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NO893616D0 - Fremgangsmaate for fremstilling av terapeutisk aktive tricykliske forbindelser. - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive tricykliske forbindelser.

Info

Publication number
NO893616D0
NO893616D0 NO893616A NO893616A NO893616D0 NO 893616 D0 NO893616 D0 NO 893616D0 NO 893616 A NO893616 A NO 893616A NO 893616 A NO893616 A NO 893616A NO 893616 D0 NO893616 D0 NO 893616D0
Authority
NO
Norway
Prior art keywords
procedure
preparation
therapeutic active
tricyclic compounds
active tricyclic
Prior art date
Application number
NO893616A
Other languages
English (en)
Other versions
NO171913B (no
NO893616L (no
NO171913C (no
Inventor
Yoshinari Sato
Teruaki Matuo
Takatomo Ogahara
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888821257A external-priority patent/GB8821257D0/en
Priority claimed from GB888829265A external-priority patent/GB8829265D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of NO893616D0 publication Critical patent/NO893616D0/no
Publication of NO893616L publication Critical patent/NO893616L/no
Publication of NO171913B publication Critical patent/NO171913B/no
Publication of NO171913C publication Critical patent/NO171913C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO893616A 1988-09-09 1989-09-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive tricykliske forbindelser NO171913C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888821257A GB8821257D0 (en) 1988-09-09 1988-09-09 Tricyclic compounds
GB888829265A GB8829265D0 (en) 1988-12-15 1988-12-15 Tricyclic compounds

Publications (4)

Publication Number Publication Date
NO893616D0 true NO893616D0 (no) 1989-09-08
NO893616L NO893616L (no) 1990-03-12
NO171913B NO171913B (no) 1993-02-08
NO171913C NO171913C (no) 1993-05-19

Family

ID=26294376

Family Applications (1)

Application Number Title Priority Date Filing Date
NO893616A NO171913C (no) 1988-09-09 1989-09-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive tricykliske forbindelser

Country Status (18)

Country Link
US (2) US4981847A (no)
EP (1) EP0360079B1 (no)
JP (3) JPH0665673B2 (no)
KR (1) KR900004737A (no)
CN (1) CN1022187C (no)
AU (1) AU628370B2 (no)
DE (1) DE68912858T2 (no)
DK (1) DK444789A (no)
ES (1) ES2061848T3 (no)
FI (1) FI92401C (no)
HK (1) HK101996A (no)
HU (2) HUT54152A (no)
IE (1) IE62916B1 (no)
IL (1) IL91361A (no)
NO (1) NO171913C (no)
PH (1) PH27358A (no)
PT (1) PT91664B (no)
RU (1) RU2007406C1 (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630440B1 (fr) * 1988-04-25 1991-09-20 Jouveinal Sa Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique
US5248679A (en) * 1988-09-09 1993-09-28 Fujisawa Pharmaceutical Co., Ltd. Tricyclic compounds
IL91361A (en) * 1988-09-09 1994-10-07 Fujisawa Pharmaceutical Co Benzodiazepinone compounds [4,1] connected via positions 1 and 9 and carrying two transducers, processes for their preparation and pharmaceutical preparations containing them
IL93401A (en) * 1989-03-08 1994-08-26 Kali Chemie Pharma Gmbh H1 - Indole - 2 - Carboxylic acid 1, 7 - Consolidated N -) 1, 4 - Benzodiazepine - 3 - Il (amides, their preparation and drugs containing them
FR2652352A1 (fr) * 1989-09-28 1991-03-29 Jouveinal Sa Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique.
GB9018601D0 (en) * 1990-08-24 1990-10-10 Fujisawa Pharmaceutical Co Tricyclic compounds
CA2056809A1 (en) * 1990-12-07 1992-06-08 Mark G. Bock Benzodiazepine analogs
EP0572235A3 (en) * 1992-05-28 1994-06-01 Tanabe Seiyaku Co Beta-carboline derivatives with anticholecystoquinine activity
GB2271354A (en) * 1992-10-07 1994-04-13 Merck Sharp & Dohme Tricyclic derivatives of benzodiazepines
WO1994020143A1 (en) * 1993-03-03 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Optical isomerization inhibitor
KR100235161B1 (ko) * 1993-11-26 2001-11-22 찌바따 이찌로, 다나까 도시오 2-옥소인돌린 유도체
US5763437A (en) * 1994-07-29 1998-06-09 Fujisawa Pharmaceutical Co., Ltd. Benzodiazepine derivatives
WO1996006617A1 (en) * 1994-08-30 1996-03-07 Fujisawa Pharmaceutical Co., Ltd. Liposome preparation
FR2725719B1 (fr) * 1994-10-14 1996-12-06 Jouveinal Inst Rech Diazepino-indoles inhibiteurs de phosphodiesterases iv
US5716958A (en) 1994-10-27 1998-02-10 Tobishi Pharmaceutical Co., Ltd. Amino acid derivative having anti-CCK activity
AUPO284396A0 (en) 1996-10-08 1996-10-31 Fujisawa Pharmaceutical Co., Ltd. Benzodiazepine derivatives
FR2776660B1 (fr) * 1998-03-27 2000-05-12 Parke Davis Diazepino-indoles de phosphodiesterases iv
WO2014047369A1 (en) 2012-09-21 2014-03-27 Bristol-Myers Squibb Company Substituted 1,5-benzodiazepinone compounds
WO2014047397A1 (en) 2012-09-21 2014-03-27 Bristol-Myers Squibb Company Fluoroalkyl and fluorocycloalkyl 1,4-benzodiazepinone compounds as notch|inhibitors
WO2014047370A1 (en) 2012-09-21 2014-03-27 Bristol-Myers Squibb Company Fluoroalkyl dibenzodiazepinone compounds
EP2897947B1 (en) 2012-09-21 2016-10-26 Bristol-Myers Squibb Company Alkyl, fluoroalkyl-1,4-benzodiazepinone compounds
JP2015531792A (ja) 2012-09-21 2015-11-05 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 1,4−ベンゾジアゼピノン化合物のプロドラッグ
JP2015529251A (ja) 2012-09-21 2015-10-05 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Notch阻害剤としての三環系複素環式化合物
EP2897954B1 (en) 2012-09-21 2016-10-26 Bristol-Myers Squibb Company Fluoroalkyl-1,4-benzodiazepinone compounds
JP2015533811A (ja) 2012-09-21 2015-11-26 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company N−置換ビス(フルオロアルキル)1,4−ベンゾジアゼピノン化合物
US9492469B2 (en) 2013-04-04 2016-11-15 Bristol-Myers Squibb Company Combination therapy for the treatment of proliferative diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3651083A (en) * 1969-11-03 1972-03-21 Upjohn Co Tetra- and hexahydro-phenylpyrrolo benzodiazepines and intermediates
AU2733371A (en) * 1970-04-14 1972-10-12 A. H. Robins Company, Incorporated 5, 7-DISUBSTITUTED-l, 9-ALKYLENE-l, 4-BENZODIAZEPIN-2 ONES
US3794646A (en) * 1970-04-14 1974-02-26 Robins Co Inc A H 5,7-disubstituted-1,9-tetramethylene-1,4-benzodiazepin-2-ones
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4735941A (en) * 1986-12-23 1988-04-05 Merck & Co., Inc. 1,4-benzodiazepines with 5- and 6-membered heterocyclic rings, useful as gastrointestinal and CNS agents
FR2630440B1 (fr) * 1988-04-25 1991-09-20 Jouveinal Sa Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique
IL91361A (en) * 1988-09-09 1994-10-07 Fujisawa Pharmaceutical Co Benzodiazepinone compounds [4,1] connected via positions 1 and 9 and carrying two transducers, processes for their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
EP0360079B1 (en) 1994-02-02
JPH0748373A (ja) 1995-02-21
HK101996A (en) 1996-06-21
FI894169A (fi) 1990-03-10
NO171913B (no) 1993-02-08
AU628370B2 (en) 1992-09-17
HUT54152A (en) 1991-01-28
CN1040981A (zh) 1990-04-04
EP0360079A1 (en) 1990-03-28
IL91361A (en) 1994-10-07
US5155101A (en) 1992-10-13
JP2848230B2 (ja) 1999-01-20
KR900004737A (ko) 1990-04-12
US4981847A (en) 1991-01-01
FI894169A0 (fi) 1989-09-05
PT91664B (pt) 1995-05-31
JPH02111774A (ja) 1990-04-24
DE68912858D1 (de) 1994-03-17
ES2061848T3 (es) 1994-12-16
PH27358A (en) 1993-06-21
DK444789A (da) 1990-03-10
AU4025789A (en) 1990-03-15
DK444789D0 (da) 1989-09-08
NO893616L (no) 1990-03-12
HU211264A9 (en) 1995-11-28
IE892840L (en) 1990-03-09
JPH0665673B2 (ja) 1994-08-24
RU2007406C1 (ru) 1994-02-15
FI92401C (fi) 1994-11-10
IL91361A0 (en) 1990-03-19
IE62916B1 (en) 1995-03-08
JPH0741480A (ja) 1995-02-10
NO171913C (no) 1993-05-19
FI92401B (fi) 1994-07-29
DE68912858T2 (de) 1994-06-01
PT91664A (pt) 1990-03-30
CN1022187C (zh) 1993-09-22

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