Nothing Special   »   [go: up one dir, main page]

MX2023004315A - Anticuerpo neutralizante que se une a il-17a humana y a il-17f humana para usarse en el tratamiento de artritis. - Google Patents

Anticuerpo neutralizante que se une a il-17a humana y a il-17f humana para usarse en el tratamiento de artritis.

Info

Publication number
MX2023004315A
MX2023004315A MX2023004315A MX2023004315A MX2023004315A MX 2023004315 A MX2023004315 A MX 2023004315A MX 2023004315 A MX2023004315 A MX 2023004315A MX 2023004315 A MX2023004315 A MX 2023004315A MX 2023004315 A MX2023004315 A MX 2023004315A
Authority
MX
Mexico
Prior art keywords
treatment
antibodies
methods
dermatological
psoriasis
Prior art date
Application number
MX2023004315A
Other languages
English (en)
Inventor
Stevan Graham Shaw
Sophie Glatt
Lucian Ionescu
Margaret Jones
Ruth Oliver
Foteini Strimenopoulou
Vajjah Venkata Pavan Kumar
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57223670&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2023004315(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Publication of MX2023004315A publication Critical patent/MX2023004315A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La invención se refiere a usos terapéuticos de moléculas de anticuerpo que tienen especificidad por determinantes antigénicos de IL-17A e IL-17F en el tratamiento de enfermedades dermatológicas y reumatológicas, tales como psoriasis, artritis psoriásica y espondiloartritis axial.
MX2023004315A 2015-10-27 2018-04-24 Anticuerpo neutralizante que se une a il-17a humana y a il-17f humana para usarse en el tratamiento de artritis. MX2023004315A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562246989P 2015-10-27 2015-10-27
US201662303230P 2016-03-03 2016-03-03
US201662346826P 2016-06-07 2016-06-07
US201662405546P 2016-10-07 2016-10-07

Publications (1)

Publication Number Publication Date
MX2023004315A true MX2023004315A (es) 2023-05-08

Family

ID=57223670

Family Applications (4)

Application Number Title Priority Date Filing Date
MX2018005031A MX2018005031A (es) 2015-10-27 2016-10-26 Metodos de tratamiento con anticuerpos anti interleucina 17a/17f (il-17a/f).
MX2022009380A MX2022009380A (es) 2015-10-27 2018-04-24 Metodos de tratamiento con anticuerpos anti interleucina 17a/17f (il-17a/f).
MX2022009379A MX2022009379A (es) 2015-10-27 2018-04-24 Metodos de tratamiento con anticuerpos anti interleucina 17a/17f (il-17a/f).
MX2023004315A MX2023004315A (es) 2015-10-27 2018-04-24 Anticuerpo neutralizante que se une a il-17a humana y a il-17f humana para usarse en el tratamiento de artritis.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
MX2018005031A MX2018005031A (es) 2015-10-27 2016-10-26 Metodos de tratamiento con anticuerpos anti interleucina 17a/17f (il-17a/f).
MX2022009380A MX2022009380A (es) 2015-10-27 2018-04-24 Metodos de tratamiento con anticuerpos anti interleucina 17a/17f (il-17a/f).
MX2022009379A MX2022009379A (es) 2015-10-27 2018-04-24 Metodos de tratamiento con anticuerpos anti interleucina 17a/17f (il-17a/f).

Country Status (15)

Country Link
US (3) US11492396B2 (es)
EP (1) EP3368570A1 (es)
JP (4) JP6931648B2 (es)
KR (1) KR20180067676A (es)
CN (2) CN108350068A (es)
AU (2) AU2016347471B2 (es)
BR (1) BR112018008075A2 (es)
CA (1) CA3001260A1 (es)
CL (3) CL2018001135A1 (es)
CO (1) CO2018004493A2 (es)
IL (1) IL258515A (es)
MX (4) MX2018005031A (es)
RU (1) RU2754683C2 (es)
SG (2) SG10202112586WA (es)
WO (1) WO2017072183A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200277369A1 (en) * 2017-11-20 2020-09-03 Novartis Ag Method of treating hidradentitis suppurativa with il-17 antagonists
GB201719447D0 (en) * 2017-11-23 2018-01-10 Ucb Biopharma Sprl Pharmaceutical composition
WO2021050563A1 (en) * 2019-09-09 2021-03-18 The Rockefeller University Antibody treatment for lesional tissue of hidradenitis suppurativa
WO2022127842A1 (zh) * 2020-12-17 2022-06-23 上海华奥泰生物药业股份有限公司 靶向il-17a和il-36r的双特异性抗体及其应用

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
DK336987D0 (da) 1987-07-01 1987-07-01 Novo Industri As Immobiliseringsmetode
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
GB8719042D0 (en) 1987-08-12 1987-09-16 Parker D Conjugate compounds
GB8720833D0 (en) 1987-09-04 1987-10-14 Celltech Ltd Recombinant dna product
EP1997891A1 (en) 1988-09-02 2008-12-03 Dyax Corporation Generation and selection of recombinant varied binding proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8907617D0 (en) 1989-04-05 1989-05-17 Celltech Ltd Drug delivery system
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US5780225A (en) 1990-01-12 1998-07-14 Stratagene Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
WO1991010737A1 (en) 1990-01-11 1991-07-25 Molecular Affinities Corporation Production of antibodies using gene libraries
ATE356869T1 (de) 1990-01-12 2007-04-15 Amgen Fremont Inc Bildung von xenogenen antikörpern
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
CA2090126C (en) 1990-08-02 2002-10-22 John W. Schrader Methods for the production of proteins with a desired function
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5770429A (en) 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
DK0814159T3 (da) 1990-08-29 2005-10-24 Genpharm Int Transgene, ikke-humane dyr, der er i stand til at danne heterologe antistoffer
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5698426A (en) 1990-09-28 1997-12-16 Ixsys, Incorporated Surface expression libraries of heteromeric receptors
DE69129154T2 (de) 1990-12-03 1998-08-20 Genentech, Inc., South San Francisco, Calif. Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
ATE269401T1 (de) 1991-04-10 2004-07-15 Scripps Research Inst Bibliotheken heterodimerer rezeptoren mittels phagemiden
GB9112536D0 (en) 1991-06-11 1991-07-31 Celltech Ltd Chemical compounds
GB9113120D0 (en) 1991-06-18 1991-08-07 Kodak Ltd Photographic processing apparatus
GB9120467D0 (en) 1991-09-26 1991-11-06 Celltech Ltd Anti-hmfg antibodies and process for their production
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
US5885793A (en) 1991-12-02 1999-03-23 Medical Research Council Production of anti-self antibodies from antibody segment repertoires and displayed on phage
US5733743A (en) 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
WO1995015982A2 (en) 1993-12-08 1995-06-15 Genzyme Corporation Process for generating specific antibodies
DK0744958T3 (da) 1994-01-31 2003-10-20 Univ Boston Polyklonale antistofbiblioteker
FR2716640B1 (fr) 1994-02-28 1996-05-03 Procedes Machines Speciales Dispositif de centrage et de blocage d'une pièce en vue de son rodage à l'aide d'un rodoir à expansion.
US5516637A (en) 1994-06-10 1996-05-14 Dade International Inc. Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
JP2978435B2 (ja) 1996-01-24 1999-11-15 チッソ株式会社 アクリロキシプロピルシランの製造方法
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
US20070160576A1 (en) 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
US6908963B2 (en) 2001-10-09 2005-06-21 Nektar Therapeutics Al, Corporation Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith
US7993864B2 (en) 2002-12-03 2011-08-09 Ucb Pharma S.A. Assay for identifying antibody producing cells
GB0303337D0 (en) 2003-02-13 2003-03-19 Celltech R&D Ltd Biological products
GB0312481D0 (en) 2003-05-30 2003-07-09 Celltech R&D Ltd Antibodies
GB0315457D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
GB0315450D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
CA2527020A1 (en) 2003-07-01 2005-01-13 Celltech R & D Limited Modified antibody fab fragments
GB0411186D0 (en) 2004-05-19 2004-06-23 Celltech R&D Ltd Biological products
GB0412181D0 (en) 2004-06-01 2004-06-30 Celltech R&D Ltd Biological products
AU2007300393B2 (en) 2006-02-10 2012-05-31 Zymogenetics, Inc. Soluble IL-17RCx4 and methods of using in inflammation
CA2646478A1 (en) * 2006-03-10 2007-09-20 Zymogenetics, Inc. Antibodies that bind both il-17a and il-17f and methods of using the same
TW200815469A (en) 2006-06-23 2008-04-01 Astrazeneca Ab Compounds
GB0620729D0 (en) * 2006-10-18 2006-11-29 Ucb Sa Biological products
CL2008000883A1 (es) * 2007-03-28 2008-10-03 Wyeth6 3 Metodo de deteccion de compuestos capaces de antagonizar la senalizacion de il-17f/il-17a; compuesto identificado por dicho metodo; uso de una cantidad de un antagonista de senalizacion de il-17f/il-17a, composicion farmaceutica que comprende dicho a
CN104004088B (zh) 2007-09-26 2017-11-07 Ucb医药有限公司 双特异性抗体融合物
GB0807413D0 (en) * 2008-04-23 2008-05-28 Ucb Pharma Sa Biological products
KR101508086B1 (ko) * 2008-05-05 2015-04-07 노비뮨 에스 에이 항-il-17a/il-17f 교차-반응성 항체 및 그의 사용 방법
US8790642B2 (en) * 2008-08-29 2014-07-29 Genentech, Inc. Cross-reactive and bispecific anti-IL-17A/F antibodies
CN102164965B (zh) 2008-09-26 2016-03-30 Ucb医药有限公司 生物产品
RU2394575C1 (ru) * 2009-04-13 2010-07-20 Федеральное государственное учреждение "Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии Федерального агентства по высокотехнологичной медицинской помощи" (ФГУ "УрНИИДВиИ Росмедтехнологий") Способ лечения псориаза
BRPI1014544B8 (pt) 2009-05-05 2021-05-25 Novimmune Sa anticorpo anti-il-17f monoclonal totalmente humano isolado e composição farmacêutica compreendendo o mesmo
WO2011030107A1 (en) 2009-09-10 2011-03-17 Ucb Pharma S.A. Multivalent antibodies
GB0920127D0 (en) 2009-11-17 2009-12-30 Ucb Pharma Sa Antibodies
GB201000467D0 (en) 2010-01-12 2010-02-24 Ucb Pharma Sa Antibodies
LT2625199T (lt) * 2010-10-08 2018-03-12 Novartis Ag Psoriazės gydymo būdai panaudojant il-17 antagonistus
SG191906A1 (en) * 2011-01-14 2013-08-30 Ucb Pharma Sa Antibody molecules which bind il-17a and il-17f
UA117218C2 (uk) * 2011-05-05 2018-07-10 Мерк Патент Гмбх Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
US20150064193A1 (en) 2011-11-21 2015-03-05 Novartis Ag Methods of treating psoriatic arthritis (psa) using il-17 antagonists and psa response or non-response alleles
MX2014012640A (es) 2012-04-20 2015-01-15 Novartis Ag Metodos para el tratamiento de espondilitis anquilosante usando antagonistas de il-17.
GB201213571D0 (en) 2012-07-31 2012-09-12 Univ Leuven Kath Growth factor cocktail to enhnce osteogenic differentiayion of mesenchymal
EP3656786B1 (en) 2013-02-08 2024-08-28 Novartis AG Anti-il-17a antibodies and their use in treating autoimmune and inflammatory disorders
WO2014155278A2 (en) 2013-03-26 2014-10-02 Novartis Ag Methods of treating autoimmune diseases using il-17 antagonists
ES2981697T3 (es) 2014-09-10 2024-10-10 Novartis Ag Uso de antagonistas de IL-17 para inhibir la progresión del daño estructural en pacientes con artritis psoriásica
CN108367074A (zh) 2015-10-19 2018-08-03 诺华股份有限公司 使用白介素-17(il-17)拮抗剂治疗放射学阴性中轴型脊柱关节炎的方法
GB201522391D0 (en) 2015-12-18 2016-02-03 Ucb Biopharma Sprl Antibody molecules
RU2680011C2 (ru) 2016-04-29 2019-02-14 Закрытое Акционерное Общество "Биокад" Триспецифические антитела против il-17a, il-17f и другой провоспалительной молекулы

Also Published As

Publication number Publication date
MX2022009379A (es) 2022-09-07
JP2021130707A (ja) 2021-09-09
JP2021119168A (ja) 2021-08-12
CL2021002815A1 (es) 2022-07-29
JP2023025019A (ja) 2023-02-21
AU2016347471A1 (en) 2018-05-10
SG11201802887PA (en) 2018-05-30
EP3368570A1 (en) 2018-09-05
US20230287100A1 (en) 2023-09-14
CO2018004493A2 (es) 2018-11-30
RU2754683C2 (ru) 2021-09-06
CN108350068A (zh) 2018-07-31
SG10202112586WA (en) 2021-12-30
IL258515A (en) 2018-05-31
CA3001260A1 (en) 2017-05-04
JP6931750B2 (ja) 2021-09-08
JP2018535961A (ja) 2018-12-06
RU2018118029A (ru) 2019-12-04
MX2022009380A (es) 2022-09-07
WO2017072183A1 (en) 2017-05-04
RU2018118029A3 (es) 2020-09-17
US20230279093A1 (en) 2023-09-07
CL2018001135A1 (es) 2019-05-10
CN116059350A (zh) 2023-05-05
CL2021002816A1 (es) 2022-07-29
JP6931648B2 (ja) 2021-09-08
US11492396B2 (en) 2022-11-08
US20190292255A1 (en) 2019-09-26
BR112018008075A2 (pt) 2018-12-04
AU2016347471B2 (en) 2023-08-03
KR20180067676A (ko) 2018-06-20
JP7176044B2 (ja) 2022-11-21
AU2023255037A1 (en) 2023-11-16
MX2018005031A (es) 2018-06-13

Similar Documents

Publication Publication Date Title
MX2022006575A (es) Uso de anticuerpos anti-il-23a para tratar enfermedades inflamatorias.
MX2022009379A (es) Metodos de tratamiento con anticuerpos anti interleucina 17a/17f (il-17a/f).
EA201300819A1 (ru) Молекулы антител, которые связываются с il-17a и il-17f
PE20170704A1 (es) Agente terapeutico que induce citotoxicidad
MY175878A (en) Anti-il-17 antibodies, a method for producing and using thereof
CO2018006667A2 (es) Moléculas de anticuerpo multiespecífico que tienen especificidad para tnf-alfa, il-17a e il-17f
EA201290360A1 (ru) Гуманизированные антитела против il-22ra человека
PH12021550521A1 (en) Antibodies that potently neutralize rabies virus and other lyssaviruses and uses thereof
MY184189A (en) Methods of treating nail and scalp psoriasis
UA117466C2 (uk) СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
CY1125041T1 (el) Αντισωματα anti-il-22r
EA201891594A1 (ru) Антитела к il-17c
MX2017004196A (es) Anticuerpos contra ticagrelor y metodos de uso.
CL2023002975A1 (es) Anticuerpo multiespecífico con especificidad de unión para il-13 e il-17 humanas
MX2018012410A (es) Metodos para tratar enfermedades inflamatorias.
MX2022007117A (es) Anticuerpo con especificidad de enlace para la il-13 humana.
EA201890983A1 (ru) Способы лечения с использованием анти-il-17a/f антител
MX2018007221A (es) Moleculas de anticuerpos que se unen al factor de necrosis tumoral alfa (tnf alfa).
AR106507A1 (es) Métodos para el tratamiento de enfermedades dermatológicas y reumatoideas
TH1601005297A (th) แอนติ-il 17 แอนติบอดี, วิธีการสำหรับการผลิตและการใช้ของสิ่งนั้น