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Chapter 3: Lymphatic System

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The key takeaways are that the lymphatic system returns fluids leaked from blood vessels back to the bloodstream, transports fat from the intestines, and plays an important role in immunity by housing lymphocytes.

The main functions of the lymphatic system are to return excess interstitial fluid from tissues to veins, produce and house lymphocytes for the immune response, and transport absorbed fats from the intestines to blood.

The main components of lymph are water, proteins, blood cells, bacteria, viruses, cancer cells, and cell debris.

BIO310 / Lymphatic / NHM

LYMPHATIC SYSTEM
LESSON OUTCOMES
At the end of this chapter, you should be able to:

1) Define the functions of lymphatic system


2) Describe the formation of lymph
3) Compare blood, tissue fluid and lymph
4) Describe lymphatic vessels, ducts and lymphatic pathway
5) Describe the structures and functions of lymph nodes
6) Describe function of spleen, thymus, tonsils and Peyer’s
patches

BIO310 / Lymphatic / NHM


Functions of the Lymphatic System

 Lymphatic system: return fluids


that have leaked from the blood
vascular system back to the
blood.
 Consist of 3 parts:
a) Network of lymphatic vessels
b) Lymph: fluid contain in those
vessel
c) Lymph nodes: cleanse the
lymph as it passes through
them.
BIO310 / Lymphatic / NHM
Functions of the Lymphatic System

 Transports excess
interstitial fluid (lymph)
from tissues to the veins
 Produces and houses
lymphocytes for the
immune response
 Transports absorbed fats
from intestines to blood

BIO310 / Lymphatic / NHM


LYMPHATIC CHARACTERISTICS

Lymph (= clear water): excess


tissue fluid carried by lymphatic
vessels

Properties of lymphatic vessels


· One way system toward the heart
· No pump
· Lymph moves toward the heart
- Contraction of skeletal muscle
- Contraction of smooth muscle in vessels
BIO310 / Lymphatic / NHM
LYMPH
Materials returned to the blood
· Water
· Proteins
· Blood cells

Harmful materials that enter lymph vessels


· Bacteria
· Viruses
· Cancer cells
· Cell debris
BIO310 / Lymphatic / NHM
Vessels of the Lymphatic System
 Lymphatic capillaries:
 Smallest; found within most organs
 Interstitial fluids, proteins,
microorganisms, and fats can enter.

 Lymph ducts:
 formed from merging capillaries
 Similar in structure to veins
 Lymph is filtered through lymph
nodes
BIO310 / Lymphatic / NHM
BIO310 / Lymphatic / NHM
Lymph Capillaries:
· Walls overlap - flap-like minivalves
· Fluid leaks into lymph capillaries
· Capillaries anchored by filaments
· Higher press on inside closes minivalves
BIO310 / Lymphatic / NHM
Lymphatic Collecting Vessels

·Collects lymph from lymph


capillaries
·Carries lymph to and away
from lymph nodes
·Returns fluid to
circulatory veins near the
heart
-Right lymphatic duct
-Thoracic duct

BIO310 / Lymphatic / NHM


BIO310 / Lymphatic / NHM
Lymph Nodes
· Filter lymph before it is
returned to the blood
· Defense cells within lymph
nodes
· Macrophages – engulf and
destroy foreign substances
· Lymphocytes – provide immune
response to antigens

BIO310 / Lymphatic / NHM


Lymph Node Structure

· Most are kidney-shaped,


less than 1 inch long
· Cortex
• Outer part
• Contains follicles –
collections of
lymphocytes
· Medulla
• Inner part
• Contains phagocytic
macrophages

BIO310 / Lymphatic / NHM


Flow of Lymph Through Nodes

· Lymph enters the convex


side through afferent
lymphatic vessels
· Lymph flows through a
number of sinuses inside
the node
· Lymph exits through
efferent lymphatic vessels
· Fewer efferent than
afferent vessels causes flow
to be slowed
BIO310 / Lymphatic / NHM
BIO310 / Lymphatic / NHM

LYMPHOID ORGANS
Organs of the Lymphatic System

 Lymphoid organs and tissues


provide structural basis of the
immune system.
 Play roles in body’s defense
mechanisms.
 Include – Spleen, thymus,
tonsils:
 Sites for lymphocyte
production

BIO310 / Lymphatic / NHM


The Spleen

· Located on the left side of the


abdomen
· Site for lymphocyte proliferation
· Filters blood
· Destroys worn out blood cells
· Forms blood cells in the fetus
· Acts as a blood reservoir

BIO310 / Lymphatic / NHM


The Thymus

· Located low in the throat,


overlying the heart
· Functions at peak levels only
during childhood
· Produces hormones (thymosin)
to program lymphocytes
· Maturation site for T
lymphocyte

BIO310 / Lymphatic / NHM


Mucosa-Associated Lymphatic Tissue
(MALT)
• Acts as a sentinal to protect
respiratory and digestive
tracts.

• Includes:
·Tonsils
·Peyer’s patches
·Other small accumulations of
lymphoid tissue

BIO310 / Lymphatic / NHM


Tonsils

· Small masses of lymphoid


tissue around the entrance
of the pharynx (throat)
· Trap and remove bacteria
and other foreign materials
(food and inhaled air)
· Tonsillitis is caused by
congestion with bacteria

BIO310 / Lymphatic / NHM


Peyer’s Patches

· Found in the wall of the small intestine


· Resemble tonsils in structure
· Capture and destroy bacteria in the intestine

BIO310 / Lymphatic / NHM


THE END

BIO310 / Lymphatic / NHM

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