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Seitan et al., 2006 - Google Patents

Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance

Seitan et al., 2006

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Document ID
2457569541795508800
Author
Seitan V
Banks P
Laval S
Majid N
Dorsett D
Rana A
Smith J
Bateman A
Krpic S
Hostert A
Rollins R
Erdjument-Bromage H
Tempst P
Benard C
Hekimi S
Newbury S
Strachan T
Publication year
Publication venue
PLoS biology

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Snippet

Saccharomyces cerevisiae Scc2 binds Scc4 to form an essential complex that loads cohesin onto chromosomes. The prevalence of Scc2 orthologs in eukaryotes emphasizes a conserved role in regulating sister chromatid cohesion, but homologs of Scc4 have not …
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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