PT83080B - Processo para a preparacao de compostos biciclicos, de naftiridina ou seus analogos, e dos seus sais, solvatos, hidratos e esteres - Google Patents

Processo para a preparacao de compostos biciclicos, de naftiridina ou seus analogos, e dos seus sais, solvatos, hidratos e esteres

Info

Publication number: PT83080B
Authority: PT; Portugal
Prior art keywords: esters; naftiridine; solvates; hydrates; analogs
Prior art date: 1985-07-29

Application number

PT83080A

Other languages

English (en)

Other versions

PT83080A (en

Inventor

David John Blythin

Ho-Jane Shue

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-29

Filing date

1986-07-28

Publication date

1989-01-30

1986-07-28 Application filed by Schering Corp filed Critical Schering Corp

1986-08-01 Publication of PT83080A publication Critical patent/PT83080A/pt

1989-01-30 Publication of PT83080B publication Critical patent/PT83080B/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Transplantation (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)
Professional, Industrial, Or Sporting Protective Garments (AREA)
Outer Garments And Coats (AREA)

PT83080A 1985-07-29 1986-07-28 Processo para a preparacao de compostos biciclicos, de naftiridina ou seus analogos, e dos seus sais, solvatos, hidratos e esteres PT83080B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/760,196 US4684727A (en)	1985-07-29	1985-07-29	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

Publications (2)

Publication Number	Publication Date
PT83080A PT83080A (en)	1986-08-01
PT83080B true PT83080B (pt)	1989-01-30

Family

ID=25058394

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT83080A PT83080B (pt)	1985-07-29	1986-07-28	Processo para a preparacao de compostos biciclicos, de naftiridina ou seus analogos, e dos seus sais, solvatos, hidratos e esteres

Country Status (23)

Country	Link
US (4)	US4684727A (pt)
EP (1)	EP0232328B1 (pt)
JP (1)	JPH0794455B2 (pt)
KR (1)	KR900003490B1 (pt)
AT (1)	ATE74756T1 (pt)
AU (1)	AU597587B2 (pt)
CA (1)	CA1263654A (pt)
CZ (1)	CZ413991A3 (pt)
DE (1)	DE3684903D1 (pt)
DK (1)	DK157787A (pt)
FI (1)	FI871345A (pt)
HU (1)	HU201550B (pt)
IE (1)	IE59298B1 (pt)
IL (1)	IL79556A (pt)
MX (1)	MX9203320A (pt)
MY (1)	MY101970A (pt)
NO (1)	NO166862C (pt)
NZ (1)	NZ217016A (pt)
OA (1)	OA08501A (pt)
PH (1)	PH23887A (pt)
PT (1)	PT83080B (pt)
WO (1)	WO1987000752A2 (pt)
ZA (1)	ZA865631B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4684727A (en) *	1985-07-29	1987-08-04	Schering Corporation	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
US5037826A (en) *	1986-10-15	1991-08-06	Schering Corporation	1-substituted naphthyridine and pyridopyrazine derivatives
US5045542A (en) *	1986-10-20	1991-09-03	Schering Corporation	Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives
US5350755A (en) *	1986-12-05	1994-09-27	Schering Corporation	Compounds and methods for treating hyperproliferative skin disease
CA1309658C (en) *	1986-12-05	1992-11-03	David J. Blythin	Pharmaceutical compositions for treatment of hyperproliferate skin disease
EP0362299A1 (en) *	1987-07-22	1990-04-11	Schering Corporation	Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
US4897487A (en) *	1988-04-06	1990-01-30	Schering Corporation	Process for preparing intermediates for pharmaceutically useful bicyclic compounds
US5180823A (en) *	1988-04-06	1993-01-19	Schering Corporation	Processes for preparing bicyclic compounds
US5079360A (en) *	1988-04-06	1992-01-07	Schering Corporation	Processes for preparing bicyclic compounds and intermediates thereof
US5341575A (en) *	1989-11-01	1994-08-30	Chisum Finis L	Apparatus to gather, display, and/or print vehicle chassis measurement data for accurate repair of collision damaged vehicles
US5175151A (en) *	1990-09-07	1992-12-29	Schering Corporation	Antiviral compounds and antihypertensive compounds
WO1992004327A1 (en) *	1990-09-07	1992-03-19	Schering Corporation	Antiviral compounds and antihypertensive compounds
US5760034A (en) *	1990-11-30	1998-06-02	Schering Corporation	Heterocyclic substituted naphthyridinones and methods and compositions employing them
GB9026389D0 (en) *	1990-12-05	1991-01-23	Merck Sharp & Dohme	Therapeutic agents
US5179093A (en) *	1991-05-10	1993-01-12	Schering Corporation	Quinoline-diones
JP2683783B2 (ja) *	1992-07-10	1997-12-03	雪印乳業株式会社	シェーグレン症候群治療剤
US7083777B1 (en) *	1999-04-02	2006-08-01	The Brigham And Women's Hospital, Inc.	Immunomodulating polymers
SV2003000753A (es)	2000-12-05	2003-06-16	Brigham & Womens Hospital	Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
JP2006522135A (ja)	2003-03-31	2006-09-28	ザブライアムアンドウィミンズホスピタルインコーポレーテッド	喘息およびアレルギーの処置のための両性イオン免疫調節剤
WO2007092451A2 (en)	2006-02-06	2007-08-16	The Brigham And Women's Hospital, Inc.	Zwitterionic polysaccharides for promotion of immune system maturation and health
US9539281B2 (en)	2011-07-12	2017-01-10	The Brigham And Women's Hospital, Inc.	Lipid-containing PSA compositions, methods of isolation and methods of use thereof
EP3337321A4 (en)	2015-08-19	2019-07-17	President and Fellows of Harvard College	LIPIDED PSA COMPOSITIONS AND METHOD
EP3484441A4 (en)	2016-07-15	2020-03-18	President and Fellows of Harvard College	GLYCOLIPID COMPOSITIONS AND METHODS OF USE

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4264602A (en) *	1975-08-15	1981-04-28	Sandoz, Inc.	4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones
FR2469962A1 (fr) *	1979-11-21	1981-05-29	Vallourec	Procede et dispositif pour la fabrication d'un tube d'acier sans soudure par laminage a chaud sur mandrin
EP0092786B1 (en) *	1982-04-26	1987-01-07	Schering Corporation	1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
US4452800A (en) *	1982-04-26	1984-06-05	Schering Corporation	Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases
US4551463A (en) *	1982-11-03	1985-11-05	Schering Corporation	Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug
US4628055A (en) *	1982-11-03	1986-12-09	Schering Corporation	Method for treating allergic reactions and compositions therefore
US4684727A (en) *	1985-07-29	1987-08-04	Schering Corporation	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

1985
- 1985-07-29 US US06/760,196 patent/US4684727A/en not_active Expired - Lifetime
1986
- 1986-07-25 HU HU862869A patent/HU201550B/hu not_active IP Right Cessation
- 1986-07-25 DE DE8686904707T patent/DE3684903D1/de not_active Expired - Lifetime
- 1986-07-25 KR KR1019870700274A patent/KR900003490B1/ko not_active IP Right Cessation
- 1986-07-25 WO PCT/US1986/001518 patent/WO1987000752A2/en active IP Right Grant
- 1986-07-25 JP JP61504059A patent/JPH0794455B2/ja not_active Expired - Lifetime
- 1986-07-25 EP EP86904707A patent/EP0232328B1/en not_active Expired - Lifetime
- 1986-07-25 AU AU61479/86A patent/AU597587B2/en not_active Ceased
- 1986-07-25 AT AT86904707T patent/ATE74756T1/de not_active IP Right Cessation
- 1986-07-25 PH PH34069A patent/PH23887A/en unknown
- 1986-07-28 PT PT83080A patent/PT83080B/pt not_active IP Right Cessation
- 1986-07-28 IE IE199786A patent/IE59298B1/en not_active IP Right Cessation
- 1986-07-28 ZA ZA865631A patent/ZA865631B/xx unknown
- 1986-07-29 CA CA000514897A patent/CA1263654A/en not_active Expired
- 1986-07-29 NZ NZ217016A patent/NZ217016A/xx unknown
- 1986-07-29 IL IL7955686A patent/IL79556A/en not_active IP Right Cessation
1987
- 1987-03-16 OA OA59087A patent/OA08501A/xx unknown
- 1987-03-27 NO NO871311A patent/NO166862C/no unknown
- 1987-03-27 DK DK157787A patent/DK157787A/da not_active IP Right Cessation
- 1987-03-27 FI FI871345A patent/FI871345A/fi not_active Application Discontinuation
- 1987-07-22 US US07/076,469 patent/US4782067A/en not_active Expired - Fee Related
- 1987-07-22 US US07/076,450 patent/US4794116A/en not_active Expired - Fee Related
- 1987-08-10 MY MYPI87001247A patent/MY101970A/en unknown
1988
- 1988-07-22 US US07/223,458 patent/US4902693A/en not_active Expired - Fee Related
1991
- 1991-12-30 CZ CS914139A patent/CZ413991A3/cs unknown
1992
- 1992-06-25 MX MX9203320A patent/MX9203320A/es unknown

Also Published As

Publication number	Publication date
DK157787D0 (da)	1987-03-27
JPH0794455B2 (ja)	1995-10-11
EP0232328A1 (en)	1987-08-19
MX9203320A (es)	1992-07-01
ATE74756T1 (de)	1992-05-15
WO1987000752A2 (en)	1987-02-12
OA08501A (en)	1988-07-29
PH23887A (en)	1989-12-18
AU597587B2 (en)	1990-06-07
KR870700352A (ko)	1987-12-28
CA1263654A (en)	1989-12-05
CZ413991A3 (en)	1993-01-13
WO1987000752A3 (en)	1987-05-21
IE59298B1 (en)	1994-02-09
IL79556A (en)	1995-05-26
ZA865631B (en)	1987-03-25
DE3684903D1 (de)	1992-05-21
US4902693A (en)	1990-02-20
IE861997L (en)	1987-01-29
JPS63500453A (ja)	1988-02-18
NO871311L (no)	1987-03-27
NZ217016A (en)	1989-11-28
NO166862C (no)	1991-09-11
HU201550B (en)	1990-11-28
NO871311D0 (no)	1987-03-27
DK157787A (da)	1987-03-27
NO166862B (no)	1991-06-03
US4684727A (en)	1987-08-04
MY101970A (en)	1992-02-29
KR900003490B1 (ko)	1990-05-21
PT83080A (en)	1986-08-01
HUT42481A (en)	1987-07-28
FI871345A0 (fi)	1987-03-27
US4782067A (en)	1988-11-01
EP0232328B1 (en)	1992-04-15
US4794116A (en)	1988-12-27
AU6147986A (en)	1987-03-05
FI871345A (fi)	1987-03-27

Publication	Publication Date	Title
PT83080B (pt)	1989-01-30	Processo para a preparacao de compostos biciclicos, de naftiridina ou seus analogos, e dos seus sais, solvatos, hidratos e esteres
PT82580B (pt)	1989-01-17	Processo para a preparacao de 2',3'- didesoxinucleosidos e de composicoes farmaceuticas que os contem
SE8602723D0 (sv)	1986-06-18	Thiazoles, their production and pharmaceutical compositions containing them
IT8268024A0 (it)	1982-08-19	Per la loro preparazione e composi carbapenem derivati procedimento zioni farmaceutiche contenenti tali derivati come agenti antibatterici
PT83933B (pt)	1989-01-17	Processo para a preparacao de composicoes estaveis de activador do plasminogenio humano, tipo tecido
MX23889A (es)	1993-10-01	Derivados de cromanos y tiocromanos, procedimiento para su preparacion y composicion farmaceutica.
ES555200A0 (es)	1988-05-01	Procedimiento para la produccion de derivados del morfinano
DK627289D0 (da)	1989-12-12	Anvendelse af bicyclononanderivater
IT8948702A0 (it)	1989-12-28	Derivati gangliosidici, loro uso quali agenti terapeutici, procedimento per la loro produzione e composti farmaceutici che li contengono
SE8306225L (sv)	1984-05-13	2-piperazinyl-kinazolinderivat, deras framstellning och farmaceutiska kompositioner innehallande desamma
ES556137A0 (es)	1988-01-01	Un procedimiento para preparar derivados de penem
ES550285A0 (es)	1987-11-01	Procedimiento para preparar derivados de acidos aziridin-2- carboxilicos substituidos en n
IT1235761B (it)	1992-09-28	Derivati biciclici del catecolo, procedimento per la loro preparazione e composizioni terapeutiche che li contengono
IT8748656A0 (it)	1987-12-01	Derivati azolici,procedimento per la loro produzione,preparati farmaceutici che li contengono,e loro impiego
ES532445A0 (es)	1985-02-01	Procedimiento para preparar 2-alquiltio-1-aminoalquil-2-pirrolin-3-carbonitrilos
SE8900685D0 (sv)	1989-02-28	New compounds
IT8619969A0 (it)	1986-04-03	Derivati del ferro, procedimento per la loro produzione e relative composizioni farmaceutiche

Legal Events

Date	Code	Title	Description
1996-05-31	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960131

Date

Code

Title

Description

1996-05-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960131