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    CT Public v82 8 9

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    Dida Herma
    This study compared 48 patients with papillary thyroid cancer located in the isthmus to 96 patients with papillary thyroid cancer located in the thyroid lobes. Cancers located in the isthmus were found to be more likely to have spread outside of the thyroid gland compared to cancers in the lobes (83% vs 66%). Ultrasounds also found that cancers in the isthmus were more likely to have features associated with spread outside the thyroid. The results suggest that papillary thyroid cancers in the isthmus have a higher risk of spreading and biopsies should be considered for all suspicious isthmus nodules.

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    CT Public v82 8 9

    Uploaded by

    Dida Herma
    27 views2 pages
    This study compared 48 patients with papillary thyroid cancer located in the isthmus to 96 patients with papillary thyroid cancer located in the thyroid lobes. Cancers located in the isthmus were found to be more likely to have spread outside of the thyroid gland compared to cancers in the lobes (83% vs 66%). Ultrasounds also found that cancers in the isthmus were more likely to have features associated with spread outside the thyroid. The results suggest that papillary thyroid cancers in the isthmus have a higher risk of spreading and biopsies should be considered for all suspicious isthmus nodules.

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    This study compared 48 patients with papillary thyroid cancer located in the isthmus to 96 patients with papillary thyroid cancer located in the thyroid lobes. Cancers located in the isthmus were found to be more likely to have spread outside of the thyroid gland compared to cancers in the lobes (83% vs 66%). Ultrasounds also found that cancers in the isthmus were more likely to have features associated with spread outside the thyroid. The results suggest that papillary thyroid cancers in the isthmus have a higher risk of spreading and biopsies should be considered for all suspicious isthmus nodules.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    27 views2 pages

    CT Public v82 8 9

    Uploaded by

    Dida Herma
    This study compared 48 patients with papillary thyroid cancer located in the isthmus to 96 patients with papillary thyroid cancer located in the thyroid lobes. Cancers located in the isthmus were found to be more likely to have spread outside of the thyroid gland compared to cancers in the lobes (83% vs 66%). Ultrasounds also found that cancers in the isthmus were more likely to have features associated with spread outside the thyroid. The results suggest that papillary thyroid cancers in the isthmus have a higher risk of spreading and biopsies should be considered for all suspicious isthmus nodules.

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    of 2

    CLINICAL THYROIDOLOGY FOR THE PUBLIC

    A p u b l i c a t i o n o f t h e A m e r i c a n T hy ro i d A s s o c i a t i o n

    THYROID CANCER
    www.thyroid.org
    Cancers in the thyroid isthmus are more likely to spread
    outside of the thyroid
    BACKGROUND The cancers located in the isthmus showed a higher
    The thyroid gland is shaped like a butterfly with two frequency of the cancer spreading outside of the thyroid
    wings or lobes on either side of the windpipe that are as compared with cancers located in the lobe (83% vs.
    joined together by a bridge of tissue, called the isthmus, 66%). Both groups showed no differences in term of
    which crosses over the front of the windpipe. Most thyroid other prognostic factors. Ultrasound imaging showed that
    cancers are found in the lobes and only 2-9% of cancers cancers located in the isthmus were associated with a higher
    are located in the isthmus. Investigators have reported that incidence of the following features than tumors located in
    cancers in isthmus are more likely to spread outside of the lobes: wider-than-tall shape (91.7% vs. 56.3%) and
    the thyroid. While overall prognosis of papillary thyroid ultrasound findings suspicious for tumor spreading outside
    cancer is good, the prognosis of patients with cancer the thyroid (93.8% vs. 53.1%). In addition, in the group
    spreading out of the thyroid is less favorable. Specific of patients with spread of the cancer to the lymph nodes,
    ultrasound features of nodules are suspicious of cancer cancers located in the lobe tended to associate with lymph
    like: taller-than-wide shape, an irregular margin, markedly node spread at the same side of the cancer (84.6%), whereas
    dark appearance and microcalcifications. However, these patients with isthmus cancers tended to have lymph node
    findings are based on cancers located in the thyroid involvement on the both sides of the neck (50%).
    lobes and so far there are no reports on characteristics
    of suspicious nodules located in the isthmus. This study WHAT ARE THE IMPLICATIONS
    examined ultrasound characteristics of papillary thyroid OF THIS STUDY?
    cancer located in the isthmus as compared to cancers The results of this study suggest that papillary thyroid
    located in the thyroid lobes. cancers located in the isthmus are more likely to spread
    outside of the thyroid than cancers located in the lobes.
    THE FULL ARTICLE TITLE Because of these findings, a biopsy should be performed in
    Hahn SY et al. Ultrasound findings of papillary thyroid all isthmus nodules with suspicious findings by ultrasound
    carcinoma originating in the isthmus: comparison with and special attention should be paid to search for
    lobe originating papillary thyroid carcinoma. AJR Am J abnormal lymph nodes on both sides of the neck.
    Roentgenol 2014;203:637-42. — Jamshid Farahati MD

    SUMMARY OF THE STUDY ATA THYROID BROCHURE LINKS


    At total of 48 patients with papillary thyroid cancer Thyroid cancer: http://www.thyroid.org/
    located in the isthmus and 96 patients with papillary cancer-of-the-thyroid-gland
    thyroid cancer located in lobes were identified between Thyroid Surgery: http://thyroid.org/patients/patient_
    2007 and 2008. All the patients had undergone preop- brochures/surgery.html
    erative ultrasound of the neck, total thyroidectomy with
    Thyroid Nodules: http://www.thyroid.org/
    bilateral central-lymph-node dissection and postoperative
    what-are-thyroid-nodules
    follow-up for at least 2 years.

    ABBREVIATIONS & DEFINITIONS

    Thyroid nodule: an abnormal growth of thyroid cells thyroid nodules are non-cancerous (Benign), ~5% are
    that forms a lump within the thyroid. While most cancerous.

    Clinical Thyroidology for the Public (from recent articles in Clinical Thyroidology) Volume 8    Issue 2    2015    8
    Back to Table of Contents
    CLINICAL THYROIDOLOGY FOR THE PUBLIC
    A p u b l i c a t i o n o f t h e A m e r i c a n T hy ro i d A s s o c i a t i o n

    THYROID CANCER, continued


    www.thyroid.org

    Thyroid Ultrasound: a common imaging test used to Microcalcifications: Small flecks of calcium within a
    evaluate the structure of the thyroid gland. Ultrasound thyroid nodule, usually seen as small bright spots on
    uses soundwaves to create a picture of the structure ultrasonography. These are frequently seen in nodules
    of the thyroid gland and accurately identify and containing papillary thyroid cancer.
    characterize nodules within the thyroid. Ultrasound is
    also frequently used to guide the needle into a nodule Papillary thyroid cancer: the most common type of
    during a thyroid nodule biopsy. thyroid cancer.

    Thyroid fine needle aspiration biopsy (FNAB): a simple Total thyroidectomy: surgery to remove the entire
    procedure that is done in the doctor’s office to determine thyroid gland.
    if a thyroid nodule is benign (non-cancerous) or cancer.
    The doctor uses a very thin needle to withdraw cells Cancer recurrence: this occurs when the cancer comes
    from the thyroid nodule. Patients usually return home or back after an initial treatment that was successful in
    to work after the biopsy without any ill effects. destroying all detectable cancer at some point.

    Clinical Thyroidology for the Public (from recent articles in Clinical Thyroidology) Volume 8    Issue 2    2015    9
    Back to Table of Contents

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