OR7A5

OR7A5
Identifiers
Aliases	OR7A5, HTPCR2, olfactory receptor family 7 subfamily A member 5
External IDs	MGI: 1333808; HomoloGene: 133620; GeneCards: OR7A5; OMA:OR7A5 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.12 Start 14,826,241 bp[1] End 14,835,185 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 C1 Start 78,864,575 bp[2] End 78,872,108 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in inferior olivary nucleus C1 segment corpus epididymis substantia nigra pituitary gland anterior pituitary caput epididymis skin of leg inferior ganglion of vagus nerve internal globus pallidus Top expressed in lung embryo spermatid mesencephalon More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26659 18357 Ensembl ENSG00000188269 ENSMUSG00000060205 UniProt Q15622 Q8VGU7 RefSeq (mRNA) NM_017506 NM_001370480 NM_001370481 NM_001370482 NM_001370483 NM_147041 RefSeq (protein) NP_059976 NP_001357409 NP_001357410 NP_001357411 NP_001357412 NP_667252 Location (UCSC) Chr 19: 14.83 – 14.84 Mb Chr 10: 78.86 – 78.87 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 7A5 is a protein that in humans is encoded by the OR7A5 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

• Olfactory receptor

• OR7A5+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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