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MX2010004625A - Nuevos derivados de 4(tetrazol-5-il)-quinazolina como agentes anticancerosos. - Google Patents

Nuevos derivados de 4(tetrazol-5-il)-quinazolina como agentes anticancerosos.

Info

Publication number
MX2010004625A
MX2010004625A MX2010004625A MX2010004625A MX2010004625A MX 2010004625 A MX2010004625 A MX 2010004625A MX 2010004625 A MX2010004625 A MX 2010004625A MX 2010004625 A MX2010004625 A MX 2010004625A MX 2010004625 A MX2010004625 A MX 2010004625A
Authority
MX
Mexico
Prior art keywords
tetrazol
quinazoline derivatives
novel
cancer agents
anti cancer
Prior art date
Application number
MX2010004625A
Other languages
English (en)
Inventor
Bhujanga Rao Adibhatla Kali Satya
Nannapaneni Venkaiah Chowdary
Durga Prasad Konakanchi
Subba Rao Pula
Lakshmi Ananthaneni
Muddasani Pulla Reddy
Original Assignee
Natco Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natco Pharma Ltd filed Critical Natco Pharma Ltd
Publication of MX2010004625A publication Critical patent/MX2010004625A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La invención se refiere a los derivados de 4-(tetrazol-5-il)-quina zolina sustituidos de la fórmula-I, o las sales farmacéuticamente aceptables de los mismos, que poseen actividad antiproliferativa tales como actividad anticancerosa y son en consecuencia útiles en los métodos de tratamiento del cuerpo humano o animal. La invención también se refiere a los procesos para la fabricación de derivados de 4-(tetrazol-5-il)-quinazolina sustituidos, a las composiciones farmacéuticas que contienen el compuesto y a su uso en la fabricación de medicamentos para la producción de un efecto antiproliferativo en un animal de sangre caliente tal como un ser humano.
MX2010004625A 2007-10-29 2008-10-28 Nuevos derivados de 4(tetrazol-5-il)-quinazolina como agentes anticancerosos. MX2010004625A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2445CH2007 2007-10-29
PCT/IN2008/000708 WO2009057139A2 (en) 2007-10-29 2008-10-28 Novel 4-(tetrazol-5-yl)-quinazoline derivatives as anti cancer agents

Publications (1)

Publication Number Publication Date
MX2010004625A true MX2010004625A (es) 2010-05-20

Family

ID=40433677

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010004625A MX2010004625A (es) 2007-10-29 2008-10-28 Nuevos derivados de 4(tetrazol-5-il)-quinazolina como agentes anticancerosos.

Country Status (15)

Country Link
US (1) US8080558B2 (es)
EP (1) EP2220054A2 (es)
JP (1) JP2011502141A (es)
KR (1) KR20100087185A (es)
CN (1) CN101878203A (es)
AU (1) AU2008320342B2 (es)
CA (1) CA2703767A1 (es)
EA (1) EA018716B1 (es)
GE (1) GEP20125603B (es)
MX (1) MX2010004625A (es)
MY (1) MY150054A (es)
NZ (1) NZ585357A (es)
UA (1) UA101168C2 (es)
WO (1) WO2009057139A2 (es)
ZA (1) ZA201002807B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130729B (zh) * 2011-12-05 2015-07-15 齐鲁制药有限公司 一种4-氯代-7-甲氧基喹唑啉-6-醇乙酸酯的制备方法
CN104981247A (zh) * 2012-09-06 2015-10-14 普莱希科公司 用于激酶调节的化合物和方法及其适应症
CN102993114B (zh) * 2012-10-11 2015-08-12 南通市华峰化工有限责任公司 一种1h-四唑-5-乙酸的生产方法
CN103204817B (zh) * 2013-04-16 2018-03-27 江西师范大学 4‑氰基喹唑啉衍生物的制备方法
DE102013008118A1 (de) * 2013-05-11 2014-11-13 Merck Patent Gmbh Arylchinazoline
RU2720810C2 (ru) * 2015-03-20 2020-05-13 Чиа Тай Тяньцин Фармасьютикал Груп Ко., Лтд. Соли производного хиназолина и способ их получения
WO2021083347A1 (zh) * 2019-11-01 2021-05-06 正大天晴药业集团股份有限公司 喹唑啉衍生物或其盐、或其药物组合物的用途
CN114437041B (zh) * 2022-02-25 2023-11-10 湖北科技学院 一类具有抗肿瘤活性的4-四唑基取代-3，4-二氢喹唑啉衍生物及其制备方法和应用

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Also Published As

Publication number Publication date
ZA201002807B (en) 2011-07-27
EP2220054A2 (en) 2010-08-25
NZ585357A (en) 2012-02-24
AU2008320342A2 (en) 2010-09-02
JP2011502141A (ja) 2011-01-20
AU2008320342B2 (en) 2012-07-26
US20100261740A1 (en) 2010-10-14
WO2009057139A2 (en) 2009-05-07
MY150054A (en) 2013-11-29
CN101878203A (zh) 2010-11-03
WO2009057139A3 (en) 2009-09-24
KR20100087185A (ko) 2010-08-03
AU2008320342A1 (en) 2009-05-07
CA2703767A1 (en) 2009-05-07
EA018716B1 (ru) 2013-10-30
EA201070543A1 (ru) 2010-12-30
GEP20125603B (en) 2012-08-10
US8080558B2 (en) 2011-12-20
UA101168C2 (ru) 2013-03-11

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