Cavum Oris's Tumor
Cavum Oris's Tumor
Cavum Oris's Tumor
LEUCOPLAKIA : - Hyperkeratosis
- Premaligna
MUCOCELE / KISTA RETENSI
RANULA : - Marsupialisation
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Cavum oris cancer:
Origin from epitel/come from mucosa or salivary gland in cavum
oris’s wall and organ in mouth, SCC 90%
Lip (13%)
Tongue 2/3 anterior (37%)
Mucosa bukal (10%)
Base mouth
Gingiva upper and lower
Palatum durum, Molle's Palatum
Base mouth (15%)
Retromolar's Trigonum (Cancer-UICC's Against's Union's
International's 2002
Cavum Oris border:
Anterior : Side vermilion upper lip and lower lip
Superior : Palatum durum and molle
Lateral : Right Bukal and left
Inferior : Base mouth and tongue
Posterior : Arkus faringeus anterior left right and
uvula, Arkus glossoplatinus right left, Side
lateral tongue base, Papilla sirkumvalata
tongue.
not include to oris cavity cancer:
Sarkoma and savage tumor odontogen in maksila or
mandibula
Soft network Sarkoma and nerve perifer in lip or
cheek
Lip skin Karsinoma or cheek skin
Epidemiology
Insidens and relative frequency
In indonesia 1, 5 - 5% from entire cancers.
Most often involve tongue (37%)
Man: Woman = 3/2 – 2/1
Age on 40 thn (70%)
Widespre at world, Insidens at french and indians,
Low at japanese
Etiology
Tobacco (cigarette smoke)
Alcohol
Tooth Karies
Mouth Higiene
Virus infection (HPV's, EBV, HIV)
Siflis, Syndrome's Vinson's Plummer
Imunodefisiency
Susur (tobacco)
Leukplakia/eritroplakia
HISTOPATOLOGI CLASSIFICATION
a. Histopatology types
NO TYPE of HISTOLOGY ICD.M
1 Squamous cell carc. 5070 / 3
2 Adenocarcinoma 8140 / 3
3 Adenoid cyst. carc 8200 / 3
4 Ameloblastic carc 9270 / 2
5 Adenolymphoma 8561 / 3
6 Mal. Mixed tumor 8940 / 3
7 Pleomorphic carc 8941 / 3
8 Melanoma maligna 8720 / 3
9 Lymphoma maligna 9590 / 3 - 9711/3
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b. Differensiation Degrees
DIFFERENSIA
TION
DEGREES
GRADE KETERANGAN
G1 Well Differensiation
G2 Moderate Differensiation
G3 Bad Differensiation
G4 Undifferensiated =
anaplastik
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Supporting investigation
History taking:
Long Ulcus
Pain time
Haemorrage
Smoke/alcohol story
Social-ekonomy
Physical Inspection / palpasi bimanual
Initially : White/red pockmarked
Leukoplakia/eritroplakia, Without ulcerasi
Advanced : Ulcus, Indurasi, Infiltratif, Fungating, Eksofitik
SUPPORTING INVESTIGATION
1. Radiography investigation
a. Artless X-foto
X-foto mandibula AP/lateral, Eisler, Panoramik, Oklusal
(Gingiva mandibula cling in mandibula Tumor)
Head X-foto lateral, Waters, Oklusal (Cling in maksila Tumor)
Hap's X-foto: Palatum durum
X-foto thorax: Metastase pulmonum
b. Imaging
USG hepar
CT scan / MRI: Lokoregional
Bone Scan
2. Laboratory investigation
DL, Etc for operation preparation
3. Pathology investigation
FNA (primary and metastase KGB)
Eksisi's biopsy: When does tumor <1cm (limit safety
margin 1cm from tumor side) general anesthesy
Incisional biopsy
Histopatology:
- type
- differentiation
- vast invasion of tumor
STAGING
T: Tx – Tis – T4 (0 – 2 – 4 cm)
N: Nx – N0 – N3 (0 – 2 – 4 – 6 cm)
M: Mx – M0 – M1
Staging of a disease 0 – IVc (every T, Every N, M1)
Therapy
Multidisiplin: Onkologi's operation, Neck head, Plastic,
Prostodonsi, Etc.
The aim of :
Primary tumor Eradikasi and metastase regional KGB
Returning function
Kosmetic