Micromachines 14 01281
Micromachines 14 01281
Micromachines 14 01281
Article
Performance Analysis of an Aperture-Coupled THz Antenna for
Diagnosing Breast Cancer
Anupma Gupta 1 , Vipan Kumar 2 , Dinesh Garg 3 , Mohammed H. Alsharif 4, * and Abu Jahid 5, *
Abstract: The most important technique for exposing early-stage breast cancer is terahertz imaging.
It aids in lowering the number of breast cancer-related fatalities and enhancing the quality of life.
An essential component of developing the THz imaging system for high-quality photos is choosing
the right sensor. In this article, a wideband antenna for microwave imaging of breast tissue with an
operating frequency of 30 GHz (107 GHz to 137 GHz) is constructed and analyzed. An aperture-
coupled antenna with an optimized ground aperture is proposed and analyzed, which made it
possible to obtain better and consistent impedance matching in the wideband spectrum. The variation
of backscattered signal energy in body tissue is assessed with healthy breast tissue and in the presence
of malignant cells. A significant difference in energy scattering is observed for both situations. The
suggested antenna’s linear and stable time domain characteristics make it an appropriate component
for THz imaging technology.
Citation: Gupta, A.; Kumar, V.; Garg, Keywords: aperture-coupled; breast cancer; THz imaging technology; polyamide
D.; Alsharif, M.H.; Jahid, A.
Performance Analysis of an
Aperture-Coupled THz Antenna for
Diagnosing Breast Cancer. 1. Introduction
Micromachines 2023, 14, 1281.
1.1. Background and Motivation
https://doi.org/10.3390/mi14071281
Terahertz imaging is growing rapidly as a noninvasive technology for the detection
Academic Editor: Antonella Battisti of unhealthy and cancerous cells in breast tissue. THz imaging is a non-ionizing and
Received: 19 April 2023
low-power technology, making it biologically hazardous and free for in vitro and in vivo
Revised: 11 June 2023
operations. One THz frequency requires an energy level of about 4.14 meV, whereas the
Accepted: 20 June 2023 minimum X-ray energy level is 0.12 Kev. Therefore, THz imaging is safe and reduces the
Published: 22 June 2023 ionization effects as compared to conventional methodologies. This non-ionizing behavior
is an important and critical feature that advances THz systems in healthcare applications [1].
High-frequency THz electromagnetic radiation has a fundamental time period of about
1-ps, which makes the biological investigation system faster and limits the thermal effects
Copyright: © 2023 by the authors. on healthy tissue. Due to shorter wavelengths, THz frequencies have a superior imaging
Licensee MDPI, Basel, Switzerland. resolution and have enhanced transmission properties in thick and fatty tissues. The
This article is an open access article electromagnetic spectrum for the terahertz frequency range is generally expected from
distributed under the terms and 0.1 THz (100 GHz) up to 10 THz [2].
conditions of the Creative Commons
In THz imaging systems, variations in water contents of healthy and unhealthy cells
Attribution (CC BY) license (https://
are analyzed to diagnose the existence of specific cancer cells and to measure the depth,
creativecommons.org/licenses/by/
location, and severity of damaged tissues. Unhealthy tumors and cancer cells have high
4.0/).
water levels, and THz photons are highly sensitive to water absorption. It helps in the
characterization of THz radiation in biological and medical imaging [3]. Pulsed THz
radiation can sense very small cancer cells and has the potential to differentiate between
healthy and cancer cells. THz imaging is useful for quick imaging during surgery, with clear
differentiation between peritumoral and cancerous cells, and provides accurate boundary
margins (thickness between cancer and normal cells) to the surgeon to aid in the removal
of unhealthy cells [4]. The THz radiation source is the most significant part of the THz
biomedical imaging system [5,6].
Table 1. Summary of the design methodology of investigated antennas for THz imaging.
Performance
Refs. Type Technique Limitation
Enhancement Factor
Dipole with GaAs Wide spectrum (120 GHZ)
[7] Not analyzed for application
substrate and higher directivity
Photo Conductive
Antenna Bow-Tie structure with
(PCA) plasmonic gratings by
[8] Reduce leakage current Not analyzed for application
etching widows in
substrate
improved gain and beam performance not evaluated for
[9] array with inset feed
width time domain response
Microstrip Patch Graphene and characterized for on-chip application based performance not
[10]
antenna reconfigurable patch application evaluated
Not evaluated for practical
Array of slotted patch
[16] higher gain application and omnidirectional
radiator
radiation pattern
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Table 1. Cont.
Performance
Refs. Type Technique Limitation
Enhancement Factor
analyzed for breast cancer
Metamaterial with
[11] miniaturization detection, only for front-to-front
defected ground
configuration
Miniaturization and
Metamaterial time domain analysis not
[12] CSIR loaded structure increasing the resonance
performed and narrow bandwidth
frequency
Improved reflection
[13] Slotted patch with PBG Sensitivity very low for cancer cell
properties
Size reduction and application based performance not
[17] Yagi-Uda PBG gratings
bandwidth enhancement evaluated
Reducing Q-factor to
[20] Circular radiator 4-graphene arc loaded Low gain
enhance bandwidth
[22] SIW Graphene and PBG Wider bandwidth Sensitivity very low for cancer cell
1.3. Contributions
The present study introduces and investigates an aperture-coupled THz antenna
with a polyamide substrate for the purpose of breast cancer detection in medical imaging.
Drawing from the relevant literature, THz imaging is based on the principle that changing
the electrical properties of bodily tissue leads to alterations in the backscattered parameters.
Cancerous tissue, possessing a higher dielectric constant than normal breast tissue due
to its high water content, is the focus of an investigation, with the deviation of the S11
signal being analyzed. The antenna developed in this study contributes to the field in the
following ways:
(1) It features a planar and straightforward structure that can be easily traced onto non-
planar breast tissue.
(2) Its wider impedance bandwidth allows for radiation penetration into tissue at different
depths.
(3) It offers higher gain.
(4) It displays good sensitivity to unhealthy tissue.
maximum impedance matching and −10 dB bandwidth. The |S11| parameter for the
proposed antenna with a rectangular aperture is represented in Figure 2. The antenna
shows a −10 dB impedance bandwidth from 0.107 THz to 0.137 THz. A wide bandwidth
of 30 GHz is suitable to achieve good resolution for breast cancer imaging. The VSWR plot
in Figure 3 represents the impedance matching of the antenna over the operating frequency
band. A VSWR value less than two is desired for the impedance matching.
Figure 1. Topology of the different parts of the proposed aperture-coupled structure: (a) uppersub-
strate printed with a radiator, (b) bottom substrate with a feedline, (c) ground plane with the aperture
below the bottom substrate, and (d) perspective view.
The size and position of the aperture are the most important design parameters of
aperture-coupled structures. Coupled power varies the resonance current and resistivity of
the patch and stimulates the multiple resonance mode, which helps to attain the broader
bandwidth. The position of the aperture is centered below the patch, as it provides the
dominant magnetic polarization and maximum coupling effect. Hence, it is required to
adjust the size of the aperture. The size of the coupling aperture should be smaller than
the radiator to agree with the maximum impedance matching, lower back scattered power,
and enhanced efficiency [21]. As the area of the aperture slot is increased, the coupling
effect is enhanced, but it leads to an increase of the antenna impedance. In turn, it causes
the deterioration of impedance matching [22]. Thus, to gain the optimum impedance
matching and broader bandwidth, the width (‘wc’) of the aperture slot is varied and
analyzed through a parametric sweep. The plot for varying the width reflection coefficient
is shown in Figure 4. The slot width is varied from 0.7 mm to 1.0 mm. Optimum coupling
is achieved at the width ‘wc’ of 0.9 mm. The bandwidth for the lower cut-off frequency
increases with the increasing slot width but reduces the impedance matching.
Figure 4. The |S11| parameter for the varying slot widths (wc).
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The radiation efficiency of the antenna over the entire frequency spectrum is plotted
in Figure 5. The antenna shows more than a 75% radiation efficiency. A 3D power pattern
is represented in Figure 6. It can be observed that gains of 6.38 dBi at 115 GHz, 4.96 dBi
at 125 GHz, and 6.34 dBi at 135 GHz are obtained. The maximum power is oriented
towards the front lobes, representing the low power loss in the back and side lobes. The
wide bandwidth and efficient radiation characteristics of the proposed antenna make it an
appropriate candidate for THz imaging.
Figure 6. The gain of the antenna (a) at 115 GHz (b), 125 GHz (c), and 135 GHz.
Figure 7. (a) Breast tissue with a tumor. (b) Simulation setup for cancer detection: a side-by-side
view and (c) a face-to-face view.
Table 3. Comparison of |S11| variations in the absence and presence of tumor w.r.t. (Figure 8).
Difference in Difference in
|S11| on Breast |S11| on Breast
Frequency at |S11| on Breast Magnitude of Magnitude of
with Tumor (dB) with Tumor (dB)
which |S11| is Tissue without |S11| with and |S11| with and
in Face-to-Face in Side-by-Side
Analyzed (GHz) Tumor (dB) without Tumor without Tumor
Configurations Configurations
(Face-to-Face) (Side-by-Side)
119 −26.5 −20 −22 6.5 dB 4.5 dB
130 −18 −21.5 −21.5 3.5 dB 3.5 dB
As studied in the literature [28–30], breast tissue includes different dielectric layers
with varying thickness. Variations in the dielectric materials have a significant impact on the
antenna performance and sensitivity to tumors. Thus, an analysis of the backscattered signal
for varying breast sizes of the radius R with a tumor and without a tumor is performed.
Figure 7a depicts a phantom model with a fat layer. In the case of a 70 mm spherical
phantom, the skin layer has a thickness of 3 mm, the fat layer has a thickness of 62 mm,
and a 5 mm tumor is present. For the 50 mm phantom, the skin layer thickness is 2.8 mm,
the fat layer radius is 42.2 mm, and the tumor measures 5 mm. In the case of a 30 mm
phantom, the skin thickness is 2.5 mm, the tumor radius is 4 mm, and the fat layer has a
radius of 23.5 mm. The reflection coefficient for varying the phantom sizes is shown in
Figure 9. It is evident that, as the phantom size increases, the backscattered signal shifts
upwards to 125 GHz and downwards towards higher frequencies. With a tissue size of
70 mm, the antenna covers the entire bandwidth spectrum from 112 GHz to 135 GHz,
exhibiting significant deviations in the reflection coefficient in the presence of unhealthy
tumor cells within the breast. For a radius of 70 mm, a maximum deviation of 7 dB is
observed at 127 GHz, while, for a radius of 30 mm, a maximum deviation of 4 dB occurs
at 117 GHz. These findings underscore the impact of breast size and tumor presence on
the backscattered signal. The results demonstrate the ability of the antenna to detect and
differentiate tumor-related deviations in the reflection coefficient within specific frequency
ranges. Such insights contribute to the understanding and development of efficient antenna
systems for terahertz imaging in breast cancer detection.
Figure 9. Backscattered signal for varying phantom sizes with the radius (R).
Figure 10 shows the transmission coefficient |S21| of the antenna for the two matching
antennas in a side-by-side and face-to-face configuration for different phantom sides. |S21|
Micromachines 2023, 14, 1281 9 of 15
is examined to take the far-field effect of the two antennas on each other over the whole
bandwidth. It should be low, as it indicates a direct power transfer from one antenna to
another. The |S21| value is below −30 dB for all the phantom sizes in both the side-by-side
and face-to-face configurations. Except at 137 GHz in the face-by-face configuration, a stable
|S21| is accomplished in both operational scenarios. The transmission coefficient exhibits
a similar type of volatility as shown in [21]. The electric field distribution is measured and
depicted in Figure 11 to support the fluctuation of the power distribution in heterogeneous
body tissues. It is obvious that the power absorbed by the tissue layers is not uniform,
and some of the absorbed power is taken up by the tumor, which causes deflections in the
radiation patterns coming from various ray directions.
Figure 11. Electric field distribution for a face-to-face (a–c) and side-by-side (d–f) configuration.
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Figure 12. (a) Transmitted and (b) received pulses for the face-to-face setup.
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Figure 13. (a) Transmitted and (b) received pulses for the side-by-side setup.
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Table 4. Comparison of the proposed THz imaging antenna with existing structures.
4. Conclusions
The configuration employed for the aperture-coupled patch antenna follows a stan-
dard design, which is specifically chosen to achieve two main objectives: a broad −10
dB impedance bandwidth and consistent operating characteristics across a wide range
of frequencies known as ultra-wideband (UWB) frequencies. This is accomplished by
utilizing a rectangular patch as the main element of the antenna, along with an optimized
coupling slot that facilitates the desired performance. To assess the antenna’s effectiveness
in the terahertz (THz) range, an equivalent tissue phantom is used as the testing medium.
The tissue phantom serves as a representative model for the evaluation of the antenna’s
performance. When the antenna is positioned on heterogeneous tissue, it exhibits a notable
ability to differentiate the backscattered signal. This means that the antenna is capable of
distinguishing between different signals reflected by various types of tissues. It is worth
noting that the electrical characteristics of the tissue tend to change with the variations in
the magnitude of the backscattered signal. This property can be effectively utilized to obtain
imaging information. By analyzing the variations in the |S11| parameter, which quantifies
the reflection coefficient of the antenna, significant differences can be observed. Specifically,
in a face-to-face scenario at 125 GHz, there is a maximum deviation of 5 dB, while, in a side-
by-side scenario at the same frequency, the maximum deviation is 7 dB. These deviations
indicate the potential for acquiring valuable information through the backscattered signal.
Moreover, the distribution of the electric field generated by the antenna is assessed to
evaluate the presence of a nonuniform power distribution. This analysis helps to determine
if there are any areas where the power concentration is significantly imbalanced, which
could affect the antenna’s overall performance. Additionally, the linearity of the timing
signals is evaluated using the received and transmitted pulses. By examining the timing
characteristics of these pulses, it is possible to determine whether the antenna operates
linearly and accurately in terms of timing. This assessment is crucial to ensure reliable and
precise signal transmission and reception. In summary, the configuration of the aperture-
coupled patch antenna is carefully designed to achieve a broad impedance bandwidth
and stable performance at UWB frequencies. By utilizing an equivalent tissue phantom,
the antenna’s performance in the THz range was evaluated, particularly in terms of its
ability to differentiate backscattered signals. The variations in the electrical characteristics
of the tissue, caused by changes in the backscattered signal magnitude, can be exploited
for imaging purposes. The analysis of the |S11| parameter reveals significant deviations,
allowing for valuable information extraction. The distribution of the electric field and the
linearity of timing signals were also examined to assess the power distribution and signal
timing accuracy, respectively.
Author Contributions: Conceptualization, A.G. and V.K.; methodology, A.G. and D.G.; software,
A.G.; validation, M.H.A. and A.J.; investigation, D.G. and M.H.A.; resources, A.G.; data curation,
A.G.; writing—original draft preparation, A.G. and V.K.; writing—review and editing, M.H.A., A.J.
and D.G.; and visualization, A.G. and V.K. All authors have read and agreed to the published version
of the manuscript.
Funding: This research received no external funding.
Data Availability Statement: Not applicable.
Conflicts of Interest: The authors declare no conflict of interest.
Micromachines 2023, 14, 1281 14 of 15
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