Nothing Special   »   [go: up one dir, main page]

NO20014363L - 4-okso-4,7-dihydro-tieno[2,3-b]pyridin-5-karboksamider som antivirale midler - Google Patents

4-okso-4,7-dihydro-tieno[2,3-b]pyridin-5-karboksamider som antivirale midler

Info

Publication number
NO20014363L
NO20014363L NO20014363A NO20014363A NO20014363L NO 20014363 L NO20014363 L NO 20014363L NO 20014363 A NO20014363 A NO 20014363A NO 20014363 A NO20014363 A NO 20014363A NO 20014363 L NO20014363 L NO 20014363L
Authority
NO
Norway
Prior art keywords
antivirals
carboxamides
thieno
dihydro
oxo
Prior art date
Application number
NO20014363A
Other languages
English (en)
Other versions
NO20014363D0 (no
Inventor
Mark E Schnute
Michele M Cudahy
Allen Scott
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO20014363D0 publication Critical patent/NO20014363D0/no
Publication of NO20014363L publication Critical patent/NO20014363L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
NO20014363A 1999-03-09 2001-09-07 4-okso-4,7-dihydro-tieno[2,3-b]pyridin-5-karboksamider som antivirale midler NO20014363L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12366099P 1999-03-09 1999-03-09
PCT/US2000/005937 WO2000053610A2 (en) 1999-03-09 2000-03-07 4-OXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS

Publications (2)

Publication Number Publication Date
NO20014363D0 NO20014363D0 (no) 2001-09-07
NO20014363L true NO20014363L (no) 2001-11-08

Family

ID=22410054

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014363A NO20014363L (no) 1999-03-09 2001-09-07 4-okso-4,7-dihydro-tieno[2,3-b]pyridin-5-karboksamider som antivirale midler

Country Status (25)

Country Link
US (2) US6239142B1 (no)
EP (1) EP1159279B1 (no)
JP (1) JP2002539130A (no)
KR (1) KR20010102543A (no)
CN (1) CN1347417A (no)
AT (1) ATE226208T1 (no)
AU (1) AU759875B2 (no)
BR (1) BR0008804A (no)
CA (1) CA2366609A1 (no)
CZ (1) CZ20013028A3 (no)
DE (1) DE60000611T2 (no)
DK (1) DK1159279T3 (no)
EA (1) EA003607B1 (no)
ES (1) ES2184705T3 (no)
HK (1) HK1045518A1 (no)
HU (1) HUP0200324A3 (no)
IL (1) IL145005A0 (no)
NO (1) NO20014363L (no)
NZ (1) NZ513758A (no)
PL (1) PL350651A1 (no)
PT (1) PT1159279E (no)
SK (1) SK12582001A3 (no)
TW (1) TWI222451B (no)
WO (1) WO2000053610A2 (no)
ZA (1) ZA200107255B (no)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6559145B2 (en) 2000-07-12 2003-05-06 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US6730682B2 (en) 2000-07-12 2004-05-04 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US6562822B2 (en) 2000-07-12 2003-05-13 Pharmacia & Upjohn Company Heterocyle carboxamides as antiviral agents
US8101629B2 (en) 2001-08-13 2012-01-24 Janssen Pharmaceutica N.V. Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
JO3429B1 (ar) 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
US7638522B2 (en) 2001-08-13 2009-12-29 Janssen Pharmaceutica N.V. Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile
WO2003020728A1 (en) * 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
MXPA04001797A (es) * 2001-08-30 2004-07-08 Pharmacia & Upjhon Company 4-tioxo-4,7-dihidro-teno[2,3-b]piridin-5-carboxamidas como agentes antivirales.
EP1467978A4 (en) * 2001-12-20 2005-11-02 Osi Pharm Inc "COMPOUNDS THAT CONTAIN VACCINATES DRUG LIPASE, THEIR SYNTHESIS AND USE"
AR038117A1 (es) * 2002-01-14 2004-12-29 Upjohn Co Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
AR038118A1 (es) * 2002-01-14 2004-12-29 Upjohn Co Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
AR038294A1 (es) 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
WO2003089437A1 (en) * 2002-04-22 2003-10-30 Pharmacia & Upjohn Company A trifluoroacetic acid process to prepare [2,3-b]pyridine intermediates
US7399856B2 (en) 2002-08-09 2008-07-15 Janssen Pharmaceutica N.V. Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-2pyrimidinyl]amino]benzonitrile
US20040176366A1 (en) * 2002-08-30 2004-09-09 Wathen Michael W Method of preventing or treating atherosclerosis or restenosis
WO2004019939A1 (en) * 2002-08-30 2004-03-11 Pharmacia & Upjohn Company Method of preventing or treating atherosclerosis or restenosis
WO2004019932A1 (en) * 2002-08-30 2004-03-11 Pharmacia & Upjohn Company Method of preventing or treating atherosclerosis or restenosis
AU2003262910A1 (en) * 2002-08-30 2004-03-19 Pharmacia And Upjohn Company Method of preventing or treating atherosclerosis or restenosis
US6831081B2 (en) * 2002-09-04 2004-12-14 Pharmacia & Upjohn 4-Oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents
US20050049245A1 (en) * 2002-09-04 2005-03-03 Schnute Mark E. Heteroaryl-ethanolamine derivatives as antiviral agents
US20040110787A1 (en) * 2002-09-04 2004-06-10 Schnute Mark E. Heteroaryl-ethanolamine derivatives as antiviral agents
WO2004106345A2 (en) * 2002-09-04 2004-12-09 Pharmacia & Upjohn Company Heteroaryl-ethanolamine derivatives as antiviral agents
WO2005003140A1 (en) * 2003-07-02 2005-01-13 Pharmacia & Upjohn Company Llc 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents
JP2007532615A (ja) * 2004-04-13 2007-11-15 アステックス、セラピューティックス、リミテッド 医薬化合物
SE0401578D0 (sv) 2004-06-18 2004-06-18 Active Biotech Ab Novel compounds
WO2006093518A2 (en) * 2004-06-25 2006-09-08 Apath, Llc Thienyl compounds for treating virus-related conditions
EP3181568A1 (en) 2009-02-27 2017-06-21 Siga Technologies, Inc. Thienopyridine derivatives for the treatment and prevention of dengue virus infections
BR112018016689A2 (pt) 2016-02-16 2019-02-12 Univ Vanderbilt moduladores alostéricos positivos do receptor muscarínico de acetilcolina m1
US10899759B2 (en) 2016-09-30 2021-01-26 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor M1
TWI838401B (zh) 2018-09-12 2024-04-11 瑞士商諾華公司 抗病毒性吡啶并吡𠯤二酮化合物
AU2020353055B2 (en) 2019-09-26 2024-03-07 Gilead Sciences, Inc. Antiviral pyrazolopyridinone compounds
CN115073489B (zh) * 2021-03-15 2023-11-28 同济大学 一种噻吩骈吡啶酮类化合物、制备方法及一种抗真菌药物

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5268193A (en) 1975-11-28 1977-06-06 Sumitomo Chem Co Ltd Synthesis of novel cephalosporin derivatives
US4145418A (en) 1976-01-06 1979-03-20 Takeda Chemical Industries, Ltd. Thienopyridine substituted cephalosporins
US4568649A (en) 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4767766A (en) 1987-01-30 1988-08-30 Merck & Co., Inc. Derivatives of 3-hydroxyazabenzo(B)thiophene useful as 5-lipoxygenase inhibitors
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
US4992478A (en) 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US4959363A (en) 1989-06-23 1990-09-25 Sterling Drug Inc. Quinolonecarboxamide compounds, their preparation and use as antivirals.
CA2036618C (en) * 1990-02-22 2002-10-29 Akira Morimoto Fused thiophene derivatives, their production and use
WO1992003427A1 (en) 1990-08-17 1992-03-05 Yoshitomi Pharmaceutical Industries, Ltd. Ketone compound and remedy for osteoporosis
US5219864A (en) 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
DE4227747A1 (de) 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
JPH0776586A (ja) 1993-07-16 1995-03-20 Yoshitomi Pharmaceut Ind Ltd ピリジン化合物
TW449600B (en) 1994-04-19 2001-08-11 Takeda Chemical Industries Ltd Condensed-ring thiophene derivatives, their production and use
AU4515896A (en) 1994-12-12 1996-07-03 Merck & Co., Inc. Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase
AU4515696A (en) 1994-12-12 1996-07-03 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
JPH08301849A (ja) 1995-05-01 1996-11-19 Takeda Chem Ind Ltd ヘテロ環化合物およびその製造法
JPH09208496A (ja) 1996-01-30 1997-08-12 Takeda Chem Ind Ltd Ｌｈ−ｒｈ拮抗物質含有組成物
CA2250908C (en) 1996-04-30 2012-03-13 Takeda Chemical Industries, Ltd. Combined use of gnrh agonist and antagonist
JP2002505660A (ja) 1996-09-10 2002-02-19 ファルマシア・アンド・アップジョン・カンパニー 抗ウィルス剤としての８―ヒドロキシ―７―置換キノリン
CA2333770A1 (en) 1998-06-04 1999-12-09 Abbott Laboratories Cell adhesion-inhibiting antinflammatory compounds

Also Published As

Publication number Publication date
TWI222451B (en) 2004-10-21
HUP0200324A2 (en) 2002-06-29
PT1159279E (pt) 2003-02-28
ZA200107255B (en) 2002-12-02
WO2000053610A3 (en) 2001-01-25
KR20010102543A (ko) 2001-11-15
EA200100955A1 (ru) 2002-02-28
AU3516200A (en) 2000-09-28
ATE226208T1 (de) 2002-11-15
ES2184705T3 (es) 2003-04-16
CZ20013028A3 (cs) 2002-03-13
PL350651A1 (en) 2003-01-27
BR0008804A (pt) 2002-04-16
EA003607B1 (ru) 2003-06-26
US6495683B2 (en) 2002-12-17
EP1159279A2 (en) 2001-12-05
US6239142B1 (en) 2001-05-29
NZ513758A (en) 2001-09-28
DE60000611T2 (de) 2003-06-26
WO2000053610A2 (en) 2000-09-14
HUP0200324A3 (en) 2003-07-28
EP1159279B1 (en) 2002-10-16
DK1159279T3 (da) 2003-02-17
NO20014363D0 (no) 2001-09-07
DE60000611D1 (en) 2002-11-21
JP2002539130A (ja) 2002-11-19
IL145005A0 (en) 2002-06-30
HK1045518A1 (zh) 2002-11-29
AU759875B2 (en) 2003-05-01
CN1347417A (zh) 2002-05-01
US20020006937A1 (en) 2002-01-17
CA2366609A1 (en) 2000-09-14
SK12582001A3 (sk) 2002-02-05

Similar Documents

Publication Publication Date Title
DK1159279T3 (da) 4-Oxo-4,7-dihydro-thieno[2,3-b]pyridin-5-carboxamider som antivirale midler
AP1753A (en) Thiophene derivatives as antiviral agents for flavvivirus infection
WO2001019829A3 (en) Pyrazolopyrimidines as therapeutic agents
WO2001066534A3 (en) Cyclic and bicyclic diamino histamine-3 receptor antagonists
WO2002057252A3 (en) Heterocyclic sulfonamide inhibitors of beta amyloid production
SE9900100D0 (sv) New compounds
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
SE9903760D0 (sv) New compounds
AU6607901A (en) Azaindole derivatives, process for their preparation, and their use as antitumoragents
YU69902A (sh) Novi derivati piperazina
MXPA02003977A (es) Inhibidores de adhesion de celula mediada por al°2.
DE60026404D1 (de) Verfahren zur Herstellung von Benzothiophen-Derivaten
EA200100994A1 (ru) 1-АМИНОТРИАЗОЛО[4,3-а]ХИНАЗОЛИН-5-ОНЫ И/ИЛИ -5-ТИОНЫ, ИНГИБИРУЮЩИЕ ФОСФОДИЭСТЕРАЗУ-IV
MXPA04006041A (es) Antivirales de piridoquinoxalina.
PT992509E (pt) Novos derivados macrolidos
EE200000472A (et) Kasvajavastased toimeained
WO2003008365A3 (en) Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents
WO2003059878A3 (en) Thieno (3, 2-b) pyridones as antiviral compounds
AU6220300A (en) Benzofurylpiperazine serotonin agonists
WO2003059911A3 (en) 4-OXO-4, 7-DIHYDROFURO[2,3-b]PYRIDINE-5-CARBOXAMIDE ANTIVIRAL AGENTS
MX9804828A (es) Benzotiazolona etanaminas biologicamente activas.
BR0211214A (pt) 4-tioxo-4,7-dihidro-tieno [2,3-b]piridina-5-carboxamidas como agentes antivirais
TWI255813B (en) Compounds for use as alphavbeta3 receptor antagonists
MXPA03012039A (es) Derivados de benzo [g]quinolina para tratar glaucoma y miopia.
GEP20063758B (en) Benzothia(Dia)Zine Derivatives and Method for Their Use as AMPA Modulators

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application