Micromass GCT Classic Site Preparation Guide
Micromass GCT Classic Site Preparation Guide
Micromass GCT Classic Site Preparation Guide
Waters GCT
Site Preparation Guide
Responsibilities ............................................................................................................. 4
Storage ......................................................................................................................... 5
Responsibilities
Warning: Observe Good Laboratory Practice (GLP) at all times, particularly when
working with hazardous materials, and consult the safety representative
for your organization regarding its protocols for handling such materials.
Warning: Safety glasses must be worn at all times when working with
hazardous materials and pressurized fluidics.
A Waters engineer will be responsible for installing and commissioning the system to ensure that
the instrument is properly installed and operational. The laboratory must be prepared in advance
to allow the engineer to carry out the installation efficiently. A site preparation checklist is included
at the end of this document for you to fill in and return to Waters when the laboratory is ready.
Important: The installation of the system cannot begin until the checklist has been completed
and returned.
The duration of the installation may vary, depending on the number of instrument options being
installed. The site preparation checklist should be completed as accurately as possible to help
minimize the installation time.
A major part of system installation is a series of tests which are used to evaluate the instrument
under specific operating conditions. The actual test result obtained, is recorded in the Installation
Checklist or Instrument Qualification Workbook, whichever is appropriate.
Important: An operator who has been designated to be responsible for the normal use and
upkeep of the instrument should be present during the installation.
The operator will assist with the instrument tests during the installation; this allows the operator
to be trained in the basic system operation. If there are foreseen periods when the intended
operator cannot be present, please notify us in advance; this will enable us to schedule the
installation for a more convenient time.
The instrument is supplied with a DB5-MS 30 m GC column. Please contact your Waters sales
representative if you wish Waters to supply any additional columns.
If you have any questions regarding the information in this document or any particular site
problems, please contact your local Waters sales representative. If necessary we will arrange to
carry out a site survey.
• Crates stored away from heavy machinery such as compressors or generators, which
generate excessive floor vibration
• Storage area temperature 0 to 40 °C (32 to 104 °F) and humidity <80%, non-condensing
Contact your local Waters representative if you need further advice regarding storage conditions.
It is a warranty condition that the shipping crates are unpacked only when the Waters engineer is
present.
If possible, provide an electrical screwdriver or drill with screwdriver attachment to assist with
opening the crates. At the end of the installation, it is the customer’s responsibility to dispose of
the crates and packaging.
It is essential that the instrument is not bumped or jolted during unpacking or any subsequent
transport. If the instrument needs to be transported across an uneven surface, the instrument
must be carried on a forklift truck or trolley.
Doorways must be at least 600 mm (24 in.) wide. Elevators and corridors (including corners) must
be sufficiently wide for maneuvering of the instrument. Special handling arrangements may be
necessary if access to the laboratory is via a staircase.
Data system
50 kg (110 lbs)
(computer, monitor and optional printer*)
Warning: The instrument must only be lifted using lifting equipment capable of raising the
instrument's weight safely. The instrument must not be lifted manually.
Important: It is essential that you provide suitable equipment for lifting the instrument. The
installation cannot be implemented unless this equipment is made available.
Do not attempt to unpack the shipping crate until the Waters engineer is present.
The engineer will require assistance lifting and positioning the equipment.
Caution: Do not attempt to lift the instrument by the front moulded cover, the probe, the GC
interface or the source housing.
A forklift truck or A-frame hoist is recommended for lifting and transporting the instrument.
The instrument is fitted with a lifting harness, which must be used to lift the instrument from the
shipping crate onto the bench.
As a general guide, before undertaking any lifting, lowering or moving of the instrument:
• Assess the risk of injury.
• Take action to eliminate the risk.
• Plan the operation in advance and in conjunction with the Waters engineer when they
arrive on site.
• Use trained personnel where necessary.
• Adhere to appropriate country and/or company regulations.
Instrument
The GCT mass spectrometer has a width of 567 mm (22.3 in), a length of 790 mm (31.3 in), and
a height of 450 mm (17.7 in). The instrument is mounted on four supporting feet.
The GCT may be installed on any flat surface. Allow the following minimum clearances around the
instrument for service access and ventilation (Figure 1):
• 200 mm (8 in) at the back or the front of the instrument (to allow the instrument to be
pulled forward), for servicing the electronics unit.
• 200 mm (8 in) behind the bench to allow for the bend radius of the vacuum pipes.
• 250 mm (10 in) on the right hand side of the instrument if a GC is fitted.
• 450 mm (18 in) between the GC and the GCT instrument if a solids probe is to be used.
A suggested bench layout for the GCT, data system, and GC is shown in Figure 1.
600 mm (23.6 in.)
200 mm
(7.9 in.)
Data System
567 mm
750 mm (22.3 in.)
(29.5 in.)
Rotary Pump
The rotary pump should be positioned either behind or underneath the instrument, and within 1 m
(39 in) of the rear of the instrument chassis. It is recommended the rotary pump be elevated 150
to 200 mm (6 to 8 in) above the floor to provide easy access during routine maintenance (e.g.
changing the pump oil).
GC System
Ensure that there is sufficient space to the right of the GCT to allow the GC to be pulled clear of
the GC interface line.
The data system must be located within 5 m (16 ft) of the mass spectrometer to enable the
communication cables to be fitted. The communication and power cables supplied with the
instrument, data system and the rotary pump are all 2 m (6.5 ft) long.
Note: Connections INSIGHT software directly communicates with the Waters Enterprise
Server using 128-bit data encryption. For further information see Connections
INSIGHT Frequently Asked Questions (p/n 720001131EN).
Electrical Safety
The GCT complies with the International Safety Standard IEC 61010-1:2001 and meets the
European Low Voltage Directive 2006/95/EC by means of European Harmonized Standard
EN 61010-1:2001.
For installations in Australia and New Zealand, the building installation must comply with AS3000:
electrical installations for Australia and New Zealand.
The instrument is suitable for use in environments categorized as Pollution Degree 2 and
Over-voltage Category II.
Power Requirements
Power Supply
The GCT requires two grounded (earthed) power sockets, one for the GCT and one for the rotary
pump. The maximum current consumption of the GCT is 6.0 A. The power supply sockets should
be located within 2 m (6.5 ft) of the instrument. Do not position the equipment so that it is
difficult to disconnect the mains cable.
110 to 120 V
100 to132 V 13 to 16 A 300 W
RV3 Rotary 60 Hz IEC 60320 C14
Pump 220 to 240 V receptacle
180 to 253 V - -
50 Hz
Important: Voltage supply stability is critical for instrument operation, the power supply
voltage must fall within the ranges specified in Table 2 at all times to avoid the risk
of instrument failure.
The supplies must be fused or fitted with circuit-breakers of the specified ratings, in accordance
with local regulations.
The mains supply must not have brown-outs/surges greater than ±10%, and must not exceed the
specified maximum operating range, for more than 0.3 sec. Transient voltage drops to half
nominal voltage or less must have a duration of less than 20 msec.
On pump start-up, currents of up to 32 A may be drawn for up to a second, due to the initial
pump loading. It is recommended that time delay fuses and circuit-breakers are used to prevent
nuisance tripping.
The backing pump is normally in continuous operation; it is recommended that the system be
installed such that the supply cannot be inadvertently switched off.
It is also recommended that additional protection is provided for the instrument by means of:
In the case of instruments fitted with a transformer, the RCD/GFCI must be fitted on the primary
(supply) side of the transformer.
If your order includes a nitrogen generator and the mains supply is known to run continuously at
voltages less than 220 V, Waters and Peak Scientific recommend fitting one of the following
transformers between the generator and mains supply.
Caution: Running nitrogen generators continuously at voltages less than 220 V is not
recommended and extended periods at these extremes can affect the operation
and life of the generator.
View
Computer equipment is typically rated at 100 to 120 V / 220 to 240 V, 50/60 Hz. In some cases,
it may be necessary to set the appropriate voltage using a voltage selector switch before
connecting the equipment to the power supply. For full details, refer to the instructions provided
with the equipment.
US/Canada (125 V)
US/Canada (250 V)
UK
3-pin
(BS1363)
Europe
2-pin
(CEE7) Data System
Mass Spectrometer
Rotary Pump
Denmark Nitrogen Generator
3-pin
(Afsnit 107-2-D1)
Australia
3-pin
(AS/NZS 3112)
China
GB2099
Data System
(10 A version)
China
Mass Spectrometer
GB2099
Rotary Pump
(16 A version)
Nitrogen Generator
These UPS units step up single-phase line voltage to 230 V AC, provide power conditioning and
protection for the MS system.
For North America, the UPS system requires one L6-30 (30 amp) wall socket. In other areas, the
UPS system will typically connect to your laboratory mains power using the standard MS
instrument power cord and wall socket required for your system. See Table 2 and Table 4.
305 mm
838 mm (33 in.) (12 in.)
813 mm
(32 in.)
One water inlet and one water outlet are required for the instrument. Reinforced flexible hose
10 mm ID should be used. A 5 m (16 ft) length is supplied with the instrument. The mains water
supply requirements are as follows:
Parameter Value
If mains water supplies are used, suitable in-line filters are required to remove particulate matter
and prevent blockage of the water pipes.
The water may be supplied by a recirculating chiller with the specifications shown in Table 6.
Parameter Value
These specifications assume that the outlet water temperature is no more than 30 °C (86 °F).
Note: Do not use an inlet water temperature of less than 15 °C (59 °F), as this may lead
to the formation of condensation on exposed pipe work.
Note: Operation above 2000 m (6500 ft) altitude may adversely affect the cooling of the
system.
Warning: The active exhaust vent must provide a minimum vacuum of 2 millibar
below atmospheric pressure (negative pressure). It must be capable of
supporting a maximum instrument exhaust gas load of 2000 L/hour.
Warning: Exhaust venting must comply with all local safety and environmental
regulations. The ANSI/AIHA Z9.2-2001 standard for “Fundamentals
governing the design and operation of local exhaust ventilation systems”
provides guidance on compliant exhaust systems.
Positioning
It is recommended that the instrument be installed in an air-conditioned laboratory, in a draft free
position, away from excessive amounts of dust and out of direct sunlight. Air-conditioning units
should not be positioned directly above the mass spectrometer.
Ventilation
The maximum overall heat dissipation into the room from the instrument and pump is
approximately 1.2 kW. This figure does not take into account ancillary equipment such as GC
systems. Air conditioning systems may have to be installed or upgraded to accommodate
additional heat load into the room when these systems are installed.
Caution: Waters recommends using a forced air exchange system in the laboratory; refer to
local safety regulations for examples of exchange rates required for hazardous
substances.
Temperature
The ambient temperature range required for normal operation is 15 to 30 °C (59 to 86 °F).
The ambient temperature range for operation must not exceed 5 to 40 °C (41 to 104 °F),
otherwise the performance will be reduced and the instrument may fail.
Humidity
The relative humidity must not exceed 70% for temperatures up to 31 °C (88 °F).
Vibration
The instrument should not be placed close to heavy machines such as compressors and
generators, which may generate excessive floor vibration.
Magnetic Fields
The instrument must be positioned away from magnetic fields of greater than 10 Gauss, such as
those generated by NMR spectrometers or magnetic sector mass spectrometers.
Radio Emissions
The instrument should not be placed within a Radio Frequency (RF) field of greater than 1.0 V/m.
Possible sources of RF emission include RF-linked alarm systems, Local Area Networks (LANs),
mobile telephones and hand-held transmitters.
Compressed Air
Compressed air at 7 bar (100 psi) is required for operating the instrument.
GC Carrier Gas
Caution: Ensure that there are no soldered or brazed joints in the line, as these may result
in contamination of the instrument with tin or lead oxide. Any joints in the nitrogen
line must be compression fittings.
Dry ultra high purity helium (99.999% or better, with less than 1 ppm H2O) is required. A Supelco
OMI2 purifier fitted with suitable shut-off valves is recommended. This may improve performance
with some analytes and increase column life.
Gases must be connected using clean 1/8 in chemically cleaned copper or medical grade stainless
steel tubing (not supplied) and checked for leaks under pressure. All gases must be regulated up
to 7 bar (100 psi) maximum; the pressure depends on the GC and current application.
For CI operation, methane, ammonia, and isobutane are recommended. Methane is required for
the installation procedure. Gases should be of a high purity (≥99.9%).
Gases must be connected using clean 1/8 in chemically cleaned copper or medical grade stainless
steel tubing (not supplied) and checked for leaks under pressure. All gases must be regulated at
0.7 bar (10 psi), [2.1 bar (30 psi) maximum]. Stainless steel pipe is required if ammonia is used.
A needle shut-off valve (Swagelok SS-OVS2 or similar) between the CI gas regulator and the CI
gas tubing is highly recommended to protect the diaphragm of the regulator when purging the
external CI gas inlet.
For additional GC options, such as Cryo cooling and FID, additional gases and regulators may be
required. Please contact your Agilent representative for details.
Exhaust Outlets
Note: Refer to the exhaust warnings in the Environmental Requirements section on
page 14 for additional exhaust information.
Five meters (16 ft) of 12 mm ID PVC tubing is supplied. If this length is insufficient, the user must
supply an adapter and tubing with an internal diameter of at least 51 mm (2 in.) for the extra
distance to the vent point.
Note: The fume hood/industrial vent must be equipped with an extraction fan system to
enable adequate displacement of the exhaust gases.
Warning: Hazardous samples must be handled with care and in a manner that
conforms to the manufacturers’ guidelines.
Test samples are required for verifying the operation of instruments at the time of installation;
they are also used for routine operations such as tuning and mass calibration. The compounds that
are used for testing the GCT are listed in Table 7.
Ionization probe*
Ionization Mode
Desorption
Desorption
Ionization
Ionization
Chemical
Chemical
Electron
probe*
Mode*
Mode*
Field
Field
Sample Supplier Code
2,4,6 Tris(trifluoromethyl)-1,3,5-
Fluorochem 001549
triazine
* Option
Note: The samples listed in Table 7 are not supplied with the instrument and should be
purchased by the customer prior to installation. Contact your local Water’s Sales
representative if you need assistance obtaining the necessary compounds
(www.waters.com).
Note: If your laboratory practices require full sample certification documentation, Waters
Analytical Standards and Reagents provide ready-to-use reference materials and
reagents that are fully traceable and certified (www.waters.com).
Important: The Waters engineer will not be carrying test samples to the installation.
Cleaning Equipment
An ultrasonic bath is required for the routine cleaning of instrument parts. The bath must be at
least 300 mm x 150 mm x 100 mm deep (12 in. x 6 in. x 4 in.).
Caution: Surfactants must not be used for cleaning glassware or other components. Refer to
®
the document Controlling Contamination in Ultra Performance LC /MS and
HPLC/MS Systems (p/n 715001307), located in the Support area of the Waters
website (www.waters.com).
Surfactant-free glass vessels are required in which to place instrument components for cleaning.
These vessels must be made available for use at the time of installation. The vessels must have a
diameter of at least 120 mm (5 in.) and be approximately 120 mm (5 in.) high.
Summary of Fittings
Table 8 shows a summary of the waste and gas connections for the installation of the GCT.
Note: If any items are on order, please indicate this on the checklist and include the
anticipated arrival date.
Note: It is the customer’s responsibility to ensure that all the correct laboratory supplies
are present. If you need any additional information or have difficulties acquiring
parts or samples, please contact your local Waters Sales representative.
Methane gas is available, regulated at 2 bar (30 psi) with a / in fitting for all CI options ..............
1
8
Compressed air supply is available, at 7 bar (100 psi) with a fitting for a 4 mm hose (supplied) .....
Clean, dry, inert gas is available, at 0.35 bar (5 psi) with a fitting a for a 4 mm hose
(supplied) ............................................................................................................................
Rotary Pump Exhaust (see page 16)
A suitable outlet is available for the rotary pump exhaust ..........................................................
GC System (see page 7)
The GC was purchased with the GCT mass spectrometer ...........................................................
or
Already
Make / Type Model To be commissioned on
commissioned
During the installation, the user intends to be available for demonstration and training by the
Waters engineer:
During the likely period of installation, the following dates are NOT convenient:
___________________________________________
Signed: ___________________________________________
*Important: If an authorized Waters service engineer arrives on site to begin installation work
and can not complete the installation due to lack of facilities (i.e. lifting equipment,
power, water, test samples, laboratory readiness), costs incurred will be charged to
the customer.
Name ________________________________________________
Position ________________________________________________
Organization ________________________________________________
Street ________________________________________________
City ________________________________________________
ZIP/Postcode ________________________________________________
Country ________________________________________________
Telephone ________________________________________________
Fax ________________________________________________
E Mail ________________________________________________
Important: The installation of your system cannot begin until pages 19 through 24 of this
document have been fully completed and returned to the Mass Spectrometer Sales
Support Representative at your local Waters office.
We would be grateful if you could take the time to complete the following questions to provide us
with some information about how the instrument will be used.
This information will enable us to inform you of relevant current application notes and seminars
and allows us to identify common interest groups so that we can promote cross transfer of
information between customers.
_______________________________________________________________________
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Our sales team often requires reference sites for specific applications.
Would you be willing to be used as a contact reference site for prospective customers?
_______________________________________________________________________
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