NO20013731L - Diazabicykliske derivater som nikotinacetylkolinreseptorligander - Google Patents

Diazabicykliske derivater som nikotinacetylkolinreseptorligander

Info

Publication number: NO20013731L
Authority: NO; Norway
Prior art keywords: group; covalent bond; acetylcholine receptor; receptor ligands; nicotinic acetylcholine
Prior art date: 1999-01-29

Application number

NO20013731A

Other languages

English (en)

Norwegian (no)

Other versions

NO20013731D0 (no

Inventor

William H Bunnelle

Daniela Barlocco Cristina

Jerome F Daanen

Michael J Dart

Michael D Meyer

Keith B Ryther

Michael R Schrimpf

Kevin B Sippy

Richard B Toupence

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-29

Filing date

2001-07-30

Publication date

2001-09-18

2001-07-30 Application filed by Abbott Lab filed Critical Abbott Lab

2001-07-30 Publication of NO20013731D0 publication Critical patent/NO20013731D0/no

2001-09-18 Publication of NO20013731L publication Critical patent/NO20013731L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/20—Hypnotics; Sedatives
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Rheumatology (AREA)
Gynecology & Obstetrics (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO20013731A 1999-01-29 2001-07-30 Diazabicykliske derivater som nikotinacetylkolinreseptorligander NO20013731L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US23983899A	1999-01-29	1999-01-29
PCT/US2000/001620 WO2000044755A1 (en)	1999-01-29	2000-01-25	Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands

Publications (2)

Publication Number	Publication Date
NO20013731D0 NO20013731D0 (no)	2001-07-30
NO20013731L true NO20013731L (no)	2001-09-18

Family

ID=22903947

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20013731A NO20013731L (no)	1999-01-29	2001-07-30	Diazabicykliske derivater som nikotinacetylkolinreseptorligander

Country Status (26)

Country	Link
EP (2)	EP1359152B1 (pt)
JP (1)	JP4676062B2 (pt)
KR (1)	KR20010101725A (pt)
CN (2)	CN1345320A (pt)
AR (1)	AR034538A1 (pt)
AT (2)	ATE253067T1 (pt)
AU (1)	AU773795B2 (pt)
BG (1)	BG105836A (pt)
BR (1)	BR0007664A (pt)
CA (1)	CA2361525C (pt)
CO (1)	CO5150231A1 (pt)
CZ (1)	CZ20012716A3 (pt)
DE (2)	DE60038823D1 (pt)
DK (1)	DK1147112T3 (pt)
ES (2)	ES2305373T3 (pt)
HK (1)	HK1043116B (pt)
HU (1)	HUP0200332A3 (pt)
IL (1)	IL144340A0 (pt)
NO (1)	NO20013731L (pt)
NZ (1)	NZ512884A (pt)
PT (1)	PT1147112E (pt)
SK (1)	SK10692001A3 (pt)
TR (1)	TR200102162T2 (pt)
TW (1)	TW200300021A (pt)
WO (1)	WO2000044755A1 (pt)
ZA (1)	ZA200105835B (pt)

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2000
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- 2000-01-25 DE DE60038823T patent/DE60038823D1/de not_active Expired - Lifetime
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Also Published As

Publication number	Publication date
NO20013731D0 (no)	2001-07-30
BG105836A (en)	2002-03-29
EP1359152A3 (en)	2003-12-17
CN1345320A (zh)	2002-04-17
HK1043116A1 (en)	2002-09-06
DE60006213T2 (de)	2004-07-29
TW200300021A (en)	2003-05-01
AR034538A1 (es)	2004-03-03
HUP0200332A2 (en)	2002-06-29
ES2209825T3 (es)	2004-07-01
WO2000044755A1 (en)	2000-08-03
NZ512884A (en)	2004-03-26
HUP0200332A3 (en)	2002-09-30
JP2002535409A (ja)	2002-10-22
CA2361525C (en)	2009-12-08
ATE253067T1 (de)	2003-11-15
KR20010101725A (ko)	2001-11-14
EP1147112B1 (en)	2003-10-29
TR200102162T2 (tr)	2001-12-21
JP4676062B2 (ja)	2011-04-27
EP1147112A1 (en)	2001-10-24
SK10692001A3 (sk)	2002-01-07
IL144340A0 (en)	2002-05-23
CO5150231A1 (es)	2002-04-29
DE60006213D1 (de)	2003-12-04
EP1359152B1 (en)	2008-05-07
DE60038823D1 (de)	2008-06-19
HK1043116B (zh)	2004-10-15
EP1359152A2 (en)	2003-11-05
CA2361525A1 (en)	2000-08-03
AU773795B2 (en)	2004-06-03
DK1147112T3 (da)	2004-02-23
PT1147112E (pt)	2004-03-31
CZ20012716A3 (cs)	2001-11-14
ES2305373T3 (es)	2008-11-01
CN1636996A (zh)	2005-07-13
ATE394401T1 (de)	2008-05-15
AU2856900A (en)	2000-08-18
BR0007664A (pt)	2002-05-07
ZA200105835B (en)	2002-10-16

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