Fundamentals of Pharmacology Australian 7th Edition Bullock Test Bank All Chapters
Fundamentals of Pharmacology Australian 7th Edition Bullock Test Bank All Chapters
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Exam
Name___________________________________
MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
1) When timing the dose for the fibrate gemfibrozil, the client should be advised to take it:
A) at bedtime.
B) upon arising in the morning.
C) with food.
D) half an hour before food.
Answer: D
Page Ref: 526
2) In considering therapy with HMG-CoA reductase inhibitors, it is important for the client to have regular:
A) liver function tests.
B) renal function tests.
C) blood clotting tests.
D) respiratory function tests.
Answer: A
Page Ref: 528
3) A hormone that affects blood pressure by facilitating an increased excretion of sodium and water is:
A) aldosterone.
B) ADH (vasopressin).
C) ANF.
D) oestrogen.
Answer: C
Page Ref: 537
4) Which one of the following chemical mediators can alter blood pressure via vasoconstriction?
A) Prostacyclin.
B) Endothelin-1.
C) Nitric oxide.
D) Prostaglandin E2.
Answer: B
Page Ref: 537
5) Which antihypertensive drug group should be avoided when a person has a pre-existing respiratory condition like
asthma?
A) Diuretics.
B) Calcium channel antagonists.
C) ACE inhibitors.
D) β-blockers.
Answer: D
Page Ref: 542
6) β-blockers should not be used in clients with the following conditions except:
A) complicated hypertension.
B) cardiac tamponade.
C) second-degree heart block.
D) sick sinus syndrome.
Answer: A
Page Ref: 542
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
7) If a second dose of diuretic is required, this is usually administered:
A) mid-morning.
B) midday or early afternoon
C) early evening.
D) at bedtime.
Answer: B
Page Ref: 545
8) Which of the following antihypertensive agents should be avoided in a client with constipation?
A) Calcium channel blockers.
B) Centrally-acting agents.
C) Angiotensin II antagonists.
D) ACE inhibitors.
Answer: A
Page Ref: 548
10) The form of angina pectoris that is associated with coronary vasospasm is called:
A) variant angina.
B) exertional angina.
C) classic angina.
D) stable angina.
Answer: A
Page Ref: 557
13) To avoid tolerance associated with continuous use of nitrate patches, the client should be advised to:
A) only apply the patches in the morning and evening.
B) only apply the patches when the angina symptoms become apparent.
C) have a 'nitrate-free' time from the patches for about 12 hours each day.
D) only apply the patches at bedtime.
Answer: C
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
Page Ref: 558
14) When using aspirin as an antiplatelet agent, how many days before any planned surgery or dental procedures
should be stopped?
A) 2 days.
B) 7 days.
C) 14 days.
D) 21 days.
Answer: B
Page Ref: 581
15) Which of the following diuretic agents is not recommended to be given with an ACE inhibitor?
A) Chlorothiazide.
B) Frusemide.
C) Ethacrynic acid.
D) Spironolactone.
Answer: D
Page Ref: 610, 612
16) Which one of the following is not a pathophysiological change associated with heart failure?
A) Increased myocardial oxygen demand.
B) Cardiac remodelling.
C) Decreased angiotensin II production.
D) Decreased myocardial contractility.
Answer: C
Page Ref: 609
17) The current optimal drug therapy in the management of heart failure is:
A) the cardiac glycoside, digoxin.
B) the dopamine agonist, dobutamine.
C) a non-selective β-blocker.
D) an ACE inhibitor and a diuretic.
Answer: D
Page Ref: 608
18) Which phase of the cardiac action potential is characterised by the opening of the sodium channel activation gate?
A) Phase 0.
B) Phase 1.
C) Phase 2.
D) Phase 3.
Answer: A
Page Ref: 628
19) Which one of the following mechanisms describes the general action of antidysrhythmic agents?
A) Impeding the movement of ions across cardiac cell membranes.
B) Enhancing cardiac automaticity.
C) Shortening the cardiac action potential.
D) Enhancing impulse conduction in the heart.
Answer: A
Page Ref: 629
20) Clients who have renal impairment are at risk of developing ________ during treatment with ACE inhibitors.
A) hypokalaemia
B) hyperkalaemia
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
C) hyponatraemia
D) hypernatraemia
Answer: B
Page Ref: 610
23) An important consideration associated with anaemias caused by vitamin B 12 deficiency is that:
A) high doses of vitamin B12 can induce hyperkalaemia.
B) in pernicious anaemia, vitamin B12 must be administered parenterally.
C) the clinical form of vitamin B12 is called pyridoxine.
D) solutions of vitamin B12 must be kept refrigerated.
Answer: B
Page Ref: 653
25) To reduce the gastric irritation associated with oral iron therapy, the person should be advised to:
A) take the preparation as a suppository.
B) take the preparation with or immediately after meals.
C) take the preparation at bedtime.
D) take the preparation with an antacid.
Answer: B
Page Ref: 653
26) Which one of the following respiratory illnesses affects approximately 10% of adult Australians?
A) Bronchial asthma.
B) Chronic bronchitis.
C) Emphysema.
D) Cystic Fibrosis
Answer: A
Page Ref: 660
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
27) The extrinsic form of asthma is characterised by:
A) an autonomic nervous system imbalance.
B) a tendency to develop in older individuals.
C) the release of chemical mediators from immune cells in lung tissue.
D) the dominance of the parasympathetic stimulation of the airways.
Answer: C
Page Ref: 660
28) Which one of the following antiasthma agents acts directly on intracellular cAMP levels?
A) Muscarinic antagonists.
B) Methylxanthines.
C) β agonists.
D) Leukotriene receptor antagonists.
Answer: B
Page Ref: 662
29) Which one of the following statements about oxygen therapy is true?
A) Prolonged therapy with 100% oxygen can lead to toxicity regardless of underlying pathology.
B) Standard oxygen therapy for clients with long-term chronic obstructive airways disease will lead to
hyperventilation.
C) Hyperbaric oxygen therapy is useful in the care of premature infants.
D) Peak flow readings determine the level of oxygen therapy required.
Answer: A
Page Ref: 673
30) Inhaled corticosteroids should be considered as part of the medication regime for asthma if the person is using
their β2 agonists more than:
A) one time each month.
B) three times each month.
C) three to four times each week.
D) two times each month.
Answer: C
Page Ref: 668
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
C) LDL.
D) IDL.
Answer: B
Page Ref: 523
34) The inclusion of ________ in the diet may help to avoid hypercholesterolaemia.
A) chicken
B) sardines
C) mutton
D) beef
Answer: B
Page Ref: 525
35) An unwelcome but possibly benign effect of nicotinic acid treatment is:
A) petechial rash.
B) constipation.
C) loose stools.
D) skin flushes and itching.
Answer: D
Page Ref: 526
37) The benefit of ________ for the treatment of thrombosis is that it is clot specific thereby reducing the risk of
generalised haemorrhage.
A) warfarin
B) urokinase
C) streptokinase
D) tissue plasminogen activator
Answer: D
Page Ref: 585
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
40) The hypokalaemia that may be induced by a loop diuretic can be lessened or prevented by concurrent use of:
A) potassium chloride.
B) an angiotensin II receptor antagonist.
C) an ACE inhibitor.
D) all of the above.
Answer: D
Page Ref: 598
41) Clients on atorvastatin should avoid ________ during therapy because it may increase the amount of atorvastatin
in their circulation and therefore increase the chances of adverse effects occurring.
A) alcohol
B) milk
C) grapefruit juice
D) leafy green vegetables
Answer: C
Page Ref: 528
42) Which of the following nitrate formulations is not used to prevent angina symptoms?
A) Oral isosorbide dinitrate controlled-release tablets.
B) Oral isosorbide mononitrate controlled-release tablets.
C) Transdermal glyceryl trinitrate.
D) Sublingual isosorbide dinitrate.
Answer: D
Page Ref: 558
43) After about ________ of oral anticoagulant therapy with warfarin, the heparin can be withdrawn as it takes this
amount of time for the oral anticoagulant to exert its effect.
A) two hours
B) twelve hours
C) 24 hours
D) 48 hours
Answer: D
Page Ref: 575
46) Treatment with iron supplementation is usually continued for about ________ to ensure replenishment of iron
stores in iron deficiency anaemia.
A) two weeks
B) one month
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
C) two months
D) three months
Answer: D
Page Ref: 653
47) Which of the following actions will not reduce the effectiveness of acetylcysteine nebuliser solution used for the
treatment of cystic fibrosis?
A) Making contact between the acetylcysteine nebuliser solution and rubber.
B) Making contact between the acetylcysteine nebuliser solution and iron.
C) Making contact between the acetylcysteine nebuliser solution and copper.
D) Diluting the acetylcysteine nebuliser solution with equal volumes of sodium chloride 0.9%.
Answer: D
Page Ref: 683
48) The mechanism of action of the antihyperlipidaemic agents called the statins involves:
A) inhibition of the rate-limiting enzyme in hepatic cholesterol synthesis.
B) binding to bile salts removing them from the body.
C) an interaction with peroxisome proliferator-activated receptor alpha.
D) inhibiting the absorption of dietary cholesterol from the gastrointestinal tract.
Answer: A
Page Ref: 527
49) Which one of the following antihypertensive drug groups is thought to reduce sympathetic drive in the
myocardium and mediate the release of renin?
A) β-blockers.
B) Calcium channel antagonists.
C) Angiotensin II receptor antagonists.
D) Thiazides.
Answer: A
Page Ref: 542
50) Which one of the following is an endogenous substance known to inhibit coagulation?
A) cAMP.
B) Thromboxane A2.
C) ADP.
D) von Willebrand factor.
Answer: A
Page Ref: 575
52) To avoid ototoxicity, intravenous (IV) frusemide must be injected no faster than 4 mg/min. If the dose ordered is
20 mg IV how quickly can it be administered?
A) Over at least 5 minutes.
B) Over at least 4 minutes.
C) Over at least 12 seconds.
D) Over at least 10 minutes
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
Answer: A
Page Ref: 597
53) The main site of action of the potassium-sparing diuretic spironolactone is the:
A) proximal convoluted tubule.
B) ascending limb of Henle.
C) distal convoluted tubule.
D) glomerulus.
Answer: C
Page Ref: 596
55) Infusing a hypotonic solution will have which of the following cellular effects?
A) There will be no net shift of fluid.
B) Fluid will shift from the intracellular space to dilute the extracellular space causing cell shrinkage.
C) Sodium will move from the extracellular space into the intracellular space.
D) Fluid will shift from the extracellular space to a more concentrated intracellular space causing cell swelling.
Answer: D
Page Ref: 640
56) Premature babies receiving long-term oxygen therapy are at risk of:
A) otitis media.
B) ototoxicity.
C) retinal damage.
D) macular degeneration.
Answer: C
Page Ref: 673
57) Which of the following chemical mediators can alter blood pressure via vasodilation?
A) Nitric oxide
B) Endothelin-1
C) ANF
D) Vasopressin
Answer: A
Page ref: 537
58) Which of the following antihypertensive agents should be avoided in a person with depression?
A) Calcium channel blockers.
B) Centrally acting agents.
C) Angiotensin II antagonists.
D) ACE inhibitors.
Answer: B
Page Ref: 548
59) Long term statin therapy has been linked to an increased incidence of
A) stroke.
B) heart disease.
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
C) cataract development.
D) Alzheimer's disease.
Answer: C
Page ref: 528
62) Adverse effects such as an unproductive cough and taste disturbances may occur from which category of
medicine frequently used for treatment of heart failure?
A) Diuretics.
B) Aldosterone antagonists.
C) Cardiac glycosides.
D) ACE inhibitors.
Answer: D
Page ref: 610
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
66) High doses of vitamin B12 may cause
A) hypotension.
B) hypokalaemia.
C) constipation.
D) folate deficiency.
Answer: B
Page ref: 653
2. Explain why acidification of urine might be undertaken in individuals with urinary tract infections or urinary
catheters.
Answer: Bacteria are less likely to colonise the urinary tract in an acidic environment.
Page ref: 601
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
1) D
2) A
3) C
4) B
5) D
6) A
7) B
8) A
9) A
10) A
11) B
12) C
13) C
14) B
15) D
16) C
17) D
18) A
19) A
20) B
21) C
22) C
23) B
24) A
25) B
26) A
27) C
28) B
29) A
30) C
31) B
32) D
33) B
34) B
35) D
36) D
37) D
38) B
39) A
40) D
41) C
42) D
43) D
44) A
45) A
46) D
47) D
48) A
49) A
50) A
51) C
52) A
53) C
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
54) D
55) D
56) C
57) A
58) B
59) C
60) D
61) A
62) D
63) B
64) A
65) C
66) B
Copyright ©2014 Pearson Australia (a division of Pearson Australia Group Pty Ltd) –9781442563100/Bullock/Fundamentals of Pharmacology/7e
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The Project Gutenberg eBook of
Andersonville diary
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Language: English
ESCAPE,
——AND——
JOHN L. RANSOM,
LATE FIRST SERGEANT NINTH MICH. CAV.,
AUTHOR AND PUBLISHER.
AUBURN, N. Y.
1881.
“Entered according to act of Congress, in the year 1881, by
John L. Ransom, in the office of the Librarian of
Congress, at Washington.”
D E D I C AT I O N .
TO THE
—IN—
ANDERSONVILLE,
BY THE AUTHOR.
John L. Ransom.
(From a photograph taken two months
before capture.)
INTRODUCTION.
THE CAPTURE 9
NEW YEAR’S DAY 23
PEMERTON BUILDING 34
ANDERSONVILLE 41
FROM BAD TO WORSE 65
THE RAIDERS PUT DOWN 75
AN ACCOUNT OF THE
81
HANGING
MOVED JUST IN TIME 91
HOSPITAL LIFE 97
REMOVED TO MILLEN 109
ESCAPE BUT NOT ESCAPE 120
RE-CAPTURED 127
A SUCCESSFUL ESCAPE 136
SAFE AND SOUND 154
THE FINIS 160
MICHAEL HOARE’S ESCAPE 167
REBEL TESTIMONY 172
SUMMARY 187
THE WAR’S DEAD 188
EX-PRISONERS AND
189
PENSIONERS
LIST OF THE DEAD 193
A LIST OF OFFICERS
IMPRISONED AT CAMP 289
ASYLUM
THE CAPTURE.