ATE107920T1 - Verfahren zur herstellung einer chinolincarbonsäure. - Google Patents
Verfahren zur herstellung einer chinolincarbonsäure.Info
- Publication number
- ATE107920T1 ATE107920T1 AT89116178T AT89116178T ATE107920T1 AT E107920 T1 ATE107920 T1 AT E107920T1 AT 89116178 T AT89116178 T AT 89116178T AT 89116178 T AT89116178 T AT 89116178T AT E107920 T1 ATE107920 T1 AT E107920T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- formula
- chem
- salt
- general formula
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 150000003839 salts Chemical class 0.000 abstract 4
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000035484 reaction time Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/022—Boron compounds without C-boron linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU854695A HU196783B (en) | 1985-12-09 | 1985-12-09 | Process for production of quinoline carbonic acid |
HU469485A HU195801B (en) | 1985-12-09 | 1985-12-09 | Process for producing 1-ethyl-6-fluoro-7-piperazino-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE107920T1 true ATE107920T1 (de) | 1994-07-15 |
Family
ID=26317793
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT87900247T ATE82569T1 (de) | 1985-12-09 | 1986-12-09 | Herstellung von chinolincarbonsaeuren. |
AT89116178T ATE107920T1 (de) | 1985-12-09 | 1986-12-09 | Verfahren zur herstellung einer chinolincarbonsäure. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT87900247T ATE82569T1 (de) | 1985-12-09 | 1986-12-09 | Herstellung von chinolincarbonsaeuren. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4981966A (de) |
EP (2) | EP0249620B1 (de) |
JP (1) | JPH0768219B2 (de) |
KR (1) | KR940008287B1 (de) |
AT (2) | ATE82569T1 (de) |
CA (1) | CA1306750C (de) |
CS (1) | CS264345B2 (de) |
DK (2) | DK412287A (de) |
FI (1) | FI86419C (de) |
NO (1) | NO170154C (de) |
SU (1) | SU1722228A3 (de) |
WO (1) | WO1987003587A1 (de) |
YU (1) | YU45810B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5294712A (en) * | 1985-12-09 | 1994-03-15 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Process for the preparation of quinoline carboxylic acids |
YU46451B (sh) * | 1987-04-08 | 1993-10-20 | Chinoin Gyogyszer Es Vegyeszeti Ter Mekek Gyara Rt. | Postupak za dobivanje mešovitih anhidrida hinolin-karboksilne i borne kiseline |
US5380845A (en) * | 1987-06-24 | 1995-01-10 | Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. | Process for the preparation of quinoline carboxylic acid derivatives |
HU203746B (en) * | 1988-12-22 | 1991-09-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing quinoline-carboxylic acid derivatives |
KR900014383A (ko) * | 1989-03-29 | 1990-10-23 | 원본미기재 | 피롤로퀴놀린 유도체, 이의 제조방법 및 이를 사용한 항균제 |
ES2049636B1 (es) * | 1992-04-15 | 1994-12-16 | Genesis Para La Investigacion | Procedimiento para la preparacion de derivados de acidos quinolincarboxilicos. |
WO1993025545A1 (en) * | 1992-06-09 | 1993-12-23 | Korea Research Institute Of Chemical Technology | Novel quinoline derivatives and processes for preparing the same |
ES2077490B1 (es) * | 1992-11-18 | 1996-10-16 | Marga Investigacion | Esteres trimetilsililicos y solvatos de quelatos de acidos quinolin-3-carboxilicos. preparacion y aplicacion al proceso de quinolonas. |
US5440061A (en) * | 1994-03-29 | 1995-08-08 | The Procter & Gamble Company | Hydrolysis of methyl esters in dimethylsulfoxide for production of fatty acids |
ES2092963B1 (es) * | 1995-04-12 | 1997-12-16 | Sint Quimica Sa | Procedimiento para la preparacion del acido 1-ciclopropil-6-fluoro-1, 4-dihidro-7-(1s,4s)-5-metil-2,5-diazabiciclo(2.2.1) hept-2-il)-4-oxo-3-quinolincarboxilico y sus sales. |
CN113135854A (zh) * | 2021-04-23 | 2021-07-20 | 海南通用三洋药业有限公司 | 甲磺酸培氟沙星的合成方法和应用 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53141286A (en) | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
JPS54138582A (en) | 1978-04-19 | 1979-10-27 | Kyorin Seiyaku Kk | Substituted quinolinecarboxylic acid |
FR2424919B1 (fr) | 1978-05-03 | 1980-10-31 | Kyorin Seiyaku Kk | Acide quinoleinecarboxylique substitue et ses derives et leur utilisation comme agents antibacteriens |
JPS5533453A (en) | 1978-08-31 | 1980-03-08 | Dainippon Pharmaceut Co Ltd | Preventive and remedy for infectious disease of fish |
JPS5533543A (en) | 1978-08-31 | 1980-03-08 | Matsushita Electric Works Ltd | Container for preservation under reduced pressure |
JPS5845426B2 (ja) | 1978-09-29 | 1983-10-08 | 杏林製薬株式会社 | 置換キノリンカルボン酸誘導体 |
JPS5560906A (en) * | 1978-10-31 | 1980-05-08 | Fujitsu Ltd | Luminous flux matching device |
JPS5746986A (en) | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
JPS5762259A (en) | 1980-09-05 | 1982-04-15 | Kyorin Pharmaceut Co Ltd | Preparation of substituted quinolinecarboxylic acid derivative |
JPS5932767B2 (ja) * | 1980-10-27 | 1984-08-10 | 日本電信電話株式会社 | 光フアイバv溝接続器 |
JPS57139711A (en) * | 1981-02-25 | 1982-08-28 | Mitsubishi Rayon Co Ltd | Flat plate optical waveguide |
JPS5829789A (ja) | 1981-08-17 | 1983-02-22 | Dai Ichi Seiyaku Co Ltd | ピリドベンズオキサジン誘導体 |
JPS5843977A (ja) | 1981-09-09 | 1983-03-14 | Dai Ichi Seiyaku Co Ltd | ピリドベンズオキサジン誘導体の製法 |
JPS58184817A (ja) * | 1982-02-26 | 1983-10-28 | Yokogawa Hewlett Packard Ltd | 遅延回路 |
DE3363711D1 (en) * | 1982-03-31 | 1986-07-03 | Sterling Drug Inc | New quinolone compounds and preparation thereof |
JPS5921528A (ja) * | 1982-07-27 | 1984-02-03 | Sankyo Kasei Kk | 二硫化鉄の製造方法 |
JPS5980683A (ja) * | 1982-10-30 | 1984-05-10 | Koei Chem Co Ltd | 6−フルオロ−1,8−ナフチリジン誘導体およびその製造法 |
JPS59122470A (ja) | 1982-12-27 | 1984-07-14 | Dai Ichi Seiyaku Co Ltd | キノリン−3−カルボン酸誘導体の製造法 |
EP0120366B1 (de) * | 1983-03-28 | 1988-11-17 | Polaroid Corporation | Optische Komponente zur Verwendung in optischen Datenübertragungssystemen |
AU553415B2 (en) * | 1983-09-19 | 1986-07-17 | Abbott Japan Co., Ltd. | 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids |
JPS6078986A (ja) | 1983-10-07 | 1985-05-04 | Dai Ichi Seiyaku Co Ltd | オキサジン誘導体の製法 |
HU196415B (en) * | 1985-12-09 | 1988-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing quinoline carboxylic acid boric acid anhydrides |
-
1986
- 1986-12-08 CA CA000524724A patent/CA1306750C/en not_active Expired - Lifetime
- 1986-12-09 KR KR1019870700686A patent/KR940008287B1/ko not_active IP Right Cessation
- 1986-12-09 AT AT87900247T patent/ATE82569T1/de not_active IP Right Cessation
- 1986-12-09 YU YU210686A patent/YU45810B/sh unknown
- 1986-12-09 WO PCT/HU1986/000069 patent/WO1987003587A1/en active IP Right Grant
- 1986-12-09 AT AT89116178T patent/ATE107920T1/de not_active IP Right Cessation
- 1986-12-09 EP EP87900247A patent/EP0249620B1/de not_active Expired - Lifetime
- 1986-12-09 JP JP62500206A patent/JPH0768219B2/ja not_active Expired - Lifetime
- 1986-12-09 CS CS869091A patent/CS264345B2/cs not_active IP Right Cessation
- 1986-12-09 EP EP89116178A patent/EP0351889B1/de not_active Expired - Lifetime
-
1987
- 1987-08-03 NO NO873248A patent/NO170154C/no unknown
- 1987-08-04 FI FI873380A patent/FI86419C/fi not_active IP Right Cessation
- 1987-08-07 DK DK412287A patent/DK412287A/da not_active Application Discontinuation
- 1987-08-07 SU SU874203111A patent/SU1722228A3/ru active
-
1989
- 1989-01-10 US US07/295,439 patent/US4981966A/en not_active Expired - Fee Related
- 1989-11-13 DK DK568389A patent/DK568389D0/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
YU45810B (sh) | 1992-07-20 |
KR940008287B1 (ko) | 1994-09-10 |
FI86419C (fi) | 1992-08-25 |
CS264345B2 (en) | 1989-07-12 |
DK412287D0 (da) | 1987-08-07 |
FI873380A0 (fi) | 1987-08-04 |
CS909186A2 (en) | 1988-07-15 |
DK568389A (da) | 1989-11-13 |
WO1987003587A1 (en) | 1987-06-18 |
JPS63502428A (ja) | 1988-09-14 |
FI86419B (fi) | 1992-05-15 |
CA1306750C (en) | 1992-08-25 |
DK568389D0 (da) | 1989-11-13 |
DK412287A (da) | 1987-08-07 |
US4981966A (en) | 1991-01-01 |
SU1722228A3 (ru) | 1992-03-23 |
EP0351889A1 (de) | 1990-01-24 |
ATE82569T1 (de) | 1992-12-15 |
EP0249620A1 (de) | 1987-12-23 |
NO873248L (no) | 1987-08-03 |
KR880700793A (ko) | 1988-04-12 |
FI873380A (fi) | 1987-08-04 |
EP0351889B1 (de) | 1994-06-29 |
JPH0768219B2 (ja) | 1995-07-26 |
NO873248D0 (no) | 1987-08-03 |
NO170154C (no) | 1992-09-16 |
NO170154B (no) | 1992-06-09 |
EP0249620B1 (de) | 1992-11-19 |
YU210686A (en) | 1987-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |