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Robert R. Freimuth

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2020 – today

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2024
[j23]
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Nephi A. Walton, Radhakrishnan Nagarajan, Chen Wang, Murat Sincan, Robert R. Freimuth, David B. Everman, Derek C. Walton, Scott P. McGrath, Dominick J. Lemas, Panayiotis V. Benos, Alexander V. Alekseyenko, Qianqian Song, Ece D. Gamsiz Uzun, Casey Overby Taylor, Alper Uzun, Thomas N. Person, Nadav Rappoport, Zhongming Zhao, Marc S. Williams:
Enabling the clinical application of artificial intelligence in genomics: a perspective of the AMIA Genomics and Translational Bioinformatics Workgroup. J. Am. Medical Informatics Assoc. 31(2): 536-541 (2024)
2023
[c22]
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Aly Khalifa, Robert R. Freimuth:
Representing NIH Genetic Test Registry Data in the FHIR Genomic Study Resource. ICIMTH 2023: 398-401
2022
[j22]
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Yiqing Zhao, Matthew Brush, Chen Wang, Alex H. Wagner, Hongfang Liu, Robert R. Freimuth:
Leveraging a pharmacogenomics knowledgebase to formulate a drug response phenotype terminology for genomic medicine. Bioinform. 38(23): 5279-5287 (2022)
[j21]
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Ken Wiley, Laura Findley, Madison Goldrich, Tejinder K. Rakhra-Burris, Ana Stevens, Pamela Williams, Carol J. Bult, Rex L. Chisholm, Patricia Deverka, Geoffrey S. Ginsburg, Eric D. Green, Gail P. Jarvik, George A. Mensah, Erin Ramos, Mary V. Relling, Dan M. Roden, Robb Rowley, Gil Alterovitz, Samuel J. Aronson, Lisa Bastarache, James J. Cimino, Erin L. Crowgey, Guilherme Del Fiol, Robert R. Freimuth, Mark A. Hoffman, Janina M. Jeff, Kevin B. Johnson, Kensaku Kawamoto, Subha Madhavan, Eneida A. Mendonça, Lucila Ohno-Machado, Siddharth Pratap, Casey Overby Taylor, Marylyn D. Ritchie, Nephi Walton, Chunhua Weng, Teresa Zayas-Cabán, Teri A. Manolio, Marc S. Williams:
A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources. J. Am. Medical Informatics Assoc. 29(8): 1342-1349 (2022)
[j20]
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Jingzhi Yu, Jennifer A. Pacheco, Anika S. Ghosh, Yuan Luo, Chunhua Weng, Ning Shang, Barbara Benoit, David S. Carrell, Robert J. Carroll, Ozan Dikilitas, Robert R. Freimuth, Vivian S. Gainer, Hakon Hakonarson, George Hripcsak, Iftikhar J. Kullo, Frank D. Mentch, Shawn N. Murphy, Peggy L. Peissig, Andrea H. Ramirez, Nephi Walton, Wei-Qi Wei, Luke V. Rasmussen:
Under-specification as the source of ambiguity and vagueness in narrative phenotype algorithm definitions. BMC Medical Informatics Decis. Mak. 22(1): 23 (2022)
2021
[j19]
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Luke V. Rasmussen, John J. Connolly, Guilherme Del Fiol, Robert R. Freimuth, Douglas B. Pet, Josh F. Peterson, Brian H. Shirts, Justin B. Starren, Marc S. Williams, Nephi Walton, Casey Overby Taylor:
Infobuttons for Genomic Medicine: Requirements and Barriers. Appl. Clin. Inform. 12(02): 383-390 (2021)
[j18]
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Carolyn Petersen, Jeffery Smith, Robert R. Freimuth, Kenneth W. Goodman, Gretchen Purcell Jackson, Joseph L. Kannry, Hongfang Liu, Subha Madhavan, Dean F. Sittig, Adam Wright:
Recommendations for the safe, effective use of adaptive CDS in the US healthcare system: an AMIA position paper. J. Am. Medical Informatics Assoc. 28(4): 677-684 (2021)
[j17]
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Mullai Murugan, Lawrence J. Babb, Casey Overby Taylor, Luke V. Rasmussen, Robert R. Freimuth, Eric Venner, Fei Yan, Victoria Yi, Stephen J. Granite, Hana Zouk, Samuel J. Aronson, Kevin Power, Alexander Fedotov, David R. Crosslin, David Fasel, Gail P. Jarvik, Hakon Hakonarson, Hana Bangash, Iftikhar J. Kullo, John J. Connolly, Jordan G. Nestor, Pedro J. Caraballo, Wei-Qi Wei, Ken Wiley, Heidi L. Rehm, Richard A. Gibbs:
Genomic considerations for FHIR®; eMERGE implementation lessons. J. Biomed. Informatics 118: 103795 (2021)
[c21]
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Jane L. Shellum, Davide Sottara, Robert R. Freimuth, Aaron Nathan, Adam M. Bartscher:
Content in Context - Individualizing Knowledge Resources for Delivery at the Point of Care. AMIA 2021
[c20]
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Alex H. Wagner, Lawrence J. Babb, Melissa S. Cline, Helen Schuilenburg, Tristan Nelson, Robert R. Freimuth, Reece Hart:
The GA4GH Variation Representation Specification (VRS): a Computational Framework for the Precise Representation of Molecular Variation. AMIA 2021
[c19]
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Yiqing Zhao, Matthew Brush, Hongfang Liu, Robert R. Freimuth:
Modeling Variant Annotation (VA) Therapeutic Association Statements using a SEPIO-Based Workflow. AMIA 2021
2020
[j16]
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Stephanie J. Garcia, Teresa Zayas-Cabán, Robert R. Freimuth:
Sync for Genes: Making Clinical Genomics Available for Precision Medicine at the Point-of-Care. Appl. Clin. Inform. 11(02): 295-302 (2020)

2010 – 2019

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2019
[c18]
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Stephanie Garcia, Robert R. Freimuth, David E. Jones, Robert P. Milius:
Sync for Genes: Integrating Genetic Information at the Point of Care. AMIA 2019
[c17]
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Branden C. Hickey, Adam M. Bartscher, Marc Sainvil, Robert R. Freimuth, Jane L. Shellum, Davide Sottara:
Automated Extraction of Computable Clinical Decision Support Rules from an Electronic Health Record (EHR) System. AMIA 2019
2018
[j15]
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Samuel J. Aronson, Lawrence J. Babb, Darren C. Ames, Richard A. Gibbs, Eric Venner, John J. Connelly, Keith Marsolo, Chunhua Weng, Marc S. Williams, Andrea L. Hartzler, Wayne H. Liang, James D. Ralston, Emily Beth Devine, Shawn N. Murphy, Christopher G. Chute, Pedro J. Caraballo, Iftikhar J. Kullo, Robert R. Freimuth, Luke V. Rasmussen, Firas H. Wehbe, Josh F. Peterson, Jamie R. Robinson, Ken Wiley, Casey Overby Taylor, eMERGE Network EHRI Working Group:
Empowering genomic medicine by establishing critical sequencing result data flows: the eMERGE example. J. Am. Medical Informatics Assoc. 25(10): 1375-1381 (2018)
[c16]
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Shashwat Nagar, Richard C. Kiefer, Robert R. Freimuth:
A Scalable Encoding Scheme for Clinical Genomic Results Delivered Through Web Services and a Mobile Application. AMIA 2018
2017
[c15]
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Ali Hasnie, Pedro J. Caraballo, Robert R. Freimuth, Iftikhar J. Kullo:
Development & Implementation of a Clinical Decision Support Tool for Familial Hypercholesterolemia. AMIA 2017
2016
[j14]
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Casey L. Overby, Guilherme Del Fiol, Wendy S. Rubinstein, Donna R. Maglott, Tristan Nelson, Aleksandar Milosavljevic, Christa Martin, Scott Goehringer, Robert R. Freimuth, Marc S. Williams, Bret S. E. Heale:
Integrating Genomic Resources with Electronic Health Records using the HL7 Infobutton Standard. Appl. Clin. Inform. 07(03): 817-831 (2016)
[j13]
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Casey L. Overby, John J. Connolly, Christopher G. Chute, Joshua C. Denny, Robert R. Freimuth, Andrea L. Hartzler, Ingrid A. Holm, Shannon F. Manzi, Jyotishman Pathak, Peggy L. Peissig, Maureen E. Smith, Marc S. Williams, Brian H. Shirts, Elena M. Stoffel, Peter Tarczy-Hornoch, Carolyn Rohrer Vitek, Wendy A. Wolf, Justin Starren, Luke V. Rasmussen:
Practical considerations for implementing genomic information resources. Appl. Clin. Inform. 07(03): 870-882 (2016)
[j12]
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Laura K. Wiley, Peter Tarczy-Hornoch, Joshua C. Denny, Robert R. Freimuth, Casey L. Overby, Nigam Shah, Ross D. Martin, Indra Neil Sarkar:
Harnessing next-generation informatics for personalizing medicine: a report from AMIA's 2014 Health Policy Invitational Meeting. J. Am. Medical Informatics Assoc. 23(2): 413-419 (2016)
[j11]
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Jessica D. Tenenbaum, Paul Avillach, Marge M. Benham-Hutchins, Matthew K. Breitenstein, Erin L. Crowgey, Mark A. Hoffman, Xia Jiang, Subha Madhavan, John E. Mattison, Radhakrishnan Nagarajan, Bisakha Ray, Dmitriy Shin, Shyam Visweswaran, Zhongming Zhao, Robert R. Freimuth:
An informatics research agenda to support precision medicine: seven key areas. J. Am. Medical Informatics Assoc. 23(4): 791-795 (2016)
[j10]
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James M. Hoffman, Henry M. Dunnenberger, J. Kevin Hicks, Kelly E. Caudle, Michelle Whirl Carrillo, Robert R. Freimuth, Marc S. Williams, Teri E. Klein, Josh F. Peterson:
Developing knowledge resources to support precision medicine: principles from the Clinical Pharmacogenetics Implementation Consortium (CPIC). J. Am. Medical Informatics Assoc. 23(4): 796-801 (2016)
[j9]
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Ayesha Aziz, Kensaku Kawamoto, Karen Eilbeck, Marc S. Williams, Robert R. Freimuth, Mark A. Hoffman, Luke V. Rasmussen, Casey Lynnette Overby, Brian H. Shirts, James M. Hoffman, Brandon M. Welch:
The genomic CDS sandbox: An assessment among domain experts. J. Biomed. Informatics 60: 84-94 (2016)
[c14]
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Jane L. Shellum, Robert R. Freimuth, Steve G. Peters, Rick Nishimura, Rajeev Chaudhry, Steve Demuth, Amy Knopp, Tim Miksch, Dawn S. Milliner:
Knowledge as a Service at the Point of Care. AMIA 2016
[c13]
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James M. Hoffman, Henry M. Dunnenberger, Jonathan D. Burlison, Michelle Whirl Carrillo, Robert R. Freimuth, Marc S. Williams, Stuart A. Scott, Josh F. Peterson, Heidi L. Rehm, Teri E. Klein, Mary V. Relling, Kelly E. Caudle:
The Clinical Pharmacogenetics Implementation Consortium (CPIC) Term Standardization for Clinical Pharmacogenetic Test Results: Alleles and Phenotypes. CRI 2016
[c12]
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Hua Min, Stuart Turner, Sherri de Coronado, Brian Davis, Trish Whetzel, Robert R. Freimuth, Harold R. Solbrig, Richard C. Kiefer, Michael Riben, Grace A. Stafford, Lawrence W. Wright, Riki Ohira:
Towards a Standard Ontology Metadata Model. ICBO/BioCreative 2016
[c11]
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Jessica D. Tenenbaum, Subha Madhavan, Robert R. Freimuth, Joshua C. Denny, Lewis J. Frey:
Translational Bioinformatics 101. PSB 2016: 552-556
2015
[j8]
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Brian H. Shirts, Joseph S. Salama, Samuel J. Aronson, Wendy K. Chung, Stacy W. Gray, Lucia A. Hindorff, Gail P. Jarvik, Sharon E. Plon, Elena M. Stoffel, Peter Tarczy-Hornoch, Eliezer M. Van Allen, Karen E. Weck, Christopher G. Chute, Robert R. Freimuth, Robert Grundmeier, Andrea L. Hartzler, Rongling Li, Peggy L. Peissig, Josh F. Peterson, Luke V. Rasmussen, Justin B. Starren, Marc S. Williams, Casey Lynnette Overby:
CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record. J. Am. Medical Informatics Assoc. 22(6): 1231-1242 (2015)
[j7]
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Matthias Samwald, José Antonio Miñarro-Giménez, Richard D. Boyce, Robert R. Freimuth, Klaus-Peter Adlassnig, Michel Dumontier:
Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies. BMC Medical Informatics Decis. Mak. 15: 12 (2015)
[c10]
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Margaret K. Linan, Davide Sottara, Robert R. Freimuth:
Creating Shareable Clinical Decision Support Rules for a Pharmacogenomics Clinical Guideline Using Structured Knowledge Representation. AMIA 2015
[c9]
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Josh F. Peterson, Marc S. Williams, Casey L. Overby, Robert R. Freimuth, Iftikhar J. Kullo:
Public Implementation Resources for Genomic Medicine. AMIA 2015
2014
[c8]
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Robert R. Freimuth, Kelly Wix, Qian Zhu, Mark Siska, Christopher G. Chute:
Evaluation of RxNorm for Medication Clinical Decision Support. AMIA 2014
[c7]
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Casey L. Overby, Luke V. Rasmussen, Andrea L. Hartzler, John J. Connolly, Josh F. Peterson, RoseMary Hedberg, Robert R. Freimuth, Brian H. Shirts, Joshua C. Denny, Eric B. Larson, Christopher G. Chute, Gail P. Jarvik, James D. Ralston, Alan R. Shuldiner, Iftikhar J. Kullo, Peter Tarczy-Hornoch, Marc S. Williams:
A Template for Authoring and Adapting Genomic Medicine Content in the eMERGE Infobutton Project. AMIA 2014
2013
[j6]
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Cui Tao, Guoqian Jiang, Thomas A. Oniki, Robert R. Freimuth, Qian Zhu, Deepak K. Sharma, Jyotishman Pathak, Stanley M. Huff, Christopher G. Chute:
A semantic-web oriented representation of the clinical element model for secondary use of electronic health records data. J. Am. Medical Informatics Assoc. 20(3): 554-562 (2013)
[j5]
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Qian Zhu, Robert R. Freimuth, Zonghui Lian, Scott Bauer, Jyotishman Pathak, Cui Tao, Matthew J. Durski, Christopher G. Chute:
Harmonization and semantic annotation of data dictionaries from the Pharmacogenomics Research Network: A case study. J. Biomed. Informatics 46(2): 286-293 (2013)
[j4]
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Qian Zhu, Robert R. Freimuth, Jyotishman Pathak, Matthew J. Durski, Christopher G. Chute:
Disambiguation of PharmGKB drug-disease relations with NDF-RT and SPL. J. Biomed. Informatics 46(4): 690-696 (2013)
[j3]
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Stacey J. Winham, Robert R. Freimuth, Joanna M. Biernacka:
A weighted random forests approach to improve predictive performance. Stat. Anal. Data Min. 6(6): 496-505 (2013)
[c6]
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Qian Zhu, Jyotishman Pathak, Robert R. Freimuth, Christopher G. Chute:
Using standardized clinical data modeling and knowledge representation to compute pharmacogenomic data elements. AMIA 2013
[c5]
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Matthias Samwald, Robert R. Freimuth, Joanne S. Luciano, Simon M. Lin, Robert L. Powers, M. Scott Marshall, Klaus-Peter Adlassnig, Michel Dumontier, Richard D. Boyce:
An RDF/OWL Knowledge Base for Query Answering and Decision Support in Clinical Pharmacogenetics. MedInfo 2013: 539-542
2012
[j2]
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Stacey J. Winham, Colin L. Colby, Robert R. Freimuth, Xin Wang, Mariza de Andrade, Marianne Huebner, Joanna M. Biernacka:
SNP interaction detection with Random Forests in high-dimensional genetic data. BMC Bioinform. 13: 164 (2012)
[j1]
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Robert R. Freimuth, Elaine T. Freund, Lisa Schick, Mukesh K. Sharma, Grace A. Stafford, Baris E. Suzek, Joyce Hernandez, Jason Hipp, Jenny M. Kelley, Konrad Rokicki, Sue Pan, Andrew J. Buckler, Todd H. Stokes, Anna T. Fernandez, Ian Fore, Kenneth H. Buetow, Juli D. Klemm:
Life sciences domain analysis model. J. Am. Medical Informatics Assoc. 19(6): 1095-1102 (2012)
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Jyotishman Pathak, Richard C. Kiefer, Robert R. Freimuth, Suzette J. Bielinski, Christopher G. Chute:
Mining Genotype-Phenotype Associations from Electronic Health Records and Biorepositories using Semantic Web Technologies. AMIA 2012
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Cui Tao, Guoqian Jiang, Thomas A. Oniki, Robert R. Freimuth, Jyotishman Pathak, Qian Zhu, Deepak K. Sharma, Stanley M. Huff, Christopher G. Chute:
A Semantic-Web Oriented Representation of Clinical Element Model for Secondary Use of Electronic Healthcare Data. HISB 2012: 133
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Jyotishman Pathak, Laura C. Weiss, Matthew J. Durski, Qian Zhu, Robert R. Freimuth, Christopher G. Chute:
Integrating VA's NDF-RT Drug Terminology with PharmGKB: Preliminary Results. Pacific Symposium on Biocomputing 2012: 400-409

2000 – 2009

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2008
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Robert R. Freimuth, Michael W. Schauer, Preeti Lodha, Poornima Govindrao, Rakesh Nagarajan, Christopher G. Chute:
caBIG™ Compatibility Review System: Software to Support the Evaluation of Applications Using Defined Interoperability Criteria. AMIA 2008

Coauthor Index

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