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MX2016003855A - Composicion de vacuna de circovirus porcino tipo 2b divergente y procedimientos de uso. - Google Patents

Composicion de vacuna de circovirus porcino tipo 2b divergente y procedimientos de uso.

Info

Publication number
MX2016003855A
MX2016003855A MX2016003855A MX2016003855A MX2016003855A MX 2016003855 A MX2016003855 A MX 2016003855A MX 2016003855 A MX2016003855 A MX 2016003855A MX 2016003855 A MX2016003855 A MX 2016003855A MX 2016003855 A MX2016003855 A MX 2016003855A
Authority
MX
Mexico
Prior art keywords
vaccine composition
methods
pcv2b
pcv2b divergent
divergent vaccine
Prior art date
Application number
MX2016003855A
Other languages
English (en)
Inventor
Gregory Paul Nitzel
David Ewell Slade
Original Assignee
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of MX2016003855A publication Critical patent/MX2016003855A/es

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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C12N7/045—Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/552—Veterinary vaccine
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    • A61K2039/55511—Organic adjuvants
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N2710/14011—Baculoviridae
    • C12N2710/14041—Use of virus, viral particle or viral elements as a vector
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    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2750/10044—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
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    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10071—Demonstrated in vivo effect

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
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  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
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  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención proporciona una composición de vacuna para proteger a los cerdos frente al PCV2, incluyendo una cepa de circovirus porcino tipo 2b (PCV2b) divergente altamente virulenta, incluyendo la composición un polipéptido de ORF2 de PCV2b divergente, en donde el polipéptido de ORF2 comprende leucina (L) en la posición 89, treonina (T) en la posición 90 y asparagina (N) en la posición 134, de acuerdo con la numeración de SEQ ID NO: 1 en el presente documento.
MX2016003855A 2013-09-25 2014-09-24 Composicion de vacuna de circovirus porcino tipo 2b divergente y procedimientos de uso. MX2016003855A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361882289P 2013-09-25 2013-09-25
PCT/US2014/057190 WO2015048115A1 (en) 2013-09-25 2014-09-24 Pcv2b divergent vaccine composition and methods of use

Publications (1)

Publication Number Publication Date
MX2016003855A true MX2016003855A (es) 2016-08-04

Family

ID=51688446

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MX2016003855A MX2016003855A (es) 2013-09-25 2014-09-24 Composicion de vacuna de circovirus porcino tipo 2b divergente y procedimientos de uso.

Country Status (12)

Country Link
US (1) US9987348B2 (es)
EP (2) EP3049106A1 (es)
JP (2) JP6821429B2 (es)
KR (2) KR20160046879A (es)
CN (1) CN105579060B (es)
BR (1) BR112016006192A2 (es)
CA (1) CA2925281C (es)
HK (1) HK1225645A1 (es)
MX (1) MX2016003855A (es)
PH (1) PH12016500473B1 (es)
RU (1) RU2662685C2 (es)
WO (1) WO2015048115A1 (es)

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EP2994162B1 (en) 2013-05-08 2021-04-07 Pharmgate Biologics Inc. Vaccine for pcv2 and mycoplasma
MX2016003855A (es) * 2013-09-25 2016-08-04 Zoetis Services Llc Composicion de vacuna de circovirus porcino tipo 2b divergente y procedimientos de uso.
CA3016374A1 (en) * 2016-03-07 2017-11-02 Virginia Tech Intellectual Properties, Inc Chimeric porcine circovirus type 2 (pcv2) vaccines
GB201614799D0 (en) * 2016-09-01 2016-10-19 Glaxosmithkline Biologicals Sa Compositions
CN106754980A (zh) * 2016-12-29 2017-05-31 福州大学 Pcv2型衣壳蛋白基因、表达菌株及可溶性表达方法
MX2020003626A (es) * 2017-10-17 2021-08-12 Intervet Int Bv Expresión recombinante de la proteína orf2 de pcv2b en células de insecto.
MX2020013484A (es) * 2018-06-11 2021-05-27 Ceva Sante Animale Vacunacion contra circovirus porcinos.
CN110606873B (zh) * 2019-09-09 2021-05-04 武汉科前生物股份有限公司 猪圆环病毒2d型与3型Cap蛋白二联亚单位疫苗及其制备方法与应用
KR20230073462A (ko) * 2021-11-19 2023-05-26 주식회사 이노백 신규한 재조합 돼지 써코바이러스 2형 단백질 및 이의 용도
CN115960259B (zh) * 2022-10-07 2023-11-24 浙江大学 一种模块化组装双组分纳米颗粒制备方法及其应用
WO2024096648A1 (ko) * 2022-11-03 2024-05-10 주식회사 옵티팜 신규한 재조합 pcv2d 항원 및 이의 용도
CN117100851A (zh) * 2023-10-23 2023-11-24 成都依思康生物科技有限公司 一种佐剂、疫苗组合物及其制备方法和应用

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CA2925281A1 (en) 2015-04-02
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RU2016110430A (ru) 2017-10-30
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KR102319843B1 (ko) 2021-10-29
US9987348B2 (en) 2018-06-05
PH12016500473A1 (en) 2016-05-16
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EP3049106A1 (en) 2016-08-03
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