Nothing Special   »   [go: up one dir, main page]

NZ226163A - Pharmaceutical excipients comprising water soluble monoesters of a fatty acid and a polyol as solubilisers of pharmaceutical agents - Google Patents

Pharmaceutical excipients comprising water soluble monoesters of a fatty acid and a polyol as solubilisers of pharmaceutical agents

Info

Publication number
NZ226163A
NZ226163A NZ226163A NZ22616388A NZ226163A NZ 226163 A NZ226163 A NZ 226163A NZ 226163 A NZ226163 A NZ 226163A NZ 22616388 A NZ22616388 A NZ 22616388A NZ 226163 A NZ226163 A NZ 226163A
Authority
NZ
New Zealand
Prior art keywords
solubilisers
polyol
pharmaceutical
fatty acid
water soluble
Prior art date
Application number
NZ226163A
Inventor
Lorenz Hahn
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of NZ226163A publication Critical patent/NZ226163A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ226163A 1987-09-15 1988-09-13 Pharmaceutical excipients comprising water soluble monoesters of a fatty acid and a polyol as solubilisers of pharmaceutical agents NZ226163A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3730909 1987-09-15
DE3802355 1988-01-27

Publications (1)

Publication Number Publication Date
NZ226163A true NZ226163A (en) 1991-08-27

Family

ID=25859774

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ226163A NZ226163A (en) 1987-09-15 1988-09-13 Pharmaceutical excipients comprising water soluble monoesters of a fatty acid and a polyol as solubilisers of pharmaceutical agents

Country Status (24)

Country Link
JP (1) JP3090666B2 (en)
KR (1) KR0131084B1 (en)
AT (1) AT395819B (en)
AU (1) AU628787B2 (en)
BE (1) BE1001204A5 (en)
CA (1) CA1338775C (en)
CH (1) CH683672A5 (en)
DK (1) DK175132B1 (en)
ES (1) ES2012118A6 (en)
FI (1) FI94837C (en)
FR (1) FR2620336B1 (en)
GB (1) GB2209671B (en)
GR (1) GR1002243B (en)
HU (1) HU205010B (en)
IE (1) IE61195B1 (en)
IL (1) IL87746A (en)
IT (1) IT1224886B (en)
LU (1) LU87335A1 (en)
MY (1) MY103769A (en)
NL (1) NL195094C (en)
NO (1) NO179434C (en)
NZ (1) NZ226163A (en)
PT (1) PT88492B (en)
SE (1) SE503279C2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
GR1000466B (en) * 1989-01-28 1992-07-30 Sandoz Ag Preparation method of novel pharmaceutical forms of cyclosporine
GB2230440B (en) * 1989-02-09 1993-05-19 Sandoz Ltd Novel cyclosporin galenic forms
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
ES2098739T3 (en) 1992-05-13 1997-05-01 Sandoz Ltd OPHTHALMIC COMPOSITIONS CONTAINING A CYCLOSPORIN.
EP0589843B1 (en) 1992-09-25 2001-11-28 Novartis AG Pharmaceutical compositions containing cyclosporins
DE69426408T2 (en) 1993-09-28 2001-07-12 Novartis Ag, Basel Manufacture of soft gelatin capsules
ATE218359T1 (en) 1994-11-03 2002-06-15 Novartis Erfind Verwalt Gmbh NEW PREPARATION FORMS OF CYCLOSPORIN FOR ORAL APPLICATION WITH SIMPLE COMPOSITION AND HIGH BIOAVAILABILITY AND METHOD FOR THE PRODUCTION THEREOF
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
DE19544507B4 (en) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin containing preparations
TW414696B (en) * 1996-07-01 2000-12-11 Mitsubishi Kagaku Foods Kk Anti-bacteria agent
CA2278675A1 (en) 1997-01-30 1998-08-06 Novartis Ag Hard gelatine capsules containing pharmaceutical compositions substantially free of any oil
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
EP1558215A4 (en) * 2003-10-14 2007-09-12 Wockhardt Ltd Sterile gelling agents
JP5422871B2 (en) * 2006-10-24 2014-02-19 不二製油株式会社 Isoflavones composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE624258A (en) * 1961-10-31
GB1134878A (en) * 1966-05-12 1968-11-27 Suga Kazuo Improvements in and relating to oryzanol solutions and compositions
FR5986M (en) * 1966-11-22 1968-06-21
BE787842A (en) * 1971-08-25 1972-12-18 Sumito Chemical Cy Ltd PROCESS FOR PREPARING AN AQUEOUS SUSPENSION OF STABLE CRYSTALS OF THE NON-BETA TYPE OF HIGHER FATTY ACID ESTERS OF CHLORAMPHENICOL
JPS53107408A (en) * 1977-02-28 1978-09-19 Yamanouchi Pharmaceut Co Ltd Micellar preparation for rectal infusion
DE2907460A1 (en) * 1978-03-07 1979-09-13 Sandoz Ag NEW RESORBABLE GALENIC COMPOSITIONS
JPS57128634A (en) * 1981-02-03 1982-08-10 Eisai Co Ltd Elastase-containing compound increasing absorption
EP0179583A1 (en) * 1984-10-04 1986-04-30 Merck & Co. Inc. A system for enhancing the water dissolution rate and solubility of poorly soluble drugs
JPS61280435A (en) * 1985-04-04 1986-12-11 Kanji Takada Lymph orienting preparation of cyclosporin

Also Published As

Publication number Publication date
JP3090666B2 (en) 2000-09-25
IL87746A (en) 1992-07-15
FR2620336A1 (en) 1989-03-17
CH683672A5 (en) 1994-04-29
HU205010B (en) 1992-03-30
BE1001204A5 (en) 1989-08-16
GR1002243B (en) 1996-04-22
AT395819B (en) 1993-03-25
GB8821443D0 (en) 1988-10-12
KR890004694A (en) 1989-05-09
DK511188A (en) 1989-03-16
FR2620336B1 (en) 1991-10-25
GR880100602A (en) 1989-06-22
NO884052D0 (en) 1988-09-13
ATA224988A (en) 1992-08-15
NO179434B (en) 1996-07-01
PT88492B (en) 1993-03-31
SE503279C2 (en) 1996-05-13
NL195094C (en) 2003-12-17
SE8803221D0 (en) 1988-09-13
IT1224886B (en) 1990-10-24
CA1338775C (en) 1996-12-10
KR0131084B1 (en) 1998-04-17
AU628787B2 (en) 1992-09-24
MY103769A (en) 1993-09-30
GB2209671B (en) 1991-11-13
LU87335A1 (en) 1989-04-06
DK175132B1 (en) 2004-06-14
HUT49494A (en) 1989-10-30
JPH01151526A (en) 1989-06-14
IE61195B1 (en) 1994-10-19
IL87746A0 (en) 1989-02-28
FI94837B (en) 1995-07-31
PT88492A (en) 1988-10-01
FI94837C (en) 1995-11-10
NL8802275A (en) 1989-04-03
FI884192A (en) 1989-03-16
NO884052L (en) 1989-03-16
ES2012118A6 (en) 1990-03-01
IE882772L (en) 1989-03-15
AU2217288A (en) 1989-04-27
DK511188D0 (en) 1988-09-14
GB2209671A (en) 1989-05-24
FI884192A0 (en) 1988-09-13
SE8803221L (en) 1989-03-16
NO179434C (en) 1996-10-09
IT8848349A0 (en) 1988-09-14

Similar Documents

Publication Publication Date Title
NZ226163A (en) Pharmaceutical excipients comprising water soluble monoesters of a fatty acid and a polyol as solubilisers of pharmaceutical agents
HK1022248A1 (en) Use of a germicidal agent comprising an isothiocyanic acid ester
JPS6434946A (en) Manufacture of polyol fatty acid ester
IL92545A0 (en) Preparation of 2-chloropyridine-3-carboxylic acid esters
JPS6416783A (en) Bridged diazabicycloalkylquinolinecarboxylic acid and esters of same
IL87800A0 (en) Dioxolane-2-carboxylic acids and pharmaceutical compositions comprising them
IL78533A0 (en) Esters of 2-diazo-3-siloxyalkenoic acids and their preparation
JPS6416757A (en) Fatty acid polyoxyalkyl ester sulfonates and manufacture
ZA822933B (en) Aminocyclopentanol acids and esters and their preparation and pharmaceutical formulation
IL87185A (en) Preparation of quinolone- carboxylic acids
ZA885328B (en) Phenylalkenylcarboxylic acids and their esters
NZ224923A (en) 2-methoxymethyl-penem-3-carboxylic acid derivatives and pharmaceutical compositions
NZ236061A (en) Phenoxyphenyl esters of carbamic acid derivatives and pharmaceutical compositions
EP0216324A3 (en) 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid alkyl esters and their preparation
IL67041A0 (en) Aminocyclopentane acids and esters and their preparation and pharmaceutical formulation
ZA906665B (en) Use of iodopropargyl esters of a-amino acid derivatives as antimicrobial agents
IL97304A0 (en) Water soluble salts of purpuromycin and pharmaceutical formulations thereof
GB8521492D0 (en) Preparation of diesters of alkanedioic acids
GB9009916D0 (en) Preparation of acrylic acid derivatives
NZ234102A (en) Preparation of alpha-alkoxyacetic acids and their salts
NZ234101A (en) Preparation of alpha-aryloxyacetic acids and their salts
DE3266707D1 (en) Preparation of nitroarylacetic acid esters and derivatives thereof
BG51957B2 (en) Method for the preparation of fatty acid and polyethylene glycol monoesters
EP0380985A3 (en) Esters of 4-aryl-2-halogen imidazol-5-carbonic acid, their preparation and use
ZM7984A1 (en) Formulations of anthelminthics which are sparingly soluble in water and a process for their preparation

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)
ERR Error or correction

Free format text: THE OWNER HAS BEEN CORRECTED TO 890887, NOVARTIS AG, LICHTSTRASSE 35, CH-4056 BASEL, CH

Effective date: 20140409