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MD4383C1 - Compusul acetato-(8-formilchinolintiosemicarbazono)cupru(II) care manifestă activitate antibacteriană - Google Patents

Compusul acetato-(8-formilchinolintiosemicarbazono)cupru(II) care manifestă activitate antibacteriană

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Publication number
MD4383C1
MD4383C1 MDA20150025A MD20150025A MD4383C1 MD 4383 C1 MD4383 C1 MD 4383C1 MD A20150025 A MDA20150025 A MD A20150025A MD 20150025 A MD20150025 A MD 20150025A MD 4383 C1 MD4383 C1 MD 4383C1
Authority
MD
Moldova
Prior art keywords
copper
compound
formylquinolinethiosemicarbazono
acetato
antibacterial activity
Prior art date
Application number
MDA20150025A
Other languages
English (en)
Russian (ru)
Other versions
MD4383B1 (ro
Inventor
СТРАТУЛАТ Елена
Виорел ПРИСАКАРЬ
Михаил РЕВЕНКО
Анна ДИЗДАРЬ
Серджиу ШОВА
КОРЖА Ион
ПАЛАМАРЧУК Олег
Original Assignee
Государственный Университет Молд0
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Государственный Университет Молд0 filed Critical Государственный Университет Молд0
Priority to MDA20150025A priority Critical patent/MD4383C1/ro
Publication of MD4383B1 publication Critical patent/MD4383B1/ro
Publication of MD4383C1 publication Critical patent/MD4383C1/ro

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Abstract

Invenţia se referă la chimie şi medicină, şi anume la sinteza unui compus coordinativ nou al cuprului, biologic activ, din clasa tiosemicarbazonaţilor heterociclici, care poate găsi aplicare în medicină în calitate de preparat antimicrobian.Esenţa invenţiei constă în sinteza compusului acetato-(8-formilchinolintiosemicarbazo-no)cupru(II) cu formula:,care manifestă activitate antibacteriană faţă de bacteriile Staphylococcus aureus (tulpina 209-P), Enterococcus faecalis şi Proteus vulgaris.
MDA20150025A 2015-03-06 2015-03-06 Compusul acetato-(8-formilchinolintiosemicarbazono)cupru(II) care manifestă activitate antibacteriană MD4383C1 (ro)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20150025A MD4383C1 (ro) 2015-03-06 2015-03-06 Compusul acetato-(8-formilchinolintiosemicarbazono)cupru(II) care manifestă activitate antibacteriană

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20150025A MD4383C1 (ro) 2015-03-06 2015-03-06 Compusul acetato-(8-formilchinolintiosemicarbazono)cupru(II) care manifestă activitate antibacteriană

Publications (2)

Publication Number Publication Date
MD4383B1 MD4383B1 (ro) 2015-11-30
MD4383C1 true MD4383C1 (ro) 2016-06-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20150025A MD4383C1 (ro) 2015-03-06 2015-03-06 Compusul acetato-(8-formilchinolintiosemicarbazono)cupru(II) care manifestă activitate antibacteriană

Country Status (1)

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MD (1) MD4383C1 (ro)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985000955A1 (en) * 1983-08-22 1985-03-14 A/S Cheminova A biocidal, particularly fungicidal and/or bactericidal composition and thiosemicarbazones and metal complexes thereof for use in the composition
MD195B1 (ro) * 1994-12-05 1995-05-31 Univ De Stat De Medicina N Tes Complexurile cuprului cu proprietati antistafilococice
MD1650F1 (ro) * 1999-12-06 2001-04-30 Univ Nicolae Testemitanu 3,5-Dibromsalicilidentiosemicarbazidopiridincupru care manifesta activitate antistafilococica si antistreptococica
MD1812B1 (ro) * 2000-12-29 2001-12-31 Univ Nicolae Testemitanu Complecsi de cupru ca inhibitori de bacterii si fungi
MD2003B1 (ro) * 2001-01-10 2002-09-30 Univ Nicolae Testemitanu Complecsi interni de cupru(II) cu actiune antimicrobiana si antimicotica
MD2258B1 (ro) * 2001-10-04 2003-09-30 Univ Nicolae Testemitanu Complecsi chelatici ai cuprului (II) activi fata de microorganismele grampozitive
MD2942B2 (ro) * 2004-04-27 2005-12-31 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Di(µ-O)-bis(3,5-dibromsalicilidentiosemicarbazonatocupru)
MD4112B1 (ro) * 2010-05-17 2011-05-31 Univ De Stat Din Moldova Compuşi coordinativi ai cuprului cu 4-(dimetilfenil)-tiosemicarbazonele 2-formilpiridinei
MD4127B1 (ro) * 2010-10-06 2011-09-30 Univ De Stat Din Moldova Utilizare a di(µ-S)-bis{cloro-¢1-(piridin-2-il)etanon-4-metiltiosemicarbazonato(1-)]cupru} în calitate de substanţă cu activitate antimicrobiană faţă de Staphylococcus aureus
MD4258B1 (ro) * 2012-05-31 2013-11-30 Univ De Stat Din Moldova Utilizarea compusilor coordinativi ai cuprului(II) cu 4-(metoxifenil)tiosemicarbazonele 2-benzoilpiridinei în calitate de inhibitori ai Candida albicans

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985000955A1 (en) * 1983-08-22 1985-03-14 A/S Cheminova A biocidal, particularly fungicidal and/or bactericidal composition and thiosemicarbazones and metal complexes thereof for use in the composition
MD195B1 (ro) * 1994-12-05 1995-05-31 Univ De Stat De Medicina N Tes Complexurile cuprului cu proprietati antistafilococice
MD1650F1 (ro) * 1999-12-06 2001-04-30 Univ Nicolae Testemitanu 3,5-Dibromsalicilidentiosemicarbazidopiridincupru care manifesta activitate antistafilococica si antistreptococica
MD1812B1 (ro) * 2000-12-29 2001-12-31 Univ Nicolae Testemitanu Complecsi de cupru ca inhibitori de bacterii si fungi
MD2003B1 (ro) * 2001-01-10 2002-09-30 Univ Nicolae Testemitanu Complecsi interni de cupru(II) cu actiune antimicrobiana si antimicotica
MD2258B1 (ro) * 2001-10-04 2003-09-30 Univ Nicolae Testemitanu Complecsi chelatici ai cuprului (II) activi fata de microorganismele grampozitive
MD2942B2 (ro) * 2004-04-27 2005-12-31 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Di(µ-O)-bis(3,5-dibromsalicilidentiosemicarbazonatocupru)
MD4112B1 (ro) * 2010-05-17 2011-05-31 Univ De Stat Din Moldova Compuşi coordinativi ai cuprului cu 4-(dimetilfenil)-tiosemicarbazonele 2-formilpiridinei
MD4127B1 (ro) * 2010-10-06 2011-09-30 Univ De Stat Din Moldova Utilizare a di(µ-S)-bis{cloro-¢1-(piridin-2-il)etanon-4-metiltiosemicarbazonato(1-)]cupru} în calitate de substanţă cu activitate antimicrobiană faţă de Staphylococcus aureus
MD4258B1 (ro) * 2012-05-31 2013-11-30 Univ De Stat Din Moldova Utilizarea compusilor coordinativi ai cuprului(II) cu 4-(metoxifenil)tiosemicarbazonele 2-benzoilpiridinei în calitate de inhibitori ai Candida albicans

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Bourosh P., Revenco M., Stratulat E., Wicher B., Gdaniec M., Korzha I. Synthesis and structure of new copper(II) coordination compounds with 8-quinoline aldehyde semicarbazones and thiosemicarbazones. Russian Journal of Inorganic Chemistry, 2014, vol. 59 (6), p. 545-557 (regăsit în Internet la 2015.06.01 URL:<http://www.researchgate.net/publication/272013567_Synthesis_and_structure_of_new_copper%28II%29_coordination_compounds_with_8-quinoline_aldehyde_semicarbazones_and_thiosemicarbazones>) *
Revenco M., Bourosh P., Stratulat E., Gdaniec M., Lipkowski Ya., Korzha I. Synthesis and structure of copper(II) coordination compounds with 8-quinolinecarboxaldehyde thio- and 4-phenylthiosemicarbazones. Russian Journal of Inorganic Chemistry, 2010, vol. 55, nr. 9, p. 1387-1397 (regăsit în Internet la 2015.06.01 URL:<http://www.researchgate.net/publication/226036392_Synthesis_and_Structure_of_Copper%28II%29_Coordination_Compounds_with_8-Quinolinecarboxaldehyde_Thio-_and_4-Phenylthiosemicarbazones>) *
Revenko M., Prisacari V., Dizdari A., Stratulat E., Corja I., Proca L. Synthesis, antibacterial, and antifungal activities of 8-quinolinealdehyde chalcogensemicarbazones and their copper(II) complexes. Pharmaceutical Chemistry Journal, 2011, vol. 45, nr. 6, p. 351-354 (regăsit în Internet la 2015.06.03 URL:<http://www.researchgate.net/publication/235974189_ synthesis_antibacterial_and_antifungal_activities_of_8-quinolinealdehyde_chalcogensemicarbazones_and_their_copper%28ii%29_complexes>) *
Машковский М. Д. Лекарственные средства. Кишинэу, 1990, № 2, p. 264 *

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Publication number Publication date
MD4383B1 (ro) 2015-11-30

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KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees