Com Science Biology Section Notes
Com Science Biology Section Notes
Com Science Biology Section Notes
MR MOYO DUMISANI
Page |1
This section on laboratory rules and safety is not part of the main syllabus ordinary level
section, but it has been added to remind the learners of the importance of order and safety
in the laboratory
1.0 LABORATORY RULES AND SAFETY
Natural sciences are generally practical fields of study; of which they require
specialized rooms for the sake of their study.
These are called Science Laboratories
The kind instruments and materials found inside the laboratories vary as per subject
specification of which that room is built for.
These laboratories are usually associated with storerooms that have chemicals, and gas
cylinders are usually attached to them of which they contain gases.
Therefore, there are rules and regulations that govern the use of these rooms, i.e.
laboratory rules
1.1 LABORATORY RULES
1. Report all accidents, injuries, and breakage of glass or equipment to instructor
immediately.
2. Keep pathways clear by placing extra items (books, bags, etc.) on the shelves or under
the work tables. If under the tables, make sure that these items cannot be stepped on.
3. Long hair (chin-length or longer) must be tied back to avoid catching fire.
4. Wear sensible clothing including footwear. Loose clothing should be secured so they
do not get caught in a flame or chemicals.
5. Work quietly — know what you are doing by reading the assigned
experiment before you start to work. Pay close attention to any cautions described in
the laboratory exercises
6. Do not taste or smell chemicals.
7. Wear safety goggles to protect your eyes when heating substances, dissecting, etc.
8. Do not attempt to change the position of glass tubing in a stopper.
9. Never point a test tube being heated at another student or yourself. Never look into a
test tube while you are heating it.
10. Unauthorized experiments or procedures must not be attempted.
11. Keep solids out of the sink.
12. Leave your work station clean and in good order before leaving the laboratory.
13. Do not lean, hang over or sit on the laboratory tables.
14. Do not leave your assigned laboratory station without permission of the teacher.
15. Learn the location of the fire extinguisher, eye wash station, first aid kit and safety
shower.
16. Do not lift any solutions, glassware or other types of apparatus above eye level.
17. Follow all instructions given by your teacher.
18. Learn how to transport all materials and equipment safely.
19. No eating or drinking in the lab at any time
2.3
2.3 STRUCTURE OF THE PLANT AND ANIMAL CELLS
structure function Animal cell Plant cell
Nucleus -contains hereditary information Present Present
-controls the activities of the cell
cytoplasm -liquid part were cell organelles are suspended Present Present
-Site for chemical reactions
cell membrane -partially permeable Present present
-allows certain substances in, and others out
mitochondria -site for respiration in the cell Present Present
-responsible for energy production
cell wall -permeable Absent Present
-made of cellulose
-maintains the rigid structure
vacuole -contains salts and other dissolved minerals Small Large
-responsible for maintenance of the osmotic temporary permanent
potential of the cell
-responsible for thee vacuolar pathway
chloroplasts -contains chlorophyll which is stored in the Absent Present
grana
RESULTS/OBSERVATIONS
Positive test, colour changes from brown to blue-black
At times, the final colour is not blue-black, but a bit off from the expected, except if you
use the leaf from a geranium (Pelargonium) plant
Negative test, colour remains brown
it might be distorted by of the food sample
CONCLUSION
Positive test, starch was present
Negative test, starch was absent
3.5.1 CHLOROPHYLL
AIM
To test whether chlorophyll is necessary for photosynthesis or not
APPARATUS AND CHEMICALS
1. Lab apparatus
2. Potted plant with variegated leaves
These are leaves that have two sections, the other green and the other off-white
METHOD IN STEPS
1. De-starch the plant
Place it in a dark cabinet for about 24-48hours for the plant to use all the starch
2. Place the plant back in sunlight for 6-12 hours
This induces starting of photosynthesis, producing starch again
3. Test the leaf for starch
RESULTS/OBSERVATIONS
The green region turns blue black
The off-whitish region is colour brown
CONCLUSION
Chlorophyll is needed for photosynthesis
A conclusion is actually a re-phrasing of the aim, or rather, an answer of the aim
3.5.2 SUNLIGHT
AIM
To test whether sunlight is needed for photosynthesis
APPARATUS AND CHEMICALS
1. Lab apparatus
2. Aluminum
3. Potted plant
This is basically a planted plant
METHOD IN STEPS
1. De-starch the plant
2. Fasten the aluminum foil on half part of the plant
The aluminum foil with prevent sunlight from reaching the covered region
3. Expose the plant to sunlight for 6-12 hours
4. Pluck the leaf and test for starch
RESULTS/OBSERVATIONS
The region with the aluminum foil, iodine remains brown
The region exposed to sunlight, iodine turns from brown to blue-black
CONCLUSION
Sunlight is needed for photosynthesis
3.5.3 CARBON DIOXIDE
AIM
To test whether carbon dioxide is necessary for photosynthesis
APPARATUS AND CHEMICALS
1. Lab apparatus
2. Polythene bag
3. Calcium hydroxide/lime water
4. Potted plant
METHOD IN STEPS
1. De-starch the plant
2. Tie one plant into a polythene bag which has lime water (calcium hydroxide)
Polythene bag keeps inside gases in, calcium hydroxide will absorb the carbon dioxide
Calcium hydroxide + carbon dioxide calcium carbonate
3. Expose the plant to sunlight for 6-12 hours
4. Pluck one leaf from inside the polythene bag, and the other from outside (control) and
test for starch
RESULTS/OBSERVATIONS
Positive test (iodine turns from brown to blue-black) on the leaf from outside the
polythene bag
Negative test (iodine remains brown) from the leaf inside the bag
CONCLUSION
Carbon dioxide is necessary for photosynthesis
4.0 ECOSYSTEMS
An ecosystem is the interaction of organisms and their physical environment
4.1 COMPONENTS OF AN ECOSYSTEM
Components of an ecosystem
Biotic (living components) Abiotic (non-living components)
Plants Rocks, soil and stones
Animals Water
Air
Examples of a
a. Food chain
Interconnection of organisms per their feeding
It always starts with a producer and ends with a decomposer
For example
Producer primary consumer secondary consumer decomposer
Grass cow man maggots
b. Food web
Interconnection of food chains, one stage of feeding can have many organisms
contained within
Grass human
Cow maize
Lion maggots
c. Pyramid of biomass
Biomass is the dry mass of an organism #
Its arranged in a pyramid of trophic levels, with the lowest level having the
producers, and the highest having the last consumer
4.5.1 BIODIVERSITY
Collection of different species of organisms per given environment
4.5.2 EFFECTS OF LIMITED BIODIVERSITY
Limited food provisions for other organisms in the ecosystem
Less species of organisms means less productivity
Less pressure on the land for resources, if populations can be controlled
5.5 DIGESTION
Point of Description Mechanical Chemical digestion
digestion of the digestion Enzyme/chemical Process catalysed
structure
mouth -teeth -teeth grinds food Salivary amylase Starch to maltose
-tongue from big insoluble
-salivary molecules to small
glands that soluble molecules
secrete -tongue mixes food
saliva with saliva an rolls
food into a bolus
Oesophagus longitudinal -peristalsis Salivary amylase Starch maltose
and smooth
muscle
Stomach -glandular -churning mixing with Hydrochloric acid Pepsinogen to pepsin
lining being stomach juices, -produced by the Hydrolyses of
protected by producing chime glandular lining of sucrose to glucose
an epithelial which is sent into the the stomach and fructose
lining duodenum -it destroys
-produces bacteria
enzymes Renin Coagulation of milk
and the HCl Pepsin Proteins peptones
Duodenum Epithelial Bile (produced by -Emulsify fats
lining liver stored in the -neutralises stomach
gall bladder) acid
Maltase Maltose glucose
(pancreatic juice)
proteases Peptones amino
(pancreatic juice) acids
Lipase (pancreatic Fat fatty acids and
juice) oils
5.5 ABSORPTION
It begins in the ileum and ends at the large intestines
NB a little absorption happens in the jejunum, but usually it is considered to begin in
the ileum
5.5.1 ROLE OF THE ILEUM
Structure Function
Long Affords a large surface area for absorption
One cell thick Allow faster diffusion of ions and nutrients into the blood
system
Has villi Increase surface area for absorption of nutrients
Associated with many To transport the diffused nutrients and ions
capillaries
The blood with the absorbed nutrients are carried by the hepatic portal vein from the
gut to the liver
The liver will regulate the amount of substances and nutrients in the blood
5.5.2 ASSIMILATION
Component Product Uses in animals If in excess
after
digestion
Carbohydrates Glucose -substrate for cellular 1st converted to glycogen (stored in
respiration the liver 250g)
-formation of chitin, an 2nd converted to fat and stored in the
exoskeleton for some adipose tissue (under the skin)
organisms 3rd if adipose tissue if full, it then
accumulates around the vital organs
Proteins Amino -used for protein synthesis Amino acids are de-aminated to
acids Formation of non-amino acids form urea and carbohydrate
Urea forms urine and the
carbohydrate is used for respiration
Vitamins Vitamin A Eye sight and respiratory Excreted
tissues
Vitamin C Blood vessel development
Vitamin D -aids in absorption of calcium
in bones
Fats, oils and Fatty acids Used in formation of cell Stored in the form of fats
lipids membranes
Glycerol Can be used as a respiratory
substrate
Mineral ions Calcium Strengthening of bones and Excreted
teeth
Iron Formation of the haem group
in the hemoglobin
Iodine Formation of thee growth
hormone
Fiber cellulose Prevents constipation Excreted
Water water Aqueous medium for chemical Excreted
reactions in the body
5.7 Food tests for starch, simple sugars, protein and fats
5.7.1 Starch
AIM
To test for the presence of starch in a food sample
APPARATUS AND CHEMICALS
Lab apparatus
Food sample
Iodine solution
METHOD IN STEPS
1. Place the food sample on a white tile
if the food sample is a solid, crush, if it’s a solution, pour it in a beaker and place the
beaker of a white tile
2. Add drops of iodine
use a dropper for this process
3. Observe colour changes if any
At times, colour changes are not clear, you must be observant
RESULTS/OBSERVATIONS
Positive test, colour changes from brown to blue-black
At times, the final colour is not blue-black, but a bit off from the expected, except if you
use the leaf from a ________________ tree
Negative test, colour remains brown
it might be distorted by of the food sample
CONCLUSION
Positive test, starch was present
Negative test, starch was absent
5.7.2 REDUCING SUGARS
AIM
To test for the presence of reducing sugars in a food sample
APPARATUS AND CHEMICALS
Lab apparatus
Benedict’s solutions
Water bath
METHOD IN STEPS
Dissolve the food sample in water
If the food sample does not dissolve in water, first dissolve in ethanol, then add to water
Add benedict’s solution
Warm gently in a water bath
RESULTS/OBSERVATIONS
Positive test, blue yellow orange brick-red
This test can be used to test for the difference in concentrations of the reducing sugars
Different colour transitions will give you different colour changes
Negative test, solution remains blue
Colour of thee food sample must be clear so as to observe colour changes well
CONCLUSION
Reducing sugars were present
Testing for glucose using a clinistix
A clinistix is a strip of paper that is pink in colour.
It is dipped into the food solution and if glucose is present, the clinistix will
change colour from pink to purple. The purple colour shows a positive test for
glucose.
If glucose is not present, the clinistix remains pink. This is a negative test to
glucose.
5.7.3 PROTEIN
AIM
to test a food sample for
APPARATUS AND CHEMICALS
1. laboratory apparatus
2. copper sulphate
3. sodium hydroxide
4. food sample
METHOD IN STEPS
1. dissolve food sample into 10ml of water
2. add 5ml of sodium hydroxide, then 5ml of copper sulphate
RESULTS/OBSERVATIONS
positive test, colour change from blue to purple colour.
Negative test, the solution remains blue.
CONCLUSION
Test for proteins using an albustix
An albustix is a strip of paper which is yellow in colour.
A solution of the food to be tested is prepared and an albustix is dipped into the
food solution.
If the food contains proteins, the albustix will change colour from yellow to green.
Green shows a positive colour for proteins.
If the albustix remains yellow, then there is no protein in the food.
5.7.4 FATS
Testing for fats
Fats can be tested using either the spot test or the emulsion test.
Structure Function
Nose Allow air in, ciliated with mucus to trap dust and micro
organisms, warm the air
Voice box Allow passage of air
Trachea Cartilage structure, ciliated to trap dust and micro organisms
Bronchus and bronchioles Channel air into the lungs, mucus and cilia to trap dust and
micro organisms
Alveoli Gaseous exchange
ribs protect lungs from puncture
When the blood reaches the alveolus, the carboxyhemoglin breaks down giving out
carbon dioxide.
The carbon dioxide diffuses into the alveolus, then the oxygen diffuses into the blood
stream, into the red blood cell, forming oxy-hemoglobin
Then the blood is transported back to the heart by the pulmonary vein
Structure Function
Many Increase surface area for absorption
Surrounded by capillaries Easier diffusion of gases to and fro the blood system
Moist Easier diffusions
Thin walled (one cell thick) Partially permeable for diffusion of air only to take place
NB The set-up must be done under water to avoid formation of bubbles in the water
column
7.3 FACTORS AFFECTING RATE OF TRANSPIRATION
7.3.1 LIGHT INTENSITY
An increase in light intensity results in the increase of rate of transpiration due to
an increase in stomata opening.
As light intensity increase, more water is lost, guard cells become flaccid and close
the stomata
7.3.2 TEMPERATURE
Plants transpire faster at higher temperatures; this is because the rate of evaporation
increases with temperature.
Same effect as light intensity
Temperature also reduces air humidity, so transpiration increases
7.3.3 HUMIDITY
7.3.4 WIND
-when you put a cell in a hypertonic solution, -when you put a cell in a hypotonic solution,
it loses water, the vacuole shrinks, and the it will gain maximum water, the vacuole
cell seems to collapse enlarges pushing against the cell membraned
-The cell wall maintains its shape which is kept in shape by the cell
-the cell wall will prevent the cell from
bursting
The heart is made of a special type of muscle called cardiac muscle which
contracts and relaxes regularly, throughout life.
The heart’s muscle is constantly active, so it needs its own blood supply, through
the coronary artery, to provide it with oxygen and glucose.
Valves in the heart prevent blood from being pushed backwards up into the atria
when the heart ‘beats’.
Semi lunar valves at the bottom of the aorta and pulmonary artery prevent the
back flow of blood into the ventricles when the muscles of the heart relax.
leaves the left side of the heart, goes into the aorta
in the aorta, it has the maximum pressure, rich in oxygen and nutrients needed by the
body cells for their metabolism
the aorta branches into target arteries which will transport the blood to specific organs
for example, the hepatic artery will carry blood to the gut
upon reaching the target organs, the target arteries branch into finer capillaries which
will manage to reach the individual cells
when blood reaches the cells, blood plasma seeps out bathing the cells forming tissue
fluid, the nutrients diffuse into the cells, and the oxy-hemoglobin complex breaks
down releasing oxygen
waste products diffuse into the blood, and carbon dioxide forms the carboxy-
hemoglobin with hemoglobin in the red blood cells
capillaries rejoin forming the target veins, target veins join to form the vena cava
the vena cava will transport the blood into the right atrium
when the right ventricle relaxes, blood flows into it
when the right ventricle contracts, blood is pushed out of the ventricle, but it cannot
go back into the atrium, because the atrioventricular valve has closed, so the blood is
forced into the pulmonary artery,
it is the only artery that carries de-oxygenated blood
pulmonary artery carries blood into the lungs, there in the lungs, carboxy-hemoglobin
breaks down releasing carbon dioxide, and oxyhemoglobin is formed
blood leaves the lungs via the pulmonary vein, going to the left side of the heart
it is the only vein that carries oxygenated blood
the oxygenated blood goes into the left atrium, pushed into the left ventricle when the
atrium contracts
it is pushed into the aorta when the ventricles contracts, thus the cycle continues
NB: All arteries carry oxygenated blood except the Pulmonary Artery which has de
oxygenated blood. All veins carry de oxygenated blood except the Pulmonary Vein
which carries Oxygenated Blood.
STRUCTURE FUNCTION
Stigma Receives pollen grains during the process of pollination
Produces a sticky substance to ensure pollen grains get stuck
Style Supports the stigma
Provides pathway for pollen tube to the ovules
Ovary Produces ovules, develops into fruit after fertilisation
Ovule female sex cells
Develops into a seed after the process of fertilisation
Petals Attract insects for pollination by their bright colour and nice scent
Their shape promotes pollination as they direct insects towards the
nectaries
Sepals Protects the flower bud
Anther Produces pollen grains
Pollen grains These are the male sex cells
Petals Petals are bright and produce a Dull coloured, usually green or brown
nice scent to attract insects and produce no scent as there is no need
to attract insects
Size of pollen Produce large sticky pollen Produce small smooth pollen grains
grains grains which are light enough to be carried by
the wind
9.5 GERMINATION
This is the process when seeds mature to produce plants
The plumule develops into leaves, and the radicle into leaves
The starch in the seed is used for respiration, producing the energy needed to germinate
the seed
Moisture softens the testa, thus allowing oxygen and to enter and help in respiration
9.6 CONDITIONS NECESSARY FOR GERMINATION
Moisture and oxygen are needed for germination
9.7 PERCENTAGE GERMINATION
10.3 FERTILIZATION
Fusion of the male and sex cell’s nucleus
Sperms are made in the testes then stored in the epididymis, 2oC below body temperature
When the glans penis has been sensitized, spasm are induced to release the sperms
They move from the epididymis into the sperm duct where seminal fluid is added from the
seminal vesicles, thus forming semen
From there, semen passes into the urethra, out onto the acidic vagina
The vagina is acidic so as to destroy bacteria that might accumulate in there
Sperms survive this acidic condition because of the alkaline condition of the semen
The sperms swim from the vagina, through the cervix, right into the womb, until they
reach the ovum
One sperm fertilizes one ovum, resulting in formation of a zygote
There is no multiple fertilization
Identical twins are a result of cell division, whereas fraternal twins and multiple births
are a result of multiple ovulation
When the zygote divides forming a ball of cells, then implants onto the uterus wall, it
becomes and embryo
Ectopic pregnancy is when the zygote implants onto the fallopian tubes
10.4 PREGNANCY,
When all the limbs have formed, it is now a fetus
Growth is increase in number of cells
Phase Period of time Description
embryo Implantation - -no distinct limbs
-Placenta is formed
-The heart is the first to be formed
-formation of the amniotic sack containing amniotic
fluid protecting the fetus against mechanical stress from
outside
Fetus -birth -Sex of the fetus is evident
-Libs are now distinct
-Other organs form
10.5 PLACENTA
Connects the fetus to the mother
Nutrients are transported across the placenta
Produces progesterone during pregnancy, this hormone is meant to maintain the uterine
wall throughout pregnancy
Blood from the mother does not mix with that of the fetus, to avoid coagulation and
infection, also to protect the under-developed fetal blood system from the high pressure
of the mother’s system
There is no HIV infection whilst in womb, except during birth
For positive expecting mothers, nevirapine or PEP drugs is given to prevent mother to
child transmission
10.8 CHILD CARE
10.8.1 BREASTFEEDING
10.8.1.1 WHAT IS BREASTFEEDING
Use of mammary glands that produce milk suckled by the baby/infant
10.8.1.2 ADVANTAGES OF BREASTFEEDING
Breastmilk contains colostrum, which is a cocktail of antibodies to act as passive
immunity for the developing baby
Breast milk contains balanced nutrients for the baby.
1. The milk contains antibodies which help to protect the baby against diseases. (breast
milk gives the baby natural passive immunity against diseases)
2. Breast feeding creates a close bond between the mother and the child.
3. The mother’s milk is clean and hygienic (it is free from pathogens except HI Virus for
positive mothers)
4. The milk is always at the correct temperature required by the baby.
5. It is cheap and is always available.
6. Breast feeding increases child spacing by mothers and is good for family planning.
10.9 CONTRACEPTION
Ways to prevent pregnancy
Type examples description advantages Disadvantages Side effects
Barrie Condoms Female (femidom)-Prevents both -reduce sensation -non
r Male pregnancy and -can burst
Thin rubber STIs
-no need for
prescription
Can be used with
other methods
Diaphrag Rubber cap covering -Can be re-used -Trained -induce
m Dutch the cervix, used with for 2 years personnel to discomfort
cap spermicide -no health administer it Irritation of
concerns yet -Inserted before spermicide
sex
-Less effective
with wrong size
Loop Small plastic coated It has a string to Can be painful Discomfort
(IUD) copper coil preventing remove Induce bleeding Bleeding of the
implantation Long lasting and cervical uterine
97-98% effective cancer
Horm Contracep mini pill having -99% effective -Daily intake -Weight gain
onal tive pill progesterone preventing -reversible -Suppress -mood swings
implantation
Combined pill with
-easy to use breast milk -breast
ostrogen and progesterone Menstrual -Increase risk of tenderness
prevents ovulation bleeding is normal heart attack >35 -causing
-Blood clots spotting
levonogest Prevents implantation Self-administered Must be taken -can develop
rel 99% effective as early as resistance over
possible time
2. Day 5~12:
Grafian follicle matures
Oestrogen is produced by the maturing grafian follicle
Oestrogen is to repair the uterine wall
3. Day 13/14/15:
The luteinising hormone is released by the pituitary gland, triggering the release of the
female sex cell
4. Day 15~28:
The follicle hardens and then produces progesterone which keeps the uterus lining
thick for possible embryo implantation.
5. Day 28
a. Scenario 1: ovum is not fertilized:
the hardened follicle degenerates, causing a fall in the levels of progesterone
and the uterus lining collapses
Menstruation is the removal of the unfertilised egg and uterus lining from the
body and last for 3 – 5 days.
At this point we go back to day 1, the process starts all over again.
b. Scenario 2: Egg is fertilized:
If ovum is fertilised, then implantation occurs.
The hardened follicle remains intact and continues producing progesterone
thus maintaining the uterine wall
10.11 INFERTILITY
10.11.1 CAUSES OF INFERTILITY
1. Low sperm count
Less sperms produced, in a normal ejaculation, an average of 3 million might
be produced
2. Poor sperm and semen quality
Deformed sperms, insufficient seminal fluid to neutralise the acidic vagina
3. Physical conditions
Cancerous growth in the fallopian tube or cervix
Prostate cancer
4. STIs
For example, gonorrhea can block the oviduct and sperm ducts
5. Hormonal imbalances in females
These induce menstrual disorders
10.11.2 WAYS TO CONCEIVE WHILST INFERTILE
1. Artificial insemination
The sperms are administered artificial through injection into the uterus
2. In-vitro fertilisation
Multiple ovulation is induced, the ova are collected and fertilised in a test-tube
Then the fertilized ovum is injected back into the womb
3. Fertility drugs
Drugs to enhance fertility, especially for women, those containing follicle
stimulating hormone and luteinising hormone
Your fingernails and toenails aren’t immune from the effects of smoking. Smoking
increases the likelihood of fungal nail infections.
Hair is also affected by nicotine. An older study found it increases hair loss, balding,
and graying.
DIGESTIVE SYSTEM
Smoking increases the risk of mouth, throat, larynx, and esophagus cancer. Smokers
also have higher rates of pancreatic cancer. Even people who “smoke but don’t inhale”
face an increased risk of mouth cancer.
Smoking also has an effect on insulin, making it more likely that you’ll develop insulin
resistance. That puts you at increased risk of type 2 diabetes and its complications,
which tend to develop at a faster rate than in people who don’t smoke.
SEXUALITY AND REPRODUCTIVE SYSTEM
Nicotine affects blood flow to the genital areas of both men and women. For men, this
can decrease sexual performance. For women, this can result in sexual dissatisfaction
by decreasing lubrication and the ability to reach orgasm. Smoking may also lower sex
hormone levels in both men and women. This can possibly lead to decreased sexual
desire.
10.3.1.2 HOW TO DEAL WITH ADDICTION
Therapy
Finding other recreational techniques like sports
10.3.2 ALCOHOL ABUSE
10.3.2.1 SIGNS AND SYMPTOMS OF ALCOHOL USE AND ABUSE
A high concentration of alcohol in the blood causes symptoms, such as
1. slurred speech
2. slowing of reflexes
3. a decreased ability to control bodily movements
4. difficulty concentrating
5. gaps in memory, or brownouts
6. poor decision-making abilities
7. risky behavior
8. staying conscious but not having memory of your actions, which is called a blackout
9. breathing problems, coma, or death.
10. Many people use alcohol with no ill effects. But anyone can experience its
effects, such as illness, vomiting, or hangovers.
Drinking alcohol can also lead to:
1. Accidents
2. falls
3. drowning
4. fighting
5. suicide
You shouldn’t attempt to drive or operate heavy machinery whilst under the influence of
alcohol. Also, refrain from engaging in social conversations that may be controversial as
they may easily turn into fights, then your wellbeing is compromised.
drinking to relax
driving under the influence of alcohol
problems with family and friends because of drinking
neglecting responsibilities
having legal problems because of alcohol
10.3.2.2 HOW TO DEAL WITH ADDICTION
Therapy
Finding other recreational techniques like sports
10.3.3 MANDRAX ABUSE
First used to treat psychosis
10.3.3.1 HEALTH EFFECTS
Reduced heart rate
Increased sexual arousal
Parenthesis (numbness of the fingers and toes)
Slurred speech
Headaches
Convulsions
Death through cardiac or respiratory arrest
10.3.3.2 HOW TO DEAL WITH ADDICTION
Rehabilitation therapy
detox
10.3.4 CANNABIS ABUSE
Euphoria, Relaxation, Drowsiness, Altered sense of time, Impaired memory, Slowed
reflexes and impaired motor skills, Bloodshot eyes, Increased appetite, Dry mouth,
Increased heart rate, Cognitive impairments, Paranoia.
10.3.4.1 HEALTH EFFECTS
Respiratory problems: Marijuana smoke has many of the same irritating and lung-
damaging properties as tobacco smoke. Long-term users may develop a chronic cough
and are at higher risk of lung infections.
Cardiovascular risk: Marijuana ingestion increases the heart rate for several hours,
increasing the chance of heart attack or stroke. This may aggravate pre-existing heart
conditions in long-term users and those who are older—placing them at greater risk of
a cardiovascular event.
Mental health effects: Long-term marijuana use can decrease an individual’s
performance on memory-related tasks and cause a decrease in motivation and interest
in everyday activities. Marijuana is also known to intensify symptoms in users with
schizophrenia.
Child development: Marijuana use during pregnancy can affect the development of the
fetus’s brain and has been linked to behavioral problems in babies.
Psychological dependence: Like most other drugs of abuse, individuals who use
marijuana for long periods of time can develop a dependence on it. Signs of dependence
in a user include the need to use marijuana to cope with everyday tasks and the
experience of cravings and anxiety when marijuana is not available.
10.3.4.2 HOW TO DEAL WITH ADDICTION
Rehabilitation therapy
detox
10.3.5 SOLVENTS ABUSE
Substances called hydrocarbons can be sniffed from glues, petrol, dry cleaning fluids,
typing correction fluid, nail polish and remover, and propellant gas from aerosols.
Most sniffers sniff directly from the bottle or tube; others use a plastic bag held over
their mouth.
When inhaled, they give an effect similar to alcohol, which includes:
1. Euphoria, then dizziness with blurring of vision, followed by feelings of unreality,
disorientation and irregular, jerky movements.
2. Visual hallucinations.
3. Stomach cramps.
4. Acute intoxication comes on very suddenly and disappears quickly once sniffing
stops. A mild hangover may be experienced.
10.3.5.1 HEALTH EFFECTS
Risks include death from inhalation of vomit, from an accident or from an irregular
heartbeat.
Solvents can cause acute kidney, liver and brain damage, related to individual
susceptibility rather than amount inhaled.
Anti-social behavior is also common amongst adolescents who abuse solvents.
10.3.5.2 HOW TO DEAL WITH ADDICTION
Therapy
Detox
11 IMMUNITY
Prevention of infection of the body
11.1 TYPES OF IMMUNITY
Type of DESCRIPTION OF HOW IT OCCURS
immunity
Passive Colostrum in breast milk contains live antibodies
No memory cells are formed
Active Live antibodies are injected
No memory cells formed
Natural Antibodies produced by the body upon infection
Memory cells formed
Artificial Vaccinations, injection of live or weak antibodies, to mimic an infection
Memory cells formed
In Zimbabwe, children below the age of five are immunized against the six child killer
diseases namely,
1. Whooping cough
2. Diphtheria
3. Measles
4. Polio
5. Tetanus
6. Tuberculosis
HIV is the seventh, though sadly, no effective vaccine has been discovered yet
11.2 ROLE OF WHITE BLOOD CELLS AND MEMORY CELLS
for white blood cells, refer to section 8.1
memory cells retain the information for the formation of pathogen specific antibodies.
11.3 HIV/AIDS
HIV is a virus that damages the immune system.
The immune system helps the body fight off infections.
Untreated HIV infects and kills CD4 cells, which are a type of immune cell called T
cells.
Over time, as HIV kills more CD4 cells, the body is more likely to get various types of
infections and cancers.
Without treatment, a person with HIV is likely to develop a serious condition called
AIDS.
At that point, the immune system is too weak to fight off other diseases and
infections.
With antiretroviral therapy, HIV can be well-controlled and life expectancy can be
nearly the same as someone who has not contracted HIV.
AIDS
AIDS is a condition that can develop in people with HIV, it’s the most advanced stage
of HIV.
But just because a person has HIV doesn’t mean they’ll develop AIDS.
HIV TRANSMISSION
CAUSES OF HIV
Scientists suspect the simian immunodeficiency virus (SIV) jumped from chimps to
humans when people consumed infected chimpanzee meat.
Once inside the human population, the virus mutated into what we now know as HIV.
Several different tests can be used to diagnose HIV. Healthcare providers determine
which test is best for each person.
1. ANTIBODY/ANTIGEN TESTS
Antibody/antigen tests are the most commonly used tests.
They can show positive results typically within 18-45days after someone
initially contracts HIV.
These tests check the blood for antibodies.
An antibody is a type of protein the body makes to fight an infection.
An antigen, on the other hand, is the part of the virus that activates the
immune system.
2. ANTIBODY TESTS
these tests check the blood solely for antibodies.
Between 23-90days after transmission, most people will develop detectable
HIV antibodies, which can be found in the blood or saliva.
These tests are done using blood tests or mouth swabs, and there’s no
preparation necessary.
Some tests provide results in 30 minutes or less and can be performed in a
healthcare provider’s office or clinic.
3. NUCLEIC ACID TEST (NAT)
This expensive test isn’t used for general screening. It’s for people who
have early symptoms of HIV or have a known risk factor.
This test doesn’t look for antibodies; it looks for the virus itself. It takes
from 5 to 21 days for HIV to be detectable in the blood.
This test is usually accompanied or confirmed by an antibody test.
If a person takes an HIV test during the window period, it’s likely they’ll receive a
negative result.
However, they can still transmit the virus to others during this time.
Someone who tests negative during the window might benefit from post-exposure
prophylaxis (PEP).
This is medication taken after an exposure to prevent getting HIV.
PEP needs to be taken as soon as possible after the exposure; it should be taken no
later than 72 hours after exposure, but ideally before then.
Another way to prevent getting HIV is pre-exposure prophylaxis (PrEP).
A combination of HIV drugs taken before potential exposure to HIV, PrEP can lower
the risk of contracting or spreading HIV when taken consistently.
The first few weeks after someone contracts HIV is called the acute infection stage.
During this time, the virus reproduces rapidly. The person’s immune system responds
by producing HIV antibodies. These are proteins that fight infection.
During this stage, some people have no symptoms at first. However, many people
experience symptoms in the first month or two after contracting the virus, but often
don’t realize they’re caused by HIV.
This is because symptoms of the acute stage can be very similar to those of the flu or
other seasonal viruses. They may be mild to severe, they may come and go, and they
may last anywhere from a few days to several weeks.
Fever
Chills
swollen lymph nodes
general aches and pains
skin rash
sore throat
headache
nausea
upset stomach
Because these symptoms are similar to common illnesses like the flu, the person with
them might not think they need to see a healthcare provider. And even if they do, their
healthcare provider might suspect the flu or mononucleosis and might not even
consider HIV.
Whether a person has symptoms or not, during this period their viral load is very high.
The viral load is the amount of HIV found in the bloodstream. A high viral load
means that HIV can be easily transmitted to someone else during this time.
Initial HIV symptoms usually resolve within a few months as the person enters the
chronic, or clinical latency, stage of HIV. This stage can last many years or even
decades with treatment.
After the first month or so, HIV enters the clinical latency stage. This stage can last
from a few years to a few decades.
Some people don’t have any symptoms during this time, while others may have
minimal or nonspecific symptoms.
A nonspecific symptom is a symptom that doesn’t pertain to one specific disease or
condition.
These nonspecific symptoms may include:
1. headaches and other aches and pains
2. swollen lymph nodes
3. recurrent fevers
4. night sweats
5. fatigue
6. nausea
7. vomiting
8. diarrhea
9. weight loss
10. skin rashes
11. recurrent oral or vaginal yeast infections
12. pneumonia
13. shingles
HIV makes someone more susceptible to skin problems because the virus destroys
immune system cells that fight infection. Co-infections that can cause rash include:
1. molluscum contagiosum
2. herpes simplex
3. shingles
In addition, women with HIV are at increased risk of:
1. recurrent vaginal yeast infections
2. other vaginal infections, including bacterial vaginosis
3. pelvic inflammatory disease (PID)
4. menstrual cycle changes
5. human papillomavirus (HPV), which can cause genital warts and lead to cervical
cancer
While not related to HIV symptoms, another risk for women with HIV is that the
virus can be transmitted to a baby during pregnancy.
However, antiretroviral therapy is considered safe during pregnancy.
Women who are treated with antiretroviral therapy are at very low risk of passing
HIV to their baby during pregnancy and delivery.
Breastfeeding is also affected in women with HIV.
PREVENTION OF HIV
Safer sex and abstinence
Get tested for HIV. It’s important they learn their status and that of their partner.
Get tested for other sexually transmitted infections (STIs). If they test positive for
one, they should get it treated, because having an STI increases the risk of contracting
HIV.
Use condoms. They should learn the correct way to use condoms and use them every
time they have sex, whether it’s through vaginal or anal intercourse. It’s important to
keep in mind that pre-seminal fluids (which come out before male ejaculation) can
contain HIV.
Limit their sexual partners. They should have one sexual partner with whom they
have an exclusive sexual relationship.
Take their medications as directed if they have HIV. This lowers the risk of
transmitting the virus to their sexual partner.