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NO971566L - Fremgangsmåte for behandling av diabetes mellitus ved anvendelse av KGF - Google Patents

Fremgangsmåte for behandling av diabetes mellitus ved anvendelse av KGF

Info

Publication number
NO971566L
NO971566L NO971566A NO971566A NO971566L NO 971566 L NO971566 L NO 971566L NO 971566 A NO971566 A NO 971566A NO 971566 A NO971566 A NO 971566A NO 971566 L NO971566 L NO 971566L
Authority
NO
Norway
Prior art keywords
kgf
diabetes mellitus
treating diabetes
mammals
pharmaceutical compositions
Prior art date
Application number
NO971566A
Other languages
English (en)
Norwegian (no)
Other versions
NO971566D0 (no
Inventor
Sharon Lea Aukerman
Glenn Francis Pierce
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of NO971566D0 publication Critical patent/NO971566D0/no
Publication of NO971566L publication Critical patent/NO971566L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO971566A 1994-10-13 1997-04-04 Fremgangsmåte for behandling av diabetes mellitus ved anvendelse av KGF NO971566L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32334094A 1994-10-13 1994-10-13
US32347594A 1994-10-13 1994-10-13
US48782595A 1995-06-07 1995-06-07
PCT/IB1995/000992 WO1996011950A1 (en) 1994-10-13 1995-10-12 Method of treating diabetes mellitus using kgf

Publications (2)

Publication Number Publication Date
NO971566D0 NO971566D0 (no) 1997-04-04
NO971566L true NO971566L (no) 1997-04-14

Family

ID=27406268

Family Applications (2)

Application Number Title Priority Date Filing Date
NO971566A NO971566L (no) 1994-10-13 1997-04-04 Fremgangsmåte for behandling av diabetes mellitus ved anvendelse av KGF
NO19971568A NO318761B1 (no) 1994-10-13 1997-04-04 Polypeptidanalog til nativ keratinocyttvekstfaktor kalt "KGF", farmasoytisk formulering, rekombinant nukleinsyremolekyl, biologisk funksjonell vektor, prokaryot eller eukaryot vertscelle, fremgangsmate for fremstilling av en analog av KGF, anvendelse av en effektiv mengde av analogen av KGF i folge oppfinnelsen, eller deltaN23 for fremstilling av et medikament for stimulering av produksjon av ikke-fibroblastepitelceller, in vitro fremgangsmate for stimulering av produksjon av ikke-fibroblastepitelceller samt sett.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO19971568A NO318761B1 (no) 1994-10-13 1997-04-04 Polypeptidanalog til nativ keratinocyttvekstfaktor kalt "KGF", farmasoytisk formulering, rekombinant nukleinsyremolekyl, biologisk funksjonell vektor, prokaryot eller eukaryot vertscelle, fremgangsmate for fremstilling av en analog av KGF, anvendelse av en effektiv mengde av analogen av KGF i folge oppfinnelsen, eller deltaN23 for fremstilling av et medikament for stimulering av produksjon av ikke-fibroblastepitelceller, in vitro fremgangsmate for stimulering av produksjon av ikke-fibroblastepitelceller samt sett.

Country Status (23)

Country Link
EP (2) EP0804479B1 (pt)
JP (2) JP4216329B2 (pt)
KR (1) KR100278597B1 (pt)
CN (1) CN1168678A (pt)
AT (2) ATE237633T1 (pt)
AU (1) AU3707795A (pt)
BG (2) BG101392A (pt)
BR (2) BR9509329A (pt)
CA (2) CA2201940C (pt)
CZ (3) CZ297329B6 (pt)
DE (2) DE69535264T2 (pt)
DK (2) DK0804479T3 (pt)
EE (2) EE9700225A (pt)
ES (2) ES2196082T3 (pt)
FI (2) FI971420A0 (pt)
HU (2) HUT78050A (pt)
NO (2) NO971566L (pt)
NZ (2) NZ505502A (pt)
PL (2) PL320484A1 (pt)
PT (2) PT785948E (pt)
SI (2) SI0785948T1 (pt)
SK (2) SK284534B6 (pt)
WO (2) WO1996011949A2 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEP20022681B (en) 1989-01-31 2002-04-25 Aaronson Us Stuart A Protein KFG, Antibodies, Pharmaceutical Composition, Their Use, recombinant DNA, Cell, Method for Discoveries and Production of Proteins, Method for Stimulation of Epithelial Cells Growth
US7084119B2 (en) 1993-06-29 2006-08-01 Chiron Corporation Truncated keratinocyte growth factor (KGF) having increased biological activity
DK0706563T3 (da) 1993-06-29 2005-01-31 Chiron Corp Afkortet keratonocyt-vækstfaktor (KGF) med foröget biologisk aktivetet
PT785949E (pt) * 1994-10-13 2003-09-30 Amgen Inc Metodo para purificar factores de crescimento de queratinocitos
US6077692A (en) 1995-02-14 2000-06-20 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US6693077B1 (en) 1995-02-14 2004-02-17 Human Genome Sciences, Inc. Keratinocyte growth factor-2
US7232667B2 (en) 1995-02-14 2007-06-19 Human Genome Sciences, Inc. Keratinocyte growth factor-2 polynucleotides
DK0822943T3 (da) * 1995-04-27 1999-11-29 Cooperatie Cosun U A Inulinderivater
SI0935652T1 (en) * 1996-10-15 2004-06-30 Amgen Inc. Keratinocyte growth factor-2 products
US6743422B1 (en) 1996-10-15 2004-06-01 Amgen, Inc. Keratinocyte growth factor-2 products
ES2218666T3 (es) * 1996-10-15 2004-11-16 Amgen Inc., Producto a base del factor de crecimiento de queratinocitos-2 (kggf-2).
US7153943B2 (en) 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
ES2297889T3 (es) 1997-07-14 2008-05-01 Bolder Biotechnology, Inc. Derivados de hormona de crecimiento y proteinas relacionadas.
US20080076706A1 (en) 1997-07-14 2008-03-27 Bolder Biotechnology, Inc. Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
US7495087B2 (en) 1997-07-14 2009-02-24 Bolder Biotechnology, Inc. Cysteine muteins in the C-D loop of human interleukin-11
US6869927B1 (en) 1997-12-22 2005-03-22 Human Genome Sciences, Inc. Keratinocyte growth factor-2 formulations
EP1041996A4 (en) 1997-12-22 2003-05-14 Human Genome Sciences Inc KERATINOCYTE GROWTH FACTOR-2 FORMULATIONS
US6242666B1 (en) 1998-12-16 2001-06-05 The Scripps Research Institute Animal model for identifying a common stem/progenitor to liver cells and pancreatic cells
JP2002534119A (ja) * 1999-01-14 2002-10-15 ボルダー バイオテクノロジー, インコーポレイテッド 自由システイン残基を有するタンパク質の生産方法
US8288126B2 (en) 1999-01-14 2012-10-16 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US6248725B1 (en) 1999-02-23 2001-06-19 Amgen, Inc. Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
MXPA03006988A (es) * 2001-02-06 2003-11-18 Merck Patent Gmbh Factor de crecimiento de queratinocitos (kgf) modificado con inmunogenicidad reducida.
AU2007214362B2 (en) * 2001-08-21 2009-11-26 Novartis Vaccines And Diagnostics, Inc. KGF polypeptide compositions
AU2002326742B2 (en) * 2001-08-21 2007-05-31 Novartis Vaccines And Diagnostics, Inc. KGF polypeptide compositions
EP1827483B1 (en) 2004-12-15 2014-07-02 Swedish Orphan Biovitrum AB (publ) Therapeutic formulations of keratinocyte growth factor
CN102242124B (zh) * 2010-05-10 2013-05-22 齐鲁制药有限公司 改造的角化细胞生长因子基因及其在酵母中的表达
KR102440312B1 (ko) * 2020-08-28 2022-09-05 한국해양과학기술원 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
JPH01137994A (ja) * 1987-08-10 1989-05-30 Shionogi & Co Ltd reg蛋白質
US5145225A (en) * 1988-07-27 1992-09-08 Muller George M Carpet stretcher
GEP20022681B (en) * 1989-01-31 2002-04-25 Aaronson Us Stuart A Protein KFG, Antibodies, Pharmaceutical Composition, Their Use, recombinant DNA, Cell, Method for Discoveries and Production of Proteins, Method for Stimulation of Epithelial Cells Growth
JP3303211B2 (ja) * 1991-04-26 2002-07-15 武田薬品工業株式会社 bFGFムテインおよびその製造法
IL109122A (en) * 1993-03-26 2004-07-25 Amgen Inc Use of products from a keratinocytic growth factor for the preparation of medicinal preparations
US5348563A (en) * 1993-06-29 1994-09-20 Honeywell Inc. Air purifying apparatus
DK0706563T3 (da) * 1993-06-29 2005-01-31 Chiron Corp Afkortet keratonocyt-vækstfaktor (KGF) med foröget biologisk aktivetet
GB9315501D0 (en) * 1993-07-27 1993-09-08 Ici Plc Surfactant compositions
WO1995003831A1 (en) * 1993-08-02 1995-02-09 Prizm Pharmaceuticals, Inc. Monogenous preparations of cytotoxic conjugates

Also Published As

Publication number Publication date
PT804479E (pt) 2007-02-28
NO971568L (no) 1997-06-12
DK0804479T3 (da) 2007-01-29
BR9509269A (pt) 1997-12-23
AU3708395A (en) 1996-05-06
DE69530403T2 (de) 2003-10-30
HUT78050A (hu) 1999-07-28
ATE342278T1 (de) 2006-11-15
DK0785948T3 (da) 2003-08-04
CA2201940A1 (en) 1996-04-25
HU226168B1 (en) 2008-05-28
SK43197A3 (en) 1999-03-12
FI971536A0 (fi) 1997-04-11
NO318761B1 (no) 2005-05-02
CZ105097A3 (cs) 1998-10-14
BG101392A (en) 1997-10-31
CZ98197A3 (cs) 1998-11-11
PL319784A1 (en) 1997-08-18
CA2202075A1 (en) 1996-04-25
SI0785948T1 (en) 2003-08-31
AU681546B2 (en) 1997-08-28
ES2273338T3 (es) 2007-05-01
WO1996011950A1 (en) 1996-04-25
CZ297328B6 (cs) 2006-11-15
NZ505502A (en) 2005-01-28
DE69535264D1 (de) 2006-11-23
EE03975B1 (et) 2003-02-17
FI971536A (fi) 1997-06-09
KR100278597B1 (ko) 2001-01-15
JP4216329B2 (ja) 2009-01-28
CA2201940C (en) 2009-05-12
ES2196082T3 (es) 2003-12-16
SK284534B6 (sk) 2005-06-02
FI971420A (fi) 1997-04-04
EP0804479B1 (en) 2006-10-11
PL320484A1 (en) 1997-09-29
BR9509329A (pt) 1997-10-14
EP0785948A1 (en) 1997-07-30
JPH10507193A (ja) 1998-07-14
HUT78058A (hu) 1999-07-28
JP4426646B2 (ja) 2010-03-03
FI971420A0 (fi) 1997-04-04
CZ297329B6 (cs) 2006-11-15
DE69535264T2 (de) 2007-02-01
WO1996011949A2 (en) 1996-04-25
SI0804479T1 (sl) 2006-12-31
WO1996011949A3 (en) 1996-12-12
FI120040B (fi) 2009-06-15
EP0785948B1 (en) 2003-04-16
NO971568D0 (no) 1997-04-04
JPH10507080A (ja) 1998-07-14
SK45597A3 (en) 1999-02-11
CA2202075C (en) 2003-12-09
ATE237633T1 (de) 2003-05-15
BG63167B1 (bg) 2001-05-31
AU3707795A (en) 1996-05-06
EE9700225A (et) 1998-02-16
CN1168678A (zh) 1997-12-24
EE9700081A (et) 1997-10-15
DE69530403D1 (de) 2003-05-22
NZ335109A (en) 2000-08-25
NO971566D0 (no) 1997-04-04
PT785948E (pt) 2003-09-30
PL182888B1 (pl) 2002-03-29
BG101408A (en) 1997-12-30
EP0804479A1 (en) 1997-11-05

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