NB Hyaline Membrane Disease
NB Hyaline Membrane Disease
NB Hyaline Membrane Disease
• Definition:
– A preterm neonate showing progressive respiratory
difficulty including tachypnea >60/mt, chest
retractions, grunting and cyanosis within 48-96
hours of life
– Chest radiograph shows uniform reticulogranular
pattern and peripheral air bronchogram
Incidence
2. Male sex
4. Perinatal asphyxia
5. Chorioamnionitis
6. Multiple gestation
8. Familial predisposition
Decreased risk
1. Chronic intrauterine distress
2. PROM
3. Maternal hypertension
4. IUGR/SGA
5. Corticosteroids
6. Thyroid hormone
7. Tocolytic agents (b2 agonist, NSAID etc)
Clinical presentation
1. Preterm delivary
1. Severe pneumonias
4. Pulmonary hemorrhage
5. Adult RDS
Other measures in RDS
• Antibiotics; Sedation
• Prognosis: depends on birth weight