NO20091842L - Diagnose og behandling av kreft ved a anvende anti-EREG-antistoff - Google Patents
Diagnose og behandling av kreft ved a anvende anti-EREG-antistoffInfo
- Publication number
- NO20091842L NO20091842L NO20091842A NO20091842A NO20091842L NO 20091842 L NO20091842 L NO 20091842L NO 20091842 A NO20091842 A NO 20091842A NO 20091842 A NO20091842 A NO 20091842A NO 20091842 L NO20091842 L NO 20091842L
- Authority
- NO
- Norway
- Prior art keywords
- ereg
- cancer
- diagnosis
- antibody
- protein
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/485—Epidermal growth factor [EGF] (urogastrone)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Optics & Photonics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006278819 | 2006-10-12 | ||
PCT/JP2007/069988 WO2008047723A1 (en) | 2006-10-12 | 2007-10-12 | Diagnosis and treatment of cancer using anti-ereg antibody |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20091842L true NO20091842L (no) | 2009-07-13 |
Family
ID=39313954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20091842A NO20091842L (no) | 2006-10-12 | 2009-05-11 | Diagnose og behandling av kreft ved a anvende anti-EREG-antistoff |
Country Status (16)
Country | Link |
---|---|
US (1) | US9017684B2 (ru) |
EP (1) | EP2070548B1 (ru) |
JP (2) | JP5687822B2 (ru) |
KR (1) | KR101493779B1 (ru) |
CN (2) | CN103396486A (ru) |
AU (1) | AU2007312367B2 (ru) |
BR (1) | BRPI0719202A2 (ru) |
CA (1) | CA2665528C (ru) |
IL (2) | IL197914A (ru) |
MX (1) | MX2009003738A (ru) |
MY (1) | MY162056A (ru) |
NO (1) | NO20091842L (ru) |
NZ (2) | NZ576855A (ru) |
RU (2) | RU2537245C2 (ru) |
UA (1) | UA106194C2 (ru) |
WO (1) | WO2008047723A1 (ru) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2070548B1 (en) | 2006-10-12 | 2017-01-18 | Chugai Seiyaku Kabushiki Kaisha | Diagnosis and treatment of cancer using anti-ereg antibody |
WO2009051974A1 (en) * | 2007-10-17 | 2009-04-23 | Nuvelo, Inc. | Antibodes to cll-1 |
CN102099458A (zh) | 2008-06-05 | 2011-06-15 | 威斯康星医学院公司 | 用于高通量试验的三维组织 |
PT2406286T (pt) * | 2009-03-10 | 2016-08-19 | Baylor Res Inst | Anticorpos anti-cd40 e seus usos |
CA2754743C (en) | 2009-03-10 | 2020-08-25 | Baylor Research Institute | Antigen presenting cell targeted anti-viral vaccines |
US20120141501A1 (en) * | 2009-05-29 | 2012-06-07 | Forerunner Pharma Research Co. Ltd | Pharmaceutical Composition Containing Antagonist of EGF Family Ligand as Component |
IT1397083B1 (it) * | 2009-12-04 | 2012-12-28 | Biouniversa Srl | Marcatore biochimico serico |
US11536713B2 (en) | 2009-12-25 | 2022-12-27 | Chugai Seiyaku Kabushiki Kaisha | Method for searching and screening for target of anti-cancer agent using non-human animal model having NOG established cancer cell line transplanted therein |
CA3014767C (en) | 2010-02-24 | 2023-08-29 | Immunogen, Inc. | Folate receptor 1 antibodies and immunoconjugates and uses thereof |
JP5858984B2 (ja) * | 2010-04-18 | 2016-02-10 | イェダ リサーチ アンド デベロップメント カンパニー リミテッド | ErbB/ErbBリガンドに関連する疾患を治療するための分子及びその分子を使用する方法 |
JP6230789B2 (ja) | 2010-10-06 | 2017-11-15 | 中外製薬株式会社 | 癌幹細胞集団及びその作製方法 |
US9309322B2 (en) | 2010-11-12 | 2016-04-12 | Scott & White Healthcare (Swh) | Antibodies to tumor endothelial marker 8 |
PL2663579T3 (pl) | 2011-01-14 | 2017-09-29 | The Regents Of The University Of California | Przeciwciała terapeutyczne przeciwko białku receptorowemu ror 1 oraz sposoby ich stosowania |
LT2694106T (lt) | 2011-04-01 | 2018-04-25 | Immunogen, Inc. | Folr1 vėžio terapijos veiksmingumo didinimo būdai |
AR085484A1 (es) | 2011-04-06 | 2013-10-02 | Lilly Co Eli | ANTICUERPOS QUE SE UNEN A TGF-a Y EPIREGULINA |
CN103827300A (zh) | 2011-06-30 | 2014-05-28 | 中外制药株式会社 | 异源二聚化多肽 |
JP6077997B2 (ja) | 2011-09-07 | 2017-02-08 | 中外製薬株式会社 | 癌幹細胞の分離 |
JP6291254B2 (ja) * | 2011-10-28 | 2018-03-14 | 中外製薬株式会社 | 癌幹細胞特異的分子 |
TWI593705B (zh) * | 2011-12-28 | 2017-08-01 | Chugai Pharmaceutical Co Ltd | Humanized anti-epiregulin antibody and cancer therapeutic agent containing the antibody as an active ingredient |
US9163090B2 (en) * | 2012-05-07 | 2015-10-20 | Cellerant Therapeutics, Inc. | Antibodies specific for CLL-1 |
MX362514B (es) | 2012-08-31 | 2019-01-22 | Immunogen Inc | Kits y ensayos de diagnostico para la deteccion del receptor 1 de folato. |
KR102249779B1 (ko) | 2012-12-27 | 2021-05-07 | 추가이 세이야쿠 가부시키가이샤 | 헤테로이량화 폴리펩티드 |
US20140273031A1 (en) * | 2013-03-15 | 2014-09-18 | The Cleveland Clinic Foundation | In-vitro method for monoclonal antibody production |
ES2695166T3 (es) * | 2013-03-15 | 2019-01-02 | Intrinsic Lifesciences Llc | Anticuerpos antihepcidina y usos de los mismos |
US20160159919A1 (en) * | 2013-06-24 | 2016-06-09 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic Agent Comprising Humanized Anti-Epiregulin Antibody as Active Ingredient for Non-Small-Cell Lung Carcinoma Excluding Adenocarcinoma |
AU2014312086B2 (en) | 2013-08-30 | 2020-03-12 | Immunogen, Inc. | Antibodies and assays for detection of folate receptor 1 |
CA2936833A1 (en) | 2014-01-13 | 2015-07-16 | Baylor Research Institute | Novel vaccines against hpv and hpv-related diseases |
US20170008955A1 (en) * | 2014-02-03 | 2017-01-12 | Cnj Holdings, Inc. | Humanized beta-amyloid binding molecules and uses thereof |
US11286285B2 (en) | 2014-02-18 | 2022-03-29 | Savid Therapeutics Inc. | Modified biotin, streptavidin mutant, and usage of them |
ES2924071T3 (es) | 2015-09-02 | 2022-10-04 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | Anticuerpos específicos para inmunoglobulina de células T humanas y dominio ITIM (TIGIT) |
CA2994888A1 (en) | 2015-09-17 | 2017-03-23 | Immunogen, Inc. | Therapeutic combinations comprising anti-folr1 immunoconjugates |
JP7045069B2 (ja) | 2016-11-25 | 2022-03-31 | サヴィッド・セラピューティックス株式会社 | クリアリングエージェント |
WO2019048040A1 (en) * | 2017-09-06 | 2019-03-14 | Ganymed Pharmaceuticals Gmbh | ANTIBODIES USEFUL IN THE DIAGNOSIS OF CANCER |
US10610585B2 (en) | 2017-09-26 | 2020-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treating and preventing HIV |
EP4486771A1 (en) * | 2022-03-04 | 2025-01-08 | Yale University | Methods and compositions for treating and preventing fibrosis |
CN116041482B (zh) * | 2022-09-29 | 2024-05-03 | 江汉大学 | 一种结构肽段的cDNA、结构肽段和制备方法及应用 |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58201994A (ja) | 1982-05-21 | 1983-11-25 | Hideaki Hagiwara | 抗原特異的ヒト免疫グロブリンの生産方法 |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
US5190858A (en) | 1989-02-01 | 1993-03-02 | Oncogene Science, Inc. | Monoclonal antibodies directed to epitopes of human transforming growth factor--α and uses thereof |
DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
WO1992020791A1 (en) | 1990-07-10 | 1992-11-26 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
JP3540315B2 (ja) | 1991-09-23 | 2004-07-07 | メディカル リサーチ カウンシル | キメラ抗体の製造−組合せアプローチ |
AU3178993A (en) | 1991-11-25 | 1993-06-28 | Enzon, Inc. | Multivalent antigen-binding proteins |
WO1993011236A1 (en) | 1991-12-02 | 1993-06-10 | Medical Research Council | Production of anti-self antibodies from antibody segment repertoires and displayed on phage |
AU3328493A (en) | 1991-12-17 | 1993-07-19 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
JP3507073B2 (ja) | 1992-03-24 | 2004-03-15 | ケンブリッジ アンティボディー テクノロジー リミティド | 特異的結合対の成員の製造方法 |
ATE381614T1 (de) | 1992-07-24 | 2008-01-15 | Amgen Fremont Inc | Bildung von xenogenen antikörpern |
US5648267A (en) | 1992-11-13 | 1997-07-15 | Idec Pharmaceuticals Corporation | Impaired dominant selectable marker sequence and intronic insertion strategies for enhancement of expression of gene product and expression vector systems comprising same |
AU6819494A (en) | 1993-04-26 | 1994-11-21 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
EP0703242A1 (en) | 1993-06-04 | 1996-03-27 | Taisho Pharmaceutical Co. Ltd | Human-origin tumor cell proliferation inhibiting factor |
GB9313509D0 (en) | 1993-06-30 | 1993-08-11 | Medical Res Council | Chemisynthetic libraries |
JPH09506508A (ja) | 1993-12-03 | 1997-06-30 | メディカル リサーチ カウンシル | 組換え結合タンパク質およびペプチド |
WO1996002576A1 (fr) | 1994-07-13 | 1996-02-01 | Chugai Seiyaku Kabushiki Kaisha | Anticorps humain reconstitue contre l'interleukine-8 humaine |
ATE390933T1 (de) | 1995-04-27 | 2008-04-15 | Amgen Fremont Inc | Aus immunisierten xenomäusen stammende menschliche antikörper gegen il-8 |
AU2466895A (en) | 1995-04-28 | 1996-11-18 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
DK2180007T4 (da) | 1998-04-20 | 2017-11-27 | Roche Glycart Ag | Glycosyleringsteknik for antistoffer til forbedring af antistofafhængig cellecytotoxicitet |
EP2270148A3 (en) | 1999-04-09 | 2011-06-08 | Kyowa Hakko Kirin Co., Ltd. | Method for controlling the activity of immunologically functional molecule |
NZ531426A (en) | 1999-06-25 | 2005-10-28 | Genentech Inc | Method of treating cancer wherein the cancer expresses epidermal growth factor receptor comprising administration of humanized anti-ErbB2 antibodies |
US6949245B1 (en) | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
JP4290423B2 (ja) | 2000-10-06 | 2009-07-08 | 協和発酵キリン株式会社 | 抗体組成物を生産する細胞 |
CU22979A1 (es) | 2000-12-08 | 2004-09-09 | Centro Inmunologia Molecular | Combinación inmunoterapéutica para el tratamiento de tumores que sobre-expresan receptores con actividad quinasa en residuos de tirosina |
EP1383800A4 (en) | 2001-04-02 | 2004-09-22 | Idec Pharma Corp | RECOMBINANT ANTIBODIES CO-EXPRESSED WITH GNTIII |
EP1514928B1 (en) | 2002-06-05 | 2013-07-31 | Chugai Seiyaku Kabushiki Kaisha | Method for producing antibodies using baculoviruses |
EP1517921B1 (en) * | 2002-06-28 | 2006-06-07 | Domantis Limited | Dual specific ligands with increased serum half-life |
EP1587921B1 (en) | 2003-01-22 | 2010-07-28 | GlycArt Biotechnology AG | Fusion constructs and use of same to produce antibodies with increased fc receptor binding affinity and effector function |
MXPA05009751A (es) * | 2003-03-14 | 2005-10-26 | Taisho Pharmaceutical Co Ltd | Anticuerpo monoclonal e hibridoma que lo produce. |
US7195764B2 (en) * | 2003-04-14 | 2007-03-27 | Arius Research Inc. | Cancerous disease modifying antibodies |
WO2005068503A2 (en) | 2004-01-07 | 2005-07-28 | Chiron Corporation | M-csf-specific monoclonal antibody and uses thereof |
CA2555145A1 (en) * | 2004-02-06 | 2005-08-25 | Wyeth | Diagnosis and therapeutics for cancer |
US20090061485A1 (en) | 2004-12-22 | 2009-03-05 | Chugai Seiyaku Kabushiki Kaisha | Method of Producing an Antibody Using a Cell in Which the Function of Fucose Transporter Is Inhibited |
CN101365712A (zh) | 2005-01-11 | 2009-02-11 | 莫勒丘尔洛吉克斯有限公司 | Pan-HER拮抗剂及其使用方法 |
EP1925676A4 (en) | 2005-08-02 | 2010-11-10 | Eisai R&D Man Co Ltd | TEST METHOD FOR THE EFFECT OF A VASCULARIZATION INHIBITOR |
EP2070548B1 (en) | 2006-10-12 | 2017-01-18 | Chugai Seiyaku Kabushiki Kaisha | Diagnosis and treatment of cancer using anti-ereg antibody |
US20120141501A1 (en) | 2009-05-29 | 2012-06-07 | Forerunner Pharma Research Co. Ltd | Pharmaceutical Composition Containing Antagonist of EGF Family Ligand as Component |
GB0909904D0 (en) | 2009-06-09 | 2009-07-22 | Affitech As | Product |
GB0909906D0 (en) | 2009-06-09 | 2009-07-22 | Affitech As | Antibodies |
TWI593705B (zh) | 2011-12-28 | 2017-08-01 | Chugai Pharmaceutical Co Ltd | Humanized anti-epiregulin antibody and cancer therapeutic agent containing the antibody as an active ingredient |
-
2007
- 2007-10-12 EP EP07829724.9A patent/EP2070548B1/en active Active
- 2007-10-12 JP JP2008539791A patent/JP5687822B2/ja active Active
- 2007-10-12 MX MX2009003738A patent/MX2009003738A/es active IP Right Grant
- 2007-10-12 UA UAA200904419A patent/UA106194C2/ru unknown
- 2007-10-12 KR KR1020097008620A patent/KR101493779B1/ko not_active IP Right Cessation
- 2007-10-12 AU AU2007312367A patent/AU2007312367B2/en not_active Ceased
- 2007-10-12 NZ NZ576855A patent/NZ576855A/xx not_active IP Right Cessation
- 2007-10-12 BR BRPI0719202-9A patent/BRPI0719202A2/pt not_active IP Right Cessation
- 2007-10-12 WO PCT/JP2007/069988 patent/WO2008047723A1/ja active Application Filing
- 2007-10-12 CN CN2013103003558A patent/CN103396486A/zh active Pending
- 2007-10-12 CN CN200780045915.2A patent/CN101594883B/zh not_active Expired - Fee Related
- 2007-10-12 CA CA2665528A patent/CA2665528C/en not_active Expired - Fee Related
- 2007-10-12 MY MYPI20091462A patent/MY162056A/en unknown
- 2007-10-12 US US12/444,916 patent/US9017684B2/en active Active
- 2007-10-12 RU RU2009117669/15A patent/RU2537245C2/ru not_active IP Right Cessation
- 2007-10-12 NZ NZ601022A patent/NZ601022A/en not_active IP Right Cessation
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2009
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2013
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2014
- 2014-10-03 JP JP2014204708A patent/JP5992480B2/ja active Active
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Also Published As
Publication number | Publication date |
---|---|
JP5992480B2 (ja) | 2016-09-14 |
JP2015091796A (ja) | 2015-05-14 |
IL197914A (en) | 2014-07-31 |
CA2665528C (en) | 2018-01-23 |
CN101594883A (zh) | 2009-12-02 |
MY162056A (en) | 2017-05-31 |
JPWO2008047723A1 (ja) | 2010-02-25 |
KR20090079214A (ko) | 2009-07-21 |
EP2070548A4 (en) | 2010-09-01 |
JP5687822B2 (ja) | 2015-03-25 |
EP2070548B1 (en) | 2017-01-18 |
EP2070548A1 (en) | 2009-06-17 |
KR101493779B1 (ko) | 2015-02-16 |
NZ601022A (en) | 2014-09-26 |
UA106194C2 (ru) | 2014-08-11 |
RU2014141151A3 (ru) | 2018-07-18 |
CN103396486A (zh) | 2013-11-20 |
RU2537245C2 (ru) | 2014-12-27 |
IL225386A0 (en) | 2013-06-27 |
US9017684B2 (en) | 2015-04-28 |
WO2008047723A1 (en) | 2008-04-24 |
CN101594883B (zh) | 2018-04-10 |
BRPI0719202A2 (pt) | 2015-06-16 |
AU2007312367A1 (en) | 2008-04-24 |
MX2009003738A (es) | 2009-07-17 |
AU2007312367B2 (en) | 2012-09-06 |
US20090324491A1 (en) | 2009-12-31 |
RU2009117669A (ru) | 2010-11-20 |
NZ576855A (en) | 2012-08-31 |
CA2665528A1 (en) | 2008-04-24 |
RU2014141151A (ru) | 2016-05-10 |
IL197914A0 (en) | 2011-08-01 |
IL225386A (en) | 2014-07-31 |
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