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Drug Study MI

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DRU DO CLASSIFICATION ACTION INDICATION CONTRAINDIC NURSING

G SA ATION CONSIDERATIO
GE N
Generi Selective beta-blocking Selective  Use to  Hypersensitiv  Taper drug
c agents activity at the manage ity to drug gradually over
name: β1 receptor hypertensi  Patient with 2 wk with
Thera produces on sinus monitoring.
bloc cardioselecti  Use to bradycardia  Avoid driving
vity due to manage  Patient with or dangerous
Brand the higher myocardia cardiogenic activities if
Name: population of l infraction shock dizziness or
this receptor  Manageme weakness
in cardiac nt of occurs
tissue angina
pectoris
associated
with
coronary
atheroscler
osis.
Generi 6tab antineoplastics (cancer Methotrexate   Methotrex  Monitor result
c s medicines). calms your ate is used  Bad infection of CBC and
Name: Rou immune to treat liver function
 Dehydration
Metho te: system, to leukemia test
trexate help stop it and certain  Condition  Assess patient
Fre attacking types of resulting from for bleeding
Brand que your body's cancer of a defective and infection
Name: ncy: cells. This the breast, immune  Increase fluid
Otrexu Eve helps reduce skin, head system intake after
p ry the and neck, taking
Mo inflammation lung, or  Low blood methotrexate.
nda that causes uterus. counts due to
y swollen and bone marrow
stiff joints in  Methotrex failure
rheumatoid ate is also
arthritis, used to  Anemia
thickened treat
skin in severe  Decreased
psoriasis or psoriasis blood platelets
damage to and
 Low levels of
your bowel rheumatoi
white blood
in Crohn's d arthritis
cells
disease. in adults
 Low levels of
a type of white
blood cell
called
neutrophils

 Alcoholism

 Escape of fluid
into the lungs
2mg Biguanides Metformin  Solosamet  Hypersensitiv • Do not use with
Generi / decreases (Glimepiri ity to any renal dysfunction,
c 500 blood de) is a component of metabolic acidosis
Name:  mg glucose sulfonylur Solosamet • May cause
Glime 1 levels by ea SR, diarrhea, nausea,
piride tab decreasing indicated sulfonylureas, vomiting, lactic
+ hepatic as an sulfonamides acidosis
Metfor Rou glucose adjunct to or biguanides. • Monitor patient
min te: production diet and  IDDM (type 1 closely for
HCl (also called exercise to DM) ketoacidosis and
Fre gluconeogen improve  Diabeticketoa lactic acidosis,
Brand que esis), glycemic cidosis discontinue
Name: ncy: decreasing control in  Acute or medication
Solosa OD the intestinal adults with chronic immediately
met absorption of type 2 metabolic if acidotic
SR glucose, and diabetes acidosis. • May cause
increasing mellitu  Lactic metallic taste
insulin acidosis • Instruct patient
sensitivity by  Hypoxemia, that medication
increasing  Dehydration does not cure
peripheral diabetes
glucose GI
uptake and disturbances
utilization.
Generi 80m HMG-CoA reductase Catalyzes the  Treatment  Hypersensitiv  Advice the
c g/ inhibitors conversion of of several ity to patient not to
name: tab HMG-CoA types of atorvastatin crushed,
Atorva to dyslipidem  Active liver chewed or cut
statin Fre mevalonate, ias disease or prior to intake
que an early rate-  Used as a unexplained  Drug can be
Brand ncy: limiting step preventive transaminase taken without
Name: OD in cholesterol agent for elevation meals
biosynthesis myocardia  Women who  Advice pt. to
l infarction are pregnant avoid drinking
 Used as a or grapefruit juice
preventive breastfeeding and alcohol
agent for while taking
non-fatal atorvastatin
MI
Generi 40m Proton-pump inhibitors It stops  Treatment  contraindicate   take 30-60
c g gastric acid of d in patients minutes prior to
name: secretion by symptomat taking dosage eating
Omepr Rou selective ic forms  capsules should
azole te:I inhibition of gastroesop containing be swallowed
V the hageal rilpivirine whole
Brand ATPase enzy reflux  Hypersensitiv   instruct patient
Name: Fre me system. disease ity to this to report black
que In turn, it (GERD) drug tarry stool
ncy: suppresses  Use to
OD gastric basal treat
and heartburn
stimulates and gastric
acid secretion acid
hypersecre
tion
 promote
healing of
tissue
damage
and ulcers
caused by
gastric
acid and
H. pylori
infection

Generi 80m Analgesic and It works by  Use to  contraindicate  Instruct patients


c g antipyretic blocking a relieve d in the 3rd on symptoms of
name: 4tab certain pain, fever trimester of toxicity such as
Aspiri natural and pregnancy a ringing in the
n Rou substance in inflammati ears (tinnitus)
te: your body to on or hearing loss,
Brand Oral reduce pain  Reducing and unusual
Name: and swelling. the risk of bleeding or
Fre cardiovasc bruising
que ular death  Do not take
ncy: aspirin with
HS alcohol due to
OD an increased
risk of
bleeding.
 Administer
aspirin with
food or milk to
reduce the risk
of GI irritation
Generi 75m Antiplatelet drug clopidogrel  Used with  Hypersensitiv  Monitor for
c g/3 active form is aspirin to ity to signs of
name: tab a platelet treat clopidogrel bleeding
Clopid inhibitor that worsening  Don’t give on   Monitor CBC
ogrel 1tab irreversibly chest pain patient with and platelet
lunc binds to ADP  Used to bleeding count
Brand h receptors on keep blood condition  Discontinue use
Name: platelets. vessels  Avoid 5-7 days before
Fre This binding open and Alcoholic surgery
que prevents prevent beverages
ncy: ADP binding blood clots
OD to receptors, after
activation of certain
the procedures
glycoprotein (such as
complex, and cardiac
platelet stent).
aggregation  It blocks
platelets
from
sticking
together
and
prevents
them from
forming
harmful
clots.
Generi 1.5 Thrombolytic Agents converts  Use in the  contraindicate  contraindicated
c Unit plasminogen manageme d in patients with active
name: s+ to plasmin nt of acute with active bleeding,
Strept 90c which myocardia internal hypersensitivity
okinas c degrades l infarction bleeding ,
e D5 fibrin clots (AMI)  patients with bronchospasm,
W  For lysis severe intracranial
Brand of uncontrolled hemorrhage,
Name: intracoron hypertension, hypotension
ary intracranial  monitor closely
thrombi neoplasms, for bleeding
 improvem surgery within
ent of two months,
ventricular and recent
function stroke
 reduction
of
mortality
associated
with AMI
Generi 100 Corticosteroids Effects of  indicated  Hypersensitiv  Avoid in active
c mg corticosteroid for ity to untreated
name: s are infections hydrocortison infections
hydroc Rou decreased of the e  May cause
ortison te: vasodilation external  Untreated CNS alterations
e IV and auditory serious   Decrease
permeability canal infections wound healing
Brand Fre of capillaries,  Indicated (except  May elevate
Name: que as well as for certain tuberculous blood sugars
ncy: decreased endocrine, meningitis or  May increase
30m leukocyte rheumatic, septic shock) cholesterol and
ins migration to collagen, lipid values
sites of allergic,
inflammation ophthalmi
c,
respiratory
,
hematolog
ic,
neoplastic,
edematous
,
gastrointes
tinal
Generi 2mg Narcotic Analgesics Morphine  Used for  Known  Tell patient to
c binding to the hypersensitivi lie down during
name: opioid manageme ty to IV
Morph receptors nt of morphine administration.
ine blocks chronic,  Respiratory   Dilute and
transmission moderate depression in administer
Brand of to severe the absence of slowly IV
Name: nociceptive pain resuscitative  Do not take
signals, equipment leftover
signals pain-  Acute or medication for
modulating severe other disorders.
neurons in bronchial  Take this drug
the spinal asthma or exactly as
cord hypercarbia prescribed.
 Paralytic ileus Avoid alcohol,
antihistamines,
sedatives,
tranquilizers,
and over-the-
counter drugs.
 Report severe
nausea,
vomiting,
constipation,
shortness of
breath or
difficulty
breathing, rash.

Generi 1 analgesic and antipyretic Acetaminoph  Used for  Hypersensitiv  Do not self-
c amp drugs en increases the ity to medicate adults
name: the pain treatment paracetamol for pain
Parace threshold by of mild to  Do not give
tamol Rou inhibiting moderate children more
te: two isoforms pain and than 5 doses in
Brand IVc of reduction 24 h unless
Name: o cyclooxygen of fever prescribed by
ase, COX-1 physician
and COX-2,  Do not breast
which are feed while
involved in taking this drug
prostaglandin without
(PG) consulting
synthesis. physician

DRUG DOS CLASSIFI ACTION INDICATI CONTRAIND NURSING


AGE CATION S ONS ICATIONS CONSIDERATI
ON
Generic Amp Prokinetic Metoclopr Metoclopra  Gastrointes  Do not use
Name: ule agents amide mide is used tinal with GI
Metoclo causes to treat the bleeding obstruction
pramide Route antiemetic symptoms  Obstructio  May cause
: Oral effects by of slow n extrapyramida
Brand inhibiting stomach  Perforation l reaction,
Name: Frequ dopamine emptying  Pheochrom neurolyptic
Reglan ency: D2 and (gastropares ocytoma malignant
serotonin is) in  Seizures syndrome,
5-HT3 patients  Depression tardive
receptors with  Parkinson dyskinesia,
in the diabetes. It disease arrhythmias,
chemorec works by  History of blood pressure
eptor increasing tardive alterations,
trigger the dyskinesia hematologic
zone movements alterations,
(CTZ) or facial
located in contractions movements,
the area of the sedation
postrema stomach and  Can decrease
of the intestines. It effects of
brain. relieves levodopa
symptoms  Assess
such as nausea/vomiti
nausea, ng
vomiting,  Monitor liver
heartburn, a function tests
feeling of
fullness
after meals,
and loss of
appetite.
Insulin 8 Insulins The Insulin is  Administer
units primary indicated to  Low blood insulin
activity of improve sugar through
Route insulin is glycemic  Low appropriate
: the control in amount of route.
IV regulation adults and potassium  Check the
of glucose paediatric in the blood patency of the
Frequ metabolis patient with  liver IV
ency: m. Insulin diabetes problems  Monitor
promotes mellitus  Kidney glucose level
glucose disease
and amino  Monitor
acid potassium
uptake level
into  Monitor liver
muscle enzymes
and  Monitor
adipose kidney
tissues, function test
and other
tissues
except
brain and
liver. It
also has
an
anabolic
role in
stimulatin
g
glycogen,
fatty acid,
and
protein
synthesis.
Insulin
inhibits
gluconeog
enesis in
the liver

Generic 5mg/ Hyperpolari Ivabradin Ivabradine  Hypersensi  Monitor bp


name: tab zation- e is a pure is indicated tivity and cardiac
Ivabradi activated heart rate by the FDA rate
ne Route cyclic lowering to reduce  Decompen  Tell patients
: nucleotide- agent, the risk of sated heart to report
gated acting by hospitalizati failure significant
Frequ (HCN) selective on for signs and
Brand ency: channel bl and worsening  Blood symptoms
name: OD specific heart failure pressure such as
Coralan inhibition in adult less than dizziness,
of the patients 90/50 fatigue, or as
cardiac with stable, well as
pacemake symptomati symptoms of
r If current c chronic  Conductio atrial
that heart failure fibrillation
controls with left n such as
the ventricular abnormaliti palpitations or
spontaneo ejection es, e.g., shortness of
us fraction sick sinus breath.
diastolic ≤35%, who syndrome,  Instruct
depolarisa are in sinus sinoatrial patients to
tion in the rhythm with block, or take each dose
sinus resting heart third- with food.
node and rate ≥70 degree AV  Warn
regulates beats per block, patients to
heart rate minute. unless a avoid
pacemaker grapefruit
determines  Monitor
the heart liver
rate function
test.
 Severe
liver
impairment

 Patients
taking
cytochrom
e P450
3A4
(CYP3A4)
inhibitors

 Resting
heart rate
less than
60 before
therapy
initiation

Generic 0.6cc Low- Helps Enoxaparin  Active  Monitor for


name: Route molecular- keep your is indicated major signs of
Enoxapa : weight blood for the bleeding bleeding
rin SQ heaparin flowing prevention • Administer
Frequ smoothly of ischemic  History of in
Brand ency: by complicatio immune- subcutaneous
name: BID lowering ns in mediated tissue
Lovenox the unstable heparin- • DO NOT
activity of angina and induced eject air
clotting in non-Q- thrombocyt bubble prior to
proteins wave openia injection
in the myocardial (HIT) • DO NOT
blood infarction; it within the aspirate or
is indicated past 100 massage site.
in days or in
conjunction the  Avoid IM
with presence of injection
percutaneou circulating
s antibodies   Monitor
intervention [see Warni platelet count
and/or other ngs and closely if less
treatment Precaution than 100,000
for the s (5.4)] report to the
managemen  Known physician and
t of acute hypersensit stop ng
ST elevation ivity to medication.
myocardial enoxaparin
infarction.  sodium
(e.g.,
pruritus,
urticaria,
anaphylacti
c/anaphyla
ctoid
reactions) [
see Advers
e
Reactions
(6.2)]

 Known
hypersensit
ivity to
heparin or
pork
products

 Known
hypersensit
ivity to
benzyl
alcohol
(which is
in only the
multiple-
dose
formulatio
n of
Lovenox)

Generic 6u Insulins It is a For the  Administer


Name: Route short- treatment of  Low blood insulin
Humulin : acting patients sugar through
-R SQ insulin. It with  Low appropriate
works by diabetes amount of route.
Brand Frequ helping mellitus potassium  Daily rotate of
Name: ency: blood who require in the blood injection site
Insulin sugar insulin for  liver to prevent
NPH (glucose) the problems lipodystrophy.
get into maintenance  Kidney  Monitor
cells so of glucose disease glucose level
your body homeostasis
can use it .  Monitor
for potassium
energy. level
 Monitor liver
enzymes
 Monitor
kidney
function test
Generic 10mg sodium- helping Empaglifloz  History of • Monitor blood
Name: /tab glucose co- the body in is serious glucose level
Empaglif Route transporter 2 get rid of indicated as hypersensit •Monitor blood
lozi : (SGLT2) glucose an adjunct ivity pressure
inhibitors through to diet and reaction to • Monitor kidney
Brand Frequ the exercise to empagliflo function test
Name: ency: kidneys. improve zin or any • Assess for sign
Jardianc OD glycemic of the and symptoms of
e control in excipients dehydration, UTI
adult in and allergic
patients Jardiance  reaction after
with type 2 taking the
diabetes. It  Severe medication
is also renal
indicated to impairment
reduce the , end-stage
risk of renal
cardiovascul disease, or
ar death in dialysis
adult
 Hypotensio
patients
n
with both
 Dehydratio
type 2
n
diabetes
 Diabeticket
mellitus and
oacidosis
established
 Hypoglyce
cardiovascul
mia
ar disease
 UTI
Generic 1tab Stimulant Stimulatin Indicated to  Hypersensi • Monitor
Name: laxatives g enteric relieve tivity potassium level
Bisacody Route neurons to occasional  Obstructio • Not for use
l : cause constipation n or severe within 1 hour of
peristalsis and impaction taking milk
Brand Frequ ,  irregularity  Symptoms product
Name: ency: of appendi • Assess for
Dulcolax ODH citis or abdominal
S acute distention and
surgical bowel function
abdomen • Instruct patient to
 Dehydratio drink 1500-2000
n mL/day during
 Rectal therapy
bleeding • Monitor fluid and
 Hypocalem electrolyte levels
ia • Instruct patient to
take as ordered
Generic 40mg proton- Accumula Treatment  Hypersensi  Assess for
Name: /tab pump te in the and tivity to possible
Pantopra inhibitors acidic maintenance pantoprazo contraindicati
zole Route space of of erosive le or other ons and
: Oral the esophagitis, proton cautions:
Brand parietal treatment of pump history of
name: Frequ cell heartburn inhibitors allergy to a
ency: before associated  Therapy proton pump
OD being with GERD. increases inhibitor to
converted the risk reduce the risk
in of Salmone of
the canali lla, hypersensitivit
culi (smal Campyloba y reaction
l canal) of cter, and  Inspect and
the gastric other palpate the
parietal abdomen to
cell, an infections determine
acidic potential
environm underlying
ent, to medical
active sulf conditions;
onamide d assess for
erivatives changes in
bowel
elimination
and GI upset
to identify
possible
adverse
effects.

Generic 500m Uricosuric works by  Colchic  Hypersensi  Be alert for


Name: g/tab Agent decreasing ine tivity to the signs of
Colchici swelling capsule active kidney
ne Route and s are substance damage,
: Oral lessening indicate   Patients including
Brand the build- d for with severe bloody urine
name: Frequ up of uric prophyl renal (hematuria)
ency: acid axis of impairment and decreased
OD crystals gout  Colchicine or absent urine
that cause flares should not output. Report
pain in   Prophy be used in these signs to
then laxis of patients the physician
affected gout undergoing immediately.
joint(s).Th attack haemodial
is during ysis since  Monitor I&O
medicatio initiatio it cannot ratio and
n is also n of be pattern
used to therapy removed (during acute
prevent with by dialysis gouty attack):
attacks of allopuri or High fluid
pain in nol and exchange intake
the abdom uricosur transfusion promotes
en, chest, ic drugs . excretion and
or joints reduces
danger of
crystal
formation in
kidneys and
ureters.
 Monitor for
early signs of
colchicine
toxicity
including
weakness,
abdominal
discomfort,
anorexia,
nausea,
vomiting, and
diarrhea,
regardless of
administration
route. Report
to physician.
To avoid more
serious
toxicity, drug
should be
discontinued
promptly until
symptoms
subside.

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