Physics of Living Systems

Physics of Living Systems

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Physics of Living Systems

    A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

    David Trombley McSwiggen, Helen Liu ... Hilary P Beck
    Single-molecule tracking at scale, analyzing millions of cells and thousands of compounds per day, demonstrates that measuring protein motion provides mechanistic insights relevant to drug discovery.
    1. Neuroscience
    2. Physics of Living Systems

    The Geometry and Dimensionality of Brain-wide Activity

    Zezhen Wang, Weihao Mai ... Quan Wen
    Not revised
    Reviewed Preprint v1
    1. Neuroscience
    2. Physics of Living Systems

    Wavenumber-dependent transmission of subthreshold waves on electrical synapses network model of Caenorhabditis elegans

    Iksoo Chang, Taegon Chung, Sangyeol Kim
    The composition of nodes that effectively transmit sinusoidal waves in a model network resembling C. elegans' electrical synapses network changes according to the waves' wavenumber.
    1. Physics of Living Systems

    Toward Stable Replication of Genomic Information in Pools of RNA Molecules

    Ludwig Burger, Ulrich Gerland
    Not revised
    Reviewed Preprint v1
    1. Cell Biology
    2. Physics of Living Systems

    A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits

    Krishna Rijal, Pankaj Mehta
    Not revised
    Reviewed Preprint v1
    1. Neuroscience
    2. Physics of Living Systems

    Advantageous and disadvantageous inequality aversion can be taught through vicarious learning of others’ preferences

    Shen Zhang, Oriel FeldmanHall ... A Ross Otto
    Not revised
    Reviewed Preprint v1
    1. Physics of Living Systems

    Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws

    M Julia Maristany, Anne Aguirre Gonzalez ... Jerelle A Joseph
    Revised
    Reviewed Preprint v2
    Updated
    1. Physics of Living Systems

    The eduWOSM: a benchtop advanced microscope for education and research

    Nicholas J Carter, Douglas S Martin ... Robert A Cross
    Not revised
    Reviewed Preprint v1
    1. Cell Biology
    2. Physics of Living Systems

    Mechanical imbalance between normal and transformed cells drives epithelial homeostasis through cell competition

    Praver Gupta, Sayantani Kayal ... Tamal Das
    Not revised
    Reviewed Preprint v1
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    Cluster size determines morphology of transcription factories in human cells

    Massimiliano Semeraro, Giuseppe Negro ... Davide Marenduzzo
    Not revised
    Reviewed Preprint v1
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Highlights

    1. Physics of Living Systems

    Flagella: A new kind of beat

    Kirsty Y Wan
    1. Physics of Living Systems

    Cancer: Cells under pressure

    Dhiraj Indana, Ovijit Chaudhuri
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Modelling biomolecular condensates

    Furqan Dar, Rohit Pappu

Senior editors

  1. Felix Campelo
    The Institute of Photonic Sciences, Spain
  2. Aleksandra Walczak
    Ecole Normale Superieure, France
  3. See more editors