Alzheimers Disease
Alzheimers Disease
Alzheimers Disease
Dr.Bushra rani
DPT-(SMC)
MS-RIU)
INTRODUCTION
Alzheimer's disease is a degenerative
brain disorder of unknown etiology which
is the most common form of dementia,
that usually starts in late middle age or in
old age, results in progressive memory
loss, impaired thinking, disorientation,
and changes in personality and mood.
There is degeneration of brain neurons
especially in the cerebral cortex and
presence of neurofibrillary tangles and
plaques containing beta-amyloid cells
ORIGIN OF
ALZHEIMER'S DISEASE
The disease was first described
by Dr. Alois Alzheimer, a German
physician, in 1906. Alzheimer had a
patient named Auguste D, in her
fifties who suffered from what
seemed to be a mental illness. But
when she died in 1906, an autopsy
revealed dense deposits, now called
neuritic plaques, outside and
around the nerve cells in her brain.
Inside the cells were twisted
strands of fiber, or neurofibrillary
tangles.
Since Dr. Alois Alzheimer's was the Auguste D
first person who discovered the
disease, AD was named after him.
Meaning
Alzheimer’s disease is a chronic, irreversible
a) Acetylcholine.
b) Somatostatin.
c) Substance P.
d) Norepinephrine
2.ENVIRONMENTAL FACTORS
• Cigarette smoking.
• Certain Infections.
1) Memory loss
2) Difficulty to performing familiar tasks
3) Problems with language
4) Disorientation to time and place
5) Poor or decreased judgment
6) Problems with abstract thinking
7) Misplacing things
8) Changes in mood or behavior
9) Changes in personality
10) Loss of initiative
SYMPTOM
• Confusion
S
• disturbances in short-term memory
• personality changes
• language difficulties