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HEMEPARESIS

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CASE PRESENTATION

ON
hemiplegia

- BY
R.ROSHNI
16GTIT0016
PHARM D 4th YEAR
 A 65yrs adult male was admitted to the GM on 30.8.2017 in
GOVERNMENT HOSPITAL CHITTOOR bearing the IP no.
20191125117

 Chief complaints :

 C/O weakness of left upper and lower limb since yesterday


associated with deviation of angle of mouth.
Past history:
PTCA (Percutaneuos transluminal angioplasty) was done and the
necessary drugs was taken 2 years back.
no H/o of DM/HTN/TB/epilepsy
no H/o any previous surgery
no H/o of any blood transfusion/dry allergy
Family history:
Patient father has HTN
Personal history:
Alcoholic (-)
smoking(+)
Vitals and systemic examination

• Patient : C/C
• Afebrile
• BP : 160/100 mm of Hg
• PR: 88bpm
• CVS: S1,S2(+)
• RS: NVBS+
• CNS: conscious of angle of mouth to right
power: 3/5 in left upper limb
4/5 in left lower limb
LAB INVESTIGATIONS
 P/A: Soft
 Hemoglobin : 13 gm
 WBC count:11,180cells/cumm (4000-10,500)
 RBC :4.48mill/cumm
 MCH: 32.2pg(27-31)
 Lymphocyte: 48.7%(20-45)
 Monocyte : 1.4% (2-8)
 Hbs Ag : -ve
 HIV : Non reactive
PROVISIONAL DIAGNOSIS
Cerebro Vascular Artery left hemiparesis
secondary to right middle cerebral artery
infarct “ HEMEPARESIS”
Dosage regime
Drug name Dose Freq Day1 Day 2 Day 3 Day4 Day 5

T.Aspirin 75mg 0-1-0 + + + + +

T. 75 mg 0-1-0 + + + + +
Clopidrogel
T. 25 mg 1-0-0 + +
Metoprolol
T. Atorvae 20 mg 0-0-1 + + + + +

Inj. Pantop 40 mg IV 1-0-0 + + + + +

Inj. 20% IV 1-1-1 + + +


Mannitol
T. Lasix 40mg 1-0-0 + +

Inj. B12 1000mcg IM 0-1-0 + +

Inj. 5mg IV SOS +


Diazepam
PHYSIOTHERAPY
 ACTIVE MOVEMENTS AND STRENGTHENING
 FINGER GRIPPING AND STRENGTHENING AND GRASPING WAS TAUGHT
PATIENT COUNSELLING
1. Stay active to keep your muscle engaged.
2. Take low fat and salt and have diet rich in fruits, berries, nuts, vegetables
3. Stay hydrated.
4. Wear flat shoes for better balance’
5.Consider adding almond oil as it reduces cholesterol and improve blood flow
the brain.
6. Adding tulsi, garlic, ginger, turmeric will increase healing and strengthening
the muscles, circulatory system and immune system.
7. Take adequate rest for 7 to 8 hours sleep
8. Practice relaxation techniques
9. Choose eating white meat and avoid red meat.
10.Consuming carrot, beetroot, asparagus with your daily will supplement
your better health
DRUG INTERACTIONS
1. CLOPIDOGREL<>PANTOP: effectiveness of clopidogrel in preventing
heart attack or stroke is reduced.
2. ASPIRIN<>CLOPIDOGREL: adverse affects like unusual bleeding,
abdominal pain, weakness, appearance of black tarry stool’
3. ATORVOSTATIN<>CLOPIDOGREL: reduce the effect of clopidogrel.
Signs of blood clots such as chest pain, shortness of bteath, sudden
loss of vision or pain, redness or swelling in extremity.
4. ATORVOSTATIN<> PANTOP: increased blood levels and effects of
atorvastatin. Risk of liver damage, rhabdomyolysis, kidney damage.
5.ATORVASTATIN<> GRAPEFRUIT JUICE: side effects like liver damage
and rhabdomyolysis can be seen.
6.LASIX<>METOPROLOL: lower blood pressure and decreae in heart
rate is seen.
Pharmacist Intervention
 Given dual antiplatelet therapy could modified. According to NICE guidelines
recommend ASPIRIN OR CLOPIDOGREL. Recent research have proved that dual
therapy better curability but also have higher bleeding risk( recent research
in UK)
 Two Antihypertensive drugs have been included in the drug regimen which
was unneccesary. According to the NCBI, beta blocker +thiazides are enough
for the management of the hypertension in case of stroke and seizure.
 Baclofen could be added in the drug regimen for relaxation of of muscles.
 Along with the physiotherapy, MUSCLE CONSTRAINT INDUCED MOVEMENT
THERAPY could also be given for better therapeutic outcome.
PRESCRIPTION ANALYSIS
 According to current UK GUIDELINES and NICE GUIDELINES , dual anticoagulant
therapy is NOT recommended.
 The above prescription is found to be Irrational according to the NICE
GUIDELINES as it as unnecessary drugs in the drug regimen as it would
increase the ADRs and unwanted side effects.
 FOLLOW UP: ANTIHYPERTENSIVE DRUGS SHOULD BE STOPPED AS THE
BLOOD PRESSURE IS FOUND TO BE 160/90 mm of Hg WHICH DOES NOT
DUAL ANTIHYPERTENSIV THERAPY.
Thank you……

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