NO20005196L - Substituerte pyrrolidinhydroksamat-metallproteaseinhibitorer - Google Patents
Substituerte pyrrolidinhydroksamat-metallproteaseinhibitorerInfo
- Publication number
- NO20005196L NO20005196L NO20005196A NO20005196A NO20005196L NO 20005196 L NO20005196 L NO 20005196L NO 20005196 A NO20005196 A NO 20005196A NO 20005196 A NO20005196 A NO 20005196A NO 20005196 L NO20005196 L NO 20005196L
- Authority
- NO
- Norway
- Prior art keywords
- protease inhibitors
- substituted pyrrolidine
- metal protease
- hydroxamate
- pyrrolidine hydroxamate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8166798P | 1998-04-14 | 1998-04-14 | |
| PCT/US1999/007826 WO1999052868A1 (en) | 1998-04-14 | 1999-04-09 | Substituted pyrrolidine hydroxamate metalloprotease inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20005196D0 NO20005196D0 (no) | 2000-10-16 |
| NO20005196L true NO20005196L (no) | 2000-12-14 |
Family
ID=22165611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005196A NO20005196L (no) | 1998-04-14 | 2000-10-16 | Substituerte pyrrolidinhydroksamat-metallproteaseinhibitorer |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6329418B1 (pt) |
| EP (1) | EP1073635A1 (pt) |
| JP (1) | JP2002511448A (pt) |
| KR (1) | KR100400507B1 (pt) |
| CN (1) | CN1297436A (pt) |
| AR (1) | AR029145A1 (pt) |
| AU (1) | AU753048B2 (pt) |
| BR (1) | BR9909620A (pt) |
| CA (1) | CA2328211A1 (pt) |
| CO (1) | CO5011039A1 (pt) |
| HU (1) | HUP0102195A3 (pt) |
| ID (1) | ID26925A (pt) |
| IL (1) | IL138738A0 (pt) |
| NO (1) | NO20005196L (pt) |
| NZ (1) | NZ507076A (pt) |
| PE (1) | PE20000425A1 (pt) |
| PL (1) | PL343529A1 (pt) |
| SK (1) | SK15462000A3 (pt) |
| TR (1) | TR200002971T2 (pt) |
| WO (1) | WO1999052868A1 (pt) |
| ZA (1) | ZA200005047B (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6403632B1 (en) * | 2000-03-01 | 2002-06-11 | Bristol Myers Squibb Pharma Co | Lactam metalloprotease inhibitors |
| US7018988B2 (en) | 2000-03-27 | 2006-03-28 | Applied Research Systems Ars Holding N.V. | Pharmaceutically active pyrrolidine derivatives as Bax inhibitors |
| DE60120940T2 (de) | 2000-03-27 | 2007-01-25 | Applied Research Systems Ars Holding N.V. | Pyrrolidin-derivate verwendbar als bax-inhibitoren |
| US8283135B2 (en) | 2000-06-30 | 2012-10-09 | The Procter & Gamble Company | Oral care compositions containing combinations of anti-bacterial and host-response modulating agents |
| JP3983662B2 (ja) * | 2000-07-19 | 2007-09-26 | エフ．ホフマン−ラ ロシュ アーゲー | ピリミジン誘導体 |
| FR2819252A1 (fr) * | 2001-01-11 | 2002-07-12 | Servier Lab | Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| SE0100903D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
| SE0100902D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
| JP4350948B2 (ja) | 2001-03-20 | 2009-10-28 | ラボラトワール セローノ ソシエテ アノニム | オキシトシン調節活性を有するピロリジンエステル誘導体 |
| SE0103710D0 (sv) * | 2001-11-07 | 2001-11-07 | Astrazeneca Ab | Compounds |
| UA78058C2 (en) | 2002-07-05 | 2007-02-15 | Applied Research Systems | Pyrrolidine derivative as oxitocin antagonists |
| SE0202539D0 (sv) | 2002-08-27 | 2002-08-27 | Astrazeneca Ab | Compounds |
| GB0221246D0 (en) * | 2002-09-13 | 2002-10-23 | Astrazeneca Ab | Compounds |
| CN1294120C (zh) * | 2003-10-21 | 2007-01-10 | 山东大学 | 吡咯烷类基质金属蛋白酶抑制剂及其应用 |
| CA2554767A1 (en) * | 2004-02-26 | 2005-09-09 | Applied Research Systems Ars Holding N.V. | Method for preparing pyrrolidine oximes |
| US7648992B2 (en) | 2004-07-05 | 2010-01-19 | Astrazeneca Ab | Hydantoin derivatives for the treatment of obstructive airway diseases |
| SE0401762D0 (sv) * | 2004-07-05 | 2004-07-05 | Astrazeneca Ab | Novel compounds |
| WO2006038265A1 (ja) * | 2004-09-30 | 2006-04-13 | Yutaka Imauchi | 耳硬化症治療のための医薬組成物 |
| SE0403086D0 (sv) * | 2004-12-17 | 2004-12-17 | Astrazeneca Ab | Compounds |
| SE0403085D0 (sv) * | 2004-12-17 | 2004-12-17 | Astrazeneca Ab | Novel componds |
| TW200831488A (en) * | 2006-11-29 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
| CA2766696A1 (en) | 2009-06-24 | 2010-12-29 | Boehringer Ingelheim International Gmbh | New compounds, pharmaceutical composition and methods relating thereto |
| US8481731B2 (en) | 2009-06-24 | 2013-07-09 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical composition and methods relating thereto |
| EP2845850A1 (en) | 2013-09-10 | 2015-03-11 | ObsEva S.A. | Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists |
| EP2886107A1 (en) | 2013-12-17 | 2015-06-24 | ObsEva S.A. | Oral formulations of pyrrolydine derivatives |
| WO2016000920A1 (en) | 2014-07-02 | 2016-01-07 | ObsEva SA | Crystalline (3z,5s)-5-(hydroxymethyl)-1-[(2'-methyl-1,1'-biphenyl-4-yl)carbonyl]pyrrolidin-3-one o-methyloxime useful in methods of treating conditions related to the ot-r activity |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3380992A (en) * | 1965-06-14 | 1968-04-30 | Upjohn Co | Lincomycin derivatives and process for preparing same |
| US4377701A (en) * | 1981-09-21 | 1983-03-22 | E. R. Squibb & Sons, Inc. | 4-Methylene-1-[[(alranoyl or arylcarbonyl)mercapto]acyl]proline and pipecolic acid |
| US4743587A (en) | 1985-09-10 | 1988-05-10 | G. D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
| US4771038A (en) | 1986-01-21 | 1988-09-13 | Ici Americas Inc. | Hydroxamic acids |
| DK77487A (da) | 1986-03-11 | 1987-09-12 | Hoffmann La Roche | Hydroxylaminderivater |
| ZW23187A1 (en) | 1986-12-15 | 1988-06-29 | Hoffmann La Roche | Phosphinic acid derivatives |
| US5183900A (en) | 1990-11-21 | 1993-02-02 | Galardy Richard E | Matrix metalloprotease inhibitors |
| US5892112A (en) | 1990-11-21 | 1999-04-06 | Glycomed Incorporated | Process for preparing synthetic matrix metalloprotease inhibitors |
| GB9102635D0 (en) | 1991-02-07 | 1991-03-27 | British Bio Technology | Compounds |
| GB9107368D0 (en) | 1991-04-08 | 1991-05-22 | Smithkline Beecham Plc | Novel compounds |
| WO1992022523A2 (en) | 1991-06-14 | 1992-12-23 | Research Corporation Technologies, Inc. | Peptide derivatives of collagenase inhibitor |
| JPH05125029A (ja) | 1991-11-06 | 1993-05-21 | Yamanouchi Pharmaceut Co Ltd | 新規なアミド化合物又はその塩 |
| WO1993014112A1 (en) | 1992-01-15 | 1993-07-22 | Merck & Co., Inc. | Substituted phosphinic acid-containing peptidyl derivatives as antidegenerative agents |
| AU4267293A (en) | 1992-05-01 | 1993-11-29 | British Biotech Pharmaceuticals Limited | Use of MMP inhibitors |
| US5318964A (en) | 1992-06-11 | 1994-06-07 | Hoffmann-La Roche Inc. | Hydroxamic derivatives and pharmaceutical compositions |
| AU666727B2 (en) | 1992-06-25 | 1996-02-22 | F. Hoffmann-La Roche Ag | Hydroxamic acid derivatives |
| GB9215665D0 (en) | 1992-07-23 | 1992-09-09 | British Bio Technology | Compounds |
| GB9223904D0 (en) | 1992-11-13 | 1993-01-06 | British Bio Technology | Inhibition of cytokine production |
| US5506242A (en) | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
| US5455258A (en) | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| GB9308695D0 (en) | 1993-04-27 | 1993-06-09 | Celltech Ltd | Peptidyl derivatives |
| WO1994025434A1 (en) | 1993-04-27 | 1994-11-10 | Celltech Limited | Peptidyl derivatives as metalloproteinase inhibitors |
| WO1995004033A1 (en) | 1993-08-02 | 1995-02-09 | Celltech Limited | Succinamide derivatives, processes for their preparation and their use as gelatinase and collagenase inhibitors |
| GB9316162D0 (en) * | 1993-08-04 | 1993-09-22 | Zeneca Ltd | Fungicides |
| US5545735A (en) | 1993-10-04 | 1996-08-13 | Merck & Co., Inc. | Benzo-Fused Lactams promote release of growth hormone |
| US5470834A (en) | 1993-10-06 | 1995-11-28 | Florida State University | Sulfoximine and suldodiimine matrix metalloproteinase inhibitors |
| US5403952A (en) | 1993-10-08 | 1995-04-04 | Merck & Co., Inc. | Substituted cyclic derivatives as novel antidegenerative agents |
| UA48121C2 (uk) | 1993-11-04 | 2002-08-15 | Сінтекс (С.Ш.А.) Інк. | Інгібітори матричних металопротеаз і фармацетична композиція на їх основі |
| GB9323165D0 (en) | 1993-11-10 | 1994-01-05 | Chiros Ltd | Compounds |
| DE19581347T1 (de) | 1994-01-20 | 1996-12-05 | British Biotech Pharm | Metalloproteinase-Inhibitoren |
| GB9401129D0 (en) | 1994-01-21 | 1994-03-16 | British Bio Technology | Hydroxamic acid derivatives as metalloproteinase inhibitors |
| EP0740655B1 (en) | 1994-01-22 | 1999-10-20 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
| US5514716A (en) | 1994-02-25 | 1996-05-07 | Sterling Winthrop, Inc. | Hydroxamic acid and carboxylic acid derivatives, process for their preparation and use thereof |
| GB9404046D0 (en) | 1994-03-03 | 1994-04-20 | Smithkline Beecham Corp | Novel compounds |
| GB9405076D0 (en) | 1994-03-16 | 1994-04-27 | Inst Of Ophtalmology | A medical use of matrix metalloproteinase inhibitors |
| DE4411311A1 (de) | 1994-03-31 | 1995-10-05 | Basf Ag | Verfahren zur Herstellung von lagerstabilen wäßrigen Lösungen von Vinylamin-Einheiten enthaltenden Polymerisaten |
| GB9501737D0 (en) | 1994-04-25 | 1995-03-22 | Hoffmann La Roche | Hydroxamic acid derivatives |
| AU2394795A (en) | 1994-04-28 | 1995-11-29 | Du Pont Merck Pharmaceutical Company, The | Hydroxamic acid and amino acid derivatives and their use as anti-arthritic agents |
| JPH07304770A (ja) | 1994-05-11 | 1995-11-21 | Kanebo Ltd | 新規ベンゾアゼピノン誘導体 |
| DE69510198T2 (de) | 1994-05-28 | 1999-10-28 | British Biotech Pharmaceuticals Ltd., Cowley | Succinyl hydroxamsäure-, n-formyl-n-hydroxy-aminocarbonsäure- und succinsäureamid-derivate und ihre verwendung als metalloprotease-inhibitoren |
| GB9411088D0 (en) | 1994-06-03 | 1994-07-27 | Hoffmann La Roche | Hydroxylamine derivatives |
| GB9411598D0 (en) | 1994-06-09 | 1994-08-03 | Hoffmann La Roche | Hydroxamic acid derivatives |
| GB9412350D0 (en) | 1994-06-20 | 1994-08-10 | Fujisawa Pharmaceutical Co | New compound and its preparation |
| US5962529A (en) | 1994-06-22 | 1999-10-05 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
| GB9416897D0 (en) | 1994-08-20 | 1994-10-12 | British Biotech Pharm | Metalloproteinase inhibitors |
| NZ325559A (en) | 1995-12-08 | 2000-01-28 | Agouron Pharmaceuticals Inc Ag | Metalloproteinase inhibitors, pharmaceutical compoMetalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical usitions containing them and their pharmaceutical uses, and methods and intermediates useful for theises, and methods and intermediates useful for their preparation r preparation |
| DE69716449T2 (de) | 1996-08-28 | 2003-08-07 | The Procter & Gamble Company, Cincinnati | Substituierte zyklische amine als metalloproteaseinhibitoren |
-
1999
- 1999-03-23 US US09/274,564 patent/US6329418B1/en not_active Expired - Fee Related
- 1999-04-09 CA CA002328211A patent/CA2328211A1/en not_active Abandoned
- 1999-04-09 BR BR9909620-0A patent/BR9909620A/pt not_active IP Right Cessation
- 1999-04-09 PL PL99343529A patent/PL343529A1/xx unknown
- 1999-04-09 ID IDW20002350A patent/ID26925A/id unknown
- 1999-04-09 KR KR10-2000-7011405A patent/KR100400507B1/ko not_active IP Right Cessation
- 1999-04-09 NZ NZ507076A patent/NZ507076A/xx unknown
- 1999-04-09 WO PCT/US1999/007826 patent/WO1999052868A1/en not_active Application Discontinuation
- 1999-04-09 IL IL13873899A patent/IL138738A0/xx unknown
- 1999-04-09 HU HU0102195A patent/HUP0102195A3/hu unknown
- 1999-04-09 SK SK1546-2000A patent/SK15462000A3/sk unknown
- 1999-04-09 TR TR2000/02971T patent/TR200002971T2/xx unknown
- 1999-04-09 CN CN99805010A patent/CN1297436A/zh active Pending
- 1999-04-09 AU AU35522/99A patent/AU753048B2/en not_active Ceased
- 1999-04-09 EP EP99917387A patent/EP1073635A1/en not_active Withdrawn
- 1999-04-09 JP JP2000543431A patent/JP2002511448A/ja not_active Withdrawn
- 1999-04-14 PE PE1999000301A patent/PE20000425A1/es not_active Application Discontinuation
- 1999-04-14 CO CO99022198A patent/CO5011039A1/es unknown
- 1999-04-14 AR ARP990101724A patent/AR029145A1/es not_active Application Discontinuation
-
2000
- 2000-09-21 ZA ZA200005047A patent/ZA200005047B/en unknown
- 2000-10-16 NO NO20005196A patent/NO20005196L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0102195A3 (en) | 2001-12-28 |
| WO1999052868A1 (en) | 1999-10-21 |
| CO5011039A1 (es) | 2001-02-28 |
| CA2328211A1 (en) | 1999-10-21 |
| BR9909620A (pt) | 2000-12-19 |
| TR200002971T2 (tr) | 2001-02-21 |
| ZA200005047B (en) | 2001-06-06 |
| NZ507076A (en) | 2003-04-29 |
| AR029145A1 (es) | 2003-06-18 |
| AU3552299A (en) | 1999-11-01 |
| AU753048B2 (en) | 2002-10-03 |
| SK15462000A3 (sk) | 2001-06-11 |
| CN1297436A (zh) | 2001-05-30 |
| US6329418B1 (en) | 2001-12-11 |
| KR100400507B1 (ko) | 2003-10-08 |
| PE20000425A1 (es) | 2000-07-13 |
| HUP0102195A2 (hu) | 2001-11-28 |
| PL343529A1 (en) | 2001-08-27 |
| NO20005196D0 (no) | 2000-10-16 |
| ID26925A (id) | 2001-02-22 |
| JP2002511448A (ja) | 2002-04-16 |
| IL138738A0 (en) | 2001-10-31 |
| KR20010042694A (ko) | 2001-05-25 |
| EP1073635A1 (en) | 2001-02-07 |
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