OR2H2

OR2H2
Identifiers
Aliases	OR2H2, FAT11, OLFR2, OLFR42B, OR2H3, dJ271M21.2, hs6M1-12, olfactory receptor family 2 subfamily H member 2
External IDs	OMIM: 600578; MGI: 2177473; HomoloGene: 68546; GeneCards: OR2H2; OMA:OR2H2 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.1 Start 29,585,121 bp[1] End 29,590,500 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 B1 Start 37,394,763 bp[2] End 37,399,391 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle putamen nucleus accumbens caudate nucleus right hemisphere of cerebellum ventricular zone temporal lobe amygdala hippocampus proper anterior cingulate cortex Top expressed in embryo blastocyst bone marrow conceptus female reproductive system placenta More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process defense response mating signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7932 258469 Ensembl ENSG00000204657 ENSMUSG00000056600 UniProt O95918 n/a RefSeq (mRNA) NM_007160 NM_146477 RefSeq (protein) NP_009091 n/a Location (UCSC) Chr 6: 29.59 – 29.59 Mb Chr 17: 37.39 – 37.4 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 2H2 is a protein that in humans is encoded by the OR2H2 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

• Olfactory receptor

• OR2H2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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