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OA07172A - Nouvelles thiazolidinediones, leur procédé de production et préparation pharmaceutique les contenant. - Google Patents

Nouvelles thiazolidinediones, leur procédé de production et préparation pharmaceutique les contenant.

Info

Publication number
OA07172A
OA07172A OA57765A OA57765A OA07172A OA 07172 A OA07172 A OA 07172A OA 57765 A OA57765 A OA 57765A OA 57765 A OA57765 A OA 57765A OA 07172 A OA07172 A OA 07172A
Authority
OA
OAPI
Prior art keywords
production process
pharmaceutical preparation
preparation containing
thiazolidinediones
new
Prior art date
Application number
OA57765A
Other languages
English (en)
French (fr)
Inventor
Jr David L Temple
Richard E Yeager
Original Assignee
Bristol Myers Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Cie filed Critical Bristol Myers Cie
Publication of OA07172A publication Critical patent/OA07172A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
OA57765A 1981-08-03 1982-08-03 Nouvelles thiazolidinediones, leur procédé de production et préparation pharmaceutique les contenant. OA07172A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/289,352 US4367335A (en) 1981-08-03 1981-08-03 Thiazolidinylalkylene piperazine derivatives

Publications (1)

Publication Number Publication Date
OA07172A true OA07172A (fr) 1984-04-30

Family

ID=23111164

Family Applications (1)

Application Number Title Priority Date Filing Date
OA57765A OA07172A (fr) 1981-08-03 1982-08-03 Nouvelles thiazolidinediones, leur procédé de production et préparation pharmaceutique les contenant.

Country Status (28)

Country Link
US (1) US4367335A (it)
JP (2) JPS5826877A (it)
KR (1) KR880001478B1 (it)
AT (1) AT381705B (it)
AU (1) AU560655B2 (it)
BE (1) BE894022A (it)
CA (1) CA1172636A (it)
CH (1) CH652398A5 (it)
DE (1) DE3228990A1 (it)
DK (1) DK162991C (it)
ES (1) ES8307800A1 (it)
FI (1) FI76793C (it)
FR (1) FR2510572B1 (it)
GB (1) GB2106104B (it)
GR (1) GR76172B (it)
HU (1) HU191187B (it)
IE (1) IE53641B1 (it)
IL (1) IL66434A0 (it)
IT (1) IT1149329B (it)
LU (1) LU84316A1 (it)
NL (1) NL8203034A (it)
NZ (1) NZ201159A (it)
OA (1) OA07172A (it)
PH (1) PH18220A (it)
PT (1) PT75366B (it)
SE (1) SE452320B (it)
YU (1) YU44074B (it)
ZA (1) ZA825479B (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456756A (en) * 1981-08-03 1984-06-26 Mead Johnson & Company Spirothiazolidinyl piperazine derivatives
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4620006A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
CA1278792C (en) * 1985-05-06 1991-01-08 Joseph P. Yevich Antipsychotic fused-ring pyridinylpiperazine derivatives
US4677104A (en) * 1985-05-06 1987-06-30 Bristol-Myers Company Antipsychotic fused-ring pyridinylpiperazine derivatives
US4675403A (en) * 1985-10-16 1987-06-23 American Home Products Corporation 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity
US4784998A (en) * 1987-04-06 1988-11-15 Bristol-Myers Company 1,3,4-oxadiazole pyschotropic compounds
US5801186A (en) * 1987-11-20 1998-09-01 Hoechst Marion Roussel, Inc. 3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US5116970A (en) * 1988-02-18 1992-05-26 New James S Psychotropic heterobicycloalkylpiperazine derivatives: 2. fused pyridazinones
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
FR2642759B1 (fr) * 1989-02-09 1991-05-17 Laboratorios Esteve Sa Derives de pyrimidyl-piperazinyl-alkyl azoles avec activite anxiolytique et/ou tranquillisante
JPH0415948U (it) * 1990-05-31 1992-02-10
US5130315A (en) * 1991-01-10 1992-07-14 Raymond R. Wittekind 1-piperazinyl-2-butenes and -2-butynes
US5194436A (en) * 1991-01-10 1993-03-16 Hoechst-Roussel Pharmaceuticals Inc. 1-piperazinyl-2-butenes and -2-butynes
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
WO2003093236A1 (en) * 2002-05-02 2003-11-13 Euro-Celtique, S.A. 1-(pyrid-2-yl)-piperazine compounds as metabotropic glutamate receptor inhibitor
WO2006013445A2 (en) * 2004-07-28 2006-02-09 Ranbaxy Laboratories Limited Thiazolidinedione derivatives as alpha adrenergic receptor antagonists

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2672460A (en) * 1952-06-24 1954-03-16 American Cyanamid Co Disubstituted piperazines and methods of preparing the same
US2748125A (en) * 1954-04-26 1956-05-29 American Cyanamid Co 1-substituted-4-sulfamylpiperazine and method of preparing the same
NL125835C (it) * 1960-05-24
FR1435004A (fr) * 1965-02-04 1966-04-15 Sobio Lab Dérivés de thiazolidine-dione-2, 4- et procédé de préparation
US3398151A (en) * 1966-02-01 1968-08-20 Mead Johnson & Co Azaspirodecanediones and azaspiroundecanediones
DE1695410A1 (de) * 1967-04-20 1971-04-08 Merck Patent Gmbh Verfahren zur Herstellung von 1-(Thiazolyl-5-alkyl)-4-(pyridyl-2)-piperazinen
US3635976A (en) * 1967-12-20 1972-01-18 Pennwalt Corp 1 - heterocyclic alkyl-1 2 3 4-tetrahydroquinazolinones and analgesic intermediates thereof
US3822266A (en) * 1968-12-24 1974-07-02 Hoffmann La Roche (3-(1-piperazinyl)-2-hydroxy-propoxy)acetanilides
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4017622A (en) * 1972-12-18 1977-04-12 Dainippon Pharmaceutical Co., Ltd. Piperazine derivatives
DE2263211A1 (de) * 1972-12-23 1974-07-04 Boehringer Sohn Ingelheim Neue arylpiperazine und verfahren zu ihrer herstellung
US3919230A (en) * 1974-02-07 1975-11-11 Smithkline Corp {62 -Naphthylmethyl piperazinyl derivatives
FR2285883A1 (fr) * 1974-09-30 1976-04-23 Cerm Cent Europ Rech Mauvernay Nouveaux composes chimiques a activite bronchospasmolytique et antitussive, et procede pour leur obtention
US3940398A (en) * 1975-01-23 1976-02-24 E. R. Squibb & Sons, Inc. 2-[[4-(Azine or diazine or triazine)-1-piperazinyl]alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
US4060615A (en) * 1976-02-18 1977-11-29 Mead Johnson & Company 2-Piperazinyl-6,7-dimethoxyquinazolines
US4001237A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company Oxazole, isoxazole, thiazole and isothiazole amides
GB1518559A (en) * 1976-04-12 1978-07-19 Science Union & Cie Naphthyl derivatives processes for their preparation an pharmaceutical compositions containing them
US4078063A (en) * 1976-09-24 1978-03-07 Merck & Co., Inc. Piperazinylpyridines
US4101548A (en) * 1977-02-22 1978-07-18 Bristol-Myers Company 1,2,3-Thiadiazole amides
HU173380B (hu) * 1977-02-25 1979-04-28 Richter Gedeon Vegyeszet Sposob poluchenija novogo proizvodnogo piridil-piperazina i kislo-additivnykh solejj
DE2727469A1 (de) * 1977-06-18 1978-12-21 Hoechst Ag Neue hexahydropyrimidine, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
EP0002978B1 (fr) * 1977-12-29 1982-10-06 Synthelabo Dérivés de thiazolidinedione-2,4, leur préparation et leur application en thérapeutique
FR2418798A1 (fr) * 1978-03-03 1979-09-28 Science Union & Cie Nouvelles piperazines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
FI791926A (fi) * 1978-06-20 1979-12-21 Synthelabo Fenylpiperazinderivat
US4161595A (en) * 1978-10-02 1979-07-17 Bristol-Myers Company Levulinic acid salt

Also Published As

Publication number Publication date
JPH0371410B2 (it) 1991-11-13
BE894022A (fr) 1983-02-03
GR76172B (it) 1984-08-03
SE452320B (sv) 1987-11-23
FI822667L (fi) 1983-02-04
DK343682A (da) 1983-02-04
IE53641B1 (en) 1989-01-04
SE8204550D0 (sv) 1982-08-02
ATA299482A (de) 1986-04-15
YU158682A (en) 1985-04-30
ZA825479B (en) 1983-04-27
ES514264A0 (es) 1983-08-01
JPH02270821A (ja) 1990-11-05
HU191187B (en) 1987-01-28
DK162991B (da) 1992-01-06
PT75366A (en) 1982-09-01
FR2510572B1 (fr) 1986-05-09
AU560655B2 (en) 1987-04-16
JPH0235754B2 (it) 1990-08-13
NL8203034A (nl) 1983-03-01
ES8307800A1 (es) 1983-08-01
FR2510572A1 (fr) 1983-02-04
GB2106104B (en) 1985-05-09
GB2106104A (en) 1983-04-07
FI822667A0 (fi) 1982-07-30
IT1149329B (it) 1986-12-03
DE3228990A1 (de) 1983-03-03
NZ201159A (en) 1985-10-11
KR880001478B1 (ko) 1988-08-13
PT75366B (en) 1985-11-20
SE8204550L (sv) 1983-02-04
KR840001167A (ko) 1984-03-28
CH652398A5 (de) 1985-11-15
JPS5826877A (ja) 1983-02-17
LU84316A1 (fr) 1983-06-07
IE821852L (en) 1983-02-03
DK162991C (da) 1992-06-01
FI76793B (fi) 1988-08-31
US4367335A (en) 1983-01-04
CA1172636A (en) 1984-08-14
AU8566382A (en) 1983-02-10
PH18220A (en) 1985-04-30
YU44074B (en) 1990-02-28
IT8248909A0 (it) 1982-07-29
IL66434A0 (en) 1982-12-31
AT381705B (de) 1986-11-25
FI76793C (fi) 1988-12-12

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