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MX2020005305A - Peliculas tipo saco que se disuelven oralmente con alta concentracion de ingrediente activo. - Google Patents

Peliculas tipo saco que se disuelven oralmente con alta concentracion de ingrediente activo.

Info

Publication number
MX2020005305A
MX2020005305A MX2020005305A MX2020005305A MX2020005305A MX 2020005305 A MX2020005305 A MX 2020005305A MX 2020005305 A MX2020005305 A MX 2020005305A MX 2020005305 A MX2020005305 A MX 2020005305A MX 2020005305 A MX2020005305 A MX 2020005305A
Authority
MX
Mexico
Prior art keywords
active ingredient
pouch
dosage form
film layer
film
Prior art date
Application number
MX2020005305A
Other languages
English (en)
Inventor
Christoph Schmitz
Marius Bauer
Original Assignee
Lts Lohmann Therapie Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmann Therapie Systeme Ag filed Critical Lts Lohmann Therapie Systeme Ag
Publication of MX2020005305A publication Critical patent/MX2020005305A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invención se refiere a una forma de dosificación para un ingrediente activo, que se va a disolver en la cavidad oral, que comprende una primera capa de película y una segunda capa de película que está dispuesta sobre la primera capa de película, en donde la composición de la primera capa de película puede ser idéntica a esa de la segunda y comprende un polímero soluble en agua, dicha primera y la segunda capas de película están interconectadas mediante sus bordes de superposición a modo de formar por lo menos una cavidad y esta cavidad es llenada con un ingrediente activo; en esta configuración, la forma de dosificación toma la forma de un saco formado de dos capas de película soluble en agua de modo que dichas capas de película se disuelven cuando el saco se pone en la boca, y un ingrediente activo contenido en dicho saco puede ser liberado; esta configuración desaco hace posible tener un mayor contenido del ingrediente activo que las películas de OTF comparables mientras evita el esfuerzo térmico en dicho ingrediente activo durante la producción de la forma de dosificación; se retienen sustancialmente las propiedades ventajosas de las formas de dosificación de película delgada conocidas; la invención también se refiere a un método para la producción de la forma de dosificación.
MX2020005305A 2017-11-21 2018-11-21 Peliculas tipo saco que se disuelven oralmente con alta concentracion de ingrediente activo. MX2020005305A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102017127434.0A DE102017127434A1 (de) 2017-11-21 2017-11-21 Taschenförmige oral auflösende Filme mit hoher Wirkstoffbeladung
PCT/EP2018/082094 WO2019101800A2 (de) 2017-11-21 2018-11-21 Taschenförmige oral auflösende filme mit hoher wirkstoffbeladung

Publications (1)

Publication Number Publication Date
MX2020005305A true MX2020005305A (es) 2020-08-17

Family

ID=64604603

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020005305A MX2020005305A (es) 2017-11-21 2018-11-21 Peliculas tipo saco que se disuelven oralmente con alta concentracion de ingrediente activo.

Country Status (12)

Country Link
US (1) US20200289402A1 (es)
EP (1) EP3713543A2 (es)
JP (2) JP7171722B2 (es)
KR (2) KR20200090201A (es)
CN (1) CN111372569A (es)
AU (1) AU2018371143B2 (es)
BR (1) BR112020008892A2 (es)
CA (1) CA3082201C (es)
DE (1) DE102017127434A1 (es)
MX (1) MX2020005305A (es)
RU (1) RU2742415C1 (es)
WO (1) WO2019101800A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12161755B2 (en) 2020-11-14 2024-12-10 Regents Of The University Of Minnesota Sustained release device for treatment of Parkinson's disease and other disorders
JP2021041261A (ja) * 2020-12-17 2021-03-18 株式会社三洋物産 遊技機
DE102021100783A1 (de) 2021-01-15 2022-07-21 Lts Lohmann Therapie-Systeme Ag. Mehrschichtiger oraler dünnfilm
DE102021100782B3 (de) * 2021-01-15 2022-07-14 Lts Lohmann Therapie-Systeme Ag. Otf-verbindung durch nähen
KR102693920B1 (ko) * 2021-10-27 2024-08-08 권태진 약품의 맛과 향을 물리적으로 마스킹하는 천연성분 기반의 점착 필름형 투약보조 영양제

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
US5079018A (en) 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5393528A (en) 1992-05-07 1995-02-28 Staab; Robert J. Dissolvable device for contraception or delivery of medication
US20050048102A1 (en) * 1997-10-16 2005-03-03 Virotex Corporation Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces
DE19837073A1 (de) * 1998-08-17 2000-03-23 Lohmann Therapie Syst Lts Folienförmige Wirkstoffträger
US6596298B2 (en) 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
DE10032456A1 (de) * 2000-07-04 2002-01-31 Lohmann Therapie Syst Lts Schnell zerfallende Darreichungsform zur Freisetzung von Wirkstoffen im Mundraum oder in Körperhöhlen
US8268333B2 (en) * 2001-04-24 2012-09-18 Lintec Corporation Orally administered agent and an orally administered agent/supporting substrate complex
DE102004017030A1 (de) * 2004-04-02 2005-10-20 Schering Ag Flachkapseln
US20050196355A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Film products having controlled disintegration properties
US7946296B2 (en) * 2006-05-26 2011-05-24 Philip Morris Usa Inc. Dissolvable tobacco film strips and method of making the same
DE102006027791A1 (de) * 2006-06-16 2007-12-20 Lts Lohmann Therapie-Systeme Ag AchE-NMDA-Kombinationswafer
US20080166395A1 (en) * 2007-01-04 2008-07-10 Roush Steven H Article for delivering substrates to the oral cavity
KR20100131530A (ko) * 2008-04-07 2010-12-16 가부시키가이샤 쓰키오카 경구투여제제
US20110014268A1 (en) * 2008-04-07 2011-01-20 Tsukioka Co., Ltd Formulation for oral administration
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Also Published As

Publication number Publication date
US20200289402A1 (en) 2020-09-17
DE102017127434A1 (de) 2019-05-23
BR112020008892A2 (pt) 2020-10-20
CN111372569A (zh) 2020-07-03
EP3713543A2 (de) 2020-09-30
KR20230131956A (ko) 2023-09-14
CA3082201A1 (en) 2019-05-31
AU2018371143A1 (en) 2020-06-11
RU2742415C1 (ru) 2021-02-05
JP2022141870A (ja) 2022-09-29
KR20200090201A (ko) 2020-07-28
JP2021504318A (ja) 2021-02-15
CA3082201C (en) 2023-08-22
AU2018371143B2 (en) 2021-09-16
JP7171722B2 (ja) 2022-11-15
WO2019101800A2 (de) 2019-05-31
WO2019101800A3 (de) 2019-07-11

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