Animal Genetic Engineering 110816 (1) Unit 4
Animal Genetic Engineering 110816 (1) Unit 4
Animal Genetic Engineering 110816 (1) Unit 4
• See https://www.youtube.com/watch?v=ysq-lqp1-Ho
Establishing
transgenic
animals using
engineered
embryonic stem
(ES) cells
But what are ES
cells?
Transgenic animals-Engineered embyronic
stem cell method (used for gene knockouts)
Step 1: Get the ES cells
Step 2: Genetically engineer the ES cells
Step 3: Place
engineered ES cells
into an early embryo
(Fig. 19.4)
Nine-week-old "Little Nicky" peers out from August 07, 2008 | Bernann McKinney with one of
her carrying case in Texas. Little Nicky, the 5 puppies cloned from Booger, her late pet pit
a cloned cat, was sold to its new owner bull. It cost her $50,000. When Booger was
by Genetic Savings and Clone for $50,000 diagnosed with cancer, a grief-stricken McKinney
in December 2004. sought to have him cloned -- first by the now-
defunct Genetic Savings and Clone, and then by
South Korean company RNL Bio.