Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Immunology and Inflammation

    Autoimmunity: The epigenetic trajectory of type 1 regulatory T cells

    David P Turicek, Xiaoxiao Wan
    The epigenome of T follicular helper cells prepares them for conversion into type 1 regulatory T cells.
    Version of Record
    Insight
    1. Developmental Biology

    Neuronal Development: Rethinking sensorimotor circuits

    Maarten F Zwart
    New research shows that the neural circuit responsible for stabilising gaze can develop in the absence of motor neurons, contrary to a long-standing model in the field.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    Gut Microbes: Regulating uric acid

    Caihong Hu
    Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum, are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.
    Version of Record
    Insight
    1. Cancer Biology
    2. Genetics and Genomics

    Cancer: Predicting drug resistance

    Nicole S Arellano, Shannon E Elf
    A new approach helps examine the proportion of cancerous and healthy stem cells in patients with chronic myeloid leukemia and how this influences treatment outcomes.
    Version of Record
    Insight
    1. Stem Cells and Regenerative Medicine

    Cell Death: Caspases promote cell proliferation after necrosis

    Prathibha Yarikipati, Andreas Bergmann
    An enzyme known as caspase, which initiates apoptosis, has a central role in the regeneration of cells and repair of tissue that can occur after necrosis.
    Version of Record
    Insight
    1. Stem Cells and Regenerative Medicine

    Notch Signaling: Antibodies get under the skin

    Chiara Levra Levron, Gabriele Piacenti, Giacomo Donati
    By inhibiting receptor-ligand interactions in sebaceous glands, antibodies may be able to treat certain skin conditions.
    Version of Record
    Insight
    1. Stem Cells and Regenerative Medicine

    Immune Cells: Growing microglia in the lab

    Jonathan M Levenson, Hio Tong Kam, Dong Feng Chen
    Transplanting microglia derived from human stem cells into mice reveals new possibilities for treating neurodegenerative eye diseases.
    Version of Record
    Insight
    1. Ecology
    2. Evolutionary Biology

    Camouflage: Tiny particles help insects evade predators

    Lin Wang, Tak-Sing Wong
    By reducing the reflection of ultraviolet light, hollow nanoparticles called brochosomes help to protect leafhoppers from predators.
    Version of Record
    Insight
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Stem Cells: Don’t be so naïve

    Valerie Horsley, Aya Nassereddine
    New evidence sheds light on actin regulation of pluripotency in human embryonic stem cells.
    Version of Record
    Insight
    1. Neuroscience

    Decisions: Tracking the evolution of a single choice

    Bharath Chandra Talluri, Hendrikje Nienborg
    Measuring the activity of hundreds of neurons in macaque brains simultaneously provides further evidence that drift-diffusion dynamics underlie how decisions are made in the brain.
    Version of Record
    Insight