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Warnings Regarding The Potential Coronavirus Disease 2019 Covid 19 Transmission Risk Vaccination Is Not Enough

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Infection Control & Hospital Epidemiology (2021), 1

doi:10.1017/ice.2021.63

Letter to the Editor

Warnings regarding the potential coronavirus disease 2019


(COVID-19) transmission risk: Vaccination is not enough
Tianming Zhao MD candidate1,a , Chengyang Hu MD1,2,a, Mubashir Ayaz Ahmed MD3 , Ce Cheng DO4 , Yue Chen5
and Chenyu Sun MD, MSc3
1
Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China, 2Department of Humanistic Medicine,
School of Humanistic Medicine, Anhui Medical University, Hefei, Anhui, China, 3Internal Medicine, AMITA Health Saint Joseph Hospital Chicago, Chicago, Illinois,
United States, 4The University of Arizona College of Medicine at South Campus, Tucson, Arizona, United States and 5Department of Clinical Medicine, School of
the First Clinical Medicine, Anhui Medical University, Hefei, Anhui, China

To the Editor—Caused by the severe acute respiratory syndrome may still be susceptible during the first few days to weeks after vac-
coronavirus-2 (SARS-CoV-2), the coronavirus disease 2019 cination, whereas the general public may not fully understand this
(COVID-19) pandemic has continued to spread around the world, and may be less compliant with current nonpharmaceutical inter-
resulting in a global health emergency of inconceivable ventions (NPIs) immediately after receiving the vaccine.
magnitude.1,2 Currently, several vaccines, including the Pfizer- In conclusion, uncertainties remain in the long-term effect of
BioNTech COVID-19 vaccine and the Moderna COVID-19 vac- SARS-CoV-2 vaccines, and accessibility of vaccines is still limited.
cine, have been authorized for emergency use to prevent Strict public health policies aiming to reduce the spread of SARS-
COVID-19.3 A previous study indicated that the use of a vaccine CoV-2 are still warranted and should not be ignored.
in combination with measures that reduce contact between suscep-
tible individuals and COVID-19 carriers will significantly decrease Financial support. No financial support was provided relevant to this article.
the per-day risk of infection as long as at least 50% of people receive Conflicts of interest. All authors report no conflicts of interest relevant to this
it.4 In this article, these researchers also expressed their concern article.
that potential vaccine defiance and abandoning other protection
options may cause even worse results in COVID-19 prevention.4
References
In addition, due to the limited supply of COVID-19 vaccine in
the United States, Centers for Disease Control and Prevention 1. Twomey JD, Luo S, Dean AQ, et al. COVID-19 update: the race to therapeu-
(CDC) recommends that initial supplies of SARS-CoV-2 vaccine tic development. Drug Resist Updat 2020;53:100733.
be allocated to healthcare personnel and long-term care facility res- 2. Artese A, Svicher V, Costa G, et al. Current status of antivirals and druggable
targets of SARS CoV-2 and other human pathogenic coronaviruses. Drug
idents.5 Considering the accessibility of vaccines in different
Resist Updat 2020;53:100721.
regions and populations around the world, public health polices
3. Different COVID-19 vaccines. Centers for Disease Control and Prevention
including keeping social distance and wearing face masks, are still website. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-
of great importance, even though an effective vaccine has been vaccines.html. Published 2020. Accessed February 8, 2021.
introduced. 4. Abo SMC, Smith SR. Is a COVID-19 vaccine likely to make things worse?
Furthermore, according to Morbidity and Mortality Weekly Vaccines (Basel) 2020;8(4):E761.
Report from the CDC,6 several issues still need to be explored: 5. When vaccine is limited, who gets vaccinated first? Centers for Disease
(1) No data assessing the efficacy of vaccine in prevention of Control and Prevention website. https://www.cdc.gov/coronavirus/2019-
asymptomatic SARS-CoV-2 infection are available; thus, the ncov/vaccines/recommendations.html. Published 2020. Accessed February
potential transmission risk of SARS-CoV-2 among asymptomatic 8, 2021.
6. Oliver SE, Gargano JW, Marin M, et al. The Advisory Committee on
infected individuals cannot be ignored, even after vaccination. (2)
Immunization Practices interim recommendation for use of Pfizer-
Considering the time interval between the invention of the Pfizer-
BioNTech COVID-19 vaccine—United States, December 2020. Morb
BioNTech SARS-CoV-2 vaccine and its emergency use authoriza- Mortal Wkly Rep 2020;69:1922–1924.
tion (EUA), the long-term effects of this vaccine (including adverse 7. The Vaccines and Related Biological Products Advisory Committee meeting,
and protected effects) are still not entirely clear, and further sur- December 10, 2020. FDA Briefing Document, Pfizer-BioNTech COVID-19
veillance is still necessary. (3) It takes ~14 days to obtain protection vaccine. US Food and Drug Administration website. https://www.fda.gov/
from infection after the first shot of Pfizer vaccine,7 and individuals media/144245/download. Published 2020. Accessed February 8, 2021.

Author for correspondence: Chenyu Sun, E-mail: drsunchenyu@yeah.net


a
Authors of equal contribution.
Cite this article: Zhao T, et al. (2021). Warnings regarding the potential coronavirus
disease 2019 (COVID-19) transmission risk: Vaccination is not enough. Infection Control
& Hospital Epidemiology, https://doi.org/10.1017/ice.2021.63

© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America.

Downloaded from https://www.cambridge.org/core. 10 Mar 2021 at 00:55:07, subject to the Cambridge Core terms of use.

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