OA08501A - Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters. - Google Patents

Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters.

Info

Publication number: OA08501A
Authority: OA; OAPI
Prior art keywords: esters; solvates; hydrates; salts; bicyclic compounds
Prior art date: 1985-07-29

Application number

OA59087A

Other languages

English (en)

Inventor

David John Blythin

Ho-Jane Shue

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-29

Filing date

1987-03-16

Publication date

1988-07-29

1987-03-16 Application filed by Schering Corp filed Critical Schering Corp

1988-07-29 Publication of OA08501A publication Critical patent/OA08501A/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Transplantation (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)
Professional, Industrial, Or Sporting Protective Garments (AREA)
Outer Garments And Coats (AREA)

OA59087A 1985-07-29 1987-03-16 Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters. OA08501A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/760,196 US4684727A (en)	1985-07-29	1985-07-29	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

Publications (1)

Publication Number	Publication Date
OA08501A true OA08501A (en)	1988-07-29

Family

ID=25058394

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA59087A OA08501A (en)	1985-07-29	1987-03-16	Zwitterionic bicyclic compounds and their salts, solvates, hydrates and esters.

Country Status (23)

Country	Link
US (4)	US4684727A (de)
EP (1)	EP0232328B1 (de)
JP (1)	JPH0794455B2 (de)
KR (1)	KR900003490B1 (de)
AT (1)	ATE74756T1 (de)
AU (1)	AU597587B2 (de)
CA (1)	CA1263654A (de)
CZ (1)	CZ413991A3 (de)
DE (1)	DE3684903D1 (de)
DK (1)	DK157787A (de)
FI (1)	FI871345A (de)
HU (1)	HU201550B (de)
IE (1)	IE59298B1 (de)
IL (1)	IL79556A (de)
MX (1)	MX9203320A (de)
MY (1)	MY101970A (de)
NO (1)	NO166862C (de)
NZ (1)	NZ217016A (de)
OA (1)	OA08501A (de)
PH (1)	PH23887A (de)
PT (1)	PT83080B (de)
WO (1)	WO1987000752A2 (de)
ZA (1)	ZA865631B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4684727A (en) *	1985-07-29	1987-08-04	Schering Corporation	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
US5037826A (en) *	1986-10-15	1991-08-06	Schering Corporation	1-substituted naphthyridine and pyridopyrazine derivatives
US5045542A (en) *	1986-10-20	1991-09-03	Schering Corporation	Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives
US5350755A (en) *	1986-12-05	1994-09-27	Schering Corporation	Compounds and methods for treating hyperproliferative skin disease
CA1309658C (en) *	1986-12-05	1992-11-03	David J. Blythin	Pharmaceutical compositions for treatment of hyperproliferate skin disease
EP0362299A1 (de) *	1987-07-22	1990-04-11	Schering Corporation	Bizyklische verbindungen, deren verwendung als arzneimittel, deren herstellung und zwischenverbindungen bei ihrer herstellung
US4897487A (en) *	1988-04-06	1990-01-30	Schering Corporation	Process for preparing intermediates for pharmaceutically useful bicyclic compounds
US5180823A (en) *	1988-04-06	1993-01-19	Schering Corporation	Processes for preparing bicyclic compounds
US5079360A (en) *	1988-04-06	1992-01-07	Schering Corporation	Processes for preparing bicyclic compounds and intermediates thereof
US5341575A (en) *	1989-11-01	1994-08-30	Chisum Finis L	Apparatus to gather, display, and/or print vehicle chassis measurement data for accurate repair of collision damaged vehicles
US5175151A (en) *	1990-09-07	1992-12-29	Schering Corporation	Antiviral compounds and antihypertensive compounds
WO1992004327A1 (en) *	1990-09-07	1992-03-19	Schering Corporation	Antiviral compounds and antihypertensive compounds
US5760034A (en) *	1990-11-30	1998-06-02	Schering Corporation	Heterocyclic substituted naphthyridinones and methods and compositions employing them
GB9026389D0 (en) *	1990-12-05	1991-01-23	Merck Sharp & Dohme	Therapeutic agents
US5179093A (en) *	1991-05-10	1993-01-12	Schering Corporation	Quinoline-diones
JP2683783B2 (ja) *	1992-07-10	1997-12-03	雪印乳業株式会社	シェーグレン症候群治療剤
US7083777B1 (en) *	1999-04-02	2006-08-01	The Brigham And Women's Hospital, Inc.	Immunomodulating polymers
SV2003000753A (es)	2000-12-05	2003-06-16	Brigham & Womens Hospital	Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
JP2006522135A (ja)	2003-03-31	2006-09-28	ザブライアムアンドウィミンズホスピタルインコーポレーテッド	喘息およびアレルギーの処置のための両性イオン免疫調節剤
WO2007092451A2 (en)	2006-02-06	2007-08-16	The Brigham And Women's Hospital, Inc.	Zwitterionic polysaccharides for promotion of immune system maturation and health
US9539281B2 (en)	2011-07-12	2017-01-10	The Brigham And Women's Hospital, Inc.	Lipid-containing PSA compositions, methods of isolation and methods of use thereof
EP3337321A4 (de)	2015-08-19	2019-07-17	President and Fellows of Harvard College	Lipidierte psa-zusammensetzungen und verfahren
EP3484441A4 (de)	2016-07-15	2020-03-18	President and Fellows of Harvard College	Glycolipidzusammensetzungen und verfahren zur verwendung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4264602A (en) *	1975-08-15	1981-04-28	Sandoz, Inc.	4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones
FR2469962A1 (fr) *	1979-11-21	1981-05-29	Vallourec	Procede et dispositif pour la fabrication d'un tube d'acier sans soudure par laminage a chaud sur mandrin
EP0092786B1 (de) *	1982-04-26	1987-01-07	Schering Corporation	1,8-Naphthyridine- und 1,5,8-Azanaphthyridine-Derivate
US4452800A (en) *	1982-04-26	1984-06-05	Schering Corporation	Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases
US4551463A (en) *	1982-11-03	1985-11-05	Schering Corporation	Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug
US4628055A (en) *	1982-11-03	1986-12-09	Schering Corporation	Method for treating allergic reactions and compositions therefore
US4684727A (en) *	1985-07-29	1987-08-04	Schering Corporation	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

1985
- 1985-07-29 US US06/760,196 patent/US4684727A/en not_active Expired - Lifetime
1986
- 1986-07-25 HU HU862869A patent/HU201550B/hu not_active IP Right Cessation
- 1986-07-25 DE DE8686904707T patent/DE3684903D1/de not_active Expired - Lifetime
- 1986-07-25 KR KR1019870700274A patent/KR900003490B1/ko not_active IP Right Cessation
- 1986-07-25 WO PCT/US1986/001518 patent/WO1987000752A2/en active IP Right Grant
- 1986-07-25 JP JP61504059A patent/JPH0794455B2/ja not_active Expired - Lifetime
- 1986-07-25 EP EP86904707A patent/EP0232328B1/de not_active Expired - Lifetime
- 1986-07-25 AU AU61479/86A patent/AU597587B2/en not_active Ceased
- 1986-07-25 AT AT86904707T patent/ATE74756T1/de not_active IP Right Cessation
- 1986-07-25 PH PH34069A patent/PH23887A/en unknown
- 1986-07-28 PT PT83080A patent/PT83080B/pt not_active IP Right Cessation
- 1986-07-28 IE IE199786A patent/IE59298B1/en not_active IP Right Cessation
- 1986-07-28 ZA ZA865631A patent/ZA865631B/xx unknown
- 1986-07-29 CA CA000514897A patent/CA1263654A/en not_active Expired
- 1986-07-29 NZ NZ217016A patent/NZ217016A/xx unknown
- 1986-07-29 IL IL7955686A patent/IL79556A/en not_active IP Right Cessation
1987
- 1987-03-16 OA OA59087A patent/OA08501A/xx unknown
- 1987-03-27 NO NO871311A patent/NO166862C/no unknown
- 1987-03-27 DK DK157787A patent/DK157787A/da not_active IP Right Cessation
- 1987-03-27 FI FI871345A patent/FI871345A/fi not_active Application Discontinuation
- 1987-07-22 US US07/076,469 patent/US4782067A/en not_active Expired - Fee Related
- 1987-07-22 US US07/076,450 patent/US4794116A/en not_active Expired - Fee Related
- 1987-08-10 MY MYPI87001247A patent/MY101970A/en unknown
1988
- 1988-07-22 US US07/223,458 patent/US4902693A/en not_active Expired - Fee Related
1991
- 1991-12-30 CZ CS914139A patent/CZ413991A3/cs unknown
1992
- 1992-06-25 MX MX9203320A patent/MX9203320A/es unknown

Also Published As

Publication number	Publication date
DK157787D0 (da)	1987-03-27
JPH0794455B2 (ja)	1995-10-11
EP0232328A1 (de)	1987-08-19
MX9203320A (es)	1992-07-01
ATE74756T1 (de)	1992-05-15
WO1987000752A2 (en)	1987-02-12
PH23887A (en)	1989-12-18
AU597587B2 (en)	1990-06-07
KR870700352A (ko)	1987-12-28
CA1263654A (en)	1989-12-05
CZ413991A3 (en)	1993-01-13
WO1987000752A3 (en)	1987-05-21
IE59298B1 (en)	1994-02-09
IL79556A (en)	1995-05-26
ZA865631B (en)	1987-03-25
PT83080B (pt)	1989-01-30
DE3684903D1 (de)	1992-05-21
US4902693A (en)	1990-02-20
IE861997L (en)	1987-01-29
JPS63500453A (ja)	1988-02-18
NO871311L (no)	1987-03-27
NZ217016A (en)	1989-11-28
NO166862C (no)	1991-09-11
HU201550B (en)	1990-11-28
NO871311D0 (no)	1987-03-27
DK157787A (da)	1987-03-27
NO166862B (no)	1991-06-03
US4684727A (en)	1987-08-04
MY101970A (en)	1992-02-29
KR900003490B1 (ko)	1990-05-21
PT83080A (en)	1986-08-01
HUT42481A (en)	1987-07-28
FI871345A0 (fi)	1987-03-27
US4782067A (en)	1988-11-01
EP0232328B1 (de)	1992-04-15
US4794116A (en)	1988-12-27
AU6147986A (en)	1987-03-05
FI871345A (fi)	1987-03-27

Publication	Publication Date	Title
ZA865631B (en)	1987-03-25	Zwitterionic bicyclic compounds and their salts,solvates,hydrates and esters
BG103417A (en)	2000-06-30	Condensed pyrimidine bicyclic derivatives
PL261349A1 (en)	1987-06-29	Method of obtaining an incorporative complex of 7-isopropoxyisoflavone with cyclodextrin
IT1205849B (it)	1989-03-31	Derivati di indolo,procedimenti per prepararli e composizioni farmaceutiche che li contengono per il trattamento di emicrania
HU206701B (en)	1992-12-28	Process for producing substituted flavonoid derivatives and salts and pharmaceutical compositions containing these compounds
SG48298A1 (en)	1998-04-17	Saccharin deriatives useful as proteolytic enzymeinhibitors and preparation of
AU3192084A (en)	1985-03-21	Pharmaceutical compositions of benzothiophene derivatives
HU912013D0 (en)	1991-12-30	Process for the production of benzopyrane derivatives and their heterocyclic analogues, antiyschemic medical preparations
FR2651435B1 (de)	1994-04-22
NO891703D0 (no)	1989-04-25	Farmasoeytiske sammensetninger for behandling av psoriasis.
IL95849A0 (en)	1991-06-30	Pharmaceutical combination containing acetylsalicylic acid and carbacyclin derivatives
MY103593A (en)	1993-08-28	Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
AU3760489A (en)	1989-12-12	Derivatives of cyclic amp as treatment for cancer
PL256941A1 (en)	1986-10-07	Method of obtaining n-substituted derivatives of azidrin-2-carboxylic acid
GR3005231T3 (de)	1993-05-24
IL66192A (en)	1985-08-30	Albomycin derivatives,their production and pharmaceutical compositions containing them
HUP9801985A3 (en)	2000-07-28	Use of cystine derivatives for the preparation of pharmaceutical compositions useful for the treatment of restenosis
IL67672A0 (en)	1983-05-15	Penicillin derivatives,their preparation and pharmaceutical compositions containing them
ITMI921125A1 (it)	1993-11-11	Procedimento per la preparazione di derivati beta-lattamici alogenati
IT1269740B (it)	1997-04-15	Derivati di combretastatine ad attivita' anti-tumorale e procedimento per la loro preparazione
MX9100344A (es)	1992-02-28	Procedimientos para la preparacion de derivados de 6-(3-aminopropionilo substituido)-7-desacetilforscolina
IT1243368B (it)	1994-06-10	Uso del bendazac e dei suoi sali farmaceuticamente accettabili
GR850484B (de)	1985-06-26