Katona et al., 2011 - Google Patents
Distinct pathogenic processes between Fig4‐deficient motor and sensory neuronsKatona et al., 2011
- Document ID
- 18387021279353903382
- Author
- Katona I
- Zhang X
- Bai Y
- Shy M
- Guo J
- Yan Q
- Hatfield J
- Kupsky W
- Li J
- Publication year
- Publication venue
- European Journal of Neuroscience
External Links
Snippet
Loss of function of the FIG4 gene causes Charcot‐Marie‐Tooth disease (CMT)‐4J with many features also found in motor neuron disease (MND). Mechanisms for the degeneration are unknown. We investigated this using Fig4‐deficient pale tremor (plt) mice, a mouse model of …
- 101700019037 FIG4 0 title abstract description 57
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- G—PHYSICS
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- G01N33/5058—Neurological cells
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- A61K31/33—Heterocyclic compounds
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- G—PHYSICS
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