Anemia
Anemia
Anemia
• Neonatal period
• Enclosed hemorrhage: suggests obstetric trauma or severe
perinatal distress
• Caput succedaneum, cephalhematoma, intracranial hemorrhage,
visceral hemorrhage
• Defects in hemostasis
• Congenital coagulation factor deficiency
• Consumption coagulopathy: DIC, sepsis
• Vitamin K dependent factor deficiency
• Failure to give vit K causes bleeding at 3-4 days of age
• Thrombocytopenia: immune, or congenital with absent radii
• Iatrogenic blood loss due to blood draws
HEMOLYTIC ANEMIA
• Congenital
• Diamond-Blackfan syndrome, congenital leukemia, sideroblastic
anemia
• Acquired
• Infection: Rubella and syphilis are the most common
• Aplastic crisis, aplastic anemia
PRESENTATION OF HYPOPLASTIC
ANEMIA
• Uncommon
• Presents after 48 hours of age
• Absence of jaundice
• Reticulocytopenia
PRESENTATION OF OTHER FORMS
• Twin-twin transfusion
• Growth failure in the anemic twin, often > 20%
• Occult internal hemorrhage
• Intracranial: bulging anterior fontanelle and neurologic
signs (altered mental status, apnea, seizures)
• Visceral hemorrhage: most often liver is damaged and leads
to abdominal mass
• Pulmonary hemorrhage: radiographic opacification of a
hemithorax with bloody tracheal secretions
MANAGEMENT