Congestive Heart Failure: Adopted From: Jarrod Eddy, PGY2 Internal Medicine Sub-I Lecture Series
Congestive Heart Failure: Adopted From: Jarrod Eddy, PGY2 Internal Medicine Sub-I Lecture Series
Congestive Heart Failure: Adopted From: Jarrod Eddy, PGY2 Internal Medicine Sub-I Lecture Series
ADOPTED FROM: Jarrod Eddy, PGY2 Internal Medicine Sub-I Lecture Series
Cardiac Physiology
(remember this?) CO = SV x HR HR: parasympathetic and sympathetic tone SV: preload, afterload, contractility
Preload
Def: Passive stretch of muscle prior to contraction Measurement: Swan-Ganz
LVEDP
Frank-Starling right?
Afterload
Def: Force opposing/stretching muscle after contraction begins Measurement: SVR Really a function of:
SVR Chamber radius (dilated cardiomyopathies) Wall thickness (hypertrophy)
Contractility
Def: Normal ability of the muscle to contract at a given force for a given stretch, independent of preload or afterload forces In other words:
How healthy is your heart muscle?
Physiologically
Systolic versus Diastolic
Functionally
How symptomatic is your patient?
Physical Exam
no distress at rest, except for feeling uncomfortable when lying flat for more than a few minutes Decreased pulse pressure cool peripheral extremities and cyanosis of the lips and nail beds Increased jugular venous pressure Rales Hepatomegaly Peripheral edema
Clinical Data
CXR
Kerleys lines : A and B Pulmonary Edema Cephalization Pleural Effusions (bilateral)
EKG
Left atrial enlargement Arrhythmias Hypertrophy (left or right)
Cardiomyopathy
Pulmonary Edema
Clinical Data
HEART SOUNDS!!! Systolic Murmurs
Mitral Regurg Aortic Stenosis
Diastolic Murmurs
Mitral Stenosis Aortic Insufficiency
Clinical Data
Laboratory Data Chemistry
Renal Function: Be Wary
BNP
Used in ER departments the world over Good negative correlation Need baseline for positivity Pulmonary versus cardiac dyspnea
Treatment of CHF
Treat Precipitating Factor(s)!!!! Adjust Heart Rate Decrease Preload Decrease Afterload Increase Contractility Increase Oxygenation
Treatment of CHF
Oxygen nasal, BiPAP, intubation Morphine Preload Reduction
Loop diuretics Nitrates ACEi / ARB Morphine
Treatment of CHF
Afterload Reduction
IV NTG, Nitroprusside Hydralazine ACEi / ARB
Ionotropic Support
Dopamine / Dobutamine Amrinone / Milrinone Digoxin (chronic) Mechanical (ABP)
Treatment of CHF
Beta-Blockers
Chronic > Acute Carvedilol (Coreg), Metoprolol (Toprol XL)
Fluid Balance
Restrict fluid / salt intake Monitor I/Os and daily weight Dialysis if needed
Aspirin
Precipitating Factors
Infection Pulm Embolus Noncompliance Arrhythmia Myocardial Infarction Stress reaction Sodium Intake Medications!!! Anemia Thyroid disorders Endocarditis
Admission Orders
Admit: Telemetry or ICU EKG STAT, then daily x 3 days 2D Echo CXR Labs: BMP, CBC, CE x 3, Coags, LFTs, UA Pulse ox (ABG) Oxygen ASA 325mg PO daily
Admission Orders
Nitroglycerin
Paste: 1 ACW TID Holding parameters IV: 50mg in 250cc D5W Titrate
Morphine 1-5mg IV q10-20 min prn Lasix 20-200mg IV (q 6-8 hours) ACEi
Captopril 6.25-50mg PO q8h Enalapril 2.5-20mg PO BID (0.625-2.5mg IV q6h)
Admission Orders
Beta Blocker
Probably not acutely Start Coreg or Toprol XL prior to discharge
Fluid Restrict 1000ml daily Low salt diet Daily patient weights Daily I/Os
Admission Orders
Dobutamine 500mg in 250cc D5W
3-10ug/kg/min
Digoxin
Probably not acutely Titrate to effective dose prior to discharge
IABP
Cardiogenic shock unresponsive to above tx
Dialysis
Critical renal failure patients