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AR091936A1 - Hormonas de glicoproteina superagonistas de accion prolongada - Google Patents

Hormonas de glicoproteina superagonistas de accion prolongada

Info

Publication number
AR091936A1
AR091936A1 ARP130102702A ARP130102702A AR091936A1 AR 091936 A1 AR091936 A1 AR 091936A1 AR P130102702 A ARP130102702 A AR P130102702A AR P130102702 A ARP130102702 A AR P130102702A AR 091936 A1 AR091936 A1 AR 091936A1
Authority
AR
Argentina
Prior art keywords
hormones
progonged
glucoprotein
superagonist
action
Prior art date
Application number
ARP130102702A
Other languages
English (en)
Inventor
Szkudlinski Mariusz
D Weintraub Bruce
Original Assignee
Trophogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trophogen Inc filed Critical Trophogen Inc
Publication of AR091936A1 publication Critical patent/AR091936A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Esta proporciona análogos superactivos de hormonas de glicoproteína de acción prolongada que demuestran mayor actividad biológica, tanto in vitro como in vivo en comparación con sus homólogos de tipo salvaje. Los análogos son particularmente útiles para el tratamiento de sujetos que muestran baja expresión del receptor o capacidad pobre de respuesta del receptor, y para el tratamiento de cualquier condición asociada con la actividad de las hormonas de glicoproteína.
ARP130102702A 2012-07-30 2013-07-30 Hormonas de glicoproteina superagonistas de accion prolongada AR091936A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261677331P 2012-07-30 2012-07-30

Publications (1)

Publication Number Publication Date
AR091936A1 true AR091936A1 (es) 2015-03-11

Family

ID=49995487

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130102702A AR091936A1 (es) 2012-07-30 2013-07-30 Hormonas de glicoproteina superagonistas de accion prolongada

Country Status (21)

Country Link
US (5) US9187545B2 (es)
EP (4) EP4012033A1 (es)
JP (1) JP6429774B2 (es)
CN (3) CN112409472A (es)
AR (1) AR091936A1 (es)
AU (2) AU2013296709B2 (es)
BR (1) BR112015001885B1 (es)
CA (2) CA3108181A1 (es)
DK (2) DK2880164T3 (es)
ES (2) ES2727659T3 (es)
HR (1) HRP20190847T1 (es)
HU (1) HUE044016T2 (es)
MX (1) MX360717B (es)
NZ (1) NZ707016A (es)
PL (2) PL3572515T3 (es)
PT (2) PT2880164T (es)
RS (1) RS58881B1 (es)
RU (2) RU2018132561A (es)
UA (1) UA118653C2 (es)
WO (1) WO2014022283A2 (es)
ZA (1) ZA201502778B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112409472A (zh) 2012-07-30 2021-02-26 特洛佛根股份有限公司 糖蛋白激素长效超激动剂
US10457713B2 (en) 2012-07-30 2019-10-29 Trophogen, Inc. Glycoprotein hormone long-acting superagonists
WO2015069777A1 (en) 2013-11-05 2015-05-14 Trophogen Inc. Glycoprotein hormone long-acting superagonists
BR102015032660B1 (pt) 2015-12-28 2019-05-28 Ouro Fino Saúde Animal Participações S.A. PROCESSO DE PRODUÇÃO DE UMA GONADOTROFINA CORIÔNICA EQUINA RECOMBINANTE (reCG): COMPOSIÇÃO VETERINÁRIA E USO

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Also Published As

Publication number Publication date
CN112409472A (zh) 2021-02-26
UA118653C2 (uk) 2019-02-25
CA2880520A1 (en) 2014-02-06
DK3572515T3 (da) 2021-10-11
ZA201502778B (en) 2021-09-29
NZ707016A (en) 2017-08-25
RS58881B1 (sr) 2019-08-30
EP2880164A2 (en) 2015-06-10
HUE044016T2 (hu) 2019-09-30
HRP20190847T1 (hr) 2019-09-06
US9249205B2 (en) 2016-02-02
US20160075751A1 (en) 2016-03-17
RU2018132561A (ru) 2018-11-02
ES2727659T3 (es) 2019-10-17
CN104619846A (zh) 2015-05-13
US9187545B2 (en) 2015-11-17
MX2015001414A (es) 2015-09-23
AU2018203815A1 (en) 2018-06-21
AU2013296709B2 (en) 2018-03-08
CN104619846B (zh) 2020-11-03
PT2880164T (pt) 2019-06-05
EP3572515A1 (en) 2019-11-27
WO2014022283A3 (en) 2014-04-03
JP6429774B2 (ja) 2018-11-28
DK2880164T3 (da) 2019-05-20
RU2015103059A (ru) 2016-09-27
US10766941B2 (en) 2020-09-08
BR112015001885A2 (pt) 2017-11-07
AU2013296709A1 (en) 2015-02-19
EP3572515B1 (en) 2021-07-21
EP2880164A4 (en) 2016-03-09
AU2018203815B2 (en) 2019-12-12
US20230357345A1 (en) 2023-11-09
CA2880520C (en) 2021-02-09
US20210054041A1 (en) 2021-02-25
US20140371146A1 (en) 2014-12-18
EP2880164B1 (en) 2019-04-24
EP3533874A1 (en) 2019-09-04
RU2668174C2 (ru) 2018-09-26
BR112015001885B1 (pt) 2022-08-09
CN112458096A (zh) 2021-03-09
PL3572515T3 (pl) 2022-04-11
PT3572515T (pt) 2021-10-22
MX360717B (es) 2018-11-13
CA3108181A1 (en) 2014-02-06
US20140031530A1 (en) 2014-01-30
EP4012033A1 (en) 2022-06-15
WO2014022283A2 (en) 2014-02-06
PL2880164T3 (pl) 2019-10-31
JP2015524819A (ja) 2015-08-27
ES2894135T3 (es) 2022-02-11

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