Formulation and Evaluation of Atenolol Floating Microspheres
Formulation and Evaluation of Atenolol Floating Microspheres
Formulation and Evaluation of Atenolol Floating Microspheres
Please cite this article in press as L. Satyanarayana and N. Sandeepthi, Formulation and Evaluation of
Atenolol Floating Microspheres, Indo Am. J. P. Sci, 2018; 05(01).
Design of Experiment
Table 1: Formulation of AtenololTartarate Floating Microsphere
Particle size
The particle size decreased from 223.2 to 97.1 μm 4%, decreases the particle size from 120.9 to 100.9
with increase in speed from 800 to 1400 rpm at 1 μm increase in the HPMC conc 2 to 4%, increases
% EC conc. And increases the particle size from the particle size from174.4 to 200.5 μm increases
130.5 to 240.6 μm with increases the EC conc 1 to the temperature 450 ,600.