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MXPA05001096A - Metodos para tratamiento o prevencion de enfermedades autoinmunes con compuestos de 2,4-diamino-pirimidina. - Google Patents

Metodos para tratamiento o prevencion de enfermedades autoinmunes con compuestos de 2,4-diamino-pirimidina.

Info

Publication number
MXPA05001096A
MXPA05001096A MXPA05001096A MXPA05001096A MXPA05001096A MX PA05001096 A MXPA05001096 A MX PA05001096A MX PA05001096 A MXPA05001096 A MX PA05001096A MX PA05001096 A MXPA05001096 A MX PA05001096A MX PA05001096 A MXPA05001096 A MX PA05001096A
Authority
MX
Mexico
Prior art keywords
treating
autoimmune diseases
methods
pyrimidinediamine compounds
preventing autoimmune
Prior art date
Application number
MXPA05001096A
Other languages
English (en)
Inventor
Somasekhar Bhamidipati
Original Assignee
Rigel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31721742&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA05001096(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Publication of MXPA05001096A publication Critical patent/MXPA05001096A/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
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Abstract

El presente invento provee compuestos para tratar o prevenir enfermedades autoinmunes con compuestos de 2,4-diamino-pirimidina, asi como metodos para tratar, prevenir o aliviar sintomas asociados con dichas enfermedades. Ejemplos especificos de enfermedades autoinmunes que pueden ser tratadas o prevenidas con los compuestos incluyen artritis reumatoide, y/o sus sintomas asociados, lupus eritematoso sistemico y/o sus sintomas asociados y esclerosis multiple y/o sus sintomas asociados.
MXPA05001096A 2002-07-29 2003-07-29 Metodos para tratamiento o prevencion de enfermedades autoinmunes con compuestos de 2,4-diamino-pirimidina. MXPA05001096A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39967302P 2002-07-29 2002-07-29
US44394903P 2003-01-31 2003-01-31
US45233903P 2003-03-06 2003-03-06
US10/631,029 US7517886B2 (en) 2002-07-29 2003-07-29 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
PCT/US2003/024087 WO2004014382A1 (en) 2002-07-29 2003-07-29 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds

Publications (1)

Publication Number Publication Date
MXPA05001096A true MXPA05001096A (es) 2005-11-23

Family

ID=31721742

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05001096A MXPA05001096A (es) 2002-07-29 2003-07-29 Metodos para tratamiento o prevencion de enfermedades autoinmunes con compuestos de 2,4-diamino-pirimidina.

Country Status (25)

Country Link
US (5) US7517886B2 (es)
EP (1) EP1534286B1 (es)
JP (2) JP2006514989A (es)
CN (2) CN103169708B (es)
AT (1) ATE451104T1 (es)
AU (1) AU2003265336B8 (es)
BR (1) BR0313059B8 (es)
CA (1) CA2492325C (es)
CY (1) CY1110292T1 (es)
DE (1) DE60330466D1 (es)
DK (1) DK1534286T3 (es)
ES (2) ES2337782T3 (es)
HK (2) HK1079978A1 (es)
HR (1) HRP20050089B1 (es)
IL (3) IL166241A (es)
IS (1) IS2923B (es)
MX (1) MXPA05001096A (es)
NO (1) NO332550B1 (es)
NZ (1) NZ537752A (es)
PL (1) PL216744B1 (es)
RS (1) RS51752B (es)
RU (1) RU2659777C9 (es)
SE (1) SE0500203L (es)
SG (1) SG176311A1 (es)
WO (1) WO2004014382A1 (es)

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TWI329105B (en) * 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
MXPA05001096A (es) 2002-07-29 2005-11-23 Rigel Pharmaceuticals Inc Metodos para tratamiento o prevencion de enfermedades autoinmunes con compuestos de 2,4-diamino-pirimidina.
PL377795A1 (pl) * 2002-11-28 2006-02-20 Schering Aktiengesellschaft Pirymidyny będące inhibitorami Chk, Pdk i Akt, sposób ich wytwarzania oraz ich zastosowanie jako środków farmaceutycznych
UA80767C2 (en) * 2002-12-20 2007-10-25 Pfizer Prod Inc Pyrimidine derivatives for the treatment of abnormal cell growth
CL2004000306A1 (es) * 2003-02-20 2005-04-08 Tibotec Pharm Ltd Compuestos derivados de pirimidina sustituidas con indano; proceso para su preparacion; composicion farmaceutica que lo comprende; combinacion farmaceutica; y su uso para el tratamiento o profilaxis de una enfermedad infecciosa.
KR20120062863A (ko) 2003-07-30 2012-06-14 리겔 파마슈티칼스, 인크. 자가면역 질환의 치료 또는 예방에 사용하기 위한 2,4-피리미딘디아민 화합물
WO2005012262A1 (en) * 2003-07-30 2005-02-10 Cyclacel Limited 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors
ES2365223T3 (es) * 2003-08-07 2011-09-26 Rigel Pharmaceuticals, Inc. Compuestos 2,4-pirimidindiamínicos y usos como agentes antiproliferativos.
MXPA06001759A (es) * 2003-08-15 2006-05-12 Novartis Ag 2,4-pirimidinadiaminas utiles en el tratamiento de enfermedades neoplasticas, desordenes del sistema inmune e inflamatorios.
WO2005096784A2 (en) 2004-04-08 2005-10-20 Targegen, Inc. Benzotriazine inhibitors of kinases
WO2005118544A2 (en) 2004-05-18 2005-12-15 Rigel Pharmaceuticals, Inc. Cycloalkyl substituted pyrimidinediamine compounds and their uses
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