 | 一种新的多肽——人环腺苷酸磷酸二脂酶13和编码这种多肽的多核苷酸 |
DE60130565D1 (de) * | 2000-09-12 | 2007-10-31 | Univ Bern | Pde8a und seine verwendung |
JP4999255B2 (ja) * | 2001-07-10 | 2012-08-15 | レイクウッド−アメディックス,インコーポレーテッド | オリゴヌクレオチド含有薬理学的組成物およびその使用 |
AU2003276187A1 (en) * | 2002-11-08 | 2004-06-07 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with human phosphodiesterase 8a (pde8a) |
AU2005223847A1 (en) * | 2004-03-19 | 2005-09-29 | Yale University | Detection, isolation and uses of renalase (Monoamine Oxidase C) |
AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
EP1951291A4 (de) | 2005-11-21 | 2012-04-04 | Univ Yale | Verfahren zur regulierung von renalase (monoaminoxidase c) |
CN101917992A (zh) * | 2007-03-27 | 2010-12-15 | 奥默罗斯公司 | 用于治疗运动障碍的pde7抑制剂的用途 |
KR101778036B1 (ko) * | 2009-05-12 | 2017-09-14 | 코닌클리케 필립스 엔.브이. | 전립선암 마커로서의 포스포디에스테라제 4d7 |
CN103443128B (zh) * | 2011-03-11 | 2017-11-24 | 阿雷克森制药公司 | npp1融合蛋白 |
RU2760943C2 (ru) * | 2011-09-15 | 2021-12-01 | Алексион Фармасьютикалз, Инк. | Гибридные белки NPP1 |
US20150119399A1 (en) | 2012-01-10 | 2015-04-30 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
WO2019067502A1 (en) | 2017-09-27 | 2019-04-04 | Alexion Pharmaceuticals, Inc. | METHODS FOR IMPROVING CARDIOVASCULAR FUNCTION AND TREATING CARDIOVASCULAR DISEASE USING RECOMBINANT ECTO-NUCLEOTIDE PYROPHOSPHATASE / PHOSPHODIESTERASE |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2128227C1 (ru) * | 1989-12-22 | 1999-03-27 | Апплайд Резеч Системз АРС Холдинг Н.В. (NL) (Антильские острова) | Способ активации транскрипционно-молчащего гена |
WO1992020808A1 (en) * | 1991-05-15 | 1992-11-26 | Cell Genesys, Inc. | Genomic modifications with homologous dna targeting |
TW402639B (en) * | 1992-12-03 | 2000-08-21 | Transkaryotic Therapies Inc | Protein production and protein delivery |
US5798246A (en) * | 1996-03-25 | 1998-08-25 | Incyte Pharmaceuticals, Inc. | Cyclic nucleotide phosphodiesterase |
-
1997
- 1997-10-16 US US08/951,648 patent/US5932465A/en not_active Expired - Fee Related
-
1998
- 1998-10-16 IL IL13028798A patent/IL130287A0/xx not_active IP Right Cessation
- 1998-10-16 JP JP52275099A patent/JP2001512327A/ja not_active Withdrawn
- 1998-10-16 CN CNB988025817A patent/CN1229499C/zh not_active Expired - Fee Related
- 1998-10-16 CN CNA2005101137657A patent/CN1800399A/zh active Pending
- 1998-10-16 RU RU99115892/13A patent/RU2272841C2/ru not_active IP Right Cessation
- 1998-10-16 EP EP05009465A patent/EP1571216A3/de not_active Withdrawn
- 1998-10-16 AU AU10974/99A patent/AU1097499A/en not_active Abandoned
- 1998-10-16 US US09/174,437 patent/US6133007A/en not_active Expired - Fee Related
- 1998-10-16 DE DE69830143T patent/DE69830143T2/de not_active Revoked
- 1998-10-16 EP EP98953651A patent/EP0944725B1/de not_active Revoked
- 1998-10-16 CA CA002275135A patent/CA2275135A1/en not_active Abandoned
- 1998-10-16 WO PCT/US1998/021956 patent/WO1999019495A1/en not_active Application Discontinuation
- 1998-10-16 AT AT98953651T patent/ATE295423T1/de not_active IP Right Cessation
- 1998-10-16 BR BR9806318-9A patent/BR9806318A/pt not_active Application Discontinuation
- 1998-10-16 ES ES98953651T patent/ES2245485T3/es not_active Expired - Lifetime
-
1999
- 1999-06-03 IL IL130287A patent/IL130287A/en unknown
- 1999-06-15 NO NO992916A patent/NO992916L/no not_active Application Discontinuation
-
2000
- 2000-10-11 US US09/686,055 patent/US6566087B1/en not_active Expired - Fee Related
-
2003
- 2003-05-19 US US10/440,998 patent/US20030215919A1/en not_active Abandoned
-
2005
- 2005-11-21 RU RU2005136013/13A patent/RU2005136013A/ru unknown
-
2006
- 2006-05-17 IL IL175698A patent/IL175698A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0944725A1 (de) | 1999-09-29 |
RU2005136013A (ru) | 2007-05-27 |
DE69830143T2 (de) | 2006-03-02 |
JP2001512327A (ja) | 2001-08-21 |
IL130287A0 (en) | 2000-06-01 |
NO992916L (no) | 1999-08-06 |
CN1800399A (zh) | 2006-07-12 |
EP1571216A3 (de) | 2006-04-26 |
US6133007A (en) | 2000-10-17 |
CN1248291A (zh) | 2000-03-22 |
RU2272841C2 (ru) | 2006-03-27 |
NO992916D0 (no) | 1999-06-15 |
EP1571216A2 (de) | 2005-09-07 |
US6566087B1 (en) | 2003-05-20 |
EP0944725B1 (de) | 2005-05-11 |
US20030215919A1 (en) | 2003-11-20 |
DE69830143D1 (en) | 2005-06-16 |
ES2245485T3 (es) | 2006-01-01 |
WO1999019495A1 (en) | 1999-04-22 |
AU1097499A (en) | 1999-05-03 |
BR9806318A (pt) | 2000-03-14 |
CA2275135A1 (en) | 1999-04-22 |
IL130287A (en) | 2006-08-20 |
US5932465A (en) | 1999-08-03 |
IL175698A0 (en) | 2008-02-09 |
CN1229499C (zh) | 2005-11-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0944725 Country of ref document: EP |
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RZN | Patent revoked |