NO20025253D0 - Antistoff selektivt for en tumornekrosefaktor-relatert apoptose-induserende ligand reseptor og anvendelser derav - Google Patents
Antistoff selektivt for en tumornekrosefaktor-relatert apoptose-induserende ligand reseptor og anvendelser deravInfo
- Publication number
- NO20025253D0 NO20025253D0 NO20025253A NO20025253A NO20025253D0 NO 20025253 D0 NO20025253 D0 NO 20025253D0 NO 20025253 A NO20025253 A NO 20025253A NO 20025253 A NO20025253 A NO 20025253A NO 20025253 D0 NO20025253 D0 NO 20025253D0
- Authority
- NO
- Norway
- Prior art keywords
- necrosis factor
- tumor necrosis
- ligand receptor
- inducing ligand
- related apoptosis
- Prior art date
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20134400P | 2000-05-02 | 2000-05-02 | |
PCT/US2001/014151 WO2001083560A1 (en) | 2000-05-02 | 2001-05-02 | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20025253D0 true NO20025253D0 (no) | 2002-11-01 |
NO20025253L NO20025253L (no) | 2002-12-18 |
NO329843B1 NO329843B1 (no) | 2011-01-10 |
Family
ID=22745456
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20025253A NO329843B1 (no) | 2000-05-02 | 2002-11-01 | Renset antistoff samt anvendelse derav, in-vitro-metode, preparat og kommersielt sett |
NO20054145A NO338228B1 (no) | 2000-05-02 | 2005-09-06 | Fremgangsmåte for fremstilling av et antistoff |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20054145A NO338228B1 (no) | 2000-05-02 | 2005-09-06 | Fremgangsmåte for fremstilling av et antistoff |
Country Status (28)
Country | Link |
---|---|
US (6) | US7244429B2 (no) |
EP (4) | EP2065400B1 (no) |
JP (4) | JP4156238B2 (no) |
KR (2) | KR100817967B1 (no) |
CN (2) | CN101585881B (no) |
AT (1) | ATE426615T1 (no) |
AU (2) | AU2001259366B2 (no) |
BG (3) | BG65929B1 (no) |
BR (1) | BR0110547A (no) |
CA (1) | CA2407965C (no) |
CY (1) | CY1109179T1 (no) |
CZ (2) | CZ304614B6 (no) |
DE (1) | DE60138097D1 (no) |
DK (1) | DK1287035T3 (no) |
EE (1) | EE05548B1 (no) |
ES (1) | ES2323448T3 (no) |
HK (3) | HK1050372A1 (no) |
HU (2) | HU230399B1 (no) |
IL (1) | IL152605A0 (no) |
MX (1) | MXPA02010823A (no) |
NO (2) | NO329843B1 (no) |
NZ (1) | NZ522881A (no) |
PL (1) | PL211733B1 (no) |
PT (1) | PT1287035E (no) |
RU (1) | RU2298013C2 (no) |
TW (1) | TWI318983B (no) |
WO (1) | WO2001083560A1 (no) |
ZA (1) | ZA200209230B (no) |
Families Citing this family (84)
Publication number | Priority date | Publication date | Assignee | Title |
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US7528239B1 (en) | 1997-02-13 | 2009-05-05 | Immunex Corporation | Receptor that binds trail |
US6872568B1 (en) | 1997-03-17 | 2005-03-29 | Human Genome Sciences, Inc. | Death domain containing receptor 5 antibodies |
ES2281126T3 (es) | 1997-03-17 | 2007-09-16 | Human Genome Sciences, Inc. | Receptor 5 que contiene un dominio de muerte. |
CA2369371A1 (en) * | 1999-05-04 | 2000-11-09 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
US7279160B2 (en) | 2000-05-02 | 2007-10-09 | The Uab Research Foundation | Combinations of DR5 antibodies and other therapeutic agents |
US7476383B2 (en) | 2000-05-02 | 2009-01-13 | The Uab Research Foundation | Antibody selective for DR4 and uses thereof |
TWI318983B (en) * | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
US20030228309A1 (en) * | 2000-11-08 | 2003-12-11 | Theodora Salcedo | Antibodies that immunospecifically bind to TRAIL receptors |
US20060062786A1 (en) * | 2000-11-08 | 2006-03-23 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US8071740B2 (en) | 2000-11-17 | 2011-12-06 | Vascular Biogenics Ltd. | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis |
AU2003222427B8 (en) | 2000-11-17 | 2010-04-29 | Vascular Biogenics Ltd. | Promoters exhibiting endothelial cell specificity and methods of using same |
US7115717B2 (en) | 2001-05-18 | 2006-10-03 | Kirin Beer Kabushiki Kaisha | Anti-TRAIL-R antibodies |
US7348003B2 (en) | 2001-05-25 | 2008-03-25 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors |
US20050129616A1 (en) * | 2001-05-25 | 2005-06-16 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US20090226429A1 (en) * | 2001-05-25 | 2009-09-10 | Human Genome Sciences, Inc. | Antibodies That Immunospecifically Bind to TRAIL Receptors |
NZ529359A (en) | 2001-05-25 | 2007-04-27 | Human Genome Sciences Inc | Antibodies that immunospecifically bind to a TR4 polypeptide or polypeptide fragment or variant of TR4 and their use in a medicament for treating cancer |
US20050214209A1 (en) * | 2001-05-25 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US7361341B2 (en) | 2001-05-25 | 2008-04-22 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to trail receptors |
CA2463816C (en) | 2001-10-19 | 2014-07-08 | Vascular Biogenics Ltd. | Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy |
ES2357225T3 (es) * | 2001-11-01 | 2011-04-20 | Uab Research Foundation | Combinaciones de anticuerpos anti-dr5 y anticuerpos anti-dr4 y otros agentes terapéuticos. |
BRPI0213846B8 (pt) * | 2001-11-01 | 2021-05-25 | Uab Research Foundation | composição que compreende um anticorpo que liga especificamente uma dr5 do receptor de trail e um ou mais agentes terapêuticos |
KR20040070254A (ko) * | 2001-12-20 | 2004-08-06 | íŽëšŒ ê²ë ì¬ìŽìžììŠ, ìžìœí¬ë ìŽí°ë | ïœïœïœïœ ìì©ì²Žì ë©Žìí¹ìŽì ìŒë¡ ê²°í©íë í첎 |
US20050069549A1 (en) | 2002-01-14 | 2005-03-31 | William Herman | Targeted ligands |
DE10210427A1 (de) * | 2002-03-09 | 2003-10-09 | Hans Konrad Mueller-Hermelink | Humaner monoklonaler Antikörper |
US7772372B2 (en) | 2002-07-04 | 2010-08-10 | Patrys Limited | Neoplasm specific antibodies and uses thereof |
AU2008201431B2 (en) * | 2002-11-27 | 2011-11-24 | Irm, Llc | Methods and compositions for inducing Apoptosis in cancer cells |
KR100915257B1 (ko) * | 2002-11-27 | 2009-09-03 | ììŽìì ìììš | ëšìŒíŽë¡ í-ïœïœïŒ íšë¥ì í첎, ê·ž í첎륌 ë°ííë ëšëŠ¬ë ìží¬, ê·ž í첎륌 í¬íšíë ì ìœ ì¡°ì±ë¬Œ ë° ê·ž í첎륌 ì¬ì©íë ë°©ë² |
DE10311248A1 (de) | 2003-03-14 | 2004-09-30 | MÌller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper |
DE10353175A1 (de) | 2003-11-14 | 2005-06-16 | MÌller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper mit fettsenkender Wirkung |
EP1531162A1 (en) | 2003-11-14 | 2005-05-18 | Heinz Vollmers | Adenocarcinoma specific antibody SAM-6, and uses thereof |
AU2005227322A1 (en) * | 2004-03-23 | 2005-10-06 | Biogen Idec Ma Inc. | Receptor coupling agents and therapeutic uses thereof |
CN100427505C (zh) * | 2004-08-19 | 2008-10-22 | äžåœå»åŠç§åŠé¢åºç¡å»åŠç 究æ | æ人è¿ç€åæ»å åçžå ³å亡诱富é äœçåäœdr5åå éæäœïŒad5-10ïŒåå ¶å¶æ³äžçšé |
CN102977205A (zh) * | 2004-12-13 | 2013-03-20 | èµåŒé柳倧å©äº(Vic)ç§äººæéå ¬åž | 骚ä¿æ€çŽ ååŒèçœ |
AU2006210838B2 (en) | 2005-02-02 | 2011-10-20 | The Uab Research Foundation | Agents and methods related to reducing resistance to apoptosis-inducing death receptor agonists |
US8029783B2 (en) * | 2005-02-02 | 2011-10-04 | Genentech, Inc. | DR5 antibodies and articles of manufacture containing same |
JP5004154B2 (ja) * | 2005-04-06 | 2012-08-22 | äžè¬è²¡å£æ³äººååŠåè¡æž çæ³ç 究æ | çµæãæãããªãã¹ç¥çµæ¯çŽ æäœ |
US8901281B2 (en) | 2005-06-17 | 2014-12-02 | Merck Sharp & Dohme Corp. | ILT3 binding molecules and uses therefor |
PE20071101A1 (es) * | 2005-08-31 | 2007-12-21 | Amgen Inc | Polipeptidos y anticuerpos |
CN101300273B (zh) * | 2005-08-31 | 2013-05-22 | å®å§æ ¹æéå ¬åž | Trailåäœ2å€èœåæäœ |
US8168181B2 (en) | 2006-02-13 | 2012-05-01 | Alethia Biotherapeutics, Inc. | Methods of impairing osteoclast differentiation using antibodies that bind siglec-15 |
KR20090031359A (ko) | 2006-05-16 | 2009-03-25 | êµì í«êŒ¬ Ʞ늰 ê°ë¶ìí€ê°ìŽì€ | ëšë°±ì§ì ê³ ë¶ë¹ ìì° ë°©ë² |
WO2008094176A2 (en) * | 2006-06-19 | 2008-08-07 | Tolerx, Inc. | Ilt3 binding molecules and uses therefor |
KR100847010B1 (ko) * | 2006-07-05 | 2008-07-17 | ì죌ëíêµì°ííë ¥ëš | ìží¬ì¬ë©ž ìì©ì²Ž 5 (ïœïœ5)ì í¹ìŽì ìŒë¡ ê²°í©íë í첎 ë°ìŽë¥Œ í¬íšíë ì ìë°© ëë ì¹ë£ì© ì¡°ì±ë¬Œ |
KR100804126B1 (ko) | 2007-02-09 | 2008-02-19 | ì죌ëíêµì°ííë ¥ëš | ì¢ ì êŽŽì¬ ìžìâêŽë š ìží¬ì¬ë©žâì ë 늬ê°ëì ìì©ì²Žìí¹ìŽì ìŒë¡ ê²°í©íë 1ê°ì ìžê° ëšìŒíŽë¡ í첎 ë° ê·žìíìê²°í© ëšíž |
WO2008154439A1 (en) * | 2007-06-08 | 2008-12-18 | Irm Llc | Methods and compositions for inducing apoptosis in cancer cells |
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