MA38930A1 - Anticorps, anti-récépteur du facteur de stimulation des colonies (csf1r) - Google Patents
Anticorps, anti-récépteur du facteur de stimulation des colonies (csf1r)Info
- Publication number
- MA38930A1 MA38930A1 MA38930A MA38930A MA38930A1 MA 38930 A1 MA38930 A1 MA 38930A1 MA 38930 A MA38930 A MA 38930A MA 38930 A MA38930 A MA 38930A MA 38930 A1 MA38930 A1 MA 38930A1
- Authority
- MA
- Morocco
- Prior art keywords
- antibody
- csf1r
- stimulating factor
- colony stimulating
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
Abstract
La présente invention concerne un anticorps anti-csf-1r et des fragments de liaison associés, de l'adn codant pour celui-ci, des cellules hôtes comportant ledit adn et des méthodes d'expression de l'anticorps ou d'un fragment de liaison dans une cellule hôte. La présente invention s'étend également à des compositions pharmaceutiques comprenant l'anticorps ou un fragment de liaison associé, et l'utilisation de l'anticorps, du fragment de liaison et des compositions les comprenant dans un traitement.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1315487.7A GB201315487D0 (en) | 2013-08-30 | 2013-08-30 | Antibodies |
PCT/EP2014/068050 WO2015028455A1 (fr) | 2013-08-30 | 2014-08-26 | Anticorps |
Publications (1)
Publication Number | Publication Date |
---|---|
MA38930A1 true MA38930A1 (fr) | 2017-12-29 |
Family
ID=49397073
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA44922A MA44922B1 (fr) | 2013-08-30 | 2014-08-26 | Anticorps |
MA38930A MA38930A1 (fr) | 2013-08-30 | 2014-08-26 | Anticorps, anti-récépteur du facteur de stimulation des colonies (csf1r) |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA44922A MA44922B1 (fr) | 2013-08-30 | 2014-08-26 | Anticorps |
Country Status (39)
Country | Link |
---|---|
US (2) | US9908939B2 (fr) |
EP (3) | EP3549599B1 (fr) |
JP (3) | JP6632075B2 (fr) |
KR (1) | KR102303130B1 (fr) |
CN (2) | CN105658236B (fr) |
AR (1) | AR097464A1 (fr) |
AU (1) | AU2014314304B2 (fr) |
BR (1) | BR112016004324B1 (fr) |
CA (1) | CA2922240C (fr) |
CL (1) | CL2016000438A1 (fr) |
CY (1) | CY1121964T1 (fr) |
DK (2) | DK3038643T3 (fr) |
EA (1) | EA036255B1 (fr) |
ES (2) | ES2965207T3 (fr) |
FI (1) | FI3549599T3 (fr) |
GB (1) | GB201315487D0 (fr) |
HK (1) | HK1220142A1 (fr) |
HR (2) | HRP20231264T1 (fr) |
HU (2) | HUE064437T2 (fr) |
IL (1) | IL244043B (fr) |
LT (2) | LT3038643T (fr) |
MA (2) | MA44922B1 (fr) |
MX (1) | MX2016002166A (fr) |
MY (1) | MY172484A (fr) |
NZ (1) | NZ717399A (fr) |
PE (2) | PE20160528A1 (fr) |
PH (1) | PH12016500275A1 (fr) |
PL (2) | PL3038643T3 (fr) |
PT (2) | PT3549599T (fr) |
RS (2) | RS59019B1 (fr) |
SG (1) | SG11201601151PA (fr) |
SI (2) | SI3038643T1 (fr) |
TN (1) | TN2016000067A1 (fr) |
TR (1) | TR201909478T4 (fr) |
TW (1) | TWI531582B (fr) |
UA (1) | UA118354C2 (fr) |
UY (1) | UY35718A (fr) |
WO (1) | WO2015028455A1 (fr) |
ZA (1) | ZA201601437B (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201315487D0 (en) * | 2013-08-30 | 2013-10-16 | Ucb Pharma Sa | Antibodies |
MY195000A (en) | 2015-05-27 | 2022-12-30 | Ucb Biopharma Sprl | Method for the treatment of neurological disease |
WO2016196679A1 (fr) * | 2015-06-02 | 2016-12-08 | Genentech, Inc. | Compositions et méthodes d'utilisation d'anticorps anti-il -34 pour traiter des maladies neurologiques |
KR102531889B1 (ko) | 2016-06-20 | 2023-05-17 | 키맵 리미티드 | 항-pd-l1 및 il-2 사이토카인 |
WO2018183366A1 (fr) | 2017-03-28 | 2018-10-04 | Syndax Pharmaceuticals, Inc. | Polythérapies d'anticorps csf-1r ou csf-1 et thérapie reposant sur des lymphocytes t |
KR102651568B1 (ko) * | 2017-05-19 | 2024-03-25 | 신닥스 파마슈티컬스, 인크. | 조합 요법 |
GB201803226D0 (en) * | 2018-02-28 | 2018-04-11 | Ultrahuman Twelve Ltd | CSF1R Binding agents |
CN108948198B (zh) * | 2018-07-18 | 2020-09-01 | 博奥信生物技术(南京)有限公司 | 抗人csf-1r单克隆抗体及其应用 |
CN109096397B (zh) * | 2018-07-18 | 2019-04-16 | 博奥信生物技术(南京)有限公司 | 一种抗人csf-1r单克隆抗体及应用 |
TWI733274B (zh) | 2018-12-13 | 2021-07-11 | 財團法人生物技術開發中心 | 抗人類csf-1r抗體及其用途 |
CN113939539B (zh) * | 2019-05-15 | 2024-06-04 | 博奥信生物技术(南京)有限公司 | 结合csf-1r的抗体及其用途 |
WO2021119128A1 (fr) * | 2019-12-09 | 2021-06-17 | Syndax Pharmaceuticals, Inc. | Anticorps pour le traitement d'une maladie chronique du greffon contre l'hôte |
EP4081255A4 (fr) * | 2019-12-24 | 2024-04-03 | Adagene (Suzhou) Limited | Molécules anti-csf1r et utilisation correspondante |
Family Cites Families (46)
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US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
DK336987D0 (da) | 1987-07-01 | 1987-07-01 | Novo Industri As | Immobiliseringsmetode |
GB8719042D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
GB8907617D0 (en) | 1989-04-05 | 1989-05-17 | Celltech Ltd | Drug delivery system |
GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
CA2090126C (fr) | 1990-08-02 | 2002-10-22 | John W. Schrader | Methodes de production de proteines dotees d'une fonction desiree |
GB9112536D0 (en) | 1991-06-11 | 1991-07-31 | Celltech Ltd | Chemical compounds |
GB9113120D0 (en) | 1991-06-18 | 1991-08-07 | Kodak Ltd | Photographic processing apparatus |
GB9120467D0 (en) | 1991-09-26 | 1991-11-06 | Celltech Ltd | Anti-hmfg antibodies and process for their production |
FR2716640B1 (fr) | 1994-02-28 | 1996-05-03 | Procedes Machines Speciales | Dispositif de centrage et de blocage d'une pièce en vue de son rodage à l'aide d'un rodoir à expansion. |
US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
GB9625640D0 (en) | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
GB9812545D0 (en) | 1998-06-10 | 1998-08-05 | Celltech Therapeutics Ltd | Biological products |
US6908963B2 (en) | 2001-10-09 | 2005-06-21 | Nektar Therapeutics Al, Corporation | Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith |
GB0129105D0 (en) | 2001-12-05 | 2002-01-23 | Celltech R&D Ltd | Expression control using variable intergenic sequences |
PT1570267E (pt) | 2002-12-03 | 2012-01-03 | Ucb Pharma Sa | Ensaio para a identificação de células produtoras de anticorpos |
GB0312481D0 (en) | 2003-05-30 | 2003-07-09 | Celltech R&D Ltd | Antibodies |
GB0315457D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
SI1644412T2 (sl) | 2003-07-01 | 2018-11-30 | Ucb Biopharma Sprl | Modificirani fab fragmenti protiteles |
GB0315450D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
WO2005014655A2 (fr) | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugues d'amidon d'hydroxyalkyle et de proteine |
AR045563A1 (es) * | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
GB0411186D0 (en) | 2004-05-19 | 2004-06-23 | Celltech R&D Ltd | Biological products |
GB0412181D0 (en) | 2004-06-01 | 2004-06-30 | Celltech R&D Ltd | Biological products |
MY146381A (en) * | 2004-12-22 | 2012-08-15 | Amgen Inc | Compositions and methods relating relating to anti-igf-1 receptor antibodies |
GB0619291D0 (en) | 2006-09-29 | 2006-11-08 | Ucb Sa | Altered antibodies |
JP5718640B2 (ja) | 2007-08-21 | 2015-05-13 | アムジエン・インコーポレーテツド | ヒトc−fms抗原結合性タンパク質 |
JP5592792B2 (ja) | 2007-09-26 | 2014-09-17 | ユセベ ファルマ ソシエテ アノニム | 二重特異性抗体の融合体 |
JO3240B1 (ar) * | 2007-10-17 | 2018-03-08 | Janssen Pharmaceutica Nv | c-fms مثبطات كيناز |
JP5805393B2 (ja) | 2008-03-14 | 2015-11-04 | トランジェーヌ、ソシエテ、アノニムTransgene S.A. | Csf−1rに対する抗体 |
US8470977B2 (en) * | 2008-03-14 | 2013-06-25 | Transgene S.A. | Antibody against the CSF-1R |
WO2010035012A1 (fr) | 2008-09-26 | 2010-04-01 | Ucb Pharma S.A. | Produits biologiques |
EP2475682B1 (fr) | 2009-09-10 | 2018-01-31 | UCB Biopharma SPRL | Anticorps multivalents |
GB0920127D0 (en) | 2009-11-17 | 2009-12-30 | Ucb Pharma Sa | Antibodies |
BR112012013717B1 (pt) * | 2009-12-10 | 2020-01-28 | Hoffmann La Roche | anticorpos de ligação ao csf-1r humano, composição farmacêutica e usos do anticorpo |
GB201000467D0 (en) | 2010-01-12 | 2010-02-24 | Ucb Pharma Sa | Antibodies |
CN102918060B (zh) | 2010-03-05 | 2016-04-06 | 霍夫曼-拉罗奇有限公司 | 抗人csf-1r抗体及其用途 |
JP5989547B2 (ja) * | 2010-03-05 | 2016-09-07 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | ヒトcsf−1rに対する抗体及びその使用 |
AR080698A1 (es) * | 2010-04-01 | 2012-05-02 | Imclone Llc | Anticuerpo o fragmento del mismo que especificamente enlaza la variante de csf -1r humano, composicion farmaceutica que lo comprende, su uso para la manufactura de un medicamento util para el tratamiento de cancer y metodo para determinar si un sujeto es candidato para tratamiento de cancer basado e |
AU2011248083B2 (en) | 2010-05-04 | 2015-09-10 | Five Prime Therapeutics, Inc. | Antibodies that bind CSF1R |
MX356337B (es) | 2011-12-15 | 2018-05-23 | Hoffmann La Roche | Anticuerpos contra csf-1r humano y sus usos. |
GB201315486D0 (en) | 2013-08-30 | 2013-10-16 | Ucb Pharma Sa | Antibodies |
GB201315487D0 (en) * | 2013-08-30 | 2013-10-16 | Ucb Pharma Sa | Antibodies |
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2013
- 2013-08-30 GB GBGB1315487.7A patent/GB201315487D0/en not_active Ceased
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2014
- 2014-08-05 TW TW103126815A patent/TWI531582B/zh active
- 2014-08-26 EP EP19171833.7A patent/EP3549599B1/fr active Active
- 2014-08-26 PT PT191718337T patent/PT3549599T/pt unknown
- 2014-08-26 LT LTEP14755668.2T patent/LT3038643T/lt unknown
- 2014-08-26 TN TN2016000067A patent/TN2016000067A1/en unknown
- 2014-08-26 CN CN201480057403.8A patent/CN105658236B/zh active Active
- 2014-08-26 SG SG11201601151PA patent/SG11201601151PA/en unknown
- 2014-08-26 ES ES19171833T patent/ES2965207T3/es active Active
- 2014-08-26 DK DK14755668.2T patent/DK3038643T3/da active
- 2014-08-26 MX MX2016002166A patent/MX2016002166A/es active IP Right Grant
- 2014-08-26 WO PCT/EP2014/068050 patent/WO2015028455A1/fr active Application Filing
- 2014-08-26 SI SI201431235T patent/SI3038643T1/sl unknown
- 2014-08-26 PL PL14755668T patent/PL3038643T3/pl unknown
- 2014-08-26 RS RS20190833A patent/RS59019B1/sr unknown
- 2014-08-26 US US14/914,676 patent/US9908939B2/en active Active
- 2014-08-26 MA MA44922A patent/MA44922B1/fr unknown
- 2014-08-26 PT PT14755668T patent/PT3038643T/pt unknown
- 2014-08-26 PE PE2016000313A patent/PE20160528A1/es unknown
- 2014-08-26 BR BR112016004324-3A patent/BR112016004324B1/pt active IP Right Grant
- 2014-08-26 MA MA38930A patent/MA38930A1/fr unknown
- 2014-08-26 ES ES14755668T patent/ES2733735T3/es active Active
- 2014-08-26 HU HUE19171833A patent/HUE064437T2/hu unknown
- 2014-08-26 PL PL19171833.7T patent/PL3549599T3/pl unknown
- 2014-08-26 RS RS20230962A patent/RS64784B1/sr unknown
- 2014-08-26 NZ NZ717399A patent/NZ717399A/en unknown
- 2014-08-26 FI FIEP19171833.7T patent/FI3549599T3/fi active
- 2014-08-26 JP JP2016537262A patent/JP6632075B2/ja active Active
- 2014-08-26 TR TR2019/09478T patent/TR201909478T4/tr unknown
- 2014-08-26 LT LTEP19171833.7T patent/LT3549599T/lt unknown
- 2014-08-26 EA EA201690503A patent/EA036255B1/ru not_active IP Right Cessation
- 2014-08-26 PE PE2020000532A patent/PE20201067A1/es unknown
- 2014-08-26 MY MYPI2016700624A patent/MY172484A/en unknown
- 2014-08-26 DK DK19171833.7T patent/DK3549599T5/da active
- 2014-08-26 EP EP23192221.2A patent/EP4282881A3/fr active Pending
- 2014-08-26 HU HUE14755668A patent/HUE045672T2/hu unknown
- 2014-08-26 KR KR1020167007073A patent/KR102303130B1/ko active IP Right Grant
- 2014-08-26 AU AU2014314304A patent/AU2014314304B2/en active Active
- 2014-08-26 SI SI201432048T patent/SI3549599T1/sl unknown
- 2014-08-26 CA CA2922240A patent/CA2922240C/fr active Active
- 2014-08-26 CN CN202011009068.8A patent/CN112321711B/zh active Active
- 2014-08-26 HR HRP20231264TT patent/HRP20231264T1/hr unknown
- 2014-08-26 EP EP14755668.2A patent/EP3038643B1/fr active Active
- 2014-08-26 UA UAA201601175A patent/UA118354C2/uk unknown
- 2014-08-27 AR ARP140103206A patent/AR097464A1/es unknown
- 2014-08-29 UY UY35718A patent/UY35718A/es not_active Application Discontinuation
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2016
- 2016-02-09 IL IL244043A patent/IL244043B/en active IP Right Grant
- 2016-02-10 PH PH12016500275A patent/PH12016500275A1/en unknown
- 2016-02-25 CL CL2016000438A patent/CL2016000438A1/es unknown
- 2016-03-02 ZA ZA2016/01437A patent/ZA201601437B/en unknown
- 2016-07-15 HK HK16108335.9A patent/HK1220142A1/zh unknown
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2018
- 2018-01-30 US US15/883,130 patent/US10421814B2/en active Active
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2019
- 2019-06-12 HR HRP20191051TT patent/HRP20191051T1/hr unknown
- 2019-07-23 CY CY20191100779T patent/CY1121964T1/el unknown
- 2019-09-13 JP JP2019166697A patent/JP7195237B2/ja active Active
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2021
- 2021-09-17 JP JP2021152574A patent/JP2022002523A/ja active Pending
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