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MD4383C1 - Соединение ацетато-(8-формилхинолинтиосемикарбазоно)медь(II), проявляющее антибактериальную активность - Google Patents

Соединение ацетато-(8-формилхинолинтиосемикарбазоно)медь(II), проявляющее антибактериальную активность

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Publication number
MD4383C1
MD4383C1 MDA20150025A MD20150025A MD4383C1 MD 4383 C1 MD4383 C1 MD 4383C1 MD A20150025 A MDA20150025 A MD A20150025A MD 20150025 A MD20150025 A MD 20150025A MD 4383 C1 MD4383 C1 MD 4383C1
Authority
MD
Moldova
Prior art keywords
copper
compound
formylquinolinethiosemicarbazono
acetato
antibacterial activity
Prior art date
Application number
MDA20150025A
Other languages
English (en)
Romanian (ro)
Other versions
MD4383B1 (ru
Inventor
СТРАТУЛАТ Елена
Виорел ПРИСАКАРЬ
Михаил РЕВЕНКО
Анна ДИЗДАРЬ
Серджиу ШОВА
КОРЖА Ион
ПАЛАМАРЧУК Олег
Original Assignee
Государственный Университет Молд0
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Государственный Университет Молд0 filed Critical Государственный Университет Молд0
Priority to MDA20150025A priority Critical patent/MD4383C1/ru
Publication of MD4383B1 publication Critical patent/MD4383B1/ru
Publication of MD4383C1 publication Critical patent/MD4383C1/ru

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Abstract

Изобретение относится к химии и медицине, а именно к синтезу нового биологически активного координационного соединения меди, класса гетероциклических тиосемикарбазонов, которое может найти применение в медицине в качестве антимикробного препарата.Сущностьизобретения заключается в синтезе соединения ацетато-(8-формилхинолинтиосемикарбазоно)медь(II) формулы:,проявляющего антибактериальную активность в отношении бактерий Staphylococcus aureus (штамм 209-P), Enterococcus faecalis и Proteus vulgaris.
MDA20150025A 2015-03-06 2015-03-06 Соединение ацетато-(8-формилхинолинтиосемикарбазоно)медь(II), проявляющее антибактериальную активность MD4383C1 (ru)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20150025A MD4383C1 (ru) 2015-03-06 2015-03-06 Соединение ацетато-(8-формилхинолинтиосемикарбазоно)медь(II), проявляющее антибактериальную активность

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20150025A MD4383C1 (ru) 2015-03-06 2015-03-06 Соединение ацетато-(8-формилхинолинтиосемикарбазоно)медь(II), проявляющее антибактериальную активность

Publications (2)

Publication Number Publication Date
MD4383B1 MD4383B1 (ru) 2015-11-30
MD4383C1 true MD4383C1 (ru) 2016-06-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20150025A MD4383C1 (ru) 2015-03-06 2015-03-06 Соединение ацетато-(8-формилхинолинтиосемикарбазоно)медь(II), проявляющее антибактериальную активность

Country Status (1)

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MD (1) MD4383C1 (ru)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985000955A1 (en) * 1983-08-22 1985-03-14 A/S Cheminova A biocidal, particularly fungicidal and/or bactericidal composition and thiosemicarbazones and metal complexes thereof for use in the composition
MD195B1 (ro) * 1994-12-05 1995-05-31 Univ De Stat De Medicina N Tes Complexurile cuprului cu proprietati antistafilococice
MD1650F1 (en) * 1999-12-06 2001-04-30 Univ Nicolae Testemitanu 3,5-Dibromsalicylidenethiosemicarbazidopyridinecopper possessing antistaphylococcia and antistreptococcia activity
MD1812B1 (en) * 2000-12-29 2001-12-31 Univ Nicolae Testemitanu Copper complexes as bacteria and fungi inhibitors
MD2003B1 (en) * 2001-01-10 2002-09-30 Univ Nicolae Testemitanu Copper chelate compounds(II) with antimicrobial and antimycotic activity
MD2258B1 (en) * 2001-10-04 2003-09-30 Univ Nicolae Testemitanu Chelating copper (II) complexes active in respect of gram-positive microorganisms
MD2942B2 (en) * 2004-04-27 2005-12-31 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Di(-O)-bis(3,5-dibromosalicylidene thiosemicarbazonatocopper)
MD4112B1 (en) * 2010-05-17 2011-05-31 Univ De Stat Din Moldova Coordinative compounds of copper with 4-(dimethylphenyl)-thiosemicarbazones of 2-formylpyridine
MD4127B1 (en) * 2010-10-06 2011-09-30 Univ De Stat Din Moldova Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus
MD4258B1 (en) * 2012-05-31 2013-11-30 Univ De Stat Din Moldova The use of biologically active coordinative compounds of copper(II) with 4-(methoxyphenyl)thiosemicarbazones of 2-benzoylpyridine as inhibitors of Candida albicans

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985000955A1 (en) * 1983-08-22 1985-03-14 A/S Cheminova A biocidal, particularly fungicidal and/or bactericidal composition and thiosemicarbazones and metal complexes thereof for use in the composition
MD195B1 (ro) * 1994-12-05 1995-05-31 Univ De Stat De Medicina N Tes Complexurile cuprului cu proprietati antistafilococice
MD1650F1 (en) * 1999-12-06 2001-04-30 Univ Nicolae Testemitanu 3,5-Dibromsalicylidenethiosemicarbazidopyridinecopper possessing antistaphylococcia and antistreptococcia activity
MD1812B1 (en) * 2000-12-29 2001-12-31 Univ Nicolae Testemitanu Copper complexes as bacteria and fungi inhibitors
MD2003B1 (en) * 2001-01-10 2002-09-30 Univ Nicolae Testemitanu Copper chelate compounds(II) with antimicrobial and antimycotic activity
MD2258B1 (en) * 2001-10-04 2003-09-30 Univ Nicolae Testemitanu Chelating copper (II) complexes active in respect of gram-positive microorganisms
MD2942B2 (en) * 2004-04-27 2005-12-31 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Di(-O)-bis(3,5-dibromosalicylidene thiosemicarbazonatocopper)
MD4112B1 (en) * 2010-05-17 2011-05-31 Univ De Stat Din Moldova Coordinative compounds of copper with 4-(dimethylphenyl)-thiosemicarbazones of 2-formylpyridine
MD4127B1 (en) * 2010-10-06 2011-09-30 Univ De Stat Din Moldova Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus
MD4258B1 (en) * 2012-05-31 2013-11-30 Univ De Stat Din Moldova The use of biologically active coordinative compounds of copper(II) with 4-(methoxyphenyl)thiosemicarbazones of 2-benzoylpyridine as inhibitors of Candida albicans

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Bourosh P., Revenco M., Stratulat E., Wicher B., Gdaniec M., Korzha I. Synthesis and structure of new copper(II) coordination compounds with 8-quinoline aldehyde semicarbazones and thiosemicarbazones. Russian Journal of Inorganic Chemistry, 2014, vol. 59 (6), p. 545-557 (regăsit în Internet la 2015.06.01 URL:<http://www.researchgate.net/publication/272013567_Synthesis_and_structure_of_new_copper%28II%29_coordination_compounds_with_8-quinoline_aldehyde_semicarbazones_and_thiosemicarbazones>) *
Revenco M., Bourosh P., Stratulat E., Gdaniec M., Lipkowski Ya., Korzha I. Synthesis and structure of copper(II) coordination compounds with 8-quinolinecarboxaldehyde thio- and 4-phenylthiosemicarbazones. Russian Journal of Inorganic Chemistry, 2010, vol. 55, nr. 9, p. 1387-1397 (regăsit în Internet la 2015.06.01 URL:<http://www.researchgate.net/publication/226036392_Synthesis_and_Structure_of_Copper%28II%29_Coordination_Compounds_with_8-Quinolinecarboxaldehyde_Thio-_and_4-Phenylthiosemicarbazones>) *
Revenko M., Prisacari V., Dizdari A., Stratulat E., Corja I., Proca L. Synthesis, antibacterial, and antifungal activities of 8-quinolinealdehyde chalcogensemicarbazones and their copper(II) complexes. Pharmaceutical Chemistry Journal, 2011, vol. 45, nr. 6, p. 351-354 (regăsit în Internet la 2015.06.03 URL:<http://www.researchgate.net/publication/235974189_ synthesis_antibacterial_and_antifungal_activities_of_8-quinolinealdehyde_chalcogensemicarbazones_and_their_copper%28ii%29_complexes>) *
Машковский М. Д. Лекарственные средства. Кишинэу, 1990, № 2, p. 264 *

Also Published As

Publication number Publication date
MD4383B1 (ru) 2015-11-30

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KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees