Ibarra-Morales et al., 2021 - Google Patents
Histone variant H2A. Z regulates zygotic genome activationIbarra-Morales et al., 2021
View HTML- Document ID
- 18031709781632250453
- Author
- Ibarra-Morales D
- Rauer M
- Quarato P
- Rabbani L
- Zenk F
- Schulte-Sasse M
- Cardamone F
- Gomez-Auli A
- Cecere G
- Iovino N
- Publication year
- Publication venue
- Nature communications
External Links
Snippet
During embryogenesis, the genome shifts from transcriptionally quiescent to extensively active in a process known as Zygotic Genome Activation (ZGA). In Drosophila, the pioneer factor Zelda is known to be essential for the progression of development; still, it regulates the …
- 230000004913 activation 0 title abstract description 25
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6802—General aspects
- C12Q1/6809—Sequence identification involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Ibarra-Morales et al. | Histone variant H2A. Z regulates zygotic genome activation | |
Knuckles et al. | Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl (2) d | |
Hartford et al. | When long noncoding becomes protein coding | |
Kan et al. | A neural m6A/Ythdf pathway is required for learning and memory in Drosophila | |
Andersen et al. | A heterochromatin-dependent transcription machinery drives piRNA expression | |
Criscione et al. | The chromatin landscape of cellular senescence | |
Zhang et al. | Dynamic FMR1 granule phase switch instructed by m6A modification contributes to maternal RNA decay | |
Seitan et al. | Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance | |
Ortabozkoyun et al. | CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters | |
Sun et al. | Quantitative proteomics of Xenopus laevis embryos: expression kinetics of nearly 4000 proteins during early development | |
Ratnakumar et al. | ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression | |
Yang et al. | ncRNA-and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs | |
Basu et al. | YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment | |
Gelbart et al. | Drosophila dosage compensation: a complex voyage to the X chromosome | |
Neumüller et al. | Conserved regulators of nucleolar size revealed by global phenotypic analyses | |
Li et al. | The histone modification reader ZCWPW1 is required for meiosis prophase I in male but not in female mice | |
Bonnet et al. | Quantification of proteins and histone marks in Drosophila embryos reveals stoichiometric relationships impacting chromatin regulation | |
González-Aguilera et al. | Genome-wide analysis links emerin to neuromuscular junction activity in Caenorhabditis elegans | |
Yang et al. | The chaperone Tsr2 regulates Rps26 release and reincorporation from mature ribosomes to enable a reversible, ribosome-mediated response to stress | |
He et al. | 6mA-DNA-binding factor Jumu controls maternal-to-zygotic transition upstream of Zelda | |
Carrasco et al. | ELAV and FNE determine neuronal transcript signatures through EXon-activated rescue | |
Regadas et al. | A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation | |
Delaney et al. | Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65 | |
Takahashi et al. | The role of Mediator and Little Elongation Complex in transcription termination | |
Hadžić et al. | Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED |