CTCAE v5.0

MedDRA Code MedDRA SOC CTCAE Term Grade 1
Grade 2 Grade 3
10002272 Blood and lymphaAnemia Hemoglobin (Hgb)Hgb <10.0 - 8.0 g Hgb <8.0 g/dL; <4
10005329 Blood and lymphaBlood and lymphat Asymptomatic orModerate;
m minimal
Severe or medicall
10048580 Blood and lymphaBone marrow hypo Mildly hypocellulModerately hypoce Severely hypocell
10013442 Blood and lymphaDisseminated intr - Laboratory findinLaboratory findin
10014950 Blood and lymphaEosinophilia >ULN and >Baseli - Steroids initiated
10016288 Blood and lymphaFebrile neutropen- - ANC <1000/mm3 wit
10019491 Blood and lymphaHemolysis Laboratory evidenEvidence of hemoTransfusion or med
10019515 Blood and lymphaHemolytic uremi - - Laboratory finding
10024378 Blood and lymphaLeukocytosis - - >100,000/mm3
10025182 Blood and lymphaLymph node painMild pain Moderate pain; liSevere pain; limit
10027506 Blood and lymphaMethemoglobine - >ULN Requiring urgent
10043648 Blood and lymphaThrombotic thro - - Laboratory finding
10061589 Cardiac disordersAortic valve dise Asymptomatic valv Asymptomatic; mo Symptomatic; seve
10003586 Cardiac disordersAsystole Periods of asyst - -
10003658 Cardiac disordersAtrial fibrillation Asymptomatic, intNon-urgent medica Symptomatic, urge
10003662 Cardiac disordersAtrial flutter Asymptomatic, intNon-urgent medica Symptomatic, urge
10003673 Cardiac disordersAtrioventricular - Non-urgent intervSymptomatic and i
10003674 Cardiac disordersAtrioventricular bAsymptomatic, intNon-urgent interv-
10007515 Cardiac disordersCardiac arrest - - -
10007541 Cardiac disordersCardiac disordersAsymptomatic orModerate;
m minimal
Severe or medicall
10008481 Cardiac disordersChest pain - cardiMild pain Moderate pain; pa
Pain at rest; limi
10010276 Cardiac disordersConduction disorMild symptoms; in Non-urgent medica Symptomatic, urge
10011703 Cardiac disordersCyanosis - Present -
10019279 Cardiac disordersHeart failure Asymptomatic withSymptoms with mo Symptoms at rest
10069501 Cardiac disordersLeft ventricular s - - Symptomatic due t
10061532 Cardiac disordersMitral valve dise Asymptomatic valv Asymptomatic; mo Symptomatic; seve
10027786 Cardiac disordersMobitz (type) II aAsymptomatic, intSymptomatic; medi Symptomatic and i
10027787 Cardiac disordersMobitz type I Asymptomatic, intSymptomatic; medi Symptomatic and i
10028596 Cardiac disordersMyocardial infarc - Asymptomatic and Severe symptoms;
10028606 Cardiac disordersMyocarditis - Symptoms with mo Severe with sympt
10033557 Cardiac disordersPalpitations Mild symptoms; inIntervention indi -
10034040 Cardiac disordersParoxysmal atrialAsymptomatic, intNon-urgent medica Symptomatic, urge
10034474 Cardiac disordersPericardial effusi - Asymptomatic effEffusion with phy
10053565 Cardiac disordersPericardial tamp - - -
10034484 Cardiac disordersPericarditis Asymptomatic, ECGSymptomatic pericaPericarditis with
10061541 Cardiac disordersPulmonary valve Asymptomatic valv Asymptomatic; mo Symptomatic; seve
10038748 Cardiac disordersRestrictive card Imaging findings Symptomatic witho Symptomatic heart
10058597 Cardiac disordersRight ventricular Asymptomatic with Symptoms with mo Severe symptoms,
10040639 Cardiac disordersSick sinus syndr Asymptomatic, intSymptomatic, inteSymptomatic, inte
10040741 Cardiac disordersSinus bradycardiaAsymptomatic, intSymptomatic, inteSymptomatic, inte
10040752 Cardiac disordersSinus tachycardiaAsymptomatic, intSymptomatic; nonUrgent medical in
10042604 Cardiac disordersSupraventricular Asymptomatic, intNon-urgent medica Symptomatic, urge
10061389 Cardiac disordersTricuspid valve d Asymptomatic valv Asymptomatic; mo Symptomatic; seve
10047281 Cardiac disordersVentricular arrhy Asymptomatic, intNon-urgent medica Urgent interventi
10047290 Cardiac disordersVentricular fibrill - - -
10047302 Cardiac disordersVentricular tachy - Non-urgent medica Symptomatic, urge
10010331 Congenital, familiCongenital, familiAsymptomatic orModerate;
m minimalSevere or medicall
10013993 Ear and labyrinthEar and labyrinth Asymptomatic orModerate;
10014020 Ear and labyrinthEar pain Mild pain Moderate pain; liSevere pain; limit
10065785 Ear and labyrinthExternal ear pain Mild pain Moderate pain; liSevere pain; limit
10019245 Ear and labyrinthHearing impairedPediatric (on a 1, Pediatric
2, 3, 4, 6, (on
anda81,kHz
Pediatric
2, 3,
audiogram):
4, 6, (on
anda81,Threshold
kHz
2, 3,
audiogram):
4, 6,shift
and >20
8 Thresh
kHz
dBau
h
10065838 Ear and labyrinthMiddle ear infla Serous otitis Serous otitis, medMastoiditis; necro
10043882 Ear and labyrinthTinnitus Mild symptoms; inModerate symptom Severe symptoms;
10047340 Ear and labyrinthVertigo Mild symptoms Moderate symptom Severe symptoms;
10047386 Ear and labyrinthVestibular disord - Symptomatic; limSevere symptoms;
10001367 Endocrine disord Adrenal insuffici Asymptomatic; cliModerate symptom Severe symptoms;
10011655 Endocrine disord Cushingoid Mild symptoms; inModerate symptom Severe symptoms,
10012205 Endocrine disord Delayed puberty - No breast developNo breast develop
10014698 Endocrine disord Endocrine disordeAsymptomatic orModerate;
10018746 Endocrine disord Growth accelerat - >= +2 SD (standar -
10020705 Endocrine disord Hyperparathyroi Mild symptoms; in Moderate symptom -
10020850 Endocrine disord Hyperthyroidism Asymptomatic; cliSymptomatic; thyr Severe symptoms;
10021041 Endocrine disord HypoparathyroidAsymptomatic; cliModerate symptom Severe symptoms;
10062767 Endocrine disord Hypophysitis Asymptomatic orModerate;
10021067 Endocrine disord Hypopituitarism Asymptomatic orModerate;
10021114 Endocrine disord Hypothyroidism Asymptomatic; cliSymptomatic; thyr Severe symptoms;
10058084 Endocrine disord Precocious puberPhysical signs of Physical signs an -
10067734 Endocrine disord Testosterone defiAsymptomatic; miReplacement ther-
10047488 Endocrine disord Virilization Mild symptoms; inModerate symptom -
10005886 Eye disorders Blurred vision Intervention not Symptomatic; mode Symptomatic with
10007739 Eye disorders Cataract Asymptomatic; cliSymptomatic; mode Symptomatic with
10048492 Eye disorders Corneal ulcer - - Corneal ulcer wit
10013774 Eye disorders Dry eye Asymptomatic; cliSymptomatic; mode Symptomatic with
10015829 Eye disorders Extraocular musclAsymptomatic; cliUnilateral paresi Bilateral paresis
10015919 Eye disorders Eye disorders - OtAsymptomatic orModerate;
m minimalSevere or medical
10015958 Eye disorders Eye pain Mild pain Moderate pain; liSevere pain; limit
10061145 Eye disorders Eyelid function d Asymptomatic; cliSymptomatic; nono Limiting self care
10016757 Eye disorders Flashing lights Symptomatic butLimiting instrumeLimiting self care
10016778 Eye disorders Floaters Symptomatic butLimiting instrumeLimiting self care
10018304 Eye disorders Glaucoma Less than 8 mmHgEIOPo which can beEIOP causing visua
10023332 Eye disorders Keratitis Asymptomatic; cliSymptomatic; mode Symptomatic with
10029404 Eye disorders Night blindness Symptomatic butSymptomatic; mode Symptomatic with
10061322 Eye disorders Optic nerve disorAsymptomatic; cliModerate decrease Marked decrease i
10033703 Eye disorders Papilledema Asymptomatic; noSymptomatic;
v modeSymptomatic with
10054541 Eye disorders Periorbital edem Soft or non-pittinIndurated or pitt Edema associated
10034960 Eye disorders Photophobia Symptomatic butLimiting instrumeLimiting self care
10038848 Eye disorders Retinal detachme - - Macular sparing
10038897 Eye disorders Retinal tear No retinal detac No retinal detac -
10038901 Eye disorders Retinal vascular d - Retinal vascular Retinal vascular
10038923 Eye disorders Retinopathy Asymptomatic; cliSymptomatic; mode Symptomatic with
10061510 Eye disorders Scleral disorder No change in visi Symptomatic; mode Symptomatic with
10046851 Eye disorders Uveitis Anterior uveitis wAnterior uveitis wAnterior uveitis w
10047516 Eye disorders Vision decreased - Moderate decrease Marked decrease i
10047656 Eye disorders Vitreous hemorr Intervention not Symptomatic; mode Symptomatic with
10047848 Eye disorders Watering eyes Intervention not Symptomatic; mode Marked decrease i
10000060 Gastrointestinal Abdominal distenAsymptomatic; cliSymptomatic; limSevere discomfort;
10000081 Gastrointestinal Abdominal pain Mild pain Moderate pain; liSevere pain; limit
10002153 Gastrointestinal Anal fissure Asymptomatic Symptomatic Invasive interven
10002156 Gastrointestinal Anal fistula Asymptomatic Symptomatic, inva Invasive interven
10055226 Gastrointestinal Anal hemorrhageMild symptoms; in Moderate symptom Transfusion indica
10065721 Gastrointestinal Anal mucositis Asymptomatic orSymptomatic; medi Severe symptoms;
10065722 Gastrointestinal Anal necrosis - - TPN or hospitaliza
10002167 Gastrointestinal Anal pain Mild pain Moderate pain; liSevere pain; limit
10002176 Gastrointestinal Anal stenosis Asymptomatic; cliSymptomatic; alteSymptomatic and s
10002180 Gastrointestinal Anal ulcer Asymptomatic; cliSymptomatic; alteSeverely altered G
10003445 Gastrointestinal Ascites Asymptomatic; cliSymptomatic; medi Severe symptoms;
10004222 Gastrointestinal Belching Increase from basIntervention init -
10005265 Gastrointestinal Bloating No change in bowe Symptomatic, decr-
10065747 Gastrointestinal Cecal hemorrhagMild symptoms; in Moderate symptom Transfusion indica
10008417 Gastrointestinal Cheilitis Asymptomatic; cliModerate symptom Severe symptoms;
10009167 Gastrointestinal Chylous ascites Asymptomatic; cliSymptomatic; medi Severe symptoms;
10009887 Gastrointestinal Colitis Asymptomatic; cliAbdominal pain; m Severe abdominal
10009995 Gastrointestinal Colonic fistula Asymptomatic Symptomatic, inva Invasive interven
10009998 Gastrointestinal Colonic hemorrh Mild symptoms; in Moderate symptom Transfusion indica
10010000 Gastrointestinal Colonic obstructi Asymptomatic; cliSymptomatic; alteHospitalization in
10010001 Gastrointestinal Colonic perforati - Invasive intervenInvasive interven
10010004 Gastrointestinal Colonic stenosis Asymptomatic; cliSymptomatic; alteSeverely altered G
10010006 Gastrointestinal Colonic ulcer Asymptomatic; cliSymptomatic; alteSeverely altered G
10010774 Gastrointestinal Constipation Occasional or int Persistent symptoObstipation with
10012318 Gastrointestinal Dental caries One or more denta Dental caries invoDental caries resu
10012727 Gastrointestinal Diarrhea Increase of <4 st Increase of 4 - 6 Increase of >=7 s
10013781 Gastrointestinal Dry mouth Symptomatic (e.g.,Moderate symptoms Inability to adeq
10013828 Gastrointestinal Duodenal fistula Asymptomatic Symptomatic, inva Invasive interven
10055242 Gastrointestinal Duodenal hemorrMild symptoms; in Moderate symptom Transfusion indica
10013830 Gastrointestinal Duodenal obstrucAsymptomatic; cliSymptomatic; alteHospitalization in
10013832 Gastrointestinal Duodenal perfora - Invasive intervenInvasive interven
10050094 Gastrointestinal Duodenal stenosiAsymptomatic; cliSymptomatic; alteSeverely altered G
10013836 Gastrointestinal Duodenal ulcer Asymptomatic; cliSymptomatic; medi Severely altered G
10013946 Gastrointestinal Dyspepsia Mild symptoms; in Moderate symptom Severe symptoms;
10013950 Gastrointestinal Dysphagia Symptomatic, able Symptomatic andSeverely altered
10014893 Gastrointestinal Enterocolitis Asymptomatic; cliAbdominal pain; m Severe or persiste
10062570 Gastrointestinal Enterovesical fistAsymptomatic Symptomatic, inva Invasive interven
10065851 Gastrointestinal Esophageal fistul Asymptomatic Symptomatic, inva Invasive interven
10015384 Gastrointestinal Esophageal hemoMild symptoms; in Moderate symptom Transfusion indica
10065727 Gastrointestinal Esophageal necro - - Inability to alime
10015387 Gastrointestinal Esophageal obstrAsymptomatic; cliSymptomatic; alteHospitalization in
10015388 Gastrointestinal Esophageal pain Mild pain Moderate pain; liSevere pain; limit
10055472 Gastrointestinal Esophageal perfo - Invasive intervenInvasive interven
10015448 Gastrointestinal Esophageal stenoAsymptomatic; cliSymptomatic; alteSeverely altered G
10015451 Gastrointestinal Esophageal ulcer Asymptomatic; cliSymptomatic; alteSeverely altered G
10015453 Gastrointestinal Esophageal varic - Self-limited; inte Transfusion indica
10015461 Gastrointestinal Esophagitis Asymptomatic; cliSymptomatic; alteSeverely altered
10016296 Gastrointestinal Fecal incontinencOccasional use ofDaily use of pads Severe symptoms;
10016766 Gastrointestinal Flatulence Mild symptoms; in Moderate; persist-
10065713 Gastrointestinal Gastric fistula Asymptomatic Symptomatic, inva Invasive interven
10017789 Gastrointestinal Gastric hemorrhaMild symptoms; in Moderate symptom Transfusion indica
10051886 Gastrointestinal Gastric necrosis - - Inability to alime
10017815 Gastrointestinal Gastric perforati - Invasive intervenInvasive interven
10061970 Gastrointestinal Gastric stenosis Asymptomatic; cliSymptomatic; alteSeverely altered G
10017822 Gastrointestinal Gastric ulcer Asymptomatic; cliSymptomatic; alteSeverely altered G
10017853 Gastrointestinal Gastritis Asymptomatic; cliSymptomatic; alteSeverely altered e
10066874 Gastrointestinal GastroesophagealMild symptoms; in Moderate symptom Severe symptoms;
10017947 Gastrointestinal Gastrointestinal dAsymptomatic orModerate;
10017877 Gastrointestinal Gastrointestinal fAsymptomatic Symptomatic, inva Invasive interven
10017999 Gastrointestinal Gastrointestinal Mild pain Moderate pain; liSevere pain; limit
10018043 Gastrointestinal Gastroparesis Mild nausea, earlyModerate symptoms Weight loss >=20%
10018286 Gastrointestinal Gingival pain Mild pain Moderate pain intSevere pain; inabi
10060640 Gastrointestinal Hemorrhoidal heMild symptoms; in Moderate symptom Transfusion indica
10019611 Gastrointestinal Hemorrhoids Asymptomatic; cliSymptomatic; band Severe symptoms;
10065728 Gastrointestinal Ileal fistula Asymptomatic Symptomatic, inva Invasive interven
10055287 Gastrointestinal Ileal hemorrhageMild symptoms; in Moderate symptom Transfusion indica
10065730 Gastrointestinal Ileal obstruction Asymptomatic; cliSymptomatic; alteHospitalization in
10021305 Gastrointestinal Ileal perforation - Invasive intervenInvasive interven
10021307 Gastrointestinal Ileal stenosis Asymptomatic; cliSymptomatic; alteSeverely altered G
10021309 Gastrointestinal Ileal ulcer Asymptomatic; cliSymptomatic; alteSeverely altered G
10021328 Gastrointestinal Ileus Asymptomatic and Symptomatic; alteSeverely altered
10055291 Gastrointestinal Intra-abdominal - Moderate symptom Transfusion indica
10065719 Gastrointestinal Jejunal fistula Asymptomatic Symptomatic, inva Invasive interven
10055300 Gastrointestinal Jejunal hemorrhaMild symptoms; in Moderate symptom Transfusion indica
10065732 Gastrointestinal Jejunal obstructi Asymptomatic; cliSymptomatic; alteHospitalization in
10023174 Gastrointestinal Jejunal perforati - Invasive intervenInvasive interven
10023176 Gastrointestinal Jejunal stenosis Asymptomatic; cliSymptomatic; alteSeverely altered G
10023177 Gastrointestinal Jejunal ulcer Asymptomatic; cliSymptomatic; alteSeverely altered G
10024561 Gastrointestinal Lip pain Mild pain Moderate pain; liSevere pain; limit
10051746 Gastrointestinal Lower gastrointe Mild symptoms; in Moderate symptom Transfusion indica
10025476 Gastrointestinal Malabsorption - Altered diet; oral Inability to alim
10028130 Gastrointestinal Mucositis oral Asymptomatic orModerate pain orSevere pain; inter
10028813 Gastrointestinal Nausea Loss of appetite wOral intake decreInadequate oral ca
10029957 Gastrointestinal Obstruction gastrAsymptomatic; cliSymptomatic; alteHospitalization in
10065720 Gastrointestinal Oral cavity fistulaAsymptomatic Symptomatic, inva Invasive interven
10054520 Gastrointestinal Oral dysesthesia Mild discomfort; nModerate pain; inDisabling pain; t
10030980 Gastrointestinal Oral hemorrhageMild symptoms; in Moderate symptom Transfusion indica
10031009 Gastrointestinal Oral pain Mild pain Moderate pain; liSevere pain; limit
10065703 Gastrointestinal Pancreatic duct sAsymptomatic; cliSymptomatic; alteSeverely altered G
10049192 Gastrointestinal Pancreatic fistulaAsymptomatic Symptomatic, inva Invasive interven
10033626 Gastrointestinal Pancreatic hemorMild symptoms; in Moderate symptom Transfusion indica
10058096 Gastrointestinal Pancreatic necros - - Tube feeding or T
10033645 Gastrointestinal Pancreatitis - Enzyme elevation;Severe pain; vomit
10034536 Gastrointestinal Periodontal diseaGingival recessionModerate gingivalSpontaneous bleed
10065704 Gastrointestinal Peritoneal necros - - Tube feeding or T
10036774 Gastrointestinal Proctitis Rectal discomfortSymptomatic (e.g.Severe symptoms;
10064993 Gastrointestinal Rectal fissure Asymptomatic Symptomatic Invasive interven
10038062 Gastrointestinal Rectal fistula Asymptomatic Symptomatic, inva Invasive interven
10038064 Gastrointestinal Rectal hemorrha Mild symptoms; in Moderate symptom Transfusion indica
10063190 Gastrointestinal Rectal mucositis Asymptomatic orSymptomatic; medi Severe symptoms;
10065709 Gastrointestinal Rectal necrosis - - Tube feeding or T
10065707 Gastrointestinal Rectal obstructio Asymptomatic; cliSymptomatic; alteHospitalization in
10038072 Gastrointestinal Rectal pain Mild pain Moderate pain; liSevere pain; limit
10038073 Gastrointestinal Rectal perforatio - Invasive intervenInvasive interven
10038079 Gastrointestinal Rectal stenosis Asymptomatic; cliSymptomatic; alteSeverely altered G
10038080 Gastrointestinal Rectal ulcer Asymptomatic; cliSymptomatic; alter Severely altered G
10038981 Gastrointestinal Retroperitoneal - Self-limited; inte Transfusion indica
10056681 Gastrointestinal Salivary duct inf Slightly thickenedThick, ropy, stick Acute salivary gla
10039411 Gastrointestinal Salivary gland fistAsymptomatic Symptomatic, inva Invasive interven
10065710 Gastrointestinal Small intestinal mAsymptomatic orSymptomatic; medi Severe pain; inter
10041101 Gastrointestinal Small intestinal oAsymptomatic; cliSymptomatic; alteHospitalization in
10041103 Gastrointestinal Small intestinal p - Invasive intervenInvasive interven
10062263 Gastrointestinal Small intestinal s Asymptomatic; cliSymptomatic; alteSymptomatic and s
10041133 Gastrointestinal Small intestine ulAsymptomatic; cliSymptomatic; alteSeverely altered G
10042112 Gastrointestinal Stomach pain Mild pain Moderate pain; liSevere pain; limit
10044030 Gastrointestinal Tooth developmen Asymptomatic; hyImpairment correc Maldevelopment wi
10044031 Gastrointestinal Tooth discolorati Surface stains - -
10044055 Gastrointestinal Toothache Mild pain Moderate pain; liSevere pain; limit
10045271 Gastrointestinal Typhlitis - - Symptomatic (e.g.
10055356 Gastrointestinal Upper gastrointeMild symptoms; in Moderate symptom Transfusion indica
10054692 Gastrointestinal Visceral arterial - Brief (<24 hrs) e Prolonged (>=24 h
10047700 Gastrointestinal Vomiting Intervention not Outpatient IV hydTube feeding, TPN
10008531 General disordersChills Mild sensation ofModerate tremorSevereo or prolong
10011912 General disordersDeath neonatal - - -
10011914 General disordersDeath NOS - - -
10061818 General disordersDisease progress - - -
10014222 General disordersEdema face Localized facial Moderate localizeSevere swelling; l
10050068 General disordersEdema limbs 5 - 10% inter-lim >10 - 30% inter-l >30% inter-limb d
10058720 General disordersEdema trunk Swelling or obscuReadily apparent Gross deviation f
10016059 General disordersFacial pain Mild pain Moderate pain; liSevere pain; limit
10016256 General disordersFatigue Fatigue relieved bFatigue not relievFatigue not reliev
10016558 General disordersFever 38.0 - 39.0 degre >39.0 - 40.0 degr >40.0 degrees C (
10016791 General disordersFlu like symptomMild flu-like sym Moderate symptom Severe symptoms;
10017577 General disordersGait disturbance Mild change in gaiModerate changeLimitingi self care
10018065 General disordersGeneral disordersAsymptomatic orModerate;
m minimal
Severe or medicall
10018112 General disordersGeneralized ede Noted on exam; 1Interfering with i Interferes with s
10021113 General disordersHypothermia - 35 - >32 degrees 32 - >28 degrees
10064774 General disordersInfusion site extr Painless edema Erythema with assUlceration or nec
10022095 General disordersInjection site rea Tenderness with oPain; lipodystrop Ulceration or nec
10062466 General disordersLocalized edema Localized to depeModerate localizeSevere localized
10025482 General disordersMalaise Uneasiness or lacUneasiness or lacUneasiness or lack
10028154 General disordersMulti-organ failu - - Shock with azotem
10054482 General disordersNeck edema Asymptomatic locModerate neck ede Generalized neck e
10062501 General disordersNon-cardiac chestMild pain Moderate pain; liSevere pain; limit
10033371 General disordersPain Mild pain Moderate pain; liSevere pain; limit
10042435 General disordersSudden death NO - - -
10069480 General disordersVaccination site Local lymph nodeLocalized ulcerat -
10051341 Hepatobiliary dis Bile duct stenosisAsymptomatic; cliSymptomatic; alteSeverely altered G
10004665 Hepatobiliary dis Biliary fistula - Symptomatic, inva Invasive interven
10006537 Hepatobiliary dis Budd-Chiari synd - Medical managem Severe or medicall
10008612 Hepatobiliary dis Cholecystitis - Symptomatic; medi Severe symptoms;
10017631 Hepatobiliary dis Gallbladder fistulAsymptomatic Symptomatic, inva Invasive interven
10059446 Hepatobiliary dis Gallbladder necro- - -
10017636 Hepatobiliary dis Gallbladder obstrAsymptomatic; cliSymptomatic; alteSymptomatic and s
10017638 Hepatobiliary dis Gallbladder pain Mild pain Moderate pain; liSevere pain; limit
10017639 Hepatobiliary dis Gallbladder perfo - - -
10019663 Hepatobiliary dis Hepatic failure - - Asterixis; mild en
10019678 Hepatobiliary dis Hepatic hemorrhMild symptoms; in Moderate symptom Transfusion indica
10019692 Hepatobiliary dis Hepatic necrosis - - -
10019705 Hepatobiliary dis Hepatic pain Mild pain Moderate pain; liSevere pain; limit
10019805 Hepatobiliary dis Hepatobiliary disoAsymptomatic orModerate;
m minimal
Severe or medicall
10034405 Hepatobiliary dis Perforation bile d - - Invasive interven
10036200 Hepatobiliary dis Portal hypertensi - Decreased portal Reversal/retrogra
10036206 Hepatobiliary dis Portal vein throm - Intervention not Medical intervent
10063675 Hepatobiliary dis Sinusoidal obstr - Blood bilirubin 2-Blood bilirubin >5
10001718 Immune system dAllergic reaction Systemic intervenOral interventionBronchospasm; hos
10002218 Immune system dAnaphylaxis - - Symptomatic bronc
10061664 Immune system dAutoimmune disoAsymptomatic; ser Evidence of autoiAutoimmune reacti
10052015 Immune system dCytokine release Fever with or witHypotension respHypotension mana
10021428 Immune system dImmune system dis Asymptomatic orModerate;
m minimal
Severe or medicall
10040400 Immune system dSerum sickness Asymptomatic; cliModerate arthralgi Severe arthralgia
10056519 Infections and infAbdominal infect - Oral intervention IV
i antibiotic, ant
10061640 Infections and infAnorectal infecti Localized, local i Oral intervention IV
i antibiotic, ant
10003011 Infections and infAppendicitis - - IV antibiotic, ant
10003012 Infections and infAppendicitis perf - - Medical intervent
10065744 Infections and infArteritis infective - - IV antibiotic, ant
10003999 Infections and infBacteremia - Blood culture pos -
10061695 Infections and infBiliary tract infec - Oral intervention IVi antibiotic, ant
10005047 Infections and infBladder infection - Oral intervention IVi antibiotic, ant
10061017 Infections and infBone infection - Oral intervention IVi antibiotic, ant
10006259 Infections and infBreast infection - Local infection wiIV antibiotic, anti
10055078 Infections and infBronchial infecti - Moderate symptoms; IV antibiotic, ant
10007810 Infections and infCatheter related - Localized; local inIV antibiotic, ant
10065761 Infections and infCecal infection - Localized; oral intIV antibiotic, ant
10008330 Infections and infCervicitis infectio - Localized; local inIV antibiotic, ant
10010741 Infections and infConjunctivitis Asymptomatic orSymptomatic; mode Symptomatic with
10010742 Infections and infConjunctivitis inf - Localized; local inIV antibiotic, ant
10061788 Infections and infCorneal infection - Localized; local inIV antibiotic, ant
10065765 Infections and infCranial nerve infe - - IV antibiotic, ant
10058666 Infections and infCytomegalovirus A i symptomatic orModerate
m symptom Severe or medicall
10064687 Infections and infDevice related in - Oral intervention IV antibiotic, ant
10065752 Infections and infDuodenal infecti - Moderate symptoms IV antibiotic, ant
10014594 Infections and infEncephalitis infec - - IV antibiotic, ant
10014621 Infections and infEncephalomyelitis- - IV antibiotic, ant
10014678 Infections and infEndocarditis infec- - IV antibiotic, ant
10014801 Infections and infEndophthalmitis - Local interventio Systemic interven
10058838 Infections and infEnterocolitis infe - Passage of >3 unfo IV antibiotic, ant
10015109 Infections and infEpstein-Barr virusAsymptomatic orModerate
10058804 Infections and infEsophageal infect - Local interventionIV antibiotic, ant
10015929 Infections and infEye infection - Localized; local inIV antibiotic, ant
10016936 Infections and infFolliculitis Covering <10% ofCovering 10-30% >o30% BSA; systemi
10017544 Infections and infFungemia - Moderate symptom Severe or medicall
10062632 Infections and infGallbladder infec - Oral intervention IVi antibiotic, ant
10018784 Infections and infGum infection Local therapy indModerate symptoms; IV antibiotic, ant
10056522 Infections and infHepatic infection - Moderate symptoms; IV antibiotic, ant
10058827 Infections and infHepatitis B reactiAsymptomatic orModerate
10019799 Infections and infHepatitis viral Asymptomatic, intModerate symptom Symptomatic liver
10080137 Infections and infHerpes simplex reAsymptomatic orModerate
10021881 Infections and infInfections and infAsymptomatic orModerate;
10021918 Infections and infInfective myositis - Localized; local inIV antibiotic, ant
10023216 Infections and infJoint infection - Localized; local i Arthroscopic inter
10023424 Infections and infKidney infection - Oral intervention IVi antibiotic, ant
10023874 Infections and infLaryngitis - Moderate symptoms; IV antibiotic, ant
10065755 Infections and infLip infection Localized, local i Oral intervention IVi antibiotic, ant
10061229 Infections and infLung infection - Moderate symptoms; IV antibiotic, ant
10050823 Infections and infLymph gland infe - Localized; oral intIV antibiotic, ant
10057483 Infections and infMediastinal infec - - IV antibiotic, ant
10027199 Infections and infMeningitis - - IV antibiotic, ant
10065764 Infections and infMucosal infectio Localized, local i Oral intervention IV i antibiotic, ant
10028524 Infections and infMyelitis Asymptomatic; mild Moderate weakness Severe weakness o
10061304 Infections and infNail infection Localized, local i Oral intervention IVi antibiotic, ant
10033072 Infections and infOtitis externa Localized, local i Oral intervention IV i antibiotic, ant
10033078 Infections and infOtitis media - Localized; oral intIV antibiotic, ant
10055005 Infections and infOvarian infection - Localized; oral intIV antibiotic, ant
10051741 Infections and infPancreas infectio - - IV antibiotic, ant
10069138 Infections and infPapulopustular r Papules and/or pPapules and/or puPapules and/or pu
10034016 Infections and infParonychia Nail fold edema oLocal interventionOperative interven
10058674 Infections and infPelvic infection - Moderate symptoms; IV antibiotic, ant
10061912 Infections and infPenile infection Localized, local i Oral intervention IV i antibiotic, ant
10051472 Infections and infPeriorbital infect - Localized; local inIV antibiotic, ant
10065766 Infections and infPeripheral nerve - Localized; local inIV antibiotic, ant
10057262 Infections and infPeritoneal infect - - IV antibiotic, ant
10034835 Infections and infPharyngitis - Oral intervention IVi antibiotic, ant
10056627 Infections and infPhlebitis infectiv Localized, local i Oral intervention IVi antibiotic, ant
10061351 Infections and infPleural infection - Oral intervention IVi antibiotic, ant
10050662 Infections and infProstate infectio - Moderate symptoms; IV antibiotic, ant
10037888 Infections and infRash pustular - Localized; local inIV antibiotic, ant
10059827 Infections and infRhinitis infective - Localized; local intervention
- indicated
10039413 Infections and infSalivary gland inf - Moderate symptoms; IV antibiotic, ant
10062156 Infections and infScrotal infection Localized, local i Oral intervention IV i antibiotic, ant
10040047 Infections and infSepsis - - Blood culture pos
10040555 Infections and infShingles Localized, local i Local infection w Severe or medicall
10040753 Infections and infSinusitis - Localized; oral intIV antibiotic, ant
10040872 Infections and infSkin infection Localized, local i Oral intervention IVi antibiotic, ant
10065771 Infections and infSmall intestine in - Moderate symptoms; IV antibiotic, ant
10062255 Infections and infSoft tissue infect - Localized; oral intIV antibiotic, ant
10062112 Infections and infSplenic infection - - IV antibiotic, ant
10064505 Infections and infStoma site infect Localized, local i Oral intervention IV i antibiotic, ant
10043649 Infections and infThrush Asymptomatic; l Oral intervention IV antifungal inte
10048762 Infections and infTooth infection - Localized; local inIV antibiotic, ant
10044302 Infections and infTracheitis - Moderate symptoms; IV antibiotic, ant
10046300 Infections and infUpper respiratory- Moderate symptoms; IV antibiotic, ant
10052298 Infections and infUrethral infectio - Localized; oral intIV antibiotic, ant
10046571 Infections and infUrinary tract infe - Localized; oral intIV antibiotic, ant
10062233 Infections and infUterine infection - Moderate symptoms; IV antibiotic, ant
10046914 Infections and infVaginal infection Localized, local i Oral intervention IV i antibiotic, ant
10054688 Infections and infViremia - Moderate symptom Severe or medicall
10065772 Infections and infVulval infection Localized, local i Oral intervention IV i antibiotic, ant
10048038 Infections and infWound infection Localized, local i Oral intervention IV i antibiotic, ant
10002544 Injury, poisoning Ankle fracture Mild; non-operatiLimiting instrumeLimiting self care
10002899 Injury, poisoning Aortic injury - Operative interveSevere symptoms;
10003162 Injury, poisoning Arterial injury Asymptomatic diag Symptomatic; repa Severe symptoms;
10050458 Injury, poisoning Biliary anastomotAsymptomatic diag Symptomatic; medi Severe symptoms;
10065802 Injury, poisoning Bladder anastomoAsymptomatic diag Symptomatic; medi Severe symptoms;
10006504 Injury, poisoning Bruising Localized or in a Generalized -
10006634 Injury, poisoning Burn Minimal symptoms Medical interven Moderate to majo
10061103 Injury, poisoning Dermatitis radiat Faint erythema oModerate to bris Moist desquamatio
10065961 Injury, poisoning Esophageal anastAsymptomatic diag Symptomatic; medi Severe symptoms;
10016173 Injury, poisoning Fall Minor with no resuSymptomatic; noni Hospitalization in
10065788 Injury, poisoning Fallopian tube anAsymptomatic; cliSymptomatic; medi Severe symptoms;
10065790 Injury, poisoning Fallopian tube pe - Invasive intervenInvasive interven
10017076 Injury, poisoning Fracture Asymptomatic; cliSymptomatic butSevere symptoms;
10065893 Injury, poisoning Gastric anastomotAsymptomatic diag Symptomatic; medi Severe symptoms;
10065879 Injury, poisoning Gastrointestinal Asymptomatic diag Symptomatic; medi Severe symptoms;
10065712 Injury, poisoning Gastrointestinal - Superficial necrosSevere symptoms;
10020100 Injury, poisoning Hip fracture - Hairline fracture Severe pain; hospi
10051792 Injury, poisoning Infusion related Mild transient reaTherapy or infusi Prolonged (e.g.,
10022161 Injury, poisoning Injury to carotid - Repair or revisionSevere symptoms; l
10022213 Injury, poisoning Injury to inferior Asymptomatic diag Symptomatic; repa Severe symptoms;
10065849 Injury, poisoning Injury to jugular - Repair or revisionSymptomatic limiti
10022356 Injury, poisoning Injury to superio Asymptomatic diag Symptomatic; repa Severe symptoms;
10022117 Injury, poisoning Injury, poisoning Asymptomatic orModerate;
10059095 Injury, poisoning Intestinal stoma Asymptomatic diag Symptomatic; medi Severe symptoms;
10059094 Injury, poisoning Intestinal stoma - Self-limited; inte Severe symptoms;
10049468 Injury, poisoning Intestinal stoma sMinimal bleedingModerate bleeding Transfusion indic
10065826 Injury, poisoning Intraoperative artPrimary repair of Partial resection Complete resectio
10065831 Injury, poisoning Intraoperative brePrimary repair of Partial resection Complete resectio
10065843 Injury, poisoning Intraoperative car- - Primary repair of
10065844 Injury, poisoning Intraoperative earPrimary repair of Partial resection Complete resectio
10065834 Injury, poisoning Intraoperative enPrimary repair of Partial resection Complete resectio
10065825 Injury, poisoning Intraoperative gasPrimary repair of Partial resection Complete resectio
10065842 Injury, poisoning Intraoperative hePrimary repair of Partial resection Complete resectio
10055298 Injury, poisoning Intraoperative h - - Postoperative inv
10065827 Injury, poisoning Intraoperative hep Primary repair of Partial resection Complete resectio
10065829 Injury, poisoning Intraoperative muPrimary repair of Partial resection Complete resectio
10065830 Injury, poisoning Intraoperative neu Primary repair of Partial resection Complete resectio
10065841 Injury, poisoning Intraoperative ocu Primary repair of Partial resection Complete resectio
10065845 Injury, poisoning Intraoperative renPrimary repair of Partial resection Complete resectio
10065840 Injury, poisoning Intraoperative repPrimary repair of Partial resection Complete resectio
10065832 Injury, poisoning Intraoperative resPrimary repair of Partial resection Complete resectio
10065847 Injury, poisoning Intraoperative spl- Primary repair of Resection or recon
10065828 Injury, poisoning Intraoperative uriPrimary repair of Partial resection Complete resectio
10065848 Injury, poisoning Intraoperative vePrimary repair of Partial resection Complete resectio
10065803 Injury, poisoning Kidney anastomotAsymptomatic diag Symptomatic; medi Severe symptoms;
10065891 Injury, poisoning Large intestinal Asymptomatic diag Symptomatic; medi Severe symptoms;
10050457 Injury, poisoning Pancreatic anastoAsymptomatic diag Symptomatic; medi Severe symptoms;
10065705 Injury, poisoning Pharyngeal anastAsymptomatic diag Symptomatic; medi Severe symptoms;
10055322 Injury, poisoning Postoperative h Mild symptoms; in Moderate bleeding Transfusion indica
10056745 Injury, poisoning Postoperative tho- Extubated within Extubated >72 hrs
10065745 Injury, poisoning Prolapse of intes Asymptomatic; reRecurrent after maSevere symptoms;
10065822 Injury, poisoning Prolapse of uros Asymptomatic; cliLocal care or mai Dysfunctional sto
10037767 Injury, poisoning Radiation recall Faint erythema oModerate to bris Moist desquamatio
10065894 Injury, poisoning Rectal anastomotiAsymptomatic diagSymptomatic; medi Severe symptoms;
10040102 Injury, poisoning Seroma Asymptomatic; cliSymptomatic; simpSymptomatic, elec
10065892 Injury, poisoning Small intestinal Asymptomatic diagSymptomatic; medi Severe symptoms;
10065897 Injury, poisoning Spermatic cord a Asymptomatic diagSymptomatic; medi Severe symptoms;
10041569 Injury, poisoning Spinal fracture Mild back pain; nModerate back pai Severe back pain;
10065898 Injury, poisoning Stenosis of gastr - Symptomatic; IV fSeverely altered G
10042127 Injury, poisoning Stomal ulcer Asymptomatic; cliSymptomatic; mediSevere symptoms;
10062548 Injury, poisoning Tracheal hemorr Mild symptoms; in Moderate symptom Transfusion indica
10044291 Injury, poisoning Tracheal obstructPartial asymptomaSymptomatic (e.g.,Stridor or respira
10065749 Injury, poisoning Tracheostomy sitMinimal bleedingModerate bleeding Transfusion indic
10065814 Injury, poisoning Ureteric anastomo Asymptomatic diag
Symptomatic; medi Severe symptoms;
10065815 Injury, poisoning Urethral anastomo Asymptomatic diag
10065882 Injury, poisoning Urostomy leak Asymptomatic diag Symptomatic; medi Severe symptoms;
10065883 Injury, poisoning Urostomy obstrucAsymptomatic; cliSymptomatic; dilaAltered organ func
10065748 Injury, poisoning Urostomy site bl Minimal bleedingModerate bleeding Transfusion indic
10065885 Injury, poisoning Urostomy stenosi - Symptomatic butSymptomatic
n (e.g.
10065886 Injury, poisoning Uterine anastomoAsymptomatic diag Symptomatic; medi Severe symptoms;
10046810 Injury, poisoning Uterine perforati - Invasive intervenInvasive interven
10046861 Injury, poisoning Vaccination compMild pain; erytheModerate pain; ErSevere pain; Eryt
10065887 Injury, poisoning Vaginal anastomot Asymptomatic diag
10065888 Injury, poisoning Vas deferens anaAsymptomatic diag Symptomatic; medi Severe symptoms;
10062169 Injury, poisoning Vascular access cTPA administratioDevice dislodgeme Pulmonary embolism
10047228 Injury, poisoning Venous injury Asymptomatic diag Symptomatic (e.g.,Severe symptoms;
10053692 Injury, poisoning Wound complicatObservation only;Bedside local car Operative interve
10048031 Injury, poisoning Wound dehiscencIncisional separatIncisional separatFascial disruptio
10048049 Injury, poisoning Wrist fracture Mild; non-operatiLimiting instrumeLimiting self care
10000636 Investigations Activated partial >ULN - 1.5 x ULN >1.5 - 2.5 x ULN >2.5 x ULN; bleed
10001551 Investigations Alanine aminotra>ULN - 3.0 x ULN >3.0 - 5.0 x ULN i >5.0 - 20.0 x ULN
10001675 Investigations Alkaline phospha>ULN - 2.5 x ULN >2.5 - 5.0 x ULN i >5.0 - 20.0 x ULN
10003481 Investigations Aspartate aminot>ULN - 3.0 x ULN >3.0 - 5.0 x ULN i >5.0 - 20.0 x ULN
10005332 Investigations Blood antidiuret Asymptomatic; cliSymptomatic; medi Hospitalization i
10005359 Investigations Blood bicarbonat<LLN and no inter - -
10005364 Investigations Blood bilirubin i >ULN - 1.5 x ULN >1.5 - 3.0 x ULN i >3.0 - 10.0 x ULN
10005452 Investigations Blood corticotro Asymptomatic; cliSymptomatic; medi Hospitalization i
10005561 Investigations Blood gonadotro Asymptomatic; cliSymptomatic; medi Severe symptoms;
10005630 Investigations Blood lactate de >ULN - -
10005778 Investigations Blood prolactin Asymptomatic; cliModerate symptom -
10065906 Investigations Carbon monoxide3 - 5 units below 6 - 8 units below Asymptomatic decr
10007612 Investigations Cardiac troponin Levels above the - Levels consistent
10007613 Investigations Cardiac troponin Levels above the - Levels consistent
10007839 Investigations CD4 lymphocytes<LLN - 500/mm3;<500 < - 200/mm3;<200
< - 50/mm3; <0
10008661 Investigations Cholesterol high >ULN - 300 mg/dL>300 - 400 mg/dL>400 - 500 mg/dL
10011268 Investigations CPK increased >ULN - 2.5 x ULN >2.5 x ULN - 5 x >5 x ULN - 10 x U
10011368 Investigations Creatinine increa>ULN - 1.5 x ULN >1.5 - 3.0 x basel >3.0 x baseline; >
10050528 Investigations Ejection fraction - Resting ejection Resting ejection
10014383 Investigations ElectrocardiogramAverage QTc 450Average
- 480 msQTc 481Average
- 500 msQTc >= 5
10050380 Investigations Electrocardiogra T wave flatteningNonspecific ST s -
10016596 Investigations Fibrinogen decre <1.0 - 0.75 x LLN <0.75 - 0.5 x LLN <0.5 - 0.25 x LLN
10016987 Investigations Forced expirator FEV1% (percentage FEV1 60 - 69% 50 - 59%
10056910 Investigations GGT increased >ULN - 2.5 x ULN >2.5 - 5.0 x ULN i >5.0 - 20.0 x ULN
10018748 Investigations Growth hormoneAsymptomatic; cliSymptomatic; medi -
10019150 Investigations Haptoglobin decr<LLN - -
10055599 Investigations Hemoglobin incr Increase in >0 - 2Increase in >2 - 4 Increase in >4 g/
10022402 Investigations INR increased >1.2 - 1.5; >1 - 1 >1.5 - 2.5; >1.5 - >2.5; >2.5 x basel
10022891 Investigations Investigations - OAsymptomatic orModerate;
m minimal
Severe or medicall
10024574 Investigations Lipase increased >ULN - 1.5 x ULN >1.5 - 2.0 x ULN; >2.0 - 5.0 x ULN
10025256 Investigations Lymphocyte coun<LLN - 800/mm3;<800 - 500/mm3;<500 < - 200/mm3; <
10025258 Investigations Lymphocyte count- >4000/mm3 - 20 >20,000/mm3
10029366 Investigations Neutrophil count<LLN - 1500/mm3; <1500 - 1000/mm3; <1000 - 500/mm3;
10062646 Investigations Pancreatic enzym<LLN and asymptIncrease in stool Sequelae of absor
10035528 Investigations Platelet count de<LLN - 75,000/mm3 <75,000 - 50,000/<50,000 - 25,000/
10040139 Investigations Serum amylase in>ULN - 1.5 x ULN >1.5 - 2.0 x ULN; >2.0 - 5.0 x ULN
10043770 Investigations Thyroid stimulat TSH increased and- -
10059895 Investigations Urine output dec - - Children: < 500 mL/1.73 m2 body surfac
10047580 Investigations Vital capacity ab 90 - 75% of predi<75 - 50% of pred<50% of predicted
10047896 Investigations Weight gain 5 - <10% from bas10 - <20% from b>=20% from basel
10047900 Investigations Weight loss 5 to <10% from ba10 - <20% from ba>=20% from baseli
10049182 Investigations White blood cell <LLN - 3000/mm3; <3000 - 2000/mm3; <2000 - 1000/mm3;
10000486 Metabolism and nu
Acidosis pH <normal, but - pH <7.3
Alcohol intoleran - Present Severe symptoms;
Alkalosis pH >normal, but - pH >7.5
Anorexia Loss of appetite wOral intake altereAssociated with si
Dehydration Increased oral fl IV fluids indicate Hospitalization i
Glucose intoleranAsymptomatic; cliSymptomatic; dietSevere symptoms;
Hypercalcemia Corrected serum Corrected serum Cc orrected serum c
Hyperglycemia Abnormal glucoseChange in daily management
Insulin therapy
from
in baseline for a diabetic
Hyperkalemia >ULN - 5.5 mmol/>5.5 - 6.0 mmol/L;>6.0 - 7.0 mmol/L
Hyperlipidemia Requiring diet ch Requiring pharmac Hospitalization; p
Hypermagnesemi>ULN - 3.0 mg/dL - >3.0 - 8.0 mg/dL;
Hypernatremia >ULN - 150 mmol>150 - 155 mmol/L >155 - 160 mmol/L
Hyperphosphate Laboratory findinNoninvasive interSevere or medicall
Hypertriglycerid 150 mg/dL - 300 >300 mg/dL - 500>500 mg/dL - 100
Hyperuricemia >ULN without phy- >ULN with physio
Hypoalbuminemi<LLN - 3 g/dL; <LL<3 - 2 g/dL; <30 - <2 g/dL; <20 g/L
Hypocalcemia Corrected serum Cc orrected serum Cc orrected serum c
Hypoglycemia <LLN - 55 mg/dL; <55 - 40 mg/dL; <<40 - 30 mg/dL; <
Hypokalemia <LLN - 3.0 mmol/Symptomatic with<3.0 - 2.5 mmol/L
10021028 Metabolism and nuHypomagnesemia<LLN - 1.2 mg/dL;<1.2 - 0.9 mg/dL; <0.9 - 0.7 mg/dL;
10021038 Metabolism and nuHyponatremia <LLN - 130 mmol/125-129 mmol/L 125-129 mmol/L s
10021059 Metabolism and nuHypophosphatemLaboratory findinOral replacementSevere or medicall
10065973 Metabolism and nuIron overload - Moderate symptom Severe symptoms;
10027433 Metabolism and nuMetabolism and nu Asymptomatic orModerate;
m minimal
Severe or medicall
10029883 Metabolism and nuObesity - BMI 25 - 29.9 kg BMI 30 - 39.9 kg
10045152 Metabolism and nuTumor lysis synd - - Present
10065775 Musculoskeletal aAbdominal soft ti - Local wound care;Operative debridem
10003239 Musculoskeletal aArthralgia Mild pain Moderate pain; liSevere pain; limit
10003246 Musculoskeletal aArthritis Mild pain with in Moderate pain ass Severe pain associ
10066480 Musculoskeletal aAvascular necrosiAsymptomatic; cliSymptomatic; limSevere symptoms;
10003988 Musculoskeletal aBack pain Mild pain Moderate pain; liSevere pain; limit
10006002 Musculoskeletal aBone pain Mild pain Moderate pain; liSevere pain; limit
10048677 Musculoskeletal aButtock pain Mild pain Moderate pain; liSevere pain; limit
10048831 Musculoskeletal aChest wall necros - Local wound care;Operative debridem
10008496 Musculoskeletal aChest wall pain Mild pain Moderate pain; liSevere pain; limit
10015688 Musculoskeletal aExostosis Asymptomatic; cliSymptomatic; limSevere symptoms;
10065799 Musculoskeletal aFibrosis deep conMild induration, aModerate induratio Severe induration;
10016750 Musculoskeletal aFlank pain Mild pain Moderate pain; liSevere pain; limit
10062572 Musculoskeletal aGeneralized muscSymptomatic; perc Symptomatic; evid Limiting self care
10018761 Musculoskeletal aGrowth suppress Reduction in growReduction in growReduction in grow
10065779 Musculoskeletal aHead soft tissue - Local wound care;Operative debridem
10023215 Musculoskeletal aJoint effusion Asymptomatic; cliSymptomatic; limSevere symptoms;
10048706 Musculoskeletal aJoint range of mo<=25% loss of ROM >25 - 50% decreas>50% decrease in
10065796 Musculoskeletal aJoint range of moMild restriction oRotation <60 degre Ankylosed/fused o
10065800 Musculoskeletal aJoint range of moStiffness; difficul Pain with range o<50% lumbar spine
10023509 Musculoskeletal aKyphosis Asymptomatic; cliModerate accentua Severe accentuati
10024842 Musculoskeletal aLordosis Asymptomatic; cliModerate accentua Severe accentuati
10028294 Musculoskeletal aMuscle cramp Mild pain Moderate pain; liSevere pain; limit
10065776 Musculoskeletal aMuscle weaknessSymptomatic; perc Symptomatic; evid Limiting self care
10028395 Musculoskeletal aMusculoskeletal aAsymptomatic orModerate;
m minimal
Severe or medicall
10065783 Musculoskeletal aMusculoskeletal Cosmetically and Deformity,
f hypoplSignificant defor
10028411 Musculoskeletal aMyalgia Mild pain Moderate pain; liSevere pain; limit
10028653 Musculoskeletal aMyositis Mild pain Moderate pain ass Pain associated w
10028836 Musculoskeletal aNeck pain Mild pain Moderate pain; liSevere pain; limit
10065781 Musculoskeletal aNeck soft tissue n - Local wound care;Operative debridem
10031264 Musculoskeletal aOsteonecrosis Asymptomatic; cliSymptomatic; medi Severe symptoms;
10064658 Musculoskeletal aOsteonecrosis of Asymptomatic; cliSymptomatic; medi Severe symptoms;
10031282 Musculoskeletal aOsteoporosis Pediatric: Radiologic
Pediatric:
evidence
LowofBMD
low
Pediatric:
BMD
(z-score
with
Limiting
<=z -2.0)
score
self
and
ofcare
<=
significant
-2.0
ADLandfract
no h
10033425 Musculoskeletal aPain in extremity Mild pain Moderate pain; liSevere pain; limit
10065793 Musculoskeletal aPelvic soft tissue - Local wound care;Operative debridem
10039020 Musculoskeletal aRhabdomyolysis Asymptomatic, intNon-urgent intervSymptomatic, urge
10039226 Musculoskeletal aRotator cuff injurAsymptomatic orModerate;
m minimal
Severe or medicall
10039722 Musculoskeletal aScoliosis <20 degrees; clin >20 - 45 degrees;>45 degrees; scap
10065777 Musculoskeletal aSoft tissue necros - Local wound care;Operative debridem
10065778 Musculoskeletal aSoft tissue necros - Local wound care;Operative debridem
10065798 Musculoskeletal aSuperficial soft ti Mild induration, aModerate induratio
Severe induration;
10044684 Musculoskeletal aTrismus Decreased ROM (rDecreased ROM req Decreased ROM wit
10065738 Musculoskeletal aUnequal limb lenMild length disc Moderate length Severe d length dis
10048293 Neoplasms benign,Leukemia seconda- - -
10028533 Neoplasms benign,Myelodysplastic - - -
10029104 Neoplasms benign,Neoplasms benign, Asymptomatic orModerate;
m minimal
Severe or medicall
10040907 Neoplasms benign,Skin papilloma Asymptomatic; intIntervention initi -
10049737 Neoplasms benign,Treatment relate - - Non life-threate
10055351 Neoplasms benign,Tumor hemorrhaMild symptoms; in Moderate symptom Transfusion indica
10045158 Neoplasms benign,Tumor pain Mild pain Moderate pain; liSevere pain; limit
10053662 Nervous system dAbducens nerve dAsymptomatic; cliModerate symptom Severe symptoms;
10060929 Nervous system dAccessory nerve dAsymptomatic; cliModerate symptom Severe symptoms;
10000521 Nervous system dAcoustic nerve d Asymptomatic; cliModerate symptom Severe symptoms;
10001540 Nervous system dAkathisia Mild restlessnessModerate restlessSevere restlessnes
10001949 Nervous system dAmnesia Mild; transient mModerate; short Severe; long term
10002653 Nervous system dAnosmia Present - -
10002953 Nervous system dAphonia - - Voicelessness; un
10003074 Nervous system dArachnoiditis Mild symptoms Moderate symptom Severe symptoms;
10003591 Nervous system dAtaxia Asymptomatic; cliModerate symptom Severe symptoms;
10065417 Nervous system dBrachial plexopatAsymptomatic; cliModerate symptom Severe symptoms;
10065784 Nervous system dCentral nervous sAsymptomatic; cliModerate symptom Severe symptoms;
10008164 Nervous system dCerebrospinal fluPost-craniotomy:Post-craniotomy:Severe symptoms;
10009845 Nervous system dCognitive disturb Mild cognitive di Moderate cognitivSevere cognitive
10010250 Nervous system dConcentration imMild inattention Moderate impairme Severe impairment
10012373 Nervous system dDepressed level oDecreased level oSedation; slow reDifficult to arous
10013573 Nervous system dDizziness Mild unsteadinesModerate unstead Severe unsteadine
10013887 Nervous system dDysarthria Mild slurred speeModerate impairme Severe impairment
10062872 Nervous system dDysesthesia Mild sensory alteModerate sensorySevere sensory alt
10013911 Nervous system dDysgeusia Altered taste but Altered taste with-
10013951 Nervous system dDysphasia Awareness of receModerate receptiv Severe receptive o
10014217 Nervous system dEdema cerebral - - New onset; worse
10014625 Nervous system dEncephalopathy Mild symptoms Moderate symptom Severe symptoms;
10015832 Nervous system dExtrapyramidal diMild involuntary Moderate involunSevere involuntary
10051272 Nervous system dFacial muscle we Asymptomatic; cliModerate symptom Severe symptoms;
10061457 Nervous system dFacial nerve diso Asymptomatic; cliModerate symptom Severe symptoms;
10061185 Nervous system dGlossopharyngealAsymptomatic; cliModerate symptom Severe symptoms;
10018767 Nervous system dGuillain-Barre s Mild symptoms Moderate symptom Severe symptoms;
10019211 Nervous system dHeadache Mild pain Moderate pain; liSevere pain; limit
10020508 Nervous system dHydrocephalus Asymptomatic; cliModerate symptom Severe symptoms o
10020765 Nervous system dHypersomnia Mild increased neModerate increasSevere increased
10061212 Nervous system dHypoglossal nerveAsymptomatic; cliModerate symptom Severe symptoms;
10022763 Nervous system dIntracranial hem Asymptomatic; cliModerate symptom Ventriculostomy, I
10023030 Nervous system dIschemia cerebroAsymptomatic; cliModerate sympt -
10024264 Nervous system dLethargy Mild symptoms; rModerate symptom -
10024382 Nervous system dLeukoencephalopAsymptomatic; sma Moderate symptoms Severe symptoms;
10027175 Nervous system dMemory impairmMild memory impModerate memory Severe memory imp
10027198 Nervous system dMeningismus Mild symptoms Moderate symptom Severe symptoms;
10028041 Nervous system dMovements involMild symptoms Moderate symptom Severe symptoms;
10065780 Nervous system dMuscle weaknessSymptomatic; perc Symptomatic; evid Limiting self care
10065794 Nervous system dMuscle weaknessSymptomatic; perc Symptomatic; evid Limiting self care
10028417 Nervous system dMyasthenia graviAsymptomatic orModerate;
m minimal
Severe or medicall
10029205 Nervous system dNervous system diAsymptomatic orModerate;
m minimal
Severe or medicall
10029223 Nervous system dNeuralgia Mild pain Moderate pain; liSevere pain; limit
10029864 Nervous system dNystagmus - Moderate symptom Severe symptoms;
10053661 Nervous system dOculomotor nerveAsymptomatic; cliModerate symptom Severe symptoms;
10056388 Nervous system dOlfactory nerve d - Moderate symptom Severe symptoms;
10033987 Nervous system dParesthesia Mild symptoms Moderate symptom Severe symptoms;
10034580 Nervous system dPeripheral motorAsymptomatic; cliModerate symptom Severe symptoms;
10034620 Nervous system dPeripheral senso Asymptomatic Moderate symptom Severe symptoms;
10056238 Nervous system dPhantom pain Mild pain Moderate pain; liSevere pain; limit
10036653 Nervous system dPresyncope - Present (e.g., nea -
10063636 Nervous system dPyramidal tract Asymptomatic; cliModerate symptom Severe symptoms;
10061928 Nervous system dRadiculitis Mild symptoms Moderate symptoms Severe symptoms;
10038130 Nervous system dRecurrent laryngeAsymptomatic; cliModerate sympt Severe symptoms;
10063761 Nervous system dReversible poste - Moderate symptom Severe symptoms;
10039906 Nervous system dSeizure Brief partial seiz Brief generalized New onset seizure
10041349 Nervous system dSomnolence Mild but more thaModerate sedation Obtundation or s
10041416 Nervous system dSpasticity Mild or slight inc Moderate increase Severe increase i
10041549 Nervous system dSpinal cord comp - - Severe symptoms;
10042244 Nervous system dStroke Incidental radiogrMild to moderateSevere neurologic
10042772 Nervous system dSyncope - - Fainting; orthosta
10043245 Nervous system dTendon reflex de Ankle reflex reduAnkle reflex abseAbsence of all ref
10044391 Nervous system dTransient ischemiMild neurologic dModerate neurolog -
10044565 Nervous system dTremor Mild symptoms Moderate symptom Severe symptoms;
10060890 Nervous system dTrigeminal nerve Asymptomatic; cliModerate symptom Severe symptoms;
10074765 Nervous system dTrochlear nerve dAsymptomatic; cliModerate symptom Severe symptoms;
10061403 Nervous system dVagus nerve diso Asymptomatic; cliModerate symptom Severe symptoms;
10047166 Nervous system dVasovagal reacti - - Present
10054746 Pregnancy, puerpFetal growth reta - <10% percentile o<5% percentile of
10072314 Pregnancy, puerpPregnancy loss - - -
10036585 Pregnancy, puerpPregnancy, puerpeAsymptomatic orModerate;
m minimal
Severe or medicall
10036595 Pregnancy, puerpPremature deliveDelivery of a live Delivery of a live Delivery of a live
10001497 Psychiatric disordAgitation Mild mood alteraModerate mood al Severe agitation;
10002652 Psychiatric disordAnorgasmia Inability to achie Inability to achie -
10002855 Psychiatric disordAnxiety Mild symptoms; in Moderate symptom Severe symptoms;
10010300 Psychiatric disordConfusion Mild disorientati Moderate disorien Severe disorientat
10057066 Psychiatric disordDelayed orgasm Delay in achievin Delay in achievin -
10012218 Psychiatric disordDelirium Mild acute confusModerate and acut Severe and acute
10012260 Psychiatric disordDelusions - Moderate delusi Severe delusional
10012378 Psychiatric disordDepression Mild depressive Moderate depressSevere depressive
10015533 Psychiatric disordEuphoria Mild mood elevatModerate mood eSevere mood elev
10019077 Psychiatric disordHallucinations Mild hallucinationModerate halluciSevere hallucinati
10022437 Psychiatric disordInsomnia Mild difficulty fa Moderate difficultSevere difficulty
10022998 Psychiatric disordIrritability Mild; easily consoModerate; limitinSevere abnormal o
10024419 Psychiatric disordLibido decreased Decrease in sexual Decrease in sexual-
10024421 Psychiatric disordLibido increased Present - -
10026749 Psychiatric disordMania Mild manic sympto Moderate manic sy Severe manic symp
10034719 Psychiatric disordPersonality chan Mild personality Moderate persona Severe personalit
10037175 Psychiatric disordPsychiatric disordAsymptomatic orModerate;
m minimal
Severe or medicall
10037234 Psychiatric disordPsychosis Mild psychotic s Moderate psychoti Severe psychotic
10038743 Psychiatric disordRestlessness Mild symptoms; in Moderate symptom Severe symptoms;
10042458 Psychiatric disordSuicidal ideation Increased thoughtSuicidal ideation Specific plan to
10042464 Psychiatric disordSuicide attempt - - Suicide attempt o
10069339 Renal and urinaryAcute kidney inju - - Hospitalization i
10063575 Renal and urinaryBladder perforati - Invasive intervenInvasive interven
10048994 Renal and urinaryBladder spasm Intervention not Antispasmodics i Hospitalization i
10064848 Renal and urinaryChronic kidney dieGFR (estimated G eGFR or CrCl 59 eGFR or CrCl 29
10063057 Renal and urinaryCystitis noninfectMicroscopic hemat Moderate hematuri Gross hematuria; t
10013990 Renal and urinaryDysuria Present - -
10068405 Renal and urinaryGlucosuria Present - -
10019450 Renal and urinaryHematuria Asymptomatic; cliSymptomatic; urinGross hematuria; t
10019489 Renal and urinaryHemoglobinuria Asymptomatic; cli- -
10029164 Renal and urinaryNephrotic syndr - - Not immediately li
10037032 Renal and urinaryProteinuria 1+ proteinuria; u Pediatric: Urine P/C
Pediatric:
(Protein/Creatinine)
Urine P/C (Protein/Creatinine
ratio 0.5 - 1.9
10038359 Renal and urinaryRenal and urinaryAsymptomatic orModerate;
m minimal
Severe or medicall
10038385 Renal and urinaryRenal calculi Asymptomatic orSymptomatic;
m oralHospitalization in
10038419 Renal and urinaryRenal colic Mild pain not int Moderate pain; liHospitalization in
10038463 Renal and urinaryRenal hemorrhagMild symptoms; in Analgesics and heTransfusion indica
10065368 Renal and urinaryUrinary fistula - Symptomatic, inva Invasive interven
10046539 Renal and urinaryUrinary frequenc Present Limiting instrum -
10046543 Renal and urinaryUrinary incontin Occasional (e.g., Spontaneous; pads Intervention indic
10046555 Renal and urinaryUrinary retentionUrinary, suprapubPlacement of urinElective invasive
10061574 Renal and urinaryUrinary tract obs Asymptomatic; cliSymptomatic butAlteredn organ fun
10062225 Renal and urinaryUrinary tract painMild pain Moderate pain; liSevere pain; limit
10046593 Renal and urinaryUrinary urgency Present Limiting instrum -
10046628 Renal and urinaryUrine discolorati Present - -
10001927 Reproductive sys Amenorrhea - Present -
10003883 Reproductive sys Azoospermia - Absence of sperm-
10006179 Reproductive sys Breast atrophy Minimal asymmetr Moderate asymme Asymmetry >1/3 o
10006298 Reproductive sys Breast pain Mild pain Moderate pain; liSevere pain; limit
10013934 Reproductive sys Dysmenorrhea Mild symptoms; in Moderate symptom Severe symptoms;
10013941 Reproductive sys Dyspareunia Mild discomfort oModerate discomfo Severe discomfort
10014326 Reproductive sys Ejaculation disor Diminished ejaculAnejaculation or -
10061461 Reproductive sys Erectile dysfunct Decrease in erectiDecrease in erectiDecrease in erect
10065789 Reproductive sys Fallopian tube obAsymptomatic; cliSymptomatic; elecSevere symptoms;
10054382 Reproductive sys Feminization acq Mild symptoms; in Moderate symptom -
10018146 Reproductive sys Genital edema Mild swelling or Readily apparent Lymphorrhea; gros
10018801 Reproductive sys Gynecomastia Asymptomatic Symptomatic (e.g.Severe symptoms;
10060602 Reproductive sys Hematosalpinx Minimal bleedingModerate bleeding Transfusion indic
10022992 Reproductive sys Irregular menstruIntermittent/irregular
Intermittent/irregular
menses for no- more
menses
than for
3 consecutive
more than 3menstrual
consecutiv
c
10061261 Reproductive sys Lactation disordeMild changes in laChanges in lactati -
10027313 Reproductive sys Menorrhagia Mild; iron supple Moderate symptom Severe; transfusi
10065823 Reproductive sys Nipple deformity Asymptomatic; asy Symptomatic; asym -
10030300 Reproductive sys Oligospermia Sperm concentrati- -
10065763 Reproductive sys Ovarian hemorrhMild symptoms; in Moderate symptom Transfusion indica
10033279 Reproductive sys Ovarian rupture Asymptomatic clin Symptomatic andTransfusion; inva
10033314 Reproductive sys Ovulation pain - Present -
10064026 Reproductive sys Pelvic floor musc Asymptomatic; cliSymptomatic, notSevere symptoms;
10034263 Reproductive sys Pelvic pain Mild pain Moderate pain; liSevere pain; limit
10034310 Reproductive sys Penile pain Mild pain Moderate pain; liSevere pain; limit
10061339 Reproductive sys Perineal pain Mild pain Moderate pain; liSevere pain; limit
10036601 Reproductive sys Premature meno - Present -
10055325 Reproductive sys Prostatic hemorr Mild symptoms; in Moderate symptom Transfusion indica
10055026 Reproductive sys Prostatic obstruc Asymptomatic; cliSymptomatic; elecSevere symptoms;
10036968 Reproductive sys Prostatic pain Mild pain Moderate pain; liSevere pain; limit
10038604 Reproductive sys Reproductive systAsymptomatic orModerate;
m minimal
Severe or medicall
10039757 Reproductive sys Scrotal pain Mild pain Moderate pain; liSevere pain; limit
10065762 Reproductive sys Spermatic cord Mild symptoms; in Moderate symptom Transfusion indica
10065805 Reproductive sys Spermatic cord obAsymptomatic; cliSymptomatic; elecSevere symptoms;
10043306 Reproductive sys Testicular disordeAsymptomatic; cliSymptomatic butSevere
n symptoms;
10055347 Reproductive sys Testicular hemor Mild symptoms; in Moderate symptom Transfusion indica
10043345 Reproductive sys Testicular pain Mild pain Moderate pain; liSevere pain; limit
10065811 Reproductive sys Uterine fistula Asymptomatic Symptomatic, inva Invasive interven
10046789 Reproductive sys Uterine hemorrh Mild symptoms; in Moderate symptom Transfusion indica
10065928 Reproductive sys Uterine obstructiAsymptomatic; cliSymptomatic; elecSevere symptoms;
10046809 Reproductive sys Uterine pain Mild pain Moderate pain; liSevere pain; limit
10046901 Reproductive sys Vaginal dischargeMild vaginal dischModerate to heavy -
10046904 Reproductive sys Vaginal dryness Mild vaginal drynModerate vaginalSevere vaginal dr
10065813 Reproductive sys Vaginal fistula Asymptomatic Symptomatic, inva Invasive interven
10046912 Reproductive sys Vaginal hemorrh Mild symptoms; in Moderate symptom Transfusion indica
10046916 Reproductive sys Vaginal inflammaMild discomfort oModerate discomfo Severe discomfort
10065817 Reproductive sys Vaginal obstructi Asymptomatic; cliSymptomatic; elecSevere symptoms;
10046937 Reproductive sys Vaginal pain Mild pain Moderate pain; liSevere pain; limit
10065818 Reproductive sys Vaginal perforati - Invasive intervenInvasive interven
10053496 Reproductive sys Vaginal stricture Asymptomatic; miVaginal narrowingVaginal narrowing
10001409 Respiratory, thor Adult respiratory - - Present with radio
10001723 Respiratory, thor Allergic rhinitis Mild symptoms; in Moderate symptom -
10002972 Respiratory, thor Apnea - - Present; medical
10003504 Respiratory, thor Aspiration Asymptomatic; cliAltered eating haDyspnea and pneum
10003598 Respiratory, thor Atelectasis Asymptomatic; cliSymptomatic (e.g.Supplemental oxyge
10006437 Respiratory, thor Bronchial fistula Asymptomatic Symptomatic, inva Invasive interven
10006440 Respiratory, thor Bronchial obstrucAsymptomatic; cliSymptomatic (e.g.Shortness of breat
10063524 Respiratory, thor Bronchial stricturAsymptomatic; cliSymptomatic (e.g.Shortness of breat
10053481 Respiratory, thor Bronchopleural fiAsymptomatic Symptomatic, inva Hospitalization; i
10065746 Respiratory, thor BronchopulmonarMild symptoms; in Moderate symptom Transfusion indica
10006482 Respiratory, thor Bronchospasm Mild symptoms; in Symptomatic; mediLimiting self car
10051228 Respiratory, thor Chylothorax Asymptomatic; cliSymptomatic; medi Severe symptoms;
10011224 Respiratory, thor Cough Mild symptoms; no Moderate symptomsSevere symptoms;
10013963 Respiratory, thor Dyspnea Shortness of bre Shortness of breaShortness of breat
10015090 Respiratory, thor Epistaxis Mild symptoms; in Moderate symptomsTransfusion; invas
10020039 Respiratory, thor Hiccups Mild symptoms; in Moderate symptomsSevere symptoms;
10020201 Respiratory, thor Hoarseness Mild or intermitt Moderate or persiSevere voice cha
10021143 Respiratory, thor Hypoxia - Decreased oxygenDecreased oxygen
10023838 Respiratory, thor Laryngeal edemaAsymptomatic; cliSymptomatic; medi Stridor; respirato
10065786 Respiratory, thor Laryngeal fistula Asymptomatic Symptomatic, inva Invasive interven
10065759 Respiratory, thor Laryngeal hemor Mild cough or traModerate symptom Transfusion indica
10065735 Respiratory, thor Laryngeal inflam Mild sore throat; Moderate sore thrSevere throat pai
10065880 Respiratory, thor Laryngeal mucositEndoscopic findinModerate pain, an Severe pain; seve
10059639 Respiratory, thor Laryngeal obstrucAsymptomatic; cliSymptomatic (e.g., Limiting self care
10023862 Respiratory, thor Laryngeal stenosiAsymptomatic; cliSymptomatic (e.g., Limiting self care
10062667 Respiratory, thor Laryngopharyngea Mild symptoms; no Moderate symptomsSevere symptoms;
10023891 Respiratory, thor Laryngospasm - Transient episodeRecurrent episode
10056356 Respiratory, thor Mediastinal hem Mild symptoms; in Moderate symptom Transfusion indica
10028735 Respiratory, thor Nasal congestion Mild symptoms; in Moderate symptom Associated with b
10068319 Respiratory, thor Oropharyngeal paMild pain Moderate pain; alt
Severe pain; sever
10034825 Respiratory, thor Pharyngeal fistul Asymptomatic Symptomatic, inva Invasive interven
10055315 Respiratory, thor Pharyngeal hemoMild symptoms; in Moderate symptom Transfusion indica
10065881 Respiratory, thor Pharyngeal mucosEndoscopic findinModerate pain, an Severe pain; unabl
10065706 Respiratory, thor Pharyngeal necro - - Inability to alime
10050028 Respiratory, thor Pharyngeal stenosAsymptomatic; cliSymptomatic (e.g., Limiting self care
10034844 Respiratory, thor PharyngolaryngeaMild pain Moderate pain; liSevere pain; limit
10035598 Respiratory, thor Pleural effusion Asymptomatic; cliSymptomatic; inteSymptomatic with
10055319 Respiratory, thor Pleural hemorrhaAsymptomatic; miSymptomatic or a>1000 ml of blood
10035623 Respiratory, thor Pleuritic pain Mild pain Moderate pain; liSevere pain; limit
10035742 Respiratory, thor Pneumonitis Asymptomatic; cliSymptomatic; medi Severe symptoms;
10035759 Respiratory, thor Pneumothorax Asymptomatic; cliSymptomatic; inteSclerosis and/or o
10036402 Respiratory, thor Postnasal drip Mild symptoms; in Moderate symptom -
10036790 Respiratory, thor Productive coughOccasional/minimModerate sputumPersistent or cop
10037375 Respiratory, thor Pulmonary edemRadiologic findin Moderate dyspnea Severe dyspnea or
10037383 Respiratory, thor Pulmonary fibrosiRadiologic pulmon Evidence of pulmoSevere hypoxia; e
10065873 Respiratory, thor Pulmonary fistulaAsymptomatic Symptomatic, inva Invasive interven
10037400 Respiratory, thor Pulmonary hyperMinimal dyspnea;Moderate dyspnea, Severe symptoms,
10038695 Respiratory, thor Respiratory failur - - -
10038738 Respiratory, thor Respiratory, thoraAsymptomatic orModerate;
m minimal
Severe or medicall
10038921 Respiratory, thor Retinoic acid sy Fluid retention; <Moderate signs oSevere symptoms;
10039100 Respiratory, thor Rhinorrhea Present - -
10062244 Respiratory, thor Sinus disorder Asymptomatic muc Symptomatic steno Stenosis with sign
10040747 Respiratory, thor Sinus pain Mild pain Moderate pain; liSevere pain; limit
10040975 Respiratory, thor Sleep apnea Snoring and noctuModerate apnea Oxygen
an desaturati
10041232 Respiratory, thor Sneezing Mild symptoms; in Moderate symptom -
10041367 Respiratory, thor Sore throat Mild pain Moderate pain; liSevere pain; limit
10042241 Respiratory, thor Stridor - - Respiratory distre
10065787 Respiratory, thor Tracheal fistula Asymptomatic Symptomatic, inva Invasive interven
10065900 Respiratory, thor Tracheal mucositiEndoscopic findinModerate symptoms Severe pain; hemo
10050816 Respiratory, thor Tracheal stenosisAsymptomatic; cliSymptomatic (e.g., Stridor or respira
10047681 Respiratory, thor Voice alteration Mild or intermitt Moderate or persiSevere voice chan
10047924 Respiratory, thor Wheezing Detectable airwaModerate symptoms Severe respirator
10001760 Skin and subcutanAlopecia Hair loss of <50% Hair loss of >=50%-
10005901 Skin and subcutanBody odor Mild odor; physiciPronounced odor;-
10006556 Skin and subcutanBullous dermatitiAsymptomatic; blBlisters covering Blisters covering
10013786 Skin and subcutanDry skin Covering <10% BSCovering 10 - 30%Covering >30% BSA
10014184 Skin and subcutanEczema Asymptomatic orModerate;
mild symptoms; additional
topicalSevere or medicall
medical intervention over bas
10015218 Skin and subcutanErythema multif Target lesions co Target lesions co Target lesions co
10015277 Skin and subcutanErythroderma - Erythema coverinErythema covering
10016241 Skin and subcutanFat atrophy Covering <10% B Covering 10 - 30%Covering >30% BSA
10055525 Skin and subcutanHair color changePresent - -
10019049 Skin and subcutanHair texture abn Present - -
10020112 Skin and subcutanHirsutism In women, increaseIn women, increas-
10020642 Skin and subcutanHyperhidrosis Limited to one sitInvolving >1 site Associated with
10020649 Skin and subcutanHyperkeratosis Present - Limiting self-care
10020864 Skin and subcutanHypertrichosis Increase in lengt Increase in lengt -
10021013 Skin and subcutanHypohidrosis - Symptomatic; limIncrease in body
10062315 Skin and subcutanLipohypertrophy Asymptomatic anCovering 10 - 30%Covering >30% BSA
10028689 Skin and subcutanNail changes Present - -
10028691 Skin and subcutanNail discolorationAsymptomatic; cli- -
10049281 Skin and subcutanNail loss Asymptomatic sepa Symptomatic separa -
10062283 Skin and subcutanNail ridging Asymptomatic; cli- -
10033474 Skin and subcutanPain of skin Mild pain Moderate pain; liSevere pain; limit
10054524 Skin and subcutanPalmar-plantar e Minimal skin chanSkin changes (e.g.Severe skin change
10034966 Skin and subcutanPhotosensitivity Painless erythemTender erythemaErythema covering
10037087 Skin and subcutanPruritus Mild or localized;Widespread and in Widespread and co
10037549 Skin and subcutanPurpura Combined area ofCombined area ofCombined area of
10037847 Skin and subcutanRash acneiform Papules and/or pPapules and/or puPapules and/or pu
10037868 Skin and subcutanRash maculo-papu Macules/papules Macules/papules
c Macules/papules
c
10049120 Skin and subcutanScalp pain Mild pain Moderate pain; liSevere pain; limit
10040785 Skin and subcutanSkin and subcutanAsymptomatic orModerate;
m minimal
Severe or medicall
10040799 Skin and subcutanSkin atrophy Covering <10% BSA Covering 10 - 30%Covering >30% BSA
10040865 Skin and subcutanSkin hyperpigmenHyperpigmentatioHyperpigmentatio-
10040868 Skin and subcutanSkin hypopigmentHypopigmentation Hypopigmentation-
10051837 Skin and subcutanSkin induration Mild induration, aModerate induratio Severe induration;
10040947 Skin and subcutanSkin ulceration Combined area ofCombined area ofCombined u area of
10042033 Skin and subcutanStevens-Johnson - - Skin sloughing c
10042344 Skin and subcutanSubcutaneous e Asymptomatic orModerate;
10043189 Skin and subcutanTelangiectasia Telangiectasias Telangiectasias c -
10044223 Skin and subcutanToxic epidermal n- - -
10046735 Skin and subcutanUrticaria Urticarial lesions Urticarial lesions Urticarial lesion
10041244 Social circumstanSocial circumstanAsymptomatic orModerate;
10042613 Surgical and mediSurgical and mediAsymptomatic orModerate;
10073529 Vascular disorderArterial thrombo - - Urgent interventi
10007196 Vascular disorderCapillary leak sy Asymptomatic Symptomatic; medi Severe symptoms;
10016825 Vascular disorderFlushing Asymptomatic; cliModerate symptom Symptomatic, asso
10019428 Vascular disorderHematoma Mild symptoms; in Minimally invasivTransfusion; inva
10020407 Vascular disorderHot flashes Mild symptoms; in Moderate symptom Severe symptoms;
10020772 Vascular disorderHypertension Adolescent: BP ≥120/80
Adolescent:
even Systolic
if < 95th
Pediatric
between
percentile
and130-139
adolescent:
or diastolic betwe
10021097 Vascular disorderHypotension Asymptomatic, intNon-urgent medica Medical intervent
10065773 Vascular disorderLymph leakage - Symptomatic; medi Severe symptoms;
10025233 Vascular disorderLymphedema Trace thickening oMarked discoloratSevere symptoms;
10048642 Vascular disorderLymphocele Asymptomatic; cliSymptomatic; medi Severe symptoms;
10034578 Vascular disorderPeripheral ischem- Brief (<24 hrs) e Prolonged (>=24 h
10034879 Vascular disorderPhlebitis - Present -
10042554 Vascular disorderSuperficial throm - Present -
10042569 Vascular disorderSuperior vena ca Asymptomatic; inc Symptomatic; medi Severe symptoms;
10043565 Vascular disorderThromboembolic Medical interventiMedical interventUrgent medical in
10047065 Vascular disorderVascular disordersAsymptomatic orModerate;
10047115 Vascular disorderVasculitis Asymptomatic, intModerate symptom Severe symptoms,
Grade 4 Grade 5 Definition Navigational NotCTCAE v5.0 Change
Life-threatening Death A disorder characterized by a reduClarification: Definition
Life-threatening Death - Clarification: Grade 3
Aplastic persiste Death A disorder characterized by the inability of the bone marrow to produce hematopoietic elem
Life-threatening Death A disorder characterized by systemic pathological activation of blood clotting mechanisms w
- - A disorder characterized by laboratAddition: Term
Life-threatening Death A disorder characterized by an ANC <1000/mm3 and a single temperature of >38.3 degrees
Life-threatening Death A disorder characterized by laboraClarification: Grade 2
Life-threatening Death A disorder characterized by a for Deletion: Grade 1
Clinical manifestaDeath A disorder characterized by laboratory test results that indicate an increased number of wh
- - A disorder characterized by a sensation of marked discomfort in a lymph node.
Life-threatening Death A disorder characterized by laboraAddition: Term
Life-threatening Death A disorder characterized by the pr Deletion: Grade 1
Life-threatening Death A disorder characterized by a defect in aortic valve function or structure.
Life-threatening Death A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this i
Life-threatening consequences;
Death embolus requiring
A disorder urgent intervention
characterized by a dysr Clarification: Grade 3, 4
Death embolus requiring
A disorder urgent intervention
characterized by a dysr Clarification: Grade 3, 4
Life-threatening Death A disorder characterized by a dysrhClarification: Grade 3
- - A disorder characterized by a dysrhythmia with a delay in the time required for the conducti
Life-threatening Death A disorder characterized by cessation of the pumping function of the heart.
- - A disorder charac Also consider CarAddition: Navigational note; Clarification: Grade 2, 3, Defi
Life-threatening Death A disorder characterized by patholo Clarification: Grade 2, 3, 4
- - A disorder characterized by a blui Addition: Term
Life-threatening Death A disorder charactIf left sided use Addition: Navigational note; Clarification: Grade 2, 3
Refractory or poorDeath A disorder charactAlso consider InveAddition: Navigational note; Clarification: Definition
Life-threatening Death A disorder characterized by a defect in mitral valve function or structure.
Life-threatening Death A disorder characterized by a dysrhy Clarification: Grade 3
Life-threatening Death A disorder characterized by a dysrhythmia with a progressively lengthening PR interval prior
Life-threatening Death A disorder characterized by gross necrosis of the myocardium; this is due to an interruption
Life-threatening Death A disorder characterized by inflamClarification: Grade 2, 3; Deletion: Grade 1
- - A disorder characterized by an unpleasant sensation of irregular and/or forceful beating of t
Life-threatening Death A disorder characterized by a dysr Clarification: Grade 2, 3
Life-threatening Death A disorder characterized by fluid collection within the pericardial sac, usually due to inflamm
Life-threatening Death A disorder characterized by an increase in intrapericardial pressure due to the collection of
Life-threatening Death A disorder characterized by irritation to the layers of the pericardium (the protective sac aro
Life-threatening Death A disorder characterized by a defect in pulmonary valve function or structure.
Refractory heart Death A disorder characterized by an inabi Addition: Grade 1, 2; Clarification: Grade 3
Life-threatening cDeath A disorder characterized by impairm Clarification: Grade 2, 3
Life-threatening Death A disorder characterized by a dysrhClarification: Grade 2, 3
- - A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per min
Life-threatening Death A disorder characterized by a defect in tricuspid valve function or structure.
Life-threatenin Death A disorder characterized by a dysrhClarification: Grade 3, 4
Life-threatenin Death A disorder characterized by a dysr Clarification: Grade 4
Life-threatenin Death A disorder characterized by a dysrhClarification: Grade 3, 4
- - A disorder characterized by a sensation of marked discomfort in the ear.
- - A disorder characterized by a sensation of marked discomfort in the external ear region.
Pediatric: Audiologic
- indication forAcochlear
disorderimplant;
characterized
> 40 dBbyHL
partialClarification:
(i.e., 45 dB HL or more);
Grade SNHL
1, 2, 3,at42 kHz and above
Life-threatening Death A disorder characterized by inflammation (physiologic response to irritation), swelling and r
- - A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking.
- - A disorder characterized by a sensation as if the external world were revolving around the p
- - A disorder characterized by dizziness, imbalance, nausea, and vision problems.
Life-threatening Death A disorder characterized by the adClarification: Definition
- - A disorder characterized by signs and symptoms that resemble Cushing's disease or syndrom
- - A disorder characterized by unusually late sexual maturity.
- - A disorder characterized by greater growth than expected for age.
- - A disorder characterized by an increase in production of parathyroid hormone by the parath
Life-threatening Death A disorder characterized by excessive levels of thyroid hormone in the body. Common caus
Life-threatening Death A disorder characterized by a decrease in production of parathyroid hormone by the parath
Life-threatening Death A disorder characterized by inflamma Addition: Term
Life-threatening Death A disorder characterized by a decr Addition: Term
Life-threatening Death A disorder characterized by a decrease in production of thyroid hormone by the thyroid gla
- - A disorder characterized by unusually early development of secondary sexual features; the
- - A disorder characterized by low te Addition: Term
- - A disorder characterized by inappropriate masculinization occurring in a female or prepube
Best corrected vi - A disorder characterized by visual Addition: Grade 4; Clarification: Grade 2, 3
Best corrected vi - A disorder characterized by partialClarification: Grade 2, 3, 4
Perforation in th - A disorder characterized by an areaClarification: Grade 3, 4; Deletion: Grade 2
- - A disorder characIf corneal ulcer i Addition: Navigational note; Clarification: Grade 1, 2, 3
Bilateral paresis - A disorder characterized by incompAddition: Grade 4; Clarification: Grade 2, 3
Sight-threatening - - Clarification: Grade 1, 2, 3, 4
- - A disorder characterized by a sensation of marked discomfort in the eye.
- - A disorder characterized by impaired eyelid function.
- - A disorder charactAlso consider EyeAddition: Navigational note
- - A disorder characAlso consider EyeAddition: Navigational note
Visual field defic - A disorder characterized by an inc Clarification: Grade 1, 2, 3, 4
Perforation; best - A disorder characAlso consider EyeAddition: Grade 1, Navigational note; Clarification: Grade
Best corrected vi - A disorder characterized by an inabi Clarification: Grade 2, 3, 4
Best corrected vi - A disorder characterized by involv Clarification: Grade 2, 3, 4
Best corrected vi - A disorder characterized by swellinClarification: Grade 1, 2, 3, 4
- - A disorder characterized by swellinPrimary SOC change
- - A disorder characterized by fear and avoidance of light.
Macula-off rhegm- A disorder characterized by the se Clarification: Grade 3, 4; Deletion: Grade 1, 2
- - A disorder characIf retinal detach Addition: Grade 1, Navigational note; Clarification: Grade
- - A disorder charactIf vitreous hemorAddition: Navigational note; Clarification: Grade 2, 3
Best corrected vi - A disorder involviIf vitreous hemorAddition: Navigational note; Clarification: Grade 2, 3, 4
Best corrected vi - A disorder characterized by involveClarification: Grade 1, 2, 3, 4
Best corrected vi - A disorder characterized by inflamClarification: Grade 1, 2, 3, 4
Best corrected vi - A disorder charactIf etiology is kn Addition: Term, Navigational note
Best corrected vi - A disorder characterized by bleedi Clarification: Grade 1, 2, 3, 4, Definition
Best corrected vi - A disorder characterized by excessiAddition: Grade 4; Clarification: Grade 2, 3, Definition
- - A disorder characterized by swelling of the abdomen.
- - A disorder characterized by a sensation of marked discomfort in the abdominal region.
- - A disorder characterized by a tear iAddition: Term
Life-threatening Death A disorder characterized by an abnClarification: Grade 1, 2, 3
Life-threatening Death A disorder characterized by bleedi Clarification: Grade 1, 2, 3
- - A disorder characReport Grade 4 anAddition: Navigational note; Clarification: Definition; Dele
Life-threatening Death A disorder characterized by a necroClarification: Grade 3
- - A disorder characterized by a sensation of marked discomfort in the anal region.
Life-threatening Death A disorder characterized by a narrowing of the lumen of the anal canal.
Life-threatening Death A disorder characterized by a circuClarification: Grade 3, Definition
Life-threatening Death A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal c
- - To expel gas nois Synonym: BurpinAddition: Term, Navigational note
- - A disorder characterized by subject-reported feeling of uncomfortable fullness of the abdom
Life-threatening Death A disorder characterized by bleed Clarification: Grade 1, 2, 3
- - A disorder characterized by inflammation of the lip.
Life-threatening Death A disorder characterized by accumul Addition: Term
Life-threatening Death A disorder characterized by inflamAddition: Navigational note; Clarification: Grade 3
Life-threatening Death A disorder characterized by an ab Clarification: Grade 1, 2, 3
Life-threatening Death A disorder characterized by blockagClarification: Grade 3
Life-threatening Death A disorder characterized by a ruptuClarification: Grade 2, 3
Life-threatening Death A disorder characterized by a narrowing of the lumen of the colon.
Life-threatening Death A disorder characterized by irregular and infrequent or difficult evacuation of the bowels.
- - A disorder characterized by the decay of a tooth, in which it becomes softened, discolored a
Life-threatening Death A disorder characterized by an in Clarification: Grade 2, 3, Definition
- - A disorder characterized by reduced salivary flow in the oral cavity.
Life-threatening Death A disorder characterized by an a Clarification: Grade 1, 2, 3
Life-threatening Death A disorder characterized by block Clarification: Grade 3
Life-threatening Death A disorder characterized by a rupt Clarification: Grade 2, 3
Life-threatening Death A disorder characterized by a nar Clarification: Grade 3
Life-threatening Death A disorder characterized by a circ Clarification: Grade 2, 3, Definition
- - A disorder characterized by an uncClarification: Grade 3
Life-threatening Death A disorder characterized by difficulClarification: Grade 3
Life-threatening Death A disorder characIf reporting a knoAddition: Navigational note
Life-threatening Death A disorder characterized by an a Clarification: Grade 1, 2, 3
Life-threatening Death A disorder characterized by blockaClarification: Grade 3
- - A disorder characterized by a sensation of marked discomfort in the esophageal region.
Life-threatening Death A disorder characterized by a narr Clarification: Grade 3
Life-threatening Death A disorder characterized by a circ Clarification: Grade 3, Definition
Life-threatening Death A disorder characterized by bleedi Clarification: Grade 3
Life-threatening Death A disorder characterized by inflamClarification: Grade 2, 3
- - A disorder characterized by inability to control the escape of stool from the rectum.
- - A disorder characterized by a dischClarification: Definition
Life-threatening Death A disorder characterized by an a Clarification: Grade 1, 2, 3, 4
Life-threatening Death A disorder characterized by bleedinClarification: Grade 1, 2, 3
Life-threatening Death A disorder characterized by a rupt Clarification: Grade 2, 3
Life-threatening Death A disorder characterized by inflammation of the stomach.
- - A disorder characterized by reflux Clarification: Grade 3
Life-threatening Death A disorder characterized by an ab Clarification: Grade 1, 2, 3, 4
- - A disorder characterized by a sensation of marked discomfort in the gastrointestinal region.
Life-threatening - A disorder characterized by an incoAddition: Grade 4; Clarification: Grade 3
- - A disorder characterized by a sensation of marked discomfort in the gingival region.
- - A disorder characterized by the pr Clarification: Grade 3
Life-threatening Death A disorder characterized by blockagClarification: Grade 2, 3
Life-threatening Death A disorder characterized by a rupturClarification: Grade 2, 3
Life-threatening Death A disorder characterized by a narrowing of the lumen of the ileum.
Life-threatening Death A disorder characterized by failureAddition: Grade 1; Clarification: Grade 3
Life-threatening Death A disorder characterized by bleedi Clarification: Grade 2, 3
Life-threatening Death A disorder characterized by a rupturClarification: Grade 2, 3
Life-threatening Death A disorder characterized by a narrowing of the lumen of the jejunum.
- - A disorder characterized by a sensation of marked discomfort of the lip.
Life-threatening Death A disorder characterized by inadequate absorption of nutrients in the small intestine. Symp
Life-threatening Death A disorder characterized by ulcera Clarification: Grade 2, Definition
- - A disorder characterized by a queasy sensation and/or the urge to vomit.
- - A disorder characterized by a burniClarification: Grade 3
- - A disorder characterized by a sensation of marked discomfort in the mouth, tongue or lips.
Life-threatening Death A disorder characterized by a narrowing of the lumen of the pancreatic duct.
Life-threatening Death A disorder characterized by infla Clarification: Grade 2, Definition
- - A disorder in the gingival tissue around the teeth.
Life-threatening Death A disorder characterized by a necr Clarification: Grade 3
Life-threatening Death A disorder characterized by inflamClarification: Grade 2
- - A disorder characterized by a tear iAddition: Term
Life-threatening Death A disorder characterized by ulcer Clarification: Definition
- - A disorder characterized by a sensation of marked discomfort in the rectal region.
Life-threatening Death A disorder characterized by a ruptur Clarification: Grade 2, 3
Life-threatening Death A disorder characterized by a narrowing of the lumen of the rectum.
Life-threatening Death A disorder characterized by inflamm Clarification: Grade 3
Life-threatening Death A disorder characterized by ulcera Clarification: Definition
Life-threatening Death A disorder characterized by blockagClarification: Grade 3, Definition
Life-threatening Death A disorder characterized by a narrowing of the lumen of the small intestine.
- - A disorder characterized by a sensation of marked discomfort in the stomach.
- - A disorder characterized by a pathClarification: Grade 3
- - A disorder characterized by a change in tooth hue or tint.
- - A disorder characterized by a sensation of marked discomfort in the tooth.
Life-threatening Death A disorder charactAlso report Inves Addition: Navigational note; Clarification: Definition
Life-threatening Death A disorder characterized by a decrePrimary SOC change
Life-threatening Death A disorder characterized by the re Clarification: Grade 1, 2, 3, 4
- - A disorder characterized by a sensation of cold that often marks a physiologic response to s
Neonatal loss of l - Newborn death occurring during the Addition: Grade 4; Clarification: Definition; Deletion: Grad
- Death Death that cannotIf death is due to Addition: Navigational note; Clarification: Definition
- Death Death due to diseIf death is due to Addition: Term, Navigational note
- - A disorder characterized by swelling due to excessive fluid accumulation in facial tissues.
- - A disorder characterized by swelling due to excessive fluid accumulation in the upper or low
- - A disorder characterized by swelling due to excessive fluid accumulation in the trunk area.
- - A disorder characterized by a sensation of marked discomfort in the face.
- - A disorder characterized by a state of generalized weakness with a pronounced inability to s
>40.0 degrees C (Death A disorder characterized by elevation of the body's temperature above the upper limit of no
- - A disorder charactSynonym: Flu, InfAddition: Navigational note
- - A disorder characterized by walkingClarification: Grade 3
Life-threatening - A disorder characterized by fluid a Addition: Term
<=28 degrees C; 8Death A disorder characterized by an abnormally low body temperature. Treatment is required wh
Life-threatening Death A disorder characterized by leakagAddition: Grade 1; Clarification: Definition
Life-threatening Death A disorder characterized by an intense adverse reaction (usually immunologic) developing a
- - A disorder charactPrior to using th Addition: Navigational note
- - A disorder characterized by a feeli Addition: Grade 3, Clarification: Grade 2
Life-threatening cDeath A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting
Vascular or respi - A disorder characterized by swellinAddition: Grade 4
- - A disorder characterized by a sens Clarification: Definition
- - A disorder characPrior to using th Addition: Navigational note
- Death An unexpected deaIf death is due to Addition: Navigational note; Clarification: Definition
- - A disorder characterized by lymph Addition: Term
Life-threatening Death A disorder characterized by a narroClarification: Grade 3
Life-threatening Death A disorder characterized by occlus Addition: Term
Life-threatening Death A disorder characterized by blockage of the normal flow of the contents of the gallbladder.
- - A disorder characterized by a sensation of marked discomfort in the gallbladder region.
Life-threatening Death A disorder characterized by a rupture in the gallbladder wall.
Life-threatening Death A disorder characterized by the inaClarification: Grade 3, 4, Definition
Life-threatening Death A disorder characterized by a necr Clarification: Grade 4
- - A disorder characterized by a sensation of marked discomfort in the liver region.
Life-threatening Death A disorder characterized by a ruptuClarification: Grade 3
Life-threatening Death A disorder characterized by an increase in blood pressure in the portal venous system.
Life-threatening Death A disorder characterized by the formation of a thrombus (blood clot) in the portal vein.
Life-threatening Death A disorder characterized by severeAddition: Term
Life-threatening Death A disorder characIf related to infu Addition: Navigational note; Clarification: Grade 1, 2, 3
Life-threatening Death A disorder characterized by an acute inflammatory reaction resulting from the release of his
Life-threatening Death A disorder characPrior to using th Addition: Navigational note; Clarification: Definition
Life-threatening Death A disorder characAlso consider repAddition: Navigational note; Clarification: Grade 1, 2, 3, 4
Life-threatening Death A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins der
Life-threatening Death A disorder characterized by an infeAddition: Grade 2; Clarification: Grade 3
Life-threatening Death A disorder characterized by an inf Clarification: Grade 1, 2, 3
Life-threatening Death A disorder characterized by acute Clarification: Grade 3
Life-threatening Death A disorder characterized by acute Clarification: Grade 3; Deletion: Grade 2
Life-threatening Death A disorder characterized by an infeClarification: Grade 3
- - A disorder characConsider InfectionAddition: Term, Navigational note
Life-threatening Death A disorder characterized by an infecAddition: Grade 2; Clarification: Grade 3
Life-threatening Death A disorder characterized by an infeClarification: Grade 2, 3
Life-threatening Death A disorder characterized by an inf Clarification: Grade 2, 3
Best corrected vi - A disorder characConsider InfectionAddition: Grade 4, Navigational note; Clarification: Grade
Life-threatening - A disorder characterized by an infeClarification: Grade 3; Deletion: Grade 5
Life-threatening Death A disorder characSynonym: CMV Addition: Term, Navigational note
Life-threatening Death A disorder characterized by an inf Clarification: Grade 3
Life-threatening Death A disorder characterized by an infectious process involving the brain tissue.
Best corrected vi - A disorder characterized by an infeClarification: Grade 3, 4
Life-threatening Death A disorder charactIncludes Clostridium
Addition: Navigational note; Clarification: Grade 2, 3
Life-threatening Death A disorder charactSynonym: EBV Addition: Term, Navigational note
- - A disorder characterized by inflammaAddition: Term
- - A disorder characterized by the pr Addition: Term
Life-threatening Death A disorder characterized by the reacAddition: Term
Life-threatening Death A disorder characterized by a viral Addition: Grade 2; Clarification: Grade 1, 3, 4
Life-threatening Death A disorder characterized by the reaAddition: Term
Life-threatening Death A disorder characterized by an infeAddition:
For symptoms Grade 2; consider
and no intervention, Clarification: Grade 3 thoracic and med
Respiratory,
Life-threatening Death A disorder charac Addition: Navigational note; Clarification: Grade 2, 3
- - A disorder characterized by an infeClarification: Grade 2, 3
Life-threatening Death A disorder characIf infection is du Addition: Navigational note; Clarification: Grade 2, 3, Defi
Life-threatening Death A disorder characterized by acute Clarification: Grade 3
Life-threatening Death A disorder characterized by inflamPrimary SOC change
Life-threatening Death A disorder characChanges associateAddition: Grade 1, 2, Navigational note; Clarification: Gra
Life-threatening Death A disorder characterized by an erupClarification: Grade 2, 3, 4, Definition
Life-threatening Death A disorder characterized by an infeAddition: Grade 1, 2; Clarification: Grade 3; Deletion Grad
Life-threatening Death A disorder characFor Grade 1 ConsiAddition: Navigational note; Clarification: Grade 2, 3
- - A disorder charactSynonym: Boil Addition: Navigational note; Clarification: Grade 3
- - A disorder characterized by an infeClarification: Grade 2
Life-threatening Death A disorder characIncludes SIRS. Al Addition: Grade 3, Navigational note
Life-threatening Death A disorder charactSynonym: HerpesAddition: Term, Navigational note
Life-threatening Death A disorder characterized by an infecClarification: Grade 2, 3, Definition
- - A disorder characterized by a suspeAddition: Term
- - A disorder characterized by the preAddition: Term
Life-threatening Death A disorder characterized by an inf Addition: Grade 1, 2; Clarification: Grade 3; Deletion Grad
- - A finding of damage to the ankle j Clarification: Grade 1, 2, 3
Life-threatening Death A finding of damage to the aorta. Addition: Grade 2; Clarification: Grade 3
Life-threatening Death A finding of damage to an artery. Clarification: Grade 2, 3
Life-threatening Death A finding of leakage of bile due to Clarification: Grade 1, 3
Life-threatening Death A finding of leakage of urine due Clarification: Grade 1, 3
- - A finding of injury of the soft tissues or bone characterized by leakage of blood into surroun
Life-threatening Death A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns ca
Life-threatening Death A finding of cutanSynonym: Radiatio Addition: Navigational note
Life-threatening Death A finding of leakage due to breakdClarification: Grade 1, 3
- - A finding of sudden movement downw Clarification: Grade 3
Life-threatening Death A finding of leakage due to breakdClarification: Grade 3
Life-threatening Death A disorder characterized by a ruptuClarification: Grade 2, 3, Definition; Deletion: Grade 1
Life-threatening Death A finding of traumPrior to using thi Addition: Navigational note; Clarification: Grade 3
Life-threatening Death A disorder characterized by a necroClarification: Grade 3, Definition
Life-threatening - A finding of traumatic injury to th Clarification: Grade 2
Life-threatening Death A disorder characterized by adverse Primary SOC change
Life-threatening Death A finding of damage to the carotid Addition: Grade 2
Life-threatening Death A finding of damage to the inferiorAddition: Grade 1, 2, 3
Life-threatening Death A finding of damage to the jugular Addition: Grade 2; Clarification: Grade 3
Life-threatening Death A finding of damage to the superioClarification: Grade 3, 4
Life-threatening Death A finding of leakage of contents fr Clarification: Grade 1, 3
Life-threatening Death A disorder characterized by blockagClarification: Definition
Life-threatening Death A disorder characterized by bleedi Clarification: Grade 3, Definition
Life-threatening Death A finding of damage to an artery dClarification: Grade 3
Life-threatening Death A finding of damage to the breast Clarification: Grade 3
Life-threatening Death A finding of damage to the heart during a surgical procedure.
Life-threatening Death A finding of damage to the ear durClarification: Grade 3
Life-threatening Death A finding of damage to the endocriClarification: Grade 3
Life-threatening Death A finding of damage to the gastroi Clarification: Grade 3
Life-threatening Death A finding of damage to the head anClarification: Grade 3
Life-threatening Death A finding of uncontrolled bleeding Clarification: Grade 3
Life-threatening Death A finding of damage to the hepaticClarification: Grade 3
Life-threatening Death A finding of damage to the musculoClarification: Grade 3
Life-threatening Death A finding of damage to the nervousClarification: Grade 3
Life-threatening Death A finding of damage to the eye durClarification: Grade 3
Life-threatening Death A finding of damage to the kidney Clarification: Grade 3
Life-threatening Death A finding of damage to the reproduClarification: Grade 3
Life-threatening Death A finding of damage to the respira Clarification: Grade 3
Life-threatening Death A finding of damage to the spleen Clarification: Grade 3
Life-threatening Death A finding of damage to the urinaryClarification: Grade 3
Life-threatening Death A finding of damage to a vein durinClarification: Grade 3
Life-threatening Death A finding of leakage of urine due Clarification: Grade 1, 3
Life-threatening Death A disorder characterized by bleedinClarification: Grade 1, 2, 3, Definition
Life-threatening Death A finding of a previously undocumented problem that occurs after a thoracic procedure.
Life-threatening Death A finding of protrusion of the intestinal stoma (surgically created opening on the surface of
Life-threatening Death A finding of displacement of the urostomy.
Life-threatening Death A finding of acute skin inflammatory reaction caused by drugs, especially chemotherapeutic
- - A finding of tumor-like collection oClarification: Grade 3
Life-threatening Death A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broke
Life-threatening Death A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surfa
- - A disorder characterized by a circ Clarification: Definition
Life-threatening Death A disorder characterized by bleedi Clarification: Grade 1, 2, 3, Definition
Life-threatening Death A disorder characterized by blockaClarification: Grade 3, Definition
Life-threatening Death A finding of leakage of contents f Clarification: Grade 1, 3
Life-threatening Death A disorder characterized by blockaClarification: Grade 1, Definition
Life-threatening Death A finding of narrowing of the openClarification: Grade 2
Life-threatening Death A disorder characterized by a ruptuClarification: Grade 2, 3; Deletion: Grade 1
Life-threatening - A disorder that o For systemic vaccAddition: Term, Navigational note
Life-threatening Death A finding of a previously undocumeAddition: Grade 1; Clarification Grade 3, 4
Life-threatening Death A finding of damage to a vein. Clarification: Grade 3
Life-threatening Death A finding of deve Prior to using th Addition: Navigational note; Clarification: Grade 1, 2, 3, 4
Life-threatening Death A finding of sepa Also consider Inf Addition: Navigational note; Clarification: Grade 1, 2, 3
- - A finding of traumatic injury to theClarification: Grade 1, 2, 3
- - A finding based on laboratory test Clarification: Grade 3, Definition
>20.0 x ULN if ba - A finding based oAlso consider Hepa Addition: Navigational note; Clarification: Grade 1, 2, 3, 4
>20.0 x ULN if ba - A finding based on laboratory test Clarification: Grade 1, 2, 3, 4
>20.0 x ULN if ba - A finding based oAlso consider Hepa Addition: Navigational note; Clarification: Grade 1, 2, 3, 4
- - A finding based on laboratory test results that indicate abnormal levels of antidiuretic horm
- - A finding based oAlso consider MetAddition: Term, Navigational note
>10.0 x ULN if ba - A finding based onAlso consider HepaAddition: Navigational note; Clarification: Grade 1, 2, 3, 4
- - A finding based on laboratory test results that indicate an decrease in levels of corticotroph
- - A finding based on laboratory test results that indicate abnormal levels of gonadotrophin ho
- - A finding based on laboratory test Addition: Term
- - A finding based on laboratory test results that indicate abnormal levels of prolactin hormon
- - A finding based oAlso consider ResAddition: Navigational note; Clarification: Grade 1, 2, 3
- - A finding based onAlso consider CardAddition: Navigational note; Clarification: Definition
- - A finding based onAlso consider CardAddition: Navigational note; Clarification: Definition
<50/mm3; <0.05 x- A finding based on laboratory test results that indicate an decrease in levels of CD4 lympho
>500 mg/dL; >12 - A finding based on laboratory test results that indicate higher than normal levels of choleste
>10 x ULN - A finding based oAlso consider Card Addition: Navigational note
>6.0 x ULN - A finding based onAlso consider RenAddition: Navigational note; Clarification: Grade 1, 3
Resting ejection - The percentage co Also consider Card Addition: Navigational note; Clarification: Grade 3
Torsade de pointe- A finding of a cardiac dysrhythmia Clarification: Grade 1, 2, 3, 4
- - A disorder characterized by Elect Addition: Term
<0.25 x LLN; if a - A finding based on laboratory test Clarification: Grade 1, 2, 3, 4
<= 49% - A finding based onAlso consider ResAddition: Navigational note
>20.0 x ULN if ba - A finding based on laboratory tes Clarification: Grade 1, 2, 3, 4
- - A finding based on laboratory test results that indicate abnormal levels of growth hormone
- - A finding based on laboratory test results that indicate an decrease in levels of haptoglobin
- - A finding based on laboratory test Clarification: Grade 1, 2, 3, Definition
- - A finding based on laboratory test Clarification: Grade 1, 2, 3
>5.0 x ULN and w - A finding based on laboratory test C r larification: Grade 2, 3, 4
<200/mm3; <0.2 x- A finding based on laboratory test results that indicate a decrease in number of lymphocyte
- - A finding based on laboratory test results that indicate an abnormal increase in the number
<500/mm3; <0.5 x- A finding based on laboratory test results that indicate a decrease in number of neutrophils
- - A finding based on laboratory test results that indicate an decrease in levels of pancreatic e
<25,000/mm3; <25 - A finding based on laboratory test results that indicate a decrease in number of platelets in
>5.0 x ULN and w - A finding based on laboratory test Clarification: Grade 2, 3, 4
- - A disorder characIf intervention i Addition: Term, Navigational note
Pediatric: No urine- output over 12Ahours
finding based on test results thatClarification: Grade 3, 4
- - A finding based oAlso consider Inv Addition: Navigational note
- - A finding charact Do not use Metabo Addition: Navigational note; Clarification: Definition
- - A finding characterized by a decrease in overall body weight; for pediatrics, less than the ba
<1000/mm3; <1.0- A finding based on laboratory test results that indicate an decrease in number of white bloo
Life-threatening Death A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of th
Life-threatening Death A disorder characterized by an increase in sensitivity to the adverse effects of alcohol, which
Life-threatening Death A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of
Life-threatening Death A disorder characterized by a loss of appetite.
Life-threatening Death A disorder characterized by excessiClarification: Grade 2, 3
Life-threatening Death A disorder characterized by an inability to properly metabolize glucose.
Corrected serum D c eath A disorder characterized by laboratory test results that indicate an elevation in the concent
Life-threatening Death A disorder characterized by laborato Clarification: Grade 1, 2, 3, 4
>7.0 mmol/L; lif Death A disorder characterized by laboratClarification: Grade 2
Life-threatening - A disorder characterized by laborato Addition: Term
>8.0 mg/dL; >3.3 Death A disorder characterized by laboratory test results that indicate an elevation in the concent
>160 mmol/L; lif Death A disorder characterized by laboratClarification: Grade 2
Life-threatening cDeath A disorder characterized by laboratAddition: Term
>1000 mg/dL; >11Death A disorder characterized by laboratory test results that indicate an elevation in the concent
Life-threatening Death A disorder characterized by laborato Clarification: Grade 1, 3, 4
Life-threatening Death A disorder characterized by laboratory test results that indicate a low concentration of albu
Corrected serum D c eath A disorder characterized by laboratory test results that indicate a low concentration of calci
<30 mg/dL; <1.7 m Death A disorder characterized by laboratory test results that indicate a low concentration of gluc
<2.5 mmol/L; lif Death A disorder characterized by laboratClarification: Grade 2
<0.7 mg/dL; <0.3 Death A disorder characterized by laboratory test results that indicate a low concentration of mag
<120 mmol/L; lif Death A disorder characterized by laboratAddition: Grade 2; Clarification: Grade 3
Life-threatening Death A disorder characterized by laboratClarification: Grade 1, 2, 3, 4
Life-threatening Death A disorder characterized by accumulation of iron in the tissues.
BMI >=40 kg/m2 - A disorder characUse term InvestigAddition: Navigational note
Life-threatening Death A disorder characterized by metabolic abnormalities that result from a spontaneous or ther
- - A disorder characterized by a sensation of marked discomfort in a joint.
- - A disorder characterized by inflamm Clarification: Grade 3
Life-threatening Death A disorder characUse new term: Mus Addition: Navigational note
Life-threatening Death A disorder characterized by a necrotAddition: Term
- - A disorder characterized by non-neoplastic overgrowth of bone.
Generalized; assoDeath A disorder characterized by fibroti Clarification: Grade 3
- - A disorder characterized by a sensaClarification: Definition
- - A disorder characterized by a reducClarification: Grade 1, 2, 3
- - A disorder characterized by statureClarification: Definition
- - A disorder characterized by excessivClarification: Grade 3
- - A disorder characterized by a decreas
Clarification: Grade 3
- - A disorder characterized by a decrease in flexibility of a cervical spine joint.
- - A disorder characterized by a decrease in flexibility of a lumbar spine joint.
- - A disorder characterized by an abnormal increase in the curvature of the thoracic portion o
- - A disorder characterized by an abnormal increase in the curvature of the lumbar portion of
- - A disorder characSynonym: MuscleAddition: Term, Navigational note
- - A disorder characterized by a reducClarification: Grade 3
- - A disorder characterized by a reducClarification: Grade 3
- - A disorder characterized by a reduClarification: Grade 3
- - A disorder characterized by a malf Clarification: Grade 3, Definition
- - A disorder characterized by marked discomfort sensation originating from a muscle or grou
Life-threatening - A disorder characterized by inflamAddition: Grade 4
Life-threatening Death A disorder characterized by necrotiAddition: Term
Life-threatening Death A disorder characterized by a necrotic process occurring in the bone of the mandible.
- - A disorder characterized by reduceClarification: Grade 1, 2, 3
Life-threatening Death A disorder characterized by a necrotClarification: Grade 3
Life-threatening Death A disorder characterized by the br Addition: Term
- - A disorder characterized by an injurAddition: Term
- - A disorder characterized by a malfoClarification: Grade 3
Generalized; assoDeath A disorder characterized by fibrotic degeneration of the superficial soft tissues.
- - A disorder characterized by lack of ability to open the mouth fully due to a decrease in the r
- - A disorder characterized by a disc Clarification: Grade 3, Definition
Present Death A disorder characterized by leukemia arising as a result of the mutagenic effect of chemoth
Life-threatening Death A disorder characterized by insufficiently healthy hematapoietic cell production by the bone
- - A disorder characterized by the pr Addition: Term
Acute life-threat Death A disorder characterized by development of a malignancy most probably as a result of treat
Life-threatening Death A disorder characterized by bleedi Addition: Term
- - A disorder characterized by dysfuncClarification: Definition
- - A disorder characterized by an uncomfortable feeling of inner restlessness and inability to s
- - A disorder characterized by systematic and extensive loss of memory.
- - A disorder characAlso consider Olf Addition: Term, Navigational note
- - A disorder characterized by the inability to speak. It may result from injuries to the vocal co
Life-threatening Death A disorder characterized by inflammation of the arachnoid membrane and adjacent subarac
- - A disorder characterized by lack of coordination of muscle movements resulting in the impa
- - A disorder characterized by regional paresthesia of the brachial plexus, marked discomfort a
Life-threatening Death A disorder characterized by a necrotic process occurring in the brain and/or spinal cord.
Life-threatening Death A disorder characterized by loss of cerebrospinal fluid into the surrounding tissues.
- - A disorder characterized by a conspicuous change in cognitive function.
- - A disorder characterized by a deterioration in the ability to concentrate.
Life-threatening Death A disorder characterized by a decreClarification: Grade 4
- - A disorder characterized by a disturbing sensation of lightheadedness, unsteadiness, giddin
- - A disorder characterized by slow and slurred speech resulting from an inability to coordinat
- - A disorder characterized by distortion of sensory perception, resulting in an abnormal and u
- - A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can
- - A disorder characterized by impairment of verbal communication skills, often resulting from
Life-threatening Death A disorder characterized by swellinAddition: Grade 3, 5
Life-threatening Death A disorder characterized by a pathologic process involving the brain.
Life-threatening Death A disorder characSynonym: Restless Addition: Navigational note
- - A disorder characterized by a reduction in the strength of the facial muscles.
Life-threatening Death A disorder characterized by dysfunClarification: Definition
Life-threatening Death A disorder characterized by the boAddition: Term
- - A disorder characterized by a sensation of marked discomfort in various parts of the head, n
Life-threatening Death A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of
- - A disorder characterized by characterized by excessive sleepiness during the daytime.
- - A disorder characPrior to using th Addition: Navigational note
- - A disorder characterized by a decrease in consciousness characterized by mental and physic
Life-threatening Death A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci
- - A disorder characterized by a deterioration in memory function.
Life-threatening Death A disorder characterized by neck stiffness, headache, and photophobia resulting from irritati
- - A disorder characterized by uncontrolled and purposeless movements.
- - A disorder characterized by a reducClarification: Grade 3; Primary SOC change
- - A disorder characterized by a reducClarification: Grade 3; Primary SOC change
Life-threatening Death A disorder characterized by weakne Addition: Term
- - A disorder characterized by intense painful sensation along a nerve or group of nerves.
- - A disorder characterized by involuntary movements of the eyeballs.
- - A disorder characterized by dysfunct
Clarification: Definition
- - A disorder characterized by functi Clarification: Definition
Life-threatening Death A disorder characAlso consider NerAddition: Navigational note; Clarification: Grade 1, 3, Defi
Life-threatening - A disorder characterized by damage Clarification: Grade 1, Definition; Deletion: Grade 5
- - A disorder characterized by an episode of lightheadedness and dizziness which may precede
Life-threatening Death A disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal
Life-threatening Death A disorder characterized by inflamClarification: Grade 2
Life-threatening Death A disorder characterized by paralysis of the recurrent laryngeal nerve.
Life-threatening Death A disorder characterized by headacClarification: Grade 2, 3, 4, Definition; Deletion: Grade 1
Life-threatening Death A disorder characterized by a suddeClarification: Grade 1, 3, 4
Life-threatening Death A disorder characterized by characterized by excessive sleepiness and drowsiness.
Life-threatening Death A disorder characterized by increa Clarification: Grade 4
Life-threatening Death A disorder characterized by pressurAddition: Term
Life-threatening Death A disorder characterized by a decr Clarification: Grade 1, 2, 3, Definition
- - A disorder characterized by spontaneous loss of consciousness caused by insufficient blood
- - A disorder characAlso consider NerAddition: Term, Navigational note
- - A disorder charactIf >24 hours, ConAddition: Navigational note
- - A disorder characterized by the uncontrolled shaking movement of the whole body or indiv
- - A disorder characterized by dysfuncAddition: Term
Life-threatening Death A disorder characterized by dysfuncClarification: Definition
Life-threatening Death A disorder characterized by a sudden drop of the blood pressure, bradycardia, and peripher
<1% percentile of - A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to
Fetal loss at any - Death in utero. Addition: Term
Life-threatening Death - Clarification: Grade 2, 3
Delivery of a live - A disorder characterized by delivery of a viable infant before the normal end of gestation. T
Life-threatening - A disorder characterized by a stateDeletion: Grade 5
- - A disorder characterized by an inability to achieve orgasm.
Life-threatening - A disorder characterized by apprehClarification: Grade 3, 4; Deletion: Grade 5
Life-threatening - A disorder characterized by a lack Deletion: Grade 5
- - A disorder characterized by sexual dysfunction characterized by a delay in climax.
Life-threatening Death A disorder characterized by the acuClarification: Grade 3, 4
Life-threatening Death A disorder characterized by false Clarification: Grade 3, 4
Life-threatening Death A disorder characterized by melanch Clarification: Grade 4
- - A disorder characterized by an exaggerated feeling of well-being which is disproportionate t
Life-threatening Death A disorder characterized by a falseClarification: Grade 4
- - A disorder characterized by difficulty in falling asleep and/or remaining asleep.
- - A disorder characterized by an abno Clarification: Grade 3; Primary SOC change
- - A disorder characterized by a decrease in sexual desire.
- - A disorder characterized by an incrClarification: Grade 1; Deletion: Grade 2, 3
Life-threatening Death A disorder characterized by excite Clarification: Grade 3, 4
Life-threatening - A disorder characterized by a consClarification: Grade 4; Deletion: Grade 5
Life-threatening Death A disorder characterized by persona Clarification: Grade 3, 4
- - A disorder characterized by an inability to rest, relax or be still.
Specific plan to c - A disorder characterized by thoughts of taking one's own life.
Suicide attempt wDeath A disorder characterized by self-in Clarification: Grade 3
Life-threatening Death A disorder charactAlso consider Inv Addition: Navigational note; Clarification: Grade 3, Defini
- - A disorder characterized by a sudden and involuntary contraction of the bladder wall.
eGFR or CrCl <15 Death A disorder characterized by gradual and usually permanent loss of kidney function resulting
Life-threatening Death A disorder characterized by inflamm Clarification: Grade 3, 4
- - A disorder charactIf associated withAddition: Term, Navigational note
- - A disorder characterized by laboratoAddition: Term
Life-threatening Death A disorder characterized by laboratoClarification: Grade 3, 4
- - A disorder characReport underlyingAddition: Navigational note
Life-threatening Death A disorder characterized by symptoAddition: Term
- - A disorder charact24-hour urine colAddition: Navigational note; Clarification: Grade 1, 2, 3
Life-threatening Death - Clarification: Grade 2, 3
Life-threatening Death A disorder characterized by the forClarification: Grade 3, 4, Definition
- - A disorder characterized by paroxys Clarification: Definition
- - A disorder characterized by urination at short intervals.
- - A disorder characterized by inability to control the flow of urine from the bladder.
Life-threatening Death A disorder characterized by accumul Clarification: Grade 3
Life-threatening Death A disorder characterized by blockagClarification: Grade 1, 2, 3
- - A disorder characterized by a sensation of marked discomfort in the urinary tract.
- - A disorder characterized by a sudden compelling urge to urinate.
- - A disorder characterized by a change in the color of the urine.
- - A disorder characterized by the abAddition: Term
- - A disorder characterized by laboraAddition: Grade 2; Deletion: Grade 3
- - A disorder characterized by underdevelopment of the breast.
- - A disorder characterized by abnormally painful abdominal cramps during menses.
- - A disorder characterized by painful or difficult coitus.
- - A disorder characterized by problems related to ejaculation. This category includes prematu
- - A disorder characterized by the persistent or recurrent inability to achieve or to maintain an
- - A disorder characterized by blockagClarification: Grade 1, 2, 3
- - A disorder characterized by the development of secondary female sex characteristics in ma
- - A disorder characterized by swelling due to an excessive accumulation of fluid in the genital
- - A disorder characterized by excessClarification: Grade 1
Life-threatening Death A disorder characterized by the preClarification: Grade 3
- - A disorder characAlso consider Re Addition: Navigational note; Clarification: Grade 1, 2, Defi
- - A disorder characterized by disturbances of milk secretion. It is not necessarily related to pr
Life-threatening Death A disorder characterized by abnor Clarification: Grade 3
- - A disorder characterized by a malformation of the nipple.
- - A disorder characterized by a dec Clarification: Grade 1; Deletion: Grade 2, 3
Life-threatening Death A disorder characterized by bleedi Clarification: Grade 1, 2, 3, 4
Life-threatening Death A disorder characterized by tearingClarification: Grade 3
- - A disorder characterized by a sens Clarification: Grade 2, Definition; Deletion: Grade 1, 3
- - A disorder characterized by a reducDeletion: Grade 4, 5
- - A disorder characterized by a sensation of marked discomfort in the area between the genit
- - A disorder characterized by prematAddition: Grade 2; Clarification: Definition; Deletion: Grad
- - A disorder characterized by compresClarification: Grade 1, 2, 3
- - A disorder characterized by a sensation of marked discomfort in the prostate gland.
- - A disorder characterized by blockaClarification: Grade 1, 2, 3
Life-threatening - A disorder characAlso consider RepAddition: Navigational note; Clarification: Grade 2, 3, Defi
Life-threatening Death A disorder characterized by bleedinClarification: Grade 1, 2, 3, 4
- - A disorder characterized by a sensation of marked discomfort in the testis.
- - A disorder characterized by a sensation of marked discomfort in the uterus.
- - A disorder characterized by vaginal secretions. Mucus produced by the cervical glands is dis
- - A disorder characterized by an uncomfortable feeling of itching and burning in the vagina.
Life-threatening - A disorder characterized by infla Clarification: Grade 4; Deletion: Grade 5
- - A disorder characterized by a sensation of marked discomfort in the vagina.
Life-threatening Death A disorder characterized by a ruptuClarification: Grade 2, 3; Deletion: Grade 1
- Death A disorder characterized by a narrowing of the vaginal canal.
Life-threatening Death A disorder characterized by progressive and life-threatening pulmonary distress in the abse
- - A disorder characterized by an inflammation of the nasal mucous membranes caused by an
Life-threatening Death A disorder characterized by cessation of breathing.
Life-threatening Death A disorder characterized by inhalation of solids or liquids into the lungs.
Life-threatening Death A disorder characterized by the colClarification: Grade 3
Life-threatening Death A disorder characterized by blockage of a bronchus passage, most often by bronchial secreti
Life-threatening Death A disorder characterized by a narrowing of the bronchial tube.
Life-threatening Death A disorder characterized by a suddClarification: Grade 3
Life-threatening Death A disorder characterized by milky pClarification: Grade 2
- - A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic
Life-threatening Death A disorder characterized by an uncomfortable sensation of difficulty breathing.
- - A disorder characterized by repeated gulp sounds that result from an involuntary opening a
- - A disorder characterized by harsh and raspy voice arising from or spreading to the larynx.
Life-threatening Death A disorder characterized by a decrease in the level of oxygen in the body.
Life-threatening Death A disorder characterized by swelling due to an excessive accumulation of fluid in the larynx.
- - A disorder characterized by an inflammation involving the larynx.
Life-threatening Death A disorder characterized by ulcer Clarification: Grade 2, Definition
Life-threatening Death A disorder characterized by an uncClarification: Grade 2
Persistent or seveDeath A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords.
- - A disorder characterized by obstruction of the nasal passage due to mucosal edema.
- - A disorder characterized by a sens Addition: Term
Life-threatening Death A disorder characterized by ulcer Clarification: Grade 2, Definition
Life-threatening Death A disorder characterized by an inc Clarification: Grade 2, 3
Life-threatening Death A disorder characterized by bleedinClarification: Grade 3, 4
Life-threatening Death A disorder characterized by inflammation focally or diffusely affecting the lung parenchyma
Life-threatening Death A disorder characterized by abnormaClarification: Grade 2
- - A disorder characterized by excessive mucous secretion in the back of the nasal cavity or th
- - A disorder characterized by expectorated secretions upon coughing.
Life-threatening Death A disorder characterized by accumulation of fluid in the lung tissues that causes a disturban
Life-threatening Death A disorder characterized by the repClarification: Grade 1, 2, 3
Life-threatening Death A disorder characterized by an incrClarification: Grade 3
Life-threatening Death A disorder characterized by impaireClarification: Definition
Life-threatening Death A disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocy
- - A disorder characterized by excessAddition: Term
Necrosis of soft t Death A disorder characterized by involvement of the paranasal sinuses.
- - A disorder characterized by a sens Clarification: Definition; Primary SOC change
Cardiovascular orDeath A disorder characterized by cessatiClarification: Grade 3
- - A disorder characterized by the involuntary expulsion of air from the nose.
- - A disorder characterized by markedClarification: Definition
Life-threatening Death A disorder characterized by a high pitched breathing sound due to laryngeal or upper airwa
Life-threatening Death A disorder characterized by an in Clarification: Definition
Life-threatening Death A disorder characterized by a narr Clarification: Grade 2, 3
- - A disorder characterized by a change in the sound and/or speed of the voice.
Life-threatening Death A disorder characterized by a high-pitched, whistling sound during breathing. It results from
- - A disorder characterized by a decrease in density of hair compared to normal for a given ind
- - A disorder characterized by an abnormal body smell resulting from the growth of bacteria o
Blisters covering Death A disorder charactIf infectious, con Addition: Navigational note
- - A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a
- - A disorder characterized by skin whAddition: Term
Target lesions co Death A disorder characterized by target lesions (a pink-red ring around a pale center).
Erythema covering Death A disorder characterized by generalized inflammatory erythema and exfoliation. The inflam
- - A disorder characterized by shrinking of adipose tissue.
- - A disorder characterized by changeAddition: Term
- - A disorder characterized by a chang Addition: Term
- - A disorder characterized by the presence of excess hair growth in women in anatomic sites
- - A disorder characSynonym: Night sAddition: Navigational note; Clarification: Grade 3, Defini
- - A disorder characterized by a thicke Addition: Term
- - A disorder characterized by hair density or length beyond the accepted limits of normal in a
Heat stroke Death A disorder characterized by reduced sweating.
- - A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of m
- - A disorder characterized by a chang Addition: Term
- - A disorder characterized by a change Clarification: Grade 1
- - A disorder characterized by loss of all or a portion of the nail.
- - A disorder characterized by vertical or horizontal ridges on the nails.
- - A disorder characterized by rednesClarification: Grade 2, 3, Definition
Life-threatening Death A disorder characterized by an increase in sensitivity of the skin to light.
- - A disorder characterized by an inteClarification: Grade 2, 3
- - A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer le
Life-threatening Death A disorder characterized by an erupClarification: Grade 2, 3, 4
- - A disorder characterized by the pr Clarification: Grade 2, 3
- - A disorder characterized by the degeneration and thinning of the epidermis and dermis.
- - A disorder characterized by darkening of the skin due to excessive melanin deposition.
- - A disorder characterized by loss of Clarification:
s Definition
Generalized; assoDeath A disorder characterized by an areaClarification: Grade 3
Any size ulcer witDeath A disorder characterized by a circuClarification: Definition
Skin sloughing c Death A disorder characterized by less t Clarification: Grade 3
- - A disorder characterized by air in Addition: Term
- - A disorder characterized by local dClarification: Grade 2
Skin sloughing c Death A disorder characterized by greater than 30% total body skin area separation of dermis. The
- - A disorder characterized by an itchy skin eruption characterized by wheals with pale interio
Life-threatening Death A disorder charactConsider NervousAddition: Term, Navigational note
Life-threatening Death A disorder characterized by leakageAddition: Grade 1
- - A disorder characterized by episodiClarification: Grade 1, 2, Definition
Life-threatening Death A disorder characterized by a localiClarification: Grade 3
- - A disorder characterized by an uncomfortable and temporary sensation of intense body wa
Adult and Pediatric:
Death
Life-threatening
A disorder
consequences
characterized
(e.g., malignant
by a patho
hypertension,
Clarification: Grade
transient
1, 2,or3,permanent
4, Definition
neurologic deficit, h
Life-threatening Death A disorder characterized by a bloo Clarification: Grade 3, 4
Life-threatening Death A disorder characterized by the losClarification: Grade 3
- - A disorder characterized by excessive fluid collection in tissues that causes swelling.
- - A disorder characterized by a cystiClarification: Grade 3
Life-threatening Death A disorder characterized by impaireClarification: Grade 2, 3
- - A disorder characterized by inflammation of the wall of a vein.
- - A disorder characterized by a blood clot and inflammation involving a superficial vein of the
Life-threatening Death A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs an
Life-threatening Death A disorder characConsider NervousAddition: Navigational note; Clarification: Grade 1, 2, 3, 4
ow to produce hematopoietic elements.
on of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as th
ngle temperature of >38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one ho
dicate an increased number of white blood cells in the blood.

mfort in a lymph node.
on or structure.
c electrical activity. Typically, this is accompanied by cessation of the pumping function of the heart.
the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of
ction of the heart.
note; Clarification: Grade 2, 3, Definition
note; Clarification: Grade 2, 3

note; Clarification: Definition
on or structure.
sively lengthening PR interval prior to the blocking of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse c
dium; this is due to an interruption of blood supply to the area.
3; Deletion: Grade 1
regular and/or forceful beating of the heart.
icardial sac, usually due to inflammation.

l pressure due to the collection of blood or fluid in the pericardium.
pericardium (the protective sac around the heart).
unction or structure.
larification: Grade 3
te greater than 100 beats per minute that originates in the sinus node.
ction or structure.
mfort in the ear.
mfort in the external ear region.
ponse to irritation), swelling and redness to the middle ear.

ing, buzzing, roaring or clicking.
world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo).
and vision problems.
emble Cushing's disease or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to
parathyroid hormone by the parathyroid glands. This results in hypercalcemia (abnormally high levels of calcium in the blood).
rmone in the body. Common causes include an overactive thyroid gland or thyroid hormone overdose.
arathyroid hormone by the parathyroid glands.
hyroid hormone by the thyroid gland.

of secondary sexual features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys.
n occurring in a female or prepubertal male.

ification: Grade 2, 3
note; Clarification: Grade 1, 2, 3
ification: Grade 2, 3
mfort in the eye.
igational note; Clarification: Grade 2, 3, 4
4; Deletion: Grade 1, 2
igational note; Clarification: Grade 2; Deletion: Grade 3, 4
2, 3, 4, Definition
ification: Grade 2, 3, Definition
mfort in the abdominal region.
note; Clarification: Definition; Deletion: Grade 4, 5
mfort in the anal region.

he anal canal.
morrhagic fluid in the peritoneal cavity.
ncomfortable fullness of the abdomen.
note; Clarification: Grade 3
fficult evacuation of the bowels.

h it becomes softened, discolored and/or porous.
3, Definition
3, Definition
mfort in the esophageal region.
e of stool from the rectum.
mfort in the gastrointestinal region.

ification: Grade 3
mfort in the gingival region.
ification: Grade 3
he jejunum.
mfort of the lip.
rients in the small intestine. Symptoms include abdominal marked discomfort, bloating and diarrhea.
e urge to vomit.
mfort in the mouth, tongue or lips.
he pancreatic duct.
mfort in the rectal region.
he small intestine.
mfort in the stomach.
mfort in the tooth.

marks a physiologic response to sweating after a fever.

ification: Definition; Deletion: Grade 5
d accumulation in facial tissues.

d accumulation in the upper or lower extremities.
d accumulation in the trunk area.
mfort in the face.
ess with a pronounced inability to summon sufficient energy to accomplish daily activities.
erature above the upper limit of normal.
perature. Treatment is required when the body temperature is 35C (95F) or below.
ification: Definition
usually immunologic) developing at the site of an injection.
ification: Grade 2
he lungs, liver, kidney and clotting mechanisms.
of the contents of the gallbladder.

mfort in the gallbladder region.
4, Definition
mfort in the liver region.
in the portal venous system.

(blood clot) in the portal vein.

on resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clin
note; Clarification: Grade 1, 2, 3, 4, Definition
ty reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration
ification: Grade 3
Deletion: Grade 2
ification: Grade 3
ification: Grade 3
igational note; Clarification: Grade 2, 3; Primary SOC change

Deletion: Grade 5
ification: Grade 3
g the brain tissue.
ification: Grade 3
ification: Grade 3
ification: Grade 1, 3, 4
ification: Grade 3

avigational note; Clarification: Grade 3; Deletion Grade 2
3, 4, Definition
larification: Grade 3; Deletion Grade 2


igational note
3, Definition
ification: Grade 3
d by leakage of blood into surrounding tissues.
adverse thermal reaction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of dama
3, Definition; Deletion: Grade 1

ification: Grade 3
2, 3, Definition
curs after a thoracic procedure.
created opening on the surface of the body) above the abdominal surface.
drugs, especially chemotherapeutic agents, for weeks or months following radiotherapy. The inflammatory reaction is confined to the prev
ntinuity of a vertebral bone is broken.

ically created opening on the surface of the body).
2, 3, Definition
ification Grade 3, 4
note; Clarification: Grade 1, 2, 3, 4


bnormal levels of antidiuretic hormone in the blood specimen.

n decrease in levels of corticotrophin in a blood specimen.
bnormal levels of gonadotrophin hormone in a blood specimen.
bnormal levels of prolactin hormone in a blood specimen.

n decrease in levels of CD4 lymphocytes in a blood specimen.
gher than normal levels of cholesterol in a blood specimen.
bnormal levels of growth hormone in a biological specimen.

n decrease in levels of haptoglobin in a blood specimen.
2, 3, Definition
decrease in number of lymphocytes in a blood specimen.

n abnormal increase in the number of lymphocytes in the blood, effusions or bone marrow.
decrease in number of neutrophils in a blood specimen.
n decrease in levels of pancreatic enzymes in a biological specimen.
decrease in number of platelets in a blood specimen.

ght; for pediatrics, less than the baseline growth curve.
n decrease in number of white blood cells in a blood specimen.
hydrogen-ion concentration) of the blood and other body tissues.
he adverse effects of alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and head
w hydrogen-ion concentration) of the blood and other body tissues.
bolize glucose.
dicate an elevation in the concentration of calcium (corrected for albumin) in blood.
dicate an elevation in the concentration of magnesium in the blood.
dicate an elevation in the concentration of triglyceride concentration in the blood.
dicate a low concentration of albumin in the blood.

dicate a low concentration of calcium (corrected for albumin) in the blood.
dicate a low concentration of glucose in the blood.
dicate a low concentration of magnesium in the blood.
ification: Grade 3
result from a spontaneous or therapy-related cytolysis of tumor cells.
mfort in a joint.
ervical spine joint.

umbar spine joint.
curvature of the thoracic portion of the spine.
curvature of the lumbar portion of the spine.
originating from a muscle or group of muscles.
n the bone of the mandible.

uperficial soft tissues.
uth fully due to a decrease in the range of motion of the muscles of mastication.
f the mutagenic effect of chemotherapy agents.

poietic cell production by the bone marrow.
y most probably as a result of treatment for a previously existing malignancy.
nner restlessness and inability to stay still; this is a side effect of some psychotropic drugs.
of memory.
result from injuries to the vocal cords or may be functional (psychogenic).

d membrane and adjacent subarachnoid space.
e movements resulting in the impairment or inability to perform voluntary activities.
rachial plexus, marked discomfort and muscle weakness, and limited movement in the arm or hand.
n the brain and/or spinal cord.
o the surrounding tissues.
nitive function.
o concentrate.
theadedness, unsteadiness, giddiness, spinning or rocking.

lting from an inability to coordinate the muscles used in speech.
tion, resulting in an abnormal and unpleasant sensation.
with the taste of foodstuffs; it can be related to a decrease in the sense of smell.
nication skills, often resulting from brain damage.
the facial muscles.
mfort in various parts of the head, not confined to the area of distribution of any nerve.
brospinal fluid in the ventricles of the brain.
eepiness during the daytime.
characterized by mental and physical inertness.
with multiple areas of necrotic foci without inflammation.
photophobia resulting from irritation of the cerebral meninges.

s movements.
Primary SOC change
Primary SOC change
ng a nerve or group of nerves.

Definition; Deletion: Grade 5
ss and dizziness which may precede an episode of syncope.

nal (pyramidal) tracts of the spinal cord. Symptoms include an increase in the muscle tone in the lower extremities, hyperreflexia, positive
yngeal nerve.
3, 4, Definition; Deletion: Grade 1
eepiness and drowsiness.
2, 3, Definition
sness caused by insufficient blood supply to the brain.
vement of the whole body or individual parts.
ressure, bradycardia, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase in the stimulation of th
ulting in the inability of the fetus to achieve its potential weight.
ore the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation.
zed by a delay in climax.

ll-being which is disproportionate to events and stimuli.
/or remaining asleep.

Primary SOC change
Deletion: Grade 2, 3
Deletion: Grade 5
note; Clarification: Grade 3, Definition; Deletion: Grade 1, 2
ntraction of the bladder wall.

nt loss of kidney function resulting in renal failure.
4, Definition
f urine from the bladder.
mfort in the urinary tract.
etion: Grade 3
l cramps during menses.

on. This category includes premature, delayed, retrograde and painful ejaculation.
ability to achieve or to maintain an erection during sexual activity.
ry female sex characteristics in males due to extrinsic factors.

accumulation of fluid in the genitals.
note; Clarification: Grade 1, 2, Definition; Deletion: Grade 3

n. It is not necessarily related to pregnancy that is observed in females and can be observed in males.
Deletion: Grade 2, 3
Definition; Deletion: Grade 1, 3
mfort in the area between the genital organs and the anus.
ification: Definition; Deletion: Grade 3
mfort in the prostate gland.
note; Clarification: Grade 2, 3, Definition; Deletion: Grade 5
mfort in the testis.
mfort in the uterus.

oduced by the cervical glands is discharged from the vagina naturally, especially during the childbearing years.
tching and burning in the vagina.
Deletion: Grade 5
mfort in the vagina.

ing pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery.
mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membran
into the lungs.
ge, most often by bronchial secretions and exudates.
smodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound.
of difficulty breathing.
sult from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm.
from or spreading to the larynx.
gen in the body.
accumulation of fluid in the larynx.
ular contraction of the vocal cords.
age due to mucosal edema.
ely affecting the lung parenchyma.
n the back of the nasal cavity or throat, causing sore throat and/or coughing.
ung tissues that causes a disturbance of the gas exchange that may lead to respiratory failure.
and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid.
n; Primary SOC change
air from the nose.
nd due to laryngeal or upper airway obstruction.
speed of the voice.

nd during breathing. It results from the narrowing or obstruction of the respiratory airways.
compared to normal for a given individual at a given age and body location.
lting from the growth of bacteria on the body.
are generally fine, the texture is a papery thin texture.
around a pale center).

thema and exfoliation. The inflammatory process involves > 90% of the body surface area.
rowth in women in anatomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, m
note; Clarification: Grade 3, Definition
the accepted limits of normal in a particular body region, for a particular age or race.
eous adipose tissue at the site of multiple subcutaneous injections of insulin.
3, Definition
he skin to light.
n and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a b
g of the epidermis and dermis.

excessive melanin deposition.
skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.
terized by wheals with pale interiors and well-defined red margins.
2, Definition
rary sensation of intense body warmth, flushing, sometimes accompanied by sweating upon cooling.
2, 3, 4, Definition
ssues that causes swelling.
n involving a superficial vein of the extremities.

in the superior vena cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and he
ase in the risk of hemorrhage as the body is depleted of platelets and coagulation factors.
.4 degrees F) for more than one hour
yond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds.
failure of atrial electrical impulse conduction through the atrioventricular (AV) node to the ventricles.
subjective vertigo).
s, and osteoporosis, usually due to exogenous corticosteroids.
calcium in the blood).
efore age 9 for boys.

ersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness an
days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy
and radiation. The extent of damage depends on the length and intensity of exposure and time until provision of treatment.
ory reaction is confined to the previously irradiated skin and the symptoms disappear after the removal of the pharmaceutical agent.
ea, vomiting, indigestion and headaches.
xtremities, hyperreflexia, positive Babinski and a decrease in fine motor coordination.
an increase in the stimulation of the vagus nerve.
nth week of gestation.

uma or surgery.
also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrh
companied by a distinctive sound.
all-trans retinoic acid.
d under androgen control (beard, moustache, chest, abdomen).
le color and eventually become a brownish-yellow color.

kin and the mucous membranes.
er arms, cough, orthopnea and headache.

anosis and loss of consciousness and may lead to death.
, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea.

ovision of treatment.
of the pharmaceutical agent.
neezing, nasal congestion, rhinorrhea and itching.
MedDRA CodeMedDRA SOC CTCAE Term Grade 1 Grade 2 Grade 3 Grade 4
10002272 Blood and lympAnemia Hemoglobin (Hg Hgb <10.0 - 8.0Hgb <8.0 g/dL; Life-threateni
10005329 Blood and lympBlood and lymph Asymptomatic Moderate;
or minim
Severe or medically Life-threateni
significant but not immediately
10048580 Blood and lympBone marrow hMildly hypocellModerately hypo Severely hypoce Aplastic persis
10013442 Blood and lympDisseminated i - Laboratory findLaboratory fin Life-threateni
10014950 Blood and lympEosinophilia >ULN and >Bas - Steroids initiat -
10016288 Blood and lympFebrile neutro - - ANC <1000/mm3 Life-threateni
10019491 Blood and lympHemolysis Laboratory evidEvidence of hemolysis
Transfusion and or
>=2Life-threateni
gm decrease in hemoglobin
10019515 Blood and lympHemolytic ure [Grade deleted.- Map to Hemolysis, Laboratory
Gradefind1.]Life-threateni
Evidence of RBC destruction (schisto
10024378 Blood and lympLeukocytosis - - >100,000/mm3Clinical manife
10025182 Blood and lympLymph node paMild pain Moderate pain;Severe pain; li -
10027506 Blood and lympMethemoglobi - >ULN Requiring urgeLife-threateni
10041633 Blood and lympSpleen disorde[Term deleted.[Term Map todeleted.
Blood and
-Maplymphatic
to Blood [Term
system
and lymphatic
deleted.
disorders
system
Map
- Other,
todisorders
Blood
specify
and- (Spl
Oth
lym
10043648 Blood and lympThrombotic th [Grade deleted.- Map to Hemolysis, Laboratory
Gradefind1.]Life-threateni
Evidence of RBC destruction (schisto
10051592 Cardiac disordeAcute coronar - [Term deleted.[Term
Map to deleted.
Chest pain-cardiac,
[Term
Map to deleted.
ChestGrade
pain-cardiac,
Map2.]to Myocardial
Symptomatic,
Grade 3.]inf
10061589 Cardiac disordeAortic valve di Asymptomatic Asymptomatic;
va Symptomatic; sLife-threatenin
10003586 Cardiac disordeAsystole Periods of asy - - Life-threateni
10003658 Cardiac disordeAtrial fibrillati Asymptomatic,Non-urgent med Symptomatic, and Life-threatening
incompletelyconsequences;
controlled medically
embo
10003662 Cardiac disordeAtrial flutter Asymptomatic,Non-urgent med Symptomatic and Life-threatening
incompletely consequences;
controlled medically
embo
10003673 Cardiac disordeAtrioventricul - Non-urgent intSymptomatic and Life-threateni
incompletely controlled medically
10003674 Cardiac disordeAtrioventriculaAsymptomatic,Non-urgent int - -
10007515 Cardiac disordeCardiac arrest - - - Life-threateni
10007541 Cardiac disordeCardiac disordeAsymptomatic Moderate;
or minim
10008481 Cardiac disordeChest pain - caMild pain Moderate pain;Pain painatonrest;
exertion;
limiting
- limiting
self care
instrumental
ADL; cardiac ADL;
catheteriz
hemod
10010276 Cardiac disordeConduction disMild symptoms; Moderate symptoms
SevereNon-urgent
symptoms;Life-threatening
medical
Symptomatic,
intervention
consequences;
urgent indicated
intervention
urgen
10010783 Cardiac disordeConstrictive per- - [Term deleted.[Term Map to deleted.
Pericarditis,
Map toGrade
Pericarditis,
3.] Sympt G
10011703 Cardiac disordeCyanosis - Present - -
10019279 Cardiac disordeHeart failure Asymptomatic Symptoms
wi withSevere
mild towith
moderate
sSymptoms
Life-threateni
activity
at rest
or exertion
or with minimal activ
10069501 Cardiac disordeLeft ventricula - - Symptomatic due Refractory or p
10061532 Cardiac disordeMitral valve di Asymptomatic Asymptomatic;
10027786 Cardiac disordeMobitz (type) IAsymptomatic,Symptomatic; m Symptomatic and Life-threateni
incompletely controlled medically
10027787 Cardiac disordeMobitz type I Asymptomatic,Symptomatic; m Symptomatic an Life-threateni
10028596 Cardiac disordeMyocardial inf - Asymptomatic Severe
a symptom Life-threateni
10028606 Cardiac disordeMyocarditis [Grade deleted.Symptoms Map to Cardiac
withSevere
mild
disorders
towith
moderate
symptoms
- Other,
Life-threateni
activity
specify
at rest
or(Myocarditis),
exertion
or with minimal
Gradeactivi
1.]
10033557 Cardiac disordePalpitations Mild symptoms; Intervention in - -
10034040 Cardiac disordeParoxysmal atriAsymptomatic,Symptomatic; medical IV medication
management
indicated
Life-threatenin
indicated;
Symptomatic,
Non-urgent
urgentmedica
interve
10034474 Cardiac disordePericardial eff - Asymptomatic Effusion
e with Life-threateni
10053565 Cardiac disordePericardial ta - - - Life-threateni
10034484 Cardiac disordePericarditis Asymptomatic,Symptomatic
E per
Pericarditis wi Life-threateni
10061541 Cardiac disordePulmonary valvAsymptomatic Asymptomatic;
10038748 Cardiac disordeRestrictive ca Imaging findingSymptomatic wit Symptomatic heart Refractory
failurehear
or other cardiac symptom
10058597 Cardiac disordeRight ventriculAsymptomatic Symptoms
wi withSevere
mild tosymptoms,
moderate
Life-threatenin
associated
activity or exertion
with hypoxemia, right
10040639 Cardiac disordeSick sinus syn Asymptomatic,Non-urgent intervention
Severe, medically
indicated
Life-threateni
significant;
Symptomatic,
medical
intervention
Symptomatic,
not i
10040741 Cardiac disordeSinus bradycarAsymptomatic,Symptomatic, medical Severe, medically
intervention
Life-threateni
significant,
not indicated;
medicalchange
Symptomatic,
in medic
10040752 Cardiac disordeSinus tachycar Asymptomatic,Symptomatic; nUrgent medical-
10042604 Cardiac disordeSupraventriculAsymptomatic,Non-urgent med Medical Symptomatic,Life-threatening
urgent intervention
consequences; indicated
urgen
10061389 Cardiac disordeTricuspid valveAsymptomatic Asymptomatic;
10047281 Cardiac disordeVentricular ar Asymptomatic,Non-urgent med Medical UrgentLife-threatening
intervention indicated
consequences; hemo
10047290 Cardiac disordeVentricular fibr - - - Life-threatening consequences; hemo
10047302 Cardiac disordeVentricular tac - Non-urgent med Medical Symptomatic,Life-threatening
urgent intervention
consequences; indicated
hemo
10048015 Cardiac disordeWolff-Parkins [Term deleted.[Term
Map to deleted.
Cardiac[Term
Map
disorders
to
deleted.
Cardiac
- Other,
[Term
Mapdisorders
specify
to
deleted.
Cardiac
- (Wolff-Parkinson-White
Other,
Map
disorders
specify
to Cardiac
- (Wolff-Par
Other,
disord
spes
10010331 Congenital, famCongenital, famAsymptomatic Moderate;
or minimSevere or medically Life-threateni
10013993 Ear and labyrinEar and labyrinAsymptomatic Moderate;
10014020 Ear and labyrinEar pain Mild pain Moderate pain;Severe pain; li -
10065837 Ear and labyrinExternal ear i [Term deleted.[Term
Map to deleted.
Otitis externa,
[Term
Map to deleted.
Grade
Otitis externa,
[Term
1.]
Map External
to
deleted.
Grade
Otitis
otitis
externa,
2.]
Map with
External
to erythema
Grade
Otitis otitis
externa,
3.] with
Exte
or d
10065785 Ear and labyrinExternal ear paMild pain Moderate pain;Severe pain; li -
10019245 Ear and labyrinHearing impairPediatric (on a Pediatric
1, 2, 3, 4,(on
6 a Pediatric
1, 2, 3, 4,(on
6 a Pediatric:
1, 2, 3, 4, 6Audiologic indication for co
10065838 Ear and labyrinMiddle ear inf Serous otitis Serous otitis, Mastoiditis; neLife-threateni
10043882 Ear and labyrinTinnitus Mild symptoms;Moderate sympt Severe symptom -
10047340 Ear and labyrinVertigo Mild symptom Moderate sympt Severe symptom -
10047386 Ear and labyrinVestibular diso - Symptomatic; lSevere symptom -
10001367 Endocrine disoAdrenal insuffi Asymptomatic;Moderate
c sympt Severe symptom Life-threateni
10011655 Endocrine disoCushingoid Mild symptoms;Moderate sympt Severe symptom -
10012205 Endocrine disoDelayed puber - No breast deveNo breast deve -
10014698 Endocrine disoEndocrine disorAsymptomatic Moderate;
10018746 Endocrine disoGrowth accele - >= +2 SD (stand- -
10020705 Endocrine disoHyperparathyrMild symptoms; Moderate sympt - -
10020850 Endocrine disoHyperthyroidi Asymptomatic;Symptomatic;
c tSevere symptoms Life-threateni
10021041 Endocrine disoHypoparathyroAsymptomatic;Moderate
c sympt Severe symptom Life-threateni
10062767 Endocrine disoHypophysitis Asymptomatic Moderate;
or minimSevere or medic Life-threateni
10021067 Endocrine disoHypopituitaris Asymptomatic Moderate;
or minimSevere or medic Life-threateni
10021114 Endocrine disoHypothyroidis Asymptomatic;Symptomatic;
c tSevere symptoms Life-threateni
10058084 Endocrine disoPrecocious pubPhysical signs Physical signs - -
10067734 Endocrine disoTestosterone dAsymptomatic;Replacement th- -
10047488 Endocrine disoVirilization Mild symptoms;Moderate sympt - -
10005886 Eye disorders Blurred vision Intervention noSymptomatic; moderate
Symptomatic decrease
with
Bestmarked
corrected
in visualdecrease
acuity (best
in visual
corrected
acuityv
10007739 Eye disorders Cataract Asymptomatic;Symptomatic;
c moderate
with
Blindness(Best
marked
in visualdecrease
acuity
corrected
(best
in visual
visual
corrected
acuity
acuity
v
10048492 Eye disorders Corneal ulcer - [Grade deleted.Limiting
Map toselfCorneal
care
Perforation
ADL;
ulcer,declining
Grade
or blindness
3.]vision
Symptomatic;
(worse
(20/200 than
or
medw
2
10013774 Eye disorders Dry eye Asymptomatic;Symptomatic;
clinical or diagnostic
moderate
Symptomaticobservations
decrease
with
- marked
inonly;
visual
mild
decrease
acuity
symptoms
(best
in visual
corrected
relieved
acuitybv
10015829 Eye disorders Extraocular muAsymptomatic;Unilateral
c paresis
Limiting
withoutselfdouble
care
Bilateral
ADL;
vision
disabling
pares
Symptomatic;
Bilaterallimiting
paresisinstr
or u
10015919 Eye disorders Eye disorders -Asymptomatic Moderate;
or mild symptoms;
minimal,
Severe clinical
local
or medically
orornoninvasive
Sight-threatening
diagnostic
significant
observations
intervention
butconsequences;
not immediately
only;
indicated;
interven
urge
lim
10015958 Eye disorders Eye pain Mild pain Moderate pain;Severe pain; li -
10061145 Eye disorders Eyelid functionAsymptomatic;Symptomatic;
c nLimiting self c -
10016757 Eye disorders Flashing lights Symptomatic bu Limiting instr Limiting self c -
10016778 Eye disorders Floaters Symptomatic buLimiting instr Limiting self c -
10018304 Eye disorders Glaucoma Less than 8 mmHg
EIOPofwhich
Eelevated
canEIOP
beintraocular
reduced
causing tomarked
pressure
Visual
21 mmHg field
visual
(EIOP)
or
deficit
field
under
withdeficits
within
single
with the
topical
(e.g.,
topical
central
involv
med
age1
10023332 Eye disorders Keratitis Asymptomatic;Symptomatic;
c moderate
with
Perforation;
marked
in visualdecrease
oracuity
blindness
(best
in visual
(best
corrected
acuity
correcv
10029404 Eye disorders Night blindnes Symptomatic bu Symptomatic; moderate
with
Blindness(Best
marked
in visualdecrease
acuity
corrected
(best
in visual
visual
corrected
acuity
acuity
v
10061322 Eye disorders Optic nerve di Asymptomatic;Moderate
c decrease
Limitingin visual
visionacuity
Blindness(Best
in the(best
affected
corrected
corrected
eye (worse
visualvisual
than
acuity
acuity
20/40
20
10033703 Eye disorders Papilledema Asymptomatic;Symptomatic;
no visual fieldmoderate
Symptomatic
defects deficit
decrease
with
Blindness(Best
marked
in visualdecrease
acuity
corrected
(best
in visual
visual
corrected
acuity
acuity
v
10034960 Eye disorders Photophobia Symptomatic bu Limiting instr Limiting self c -
10038848 Eye disorders Retinal detach [Grade deleted.[GradeMap todeleted.
Retinal
Macular
Map
detachment,
tosparing
RetinalMacula-off
Grade
Rrhegmatogenous
detachment,
3.] Asymptomatic
rhegmatogenous
Gradeor3.]exudative
Exudative
retinaldetan
d
10038897 Eye disorders Retinal tear No retinal det No retinal detachment [Grade deleted.
and treatment
[Grade
Map to deleted.
indicated
RetinalMapdetachment,
Laser
to Retinal
therapy Grade
detac
or pn3
10038901 Eye disorders Retinal vascula - Retinal vascularIntravitreal
disorder without
medication;
- neovascularizationTopical
operative intervention medica
indic
10038923 Eye disorders Retinopathy Asymptomatic;Symptomatic;
c with
Symptomatic
moderatewith Blindness(Best
decrease
marked in decrease
visual
corrected
acuity
in visual
(best
visualacuity
correc
acuity
10061510 Eye disorders Scleral disorde No change in vision
Symptomatic,;
from baseline
Symptomatic
moderate
Asymptomatic;
decrease
with
Blindness(Best
marked
in
clinical
visualdecrease
oracuity
corrected
diagnostic
(best
in visual
visual
corrected
observatio
acuity
acuityv
10046851 Eye disorders Uveitis Anterior uveitisAnterior
with trace
uveitis
cellsAsymptomatic;
Anterior
with 1+ uveitis
or 2+ Blindness(Best
cells;
with
clinical
medical
3+ or
orgreater
diagnostic
intervention
corrected
cells;observations
visual
intermediat
indicated
acuityo
10047516 Eye disorders Vision decreas - Moderate decrea Marked decrease Best corrected
10047656 Eye disorders Vitreous hemoIntervention not Symptomatic;
indicatedAsymptomatic
moderate
orwith
mild
Blindness(Best
marked
symptoms;
in visualdecrease
acuity
corrected
clinical
(best
inorvisual
visual
corrected
diagnostic
acuity
acuityv
10047848 Eye disorders Watering eyes Intervention noSymptomatic; moderate Operative decrease
intervention
Best corrected
in visual
indicated
acuityMarked
(best corrected
decrease vi
10054541 Eye disorders Skin
Periorbital
and subcutaneous
ed Soft or non-pitIndurated
tissue disorders or piEdema associate -
10000060 GastrointestinaAbdominal distAsymptomatic;Symptomatic;
c lSevere discomfo-
10000081 GastrointestinaAbdominal pai Mild pain Moderate pain;Severe pain; li -
10002153 GastrointestinaAnal fissure Asymptomatic Symptomatic Invasive interv -
10002156 GastrointestinaAnal fistula Asymptomatic;Symptomatic;
altered
Severelyobservations
GIaltered
function,
Life-threateni
GI function;
invasive
only; intervention
intervention
tube feeding, notnot
indicated
TPNindicat
or ho
10055226 GastrointestinaAnal hemorrhaMild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10065721 GastrointestinaAnal mucositis Asymptomatic Symptomatic;
o mSevere symptom [Grade deleted. Map to Anal Ulcer, G
10065722 GastrointestinaAnal necrosis - - TPN or hospitalization
Life-threateni
indicated; radiologic, endosco
10002167 GastrointestinaAnal pain Mild pain Moderate pain;Severe pain; li -
10002176 GastrointestinaAnal stenosis Asymptomatic;Symptomatic;
c aSymptomatic and Life-threateni
10002180 GastrointestinaAnal ulcer Asymptomatic;Symptomatic;
c aSeverely altered Life-threateni
GI function; TPN indicated; elective
10003445 GastrointestinaAscites Asymptomatic;Symptomatic;
c mSevere symptom Life-threateni
10004222 GastrointestinaBelching Increase from Intervention in - -
10005265 GastrointestinaBloating No change in bo Symptomatic, d- -
10065747 GastrointestinaCecal hemorrh Mild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10008417 GastrointestinaCheilitis Asymptomatic;Moderate
c symptSevere symptoms -
10009167 GastrointestinaChylous ascitesAsymptomatic;Symptomatic;
c me
Severe symptom Life-threateni
10009887 GastrointestinaColitis Asymptomatic;Abdominal
c painSevere abdominal Life-threateni
pain; change in bowel habits; med
10009995 GastrointestinaColonic fistula Asymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threateni
GI function;
invasive
only; intervention
intervention
bowel rest, not
TPN
not
indicated
indicat
or hosp
10009998 GastrointestinaColonic hemor Mild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10010000 GastrointestinaColonic obstru Asymptomatic;Symptomatic;
c aHospitalizationLife-threateni
indicated; elective operative invasive
10010001 GastrointestinaColonic perfora- Symptomatic; medical
Severe symptoms;
Invasive Life-threateni
intervention
elective operative
not indicated
Invasive interv
10010004 GastrointestinaColonic stenosiAsymptomatic;Symptomatic;
c aSeverely altereLife-threateni
10010006 GastrointestinaColonic ulcer Asymptomatic;Symptomatic;
10010774 GastrointestinaConstipation Occasional or iPersistent sympObstipation witLife-threateni
10012318 GastrointestinaDental caries One or more den Dental caries i Dental caries re-
10012727 GastrointestinaDiarrhea Increase of <4 Increase of 4 - 6Increase
stools per
of >=7
dayLife-threateni
stools
over baseline;
per day over
moderate
baseline;
increase
incontiin
10013781 GastrointestinaDry mouth Symptomatic (e. Moderate sympto Inability to ad -
10013828 GastrointestinaDuodenal fistu Asymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threateni
GI function;
invasive
only; intervention
intervention
tube feeding, notnot
indicated
TPNindicat
or ho
10055242 GastrointestinaDuodenal hemo Mild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10013830 GastrointestinaDuodenal obstrAsymptomatic;Symptomatic;
c aHospitalizationLife-threateni
indicated; or elective operative invas
10013832 GastrointestinaDuodenal perfo- Symptomatic; medical
Severe symptoms;
intervention
elective operative
not indicated
Invasive interv
10050094 GastrointestinaDuodenal stenoAsymptomatic;Symptomatic;
GI function; tube feeding; or hospit
10013836 GastrointestinaDuodenal ulcerAsymptomatic;Moderate
c sSymptomatics;
Severely altered
medical
Life-threateni
GI function;
intervention
TPN indicated; limiting
elective
10013946 GastrointestinaDyspepsia Mild symptoms; Moderate sympt Severe symptoms; - surgical operative intervention in
10013950 GastrointestinaDysphagia Symptomatic, ab
Symptomatic an Severely altered Life-threateni
eating/swallowing; tube feeding, or
10014893 GastrointestinaEnterocolitis Asymptomatic;Abdominal
c painSevere or persiLife-threateni
10062570 GastrointestinaEnterovesical f Asymptomatic;Symptomatic;
altered
Severe,observations
GI
medically
function,
Life-threateni
significant;
invasive
only; intervention
intervention
medical Invasive
notnot
indicated
indicat
interv
10065851 GastrointestinaEsophageal fistAsymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threateni
GI function;
invasive
only; intervention
intervention
tube feeding,
notnot
indicated
TPNindicat
or ho
10015384 GastrointestinaEsophageal he Mild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10065727 GastrointestinaEsophageal nec- - Inability to aliment
Life-threateni
adequately by GI tract; radiologic
10015387 GastrointestinaEsophageal obsAsymptomatic;Symptomatic;
c al
HospitalizationLife-threateni
10015388 GastrointestinaEsophageal paiMild pain Moderate pain;Severe pain; li -
10055472 GastrointestinaEsophageal per- Symptomatic; medical
Severe symptoms;
InvasiveLife-threateni
intervention
elective operative
not indicated
Invasive interv
10015448 GastrointestinaEsophageal steAsymptomatic;Symptomatic;
10015451 GastrointestinaEsophageal ulcAsymptomatic;Symptomatic;
c al
Severely altered Life-threateni
10015453 GastrointestinaEsophageal var - Self-limited; intervention
Transfusionnotindicated,
Life-threateni
indicated radiologic, endoscopic, or ele
10015461 GastrointestinaEsophagitis Asymptomatic;Symptomatic;
eating/swallowing; tube feeding, TP
10016296 GastrointestinaFecal incontin Occasional useDaily use of paSevere symptom -
10016766 GastrointestinaFlatulence Mild symptoms;
Moderate; pers- -
10065713 GastrointestinaGastric fistula Asymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threatening
GI function;
invasive
only; intervention
intervention
bowel
consequences;
rest;
not
tube
not
indicated
indicat
feedin
urgen
10017789 GastrointestinaGastric hemor Mild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10051886 GastrointestinaGastric necrosi - - Inability to aliment
Life-threateni
10017815 GastrointestinaGastric perfora - Symptomatic; medical
Severe symptoms;
intervention
elective operative
not indicated
Invasive interv
10061970 GastrointestinaGastric stenosiAsymptomatic;Symptomatic;
10017822 GastrointestinaGastric ulcer Asymptomatic;Symptomatic;
c al
10017853 GastrointestinaGastritis Asymptomatic;Symptomatic;
c al
Severely altereLife-threateni
10066874 GastrointestinaGastroesophage Mild symptoms;
Moderate sympt Severe symptoms; - surgical operative intervention in
10017947 GastrointestinaGastrointestinaAsymptomatic Moderate;
or minim
Severe or medically
Life-threateni
10017877 GastrointestinaGastrointestinalAsymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threatening
GI function;
invasive
only; intervention
intervention
tube
consequences;
feeding,
notnot
indicated
TPNindicat
urgen
or ho
10017999 GastrointestinaGastrointestinaMild pain Moderate pain;Severe pain; li -
10018043 GastrointestinaGastroparesis Mild nausea, eaModerate sympt Weight loss >=20%Life-threateni
from baseline; tube feeding or TP
10018286 GastrointestinaGingival pain Mild pain Moderate painSeverei pain; ina-
10060640 GastrointestinaHemorrhoidal Mild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10019611 GastrointestinaHemorrhoids Asymptomatic;Symptomatic;
c bSevere symptoms; - radiologic, endoscopic or elective
10065728 GastrointestinaIleal fistula Asymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threateni
GI function;
invasive
only; intervention
intervention
TPN or hospitalization
notnot
indicated
indicati
10055287 GastrointestinaIleal hemorrha Mild symptoms;Moderate
intervention
symptoms;
Transfusion
not indicated
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10065730 GastrointestinaIleal obstructi Asymptomatic;Symptomatic;
c altered
Hospitalization
GI function;
Life-threateni
indicated;
limitingelective
instrumental
operative
ADL;invasive
naso-
10021305 GastrointestinaIleal perforatio - Symptomatic; medical
Severe symptoms;
intervention
elective operative
not indicated
Invasive interv
10021307 GastrointestinaIleal stenosis Asymptomatic;Symptomatic;
10021309 GastrointestinaIleal ulcer Asymptomatic;Symptomatic;
10021328 GastrointestinaIleus Asymptomatic Symptomatic;
a al
GI function; TPN indicated; tube pla
10055291 GastrointestinaIntra-abdomin - Moderate symptoms;Transfusion
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10065719 GastrointestinaJejunal fistula Asymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threateni
GI function;
invasive
only; intervention
intervention
notnot
indicated
indicati
10055300 GastrointestinaJejunal hemor Mild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medical
indicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10065732 GastrointestinaJejunal obstrucAsymptomatic;Symptomatic;
c al
10023174 GastrointestinaJejunal perfora - Symptomatic; medical
Severe symptoms;
intervention
elective operative
not indicated
Invasive interv
10023176 GastrointestinaJejunal stenosiAsymptomatic;Symptomatic;
10023177 GastrointestinaJejunal ulcer Asymptomatic;Symptomatic;
10024561 GastrointestinaLip pain Mild pain Moderate pain;Severe pain; li -
10051746 GastrointestinaLower gastroinMild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medicalindicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10025476 GastrointestinaMalabsorption - Altered diet; o Inability to al Life-threateni
10028130 GastrointestinaMucositis oral Asymptomatic Moderate
o painSevere
or ulcerpain;
thatinLife-threateni
does; not interfereing with oral intake
10028813 GastrointestinaNausea Loss of appetitOral intake decInadequate oral-
10029957 GastrointestinaObstruction gasAsymptomatic;Symptomatic;
c al
10065720 GastrointestinaOral cavity fist Asymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threateni
GI function;
invasive
only; intervention
intervention
notnot
indicated
indicati
10054520 GastrointestinaOral dysesthesMild discomfortModerate pain;Disabling pain; -
10030980 GastrointestinaOral hemorrhaMild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medicalindicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10031009 GastrointestinaOral pain Mild pain Moderate pain;Severe pain; li -
10065703 GastrointestinaPancreatic ductAsymptomatic;Symptomatic;
10049192 GastrointestinaPancreatic fist Asymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threatening
GI function;
invasive
only; intervention
intervention
tube
consequences;
feeding
notnot
or
indicated
TPN
indicat
urgen
or
10033626 GastrointestinaPancreatic he Mild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medicalindicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10058096 GastrointestinaPancreatic necr- - Tube feeding orLife-threateni
TPN indicated; radiologic, endoscop
10033645 GastrointestinaPancreatitis - Enzyme elevation; Severe
or radiologic
pain; voLife-threateni
findings only
10034536 GastrointestinaPeriodontal di Gingival recessModerate gingiv Spontaneous ble -
10065704 GastrointestinaPeritoneal necr- - Tube feeding orLife-threateni
10036774 GastrointestinaProctitis Rectal discomfoSymptomatics (e.g.,Severerectal
symptoms
discomfort,
Life-threateni
passing blood or mucus); me
10064993 GastrointestinaRectal fissure Asymptomatic Symptomatic Invasive interv -
10038062 GastrointestinaRectal fistula Asymptomatic;Symptomatic;
altered
GIaltered
function,
Life-threateni
GI function;
invasive
only; intervention
intervention
notnot
indicated
indicati
10038064 GastrointestinaRectal hemorr Mild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
medicalindicated,
Life-threateni
intervention
radiologic,
or minor
endoscopic,
cauterization
or elei
10063190 GastrointestinaRectal mucositiAsymptomatic Symptomatic;
o mSevere symptom Life-threateni
10065709 GastrointestinaRectal necrosis - - Tube feeding orLife-threateni
10065707 GastrointestinaRectal obstructAsymptomatic;Symptomatic;
c al
10038072 GastrointestinaRectal pain Mild pain Moderate pain;Severe pain; li -
10038073 GastrointestinaRectal perforat - Symptomatic; medical
Severe symptoms;
intervention
elective operative
not indicated
Invasive interv
10038079 GastrointestinaRectal stenosisAsymptomatic;Symptomatic;
10038080 GastrointestinaRectal ulcer Asymptomatic;Symptomatic;
c altered
SeverelyGIaltered
function
Life-threateni
GI (e.g.,
function;
altered
TPNdietary
indicated;
habits,
elective
vomi
10038981 GastrointestinaRetroperitone - Self-limited; intervention
Transfusionindicated
indicated;
Life-threateni
medical, radiologic, endoscop
10056681 GastrointestinaSalivary duct Slightly thickenThick, ropy, st Acute salivary gland Life-threateni
necrosis; severe secretion-induc
10039411 GastrointestinaSalivary gland fAsymptomatic;Symptomatic,;
Severely
alteredobservations
GIaltered
function;
Life-threatening
GI function;
tube
only; feeding
intervention
hospitalization
consequences;
invasive
notinterventi
indicated
indicate
urgen
10065710 GastrointestinaSmall intestinaAsymptomatic Symptomatic;
o mSevere pain; inLife-threateni
10041101 GastrointestinaSmall intestinaAsymptomatic;Symptomatic;
c al
10041103 GastrointestinaSmall intestina - Symptomatic; medical
Severe symptoms;
intervention
elective operative
not indicated
Invasive interv
10062263 GastrointestinaSmall intestinaAsymptomatic;Symptomatic;
c aSymptomatic and Life-threateni
10041133 GastrointestinaSmall intestineAsymptomatic;Symptomatic;
c al
10042112 GastrointestinaStomach pain Mild pain Moderate pain;Severe pain; li -
10044030 GastrointestinaTooth develop Asymptomatic;Impairment corMaldevelopment - with impairment not surgically cor
10044031 GastrointestinaTooth discolor Surface stains - - -
10044055 GastrointestinaToothache Mild pain Moderate pain;Severe pain; li -
10045271 GastrointestinaTyphlitis - - Symptomatic (e. Life-threateni
10055356 GastrointestinaUpper gastroinMild symptoms; Moderate
intervention
Outpatient symptoms;
Transfusion
not indicated
IV hydration; medicalindicated,
Life-threateni
medical intervention
radiologic,
intervention or minor
endoscopic,
cauterization
indicated or elei
10047700 GastrointestinaVomiting 1 - 2 episodes (separated
3 - 5 episodes
by 5(separated
>=6
minutes)
episodesin
by24(separated
5Life-threatening
minutes)
hrs Intervention
by
in 24
5 minutes)
hrs
consequences;
not indicated
in 24 hrs;
urgen
tTu
10054692 GastrointestinalVisceral
disorders
arteri
Vascular
- disordersBrief (<24 hrs Prolonged (>=2Life-threateni
10008531 General disordeChills Mild sensation Moderate tremo Severe or prolo-
10011912 General disordeDeath neonata - - - Neonatal loss of
10011914 General disordeDeath NOS - - - -
10061818 General disordeDisease progre - - - -
10014222 General disordeEdema face Localized faci Moderate localSevere swelling-
10050068 General disordeEdema limbs 5 - 10% inter-l >10 - 30% inter>30% inter-limb-
10058720 General disordeEdema trunk Swelling or obsReadily apparen Gross deviation-
10016059 General disordeFacial pain Mild pain Moderate pain;Severe pain; li -
10016256 General disordeFatigue Fatigue relieveFatigue not relFatigue not rel -
10016558 General disordeFever 38.0 - 39.0 deg>39.0 - 40.0 de>40.0 degrees C >40.0 degrees C
10016791 General disordeFlu like sympt Mild flu-like Moderate sympt Severe symptom -
10017577 General disordeGait disturban Mild change inModerate change Disabling; lLimiting- self care ADL
10018065 General disordeGeneral disordeAsymptomatic Moderate;
or minim
Severe or medically
Life-threateni
10018112 General disordeGeneralized e Noted on exam; Interfering wit Interferes withLife-threateni
10021113 General disordeHypothermia - 35 - >32 degree32 - >28 degree<=28 degrees C;
10064774 General disordeInfusion site e Painless edem Erythema with Ulceration
a or nLife-threateni
10022095 General disordeInjection site r Tenderness witPain; lipodystr Ulceration or nLife-threateni
10062466 General disordeLocalized ede Localized to deModerate localSevere localize -
10025482 General disordeMalaise Uneasiness or lUneasiness or lackUneasiness
of well being;
or l - limiting instrumental ADL
10028154 General disordeMulti-organ fai - - Shock with azotLife-threatenin
10054482 General disordeNeck edema Asymptomatic Moderate neckGeneralized nec Vascular or res
10062501 General disordeNon-cardiac chMild pain Moderate pain;Severe pain; li -
10033371 General disordePain Mild pain Moderate pain;Severe pain; li -
10042435 General disordeSudden death - - - -
10069480 General disordeVaccination si Local lymph n Localized ulce - -
10051341 Hepatobiliary dBile duct stenoAsymptomatic;Symptomatic;
c al
GI function; radiologic, endoscopic
10004665 Hepatobiliary dBiliary fistula - Symptomatic, invasive
Severelyand
altered
intervention
Life-threatening
GI function;
not TPN
indicated
consequences;
indicated; endosco
urgen
10006537 Hepatobiliary dBudd-Chiari s - Medical managSevere or medic Life-threateni
10008612 Hepatobiliary dCholecystitis - Symptomatic; m Severe symptoms; Life-threateni
radiologic, endoscopic or elective
10017631 Hepatobiliary dGallbladder fis Asymptomatic;Symptomatic,
invasive
Symptomatic;
observations
and intervention
or
Life-threatening
severely
only; not
intervention
altered
indicated
consequences;
GI function;
not indicated
TPN
urgen
in
10059446 Hepatobiliary dGallbladder nec- - - Life-threatening consequences; urgen
10017636 Hepatobiliary dGallbladder obAsymptomatic;Symptomatic;
c al
Symptomatic and Life-threateni
10017638 Hepatobiliary dGallbladder paMild pain Moderate pain;Severe pain; li -
10017639 Hepatobiliary dGallbladder pe - - - Life-threateni
10019663 Hepatobiliary dHepatic failure - - Asterixis; mild encephalopathy;
drug-induced liver
Mmo in
10019678 Hepatobiliary dHepatic hemorMild symptoms; Moderate
intervention
symptoms;
Transfusion
not indicated
Symptomatic;
indicated;
Life-threateni
medical
invasiveintervention
interventionindicated
indicate
10019692 Hepatobiliary dHepatic necros - - - Life-threatening consequences; urgen
10019705 Hepatobiliary dHepatic pain Mild pain Moderate pain;Severe pain; li -
10019805 Hepatobiliary dHepatobiliary dAsymptomatic Moderate;
or minim
Severe or medically
Life-threateni
10034405 Hepatobiliary dPerforation bil - - Radiologic, endoscopic
Life-threateni
or elective operative Invasive
10036200 Hepatobiliary dPortal hyperte - Decreased portReversal/retrogLife-threateni
10036206 Hepatobiliary dPortal vein th - Intervention noMedical interv Life-threateni
10063675 Hepatobiliary dSinusoidal obs - Blood bilirubinBlood bilirubinLife-threatenin
10001718 Immune system Allergic reacti Transient flushing
Intervention
or rash, drug
orProlonged
infusion
fever <38
interruption
(e.g.,
degrees
Life-threateni
not rapidly
C indicated;
(<100.4
responsive
degrees
responds
to
F);Systemic
symptoma
promptlyi
10002218 Immune system Anaphylaxis - - Symptomatic brLife-threateni
10061664 Immune system Autoimmune diAsymptomatic;Evidence of autAutoimmune reac Life-threateni
10052015 Immune system Cytokine relea Mild reaction; infusion
Therapy interruption
or infusion
Prolonged
interruption
not indicated;
(e.g.,Life-threatening
not
indicated
rapidly
intervention
responsive
but consequences;
responds
not indicated
to promptly
symptoma
press
Fevet
10021428 Immune system Immune system Asymptomatic Moderate;
or minim
Severe or medically
Life-threateni
10040400 Immune system Serum sicknessAsymptomatic;Moderate
c arthra
Severe arthralgiLife-threatenin
10056519 Infections and Abdominal infe- Oral interventioIV antibiotic, antifungal,
Life-threateni
or antiviral intervention ind
10061640 Infections and Anorectal infecLocalized;, localOral
intervention
intervention
indicated
IV antibiotic,
indicated (e.g.,
antifungal,
Life-threateni
antibiotic,
or antiviral
antifungal,
intervention
or antiviral)
ind
10003011 Infections and Appendicitis - - IV antibiotic, antifungal,
Life-threateni
10003012 Infections and Appendicitis p - [Grade deleted.Severe
Map tosymptoms;
Infections
Life-threateni
elective
and infestations
Medical intervention
- Other, specify
ind
10065744 Infections and Arteritis infect - - IV antibiotic, antifungal,
Life-threateni
10003999 Infections and Bacteremia - Blood culture - -
10061695 Infections and Biliary tract in - Oral interventioIV antibiotic, antifungal,
Life-threateni
10005047 Infections and Bladder infecti - Oral intervention IV antibiotic,
indicated (e.g.,
antifungal,
Life-threateni
antibiotic,
or antiviral
antifungal,
intervention
or antiviral)
ind
10061017 Infections and Bone infection - Oral interventioIV antibiotic, antifungal,
Life-threateni
10006259 Infections and Breast infectio - Local infection IV with
antibiotic,
moderate antifungal,
Life-threateni
symptoms; or antiviral
oral intervention
intervention
indicate
ind
10055078 Infections and Bronchial infec - Moderate symptoms;IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10007810 Infections and Catheter relate - Localized; localIVintervention
antibiotic, antifungal,
indicated;
Life-threateni
oral
or antiviral
intervention
intervention
indicated
ind(
10065761 Infections and Cecal infection - Localized; oral IV antibiotic, antifungal,
Life-threateni
10008330 Infections and Cervicitis infec - Localized; localIV antibiotic, antifungal,
Life-threateni
10010742 Infections and Conjunctivitis i - Localized; localIV antibiotic, antifungal,
Life-threateni
10061788 Infections and Corneal infecti - Localized; localIV antibiotic, antifungal,
Life-threateni
10065765 Infections and Cranial nerve i - - IV antibiotic, antifungal,
Life-threateni
10058666 Infections and Cytomegalovirus Asymptomatic Moderate
or symptSevere or medic Life-threatenin
10064687 Infections and Device related - Oral interventioIV antibiotic, antifungal,
Life-threateni
10065752 Infections and Duodenal infec - Moderate sympto IV antibiotic, antifungal,
Life-threateni
10014594 Infections and Encephalitis in - - IV antibiotic, Life-threateni
10014621 Infections and Encephalomyeli- - IV antibiotic, antifungal,
Life-threateni
10014678 Infections and Endocarditis in - - IV antibiotic, antifungal,
Life-threateni
10014801 Infections and Endophthalmiti- Local interventSystemic intervention;
Blindness(Best
or hospitalization
corrected visual
indicated
acuity
10058838 Infections and Enterocolitis i - Passage of >3 unformed
IV antibiotic,
stools
antifungal,
Life-threateni
per 24 hrs
or or
antiviral
duration
intervention
of illness >48
ind
10015109 Infections and Epstein-Barr viAsymptomatic Moderate
or symptSevere or medic Life-threateni
10058804 Infections and Esophageal inf - Local interventiIV antibiotic, antifungal,
Life-threateni
10015929 Infections and Eye infection - Localized; localIV antibiotic, antifungal,
Life-threateni
10016936 Infections and Folliculitis Covering <10%Covering 10-30% >30% BSA; syst -
10017544 Infections and Fungemia - Moderate sympt Severe or medic-
10062632 Infections and Gallbladder inf - Oral interventioIV antibiotic, antifungal,
Life-threateni
10018784 Infections and Gum infection Local therapy Moderate symptoms; IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10056522 Infections and Hepatic infecti - Moderate sympto IV antibiotic, antifungal,
Life-threateni
10058827 Infections and Hepatitis B reaAsymptomatic Moderate
10019799 Infections and Hepatitis viral Asymptomatic,Moderate
intervention
sympt
treatment
Symptomaticnot liver
indicated
Life-threatening
dysfunction; consequences;
fibrosis by biopsy;
sever
co
10080137 Infections and Herpes simplexAsymptomatic Moderate
10021881 Infections and Infections and Asymptomatic Moderate;
or minim
Severe or medically
Life-threateni
10021918 Infections and Infective myosi - Localized; localIV antibiotic, antifungal,
Life-threateni
10023216 Infections and Joint infection - Localized; localArthroscopic
intervention inLife-threateni
indicated; oral intervention indicated (
10023424 Infections and Kidney infectio - Oral interventioIV antibiotic, antifungal,
Life-threateni
10023874 Infections and Laryngitis - Moderate symptoms;IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10065755 Infections and Lip infection Localized, loca Oral intervention IV antibiotic,
indicated (e.g.,
antifungal,
- antibiotic,
or antiviral
antifungal,
intervention
or antiviral)
ind
10061229 Infections and Lung infection - Moderate symptoms;IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10050823 Infections and Lymph gland in - Localized; localIVoral
antibiotic,
intervention
antifungal,
Life-threateni
indicatedor antiviral
(e.g., topical
intervention
antibiotic,
inda
10057483 Infections and Mediastinal inf - - IV antibiotic, antifungal,
Life-threateni
10027199 Infections and Meningitis - - IV antibiotic, antifungal,
Life-threateni
10065764 Infections and Mucosal infectLocalized, loca Oral intervention IV antibiotic,
indicated (e.g.,
antifungal,
Life-threateni
antibiotic,
or antiviral
antifungal,
intervention
or antiviral)
ind
10061304 Infections and Nail infection Localized, loca Oral intervention IV antibiotic,
indicated (e.g.,
antifungal,
- antibiotic,
or antiviral
antifungal,
intervention
or antiviral)
ind
10033072 Infections and Otitis externa Localized, loca [v4.03 Grade 2IV deleted.
antibiotic,
Mapantifungal,
to
Life-threateni
grade 1or Otitis
antiviral
externa,
intervention
Grade 1.]indLo
10033078 Infections and Otitis media - Localized; localIVoral
antibiotic,
intervention
antifungal,
Life-threateni
(e.g., topical
intervention
antibiotic,
inda
10055005 Infections and Ovarian infecti - Localized; localIVoral
antibiotic,
intervention
antifungal,
Life-threateni
(e.g., topical
intervention
antibiotic,
inda
10051741 Infections and Pancreas infec - - IV antibiotic, antifungal,
Life-threateni
10069138 Infections and PapulopustularPapules and/orPapules and/orPapules pustulesand/or
covering
Papules
pustules
10-30%
and/or
covering
BSA,pustules
which
>30%may
covering
BSA,orwhich
may
anynm
10034016 Infections and Paronychia Nail fold edemaLocalized intervention Surgical indicated;
Operative- oral
intervention
intervention
indicated;
indicated
or IV
(e.g.,
antiba
10058674 Infections and Pelvic infection - Moderate symptoms;
IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10061912 Infections and Penile infectio Localized, loca [v4.03 Grade 2IV deleted.
antibiotic,
Mapantifungal,
to
Life-threateni
grade 1or Penile
antiviral
infection,
intervention
Grade 1.]
ind
10051472 Infections and Periorbital infe - Localized; localIV antibiotic, antifungal,
Life-threateni
10065766 Infections and Peripheral nerv- Localized; localIV antibiotic, antifungal,
Life-threateni
10057262 Infections and Peritoneal infe - - IV antibiotic, antifungal,
Life-threateni
10034835 Infections and Pharyngitis - Localized; localIVOral
antibiotic,
intervention
antifungal,
Life-threateni
indicated
or antiviral
(e.g., topical
intervention
antibiotic,
ind
10056627 Infections and Phlebitis infectLocalized, loca [v4.03 Grade 2IV deleted.
antibiotic,
Mapantifungal,
to
Life-threateni
grade 1or Phlebitis
antiviralinfective,
intervention
Gradeind1
10061351 Infections and Pleural infecti - Localized; localOral
IV antibiotic,
intervention
antifungal,
Life-threateni
(e.g., topical
intervention
antibiotic,
inda
10050662 Infections and Prostate infect - Moderate symptoms;
IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10037888 Infections and Rash pustular - Localized; localIV antibiotic, antifungal,
- or antiviral intervention ind
10059827 Infections and Rhinitis infecti - Localized; local -intervention indicated
- (e.g., topical antibiotic, antifu
10039413 Infections and Salivary gland - Moderate symptoms;
IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10062156 Infections and Scrotal infecti Localized, loca [v4.03 Grade 2IV deleted.
antibiotic,
Mapantifungal,
to
Life-threateni
grade 1or Scrotal
antiviral
infection,
intervention
Gradeind1.]
10040047 Infections and Sepsis - - Blood culture Life-threateni
10040555 Infections and Shingles Localized, loca Local infectio Severe or medic Life-threateni
10040753 Infections and Sinusitis - Localized; localIVoral
antibiotic,
intervention
antifungal,
Life-threateni
(e.g., topical
intervention
antibiotic,
inda
10040872 Infections and Skin infection Localized, loca Oral intervention IV antibiotic,
indicated (e.g.,
antifungal,
Life-threateni
antibiotic,
or antiviral
antifungal,
intervention
or antiviral)
ind
10065771 Infections and Small intestine - Moderate symptoms;
IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10062255 Infections and Soft tissue infe - Localized; localIVoral
antibiotic,
intervention
antifungal,
Life-threateni
(e.g., topical
intervention
antibiotic,
inda
10062112 Infections and Splenic infecti - - IV antibiotic, antifungal,
Life-threateni
10064505 Infections and Stoma site infeLocalized, loca Oral intervention IV antibiotic,
indicated (e.g.,
antifungal,
Life-threateni
antibiotic,
or antiviral
antifungal,
intervention
or antiviral)
ind
10043649 Infections and Thrush Asymptomatic;Oral interventiIV antifungal i -
10048762 Infections and Tooth infectio - Localized; localIV antibiotic, antifungal,
Life-threateni
10044302 Infections and Tracheitis - Moderate symptoms;
IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10046300 Infections and Upper respirato- Moderate symptoms;
IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10052298 Infections and Urethral infect - Localized; localIVoral
antibiotic,
intervention
antifungal,
Life-threateni
(e.g., topical
intervention
antibiotic,
inda
10046571 Infections and Urinary tract i - Localized; localIVoral
antibiotic,
intervention
antifungal,
Life-threateni
(e.g., topical
intervention
antibiotic,
inda
10062233 Infections and Uterine infecti - Moderate symptoms;
IV antibiotic,
oral intervention
antifungal,
Life-threateni
or
indicated
antiviral(e.g.,
intervention
antibiotic,
inda
10046914 Infections and Vaginal infecti Localized, loca [v4.03 Grade 2IV deleted.
antibiotic,
Mapantifungal,
to
Life-threateni
grade 1or Vaginal
antiviral
infection,
intervention
Gradeind1.]
10054688 Infections and Viremia - Moderate sympt Severe or medic-
10065772 Infections and Vulval infectio Localized, loca Oral interventionIV antibiotic,
indicated (e.g.,
antifungal,
Life-threateni
antibiotic,
or antiviral
antifungal,
intervention
or antiviral)
ind
10048038 Infections and Wound infecti Localized, loca [v4.03 Grade 2IV deleted.
antibiotic,
Mapantifungal,
to
Life-threateni
grade 1or Wound
antiviral
infection,
intervention
Gradeind1.]
10010741 Infections and Conjunctivitis
infestations EyeAsymptomatic
disorders Symptomatic;
o moderate
with
Bestmarked
corrected
in visualdecrease
acuity (best
in visual
corrected
acuityv
10028524 Infections and Myelitis
infestations Nervous
Asymptomatic;
system disorders
Moderate
m weaknSevere weakness Life-threateni
10002544 Injury, poisoni Ankle fracture Mild; non-surgicaloperative
Limiting instrumental
intervention
LimitingADL;
selfindicated
outpatient
care- ADL; elective
operativesurgery
intervention
operative indica
int
10002899 Injury, poisoni Aortic injury - Operative interSevere symptoms; Life-threateni
limiting self care ADL; disabling; r
10003162 Injury, poisoni Arterial injury Asymptomatic Symptomatic
di (e.g.,
Severeclaudication);
symptoms; Life-threateni
repair
limitingorself
revision
care ADL;
not indicated
disabling; r
10050458 Injury, poisoni Biliary anastomAsymptomatic Symptomatic;
diagnostic findingobservations
m
Severe symptoms; Life-threateni
only;
radiologic,
intervention
endoscopic
not indicated
or elective
10065802 Injury, poisoni Bladder anastoAsymptomatic Symptomatic;
m
only;
radiologic,
intervention
endoscopic
not indicated
or elective
10006504 Injury, poisoni Bruising Localized or in Generalized - -
10006634 Injury, poisoni Burn Minimal sympto Medical interv Moderate to ma Life-threateni
10061103 Injury, poisoni Dermatitis radiFaint erythemaModerate to brMoist desquama Life-threatenin
10065961 Injury, poisoni Esophageal anaAsymptomatic Symptomatic;
m
only;
radiologic,
intervention
endoscopic
not indicated
or elective
10016173 Injury, poisoni Fall Minor with no Sr ymptomatic; nHospitalization -indicated; invasive intervention indic
10065788 Injury, poisoni Fallopian tube Asymptomatic;Symptomatic;
c m
10065790 Injury, poisoni Fallopian tube [Grade deleted.Symptomatic
Map to Injury,
and
Severe
poisoning
Invasive
symptoms;
and
intervention
Life-threatenin
procedural
electivenotoperative
complications
indicatedInvasive- Other,
intervsp
10017076 Injury, poisoni Fracture Asymptomatic;Symptomatic
c bu
displaced or open wound with bo
10065893 Injury, poisoni Gastric anasto Asymptomatic Symptomatic;
m
only;
radiologic,
intervention
endoscopic
not indicated
or elective
10065879 Injury, poisoni GastrointestinaAsymptomatic Symptomatic;
m
only;
radiologic,
intervention
endoscopic
not indicated
or elective
10065712 Injury, poisoni Gastrointestina- Superficial nec Severe symptoms; Life-threateni
hospitalization indicated;or electi
10020100 Injury, poisoni Hip fracture - Hairline fracture;
Severe
mild pain;
pain; holimiting
Life-threateni
instrumental ADL; non-surgical
10022161 Injury, poisoni Injury to caroti - Repair or revis Severe symptoms Life-threateni
10022213 Injury, poisoni Injury to infer Asymptomatic Symptomatic;
di re
Severe symptoms Life-threateni
10065849 Injury, poisoni Injury to jugula - Repair or revis Symptomatic limitingLife-threateni
self care ADL; disabling; repair
10022356 Injury, poisoni Injury to superAsymptomatic Symptomatic;
di re
Severe symptoms; Life-threatening
limiting self care
consequences;
ADL; disabling;
evider
10022117 Injury, poisoni Injury, poisoni Asymptomatic Moderate;
or minimSevere or medicallyLife-threateni
10059095 Injury, poisoni Intestinal stomAsymptomatic Symptomatic;
m
only;
radiologic,
intervention
endoscopic
not indicated
or elective
10059094 Injury, poisoni Intestinal stom - Self-limited; i Severe symptoms Life-threateni
10049468 Injury, poisoni Intestinal stomMinimal bleedin Moderate bleed Severe bleeding; Life-threateni
tTransfusion indicated; radiologic o
10065826 Injury, poisoni Intraoperative Parimary repair Partial resecti Complete resection Life-threateni
or reconstruction of injured orga
10065831 Injury, poisoni Intraoperative Primary repair Partial resecti Complete resection Life-threateni
10065843 Injury, poisoni Intraoperative - - Primary repair Life-threateni
10055298 Injury, poisoni Intraoperative - - Postoperative radiologic,
Life-threateniendoscopic, or operative in
10065846 Injury, poisoni Intraoperative [Term deleted.[Term
Map to deleted.
Injury,[Term
poisoning
Map to deleted.
Injury,
and[Term
procedural
poisoning
Map to deleted.
Injury,
and
complications
procedural
poisoning
Map to Injury,
and
-complicati
Other,
proced
poisoni
spe
10065847 Injury, poisoni Intraoperative - Primary repair Resection or reconstruction
Life-threateniof injured organ/structu
10065803 Injury, poisoni Kidney anastom Asymptomatic Symptomatic;
m
only;
radiologic,
intervention
endoscopic
not indicated
or elective
10065891 Injury, poisoni Large intestinaAsymptomatic Symptomatic;
mSevere symptoms; Life-threateni
only;radiologic,
intervention
endoscopic
not indicated
or elective
10050457 Injury, poisoni Pancreatic anaAsymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10065705 Injury, poisoni Pharyngeal anaAsymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10055322 Injury, poisoni Postoperative Mild symptoms; Moderate
Minimal bleeding Transfusion
requiring
identifiedindicated
transfusion
Life-threateni
on clinicalof >=2
exam;
< 2units
units
intervention
(10
(10cc/kg
cc/kgfor
for
not pedi
ped
ind
10056745 Injury, poisoni Postoperative - Extubated withiExtubated >72 Life-threatenin
10065745 Injury, poisoni Prolapse of int Asymptomatic;Recurrent afterSevere symptoms Life-threateni
10065822 Injury, poisoni Prolapse of ur Asymptomatic;Local
c care or mDysfunctional sLife-threateni
10037767 Injury, poisoni Radiation recalFaint erythemaModerate to brMoist desquama Life-threatenin
10065894 Injury, poisoni Rectal anastomAsymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10040102 Injury, poisoni Seroma Asymptomatic;Symptomatic;
c sSymptomatic, elective - radiologic or operative invasiv
10065892 Injury, poisoni Small intestina Asymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10065897 Injury, poisoni Spermatic cordAsymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10041569 Injury, poisoni Spinal fractureMild back pain;Moderate backSevere p back pain Life-threateni
10065898 Injury, poisoni Stenosis of gas - Symptomatic; IV Severely altereLife-threateni
10042127 Injury, poisoni Stomal ulcer Asymptomatic;Symptomatic;
c mSevere symptom -
10062548 Injury, poisoni Tracheal hemoMild symptoms; Moderate
Minimal symptomsbleeding;
bleeding
Severe identified
bleeding; Life-threateni
onmedical
tTransfusion
clinicalintervention
or diagnostic
indicated; indicated
exam;
radiologic
intervo
10044291 Injury, poisoni Tracheal obstr Partial asymptoSymptomatic (e. Stridor or respiratoryLife-threatenin
distress limting self care ADL; r
10065749 Injury, poisoni Tracheostomy M s inimal bleedin
Moderate bleed Severe bleeding; Life-threateni
10065814 Injury, poisoni Ureteric anast Asymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10065815 Injury, poisoni Urethral anast Asymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10065882 Injury, poisoni Urostomy leak Asymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10065883 Injury, poisoni Urostomy obstAsymptomatic;Symptomatic;
dAlteredobservations
organ fLife-threatenin
only; intervention not indicated
10065748 Injury, poisoni Urostomy site Minimal bleedin Moderate bleed Severe bleeding; Life-threateni
10065885 Injury, poisoni Urostomy steno- Symptomatic but Symptomatic
no hydronephrosis,
(e.
Life-threateni
no sepsis, or no renal dysfunc
10065886 Injury, poisoni Uterine anastoAsymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10046810 Injury, poisoni Uterine perfor [Grade deleted.Symptomatic
Map to Injury, and
Severe
poisoning
Invasive
symptoms;
and
intervention
Life-threateni
procedural
electivenotoperative
complications
indicatedInvasive - Other,
interv
sp
10046861 Injury, poisoni Vaccination coMild pain; erytModerate pain;Severe pain; ErLife-threateni
10065887 Injury, poisoni Vaginal anasto Asymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10065888 Injury, poisoni Vas deferens a Asymptomatic Symptomatic;
only;radiologic,
intervention
endoscopic
not indicated
or elective
10062169 Injury, poisoni Vascular acces TPA administratDevice dislodg Pulmonary embolism, Life-threatening
dDeep vein consequences
or cardiac thromb
with h
10047228 Injury, poisoni Venous injury Asymptomatic Symptomatic
di (e.
limiting self care ADL; disabling; r
10053692 Injury, poisoni Wound complicIncisional separation
Incisional
of <=25%
separation
Hernia
of wound,
>25%
withoutno
of Life-threatening
wound;
deeper
evidence than
Bedside
of strangulation;
superficial
consequences
local care fascia
indicated
fascial
Observ
Hernia
dis
10048031 Injury, poisoni Wound dehisc Incisional separation,
Incisionalintervention
separation,
Fascial notlocal
disruption
indicated
careLife-threatenin
(e.g.,
orofdehiscence
<=25%
suturing)of wound,
or
without
medical
no
evisceration
deeper
interventith
10048049 Injury, poisoni Wrist fracture Mild; non-surgicaloperative
Limiting instrumental
intervention
LimitingADL; selfindicated
outpatient
care- ADL; elective
operative surgery
intervention
operative indica
int
10051792 Injury, poisoning
Infusion
and procedural
relateMildcomplications
transient Therapy
Generalor infu
disorders
Prolonged and (e.g.
administration
Life-threateni site conditions
10000636 Investigations Activated part >ULN - 1.5 x U >1.5 - 2.5 x UL >2.5 x ULN; hemorrhage - bleeding
10001551 Investigations Alanine aminot>ULN - 3.0 x ULN >3.0if baseline
- 5.0 x ULNwas>5.0
if normal;
baseline
- 20.0 x1.5was
ULN>20.0
- 3.0
normal;
if baseline
xxbaseline
ULN>3.0
ifwas
baseline
-if5.0
baseline
normal;
x baseline
was>5.0
was
normal;
ifabnor
- 20.0
base>
10001675 Investigations Alkaline phosp >ULN - 2.5 x ULN >2.5if baseline
- 5.0 x ULNwas>5.0
if normal;
baseline
- 20.0 x2.0was
ULN>20.0
- 2.5
normal;
if baseline
xxbaseline
ULN>2.5
ifwas
baseline
-if5.0
baseline
normal;
x baseline
was>5.0
was
normal;
ifabnor
- 20.0
base>
10003481 Investigations Aspartate amin>ULN - 3.0 x ULN >3.0if baseline
- 5.0 x ULNwas>5.0
if normal;
baseline
- 20.0 x1.5was
ULN>20.0
- 3.0
normal;
if baseline
xxbaseline
ULN>3.0
ifwas
baseline
-if5.0
baseline
normal;
x baseline
was>5.0
was
normal;
ifabnor
- 20.0
base>
10005332 Investigations Blood antidiur Asymptomatic;Symptomatic;
c mHospitalization -
10005359 Investigations Blood bicarbon<LLN and no int- - -
10005364 Investigations Blood bilirubin >ULN - 1.5 x ULN>1.5if baseline
- 3.0 x ULNwas>3.0
if normal;
baseline
- 10.0 x>was
ULN
1.0
>10.0
normal;
-if1.5
baseline
xxULN
baseline
>1.5
ifwas
baseline
- 3.0
ifnormal;
baseline
x baseline
was>3.0
normal;
was
if- 10.0
base
abno>
10005452 Investigations Blood corticot Asymptomatic;Symptomatic;
c mHospitalization -
10005561 Investigations Blood gonadotAsymptomatic;Symptomatic;
c mSevere symptom -
10005630 Investigations Blood lactate >ULN - - -
10005778 Investigations Blood prolacti Asymptomatic;Moderate
c sympt - -
10065906 Investigations Carbon monoxid 3 - 5 units below
6 -LLN;
8 unitsfor below
follow-up,
Asymptomatic
LLN;afor decrease
follow-up,
decrease
- of 3an - 5asymptomatic
ofunits
>8 units
(ml/min/mm
drop;
decrease
>5 Hg)
unitsbelo
ofdr>
10007612 Investigations Cardiac troponiLevels above th- Levels consiste -
10007613 Investigations Cardiac troponLevels above th- Levels consiste -
10007839 Investigations CD4 lymphocyt<LLN - 500/mm3 <500 - 200/mm3 <200 - 50/mm3; <50/mm3; <0.0
10008661 Investigations Cholesterol hig>ULN - 300 mg/>300 - 400 mg/>400 - 500 mg/>500 mg/dL; >
10011268 Investigations CPK increased >ULN - 2.5 x U >2.5 x ULN - 5 >5 x ULN - 10 >10 x ULN
10011368 Investigations Creatinine inc >1 - 1.5 x baseline;
>1.5 >ULN
- 3.0 x- bas
1.5>3.0
x ULN x baseline;>6.0 >3.0x -ULN 6.0 x ULN
10050528 Investigations Ejection fracti - Resting ejectio Resting ejectionResting fraction ejectio
(EF) 39 - 20%; >=20% drop f
10014383 Investigations Electrocardiog Average QTc 450 Average
- 480 ms QTc 481Average- 500QTc ms >=QTc 501>=ms; 501>60or ms
>60change
ms change
fromfrom baselin
ba
10050380 Investigations Electrocardiog T wave flatteniNonspecific ST - -
10016596 Investigations Fibrinogen dec<1.0 - 0.75 x LLN;<0.75
or if- 0.5
abnormal,
x LLN;
<0.5 or
<25%
-if0.25
abnormal,
decrease
x LLN;
<0.25or
25from
ifx- abnormal,
LLN;
<50%
baseline
ordecrease
if abnormal,
50 - <75%
from75% decrease
baseline
decr
10016987 Investigations Forced expirat FEV1% (percentFEV1 60 - 69% 50 - 59% <= 49%
10056910 Investigations GGT increased >ULN - 2.5 x ULN >2.5
if baseline
- 5.0 x ULN was
>5.0
if normal;
baseline
- 20.0 x2.0 was
ULN
>20.0
- 2.5
normal;
if baseline
xxbaseline
ULN >2.5
ifwas
baseline
-if5.0
baseline
normal;
x baseline
was>5.0
was
normal;
ifabnor
- 20.0
base>
10018748 Investigations Growth hormoAsymptomatic;Symptomatic;
c m- -
10019150 Investigations Haptoglobin d <LLN - - -
10055599 Investigations Hemoglobin in If baseline is above
Increase
ULN,iniIncrease
>2 -Increase
4 gm/dLin >0inabove
- >4
2 gm/dL
gm/dL
- ULNabove or
above
aboveULN
ULNbaseline
or
orabove
aboveif baseline
baselineisif
10022402 Investigations INR increased >1.2 - 1.5 x ULN; >1.5
>1 -- 2.5
1.5 xtimes
ULN;>2.5
above
>1.5 x ULN;
- x2.5
baseline
>2.5
times
- times
above
if onaboveanticoagulation;
x baseline
x baseline
if on ifanticoagula
monitoring
on anticoa
10022891 Investigations Investigations Asymptomatic Moderate;
or minim
10024574 Investigations Lipase increas >ULN - 1.5 x U >1.5 - 2.0 x ULN; >2.0>2.0 - 5.0
- 5.0
x ULN
x ULN
>5.0
withand
x ULN
signs
asymptomatic
and
or symptoms;
with signs or >5.0
symptom
x ULN
10025256 Investigations Lymphocyte co<LLN - 800/mm3 <800 - 500/mm3 <500 - 200/mm3 <200/mm3; <0.
10025258 Investigations Lymphocyte co - >4000/mm3 - >20,000/mm3 -
10029366 Investigations Neutrophil cou<LLN - 1500/mm <1500 - 1000/m <1000 - 500/mm <500/mm3; <0.
10062646 Investigations Pancreatic enz<LLN and asymIncrease in sto Sequelae of ab -
10035528 Investigations Platelet count <LLN - 75,000/<75,000 - 50,0 <50,000 - 25,0 <25,000/mm3; <
10040139 Investigations Serum amylase>ULN - 1.5 x U >1.5 - 2.0 x ULN; >2.0>2.0 - 5.0
- 5.0
x ULN
x ULN
>5.0
withand
x ULN
signs
asymptomatic
and
or symptoms;
with signs or >5.0
symptom
x ULN
10043770 Investigations Thyroid stimul TSH increased a- - -
Infants: < 0.5 mL/kg per hour for 24 hours;
10059895 Investigations Urine output d - - Children: < 500Pediatric: mL/1.73 m2 No urine
body surface
output overarea 12perhod
10047580 Investigations Vital capacity 90 - 75% of pre<75 - 50% of pr<50% of predict-
10047896 Investigations Weight gain 5 - <10% from 10 - <20% from>=20% from ba -
10047900 Investigations Weight loss 5 to <10% from10 - <20% from>=20% from bas-
10049182 Investigations White blood ce<LLN - 3000/mm <3000 - 2000/m <2000 - 1000/m <1000/mm3; <1
10000486 Metabolism and Acidosis pH <normal, bu- pH <7.3 Life-threateni
10001598 Metabolism and Alcohol intole - Present Severe symptom Life-threateni
10001680 Metabolism and Alkalosis pH >normal, bu- pH >7.5 Life-threateni
10002646 Metabolism and Anorexia Loss of appetitOral intake alt Associated withLife-threateni
10012174 Metabolism and Dehydration Increased oral IV fluids indicated IV fluids
<24 hrs or hHospitalization
Life-threateniindicated
10052426 Metabolism and Glucose intole Asymptomatic;Symptomatic;
c di
10020587 Metabolism and HypercalcemiaCorrected seruCorrected seruCorrected serum Corrected seru
10020639 Metabolism and HyperglycemiaAbnormal glucose Change
above in daily
baseline
Insulin
management
with therapy
no medical
>500
from
initiated;
baseline
mg/dL;
intervention
>250>27.8
for
- 500
a mmol/L;
Fasting
diabetic;
mg/dL; glucose
lLife-thre
oral
>13.9 anti
va
-2
10020647 Metabolism and Hyperkalemia >ULN - 5.5 mm>5.5 - 6.0 mmol/L; >6.0intervention
- 7.0 mmol>7.0 initiated
mmol/L; l
10020667 Metabolism and HyperlipidemiaRequiring diet Requiring pharHospitalizationLife-threateni
10020670 Metabolism and Hypermagnese>ULN - 3.0 mg/ - >3.0 - 8.0 mg/d>8.0 mg/dL; >3
10020680 Metabolism and Hypernatremia>ULN - 150 mm>150 - 155 mmol/L; >155 intervention
- 160 mmol >160 initiated
mmol/L; l
10020712 Metabolism and HyperphosphaLaboratory findNoninvasive inSevere or medic Life-threatenin
10020870 Metabolism andHypertriglycer 150 mg/dL - 30>300 mg/dL - 5>500 mg/dL - 1>1000 mg/dL; >
10020907 Metabolism andHyperuricemia>ULN - 10 mg/dL - (0.59 mmol/L)>ULN
without
- 10 mg/dL
physiologic
>10(0.59
mg/dL;
consequences
mmol/L)
>0.59with
mmol/L;
physiologic
lLife-threa
con
10020943 Metabolism andHypoalbumine<LLN - 3 g/dL; <3 - 2 g/dL; <30<2 g/dL; <20 g/Life-threateni
10020949 Metabolism andHypocalcemia Corrected seruCorrected seruCorrected serum Corrected seru
10021005 Metabolism andHypoglycemia <LLN - 55 mg/d<55 - 40 mg/dL<40 - 30 mg/dL<30 mg/dL; <1.
10021018 Metabolism andHypokalemia <LLN - 3.0 mmoSymptomatic with <3.0<LLN
- 2.5 -mmol
3.0 mmol/L;
<2.5 mmol/L;symptomatic;
l intervention in
10021028 Metabolism andHypomagnesem <LLN - 1.2 mg/<1.2 - 0.9 mg/d<0.9 - 0.7 mg/d<0.7 mg/dL; <0
10021038 Metabolism andHyponatremia <LLN - 130 mm125-129 mmol/125-129 mmol/L <120symptomatic;
mmol/L; l 120-124 mmol/L rega
10021059 Metabolism andHypophosphatLaboratory finding Oralonly
replacement
and intervention
Severe
therapy
or medically
not
indicated
<1.0
indicated
mg/dL;
significant
<2.5<LLN
-<0.3
2.0but
-mg/dL;
mmol/L;
2.5not
mg/dL;
immediately
<0.8
Life-threate
<LLN
- 0.6 -mm
0.
10065973 Metabolism andIron overload - Moderate sympt Severe symptom Life-threateni
10027433 Metabolism andMetabolism and Asymptomatic Moderate;
or minim
Severe or medically
Life-threateni
10029883 Metabolism andObesity - BMI 25 - 29.9 BMI 30 - 39.9 BMI >=40 kg/m
10045152 Metabolism andTumor lysis sy - - Present Life-threateni
10065775 MusculoskeletaAbdominal soft - Local wound car Operative debridement
Life-threateni
or other invasive interventio
10003239 MusculoskeletaArthralgia Mild pain Moderate pain;Severe pain; li -
10003246 MusculoskeletaArthritis Mild pain with Moderate painSeverea pain associated
- with signs of inflammation, e
10066480 MusculoskeletaAvascular necrAsymptomatic;Symptomatic;
c lSevere symptoms Life-threateni
10003988 MusculoskeletaBack pain Mild pain Moderate pain;Severe pain; li -
10006002 MusculoskeletaBone pain Mild pain Moderate pain;Severe pain; li -
10048677 MusculoskeletaButtock pain Mild pain Moderate pain;Severe pain; li -
10048831 MusculoskeletaChest wall necr- Local wound car Operative debriLife-threateni
10008496 MusculoskeletaChest wall painMild pain Moderate pain;Severe pain; li -
10015688 MusculoskeletaExostosis Asymptomatic;Symptomatic;
c lSevere symptoms -
10065799 MusculoskeletaFibrosis deep cMild indurationModerate indura Severe induration;
Generalized;
unable toaslide or pinch skin; limi
10016750 MusculoskeletaFlank pain Mild pain Moderate pain;Severe pain; li -
10062572 MusculoskeletaGeneralized m Symptomatic; weakness
Symptomatic;
perceived
weakness
Weakness
by patient
evident
lLimiting
- but
onself
not
physical
care
evident
ADL;
exam;
ondisabling
physical
weakness exam
limiti
10018761 MusculoskeletaGrowth suppreReduction in grReduction in grReduction in gr -
10065779 MusculoskeletaHead soft tissu - Local wound car Operative debridement
Life-threateni
10023215 MusculoskeletaJoint effusion Asymptomatic;Symptomatic;
c lSevere symptoms; - limiting self care ADL; elective op
10048706 MusculoskeletaJoint range of <=25% loss of R>25 - 50% decr>50% decrease -in ROM; limiting self care ADL; disab
10065796 MusculoskeletaJoint range of Mild restrictio Rotation <60 deAnkylosed/fuse-
10065800 MusculoskeletaJoint range of Stiffness; diffi Pain with range<50% lumbar spi -
10023509 MusculoskeletaKyphosis Asymptomatic;Moderate
c accenSevere accentua-
10024842 MusculoskeletaLordosis Asymptomatic;Moderate
c accenSevere accentua-
10028294 MusculoskeletaMuscle cramp Mild pain Moderate pain;Severe pain; li -
10065776 MusculoskeletaMuscle weakneSymptomatic; pSymptomatic; eLimiting self care - ADL; disabling
10028395 MusculoskeletaMusculoskeletalAsymptomatic Moderate;
or minim
Severe or medically
Life-threateni
10065783 MusculoskeletaMusculoskeletaCosmetically anDeformity, hypo Significant deformity,
- hypoplasia, or asymmetry, una
10028411 MusculoskeletaMyalgia Mild pain Moderate pain;Severe pain; li -
10028653 MusculoskeletaMyositis Mild pain Moderate painPain associatedLife-threateni
10028836 MusculoskeletaNeck pain Mild pain Moderate pain;Severe pain; li -
10065781 MusculoskeletaNeck soft tissu - Local wound car Operative debridement
Life-threateni
10031264 MusculoskeletaOsteonecrosis Asymptomatic;Symptomatic;
c me
10064658 MusculoskeletaOsteonecrosis Asymptomatic;Symptomatic;
c me
10031282 MusculoskeletaOsteoporosis Pediatric: Radiologic
Pediatric:
evidence
Low Pediatric:
BMD
of low
(z-score
BMD
Limiting
with
<=- -2.0)
zself
score
and
careof
significant
ADL
<= -2.0 and
fracture
no history
history
o
10033425 MusculoskeletaPain in extremiMild pain Moderate pain;Severe pain; li -
10065793 MusculoskeletaPelvic soft tiss - Local wound car Operative debridement
Life-threateni
10039020 MusculoskeletaRhabdomyolysiAsymptomatic,Non-urgent
i intSymptomatic, uLife-threatenin
10039226 MusculoskeletaRotator cuff in Asymptomatic Moderate;
or minim
Severe or medic-
10039722 MusculoskeletaScoliosis <20 degrees; cl>20 - 45 degree>45 degrees; scapular
- prominence in forward flexion
10065777 MusculoskeletaSoft tissue nec - Local wound car Operative debridement
Life-threateni
10065778 MusculoskeletaSoft tissue nec - Local wound car Operative debridement
Life-threateni
10065798 MusculoskeletaSuperficial softMild indurationModerate indura Severe induratiGeneralized; a
10044684 MusculoskeletaTrismus Decreased ROM Decreased ROM Decreased ROM-
10065738 MusculoskeletaUnequal limb l Mild length di Moderate length Severe length discrepancy
- >5 cm; limiting self care A
10048293 Neoplasms beniLeukemia seco - - - Present
10028533 Neoplasms beniMyelodysplast - - - Life-threateni
10029104 Neoplasms beniNeoplasms benig Asymptomatic Moderate;
or minim
Severe or medically
Life-threateni
10040907 Neoplasms beniSkin papillomaAsymptomatic;Intervention in - -
10049737 Neoplasms beniTreatment rela - - Non life-threa Acute life-thre
10055351 Neoplasms beniTumor hemorrMild symptoms; Moderate sympt Transfusion indLife-threateni
10045158 Neoplasms beniTumor pain Mild pain Moderate pain;Severe pain; li -
10053662 Nervous systemAbducens nerve Asymptomatic;Moderate
c symptSevere symptom -
10060929 Nervous systemAccessory nervAsymptomatic;Moderate
10000521 Nervous systemAcoustic nerveAsymptomatic;Moderate
10001540 Nervous systemAkathisia Mild restlessneModerate restle Severe restless -
10001949 Nervous systemAmnesia Mild; transien Moderate; shorSevere; long te -
10002653 Nervous systemAnosmia Present - - -
10002953 Nervous systemAphonia - - Voicelessness; -
10003074 Nervous systemArachnoiditis Mild symptom Moderate sympt Severe symptom Life-threateni
10003591 Nervous systemAtaxia Asymptomatic;Moderate
c symptSevere symptoms -
10065417 Nervous systemBrachial plexo Asymptomatic;Moderate
10065784 Nervous systemCentral nervouAsymptomatic;Moderate
c symptSevere symptom Life-threateni
10008164 Nervous systemCerebrospinal fPost-craniotomPost-craniotomSevere symptom Life-threateni
10009845 Nervous systemCognitive dist Mild cognitive Moderate cognit Severe cognitiv -
10010250 Nervous systemConcentration Mild inattentioModerate impai Severe impairme -
10012373 Nervous systemDepressed leveDecreased levelSedation; slow Difficult to aro Life-threatening consequences; coma
10013573 Nervous systemDizziness Mild unsteadinModerate unste Severe unstead-
10013887 Nervous systemDysarthria Mild slurred s Moderate impai Severe impairme -
10062872 Nervous systemDysesthesia Mild sensory alModerate senso Severe sensory -
10013911 Nervous systemDysgeusia Altered taste bAltered taste w- -
10013951 Nervous systemDysphasia Awareness of reModerate recep Severe receptiv-
10014217 Nervous systemEdema cerebra - - New onset; worLife-threateni
10014625 Nervous systemEncephalopathMild symptom Moderate sympt Severe symptom Life-threateni
10015832 Nervous systemExtrapyramidalMild involunt Moderate involSevere involuntLife-threateni
10051272 Nervous systemFacial muscle Asymptomatic;Moderate
10061457 Nervous systemFacial nerve di Asymptomatic;Moderate
10061185 Nervous systemGlossopharynge Asymptomatic;Moderate
c symptSevere symptom Life-threateni
10018767 Nervous systemGuillain-Barre Mild symptom Moderate sympt Severe symptom Life-threatenin
10019211 Nervous systemHeadache Mild pain Moderate pain;Severe pain; li -
10020508 Nervous systemHydrocephalusAsymptomatic;Moderate
c sympt
10020765 Nervous systemHypersomnia Mild increasedModerate increSevere increas -
10061212 Nervous systemHypoglossal neAsymptomatic;Moderate
c sympt
Severe symptom -
10022763 Nervous systemIntracranial h Asymptomatic;Moderate
c symptoms;
Ventriculostomy,
medicalLife-threateni
intervention
ICP monitoring,indicated
intraventricular th
10023030 Nervous systemIschemia cerebAsymptomatic;Moderate
c sym - -
10065836 Nervous systemIVth nerve diso[Term deleted.[Term
Map to deleted.
Trochlear
[Term
Map nerve
to
deleted.
Trochlear
disorder,
-Mapnerve
Grade
to Trochlear
disorder,
1.] Asymptomatic;
nerve
Gradedisorder,
2.] Modera
clinical
Gra
10024264 Nervous systemLethargy Mild symptoms; Moderate sympt - -
10024382 Nervous systemLeukoencephalAsymptomatic;Moderate
s sympt
Severe symptom Life-threatenin
10027175 Nervous systemMemory impaiMild memory iModerate memor Severe memory-
10027198 Nervous systemMeningismus Mild symptom Moderate sympt Severe symptom Life-threateni
10028041 Nervous systemMovements invMild symptom Moderate sympt Severe symptom -
10028417 Nervous systemMyasthenia graAsymptomatic Moderate;
or minim
Severe or medic Life-threateni
10029205 Nervous systemNervous systemAsymptomatic Moderate;
or minim
Severe or medically
Life-threateni
10029223 Nervous systemNeuralgia Mild pain Moderate pain;Severe pain; li -
10029864 Nervous systemNystagmus - Moderate sympt Severe symptom -
10053661 Nervous systemOculomotor ner Asymptomatic;Moderate
c sympt
Severe symptom -
10056388 Nervous systemOlfactory nerve- Moderate sympt Severe symptom -
10033987 Nervous systemParesthesia Mild symptom Moderate sympt Severe symptom -
10034580 Nervous systemPeripheral motAsymptomatic;Moderate
clinical or sympt
diagnostic
Severe observations
symptoms;
Life-threateni
limiting
only; intervention
self care ADL; notassistive
indicated
de
10034620 Nervous systemPeripheral sen Asymptomatic;Moderate
loss of deepsympt
tendon
Severereflexes
symptom Lor
ife-threateni
paresthesia
10056238 Nervous systemPhantom pain Mild pain Moderate pain;Severe pain; li -
10036653 Nervous systemPresyncope - Present (e.g., n - -
10063636 Nervous systemPyramidal trac Asymptomatic;Moderate
c sympt
10061928 Nervous systemRadiculitis Mild symptom Moderate symptoms; Severe symptom
medicalLife-threateni
intervention indicated; limiting instr
10038130 Nervous systemRecurrent lary Asymptomatic;Moderate
c symSevere symptoms Life-threateni
10063761 Nervous systemReversible pos [Grade deleted.Moderate
Map to Nervous
symptoms;
Severe
systemsymptoms;
abnormal
disorders
Life-threatening
imaging
very
- Other,
abnormal
studies;
specify
consequences;
imaging
limiting
(Reversible
studies;
instrumen
urgen
posli
10039906 Nervous systemSeizure Brief partial seizure;
Brief generaliz
and no loss
New of onset
consciousness
seizures
Life-threatening
(partial or generalized);
consequences; mMultip
prolo
10041349 Nervous systemSomnolence Mild but more Moderate sedat Obtundation orLife-threateni
10041416 Nervous systemSpasticity Mild or slight Moderate increSevere increaseLife-threatening consequences; unab
10041549 Nervous systemSpinal cord co - - Severe symptom Life-threateni
10042244 Nervous systemStroke Asymptomatic Mildor mild
to moderate
neurologic
Severe
neurologic
deficit;
neurologic
Incidental
deficit;
Life-threateni
deficit;
limiting
radiographic
limiting
instrumental
self
findings
care ADL;
ADL
onlyhosp
10042772 Nervous systemSyncope - - Fainting; ortho -
10043245 Nervous systemTendon reflex Ankle reflex r Ankle reflex abAbsence of all -
10044391 Nervous systemTransient ischeMild neurologicModerate neuro- -
10044565 Nervous systemTremor Mild symptom Moderate sympt Severe symptom -
10060890 Nervous systemTrigeminal ner Asymptomatic;Moderate
c sympt
Severe symptom -
10074765 Nervous systemTrochlear nervAsymptomatic;Moderate
c sympt
Severe symptom -
10061403 Nervous systemVagus nerve diAsymptomatic;Moderate
c sympt
10047166 Nervous systemVasovagal reac - - Present Life-threateni
10065780 Nervous systemMuscle
disorders
weaknes
Musculoskeletal
Symptomatic;and pSymptomatic;
connective eLimiting
tissue disorders
self care
- ADL; disabling
10065794 Nervous systemMuscle
disorders
weaknes
Musculoskeletal
Symptomatic;and pSymptomatic;
connective eLimiting
tissue disorders
self care
- ADL; disabling
10016479 Pregnancy, pueFetal death - - - -
10054746 Pregnancy, pueFetal growth r - <10% percentile <5% percentile<1% percentile
10072314 Pregnancy, puePregnancy loss - - - Fetal loss at a
10036585 Pregnancy, puePregnancy, puer Asymptomatic Moderate;,
or minimal,
Severelocal
or medically
or noninvasive
Life-threateni
significant
intervention
but not immediately
indicated; lim
10036595 Pregnancy, puePremature deliDelivery of a l Delivery of a l Delivery of a l Delivery of a l
10045542 Pregnancy, pueUnintended pr - - [Term deleted. -Map to Pregnancy, puerperium and p
10001497 Psychiatric dis Agitation Mild mood alteModerate mood Severe agitatioLife-threateni
10002652 Psychiatric dis Anorgasmia Inability to ac Inability to ac - -
10002855 Psychiatric dis Anxiety Mild symptoms; Moderate sympt Severe symptoms; Life-threatening
limiting self careconsequences;
ADL; hospitaliza hospi
10010300 Psychiatric dis Confusion Mild disorientaModerate disorSevere disorienLife-threateni
10057066 Psychiatric dis Delayed orgas Delay in achievDelay in achiev - -
10012218 Psychiatric dis Delirium Mild acute confModerate and Severea and acuteLife-threatening
confusional state; consequences,
limiting selfthreacare
10012260 Psychiatric dis Delusions - Moderate deluSevere delusional Life-threatenin
symptoms; hospitalization not ind
10012378 Psychiatric dis Depression Mild depressi Moderate depre Severe depressiLife-threatenin
10015533 Psychiatric dis Euphoria Mild mood elevModerate mood Severe mood el-
10019077 Psychiatric dis Hallucinations Mild hallucinatModerate halluSevere hallucinLife-threatenin
10022437 Psychiatric dis Insomnia Mild difficulty Moderate difficSevere difficult -
10024419 Psychiatric dis Libido decreas Decrease in sexDecrease in sex- -
10024421 Psychiatric dis Libido increasePresent Mild increase
[Grade deleted.
in sexual
[Grade
Map
interest
to
deleted.
Libido
not adversely
-increased,
Map to Libido
affecting
Gradeincreased,
1.]
relationship
ModerateGradeincre
1.] S
10026749 Psychiatric dis Mania Mild manic symModerate manic Severe manic symptoms
Life-threatenin
(e.g., hypomania; major sex
10034719 Psychiatric dis Personality ch Mild personali Moderate perso Severe personal Life-threatenin
10037175 Psychiatric dis Psychiatric dis Asymptomatic Moderate;
or minim
Severe or medically
Life-threatenin
10037234 Psychiatric dis Psychosis Mild psychoti Moderate psycho Severe psychotic Life-threatenin
symptoms (e.g., paranoid;, extrem
10038743 Psychiatric dis Restlessness Mild symptoms; Moderate sympt Severe symptom -
10042458 Psychiatric dis Suicidal ideati Increased thoug Suicidal ideati Specific plan t Specific plan t
10042464 Psychiatric dis Suicide attemp - - Suicide attemptSuicide
or gesture
attemptwithout intent to die whi
10022998 Psychiatric disorders
Irritability
General Mild;
disorders
easily
and
co administration
Moderate; limitSevere
site conditions
abnormal - or excessive response; limiting self
10069339 Renal and urinaAcute kidney in[Grade deleted.[GradeMap todeleted.
Creatinine
Creatinine
Mapincreased,
to Creatinine
>3 xLife-threatenin
baseline
Gradeincreased,
2.]orCreatinine
>4.0Grade
mg/dL; level
2.]hHospitaliza
Creatinine
increase o
10063575 Renal and urinaBladder perfor - ExtraperitonealIntraperitoneal
perforation, indwelling
Life-threatenin
perforation;catheter
elective
indicated
radiologic,Invasive
endo
10048994 Renal and urinaBladder spasmIntervention noAntispasmodicsHospitalization -
10064848 Renal and urinaChronic kidneyeGFR (estimated eGFR or CrCl 5 eGFR or CrCl 2 eGFR or CrCl <1
10063057 Renal and urinaCystitis noninf Microscopic hem Moderate hematu Gross hematuria; Life-threatening
transfusion, IVconsequences;
medications, or urgen
hos
10013990 Renal and urinaDysuria Present - - -
10068405 Renal and urinaGlucosuria Present - - -
10019450 Renal and urinaHematuria Asymptomatic;Symptomatic;
c ur
Gross hematuria; Life-threatening
transfusion, IVconsequences;
medications, or urgen
hos
10019489 Renal and urinaHemoglobinuriAsymptomatic; -c - -
10029164 Renal and urinaNephrotic syn - - Not immediately Life-threateni
10037032 Renal and urinaProteinuria 1+ proteinuria;Pediatric:
urinary protein
urinePediatric:
P/C
≥ULN(Protein/Creatinine)
- <1.0
Uurine
g/24
- P/Chrs(Protein/Creatinine)
ratio 0.5 - 1.9 ratio >1.9
10038359 Renal and urinaRenal and urinaAsymptomatic Moderate;,
or minimal,
Severelocal
or medically
or noninvasive
Life-threateni
significant
intervention
but not immediately
indicated; lim
10038385 Renal and urinaRenal calculi Asymptomatic Symptomatic;
o or
HospitalizationLife-threatening
indicated; IV intervention
consequences; (e.g., urgen
analg
10038419 Renal and urinaRenal colic Mild pain not i Moderate pain;Hospitalization -
10038463 Renal and urinaRenal hemorrhMild symptoms; Analgesics andTransfusion, radiation,
Life-threatening
or hospitalization
consequences; indicated;
urgene
10065368 Renal and urinaUrinary fistula - Symptomatic, Noninvasive
Limiting self intervention
care
Life-threatening
ADL; elective
not indicated;
radiologic,
consequences;
urinary
endoscopi
urgen
or su
10046539 Renal and urinaUrinary frequePresent Limiting instr - -
10046543 Renal and urinaUrinary incont Occasional (e.gSpontaneous; pIntervention in -
10046555 Renal and urinaUrinary retent Urinary, suprapPlacement of uElective operative Life-threatenin
or radiologic invasive intervention
10061574 Renal and urinaUrinary tract o Asymptomatic;Symptomatic
but
Symptomatic
no hydronephrosis,
observations
and
Life-threateni
aAltered
only;
sepsis,
intervention
organ
or renal
functiondysfunction;
not (e.g.,
indicated
hydu
10062225 Renal and urinaUrinary tract pMild pain Moderate pain;Severe pain; li -
10046593 Renal and urinaUrinary urgencPresent Limiting instr - -
10046628 Renal and urinaUrine discoloraPresent - - -
10001927 Reproductive sAmenorrhea - Present - -
10003883 Reproductive sAzoospermia - Absence of spe[Grade deleted.- Map to Azoospermia, Grade 2.] Abs
10006179 Reproductive sBreast atrophyMinimal asymmModerate asymAsymmetry >1/3 -
10006298 Reproductive sBreast pain Mild pain Moderate pain;Severe pain; li -
10013934 Reproductive sDysmenorrheaMild symptoms; Moderate sympt Severe symptom -
10013941 Reproductive sDyspareunia Mild discomfortModerate discom Severe discomfo-
10014326 Reproductive sEjaculation dis Diminished ejaAnejaculation o- -
10061461 Reproductive sErectile dysfunDecrease in ereDecrease in ereDecrease in ere-
10065789 Reproductive sFallopian tube Asymptomatic;SymptomaticMild
clinical or Ddiagnostic
Severe
symptoms;
symptoms;
observations
elective
- elective only;
intervention
operative
intervention
indicated
invasive
not indicate
interv
10065791 Reproductive sFallopian tube [Term deleted.[Term
Map to deleted.
Reproductive
[Term
Map to deleted.
system
Reproductive
[Term
and
Mapbreast
to
deleted.
system
Reproductive
disorders
and
Mapbreast
to-system
Other,
Reproductive
disorders
specify
and bre-
10061149 Reproductive sFemale genital[Term deleted.[Term
Map to deleted.
Reproductive
[Term
Map to deleted.
system
Reproductive
[Term
and
Mapbreast
to
deleted.
system
Reproductive
disorders
and
Mapbreast
to-system
Other,
Reproductive
disorders
specify
and bre-
10054382 Reproductive sFeminization aMild symptoms; Moderate sympt - -
10018146 Reproductive sGenital edemaMild swelling oReadily apparen Lymphorrhea; g-
10018801 Reproductive sGynecomastia Asymptomatic Symptomatic
breast enlargement
(e.
Severe symptom -
10060602 Reproductive sHematosalpinxMinimal bleedin Moderate bleed Severe bleeding; Life-threateni
10022992 Reproductive sIrregular mens Intermittent/irregular
Intermittent/irregular
menses[Grade
with skipped
deleted.
mensesmenses
-with
Mapskipped
tofor
Amenorrhea,
no menses
more than for
Grade
3more
consecutiv
2.]than
Pers
10061261 Reproductive sLactation disorMild changes inChanges in lact - -
10027313 Reproductive sMenorrhagia Mild; iron sup Moderate sympt Severe; transfusion
Life-threateni
indicated; surgical operative inte
10065823 Reproductive sNipple deformiAsymptomatic;Symptomatic; a- -
10030300 Reproductive sOligospermia Sperm concentration
[Grade>48deleted.
0 to[Grade
<Map
15 million/mL
to
deleted.
Oligospermia,
- Map
or motility
to Grade
Oligospermia,
>68%
1.] Sperm Grade
concentrati
1.] Spe
10065763 Reproductive sOvarian hemorMild symptoms; Moderate
bleeding
Severe identified
bleeding;
Life-threatening
onmedical
tTransfusion
imaging intervention
study
indicated;
consequences;
or laproscopy;
indicated
radiologic
urgen
inteo
10033279 Reproductive sOvarian rupturAsymptomatic Symptomatic
cl anTransfusion, radiologic,
Life-threateni endoscopic, or elective oper
10033314 Reproductive sOvulation pain [Grade deleted.Present
Map toModerate
Ovulation
[Gradepain;
pain,
deleted.
limiting
Grade- Map
2.]
instrumental
Mild
to Ovulation
pain ADLpain, Grade 2.] Se
10064026 Reproductive sPelvic floor m Asymptomatic;Symptomatic,
c no
Severe symptom [Grade deleted. Map to Reproductive
10034263 Reproductive sPelvic pain Mild pain Moderate pain;Severe pain; li -
10034310 Reproductive sPenile pain Mild pain Moderate pain;Severe pain; li -
10061339 Reproductive sPerineal pain Mild pain Moderate pain;Severe pain; li -
10036601 Reproductive sPremature me - Present [Grade deleted.- Map to Premature menopause, Gra
10055325 Reproductive sProstatic hemoMild symptoms; Moderate
bleeding
Severe identified
bleeding;
Life-threatening
onmedical
tTransfusion
study;
indicated;
consequences;
intervention
indicated
radiologic
not
urgen
ino
10055026 Reproductive sProstatic obstr Asymptomatic;SymptomaticMild
Severe
symptoms;
symptoms;
observations
elective
- elective only;
intervention
operative
intervention
indicated
invasive
not indicate
interv
10036968 Reproductive sProstatic pain Mild pain Moderate pain;Severe pain; li -
10038604 Reproductive sReproductive sy Asymptomatic Moderate;
or minimSevere or medically
Life-threateni
10039757 Reproductive sScrotal pain Mild pain Moderate pain;Severe pain; li -
10065762 Reproductive sSpermatic cor Mild symptoms; Moderate
bleeding
Severe identified
bleeding;
Life-threatening
onmedical
tTransfusion
study;
indicated;
consequences;
intervention
indicated
radiologic
not
urgen
ino
10065805 Reproductive sSpermatic cordAsymptomatic;SymptomaticMild
Severe
symptoms;
symptoms;
observations
elective
- elective only;
intervention
operative
intervention
indicated
invasive
not indicate
interv
10043306 Reproductive sTesticular diso Asymptomatic;Symptomatic
c but
Severe
not interfering
symptoms;
Life-threateni
with
interfering
urinationwith
or urination
sexual function
or sexua
10055347 Reproductive sTesticular hemMild symptoms; Moderate
bleeding
Severe identified
bleeding;
Life-threatening
onmedical
tTransfusion
study;
indicated;
consequences;
intervention
indicated
radiologic
not
urgen
ino
10043345 Reproductive sTesticular painMild pain Moderate pain;Severe pain; li -
10065811 Reproductive sUterine fistula Asymptomatic;Symptomatic,
invasive
Severe observations
symptoms;
and intervention
Life-threateni
elective
only; notintervention
operative
indicated Invasive
not indicated
interv
10046789 Reproductive sUterine hemorMild symptoms; Moderate
bleeding
Severe identified
bleeding;
Life-threatening
onmedical
tTransfusion
study;
indicated;
consequences;
intervention
indicated
radiologic
not
urgen
ino
10065928 Reproductive sUterine obstru Asymptomatic;SymptomaticMild
Severe
symptoms;
symptoms;
observations
elective
- elective only;
intervention
operative
intervention
indicated
invasive
not indicate
interv
10046809 Reproductive sUterine pain Mild pain Moderate pain;Severe pain; li -
10046901 Reproductive sVaginal discha Mild vaginal diModerate to he- -
10046904 Reproductive sVaginal drynesMild vaginal drModerate vagina Severe vaginal -
10065813 Reproductive sVaginal fistula Asymptomatic;Symptomatic,
invasive
Severe observations
symptoms;
and intervention
Life-threateni
elective
only; not
intervention
operative
indicated Invasive
not indicated
interv
10046912 Reproductive sVaginal hemor Mild symptoms; Moderate
bleeding
Severeidentified
bleeding; Life-threatening
onmedical
tTransfusion
clinicalintervention
examindicated;
consequences;
or imaging
indicated
radiologic
study;urgen
int
o
10046916 Reproductive sVaginal inflam Mild discomforModerate discoSevere discomfo Life-threatening consequences; Wwid
10065817 Reproductive sVaginal obstru Asymptomatic;SymptomaticMild
Severe
symptoms;
symptoms;
observations
elective
- elective
only;
intervention
operative
interventionindicated
invasive
not indicate
interv
10046937 Reproductive sVaginal pain Mild pain Moderate pain;Severe pain; li -
10065818 Reproductive sVaginal perfora[Grade deleted.Symptomatic
Map to Reproductive
and
Severe
Invasive
symptoms;
system
intervention
Life-threateni
andelective
breastnotoperative
disorders
indicated-Invasive
Other, specify
interv
10053496 Reproductive sVaginal strictu Asymptomatic;Vaginal narrowVaginal narrowi-
10046947 Reproductive sVaginismus [Term deleted.[Term Map todeleted.
Reproductive
[Term
Map to deleted.
system
Reproductive
and
-Mapbreast
tosystem
Reproductive
disorders
and breast
-system
Other,
disorders
specify
and bre -
10001409 Respiratory, thAdult respirat - - Present with raLife-threateni
10001723 Respiratory, thAllergic rhinitisMild symptoms; Moderate sympt - -
10002972 Respiratory, thApnea - - Present; medica Life-threateni
10003504 Respiratory, thAspiration Asymptomatic;Altered
c eating Dyspnea and pn Life-threateni
10003598 Respiratory, thAtelectasis Asymptomatic;Symptomatic
c (e.
Supplemental oOxygen
Life-threateni
indicated; hospitalization or
10006437 Respiratory, thBronchial fistulAsymptomatic;Symptomatic,;
Severe
tube thoracostomy
observations
symptoms; Life-threatening
limiting
or
only;
medical
intervention
self care
management
consequences;
ADL;notendoscopic
indicated
invasiv
urgen
10006440 Respiratory, thBronchial obst Asymptomatic;Symptomatic
c (e.
Shortness of brLife-threateni
10063524 Respiratory, thBronchial stric Asymptomatic;Symptomatic
c (e.
Shortness of brLife-threateni
10053481 Respiratory, thBronchopleuralAsymptomatic;Symptomatic,;
Hospitalization;
tube thoracostomy
observations
Life-threatening
Severe
or
only;
medical
symptoms;
intervention
invasive
consequences;
limiting
not
intervention
indicated
self urgen
care
10065746 Respiratory, thBronchopulmoMild symptoms; Moderate symptoms;Transfusion
Symptomatic;
indicated,
Life-threatening
altered
radiologic,
GIconsequencesrespira
function,
endoscopic,invasive
or elein
10006482 Respiratory, thBronchospasmMild symptoms; Symptomatic; m Limiting self care Life-threateni
ADL; supplemental oxygen indicate
10051228 Respiratory, thChylothorax Asymptomatic;Symptomatic;
c medical
Severe symptom
intervention
Life-threateni
indicated (e.g., fat-restricted di
10011224 Respiratory, thCough Mild symptoms; Moderate sympt Severe symptom -
10013963 Respiratory, thDyspnea Shortness of b Shortness of brShortness of brLife-threateni
10015090 Respiratory, thEpistaxis Mild symptoms; Moderate sympto Transfusion, radiologic,
Life-threateni
endoscopic, or operative; inv
10020039 Respiratory, thHiccups Mild symptoms; Moderate sympt Severe symptoms -
10020201 Respiratory, thHoarseness Mild or intermiModerate or peSevere voice c -
10021143 Respiratory, thHypoxia - Decreased oxygDecreased oxygLife-threatenin
10023838 Respiratory, thLaryngeal ede Asymptomatic;Symptomatic;
c mStridor; respiraLife-threatenin
10065786 Respiratory, thLaryngeal fistu Asymptomatic;Symptomatic,;
Severe
tube thoracostomy
observations
symptoms; Life-threatening
limiting
or
only;
medical
intervention
self care
management
consequences;
ADL;notendoscopic
indicated
invasiv
urgen
10065759 Respiratory, thLaryngeal hemMild cough or tModerate symptoms; Transfusion
medicalindicated,
Life-threatening
intervention
radiologic,
indicated
consequencesairway
endoscopic, or ele
10065735 Respiratory, thLaryngeal infl Mild sore throaModerate soreSevere throat p-
10065880 Respiratory, thLaryngeal mucoEndoscopic findModerate discomfort Severe pain,
pain; analgesics
seLife-threatenin
indicated; altered oral intake
10059639 Respiratory, thLaryngeal obstAsymptomatic;Symptomatic
c (e.g.,
Limiting
noisy self
airway
caLife-threateni
breathing), but causing no respirat
10023862 Respiratory, thLaryngeal stenoAsymptomatic;Symptomatic
c (e.g.,
Limiting
noisy self
airway
caLife-threateni
10062667 Respiratory, thLaryngopharyng Mild symptoms; Moderate symptoms;Severe symptoms
mild anxiety,
Life-threateni
but no dyspnea; short duration
10023891 Respiratory, thLaryngospasm - Transient episoRecurrent episoPersistent or s
10056356 Respiratory, thMediastinal h Mildminimal symptoms;
Moderateintervention
symptoms;
Transfusion
medical
not indicated;
indicated,
Life-threateni
intervention
radiologic,
rRadiologic
indicated
endoscopic,
evidence only; or ele
10028735 Respiratory, thNasal congesti Mild symptoms; Moderate sympt Associated with-
10068319 Respiratory, thOropharyngealMild pain Moderate pain;Severe pain; se -
10034825 Respiratory, thPharyngeal fistAsymptomatic;Symptomatic,;
Severe
tube thoracostomy
observations
symptoms; Life-threateni
limiting
or
only;
medical
intervention
self care
invasive
ADL;not
intervention
endoscopic
indicated
10055315 Respiratory, thPharyngeal he Mild symptoms; Moderate symptoms;Transfusion
medicalindicated,
Life-threatening
intervention
radiologic,
indicated
consequencesrespira
endoscopic, or ele
10065881 Respiratory, thPharyngeal muc Endoscopic findModerate painSevereand, analgesics
pain; unLife-threateni
indicated; altered oral intake; limitin
10065706 Respiratory, thPharyngeal nec- - Inability to aliment
Life-threateni
10050028 Respiratory, thPharyngeal steAsymptomatic;Symptomatic
c (e.g.,
Limiting
noisy self
airway
caLife-threatenin
10034844 Respiratory, thPharyngolaryngMild pain Moderate pain;Severe pain; li -
10035598 Respiratory, thPleural effusio Asymptomatic;Symptomatic;
c intervention
Symptomaticindicated
with
Life-threateni
respiratory
(e.g., diuretics
distressorand
limited
hypoxia;
thera
10055319 Respiratory, thPleural hemor Asymptomatic;Symptomatic or>1000 ml of blood Life-threatening
evacuated; persistent
consequencesrespira
bleeding (1
10035623 Respiratory, thPleuritic pain Mild pain Moderate pain;Severe pain; li -
10035742 Respiratory, thPneumonitis Asymptomatic;Symptomatic;
c mSevere symptom Life-threatenin
10035759 Respiratory, thPneumothoraxAsymptomatic;Symptomatic;
c intervention
Sclerosis and/oLife-threateni
indicated (e.g., tube placement without
10036402 Respiratory, thPostnasal drip Mild symptoms; Moderate sympt - -
10036790 Respiratory, thProductive couOccasional/minModerate sputu Persistent or c -
10037375 Respiratory, thPulmonary ed Radiologic findModerate dyspn Severe dyspneaLife-threatenin
10037383 Respiratory, thPulmonary fibrMild hypoxemia; Moderate
rRadiologic
hypoxemia;
pulmonary
Severe hypoxemia;
eEvidence
fibrosis
Life-threateni
<25%
of
evidence
pulmonary
of lung
of right-sided
volume
hypertension;
associated
heartradio
failw
10065873 Respiratory, thPulmonary fist Asymptomatic;Symptomatic,;
Limiting
tube thoracostomy
observations
self care
Life-threatening
ADL;or
only;
endoscopic
medical
intervention
management
consequences;
stenting
not indicated
orinvasiv
operati
urgen
10037400 Respiratory, thPulmonary hypMinimal dyspneModerate dyspn Severe symptoms, Life-threatenin
associated with hypoxemia, right
10038695 Respiratory, thRespiratory fai - - - Life-threatenin
10038738 Respiratory, thRespiratory, thAsymptomatic Moderate;
or minimSevere or medically
Life-threateni
10038921 Respiratory, thRetinoic acid Fluid retentionModerate signsSevere symptom Life-threatenin
10039100 Respiratory, thRhinorrhea Present - - -
10062244 Respiratory, thSinus disorder Asymptomatic Symptomatic
m stStenosis with sNecrosis of sof
10040975 Respiratory, thSleep apnea Snoring and noModerate apnea Oxygen desaturation;
Cardiovascular
associated with pulmonary hy
10041232 Respiratory, thSneezing Mild symptoms; Moderate sympt - -
10041367 Respiratory, thSore throat Mild pain Moderate pain;Severe pain; lim-
10042241 Respiratory, thStridor - - Respiratory disLife-threatenin
10065787 Respiratory, thTracheal fistul Asymptomatic;Symptomatic,;
Severe
tube thoracostomy
observations
symptoms;Life-threatening
limiting
or
only;
medical
intervention
self care
invasive
consequences;
ADL;
not
intervention
endoscopic
indicated
urgen
10065900 Respiratory, thTracheal mucosEndoscopic fin Moderate sympt Severe pain; h Life-threateni
10050816 Respiratory, thTracheal stenosAsymptomatic;Symptomatic
c (e.g.,
Stridor
noisy
or respiratory
airwayLife-threatenin
breathing),
distressbut
limiting
causing
selfno
care
respirat
ADL;
10047681 Respiratory, thVoice alteratioMild or interm Moderate or peSevere voice ch-
10047924 Respiratory, thWheezing Detectable air Moderate sympt Severe respiratLife-threateni
10040747 Respiratory, thoracic
Sinus pain
and mediastinal
Mild paindisorders
Moderate
Nervous pain;
system
Severedisorders
pain; li -
10001760 Skin and subcuAlopecia Hair loss of <5 Hair loss of >= - -
10005901 Skin and subcuBody odor Mild odor; physPronounced odo - -
10006556 Skin and subcuBullous dermatiAsymptomatic;Blisters coveri Blisters coveri Blisters coveri
10013786 Skin and subcuDry skin Covering <10%Covering 10 - Covering >30% -B
10014184 Skin and subcuEczema Asymptomatic Moderate;
or mild symptoms; additional
topicSevere or medic-medical intervention over baseline n
10015218 Skin and subcuErythema multTarget lesions Target lesions Target lesions Target lesions
10015277 Skin and subcuErythroderma - Erythema coverErythema coveri Erythema coveri
10016241 Skin and subcuFat atrophy Covering <10%Covering 10 - Covering >30% -
10055525 Skin and subcuHair color cha Present - - -
10019049 Skin and subcuHair texture a Present - - -
10020112 Skin and subcuHirsutism In women, incre In women, incre- -
10020642 Skin and subcuHyperhidrosis Limited to one Involving
s >1 si Generalized involving
- sites other than palms, soles, o
10020649 Skin and subcuHyperkeratosisPresent - Limiting self-c -
10020864 Skin and subcuHypertrichosis Increase in len Increase in len - -
10021013 Skin and subcuHypohidrosis - Symptomatic; lIncrease in bodHeat stroke
10062315 Skin and subcuLipohypertrop Asymptomatic Covering 10 - Covering >30% -
10028689 Skin and subcuNail changes Present - - -
10028691 Skin and subcuNail discolorat Asymptomatic; -clinical or diagnostic- observations
- only; intervention not indicated
10049281 Skin and subcuNail loss Asymptomatic Symptomatic
se sep
- -
10062283 Skin and subcuNail ridging Asymptomatic; -c - -
10033474 Skin and subcuPain of skin Mild pain Moderate pain;Severe pain; li -
10054524 Skin and subcuPalmar-plantarMinimal skin chSkin changes (e.g., Severepeeling,
skin changes
blisters,
- (e.g.,
bleeding,
peeling,
fissures,
blisters,
edema,
bleeding,
or hy
10034966 Skin and subcuPhotosensitivitPainless eryth Tender erythem Erythema coveri Life-threateni
10037087 Skin and subcuPruritus Mild or localiz Intense or wWidespread;
Intense or wWidespread;
and -intermittent; andskin
constant;
changes limiting
from scrat
self
10037549 Skin and subcuPurpura Combined areaCombined areaCombined area-
10037847 Skin and subcuRash acneifor Papules and/orPapules and/orPapules pustulesand/or
covering
Life-threatening
pustules
10 - 30%covering
BSA, consequences;
which
>30% may
BSA, or
which
Ppap
maym
10037868 Skin and subcuRash maculo-pMacules/papule Macules/papules Macules/papules
covering 10 - 30% covering
BSA with
>30% orBSA
without
withsymptoms
or withou
10049120 Skin and subcuScalp pain Mild pain Moderate pain;Severe pain; li -
10040785 Skin and subcuSkin and subcutAsymptomatic Moderate;
or minim
Severe or medicallyLife-threateni
10040799 Skin and subcuSkin atrophy Covering <10%CoveringB 10 - 3Covering >30% -
10040865 Skin and subcuSkin hyperpigmHyperpigmentat Hyperpigmentat- -
10040868 Skin and subcuSkin hypopigmHypopigmentati Hypopigmentati- -
10051837 Skin and subcuSkin indurationMild indurationModerate indura Severe induration, Generalized;
unable toaslide or pinch skin; limiti
10040947 Skin and subcuSkin ulcerationCombined areaCombined areaCombined o areaAnyo size ulcer
10042033 Skin and subcuStevens-Johns - - Skin sloughing Skin covering
sloughing
<10% BSA with associated si
10042344 Skin and subcuSubcutaneous Asymptomatic Moderate;
or minim
Severe or medic-
10043189 Skin and subcuTelangiectasia Telangiectasia Telangiectasias -covering >=10% - BSA; associated with psychosocial
10044223 Skin and subcuToxic epidermal- - - Skin sloughing
10046735 Skin and subcuUrticaria Urticarial lesi Urticarial lesi Urticarial lesi -
10027308 Social circums Menopause [Term deleted.[Term Map todeleted.
Premature
[Term
Mapmenopause,
to
deleted.
Premature-Map
Grade
menopause,
to Premature
2.] Menopause
Grade
menopause,
2.]
occurring
Menopau
Gradat
10041244 Social circums Social circumstAsymptomatic Moderate;
or minim
10042613 Surgical and mSurgical and meAsymptomatic Moderate;
or minim
10073529 Vascular disordArterial thro - - Urgent interveLife-threateni
10007196 Vascular disordCapillary leak Asymptomatic Symptomatic; m Severe symptom Life-threateni
10016825 Vascular disordFlushing Asymptomatic;Moderate
clinical or symptoms;
diagnostic
Symptomatic,
observations
medicala-intervention
only; intervention
indicated; notlimiting
indicated
instr
10019428 Vascular disordHematoma Mild symptoms; Minimally invasTransfusion, radiologic,
Life-threateni
endoscopic, or elective oper
10020407 Vascular disordHot flashes Mild symptoms; Moderate sympt Severe symptom -
10020772 Vascular disordHypertension Adolescent: BPAdolescent:
≥ 120/80 even Systolic
Pediatric
if < 95th
between
and
percentile
adolescent:
Adult
130-139
andorPediatric:
diastolic Life-threatening
between 80-89 e
10021097 Vascular disordHypotension Asymptomatic,Non-urgent med Medical intervention
Life-threatening
indicated;or consequences
hospitalization
andindu
10065773 Vascular disordLymph leakage - Symptomatic; m Severe symptoms; Life-threateni
10025233 Vascular disordLymphedema Trace thickeninMarked discolor Severe symptom -
10048642 Vascular disordLymphocele Asymptomatic;Symptomatic;
c m
Severe symptoms; - radiologic, endoscopic or elective
10034578 Vascular disordPeripheral isc - Brief (<24 hrs) episode
Recurring ofor
ischemia
pProlonged
Life-threateni
managed
(>=24medically
hrs) or recurring
non-surgica
sym
10034879 Vascular disordPhlebitis - Present - -
10042554 Vascular disordSuperficial thr - Present - -
10042569 Vascular disordSuperior vena Asymptomatic;Symptomatic; me Severe symptoms Life-threatenin
10043565 Vascular disordThromboemboli Medical intervention
Venousnot thrombosis
indicated
Thrombosis
(e.g.,
Venousuncomplicated
(e.g.,
thrombosis
Life-threatening
uncomplicated
(e.g.,
deep superficial
consequences
vein
pulmonary
thrombosis),
thrombos
embolis
(e.g.,
mp
10047065 Vascular disordVascular disordAsymptomatic Moderate;
or minim
10047115 Vascular disordVasculitis Asymptomatic,Moderate sympt Severe symptoms Life-threatening consequences; evide
Grade 5 Definition Navigational Note CTCAE v5.0 Change
Death A disorder characterized by an reduction
Clarification:
in theDefinition
amount of hemoglobin in 100 ml of blood. Signs and symptoms
Death - Clarification: Grade 3
Death A disorder characterized by the inability of the bone marrow to produce hematopoietic elements.
Death A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot
- A disorder characterized by laboraAddition: Term
Death A disorder characterized by an ANC <1000/mm3 and a single temperature of >38.3 degrees C (101 degrees F) o
Death A disorder characterized by labor Clarification: Grade 2
Death A disorder characterized by a fo Deletion: Grade 1
Death A disorder characterized by laboratory test results that indicate an increased number of white blood cells in the
- A disorder characterized by a sensation of marked discomfort in a lymph node.
Death A disorder characterized by labor Addition: Term
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Map todeleted.
Blood and
Maplymphatic
to Blood system
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disorders
Term
system
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Death of the s
Death A disorder characterized by the pDeletion: Grade 1
[Term deleted.[Term
Map todeleted.
Myocardial
Map infarction,
to Chest pain-cardiac.]
Grade
Deletion:
5.] Death
Term
A disorder characterized by signs and symptoms related to acute isc
Death A disorder characterized by a defect in aortic valve function or structure.
Death A disorder characterized by a dysrhythmia without cardiac electrical activity. Typically, this is accompanied by c
Death A disorder characterized by a dys Clarification: Grade 3, 4
Death A disorder characterized by a dysrClarification: Grade 3
- A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical i
Death A disorder characterized by cessation of the pumping function of the heart.
- A disorder characterized
Also considerby substernal
CardiAddition:
discomfort
Navigational
due tonote;
insufficient
Clarification:
myocardial
Gradeoxygenation
2, 3, Definition
e.g., angina pecto
Death A disorder characterized by patholClarification: Grade 2, 3, 4
[Term deleted.[Term
Map todeleted.
Pericarditis,
Map to Grade
Pericarditis]
5.] Death
Deletion:
A disorder
Termcharacterized by a thickened and fibrotic pericardial sac; these fi
- A disorder characterized by a blu Addition: Term
Death A disorder charIf left sided use C Addition: Navigational note; Clarification: Grade 2, 3
Death A disorder characterized
Also considerby failure
InvesAddition:
of the left
Navigational
ventricle tonote;
produce
Clarification:
adequateDefinition
output. despite an increase in diste
Death A disorder characterized by a defect in mitral valve function or structure.
Death A disorder characterized by a dysrh Clarification: Grade 3
Death A disorder characterized by a dysrhythmia with a progressively lengthening PR interval prior to the blocking of a
Death A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to t
Death A disorder characterized by infla Clarification: Grade 2, 3; Deletion: Grade 1
- A disorder characterized by an unpleasant sensation of irregular and/or forceful beating of the heart.
Death A disorder characterized by fluid collection within the pericardial sac, usually due to inflammation.
Death A disorder characterized by an increase in intrapericardial pressure due to the collection of blood or fluid in the
Death A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart).
Death A disorder characterized by a defect in pulmonary valve function or structure.
Death A disorder characterized by an inab Addition: Grade 1, 2; Clarification: Grade 3
Death A disorder characterized by impairClarification: Grade 2, 3
Death A disorder characterized by a dysrClarification: Grade 2, 3
- A disorder characterized by a dysrhythmia with a heart rate greater than 100 beats per minute that originates i
Death A disorder characterized by a defect in tricuspid valve function or structure.
Death A disorder characterized by a dys Clarification: Grade 4
[Term deleted.[Term
Map todeleted.
CardiacMapdisorders
to Cardiac
- Other,
disorders
Deletion:
specify- (Wolff-Parkinson-White
Other,
Term specify] A disorder
syndrome),
characterized
Gradeby5.]
theDeath
presence of an access
- A disorder characterized by a sensation of marked discomfort in the ear.
[Term deleted.[Term
Map todeleted.
Otitis externa,
Map to Grade
Otitis externa.]
5.] Death
Deletion:
A disorder
Term characterized by inflammation, swelling and redness to the ou
- A disorder characterized by a sensation of marked discomfort in the external ear region.
- A disorder characterized by partiaClarification: Grade 1, 2, 3, 4
Death A disorder characterized by inflammation (physiologic response to irritation), swelling and redness to the middl
- A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking.
- A disorder characterized by a sensation as if the external world were revolving around the patient (objective ve
- A disorder characterized by dizziness, imbalance, nausea, and vision problems.
Death A disorder that occurs when characterized
Clarification:
by the
Definition
adrenal cortex does not producinge enough of the hormone c
- A disorder characterized by signs and symptoms that resemble Cushing's disease or syndrome: buffalo hump ob
- A disorder characterized by unusually late sexual maturity.
- A disorder characterized by greater growth than expected for age.
- A disorder characterized by an increase in production of parathyroid hormone by the parathyroid glands. This r
Death A disorder characterized by excessive levels of thyroid hormone in the body. Common causes include an overac
Death A disorder characterized by a decrease in production of parathyroid hormone by the parathyroid glands.
Death A disorder characterized by inflamm Addition: Term
Death A disorder characterized by a decAddition: Term
Death A disorder characterized by a decrease in production of thyroid hormone by the thyroid gland.
- A disorder characterized by unusually early development of secondary sexual features; the onset of sexual mat
- A disorder characterized by low t Addition: Term
- A disorder characterized by inappropriate masculinization occurring in a female or prepubertal male.
- A disorder characterized by visualAddition: Grade 4; Clarification: Grade 2, 3
- A disorder characterized by partiaClarification: Grade 2, 3, 4
- A disorder characterized by an areClarification: Grade 3, 4; Deletion: Grade 2
- A disorder charIf corneal ulcer is Addition: Navigational note; Clarification: Grade 1, 2, 3
- A disorder characterized by incomAddition: Grade 4; Clarification: Grade 2, 3
- - Clarification: Grade 1, 2, 3, 4
- A disorder characterized by a sensation of marked discomfort in the eye.
- A disorder characterized by impaired eyelid function.
- A disorder charAlso consider Eye dAddition: Navigational note
- A disorder charAlso consider Eye dAddition: Navigational note
- A disorder characterized by an in Clarification: Grade 1, 2, 3, 4
- A disorder charAlso consider Eye dAddition: Grade 1, Navigational note; Clarification: Grade 2, 3, 4
- A disorder characterized by an inab Clarification: Grade 2, 3, 4
- A disorder characterized by invol Clarification: Grade 2, 3, 4
- A disorder characterized by swelliClarification: Grade 1, 2, 3, 4
- A disorder characterized by fear and avoidance of light.
- A disorder characterized by the s Clarification: Grade 3, 4; Deletion: Grade 1, 2
- A disorder charIf retinal detachm Addition: Grade 1, Navigational note; Clarification: Grade 2; Deletion: Grade 3
- A disorder charIf vitreous hemorr Addition: Navigational note; Clarification: Grade 2, 3
- A disorder invoIf vitreous hemorr Addition: Navigational note; Clarification: Grade 2, 3, 4
- A disorder characterized by involvClarification: Grade 1, 2, 3, 4
- A disorder characterized by infla Clarification: Grade 1, 2, 3, 4
- A disorder charIf etiology is know Addition: Term, Navigational note
- A disorder characterized by bleedingClarification:
blood extravasation
Grade 1, 2, into
3, 4,the
Definition
vitreous humor.
- A disorder characterized by of excessive
Addition:tearing
Gradein4;the
Clarification:
eyes; it canGrade
be caused
2, 3, Definition
by overproduction of tears or imp
- A disorder characterized by swelliPrimary SOC change
- A disorder characterized by swelling of the abdomen.
- A disorder characterized by a sensation of marked discomfort in the abdominal region.
- A disorder characterized by a tearAddition: Term
Death A disorder characterized by an a Clarification: Grade 1, 2, 3
Death A disorder characterized by bleedClarification: Grade 1, 2, 3
[Grade deleted.A Map
disorder
to Anal
characterized
Ulcer,
ReportGrade
Grade
by5.]
ulceration
4 and
Death
Addition:
or inflammation
Navigationalof note;
the mucous
Clarification:
membrane
Definition;
of the
Deletion:
anus. Grade 4, 5
Death A disorder characterized by a necrClarification: Grade 3
- A disorder characterized by a sensation of marked discomfort in the anal region.
Death A disorder characterized by a narrowing of the lumen of the anal canal.
Death A disorder characterized by a circumscribed,
Clarification:inflammatory
Grade 3, Definition
and necrotic erosive lesion on the mucosal surface o
Death A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal cavity.
- To expel gas noSynonym: Burping Addition: Term, Navigational note
- A disorder characterized by subject-reported feeling of uncomfortable fullness of the abdomen.
Death A disorder characterized by blee Clarification: Grade 1, 2, 3
- A disorder characterized by inflammation of the lip.
Death A disorder characterized by accumu Addition: Term
Death A disorder characterized by infla Addition: Navigational note; Clarification: Grade 3
Death A disorder characterized by blockaClarification: Grade 3
Death A disorder characterized by a ruptClarification: Grade 2, 3
Death A disorder characterized by a narrowing of the lumen of the colon.
Grade 3, Definition
Death A disorder characterized by irregular and infrequent or difficult evacuation of the bowels.
- A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous.
Death A disorder characterized by an increase
Clarification:
in frequentcy
Grade 2,and/or
3, Definition
loose or watery bowel movements.
- A disorder characterized by reduced salivary flow in the oral cavity.
Death A disorder characterized by an Clarification: Grade 1, 2, 3
Death A disorder characterized by bloc Clarification: Grade 3
Death A disorder characterized by a rup Clarification: Grade 2, 3
Death A disorder characterized by a na Clarification: Grade 3
Grade 2, 3, Definition
- A disorder characterized by an unClarification: Grade 3
Death A disorder characterized by diffic Clarification: Grade 3
Death A disorder charIf reporting a knowAddition: Navigational note
Death A disorder characterized by an Clarification: Grade 1, 2, 3
Death A disorder characterized by blockClarification: Grade 3
- A disorder characterized by a sensation of marked discomfort in the esophageal region.
Death A disorder characterized by a nar Clarification: Grade 3
Grade 3, Definition
Death A disorder characterized by bleedClarification: Grade 3
Death A disorder characterized by infla Clarification: Grade 2, 3
- A disorder characterized by inability to control the escape of stool from the rectum.
- A disorder characterized by a discharge
Clarification:
of excessive
Definition
gas in the alimentary canal from the lower GI tract.
Death A disorder characterized by an Clarification: Grade 1, 2, 3, 4
Death A disorder characterized by bleediClarification: Grade 1, 2, 3
Death A disorder characterized by a rup Clarification: Grade 2, 3
Grade 3, Definition
Death A disorder characterized by inflammation of the stomach.
- A disorder characterized by reflu Clarification: Grade 3
Death A disorder characterized by an a Clarification: Grade 1, 2, 3, 4
- A disorder characterized by a sensation of marked discomfort in the gastrointestinal region.
- A disorder characterized by an incAddition: Grade 4; Clarification: Grade 3
- A disorder characterized by a sensation of marked discomfort in the gingival region.
- A disorder characterized by the pClarification: Grade 3
Death A disorder characterized by blockaClarification: Grade 2, 3
Death A disorder characterized by a ruptuClarification: Grade 2, 3
Death A disorder characterized by a narrowing of the lumen of the ileum.
Grade 3, Definition
Death A disorder characterized by failurAddition: Grade 1; Clarification: Grade 3
Death A disorder characterized by bleedClarification: Grade 2, 3
Death A disorder characterized by a narrowing of the lumen of the jejunum.
Grade 3, Definition
- A disorder characterized by a sensation of marked discomfort of the lip.
Death A disorder characterized by inadequate absorption of nutrients in the small intestine. Symptoms include abdom
Death A disorder characterized by ulceration
Clarification:
or inflammation
Grade 2, of
Definition
the oral mucosal.
- A disorder characterized by a queasy sensation and/or the urge to vomit.
- A disorder characterized by a burnClarification: Grade 3
- A disorder characterized by a sensation of marked discomfort in the mouth, tongue or lips.
Death A disorder characterized by a narrowing of the lumen of the pancreatic duct.
Death A disorder characterized by inflammation
Clarification:
of theGrade
pancreas
2, Definition
with no documented pancreas infection.
- A disorder in the gingival tissue around the teeth.
Death A disorder characterized by a necClarification: Grade 3
Death A disorder characterized by infla Clarification: Grade 2
- A disorder characterized by a tearAddition: Term
Clarification:
or inflammation
Definitionof the mucous membrane of the rectum.
- A disorder characterized by a sensation of marked discomfort in the rectal region.
Death A disorder characterized by a narrowing of the lumen of the rectum.
Grade 3, Definition
Death A disorder characterized by inflamClarification: Grade 3
Clarification:
or inflammation
Definitionof the mucous membrane of the small intestine.
Death A disorder characterized by blockageClarification:
of the normal
Gradeflow
3, Definition
of the intestinal contents of the small intestine.
Death A disorder characterized by a narrowing of the lumen of the small intestine.
Grade 3, Definition
- A disorder characterized by a sensation of marked discomfort in the stomach.
- A disorder characterized by a pat Clarification: Grade 3
- A disorder characterized by a change in tooth hue or tint.
- A disorder characterized by a sensation of marked discomfort in the tooth.
Also reportbyInvest
inflammation
Addition:ofNavigational
the cecum necrotizing
note; Clarification:
enterocolitis
Definition
in neutropenic patients.
Death A disorder characterized by the r Clarification: Grade 1, 2, 3, 4
Death A disorder characterized by a decrPrimary SOC change
- A disorder characterized by a sensation of cold that often marks a physiologic response to sweating after a feve
disorder
toDeath
characterized
neonatal, by
Grade
cessation
4.]
Addition:
Death
of lifeGrade
Newborn
4; Clarification:
death occurring
Definition;
duringDeletion:
the first 28
Grade
days5of life after birth.
Death A cessation of life
If death
Deathis that
due tocannot
Addition:
be attributed
Navigational
to a CTCAE
term associatedDefinition
with Grade 5.
Death Death due to dIf death is due to Addition: Term, Navigational note
- A disorder characterized by swelling due to excessive fluid accumulation in facial tissues.
- A disorder characterized by swelling due to excessive fluid accumulation in the upper or lower extremities.
- A disorder characterized by swelling due to excessive fluid accumulation in the trunk area.
- A disorder characterized by a sensation of marked discomfort in the face.
- A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient e
Death A disorder characterized by elevation of the body's temperature above the upper limit of normal.
- A disorder charSynonym: Flu, Infl Addition: Navigational note
- A disorder characterized by walking Clarification: Grade 3
- A disorder characterized by fluid Addition: Term
Death A disorder characterized by an abnormally low body temperature. Treatment is required when the body tempe
Death A disorder characterized by leakage Addition:
of a pharmacologic
Grade 1; Clarification:
or a biologic
Definition
substance from of the infusion site into th
Death A disorder characterized by an intense adverse reaction (usually immunologic) developing at the site of an injec
- A disorder charPrior to using thi Addition: Navigational note
- A disorder characterized by a feelAddition: Grade 3, Clarification: Grade 2
Death A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting mechanisms.
- A disorder characterized by swelliAddition: Grade 4
- A disorder characterized by a sensation
Clarification:
of marked
Definition
discomfort in the chest unrelated to a heart disorder.
- A disorder charPrior to using this Addition: Navigational note
Death An unexpectedIfcessation
death is due
of life
to death
Addition:
that cannot
Navigational
be attributed
to a CTCAE Definition
term associated with Grade 5.
- A disorder characterized by lymp Addition: Term
Death A disorder characterized by occluAddition: Term
Death A disorder characterized by blockage of the normal flow of the contents of the gallbladder.
- A disorder characterized by a sensation of marked discomfort in the gallbladder region.
Death A disorder characterized by a rupture in the gallbladder wall.
Death A disorder characterized by the inability
Clarification:
of the Grade
liver to3,metabolize
4, Definition
chemicals in the body. Laboratory test results
Death A disorder characterized by a necClarification: Grade 4
- A disorder characterized by a sensation of marked discomfort in the liver region.
Death A disorder characterized by a ruptClarification: Grade 3
Death A disorder characterized by an increase in blood pressure in the portal venous system.
Death A disorder characterized by the formation of a thrombus (blood clot) in the portal vein.
Death A disorder characterized by severeAddition: Term
Death A disorder charIf related to infus Addition: Navigational note; Clarification: Grade 1, 2, 3
Death A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histami
Prior to using
by resulting
thi Addition:
from loss
Navigational
of functionnote;
or tissue
Clarification:
destruction
Definition
of an organ or multiple organs,
Also considerby fever,
reporAtachypnea,
ddition: Navigational
nausea, headache,
tachycardia,
Grade
hypotension,
1, 2, 3, 4, Definition
rash, and/or hypoxi
Death A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal
Death A disorder characterized by an infAddition: Grade 2; Clarification: Grade 3
Death A disorder characterized by an in Clarification: Grade 1, 2, 3
Death A disorder characterized by acut Clarification: Grade 3
Death A disorder characterized by acuteClarification: Grade 3; Deletion: Grade 2
Death A disorder characterized by an infClarification: Grade 3
- A disorder charConsider InfectionsAddition: Term, Navigational note
Death A disorder characterized by an infe Addition: Grade 2; Clarification: Grade 3
Death A disorder characterized by an infClarification: Grade 2, 3
Death A disorder characterized by an in Clarification: Grade 2, 3
disorder
to Infections
characterized
and infestations
by an infClarification:
- Other, specify
Grade(Conjunctivitis
3; Deletion: Grade
infective),
5 Grade 5.] Death
Death A disorder charSynonym: CMV Addition: Term, Navigational note
Death A disorder characterized by an in Clarification: Grade 3
Death A disorder characterized by an infectious process involving the brain tissue.
- A disorder characterized by an infClarification: Grade 3, 4
Death A disorder charIncludes Clostridium Addition:
d Navigational note; Clarification: Grade 2, 3
Death A disorder charSynonym: EBV Addition: Term, Navigational note
- A disorder characterized by inflamm Addition: Term
- A disorder characterized by the pAddition: Term
Death A disorder characterized by the rea Addition: Term
Death A disorder characterized by a viraAddition: Grade 2; Clarification: Grade 1, 3, 4
Death A disorder characterized by the reAddition: Term
For symptomsby anand
infAddition: Grade 2;consider
no intervention, Clarification: Grade 3thoracic and mediastinal disorders: Sor
Respiratory,
Death A disorder char Addition: Navigational note; Clarification: Grade 2, 3
If infectionby
is an
dueinfectious
Addition:process
Navigational
involving
note;
theClarification:
lungs, including
Grade
pneumonia.
2, 3, Definition
Death A disorder characterized by acuteClarification: Grade 3
Death A disorder charChanges associatedAddition: Grade 1, 2, Navigational note; Clarification: Grade 3; Deletion Grade
Death A disorder characterized by an eruption
Clarification:
consisting
Grade
of 2,
papules
3, 4, Definition
(a small, raised pimple) and pustules (a small pus
Death A disorder characterized by an infAddition: Grade 1, 2; Clarification: Grade 3; Deletion Grade 2
Death A disorder charFor Grade 1 ConsideAddition: Navigational note; Clarification: Grade 2, 3
- A disorder charSynonym: Boil Addition: Navigational note; Clarification: Grade 3
- A disorder characterized by an infClarification: Grade 2
Death A disorder characterized by an in Addition: Grade 1, 2; Clarification: Grade 3; Deletion Grade 2
Death A disorder charIncludes SIRS. AlsoAddition: Grade 3, Navigational note
Death A disorder charSynonym: Herpes zAddition: Term, Navigational note
Death A disorder characterized by an infectious
Clarification:
process
Grade
involving
2, 3, Definition
the skin such as cellulitis.
- A disorder characterized by a suspAddition: Term
- A disorder characterized by the prAddition: Term
Death A disorder characterized by an in Addition: Grade 1, 2; Clarification: Grade 3; Deletion Grade 2
- A disorder charConsider InfectionsAddition: Grade 4, Navigational note; Clarification: Grade 2, 3; Primary SOC ch
Death A disorder characterized by infla Primary SOC change
- A finding of damage to the ankle Clarification: Grade 1, 2, 3
Death A finding of damage to the aorta.Addition: Grade 2; Clarification: Grade 3
Death A finding of damage to an artery. Clarification: Grade 2, 3
Death A finding of leakage of bile due Clarification: Grade 1, 3
Death A finding of leakage of urine due Clarification: Grade 1, 3
- A finding of injury of the soft tissues or bone characterized by leakage of blood into surrounding tissues.
Death A finding of impaired integrity to the anatomic site of an adverse thermal reaction. Burns can be caused by expo
Death A finding of cu Synonym: Radiation Addition: Navigational note
Death A finding of leakage due to break Clarification: Grade 1, 3
- A finding of sudden movement dow Clarification: Grade 3
Death A finding of leakage due to break Clarification: Grade 3
Death A disorder characterized by a findingClarification:
of ruptureGrade
of the2,fallopian
3, Definition;
tube wall.
Deletion: Grade 1
Death A finding of tr Prior to using this Addition: Navigational note; Clarification: Grade 3
Death A finding of disorder characterizedClarification:
by a necroticGrade
process
3, Definition
occurring in the gastrointestinal tract stoma.
- A finding of traumatic injury to t Clarification: Grade 2
Death A finding of damage to the carotidAddition: Grade 2
Death A finding of damage to the inferioAddition: Grade 1, 2, 3
Death A finding of damage to the jugularAddition: Grade 2; Clarification: Grade 3
Death A finding of damage to the superiClarification: Grade 3, 4
Death A finding of leakage of contents f Clarification: Grade 1, 3
by blockageDefinition
of the normal flow of the contents of the intestinal stoma.
Death A disorder characterized by finding Clarification:
of bleedingGrade
blood 3,
leakage
Definition
from the intestinal stoma.
Death A finding of damage to an artery Clarification: Grade 3
Death A finding of damage to the breas Clarification: Grade 3
Death A finding of damage to the heart during a surgical procedure.
Death A finding of damage to the ear duClarification: Grade 3
Death A finding of damage to the endocrClarification: Grade 3
Death A finding of damage to the gastroClarification: Grade 3
Death A finding of damage to the head aClarification: Grade 3
Death A finding of uncontrolled bleedingClarification: Grade 3
Death A finding of damage to the hepatiClarification: Grade 3
Death A finding of damage to the musculClarification: Grade 3
Death A finding of damage to the nervouClarification: Grade 3
Death A finding of damage to the eye duClarification: Grade 3
Death A finding of damage to the kidneyClarification: Grade 3
Death A finding of damage to the reprodClarification: Grade 3
Death A finding of damage to the respir Clarification: Grade 3
[Term deleted.[Term
Map todeleted.
Injury, poisoning
Map to Injury,
and procedural
poisoning
Deletion:
and
complications
Term
procedural -complications
Other, specify- (Intraoperative
Other, specify] skin
A finding
injury),
of Grade
damage
5.]toD
Death A finding of damage to the spleenClarification: Grade 3
Death A finding of damage to the urinarClarification: Grade 3
Death A finding of damage to a vein duriClarification: Grade 3
Death A finding of leakage of urine due Clarification: Grade 1, 3
Death A disorder characterized by findingClarification:
of bleedingGrade
occurring
1, 2,after
3, Definition
a surgical procedure.
Death A finding of a previously undocumented problem that occurs after a thoracic procedure.
Death A finding of protrusion of the intestinal stoma (surgically created opening on the surface of the body) above the
Death A finding of displacement of the urostomy.
Death A finding of acute skin inflammatory reaction caused by drugs, especially chemotherapeutic agents, for weeks o
- A finding of tumor-like collection Clarification: Grade 3
Death A finding of traumatic injury to the spine in which the continuity of a vertebral bone is broken.
Death A finding of narrowing of the gastrointestinal stoma (surgically created opening on the surface of the body).
- A disorder characterized by a circumscribed,
Definition and necrotic erosive lesion on the jejunal mucosal su
of bleedingGrade
from the
1, 2,trachea.
3, Definition
by blockageGrade
of the3,lumen
Definition
of the trachea.
of bleedingGrade
blood 3,
leakage
Definition
from the tracheostomy site.
Death A finding of leakage of contents Clarification: Grade 1, 3
by blockageGrade
of the1,urostomy.
Definition
of bleedingGrade
from the
3, Definition
urostomy site.
Death A finding of narrowing of the opeClarification: Grade 2
Death A disorder characterized by a ruptClarification: Grade 2, 3; Deletion: Grade 1
- A disorder thatFor systemic vacci Addition: Term, Navigational note
Death A finding of a previously undocumAddition: Grade 1; Clarification Grade 3, 4
Death A finding of damage to a vein. Clarification: Grade 3
Death A finding of dePrior to using thi Addition: Navigational note; Clarification: Grade 1, 2, 3, 4
Death A finding of se Also consider InfecAddition: Navigational note; Clarification: Grade 1, 2, 3
- A finding of traumatic injury to thClarification: Grade 1, 2, 3
Death A disorder characterized by adversPrimary SOC change
- An finding based on abnormal laboratory
Clarification:
test results
Grade 3,
in Definition
which the partial thromboplastin time is found to be gre
- A finding basedAlso consider Hepat Addition: Navigational note; Clarification: Grade 1, 2, 3, 4
- A finding based on laboratory testClarification: Grade 1, 2, 3, 4
- A finding based on laboratory test results that indicate abnormal levels of antidiuretic hormone in the blood spe
- A finding basedAlso consider Metab Addition: Term, Navigational note
- A finding based on laboratory test results that indicate an decrease in levels of corticotrophin in a blood specim
- A finding based on laboratory test results that indicate abnormal levels of gonadotrophin hormone in a blood sp
- A finding based on laboratory testAddition: Term
- A finding based on laboratory test results that indicate abnormal levels of prolactin hormone in a blood specim
- A finding basedAlso consider RespiAddition: Navigational note; Clarification: Grade 1, 2, 3
- A finding basedAlso
on laboratory
consider Cardi
testAresults
ddition:which
Navigational
that indicates
increased levels
Definition
of cardiac troponin I in a biologic
- A finding basedAlso
on laboratory
consider Cardi
testAresults
ddition:which
Navigational
that indicates
increased levels
Definition
of cardiac troponin T in a biolog
- A finding based on laboratory test results that indicate an decrease in levels of CD4 lymphocytes in a blood spec
- A finding based on laboratory test results that indicate higher than normal levels of cholesterol in a blood speci
- A finding basedAlso consider CardiAddition: Navigational note
- A finding basedAlso consider RenalAddition: Navigational note; Clarification: Grade 1, 3
- The percentageAlso consider CardiAddition: Navigational note; Clarification: Grade 3
- A finding of a cardiac dysrhythmi Clarification: Grade 1, 2, 3, 4
- A disorder characterized by Elec Addition: Term
- A finding based on laboratory testClarification: Grade 1, 2, 3, 4
- A finding basedAlso consider RespiAddition: Navigational note
- A finding based on laboratory te Clarification: Grade 1, 2, 3, 4
- A finding based on laboratory test results that indicate abnormal levels of growth hormone in a biological speci
- A finding based on laboratory test results that indicate an decrease in levels of haptoglobin in a blood specimen
- A finding based on laboratory testClarification:
results that indicate
Grade 1,increased
2, 3, Definition
levels of hemoglobin above normal in a biolog
- A finding based on laboratory testClarification: Grade 1, 2, 3
- A finding based on laboratory test results that indicate a decrease in number of lymphocytes in a blood specime
- A finding based on laboratory test results that indicate an abnormal increase in the number of lymphocytes in t
- A finding based on laboratory test results that indicate a decrease in number of neutrophils in a blood specimen
- A finding based on laboratory test results that indicate an decrease in levels of pancreatic enzymes in a biologic
- A finding based on laboratory test results that indicate a decrease in number of platelets in a blood specimen.
- A disorder charIf intervention ini Addition: Term, Navigational note
- A finding based on test results thaClarification: Grade 3, 4
- A finding base Also consider InvesAddition: Navigational note
- A finding characterized
Do not use
by Metaboli
an unexpected
Addition:orNavigational
abnormal increase
in overall body
Definition
weight; for pediatrics, greater th
- A finding characterized by a decrease in overall body weight; for pediatrics, less than the baseline growth curve
- A finding based on laboratory test results that indicate an decrease in number of white blood cells in a blood sp
Death A disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other b
Death A disorder characterized by an increase in sensitivity to the adverse effects of alcohol, which can include nasal c
Death A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other
Death A disorder characterized by a loss of appetite.
Death A disorder characterized by excessClarification: Grade 2, 3
Death A disorder characterized by an inability to properly metabolize glucose.
Death A disorder characterized by laboratory test results that indicate an elevation in the concentration of calcium (co
Death A disorder characterized by laborat Clarification: Grade 1, 2, 3, 4
Death A disorder characterized by laboraClarification: Grade 2
- A disorder characterized by laborat Addition: Term
Death A disorder characterized by laboratory test results that indicate an elevation in the concentration of magnesium
Death A disorder characterized by laboraAddition: Term
Death A disorder characterized by laboratory test results that indicate an elevation in the concentration of triglyceride
Death A disorder characterized by laborat
Clarification: Grade 1, 3, 4
Death A disorder characterized by laboratory test results that indicate a low concentration of albumin in the blood.
Death A disorder characterized by laboratory test results that indicate a low concentration of calcium (corrected for a
Death A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood.
Death A disorder characterized by laboratory test results that indicate a low concentration of magnesium in the blood
Death A disorder characterized by laboraAddition: Grade 2; Clarification: Grade 3
Death A disorder characterized by laboraClarification: Grade 1, 2, 3, 4
Death A disorder characterized by accumulation of iron in the tissues.
- A disorder charUse term InvestigaAddition: Navigational note
Death A disorder characterized by metabolic abnormalities that result from a spontaneous or therapy-related cytolysi
- A disorder characterized by a sensation of marked discomfort in a joint.
- A disorder characterized by inflamClarification: Grade 3
Death A disorder charUse new term: Musc Addition: Navigational note
Clarification:
of marked
Definition
discomfort sensation in the back region.
Clarification:
of marked
Definition
discomfort sensation in the bones.
Clarification:
of marked
Definition
discomfort sensation in the buttocks.
Death A disorder characterized by a necro
Addition: Term
Clarification:
of marked
Definition
discomfort sensation in the chest wall region.
- A disorder characterized by non-neoplastic overgrowth of bone.
Death A disorder characterized by fibrotClarification: Grade 3
Clarification:
of marked
Definition
discomfort sensation on the lateral side of the body in the re
- A disorder characterized by a reduClarification: Grade 1, 2, 3
- A disorder characterized by of stature
Clarification:
that is smaller
Definition
than normal as expected for age.
- A disorder characterized by excessi
- A disorder characterized by a decrea
- A disorder characterized by a decrease in flexibility of a cervical spine joint.
- A disorder characterized by a decrease in flexibility of a lumbar spine joint.
- A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine.
- A disorder characterized by an abnormal increase in the curvature of the lumbar portion of the spine.
- A disorder cha Synonym: Muscle Addition: Term, Navigational note
- A disorder characterized by a reduClarification: Grade 3
- A disorder characterized by a reduClarification: Grade 3
- A disorder characterized by a red Clarification: Grade 3
- A disorder characterized by of a malformation
Clarification: Grade
of the musculoskeletal
3, Definition system.
- A disorder characterized by marked discomfort sensation originating from a muscle or group of muscles.
- A disorder characterized by infla Addition: Grade 4
Clarification:
of marked
Definition
discomfort sensation in the neck area.
Death A disorder characterized by necrotAddition: Term
Death A disorder characterized by a necrotic process occurring in the bone of the mandible.
- A disorder characterized by reducClarification: Grade 1, 2, 3
Clarification:
of marked
Definition
discomfort sensation in the upper or lower extremities.
Death A disorder characterized by a necro
Death A disorder characterized by the bAddition: Term
- A disorder characterized by an inju
Addition: Term
- A disorder characterized by a malfClarification: Grade 3
Death A disorder characterized by fibrotic degeneration of the superficial soft tissues.
- A disorder characterized by lack of ability to open the mouth fully due to a decrease in the range of motion of t
- A disorder characterized by of a discrepancy
Clarification:between
Grade 3,the
Definition
lengths of the lower or upper extremities.
Death A disorder characterized by leukemia arising as a result of the mutagenic effect of chemotherapy agents.
Death A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow.
- A disorder characterized by the pAddition: Term
Death A disorder characterized by development of a malignancy most probably as a result of treatment for a previous
Death A disorder characterized by bleedAddition: Term
Clarification:
of marked
Definition
discomfort from a neoplasm that may be pressing on a nerve
- A disorder characterized by involvement
Clarification:
dysfunction
Definition
of the abducens nerve (sixth cranial nerve).
Clarification:
dysfunction
Definition
of the accessory nerve (eleventh cranial nerve).
Clarification:
dysfunction
Definition
of the acoustic nerve (eighth cranial nerve).
- A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side
- A disorder characterized by systematic and extensive loss of memory.
- A disorder charAlso consider OlfacAddition: Term, Navigational note
- A disorder characterized by the inability to speak. It may result from injuries to the vocal cords or may be functi
Death A disorder characterized by inflammation of the arachnoid membrane and adjacent subarachnoid space.
- A disorder characterized by lack of coordination of muscle movements resulting in the impairment or inability t
- A disorder characterized by regional paresthesia of the brachial plexus, marked discomfort and muscle weakne
Death A disorder characterized by a necrotic process occurring in the brain and/or spinal cord.
Death A disorder characterized by loss of cerebrospinal fluid into the surrounding tissues.
- A disorder characterized by a conspicuous change in cognitive function.
- A disorder characterized by a deterioration in the ability to concentrate.
Death A disorder characterized by a decrClarification: Grade 4
- A disorder characterized by a disturbing sensation of lightheadedness, unsteadiness, giddiness, spinning or rock
- A disorder characterized by slow and slurred speech resulting from an inability to coordinate the muscles used
- A disorder characterized by distortion of sensory perception, resulting in an abnormal and unpleasant sensation
- A disorder characterized by abnormal sensual experience with the taste of foodstuffs; it can be related to a dec
- A disorder characterized by impairment of verbal communication skills, often resulting from brain damage.
Death A disorder characterized by swelliAddition: Grade 3, 5
Death A disorder characterized by a pathologic process involving the brain.
Death A disorder cha Synonym: Restless Addition: Navigational note
- A disorder characterized by a reduction in the strength of the facial muscles.
Clarification:
dysfunction
Definition
of the facial nerve (seventh cranial nerve).
Death A disorder characterized by involvement
Clarification:
dysfunction
Definition
of the glossopharyngeal nerve (ninth cranial nerve).
Death A disorder characterized by the bAddition: Term
- A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the a
Death A disorder characterized by an abnormal increase of cerebrospinal fluid in the ventricles of the brain.
- A disorder characterized by characterized by excessive sleepiness during the daytime.
Clarification:
dysfunction
Definition
of the hypoglossal nerve (twelfth cranial nerve).
- A disorder charPrior to using this Addition: Navigational note
- [Term deleted. Map to Trochlear nerve
Deletion:
disorder.]
Term A disorder characterized by involvement of the trochlear nerv
- A disorder characterized by a decrease in consciousness characterized by mental and physical inertness.
Death A disorder characterized by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammati
- A disorder characterized by a deterioration in memory function.
Death A disorder characterized by neck stiffness, headache, and photophobia resulting from irritation of the cerebral m
- A disorder characterized by uncontrolled and purposeless movements.
Death A disorder characterized by weaknAddition: Term
- A disorder characterized by intense painful sensation along a nerve or group of nerves.
- A disorder characterized by involuntary movements of the eyeballs.
Clarification:
dysfunction
Definition
of the oculomotor nerve (third cranial nerve).
Clarification:
dysfunction
Definition
of the olfactory nerve (first cranial nerve).
- A disorder characterized by functional
Clarification:
disturbances
Definition
of sensory neurons resulting in abnormal cutaneous sensati
Also consider
by damage
NervAddition:
or dysfunction
Navigational
of thenote;
peripheral
Clarification:
motorGrade
nerves.
1, 3, Definition
disorder
to Nervous
characterized
systemby disorders
damage
Clarification:
- or
Other,
dysfunction
specify
Grade(Peripheral
of1,the
Definition;
peripheral
sensory
Deletion:
sensory
neuropathy),
Grade
nerves.
5 Grade 5.] Death
Clarification:
of marked
Definition
discomfort related to a limb or an organ that is removed from
- A disorder characterized by an episode of lightheadedness and dizziness which may precede an episode of sync
Death A disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord. Symptoms inc
Death A disorder characterized by paralysis of the recurrent laryngeal nerve.
Death A disorder characterized by headaches,
Clarification:
mentalGrade
status2,changes,
3, 4, Definition;
visual disturbances,
Deletion: Grade
and/or
1 seizures associated
Death A disorder characterized by a suddClarification: Grade 1, 3, 4
Death A disorder characterized by characterized by excessive sleepiness and drowsiness.
Death A disorder characterized by incre Clarification: Grade 4
Death A disorder characterized by pressuAddition: Term
Death A disorder characterized by a sudden
Clarification:
loss of sensory
Grade function
1, 2, 3, Definition
due to an intracranial vascular event decrease or
- A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain.
- A disorder charAlso consider NervAddition: Term, Navigational note
- A disorder charIf >24 hours, Cons Addition: Navigational note
- A disorder characterized by the uncontrolled shaking movement of the whole body or individual parts.
Clarification:
dysfunction
Definition
of the trigeminal nerve (fifth cranial nerve).
- A disorder characterized by dysfunction
Addition:of the
Termtrochlear nerve (fourth cranial nerve).
Death A disorder characterized by involvement
Clarification:
dysfunction
Definition
of the vagus nerve (tenth cranial nerve).
Death A disorder characterized by a sudden drop of the blood pressure, bradycardia, and peripheral vasodilation that
- A disorder characterized by a reduClarification: Grade 3; Primary SOC change
- A disorder characterized by a reduClarification: Grade 3; Primary SOC change
[Term deleted.[Term
Map to deleted.
Pregnancy
Maploss,
to Pregnancy
Grade 4.]Deletion:
loss.]
Fetal loss
A disorder
Term
at any characterized
gestational ageby death in utero; failure of the product of con
- A disorder characterized by inhibition of fetal growth resulting in the inability of the fetus to achieve its potenti
- Death in utero. Addition: Term
Death - Clarification: Grade 2, 3
- A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is a
- [Term deleted. Map to Pregnancy,Deletion:
puerperiumTermand perinatal conditions - Other, specify] A disorder characteriz
disorder
to Psychiatric
characterized
disorders
by a state
- Other,
Deletion:
specify
Grade
(Agitation),
5 Grade 5.] Death
- A disorder characterized by an inability to achieve orgasm.
disorder
to Psychiatric
characterized
disorders
by appreClarification:
- Other, specify (Anxiety),
Grade 3, 4;Grade
Deletion:
5.] Death
Grade 5
disorder
to Psychiatric
characterized
disorders
by a lackDeletion:
- Other, specify
Grade
(Confusion),
5 Grade 5.] Death
- A disorder characterized by sexual dysfunction characterized by a delay in climax.
Death A disorder characterized by the acClarification: Grade 3, 4
Death A disorder characterized by false Clarification: Grade 3, 4
Death A disorder characterized by melanc Clarification: Grade 4
- A disorder characterized by an exaggerated feeling of well-being which is disproportionate to events and stimu
Death A disorder characterized by a falsClarification: Grade 4
- A disorder characterized by difficulty in falling asleep and/or remaining asleep.
- A disorder characterized by a decrease in sexual desire.
- A disorder characterized by an incClarification: Grade 1; Deletion: Grade 2, 3
Death A disorder characterized by excit Clarification: Grade 3, 4
disorder
to Psychiatric
characterized
disorders
by a conClarification:
- Other, specify (Personality
Grade 4; Deletion:
change),
Grade
Grade
5 5.] Death
Death A disorder characterized by person Clarification: Grade 3, 4
- A disorder characterized by an inability to rest, relax or be still.
- A disorder characterized by thoughts of taking one's own life.
Death A disorder characterized by self-i Clarification: Grade 3
- A disorder characterized by an abn Clarification: Grade 3; Primary SOC change
Also consider
by the
InvesAddition:
acute loss ofNavigational
renal function
note;
(within
Clarification:
2 weeks)Grade
and is3,traditionally
Definition; Deletion:
classified Grade
as pre
- A disorder characterized by a sudden and involuntary contraction of the bladder wall.
Death A disorder characterized by gradual and usually permanent loss of kidney function resulting in renal failure.
Death A disorder characterized by inflamClarification: Grade 3, 4
- A disorder charIf associated with Addition: Term, Navigational note
- A disorder characterized by laboraAddition: Term
Death A disorder characterized by laboraClarification: Grade 3, 4
- A disorder charReport underlying Addition: Navigational note
Death A disorder characterized by symptAddition: Term
- A disorder char24-hour urine colleAddition: Navigational note; Clarification: Grade 1, 2, 3
Death - Clarification: Grade 2, 3
Death A disorder characterized by the formation
Clarification:
of crystals/kidney
Grade 3, 4, Definition
stones in the pelvis of the kidney.
- A disorder characterized by paroxysmal
Clarification:
and severe
Definition
flank marked discomfort radiating to the inguinal area. Ofte
- A disorder characterized by urination at short intervals.
- A disorder characterized by inability to control the flow of urine from the bladder.
Death A disorder characterized by accumu Clarification: Grade 3
Death A disorder characterized by blockaClarification: Grade 1, 2, 3
- A disorder characterized by a sensation of marked discomfort in the urinary tract.
- A disorder characterized by a sudden compelling urge to urinate.
- A disorder characterized by a change in the color of the urine.
- A disorder characterized by the a Addition: Term
- A disorder characterized by labor Addition: Grade 2; Deletion: Grade 3
- A disorder characterized by underdevelopment of the breast.
Clarification:
of marked
Definition
discomfort sensation in the breast region.
- A disorder characterized by abnormally painful abdominal cramps during menses.
- A disorder characterized by painful or difficult coitus.
- A disorder characterized by problems related to ejaculation. This category includes premature, delayed, retrogr
- A disorder characterized by the persistent or recurrent inability to achieve or to maintain an erection during sex
- A disorder characterized by blockaClarification: Grade 1, 2, 3
[Term deleted.[Term
Map to deleted.
Reproductive
Map tosystem
Reproductive
andDeletion:
breast
system
disorders
Term
and breast
- Other,
disorders
specify- (Fallopian
Other, specify]
tube stenosis),
A disorderGrade
characterized
5.] Deathby a
[Term deleted.[Term
Map to deleted.
Reproductive
Map tosystem
grade 5and
Reproductive
Deletion:
breast disorders
Term
system- Other,
and breast
specify
disorders
(Female- Other,
genitalspecify]
tract fistula),
A disorder
Gradecharacter
5.] Deat
- A disorder characterized by the development of secondary female sex characteristics in males due to extrinsic f
- A disorder characterized by swelling due to an excessive accumulation of fluid in the genitals.
- A disorder characterized by excesClarification: Grade 1
Death A disorder characterized by the prClarification: Grade 3
Also consider
by irregular
Rep Addition:
a change
Navigational
in cycle ornote;
duration
Clarification:
of menses Grade
from1,baseline.
2, Definition; Deletion: Gra
- A disorder characterized by disturbances of milk secretion. It is not necessarily related to pregnancy that is obse
Death A disorder characterized by abno Clarification: Grade 3
- A disorder characterized by a malformation of the nipple.
- A disorder characterized by a de Clarification: Grade 1; Deletion: Grade 2, 3
Death A disorder characterized by bleedClarification: Grade 1, 2, 3, 4
Death A disorder characterized by tearinClarification: Grade 3
Clarification:
of marked
Gradediscomfort
2, Definition;
sensation
Deletion:
in one
Grade
side1,of3the abdomen between m
disorder
to Reproductive
characterizedsystem
by a redu
andDeletion:
breast disorders
Grade 4, -5Other, specify (Pelvic floor muscle weakness), Grade 5.] D
Clarification:
of marked
Definition
discomfort sensation in the pelvis.
Clarification:
of marked
Definition
discomfort sensation in the penis.
- A disorder characterized by a sensation of marked discomfort in the area between the genital organs and the a
- A disorder characterized by prematureAddition:
ovarian
Gradefailure
2; Clarification:
before the Definition;
age of 40. Symptoms
Deletion: Grade
may include
3 hot flashes,
- A disorder characterized by compre Clarification: Grade 1, 2, 3
- A disorder characterized by a sensation of marked discomfort in the prostate gland.
Clarification:
of marked
Definition
discomfort sensation in the scrotal area.
- A disorder characterized by blockClarification: Grade 1, 2, 3
disorder
to Reproductive
characterized
Also consider
system
by abnormal
ReprAddition:
and breast
function
disorders:
Navigational
or appearance
Other,
note;
specify
Clarification:
involvement
(Testicular
Grade
of the
disorder),
testis.
2, 3, Definition;
Grade 5.] Deletion:
Death Gra
Death A disorder characterized by bleediClarification: Grade 1, 2, 3, 4
- A disorder characterized by a sensation of marked discomfort in the testis.
- A disorder characterized by a sensation of marked discomfort in the uterus.
- A disorder characterized by vaginal secretions. Mucus produced by the cervical glands is discharged from the va
- A disorder characterized by an uncomfortable feeling of itching and burning in the vagina.
disorder
to Reproductive
characterizedsystem
by inflandClarification:
breast disorders:
GradeOpther,
4; Deletion:
specify
Grade
(Vaginal
5 inflammation), Grade 5.] Death
- A disorder characterized by a sensation of marked discomfort in the vagina.
Death A disorder characterized by a ruptClarification: Grade 2, 3; Deletion: Grade 1
Death A disorder characterized by a narrowing of the vaginal canal.
- [Term deleted. Map to Reproductive Deletion:
systemTerm
and breast disorders - Other, specify] A disorder characterized by i
Death A disorder characterized by progressive and life-threatening pulmonary distress in the absence of an underlying
- A disorder characterized by an inflammation of the nasal mucous membranes caused by an IgE-mediated respo
Death A disorder characterized by cessation of breathing.
Death A disorder characterized by inhalation of solids or liquids into the lungs.
Death A disorder characterized by the coClarification: Grade 3
Death A disorder characterized by blockage of a bronchus passage, most often by bronchial secretions and exudates.
Death A disorder characterized by a narrowing of the bronchial tube.
Death A disorder characterized by a sudClarification: Grade 3
Death A disorder characterized by milky Clarification: Grade 2
- A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in v
Death A disorder characterized by an uncomfortable sensation of difficulty breathing.
- A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glo
- A disorder characterized by harsh and raspy voice arising from or spreading to the larynx.
Death A disorder characterized by a decrease in the level of oxygen in the body.
Death A disorder characterized by swelling due to an excessive accumulation of fluid in the larynx.
- A disorder characterized by an inflammation involving the larynx.
Clarification:
or an inflammation
Grade 2, Definition
involving the mucous membrane of the larynx.
Death A disorder characterized by an unClarification: Grade 2
Death A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords.
- A disorder characterized by obstruction of the nasal passage due to mucosal edema.
- A disorder characterized by a senAddition: Term
Death A disorder characterized by an ulceration
Clarification:
or inflammation
Grade 2, Definition
involving the mucous membrane of the pharynx.
Clarification:
of marked
Definition
discomfort sensation in the pharyngolaryngeal region.
Death A disorder characterized by bleediClarification: Grade 3, 4
Clarification:
of marked
Definition
discomfort sensation in the pleura.
Death A disorder characterized by inflammation focally or diffusely affecting the lung parenchyma.
Death A disorder characterized by abnorm Clarification: Grade 2
- A disorder characterized by excessive mucous secretion in the back of the nasal cavity or throat, causing sore th
- A disorder characterized by expectorated secretions upon coughing.
Death A disorder characterized by accumulation of fluid in the lung tissues that causes a disturbance of the gas exchan
Death A disorder characterized by the reClarification: Grade 1, 2, 3
Death A disorder characterized by an incClarification: Grade 3
Death A disorder characterized by impairedClarification:
gas exchangeDefinition
by the respiratory system resulting in hypoxemia and a decr
Death A disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal fa
- A disorder characterized by excesAddition: Term
Death A disorder characterized by involvement of the paranasal sinuses.
Death A disorder characterized by cessatClarification: Grade 3
- A disorder characterized by the involuntary expulsion of air from the nose.
- A disorder characterized by of marked
Clarification:
discomfort
Definition
in the throat
Death A disorder characterized by a high pitched breathing sound due to laryngeal or upper airway obstruction.
Death A disorder characterized by an inflammation
Clarification:orDefinition
ulceration involving the mucous membrane of the trachea.
Death A disorder characterized by a nar Clarification: Grade 2, 3
- A disorder characterized by a change in the sound and/or speed of the voice.
Death A disorder characterized by a high-pitched, whistling sound during breathing. It results from the narrowing or o
Clarification:
of marked
Definition;
discomfort
Primary
in the
SOC face,
change
between the eyes, or upper teeth ori
- A disorder characterized by a decrease in density of hair compared to normal for a given individual at a given ag
- A disorder characterized by an abnormal body smell resulting from the growth of bacteria on the body.
Death A disorder charIf infectious, consi Addition: Navigational note
- A disorder characterized by flaky and dull skin; the pores are generally fine, the texture is a papery thin texture.
- A disorder characterized by skin wAddition: Term
Death A disorder characterized by target lesions (a pink-red ring around a pale center).
Death A disorder characterized by generalized inflammatory erythema and exfoliation. The inflammatory process invo
- A disorder characterized by shrinking of adipose tissue.
- A disorder characterized by change Addition: Term
- A disorder characterized by a chanAddition: Term
- A disorder characterized by the presence of excess hair growth in women in anatomic sites where growth is con
Synonym: by Night
excessive
sweAddition:
perspiration
Navigational
sweating.
note; Clarification: Grade 3, Definition
- A disorder characterized by a thicAddition: Term
- A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body reg
Death A disorder characterized by reduced sweating.
- A disorder characterized by hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneou
- A disorder characterized by a chanAddition: Term
- A disorder characterized by a chanClarification: Grade 1
- A disorder characterized by loss of all or a portion of the nail.
- A disorder characterized by vertical or horizontal ridges on the nails.
Clarification:
of marked
Definition
discomfort sensation in the skin.
- A disorder characterized by redness,
Clarification:
marked discomfort,
Grade 2, 3,swelling,
Definition
and tingling in the palms of the hands or the
Death A disorder characterized by an increase in sensitivity of the skin to light.
- A disorder characterized by an intClarification: Grade 2, 3
- A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddis
Death A disorder characterized by an eruClarification: Grade 2, 3, 4
- A disorder characterized by the pClarification: Grade 2, 3
Clarification:
of marked
Definition
discomfort sensation in the skin covering the top and the ba
- A disorder characterized by the degeneration and thinning of the epidermis and dermis.
- A disorder characterized by darkening of the skin due to excessive melanin deposition.
- A disorder characterized by loss ofClarification:
skin pigmentDefinition
(e.g., vitiligo).
Death A disorder characterized by an areClarification: Grade 3
Definition and necrotic erosive lesion on the skin.
Death A disorder characterized by less Clarification: Grade 3
- A disorder characterized by air in Addition: Term
- A disorder characterized by local Clarification: Grade 2
Death A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thoug
- A disorder characterized by an itchy skin eruption characterized by wheals with pale interiors and well-defined
- [Term deleted. Map to PrematureDeletion:
menopause.]TermA disorder characterized by the permanent cessation of mense
Death A disorder charConsider Nervous sy Addition: Term, Navigational note
Death A disorder characterized by leakagAddition: Grade 1
- A disorder characterized by episodic
Clarification:
reddeningGradeof the1,skin,
2, Definition
especially face, neck, or chest.
Death A disorder characterized by a localClarification: Grade 3
- A disorder characterized by an uncomfortable and temporary sensation of intense body warmth, flushing, some
Death A disorder characterized by a pathological
Clarification:
increase
Gradein1,blood
2, 3, pressure;
4, Definition
a repeatedly elevation in the blood press
Death A disorder characterized by a blo Clarification: Grade 3, 4
Death A disorder characterized by the loClarification: Grade 3
- A disorder characterized by excessive fluid collection in tissues that causes swelling.
- A disorder characterized by a cystClarification: Grade 3
Death A disorder characterized by impairClarification: Grade 2, 3
- A disorder characterized by inflammation of the wall of a vein.
- A disorder characterized by a blood clot and inflammation involving a superficial vein of the extremities.
Death A disorder characterized by obstruction of the blood flow in the superior vena cava. Signs and symptoms includ
Death A disorder charConsider Nervous sAddition: Navigational note; Clarification: Grade 1, 2, 3, 4
Death A disorder characterized by inflamClarification: Grade 4
atopoietic elements.
mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of
>38.3 degrees C (101 degrees F) or a sustained temperature of >=38 degrees C (100.4 degrees F) for more than one hour
number of white blood cells in the blood.
Typically, this is accompanied by cessation of the pumping function of the heart.
or the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval great
ade 2, 3, Definition
R interval prior to the blocking of an atrial impulse. This is the result of intermittent failure of atrial electrical impulse conduction through t
n interruption of blood supply to the area.
ful beating of the heart.
due to inflammation.
collection of blood or fluid in the pericardium.
tective sac around the heart).
beats per minute that originates in the sinus node.

swelling and redness to the middle ear.
g around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo).
ase or syndrome: buffalo hump obesity, striations, adiposity, hypertension, diabetes, and osteoporosis, usually due to exogenous corticost
e by the parathyroid glands. This results in hypercalcemia (abnormally high levels of calcium in the blood).
Common causes include an overactive thyroid gland or thyroid hormone overdose.
by the parathyroid glands.
he thyroid gland.
features; the onset of sexual maturation begins usually before age 8 for girls and before age 9 for boys.
le or prepubertal male.
cation: Grade 2, 3, 4
cation: Grade 2; Deletion: Grade 3, 4
efinition; Deletion: Grade 4, 5
e peritoneal cavity.
s of the abdomen.
the bowels.
d, discolored and/or porous.
estinal region.
testine. Symptoms include abdominal marked discomfort, bloating and diarrhea.
ongue or lips.
response to sweating after a fever.

Deletion: Grade 5
e upper or lower extremities.
e trunk area.
ed inability to summon sufficient energy to accomplish daily activities.

pper limit of normal.
is required when the body temperature is 35C (95F) or below.
) developing at the site of an injection.
y and clotting mechanisms.
e gallbladder.
e release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents wi
ade 1, 2, 3, 4, Definition
n proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antige
ification: Grade 3; Deletion Grade 2
Deletion Grade 2
Deletion Grade 2
Deletion Grade 2
Deletion Grade 2
Deletion Grade 2
cation: Grade 2, 3; Primary SOC change
d into surrounding tissues.
ction. Burns can be caused by exposure to chemicals, direct heat, electricity, flames and radiation. The extent of damage depends on the le
he surface of the body) above the abdominal surface.
motherapeutic agents, for weeks or months following radiotherapy. The inflammatory reaction is confined to the previously irradiated skin
l bone is broken.
ng on the surface of the body).
ade 1, 2, 3, 4
ade 1, 2, 3, 4
ade 1, 2, 3, 4
tidiuretic hormone in the blood specimen.
ade 1, 2, 3, 4
f corticotrophin in a blood specimen.
adotrophin hormone in a blood specimen.
lactin hormone in a blood specimen.
f CD4 lymphocytes in a blood specimen.

els of cholesterol in a blood specimen.
wth hormone in a biological specimen.

f haptoglobin in a blood specimen.
of lymphocytes in a blood specimen.

n the number of lymphocytes in the blood, effusions or bone marrow.
of neutrophils in a blood specimen.
f pancreatic enzymes in a biological specimen.
of platelets in a blood specimen.
ss than the baseline growth curve.

r of white blood cells in a blood specimen.
ntration) of the blood and other body tissues.
alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and headaches.
entration) of the blood and other body tissues.
n the concentration of calcium (corrected for albumin) in blood.
n the concentration of magnesium in the blood.

n the concentration of triglyceride concentration in the blood.
ration of albumin in the blood.

ration of calcium (corrected for albumin) in the blood.
ration of glucose in the blood.
ration of magnesium in the blood.
neous or therapy-related cytolysis of tumor cells.
acic portion of the spine.

bar portion of the spine.
muscle or group of muscles.

crease in the range of motion of the muscles of mastication.
ct of chemotherapy agents.
on by the bone marrow.
result of treatment for a previously existing malignancy.
d inability to stay still; this is a side effect of some psychotropic drugs.
o the vocal cords or may be functional (psychogenic).

jacent subarachnoid space.
ng in the impairment or inability to perform voluntary activities.
d discomfort and muscle weakness, and limited movement in the arm or hand.
diness, giddiness, spinning or rocking.

y to coordinate the muscles used in speech.
bnormal and unpleasant sensation.
odstuffs; it can be related to a decrease in the sense of smell.
resulting from brain damage.
of the head, not confined to the area of distribution of any nerve.
ventricles of the brain.
ntal and physical inertness.

f necrotic foci without inflammation.
ng from irritation of the cerebral meninges.
h may precede an episode of syncope.

of the spinal cord. Symptoms include an increase in the muscle tone in the lower extremities, hyperreflexia, positive Babinski and a decre
on: Grade 1
fficient blood supply to the brain.
body or individual parts.
, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase in the stimulation of the vagus nerve.
of the fetus to achieve its potential weight.

of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation.
roportionate to events and stimuli.
ade 3, Definition; Deletion: Grade 1, 2
ction resulting in renal failure.

ludes premature, delayed, retrograde and painful ejaculation.
to maintain an erection during sexual activity.
teristics in males due to extrinsic factors.

in the genitals.
ade 1, 2, Definition; Deletion: Grade 3

y related to pregnancy that is observed in females and can be observed in males.
ween the genital organs and the anus.

Deletion: Grade 3
ade 2, 3, Definition; Deletion: Grade 5

al glands is discharged from the vagina naturally, especially during the childbearing years.
n the vagina.
ss in the absence of an underlying pulmonary condition, usually following major trauma or surgery.
caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eye
onchial secretions and exudates.
f the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound.
ary opening and closing of the glottis. This is attributed to a spasm of the diaphragm.
o the larynx.
in the larynx.
e vocal cords.
g parenchyma.
al cavity or throat, causing sore throat and/or coughing.
es a disturbance of the gas exchange that may lead to respiratory failure.
sions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid.
r upper airway obstruction.
It results from the narrowing or obstruction of the respiratory airways.
for a given individual at a given age and body location.

h of bacteria on the body.
e texture is a papery thin texture.
on. The inflammatory process involves > 90% of the body surface area.
natomic sites where growth is considered to be a secondary male characteristic and under androgen control (beard, moustache, chest, ab
ade 3, Definition
of normal in a particular body region, for a particular age or race.
at the site of multiple subcutaneous injections of insulin.

rane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow colo
of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.
h pale interiors and well-defined red margins.
ense body warmth, flushing, sometimes accompanied by sweating upon cooling.
ial vein of the extremities.

cava. Signs and symptoms include swelling and cyanosis of the face, neck, and upper arms, cough, orthopnea and headache.
ade 1, 2, 3, 4
as the body is depleted of platelets and coagulation factors.
on of the PR interval greater than 200 milliseconds.
ulse conduction through the atrioventricular (AV) node to the ventricles.

ue to exogenous corticosteroids.
e. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death.
ation of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort an
damage depends on the length and intensity of exposure and time until provision of treatment.
e previously irradiated skin and the symptoms disappear after the removal of the pharmaceutical agent.
sitive Babinski and a decrease in fine motor coordination.
n of the vagus nerve.

mbranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea and itching.
ard, moustache, chest, abdomen).
me a brownish-yellow color.
nd headache.
may lead to death.
hest marked discomfort and dyspnea.
v4.0 MedDRA Code v4.0 MedDRA SOC v4.0 CTCAE Term Grade/Definition
10002272 Blood and lymphatic systeAnemia 1
10002272 Blood and lymphatic systeAnemia Definition
10005329 Blood and lymphatic systeBlood and lymphatic system
1
2
3
4
5
10048580 Blood and lymphatic systeBone marrow hypocellular1
10048580 Blood and lymphatic systeBone marrow hypocellularDefinition
10013442 Blood and lymphatic systeDisseminated intravascula2
10013442 Blood and lymphatic systeDisseminated intravasculaDefinition
10016288 Blood and lymphatic systeFebrile neutropenia 3
10016288 Blood and lymphatic systeFebrile neutropenia Definition
10019491 Blood and lymphatic systeHemolysis 1
10019491 Blood and lymphatic systeHemolysis Definition
10019515 Blood and lymphatic systeHemolytic uremic syndro 3
10019515 Blood and lymphatic systeHemolytic uremic syndro Definition
10024378 Blood and lymphatic systeLeukocytosis 3
10024378 Blood and lymphatic systeLeukocytosis Definition
10025182 Blood and lymphatic systeLymph node pain 1
10025182 Blood and lymphatic systeLymph node pain Definition
10041633 Blood and lymphatic systeSpleen disorder 1
10041633 Blood and lymphatic systeSpleen disorder Definition
10043648 Blood and lymphatic systeThrombotic thrombocytop1
10043648 Blood and lymphatic systeThrombotic thrombocytopDefinition
10051592 Cardiac disorders Acute coronary syndrome2
10051592 Cardiac disorders Acute coronary syndromeDefinition
10061589 Cardiac disorders Aortic valve disease 1
10061589 Cardiac disorders Aortic valve disease Definition
10003586 Cardiac disorders Asystole 1
10003586 Cardiac disorders Asystole Definition
10003658 Cardiac disorders Atrial fibrillation 1
10003658 Cardiac disorders Atrial fibrillation Definition
10003662 Cardiac disorders Atrial flutter 1
10003662 Cardiac disorders Atrial flutter Definition
10003673 Cardiac disorders Atrioventricular block com2
10003673 Cardiac disorders Atrioventricular block comDefinition
10003674 Cardiac disorders Atrioventricular block firs 1
10003674 Cardiac disorders Atrioventricular block firs 2
10003674 Cardiac disorders Atrioventricular block firs Definition
10007515 Cardiac disorders Cardiac arrest 4
10007515 Cardiac disorders Cardiac arrest 5
10007515 Cardiac disorders Cardiac arrest Definition
10007541 Cardiac disorders Cardiac disorders - Other, 1
10008481 Cardiac disorders Chest pain - cardiac 1
10008481 Cardiac disorders Chest pain - cardiac Definition
10010276 Cardiac disorders Conduction disorder 1
10010276 Cardiac disorders Conduction disorder Definition
10010783 Cardiac disorders Constrictive pericarditis 3
10010783 Cardiac disorders Constrictive pericarditis Definition
10019279 Cardiac disorders Heart failure 1
10019279 Cardiac disorders Heart failure Definition
10069501 Cardiac disorders Left ventricular systolic d 3
10069501 Cardiac disorders Left ventricular systolic d Definition
10061532 Cardiac disorders Mitral valve disease 1
10061532 Cardiac disorders Mitral valve disease Definition
10027786 Cardiac disorders Mobitz (type) II atrioventr1
10027786 Cardiac disorders Mobitz (type) II atrioventrDefinition
10027787 Cardiac disorders Mobitz type I 1
10027787 Cardiac disorders Mobitz type I Definition
10028596 Cardiac disorders Myocardial infarction 2
10028596 Cardiac disorders Myocardial infarction Definition
10028606 Cardiac disorders Myocarditis 2
10028606 Cardiac disorders Myocarditis Definition
10033557 Cardiac disorders Palpitations 1
10033557 Cardiac disorders Palpitations 2
10033557 Cardiac disorders Palpitations Definition
10034040 Cardiac disorders Paroxysmal atrial tachycar1
10034040 Cardiac disorders Paroxysmal atrial tachycarDefinition
10034474 Cardiac disorders Pericardial effusion 2
10034474 Cardiac disorders Pericardial effusion Definition
10053565 Cardiac disorders Pericardial tamponade 4
10053565 Cardiac disorders Pericardial tamponade 5
10053565 Cardiac disorders Pericardial tamponade Definition
10034484 Cardiac disorders Pericarditis 1
10034484 Cardiac disorders Pericarditis Definition
10061541 Cardiac disorders Pulmonary valve disease 1
10061541 Cardiac disorders Pulmonary valve disease Definition
10038748 Cardiac disorders Restrictive cardiomyopath3
10038748 Cardiac disorders Restrictive cardiomyopathDefinition
10058597 Cardiac disorders Right ventricular dysfunct 1
10058597 Cardiac disorders Right ventricular dysfunct Definition
10040639 Cardiac disorders Sick sinus syndrome 1
10040639 Cardiac disorders Sick sinus syndrome Definition
10040741 Cardiac disorders Sinus bradycardia 1
10040741 Cardiac disorders Sinus bradycardia Definition
10040752 Cardiac disorders Sinus tachycardia 1
10040752 Cardiac disorders Sinus tachycardia Definition
10042604 Cardiac disorders Supraventricular tachycar 1
10042604 Cardiac disorders Supraventricular tachycar Definition
10061389 Cardiac disorders Tricuspid valve disease 1
10061389 Cardiac disorders Tricuspid valve disease Definition
10047281 Cardiac disorders Ventricular arrhythmia 1
10047281 Cardiac disorders Ventricular arrhythmia Definition
10047290 Cardiac disorders Ventricular fibrillation 4
10047290 Cardiac disorders Ventricular fibrillation 5
10047290 Cardiac disorders Ventricular fibrillation Definition
10047302 Cardiac disorders Ventricular tachycardia 2
10047302 Cardiac disorders Ventricular tachycardia Definition
10048015 Cardiac disorders Wolff-Parkinson-White s 1
10048015 Cardiac disorders Wolff-Parkinson-White s Definition
10010331 Congenital, familial and geCongenital, familial and ge1
10013993 Ear and labyrinth disorderEar and labyrinth disorders1
10014020 Ear and labyrinth disorderEar pain 1
10014020 Ear and labyrinth disorderEar pain Definition
10065837 Ear and labyrinth disorderExternal ear inflammation1
10065837 Ear and labyrinth disorderExternal ear inflammationDefinition
10065785 Ear and labyrinth disorderExternal ear pain 1
10065785 Ear and labyrinth disorderExternal ear pain Definition
10019245 Ear and labyrinth disorderHearing impaired 1
10019245 Ear and labyrinth disorderHearing impaired Definition
10065838 Ear and labyrinth disorderMiddle ear inflammation 1
10065838 Ear and labyrinth disorderMiddle ear inflammation Definition
10043882 Ear and labyrinth disorderTinnitus 1
10043882 Ear and labyrinth disorderTinnitus Definition
10047340 Ear and labyrinth disorderVertigo 1
10047340 Ear and labyrinth disorderVertigo Definition
10047386 Ear and labyrinth disorderVestibular disorder 2
10047386 Ear and labyrinth disorderVestibular disorder 3
10047386 Ear and labyrinth disorderVestibular disorder Definition
10001367 Endocrine disorders Adrenal insufficiency 1
10001367 Endocrine disorders Adrenal insufficiency Definition
10011655 Endocrine disorders Cushingoid 1
10011655 Endocrine disorders Cushingoid Definition
10012205 Endocrine disorders Delayed puberty 2
10012205 Endocrine disorders Delayed puberty 3
10012205 Endocrine disorders Delayed puberty Definition
10014698 Endocrine disorders Endocrine disorders - Othe1
10018746 Endocrine disorders Growth accelerated 2
10018746 Endocrine disorders Growth accelerated Definition
10020705 Endocrine disorders Hyperparathyroidism 1
10020705 Endocrine disorders Hyperparathyroidism 2
10020705 Endocrine disorders Hyperparathyroidism Definition
10020850 Endocrine disorders Hyperthyroidism 1
10020850 Endocrine disorders Hyperthyroidism Definition
10021041 Endocrine disorders Hypoparathyroidism 1
10021041 Endocrine disorders Hypoparathyroidism Definition
10021114 Endocrine disorders Hypothyroidism 1
10021114 Endocrine disorders Hypothyroidism Definition
10058084 Endocrine disorders Precocious puberty 1
10058084 Endocrine disorders Precocious puberty 2
10058084 Endocrine disorders Precocious puberty Definition
10047488 Endocrine disorders Virilization 1
10047488 Endocrine disorders Virilization 2
10047488 Endocrine disorders Virilization Definition
10005886 Eye disorders Blurred vision 1
10005886 Eye disorders Blurred vision Definition
10007739 Eye disorders Cataract 1
10007739 Eye disorders Cataract Definition
10010741 Eye disorders Conjunctivitis 1
10010741 Eye disorders Conjunctivitis Definition
10048492 Eye disorders Corneal ulcer 2
10048492 Eye disorders Corneal ulcer Definition
10013774 Eye disorders Dry eye 1
10013774 Eye disorders Dry eye Definition
10015829 Eye disorders Extraocular muscle paresis1
10015829 Eye disorders Extraocular muscle paresisDefinition
10015919 Eye disorders Eye disorders - Other, spec1
10015958 Eye disorders Eye pain 1
10015958 Eye disorders Eye pain Definition
10061145 Eye disorders Eyelid function disorder 1
10061145 Eye disorders Eyelid function disorder Definition
10016757 Eye disorders Flashing lights 1
10016757 Eye disorders Flashing lights Definition
10016778 Eye disorders Floaters 1
10016778 Eye disorders Floaters Definition
10018304 Eye disorders Glaucoma 1
10018304 Eye disorders Glaucoma Definition
10023332 Eye disorders Keratitis 2
10023332 Eye disorders Keratitis Definition
10029404 Eye disorders Night blindness 1
10029404 Eye disorders Night blindness Definition
10061322 Eye disorders Optic nerve disorder 1
10061322 Eye disorders Optic nerve disorder Definition
10033703 Eye disorders Papilledema 1
10033703 Eye disorders Papilledema Definition
10034960 Eye disorders Photophobia 1
10034960 Eye disorders Photophobia Definition
10038848 Eye disorders Retinal detachment 1
10038848 Eye disorders Retinal detachment Definition
10038897 Eye disorders Retinal tear 3
10038897 Eye disorders Retinal tear Definition
10038901 Eye disorders Retinal vascular disorder 2
10038901 Eye disorders Retinal vascular disorder 3
10038901 Eye disorders Retinal vascular disorder Definition
10038923 Eye disorders Retinopathy 1
10038923 Eye disorders Retinopathy Definition
10061510 Eye disorders Scleral disorder 1
10061510 Eye disorders Scleral disorder Definition
10046851 Eye disorders Uveitis 1
10046851 Eye disorders Uveitis Definition
10047656 Eye disorders Vitreous hemorrhage 1
10047656 Eye disorders Vitreous hemorrhage Definition
10047848 Eye disorders Watering eyes 1
10047848 Eye disorders Watering eyes Definition
10000060 Gastrointestinal disorders Abdominal distension 1
10000060 Gastrointestinal disorders Abdominal distension Definition
10000081 Gastrointestinal disorders Abdominal pain 1
10000081 Gastrointestinal disorders Abdominal pain Definition
10002156 Gastrointestinal disorders Anal fistula 1
10002156 Gastrointestinal disorders Anal fistula Definition
10055226 Gastrointestinal disorders Anal hemorrhage 1
10055226 Gastrointestinal disorders Anal hemorrhage Definition
10065721 Gastrointestinal disorders Anal mucositis 4
10065721 Gastrointestinal disorders Anal mucositis Definition
10065722 Gastrointestinal disorders Anal necrosis 3
10065722 Gastrointestinal disorders Anal necrosis Definition
10002167 Gastrointestinal disorders Anal pain 1
10002167 Gastrointestinal disorders Anal pain Definition
10002176 Gastrointestinal disorders Anal stenosis 1
10002176 Gastrointestinal disorders Anal stenosis Definition
10002180 Gastrointestinal disorders Anal ulcer 1
10002180 Gastrointestinal disorders Anal ulcer Definition
10003445 Gastrointestinal disorders Ascites 1
10003445 Gastrointestinal disorders Ascites Definition
10005265 Gastrointestinal disorders Bloating 1
10005265 Gastrointestinal disorders Bloating 2
10005265 Gastrointestinal disorders Bloating Definition
10065747 Gastrointestinal disorders Cecal hemorrhage 1
10065747 Gastrointestinal disorders Cecal hemorrhage Definition
10008417 Gastrointestinal disorders Cheilitis 1
10008417 Gastrointestinal disorders Cheilitis Definition
10009887 Gastrointestinal disorders Colitis 1
10009887 Gastrointestinal disorders Colitis Definition
10009995 Gastrointestinal disorders Colonic fistula 1
10009995 Gastrointestinal disorders Colonic fistula Definition
10009998 Gastrointestinal disorders Colonic hemorrhage 1
10009998 Gastrointestinal disorders Colonic hemorrhage Definition
10010000 Gastrointestinal disorders Colonic obstruction 1
10010000 Gastrointestinal disorders Colonic obstruction Definition
10010001 Gastrointestinal disorders Colonic perforation 2
10010001 Gastrointestinal disorders Colonic perforation Definition
10010004 Gastrointestinal disorders Colonic stenosis 1
10010004 Gastrointestinal disorders Colonic stenosis Definition
10010006 Gastrointestinal disorders Colonic ulcer 1
10010006 Gastrointestinal disorders Colonic ulcer Definition
10010774 Gastrointestinal disorders Constipation 1
10010774 Gastrointestinal disorders Constipation Definition
10012318 Gastrointestinal disorders Dental caries 1
10012318 Gastrointestinal disorders Dental caries Definition
10012727 Gastrointestinal disorders Diarrhea 1
10012727 Gastrointestinal disorders Diarrhea Definition
10013781 Gastrointestinal disorders Dry mouth 1
10013781 Gastrointestinal disorders Dry mouth Definition
10013828 Gastrointestinal disorders Duodenal fistula 1
10013828 Gastrointestinal disorders Duodenal fistula Definition
10055242 Gastrointestinal disorders Duodenal hemorrhage 1
10055242 Gastrointestinal disorders Duodenal hemorrhage Definition
10013830 Gastrointestinal disorders Duodenal obstruction 1
10013830 Gastrointestinal disorders Duodenal obstruction Definition
10013832 Gastrointestinal disorders Duodenal perforation 2
10013832 Gastrointestinal disorders Duodenal perforation Definition
10050094 Gastrointestinal disorders Duodenal stenosis 1
10050094 Gastrointestinal disorders Duodenal stenosis Definition
10013836 Gastrointestinal disorders Duodenal ulcer 1
10013836 Gastrointestinal disorders Duodenal ulcer Definition
10013946 Gastrointestinal disorders Dyspepsia 1
10013946 Gastrointestinal disorders Dyspepsia Definition
10013950 Gastrointestinal disorders Dysphagia 1
10013950 Gastrointestinal disorders Dysphagia Definition
10014893 Gastrointestinal disorders Enterocolitis 1
10014893 Gastrointestinal disorders Enterocolitis Definition
10062570 Gastrointestinal disorders Enterovesical fistula 1
10062570 Gastrointestinal disorders Enterovesical fistula Definition
10065851 Gastrointestinal disorders Esophageal fistula 1
10065851 Gastrointestinal disorders Esophageal fistula Definition
10015384 Gastrointestinal disorders Esophageal hemorrhage 1
10015384 Gastrointestinal disorders Esophageal hemorrhage Definition
10065727 Gastrointestinal disorders Esophageal necrosis 3
10065727 Gastrointestinal disorders Esophageal necrosis Definition
10015387 Gastrointestinal disorders Esophageal obstruction 1
10015387 Gastrointestinal disorders Esophageal obstruction Definition
10015388 Gastrointestinal disorders Esophageal pain 1
10015388 Gastrointestinal disorders Esophageal pain Definition
10055472 Gastrointestinal disorders Esophageal perforation 2
10055472 Gastrointestinal disorders Esophageal perforation Definition
10015448 Gastrointestinal disorders Esophageal stenosis 1
10015448 Gastrointestinal disorders Esophageal stenosis Definition
10015451 Gastrointestinal disorders Esophageal ulcer 1
10015451 Gastrointestinal disorders Esophageal ulcer Definition
10015453 Gastrointestinal disorders Esophageal varices hemor2
10015453 Gastrointestinal disorders Esophageal varices hemorDefinition
10015461 Gastrointestinal disorders Esophagitis 1
10015461 Gastrointestinal disorders Esophagitis Definition
10016296 Gastrointestinal disorders Fecal incontinence 1
10016296 Gastrointestinal disorders Fecal incontinence Definition
10016766 Gastrointestinal disorders Flatulence 1
10016766 Gastrointestinal disorders Flatulence 2
10016766 Gastrointestinal disorders Flatulence Definition
10065713 Gastrointestinal disorders Gastric fistula 1
10065713 Gastrointestinal disorders Gastric fistula Definition
10017789 Gastrointestinal disorders Gastric hemorrhage 1
10017789 Gastrointestinal disorders Gastric hemorrhage Definition
10051886 Gastrointestinal disorders Gastric necrosis 3
10051886 Gastrointestinal disorders Gastric necrosis Definition
10017815 Gastrointestinal disorders Gastric perforation 2
10017815 Gastrointestinal disorders Gastric perforation Definition
10061970 Gastrointestinal disorders Gastric stenosis 1
10061970 Gastrointestinal disorders Gastric stenosis Definition
10017822 Gastrointestinal disorders Gastric ulcer 1
10017822 Gastrointestinal disorders Gastric ulcer Definition
10017853 Gastrointestinal disorders Gastritis 1
10017853 Gastrointestinal disorders Gastritis Definition
10066874 Gastrointestinal disorders Gastroesophageal reflux d1
10066874 Gastrointestinal disorders Gastroesophageal reflux dDefinition
10017947 Gastrointestinal disorders Gastrointestinal disorders 1
10017877 Gastrointestinal disorders Gastrointestinal fistula 1
10017877 Gastrointestinal disorders Gastrointestinal fistula Definition
10017999 Gastrointestinal disorders Gastrointestinal pain 1
10017999 Gastrointestinal disorders Gastrointestinal pain Definition
10018043 Gastrointestinal disorders Gastroparesis 1
10018043 Gastrointestinal disorders Gastroparesis Definition
10018286 Gastrointestinal disorders Gingival pain 1
10018286 Gastrointestinal disorders Gingival pain Definition
10060640 Gastrointestinal disorders Hemorrhoidal hemorrhag 1
10060640 Gastrointestinal disorders Hemorrhoidal hemorrhag Definition
10019611 Gastrointestinal disorders Hemorrhoids 1
10019611 Gastrointestinal disorders Hemorrhoids Definition
10065728 Gastrointestinal disorders Ileal fistula 1
10065728 Gastrointestinal disorders Ileal fistula Definition
10055287 Gastrointestinal disorders Ileal hemorrhage 1
10055287 Gastrointestinal disorders Ileal hemorrhage Definition
10065730 Gastrointestinal disorders Ileal obstruction 1
10065730 Gastrointestinal disorders Ileal obstruction Definition
10021305 Gastrointestinal disorders Ileal perforation 2
10021305 Gastrointestinal disorders Ileal perforation Definition
10021307 Gastrointestinal disorders Ileal stenosis 1
10021307 Gastrointestinal disorders Ileal stenosis Definition
10021309 Gastrointestinal disorders Ileal ulcer 1
10021309 Gastrointestinal disorders Ileal ulcer Definition
10021328 Gastrointestinal disorders Ileus 2
10021328 Gastrointestinal disorders Ileus Definition
10055291 Gastrointestinal disorders Intra-abdominal hemorrh 2
10055291 Gastrointestinal disorders Intra-abdominal hemorrh Definition
10065719 Gastrointestinal disorders Jejunal fistula 1
10065719 Gastrointestinal disorders Jejunal fistula Definition
10055300 Gastrointestinal disorders Jejunal hemorrhage 1
10055300 Gastrointestinal disorders Jejunal hemorrhage Definition
10065732 Gastrointestinal disorders Jejunal obstruction 1
10065732 Gastrointestinal disorders Jejunal obstruction Definition
10023174 Gastrointestinal disorders Jejunal perforation 2
10023174 Gastrointestinal disorders Jejunal perforation Definition
10023176 Gastrointestinal disorders Jejunal stenosis 1
10023176 Gastrointestinal disorders Jejunal stenosis Definition
10023177 Gastrointestinal disorders Jejunal ulcer 1
10023177 Gastrointestinal disorders Jejunal ulcer Definition
10024561 Gastrointestinal disorders Lip pain 1
10024561 Gastrointestinal disorders Lip pain Definition
10051746 Gastrointestinal disorders Lower gastrointestinal he 1
10051746 Gastrointestinal disorders Lower gastrointestinal he Definition
10025476 Gastrointestinal disorders Malabsorption 2
10025476 Gastrointestinal disorders Malabsorption Definition
10028130 Gastrointestinal disorders Mucositis oral 1
10028130 Gastrointestinal disorders Mucositis oral Definition
10028813 Gastrointestinal disorders Nausea 1
10028813 Gastrointestinal disorders Nausea Definition
10029957 Gastrointestinal disorders Obstruction gastric 1
10029957 Gastrointestinal disorders Obstruction gastric Definition
10065720 Gastrointestinal disorders Oral cavity fistula 1
10065720 Gastrointestinal disorders Oral cavity fistula Definition
10054520 Gastrointestinal disorders Oral dysesthesia 1
10054520 Gastrointestinal disorders Oral dysesthesia Definition
10030980 Gastrointestinal disorders Oral hemorrhage 1
10030980 Gastrointestinal disorders Oral hemorrhage Definition
10031009 Gastrointestinal disorders Oral pain 1
10031009 Gastrointestinal disorders Oral pain Definition
10065703 Gastrointestinal disorders Pancreatic duct stenosis 1
10065703 Gastrointestinal disorders Pancreatic duct stenosis Definition
10049192 Gastrointestinal disorders Pancreatic fistula 1
10049192 Gastrointestinal disorders Pancreatic fistula Definition
10033626 Gastrointestinal disorders Pancreatic hemorrhage 1
10033626 Gastrointestinal disorders Pancreatic hemorrhage Definition
10058096 Gastrointestinal disorders Pancreatic necrosis 3
10058096 Gastrointestinal disorders Pancreatic necrosis Definition
10033645 Gastrointestinal disorders Pancreatitis 2
10033645 Gastrointestinal disorders Pancreatitis Definition
10034536 Gastrointestinal disorders Periodontal disease 1
10034536 Gastrointestinal disorders Periodontal disease Definition
10065704 Gastrointestinal disorders Peritoneal necrosis 3
10065704 Gastrointestinal disorders Peritoneal necrosis Definition
10036774 Gastrointestinal disorders Proctitis 1
10036774 Gastrointestinal disorders Proctitis Definition
10038062 Gastrointestinal disorders Rectal fistula 1
10038062 Gastrointestinal disorders Rectal fistula Definition
10038064 Gastrointestinal disorders Rectal hemorrhage 1
10038064 Gastrointestinal disorders Rectal hemorrhage Definition
10063190 Gastrointestinal disorders Rectal mucositis 1
10063190 Gastrointestinal disorders Rectal mucositis Definition
10065709 Gastrointestinal disorders Rectal necrosis 3
10065709 Gastrointestinal disorders Rectal necrosis Definition
10065707 Gastrointestinal disorders Rectal obstruction 1
10065707 Gastrointestinal disorders Rectal obstruction Definition
10038072 Gastrointestinal disorders Rectal pain 1
10038072 Gastrointestinal disorders Rectal pain Definition
10038073 Gastrointestinal disorders Rectal perforation 2
10038073 Gastrointestinal disorders Rectal perforation Definition
10038079 Gastrointestinal disorders Rectal stenosis 1
10038079 Gastrointestinal disorders Rectal stenosis Definition
10038080 Gastrointestinal disorders Rectal ulcer 1
10038080 Gastrointestinal disorders Rectal ulcer Definition
10038981 Gastrointestinal disorders Retroperitoneal hemorrha2
10038981 Gastrointestinal disorders Retroperitoneal hemorrhaDefinition
10056681 Gastrointestinal disorders Salivary duct inflammatio 1
10056681 Gastrointestinal disorders Salivary duct inflammatio Definition
10039411 Gastrointestinal disorders Salivary gland fistula 1
10039411 Gastrointestinal disorders Salivary gland fistula Definition
10065710 Gastrointestinal disorders Small intestinal mucositis 1
10065710 Gastrointestinal disorders Small intestinal mucositis Definition
10041101 Gastrointestinal disorders Small intestinal obstructio1
10041101 Gastrointestinal disorders Small intestinal obstructioDefinition
10041103 Gastrointestinal disorders Small intestinal perforatio2
10041103 Gastrointestinal disorders Small intestinal perforatioDefinition
10062263 Gastrointestinal disorders Small intestinal stenosis 1
10062263 Gastrointestinal disorders Small intestinal stenosis Definition
10041133 Gastrointestinal disorders Small intestine ulcer 1
10041133 Gastrointestinal disorders Small intestine ulcer Definition
10042112 Gastrointestinal disorders Stomach pain 1
10042112 Gastrointestinal disorders Stomach pain Definition
10044030 Gastrointestinal disorders Tooth development disord1
10044030 Gastrointestinal disorders Tooth development disordDefinition
10044031 Gastrointestinal disorders Tooth discoloration 1
10044031 Gastrointestinal disorders Tooth discoloration Definition
10044055 Gastrointestinal disorders Toothache 1
10044055 Gastrointestinal disorders Toothache Definition
10045271 Gastrointestinal disorders Typhlitis 3
10045271 Gastrointestinal disorders Typhlitis Definition
10055356 Gastrointestinal disorders Upper gastrointestinal h 1
10055356 Gastrointestinal disorders Upper gastrointestinal h Definition
10047700 Gastrointestinal disorders Vomiting 1
10047700 Gastrointestinal disorders Vomiting Definition
10008531 General disorders and admi Chills 1
10008531 General disorders and admi Chills Definition
10011912 General disorders and admi Death neonatal 5
10011912 General disorders and admi Death neonatal Definition
10011914 General disorders and admi Death NOS 5
10011914 General disorders and admi Death NOS Definition
10014222 General disorders and admi Edema face 1
10014222 General disorders and admi Edema face Definition
10050068 General disorders and admi Edema limbs 1
10050068 General disorders and admi Edema limbs Definition
10058720 General disorders and admi Edema trunk 1
10058720 General disorders and admi Edema trunk Definition
10016059 General disorders and admi Facial pain 1
10016059 General disorders and admi Facial pain 2
10016059 General disorders and admi
Facial pain 3
Facial pain Definition
Fatigue 1
Fatigue 2
Fatigue 3
Fatigue Definition
Fever 1
Fever 2
Fever 3
Fever 4
Fever 5
Fever Definition
Flu like symptoms 1
Flu like symptoms 2
Flu like symptoms 3
Flu like symptoms Definition
Gait disturbance 1
Gait disturbance 2
Gait disturbance 3
Gait disturbance Definition
General disorders and admi 1
Hypothermia 2
Hypothermia 3
Hypothermia 4
Hypothermia 5
Hypothermia Definition
Infusion related reaction 1
Infusion related reaction Definition
Infusion site extravasation2
Infusion site extravasationDefinition
Injection site reaction 1
Injection site reaction Definition
Irritability 1
Irritability 2
Irritability 3
Irritability Definition
Localized edema 1
Localized edema 2
Localized edema 3
Localized edema Definition
Malaise 1
Malaise 2
Malaise Definition
Multi-organ failure 3
Multi-organ failure Definition
Neck edema 1
Neck edema 2
Neck edema 3
Neck edema Definition
Non-cardiac chest pain 1
Non-cardiac chest pain Definition
Pain 1
Pain 2
Pain 3
Pain Definition
Sudden death NOS 5
Sudden death NOS Definition
10051341 Hepatobiliary disorders Bile duct stenosis 1
10051341 Hepatobiliary disorders Bile duct stenosis Definition
10004665 Hepatobiliary disorders Biliary fistula 2
10004665 Hepatobiliary disorders Biliary fistula Definition
10008612 Hepatobiliary disorders Cholecystitis 2
10008612 Hepatobiliary disorders Cholecystitis Definition
10017631 Hepatobiliary disorders Gallbladder fistula 1
10017631 Hepatobiliary disorders Gallbladder fistula Definition
10059446 Hepatobiliary disorders Gallbladder necrosis 4
10059446 Hepatobiliary disorders Gallbladder necrosis 5
10059446 Hepatobiliary disorders Gallbladder necrosis Definition
10017636 Hepatobiliary disorders Gallbladder obstruction 1
10017636 Hepatobiliary disorders Gallbladder obstruction Definition
10017638 Hepatobiliary disorders Gallbladder pain 1
10017638 Hepatobiliary disorders Gallbladder pain Definition
10017639 Hepatobiliary disorders Gallbladder perforation 4
10017639 Hepatobiliary disorders Gallbladder perforation 5
10017639 Hepatobiliary disorders Gallbladder perforation Definition
10019663 Hepatobiliary disorders Hepatic failure 3
10019663 Hepatobiliary disorders Hepatic failure Definition
10019678 Hepatobiliary disorders Hepatic hemorrhage 1
10019678 Hepatobiliary disorders Hepatic hemorrhage Definition
10019692 Hepatobiliary disorders Hepatic necrosis 4
10019692 Hepatobiliary disorders Hepatic necrosis 5
10019692 Hepatobiliary disorders Hepatic necrosis Definition
10019705 Hepatobiliary disorders Hepatic pain 1
10019705 Hepatobiliary disorders Hepatic pain Definition
10019805 Hepatobiliary disorders Hepatobiliary disorders - O1
10034405 Hepatobiliary disorders Perforation bile duct 3
10034405 Hepatobiliary disorders Perforation bile duct Definition
10036200 Hepatobiliary disorders Portal hypertension 2
10036200 Hepatobiliary disorders Portal hypertension Definition
10036206 Hepatobiliary disorders Portal vein thrombosis 2
10036206 Hepatobiliary disorders Portal vein thrombosis Definition
10001718 Immune system disorders Allergic reaction 1
10001718 Immune system disorders Allergic reaction Definition
10002218 Immune system disorders Anaphylaxis 3
10002218 Immune system disorders Anaphylaxis Definition
10061664 Immune system disorders Autoimmune disorder 1
10061664 Immune system disorders Autoimmune disorder Definition
10052015 Immune system disorders Cytokine release syndrom1
10052015 Immune system disorders Cytokine release syndromDefinition
10021428 Immune system disorders Immune system disorders 1-
10040400 Immune system disorders Serum sickness 1
10040400 Immune system disorders Serum sickness Definition
10056519 Infections and infestationsAbdominal infection 3
10056519 Infections and infestationsAbdominal infection Definition
10061640 Infections and infestationsAnorectal infection 1
10061640 Infections and infestationsAnorectal infection Definition
10003011 Infections and infestationsAppendicitis 3
10003011 Infections and infestationsAppendicitis Definition
10003012 Infections and infestationsAppendicitis perforated 3
10003012 Infections and infestationsAppendicitis perforated Definition
10065744 Infections and infestationsArteritis infective 3
10065744 Infections and infestationsArteritis infective Definition
10061695 Infections and infestationsBiliary tract infection 3
10061695 Infections and infestationsBiliary tract infection Definition
10005047 Infections and infestationsBladder infection 2
10005047 Infections and infestationsBladder infection Definition
10061017 Infections and infestationsBone infection 3
10061017 Infections and infestationsBone infection Definition
10006259 Infections and infestationsBreast infection 2
10006259 Infections and infestationsBreast infection Definition
10055078 Infections and infestationsBronchial infection 2
10055078 Infections and infestationsBronchial infection Definition
10007810 Infections and infestationsCatheter related infection2
10007810 Infections and infestationsCatheter related infectionDefinition
10065761 Infections and infestationsCecal infection 3
10065761 Infections and infestationsCecal infection Definition
10008330 Infections and infestationsCervicitis infection 2
10008330 Infections and infestationsCervicitis infection Definition
10010742 Infections and infestationsConjunctivitis infective 5
10010742 Infections and infestationsConjunctivitis infective Definition
10061788 Infections and infestationsCorneal infection 2
10061788 Infections and infestationsCorneal infection Definition
10065765 Infections and infestationsCranial nerve infection 3
10065765 Infections and infestationsCranial nerve infection Definition
10064687 Infections and infestationsDevice related infection 3
10064687 Infections and infestationsDevice related infection Definition
10065752 Infections and infestationsDuodenal infection 2
10065752 Infections and infestationsDuodenal infection Definition
10014594 Infections and infestationsEncephalitis infection 3
10014594 Infections and infestationsEncephalitis infection Definition
10014621 Infections and infestationsEncephalomyelitis infectio3
10014621 Infections and infestationsEncephalomyelitis infectioDefinition
10014678 Infections and infestationsEndocarditis infective 3
10014678 Infections and infestationsEndocarditis infective Definition
10014801 Infections and infestationsEndophthalmitis 2
10014801 Infections and infestationsEndophthalmitis Definition
10058838 Infections and infestationsEnterocolitis infectious 2
10058838 Infections and infestationsEnterocolitis infectious Definition
10058804 Infections and infestationsEsophageal infection 2
10058804 Infections and infestationsEsophageal infection Definition
10015929 Infections and infestationsEye infection 2
10015929 Infections and infestationsEye infection Definition
10062632 Infections and infestationsGallbladder infection 3
10062632 Infections and infestationsGallbladder infection Definition
10018784 Infections and infestationsGum infection 1
10018784 Infections and infestationsGum infection Definition
10056522 Infections and infestationsHepatic infection 3
10056522 Infections and infestationsHepatic infection Definition
10019799 Infections and infestationsHepatitis viral 1
10019799 Infections and infestationsHepatitis viral Definition
10021881 Infections and infestationsInfections and infestations1
10021918 Infections and infestationsInfective myositis 2
10021918 Infections and infestationsInfective myositis Definition
10023216 Infections and infestationsJoint infection 2
10023216 Infections and infestationsJoint infection Definition
10023424 Infections and infestationsKidney infection 3
10023424 Infections and infestationsKidney infection Definition
10023874 Infections and infestationsLaryngitis 2
10023874 Infections and infestationsLaryngitis Definition
10065755 Infections and infestationsLip infection 1
10065755 Infections and infestationsLip infection Definition
10061229 Infections and infestationsLung infection 2
10061229 Infections and infestationsLung infection Definition
10050823 Infections and infestationsLymph gland infection 2
10050823 Infections and infestationsLymph gland infection Definition
10057483 Infections and infestationsMediastinal infection 3
10057483 Infections and infestationsMediastinal infection Definition
10027199 Infections and infestationsMeningitis 3
10027199 Infections and infestationsMeningitis Definition
10065764 Infections and infestationsMucosal infection 1
10065764 Infections and infestationsMucosal infection Definition
10061304 Infections and infestationsNail infection 1
10061304 Infections and infestationsNail infection Definition
10033072 Infections and infestationsOtitis externa 2
10033072 Infections and infestationsOtitis externa Definition
10033078 Infections and infestationsOtitis media 2
10033078 Infections and infestationsOtitis media Definition
10055005 Infections and infestationsOvarian infection 2
10055005 Infections and infestationsOvarian infection Definition
10051741 Infections and infestationsPancreas infection 3
10051741 Infections and infestationsPancreas infection Definition
10069138 Infections and infestationsPapulopustular rash 1
10069138 Infections and infestationsPapulopustular rash Definition
10034016 Infections and infestationsParonychia 1
10034016 Infections and infestationsParonychia Definition
10058674 Infections and infestationsPelvic infection 2
10058674 Infections and infestationsPelvic infection Definition
10061912 Infections and infestationsPenile infection 2
10061912 Infections and infestationsPenile infection Definition
10051472 Infections and infestationsPeriorbital infection 2
10051472 Infections and infestationsPeriorbital infection Definition
10065766 Infections and infestationsPeripheral nerve infection2
10065766 Infections and infestationsPeripheral nerve infectionDefinition
10057262 Infections and infestationsPeritoneal infection 3
10057262 Infections and infestationsPeritoneal infection Definition
10034835 Infections and infestationsPharyngitis 2
10034835 Infections and infestationsPharyngitis Definition
10056627 Infections and infestationsPhlebitis infective 2
10056627 Infections and infestationsPhlebitis infective Definition
10061351 Infections and infestationsPleural infection 2
10061351 Infections and infestationsPleural infection Definition
10050662 Infections and infestationsProstate infection 2
10050662 Infections and infestationsProstate infection Definition
10037888 Infections and infestationsRash pustular 2
10037888 Infections and infestationsRash pustular 3
10037888 Infections and infestationsRash pustular Definition
10059827 Infections and infestationsRhinitis infective 2
10059827 Infections and infestationsRhinitis infective Definition
10039413 Infections and infestationsSalivary gland infection 2
10039413 Infections and infestationsSalivary gland infection Definition
10062156 Infections and infestationsScrotal infection 2
10062156 Infections and infestationsScrotal infection Definition
10040047 Infections and infestationsSepsis 4
10040047 Infections and infestationsSepsis 5
10040047 Infections and infestationsSepsis Definition
10040753 Infections and infestationsSinusitis 2
10040753 Infections and infestationsSinusitis Definition
10040872 Infections and infestationsSkin infection 1
10040872 Infections and infestationsSkin infection Definition
10065771 Infections and infestationsSmall intestine infection 2
10065771 Infections and infestationsSmall intestine infection Definition
10062255 Infections and infestationsSoft tissue infection 2
10062255 Infections and infestationsSoft tissue infection Definition
10062112 Infections and infestationsSplenic infection 3
10062112 Infections and infestationsSplenic infection Definition
10064505 Infections and infestationsStoma site infection 1
10064505 Infections and infestationsStoma site infection Definition
10048762 Infections and infestationsTooth infection 2
10048762 Infections and infestationsTooth infection Definition
10044302 Infections and infestationsTracheitis 2
10044302 Infections and infestationsTracheitis Definition
10046300 Infections and infestationsUpper respiratory infectio2
10046300 Infections and infestationsUpper respiratory infectioDefinition
10052298 Infections and infestationsUrethral infection 2
10052298 Infections and infestationsUrethral infection Definition
10046571 Infections and infestationsUrinary tract infection 2
10046571 Infections and infestationsUrinary tract infection Definition
10062233 Infections and infestationsUterine infection 2
10062233 Infections and infestationsUterine infection Definition
10046914 Infections and infestationsVaginal infection 2
10046914 Infections and infestationsVaginal infection Definition
10065772 Infections and infestationsVulval infection 1
10065772 Infections and infestationsVulval infection Definition
10048038 Infections and infestationsWound infection 2
10048038 Infections and infestationsWound infection Definition
10002544 Injury, poisoning and procAnkle fracture 1
10002544 Injury, poisoning and procAnkle fracture Definition
10002899 Injury, poisoning and procAortic injury 3
10002899 Injury, poisoning and procAortic injury Definition
10003162 Injury, poisoning and procArterial injury 1
10003162 Injury, poisoning and procArterial injury Definition
10050458 Injury, poisoning and procBiliary anastomotic leak 1
10050458 Injury, poisoning and procBiliary anastomotic leak Definition
10065802 Injury, poisoning and procBladder anastomotic leak 1
10065802 Injury, poisoning and procBladder anastomotic leak Definition
10006504 Injury, poisoning and procBruising 1
10006504 Injury, poisoning and procBruising 2
10006504 Injury, poisoning and procBruising Definition
10006634 Injury, poisoning and procBurn 1
10006634 Injury, poisoning and procBurn Definition
10061103 Injury, poisoning and procDermatitis radiation 1
10061103 Injury, poisoning and procDermatitis radiation Definition
10065961 Injury, poisoning and procEsophageal anastomotic l 1
10065961 Injury, poisoning and procEsophageal anastomotic l Definition
10016173 Injury, poisoning and procFall 1
10016173 Injury, poisoning and procFall Definition
10065788 Injury, poisoning and procFallopian tube anastomoti1
10065788 Injury, poisoning and procFallopian tube anastomotiDefinition
10065790 Injury, poisoning and procFallopian tube perforation1
10065790 Injury, poisoning and procFallopian tube perforationDefinition
10017076 Injury, poisoning and procFracture 1
10017076 Injury, poisoning and procFracture Definition
10065893 Injury, poisoning and procGastric anastomotic leak 1
10065893 Injury, poisoning and procGastric anastomotic leak Definition
10065879 Injury, poisoning and procGastrointestinal anastomot1
10065879 Injury, poisoning and procGastrointestinal anastomotDefinition
10065712 Injury, poisoning and procGastrointestinal stoma nec2
10065712 Injury, poisoning and procGastrointestinal stoma necDefinition
10020100 Injury, poisoning and procHip fracture 2
10020100 Injury, poisoning and procHip fracture Definition
10022161 Injury, poisoning and procInjury to carotid artery 3
10022161 Injury, poisoning and procInjury to carotid artery Definition
10022213 Injury, poisoning and procInjury to inferior vena cav 4
10022213 Injury, poisoning and procInjury to inferior vena cav 5
10022213 Injury, poisoning and procInjury to inferior vena cav Definition
10065849 Injury, poisoning and procInjury to jugular vein 3
10065849 Injury, poisoning and procInjury to jugular vein Definition
10022356 Injury, poisoning and procInjury to superior vena ca 1
10022356 Injury, poisoning and procInjury to superior vena ca Definition
10022117 Injury, poisoning and procInjury, poisoning and proc1
10059095 Injury, poisoning and procIntestinal stoma leak 1
10059095 Injury, poisoning and procIntestinal stoma leak Definition
10059094 Injury, poisoning and procIntestinal stoma obstructi 2
10059094 Injury, poisoning and procIntestinal stoma obstructi Definition
10049468 Injury, poisoning and procIntestinal stoma site bleed1
10049468 Injury, poisoning and procIntestinal stoma site bleedDefinition
10065826 Injury, poisoning and procIntraoperative arterial inju1
10065826 Injury, poisoning and procIntraoperative arterial injuDefinition
10065831 Injury, poisoning and procIntraoperative breast injur1
10065831 Injury, poisoning and procIntraoperative breast injurDefinition
10065843 Injury, poisoning and procIntraoperative cardiac inju3
10065843 Injury, poisoning and procIntraoperative cardiac injuDefinition
10065844 Injury, poisoning and procIntraoperative ear injury 1
10065844 Injury, poisoning and procIntraoperative ear injury Definition
10065834 Injury, poisoning and procIntraoperative endocrine i1
10065834 Injury, poisoning and procIntraoperative endocrine iDefinition
10065825 Injury, poisoning and procIntraoperative gastrointest1
10065825 Injury, poisoning and procIntraoperative gastrointestDefinition
10065842 Injury, poisoning and procIntraoperative head and ne1
10065842 Injury, poisoning and procIntraoperative head and neDefinition
10055298 Injury, poisoning and procIntraoperative hemorrhag3
10055298 Injury, poisoning and procIntraoperative hemorrhagDefinition
10065827 Injury, poisoning and procIntraoperative hepatobiliar1
10065827 Injury, poisoning and procIntraoperative hepatobiliarDefinition
10065829 Injury, poisoning and procIntraoperative musculoskel1
10065829 Injury, poisoning and procIntraoperative musculoskelDefinition
10065830 Injury, poisoning and procIntraoperative neurological1
10065830 Injury, poisoning and procIntraoperative neurologicalDefinition
10065841 Injury, poisoning and procIntraoperative ocular injur1
10065841 Injury, poisoning and procIntraoperative ocular injurDefinition
10065845 Injury, poisoning and procIntraoperative renal injury1
10065845 Injury, poisoning and procIntraoperative renal injuryDefinition
10065840 Injury, poisoning and procIntraoperative reproductive1
10065840 Injury, poisoning and procIntraoperative reproductiveDefinition
10065832 Injury, poisoning and procIntraoperative respiratory 1
10065832 Injury, poisoning and procIntraoperative respiratory Definition
10065846 Injury, poisoning and procIntraoperative skin injury 1
10065846 Injury, poisoning and procIntraoperative skin injury Definition
10065847 Injury, poisoning and procIntraoperative splenic inju2
10065847 Injury, poisoning and procIntraoperative splenic injuDefinition
10065828 Injury, poisoning and procIntraoperative urinary inju1
10065828 Injury, poisoning and procIntraoperative urinary injuDefinition
10065848 Injury, poisoning and procIntraoperative venous inju1
10065848 Injury, poisoning and procIntraoperative venous injuDefinition
10065803 Injury, poisoning and procKidney anastomotic leak 1
10065803 Injury, poisoning and procKidney anastomotic leak Definition
10065891 Injury, poisoning and procLarge intestinal anastomot1
10065891 Injury, poisoning and procLarge intestinal anastomotDefinition
10050457 Injury, poisoning and procPancreatic anastomotic le 1
10050457 Injury, poisoning and procPancreatic anastomotic le Definition
10065705 Injury, poisoning and procPharyngeal anastomotic le1
10065705 Injury, poisoning and procPharyngeal anastomotic leDefinition
10055322 Injury, poisoning and procPostoperative hemorrhag 1
10055322 Injury, poisoning and procPostoperative hemorrhag Definition
10056745 Injury, poisoning and procPostoperative thoracic pr 2
10056745 Injury, poisoning and procPostoperative thoracic pr Definition
10065745 Injury, poisoning and procProlapse of intestinal sto 1
10065745 Injury, poisoning and procProlapse of intestinal sto Definition
10065822 Injury, poisoning and procProlapse of urostomy 1
10065822 Injury, poisoning and procProlapse of urostomy Definition
10037767 Injury, poisoning and procRadiation recall reaction 1
10037767 Injury, poisoning and procRadiation recall reaction Definition
10065894 Injury, poisoning and procRectal anastomotic leak 1
10065894 Injury, poisoning and procRectal anastomotic leak Definition
10040102 Injury, poisoning and procSeroma 1
10040102 Injury, poisoning and procSeroma Definition
10065892 Injury, poisoning and procSmall intestinal anastomot1
10065892 Injury, poisoning and procSmall intestinal anastomotDefinition
10065897 Injury, poisoning and procSpermatic cord anastomoti1
10065897 Injury, poisoning and procSpermatic cord anastomotiDefinition
10041569 Injury, poisoning and procSpinal fracture 1
10041569 Injury, poisoning and procSpinal fracture Definition
10065898 Injury, poisoning and procStenosis of gastrointestin 2
10065898 Injury, poisoning and procStenosis of gastrointestin Definition
10042127 Injury, poisoning and procStomal ulcer 1
10042127 Injury, poisoning and procStomal ulcer Definition
10062548 Injury, poisoning and procTracheal hemorrhage 1
10062548 Injury, poisoning and procTracheal hemorrhage Definition
10044291 Injury, poisoning and procTracheal obstruction 1
10044291 Injury, poisoning and procTracheal obstruction Definition
10065749 Injury, poisoning and procTracheostomy site bleedin1
10065749 Injury, poisoning and procTracheostomy site bleedinDefinition
10065814 Injury, poisoning and procUreteric anastomotic leak 1
10065814 Injury, poisoning and procUreteric anastomotic leak Definition
10065815 Injury, poisoning and procUrethral anastomotic leak1
10065815 Injury, poisoning and procUrethral anastomotic leakDefinition
10065882 Injury, poisoning and procUrostomy leak 1
10065882 Injury, poisoning and procUrostomy leak Definition
10065883 Injury, poisoning and procUrostomy obstruction 1
10065883 Injury, poisoning and procUrostomy obstruction Definition
10065748 Injury, poisoning and procUrostomy site bleeding 1
10065748 Injury, poisoning and procUrostomy site bleeding Definition
10065885 Injury, poisoning and procUrostomy stenosis 2
10065885 Injury, poisoning and procUrostomy stenosis Definition
10065886 Injury, poisoning and procUterine anastomotic leak 1
10065886 Injury, poisoning and procUterine anastomotic leak Definition
10046810 Injury, poisoning and procUterine perforation 1
10046810 Injury, poisoning and procUterine perforation Definition
10065887 Injury, poisoning and procVaginal anastomotic leak 1
10065887 Injury, poisoning and procVaginal anastomotic leak Definition
10065888 Injury, poisoning and procVas deferens anastomotic 1
10065888 Injury, poisoning and procVas deferens anastomotic Definition
10062169 Injury, poisoning and procVascular access complicat 2
10062169 Injury, poisoning and procVascular access complicat Definition
10047228 Injury, poisoning and procVenous injury 1
10047228 Injury, poisoning and procVenous injury Definition
10053692 Injury, poisoning and procWound complication 1
10053692 Injury, poisoning and procWound complication Definition
10048031 Injury, poisoning and procWound dehiscence 1
10048031 Injury, poisoning and procWound dehiscence Definition
10048049 Injury, poisoning and procWrist fracture 1
10048049 Injury, poisoning and procWrist fracture Definition
10000636 Investigations Activated partial thrombo1
10000636 Investigations Activated partial thromboDefinition
10001551 Investigations Alanine aminotransferase 1
10001551 Investigations Alanine aminotransferase Definition
10001675 Investigations Alkaline phosphatase incr 1
10001675 Investigations Alkaline phosphatase incr Definition
10003481 Investigations Aspartate aminotransferas1
10003481 Investigations Aspartate aminotransferasDefinition
10005332 Investigations Blood antidiuretic hormo 1
10005332 Investigations Blood antidiuretic hormo Definition
10005364 Investigations Blood bilirubin increased 1
10005364 Investigations Blood bilirubin increased Definition
10005452 Investigations Blood corticotrophin decr 1
10005452 Investigations Blood corticotrophin decr Definition
10005561 Investigations Blood gonadotrophin abn 1
10005561 Investigations Blood gonadotrophin abn Definition
10005778 Investigations Blood prolactin abnormal 1
10005778 Investigations Blood prolactin abnormal 2
10005778 Investigations Blood prolactin abnormal Definition
10065906 Investigations Carbon monoxide diffusing1
10065906 Investigations Carbon monoxide diffusingDefinition
10007612 Investigations Cardiac troponin I increas 1
10007612 Investigations Cardiac troponin I increas 3
10007612 Investigations Cardiac troponin I increas Definition
10007613 Investigations Cardiac troponin T increa 1
10007613 Investigations Cardiac troponin T increa 3
10007613 Investigations Cardiac troponin T increa Definition
10007839 Investigations CD4 lymphocytes decreas 1
10007839 Investigations CD4 lymphocytes decreas Definition
10008661 Investigations Cholesterol high 1
10008661 Investigations Cholesterol high Definition
10011268 Investigations CPK increased 1
10011268 Investigations CPK increased Definition
10011368 Investigations Creatinine increased 1
10011368 Investigations Creatinine increased Definition
10050528 Investigations Ejection fraction decrease2
10050528 Investigations Ejection fraction decreaseDefinition
10014383 Investigations Electrocardiogram QT corr1
10014383 Investigations Electrocardiogram QT corrDefinition
10016596 Investigations Fibrinogen decreased 1
10016596 Investigations Fibrinogen decreased Definition
10016987 Investigations Forced expiratory volume 1
10016987 Investigations Forced expiratory volume Definition
10056910 Investigations GGT increased 1
10056910 Investigations GGT increased Definition
10018748 Investigations Growth hormone abnorma1
10018748 Investigations Growth hormone abnorma2
10018748 Investigations Growth hormone abnormaDefinition
10019150 Investigations Haptoglobin decreased 1
10019150 Investigations Haptoglobin decreased Definition
10055599 Investigations Hemoglobin increased 1
10055599 Investigations Hemoglobin increased Definition
10022402 Investigations INR increased 1
10022402 Investigations INR increased Definition
10022891 Investigations Investigations - Other, spe1
10024574 Investigations Lipase increased 1
10024574 Investigations Lipase increased Definition
10025256 Investigations Lymphocyte count decrea1
10025256 Investigations Lymphocyte count decreaDefinition
10025258 Investigations Lymphocyte count increas2
10025258 Investigations Lymphocyte count increas3
10025258 Investigations Lymphocyte count increasDefinition
10029366 Investigations Neutrophil count decreas 1
10029366 Investigations Neutrophil count decreas Definition
10062646 Investigations Pancreatic enzymes decre1
10062646 Investigations Pancreatic enzymes decreDefinition
10035528 Investigations Platelet count decreased 1
10035528 Investigations Platelet count decreased Definition
10040139 Investigations Serum amylase increased 1
10040139 Investigations Serum amylase increased Definition
10059895 Investigations Urine output decreased 3
10059895 Investigations Urine output decreased 4
10059895 Investigations Urine output decreased Definition
10047580 Investigations Vital capacity abnormal 1
10047580 Investigations Vital capacity abnormal Definition
10047896 Investigations Weight gain 1
10047896 Investigations Weight gain Definition
10047900 Investigations Weight loss 1
10047900 Investigations Weight loss Definition
10049182 Investigations White blood cell decrease1
10049182 Investigations White blood cell decreaseDefinition
10000486 Metabolism and nutrition Acidosis 1
10000486 Metabolism and nutrition Acidosis Definition
10001598 Metabolism and nutrition Alcohol intolerance 2
10001598 Metabolism and nutrition Alcohol intolerance Definition
10001680 Metabolism and nutrition Alkalosis 1
10001680 Metabolism and nutrition Alkalosis Definition
10002646 Metabolism and nutrition Anorexia 1
10002646 Metabolism and nutrition Anorexia Definition
10012174 Metabolism and nutrition Dehydration 1
10012174 Metabolism and nutrition Dehydration Definition
10052426 Metabolism and nutrition Glucose intolerance 1
10052426 Metabolism and nutrition Glucose intolerance Definition
10020587 Metabolism and nutrition Hypercalcemia 1
10020587 Metabolism and nutrition Hypercalcemia Definition
10020639 Metabolism and nutrition Hyperglycemia 1
10020639 Metabolism and nutrition Hyperglycemia Definition
10020647 Metabolism and nutrition Hyperkalemia 1
10020647 Metabolism and nutrition Hyperkalemia Definition
10020670 Metabolism and nutrition Hypermagnesemia 1
10020670 Metabolism and nutrition Hypermagnesemia Definition
10020680 Metabolism and nutrition Hypernatremia 1
10020680 Metabolism and nutrition Hypernatremia Definition
10020870 Metabolism and nutrition Hypertriglyceridemia 1
10020870 Metabolism and nutrition Hypertriglyceridemia Definition
10020907 Metabolism and nutrition Hyperuricemia 1
10020907 Metabolism and nutrition Hyperuricemia Definition
10020943 Metabolism and nutrition Hypoalbuminemia 1
10020943 Metabolism and nutrition Hypoalbuminemia Definition
10020949 Metabolism and nutrition Hypocalcemia 1
10020949 Metabolism and nutrition Hypocalcemia Definition
10021005 Metabolism and nutrition Hypoglycemia 1
10021005 Metabolism and nutrition Hypoglycemia Definition
10021018 Metabolism and nutrition Hypokalemia 1
10021018 Metabolism and nutrition Hypokalemia Definition
10021028 Metabolism and nutrition Hypomagnesemia 1
10021028 Metabolism and nutrition Hypomagnesemia Definition
10021038 Metabolism and nutrition Hyponatremia 1
10021038 Metabolism and nutrition Hyponatremia Definition
10021059 Metabolism and nutrition Hypophosphatemia 1
10021059 Metabolism and nutrition Hypophosphatemia Definition
10065973 Metabolism and nutrition Iron overload 2
10065973 Metabolism and nutrition Iron overload Definition
10027433 Metabolism and nutrition Metabolism and nutrition 1d
10029883 Metabolism and nutrition Obesity 2
10029883 Metabolism and nutrition Obesity Definition
10045152 Metabolism and nutrition Tumor lysis syndrome 3
10045152 Metabolism and nutrition Tumor lysis syndrome Definition
10065775 Musculoskeletal and conneAbdominal soft tissue necr2
10065775 Musculoskeletal and conneAbdominal soft tissue necrDefinition
10003239 Musculoskeletal and conneArthralgia 1
10003239 Musculoskeletal and conneArthralgia Definition
10003246 Musculoskeletal and conneArthritis 1
10003246 Musculoskeletal and conneArthritis Definition
10066480 Musculoskeletal and conneAvascular necrosis 1
10066480 Musculoskeletal and conneAvascular necrosis Definition
10003988 Musculoskeletal and conneBack pain 1
10003988 Musculoskeletal and conneBack pain Definition
10006002 Musculoskeletal and conneBone pain 1
10006002 Musculoskeletal and conneBone pain Definition
10048677 Musculoskeletal and conneButtock pain 1
10048677 Musculoskeletal and conneButtock pain Definition
10008496 Musculoskeletal and conneChest wall pain 1
10008496 Musculoskeletal and conneChest wall pain Definition
10015688 Musculoskeletal and conneExostosis 1
10015688 Musculoskeletal and conneExostosis Definition
10065799 Musculoskeletal and conneFibrosis deep connective t1
10065799 Musculoskeletal and conneFibrosis deep connective tDefinition
10016750 Musculoskeletal and conneFlank pain 1
10016750 Musculoskeletal and conneFlank pain Definition
10062572 Musculoskeletal and conneGeneralized muscle weakn1
10062572 Musculoskeletal and conneGeneralized muscle weaknDefinition
10018761 Musculoskeletal and conneGrowth suppression 1
10018761 Musculoskeletal and conneGrowth suppression Definition
10065779 Musculoskeletal and conneHead soft tissue necrosis 2
10065779 Musculoskeletal and conneHead soft tissue necrosis Definition
10023215 Musculoskeletal and conneJoint effusion 1
10023215 Musculoskeletal and conneJoint effusion Definition
10048706 Musculoskeletal and conneJoint range of motion dec 1
10048706 Musculoskeletal and conneJoint range of motion dec Definition
10065796 Musculoskeletal and conneJoint range of motion decr1
10065796 Musculoskeletal and conneJoint range of motion decrDefinition
10065800 Musculoskeletal and conneJoint range of motion dec Definition
10023509 Musculoskeletal and conneKyphosis 1
10023509 Musculoskeletal and conneKyphosis Definition
10024842 Musculoskeletal and conneLordosis 1
10024842 Musculoskeletal and conneLordosis Definition
10065780 Musculoskeletal and conneMuscle weakness left-side1
10065780 Musculoskeletal and conneMuscle weakness left-sideDefinition
10065776 Musculoskeletal and conneMuscle weakness lower li 1
10065776 Musculoskeletal and conneMuscle weakness lower li Definition
10065794 Musculoskeletal and conneMuscle weakness right-si 1
10065794 Musculoskeletal and conneMuscle weakness right-si Definition
10065795 Musculoskeletal and conneMuscle weakness trunk 1
10065795 Musculoskeletal and conneMuscle weakness trunk Definition
10065895 Musculoskeletal and conneMuscle weakness upper l 1
10065895 Musculoskeletal and conneMuscle weakness upper l Definition
10028395 Musculoskeletal and conneMusculoskeletal and connec1
10065783 Musculoskeletal and conneMusculoskeletal deformity1
10065783 Musculoskeletal and conneMusculoskeletal deformityDefinition
10028411 Musculoskeletal and conneMyalgia 1
10028411 Musculoskeletal and conneMyalgia Definition
10028653 Musculoskeletal and conneMyositis 1
10028653 Musculoskeletal and conneMyositis Definition
10028836 Musculoskeletal and conneNeck pain 1
10028836 Musculoskeletal and conneNeck pain Definition
10065781 Musculoskeletal and conneNeck soft tissue necrosis 2
10065781 Musculoskeletal and conneNeck soft tissue necrosis Definition
10064658 Musculoskeletal and conneOsteonecrosis of jaw 1
10064658 Musculoskeletal and conneOsteonecrosis of jaw Definition
10031282 Musculoskeletal and conneOsteoporosis 1
10031282 Musculoskeletal and conneOsteoporosis Definition
10033425 Musculoskeletal and connePain in extremity 1
10033425 Musculoskeletal and connePain in extremity Definition
10065793 Musculoskeletal and connePelvic soft tissue necrosis 2
10065793 Musculoskeletal and connePelvic soft tissue necrosis Definition
10039722 Musculoskeletal and conneScoliosis 1
10039722 Musculoskeletal and conneScoliosis Definition
10065777 Musculoskeletal and conneSoft tissue necrosis lower 2
10065777 Musculoskeletal and conneSoft tissue necrosis lower Definition
10065778 Musculoskeletal and conneSoft tissue necrosis upper 2
10065778 Musculoskeletal and conneSoft tissue necrosis upper Definition
10065798 Musculoskeletal and conneSuperficial soft tissue fibro1
10065798 Musculoskeletal and conneSuperficial soft tissue fibroDefinition
10044684 Musculoskeletal and conneTrismus 1
10044684 Musculoskeletal and conneTrismus Definition
10065738 Musculoskeletal and conneUnequal limb length 1
10065738 Musculoskeletal and conneUnequal limb length Definition
10048293 Neoplasms benign, malignan
Leukemia secondary to o 4
Leukemia secondary to o 5
Leukemia secondary to o Definition
Myelodysplastic syndrome4
Myelodysplastic syndrome5
Myelodysplastic syndromeDefinition
Neoplasms benign, malignan1
Treatment related second3
Treatment related secondDefinition
Tumor pain 1
Tumor pain 2
Tumor pain 3
Tumor pain Definition
10053662 Nervous system disorders Abducens nerve disorder 1
10053662 Nervous system disorders Abducens nerve disorder Definition
10060929 Nervous system disorders Accessory nerve disorder 1
10060929 Nervous system disorders Accessory nerve disorder Definition
10000521 Nervous system disorders Acoustic nerve disorder N 1
10000521 Nervous system disorders Acoustic nerve disorder N Definition
10001540 Nervous system disorders Akathisia 1
10001540 Nervous system disorders Akathisia Definition
10001949 Nervous system disorders Amnesia 1
10001949 Nervous system disorders Amnesia Definition
10002953 Nervous system disorders Aphonia 3
10002953 Nervous system disorders Aphonia Definition
10003074 Nervous system disorders Arachnoiditis 1
10003074 Nervous system disorders Arachnoiditis Definition
10003591 Nervous system disorders Ataxia 1
10003591 Nervous system disorders Ataxia Definition
10065417 Nervous system disorders Brachial plexopathy 1
10065417 Nervous system disorders Brachial plexopathy Definition
10065784 Nervous system disorders Central nervous system ne1
10065784 Nervous system disorders Central nervous system neDefinition
10008164 Nervous system disorders Cerebrospinal fluid leakag1
10008164 Nervous system disorders Cerebrospinal fluid leakagDefinition
10009845 Nervous system disorders Cognitive disturbance 1
10009845 Nervous system disorders Cognitive disturbance Definition
10010250 Nervous system disorders Concentration impairment1
10010250 Nervous system disorders Concentration impairmentDefinition
10012373 Nervous system disorders Depressed level of consci 1
10012373 Nervous system disorders Depressed level of consci Definition
10013573 Nervous system disorders Dizziness 1
10013573 Nervous system disorders Dizziness Definition
10013887 Nervous system disorders Dysarthria 1
10013887 Nervous system disorders Dysarthria Definition
10062872 Nervous system disorders Dysesthesia 1
10062872 Nervous system disorders Dysesthesia Definition
10013911 Nervous system disorders Dysgeusia 1
10013911 Nervous system disorders Dysgeusia 2
10013911 Nervous system disorders Dysgeusia Definition
10013951 Nervous system disorders Dysphasia 1
10013951 Nervous system disorders Dysphasia Definition
10014217 Nervous system disorders Edema cerebral 4
10014217 Nervous system disorders Edema cerebral Definition
10014625 Nervous system disorders Encephalopathy 1
10014625 Nervous system disorders Encephalopathy Definition
10015832 Nervous system disorders Extrapyramidal disorder 1
10015832 Nervous system disorders Extrapyramidal disorder Definition
10051272 Nervous system disorders Facial muscle weakness 1
10051272 Nervous system disorders Facial muscle weakness Definition
10061457 Nervous system disorders Facial nerve disorder 1
10061457 Nervous system disorders Facial nerve disorder Definition
10061185 Nervous system disorders Glossopharyngeal nerve di1
10061185 Nervous system disorders Glossopharyngeal nerve diDefinition
10019211 Nervous system disorders Headache 1
10019211 Nervous system disorders Headache Definition
10020508 Nervous system disorders Hydrocephalus 1
10020508 Nervous system disorders Hydrocephalus Definition
10020765 Nervous system disorders Hypersomnia 1
10020765 Nervous system disorders Hypersomnia Definition
10061212 Nervous system disorders Hypoglossal nerve disorde1
10061212 Nervous system disorders Hypoglossal nerve disordeDefinition
10022763 Nervous system disorders Intracranial hemorrhage 1
10022763 Nervous system disorders Intracranial hemorrhage Definition
10023030 Nervous system disorders Ischemia cerebrovascular 1
10023030 Nervous system disorders Ischemia cerebrovascular 2
10023030 Nervous system disorders Ischemia cerebrovascular Definition
10065836 Nervous system disorders IVth nerve disorder 1
10065836 Nervous system disorders IVth nerve disorder Definition
10024264 Nervous system disorders Lethargy 1
10024264 Nervous system disorders Lethargy 2
10024264 Nervous system disorders Lethargy Definition
10024382 Nervous system disorders Leukoencephalopathy 1
10024382 Nervous system disorders Leukoencephalopathy Definition
10027175 Nervous system disorders Memory impairment 1
10027175 Nervous system disorders Memory impairment Definition
10027198 Nervous system disorders Meningismus 1
10027198 Nervous system disorders Meningismus Definition
10028041 Nervous system disorders Movements involuntary 1
10028041 Nervous system disorders Movements involuntary Definition
10028524 Nervous system disorders Myelitis 1
10028524 Nervous system disorders Myelitis Definition
10029205 Nervous system disorders Nervous system disorders 1-
10029223 Nervous system disorders Neuralgia 1
10029223 Nervous system disorders Neuralgia Definition
10029864 Nervous system disorders Nystagmus 2
10029864 Nervous system disorders Nystagmus 3
10029864 Nervous system disorders Nystagmus Definition
10053661 Nervous system disorders Oculomotor nerve disorde1
10053661 Nervous system disorders Oculomotor nerve disordeDefinition
10056388 Nervous system disorders Olfactory nerve disorder 2
10056388 Nervous system disorders Olfactory nerve disorder 3
10056388 Nervous system disorders Olfactory nerve disorder Definition
10033987 Nervous system disorders Paresthesia 1
10033987 Nervous system disorders Paresthesia Definition
10034580 Nervous system disorders Peripheral motor neuropa1
10034580 Nervous system disorders Peripheral motor neuropaDefinition
10034620 Nervous system disorders Peripheral sensory neurop1
10034620 Nervous system disorders Peripheral sensory neuropDefinition
10056238 Nervous system disorders Phantom pain 1
10056238 Nervous system disorders Phantom pain Definition
10036653 Nervous system disorders Presyncope 2
10036653 Nervous system disorders Presyncope Definition
10063636 Nervous system disorders Pyramidal tract syndrome 1
10063636 Nervous system disorders Pyramidal tract syndrome Definition
10061928 Nervous system disorders Radiculitis 1
10061928 Nervous system disorders Radiculitis Definition
10038130 Nervous system disorders Recurrent laryngeal nerve 1
10038130 Nervous system disorders Recurrent laryngeal nerve Definition
10063761 Nervous system disorders Reversible posterior leu 1
10063761 Nervous system disorders Reversible posterior leu Definition
10039906 Nervous system disorders Seizure 1
10039906 Nervous system disorders Seizure Definition
10040747 Nervous system disorders Sinus pain 1
10040747 Nervous system disorders Sinus pain Definition
10041349 Nervous system disorders Somnolence 1
10041349 Nervous system disorders Somnolence Definition
10041416 Nervous system disorders Spasticity 1
10041416 Nervous system disorders Spasticity Definition
10042244 Nervous system disorders Stroke 1
10042244 Nervous system disorders Stroke Definition
10042772 Nervous system disorders Syncope 3
10042772 Nervous system disorders Syncope Definition
10044391 Nervous system disorders Transient ischemic attacks1
10044391 Nervous system disorders Transient ischemic attacks2
10044391 Nervous system disorders Transient ischemic attacksDefinition
10044565 Nervous system disorders Tremor 1
10044565 Nervous system disorders Tremor Definition
10060890 Nervous system disorders Trigeminal nerve disorder 1
10060890 Nervous system disorders Trigeminal nerve disorder Definition
10061403 Nervous system disorders Vagus nerve disorder 1
10061403 Nervous system disorders Vagus nerve disorder Definition
10047166 Nervous system disorders Vasovagal reaction 3
10047166 Nervous system disorders Vasovagal reaction Definition
10016479 Pregnancy, puerperium andFetal death 5
10016479 Pregnancy, puerperium andFetal death Definition
10054746 Pregnancy, puerperium andFetal growth retardation 2
10054746 Pregnancy, puerperium and
Fetal growth retardation Definition
Pregnancy, puerperium and1
Premature delivery 1
Premature delivery Definition
Unintended pregnancy 3
Unintended pregnancy Definition
10001497 Psychiatric disorders Agitation 1
10001497 Psychiatric disorders Agitation Definition
10002652 Psychiatric disorders Anorgasmia 1
10002652 Psychiatric disorders Anorgasmia 2
10002652 Psychiatric disorders Anorgasmia Definition
10002855 Psychiatric disorders Anxiety 1
10002855 Psychiatric disorders Anxiety Definition
10010300 Psychiatric disorders Confusion 5
10010300 Psychiatric disorders Confusion Definition
10057066 Psychiatric disorders Delayed orgasm 1
10057066 Psychiatric disorders Delayed orgasm 2
10057066 Psychiatric disorders Delayed orgasm Definition
10012218 Psychiatric disorders Delirium 1
10012218 Psychiatric disorders Delirium Definition
10012260 Psychiatric disorders Delusions 2
10012260 Psychiatric disorders Delusions Definition
10012378 Psychiatric disorders Depression 1
10012378 Psychiatric disorders Depression Definition
10015533 Psychiatric disorders Euphoria 1
10015533 Psychiatric disorders Euphoria Definition
10019077 Psychiatric disorders Hallucinations 1
10019077 Psychiatric disorders Hallucinations Definition
10022437 Psychiatric disorders Insomnia 1
10022437 Psychiatric disorders Insomnia Definition
10024419 Psychiatric disorders Libido decreased 1
10024419 Psychiatric disorders Libido decreased 2
10024419 Psychiatric disorders Libido decreased Definition
10024421 Psychiatric disorders Libido increased 1
10024421 Psychiatric disorders Libido increased Definition
10026749 Psychiatric disorders Mania 1
10026749 Psychiatric disorders Mania Definition
10034719 Psychiatric disorders Personality change 1
10034719 Psychiatric disorders Personality change Definition
10037175 Psychiatric disorders Psychiatric disorders - Oth1
10037234 Psychiatric disorders Psychosis 1
10037234 Psychiatric disorders Psychosis Definition
10038743 Psychiatric disorders Restlessness 1
10038743 Psychiatric disorders Restlessness Definition
10042458 Psychiatric disorders Suicidal ideation 1
10042458 Psychiatric disorders Suicidal ideation Definition
10042464 Psychiatric disorders Suicide attempt 3
10042464 Psychiatric disorders Suicide attempt Definition
10069339 Renal and urinary disorderAcute kidney injury 1
10069339 Renal and urinary disorderAcute kidney injury Definition
10063575 Renal and urinary disorderBladder perforation 2
10063575 Renal and urinary disorderBladder perforation Definition
10048994 Renal and urinary disorderBladder spasm 1
10048994 Renal and urinary disorderBladder spasm Definition
10064848 Renal and urinary disorderChronic kidney disease 1
10064848 Renal and urinary disorderChronic kidney disease Definition
10063057 Renal and urinary disorderCystitis noninfective 1
10063057 Renal and urinary disorderCystitis noninfective Definition
10019450 Renal and urinary disorderHematuria 1
10019450 Renal and urinary disorderHematuria Definition
10019489 Renal and urinary disorderHemoglobinuria 1
10019489 Renal and urinary disorderHemoglobinuria Definition
10037032 Renal and urinary disorderProteinuria 1
10037032 Renal and urinary disorderProteinuria Definition
10038359 Renal and urinary disorderRenal and urinary disorder1
10038385 Renal and urinary disorderRenal calculi 1
10038385 Renal and urinary disorderRenal calculi Definition
10038419 Renal and urinary disorderRenal colic 1
10038419 Renal and urinary disorderRenal colic Definition
10038463 Renal and urinary disorderRenal hemorrhage 1
10038463 Renal and urinary disorderRenal hemorrhage Definition
10065368 Renal and urinary disorderUrinary fistula 2
10065368 Renal and urinary disorderUrinary fistula Definition
10046539 Renal and urinary disorderUrinary frequency 1
10046539 Renal and urinary disorderUrinary frequency 2
10046539 Renal and urinary disorderUrinary frequency Definition
10046543 Renal and urinary disorderUrinary incontinence 1
10046543 Renal and urinary disorderUrinary incontinence Definition
10046555 Renal and urinary disorderUrinary retention 1
10046555 Renal and urinary disorderUrinary retention Definition
10061574 Renal and urinary disorderUrinary tract obstruction 1
10061574 Renal and urinary disorderUrinary tract obstruction Definition
10062225 Renal and urinary disorderUrinary tract pain 1
10062225 Renal and urinary disorderUrinary tract pain Definition
10046593 Renal and urinary disorderUrinary urgency 1
10046593 Renal and urinary disorderUrinary urgency 2
10046593 Renal and urinary disorderUrinary urgency Definition
10046628 Renal and urinary disorderUrine discoloration 1
10046628 Renal and urinary disorderUrine discoloration Definition
10003883 Reproductive system and bAzoospermia 3
10003883 Reproductive system and bAzoospermia Definition
10006179 Reproductive system and bBreast atrophy 1
10006179 Reproductive system and bBreast atrophy Definition
10006298 Reproductive system and bBreast pain 1
10006298 Reproductive system and bBreast pain Definition
10013934 Reproductive system and bDysmenorrhea 1
10013934 Reproductive system and bDysmenorrhea Definition
10013941 Reproductive system and bDyspareunia 1
10013941 Reproductive system and bDyspareunia Definition
10014326 Reproductive system and bEjaculation disorder 1
10014326 Reproductive system and bEjaculation disorder 2
10014326 Reproductive system and bEjaculation disorder Definition
10061461 Reproductive system and bErectile dysfunction 1
10061461 Reproductive system and bErectile dysfunction Definition
10065789 Reproductive system and bFallopian tube obstruction1
10065789 Reproductive system and bFallopian tube obstructionDefinition
10065791 Reproductive system and bFallopian tube stenosis 1
10065791 Reproductive system and bFallopian tube stenosis Definition
10061149 Reproductive system and bFemale genital tract fistul 1
10061149 Reproductive system and bFemale genital tract fistul Definition
10054382 Reproductive system and bFeminization acquired 1
10054382 Reproductive system and bFeminization acquired 2
10054382 Reproductive system and bFeminization acquired Definition
10018146 Reproductive system and bGenital edema 1
10018146 Reproductive system and bGenital edema Definition
10018801 Reproductive system and bGynecomastia 1
10018801 Reproductive system and bGynecomastia Definition
10060602 Reproductive system and bHematosalpinx 1
10060602 Reproductive system and bHematosalpinx Definition
10022992 Reproductive system and bIrregular menstruation 1
10022992 Reproductive system and bIrregular menstruation Definition
10061261 Reproductive system and bLactation disorder 1
10061261 Reproductive system and bLactation disorder 2
10061261 Reproductive system and bLactation disorder Definition
10027313 Reproductive system and bMenorrhagia 1
10027313 Reproductive system and bMenorrhagia Definition
10065823 Reproductive system and bNipple deformity 1
10065823 Reproductive system and bNipple deformity 2
10065823 Reproductive system and bNipple deformity Definition
10030300 Reproductive system and bOligospermia 1
10030300 Reproductive system and bOligospermia Definition
10065763 Reproductive system and bOvarian hemorrhage 1
10065763 Reproductive system and bOvarian hemorrhage Definition
10033279 Reproductive system and bOvarian rupture 1
10033279 Reproductive system and bOvarian rupture Definition
10033314 Reproductive system and bOvulation pain 1
10033314 Reproductive system and bOvulation pain Definition
10064026 Reproductive system and bPelvic floor muscle weakn 4
10064026 Reproductive system and bPelvic floor muscle weakn Definition
10034263 Reproductive system and bPelvic pain 1
10034263 Reproductive system and bPelvic pain Definition
10034310 Reproductive system and bPenile pain 1
10034310 Reproductive system and bPenile pain Definition
10061339 Reproductive system and bPerineal pain 1
10061339 Reproductive system and bPerineal pain Definition
10036601 Reproductive system and bPremature menopause 3
10036601 Reproductive system and bPremature menopause Definition
10055325 Reproductive system and bProstatic hemorrhage 1
10055325 Reproductive system and bProstatic hemorrhage Definition
10055026 Reproductive system and bProstatic obstruction 1
10055026 Reproductive system and bProstatic obstruction Definition
10036968 Reproductive system and bProstatic pain 1
10036968 Reproductive system and bProstatic pain Definition
10038604 Reproductive system and bReproductive system and br
1
2
3
4
5
10039757 Reproductive system and bScrotal pain 1
10039757 Reproductive system and bScrotal pain Definition
10065762 Reproductive system and bSpermatic cord hemorrha 1
10065762 Reproductive system and bSpermatic cord hemorrha Definition
10065805 Reproductive system and bSpermatic cord obstructio1
10065805 Reproductive system and bSpermatic cord obstructioDefinition
10043306 Reproductive system and bTesticular disorder 5
10043306 Reproductive system and bTesticular disorder Definition
10055347 Reproductive system and bTesticular hemorrhage 1
10055347 Reproductive system and bTesticular hemorrhage Definition
10043345 Reproductive system and bTesticular pain 1
10043345 Reproductive system and bTesticular pain Definition
10065811 Reproductive system and bUterine fistula 1
10065811 Reproductive system and bUterine fistula Definition
10046789 Reproductive system and bUterine hemorrhage 1
10046789 Reproductive system and bUterine hemorrhage Definition
10065928 Reproductive system and bUterine obstruction 1
10065928 Reproductive system and bUterine obstruction Definition
10046809 Reproductive system and bUterine pain 1
10046809 Reproductive system and bUterine pain Definition
10046901 Reproductive system and bVaginal discharge 1
10046901 Reproductive system and bVaginal discharge 2
10046901 Reproductive system and bVaginal discharge Definition
10046904 Reproductive system and bVaginal dryness 1
10046904 Reproductive system and bVaginal dryness Definition
10065813 Reproductive system and bVaginal fistula 1
10065813 Reproductive system and bVaginal fistula Definition
10046912 Reproductive system and bVaginal hemorrhage 1
10046912 Reproductive system and bVaginal hemorrhage Definition
10046916 Reproductive system and bVaginal inflammation 5
10046916 Reproductive system and bVaginal inflammation Definition
10065817 Reproductive system and bVaginal obstruction 1
10065817 Reproductive system and bVaginal obstruction Definition
10046937 Reproductive system and bVaginal pain 1
10046937 Reproductive system and bVaginal pain Definition
10065818 Reproductive system and bVaginal perforation 1
10065818 Reproductive system and bVaginal perforation Definition
10053496 Reproductive system and bVaginal stricture 1
10053496 Reproductive system and bVaginal stricture Definition
10046947 Reproductive system and bVaginismus 1
10046947 Reproductive system and bVaginismus Definition
10001409 Respiratory, thoracic and Adult respiratory distress 3
10001409 Respiratory, thoracic and Adult respiratory distress Definition
10001723 Respiratory, thoracic and Allergic rhinitis 1
10001723 Respiratory, thoracic and Allergic rhinitis 2
10001723 Respiratory, thoracic and Allergic rhinitis Definition
10002972 Respiratory, thoracic and Apnea 3
10002972 Respiratory, thoracic and Apnea Definition
10003504 Respiratory, thoracic and Aspiration 1
10003504 Respiratory, thoracic and Aspiration Definition
10003598 Respiratory, thoracic and Atelectasis 1
10003598 Respiratory, thoracic and Atelectasis Definition
10006437 Respiratory, thoracic and Bronchial fistula 1
10006437 Respiratory, thoracic and Bronchial fistula Definition
10006440 Respiratory, thoracic and Bronchial obstruction 1
10006440 Respiratory, thoracic and Bronchial obstruction Definition
10063524 Respiratory, thoracic and Bronchial stricture 1
10063524 Respiratory, thoracic and Bronchial stricture Definition
10053481 Respiratory, thoracic and Bronchopleural fistula 1
10053481 Respiratory, thoracic and Bronchopleural fistula Definition
10065746 Respiratory, thoracic and Bronchopulmonary hemor1
10065746 Respiratory, thoracic and Bronchopulmonary hemorDefinition
10006482 Respiratory, thoracic and Bronchospasm 1
10006482 Respiratory, thoracic and Bronchospasm Definition
10051228 Respiratory, thoracic and Chylothorax 1
10051228 Respiratory, thoracic and Chylothorax Definition
10011224 Respiratory, thoracic and Cough 1
10011224 Respiratory, thoracic and Cough Definition
10013963 Respiratory, thoracic and Dyspnea 1
10013963 Respiratory, thoracic and Dyspnea Definition
10015090 Respiratory, thoracic and Epistaxis 1
10015090 Respiratory, thoracic and Epistaxis Definition
10020039 Respiratory, thoracic and Hiccups 1
10020039 Respiratory, thoracic and Hiccups Definition
10020201 Respiratory, thoracic and Hoarseness 1
10020201 Respiratory, thoracic and Hoarseness Definition
10021143 Respiratory, thoracic and Hypoxia 2
10021143 Respiratory, thoracic and Hypoxia Definition
10023838 Respiratory, thoracic and Laryngeal edema 1
10023838 Respiratory, thoracic and Laryngeal edema Definition
10065786 Respiratory, thoracic and Laryngeal fistula 1
10065786 Respiratory, thoracic and Laryngeal fistula Definition
10065759 Respiratory, thoracic and Laryngeal hemorrhage 1
10065759 Respiratory, thoracic and Laryngeal hemorrhage Definition
10065735 Respiratory, thoracic and Laryngeal inflammation 1
10065735 Respiratory, thoracic and Laryngeal inflammation Definition
10065880 Respiratory, thoracic and Laryngeal mucositis 1
10065880 Respiratory, thoracic and Laryngeal mucositis Definition
10059639 Respiratory, thoracic and Laryngeal obstruction 1
10059639 Respiratory, thoracic and Laryngeal obstruction Definition
10023862 Respiratory, thoracic and Laryngeal stenosis 1
10023862 Respiratory, thoracic and Laryngeal stenosis Definition
10062667 Respiratory, thoracic and Laryngopharyngeal dysest1
10062667 Respiratory, thoracic and Laryngopharyngeal dysestDefinition
10023891 Respiratory, thoracic and Laryngospasm 2
10023891 Respiratory, thoracic and Laryngospasm Definition
10056356 Respiratory, thoracic and Mediastinal hemorrhage 1
10056356 Respiratory, thoracic and Mediastinal hemorrhage Definition
10028735 Respiratory, thoracic and Nasal congestion 1
10028735 Respiratory, thoracic and Nasal congestion Definition
10034825 Respiratory, thoracic and Pharyngeal fistula 1
10034825 Respiratory, thoracic and Pharyngeal fistula Definition
10055315 Respiratory, thoracic and Pharyngeal hemorrhage 1
10055315 Respiratory, thoracic and Pharyngeal hemorrhage Definition
10065881 Respiratory, thoracic and Pharyngeal mucositis 1
10065881 Respiratory, thoracic and Pharyngeal mucositis Definition
10065706 Respiratory, thoracic and Pharyngeal necrosis 3
10065706 Respiratory, thoracic and Pharyngeal necrosis Definition
10050028 Respiratory, thoracic and Pharyngeal stenosis 1
10050028 Respiratory, thoracic and Pharyngeal stenosis Definition
10034844 Respiratory, thoracic and Pharyngolaryngeal pain 1
10034844 Respiratory, thoracic and Pharyngolaryngeal pain Definition
10035598 Respiratory, thoracic and Pleural effusion 1
10035598 Respiratory, thoracic and Pleural effusion Definition
10055319 Respiratory, thoracic and Pleural hemorrhage 1
10055319 Respiratory, thoracic and Pleural hemorrhage Definition
10035623 Respiratory, thoracic and Pleuritic pain 1
10035623 Respiratory, thoracic and Pleuritic pain Definition
10035742 Respiratory, thoracic and Pneumonitis 1
10035742 Respiratory, thoracic and Pneumonitis Definition
10035759 Respiratory, thoracic and Pneumothorax 1
10035759 Respiratory, thoracic and Pneumothorax Definition
10036402 Respiratory, thoracic and Postnasal drip 1
10036402 Respiratory, thoracic and Postnasal drip 2
10036402 Respiratory, thoracic and Postnasal drip Definition
10036790 Respiratory, thoracic and Productive cough 1
10036790 Respiratory, thoracic and Productive cough Definition
10037375 Respiratory, thoracic and Pulmonary edema 1
10037375 Respiratory, thoracic and Pulmonary edema Definition
10037383 Respiratory, thoracic and Pulmonary fibrosis 1
10037383 Respiratory, thoracic and Pulmonary fibrosis Definition
10065873 Respiratory, thoracic and Pulmonary fistula 1
10065873 Respiratory, thoracic and Pulmonary fistula Definition
10037400 Respiratory, thoracic and Pulmonary hypertension 1
10037400 Respiratory, thoracic and Pulmonary hypertension Definition
10038695 Respiratory, thoracic and Respiratory failure 4
10038695 Respiratory, thoracic and Respiratory failure 5
10038695 Respiratory, thoracic and Respiratory failure Definition
10038738 Respiratory, thoracic and Respiratory, thoracic and m
1
2
3
4
5
10038921 Respiratory, thoracic and Retinoic acid syndrome 1
10038921 Respiratory, thoracic and Retinoic acid syndrome Definition
10062244 Respiratory, thoracic and Sinus disorder 1
10062244 Respiratory, thoracic and Sinus disorder Definition
10040975 Respiratory, thoracic and Sleep apnea 1
10040975 Respiratory, thoracic and Sleep apnea Definition
10041232 Respiratory, thoracic and Sneezing 1
10041232 Respiratory, thoracic and Sneezing 2
10041232 Respiratory, thoracic and Sneezing Definition
10041367 Respiratory, thoracic and Sore throat 1
10041367 Respiratory, thoracic and Sore throat Definition
10042241 Respiratory, thoracic and Stridor 3
10042241 Respiratory, thoracic and Stridor Definition
10065787 Respiratory, thoracic and Tracheal fistula 1
10065787 Respiratory, thoracic and Tracheal fistula Definition
10065900 Respiratory, thoracic and Tracheal mucositis 1
10065900 Respiratory, thoracic and Tracheal mucositis Definition
10050816 Respiratory, thoracic and Tracheal stenosis 1
10050816 Respiratory, thoracic and Tracheal stenosis Definition
10047681 Respiratory, thoracic and Voice alteration 1
10047681 Respiratory, thoracic and Voice alteration Definition
10047924 Respiratory, thoracic and Wheezing 1
10047924 Respiratory, thoracic and Wheezing Definition
10001760 Skin and subcutaneous tis Alopecia 1
10001760 Skin and subcutaneous tis Alopecia 2
10001760 Skin and subcutaneous tis Alopecia Definition
10005901 Skin and subcutaneous tis Body odor 1
10005901 Skin and subcutaneous tis Body odor 2
10005901 Skin and subcutaneous tis Body odor Definition
10006556 Skin and subcutaneous tis Bullous dermatitis 1
10006556 Skin and subcutaneous tis Bullous dermatitis Definition
10013786 Skin and subcutaneous tis Dry skin 1
10013786 Skin and subcutaneous tis Dry skin Definition
10015218 Skin and subcutaneous tis Erythema multiforme 1
10015218 Skin and subcutaneous tis Erythema multiforme Definition
10015277 Skin and subcutaneous tis Erythroderma 2
10015277 Skin and subcutaneous tis Erythroderma Definition
10016241 Skin and subcutaneous tis Fat atrophy 1
10016241 Skin and subcutaneous tis Fat atrophy Definition
10020112 Skin and subcutaneous tis Hirsutism 1
10020112 Skin and subcutaneous tis Hirsutism 2
10020112 Skin and subcutaneous tis Hirsutism Definition
10020642 Skin and subcutaneous tis Hyperhidrosis 1
10020642 Skin and subcutaneous tis Hyperhidrosis Definition
10020864 Skin and subcutaneous tis Hypertrichosis 1
10020864 Skin and subcutaneous tis Hypertrichosis 2
10020864 Skin and subcutaneous tis Hypertrichosis Definition
10021013 Skin and subcutaneous tis Hypohidrosis 2
10021013 Skin and subcutaneous tis Hypohidrosis Definition
10062315 Skin and subcutaneous tis Lipohypertrophy 1
10062315 Skin and subcutaneous tis Lipohypertrophy Definition
10028691 Skin and subcutaneous tis Nail discoloration 1
10028691 Skin and subcutaneous tis Nail discoloration Definition
10049281 Skin and subcutaneous tis Nail loss 1
10049281 Skin and subcutaneous tis Nail loss 2
10049281 Skin and subcutaneous tis Nail loss Definition
10062283 Skin and subcutaneous tis Nail ridging 1
10062283 Skin and subcutaneous tis Nail ridging Definition
10033474 Skin and subcutaneous tis Pain of skin 1
10033474 Skin and subcutaneous tis Pain of skin Definition
10054524 Skin and subcutaneous tis Palmar-plantar erythrody 1
10054524 Skin and subcutaneous tis Palmar-plantar erythrody Definition
10054541 Skin and subcutaneous tis Periorbital edema 1
10054541 Skin and subcutaneous tis Periorbital edema Definition
10034966 Skin and subcutaneous tis Photosensitivity 1
10034966 Skin and subcutaneous tis Photosensitivity Definition
10037087 Skin and subcutaneous tis Pruritus 1
10037087 Skin and subcutaneous tis Pruritus Definition
10037549 Skin and subcutaneous tis Purpura 1
10037549 Skin and subcutaneous tis Purpura Definition
10037847 Skin and subcutaneous tis Rash acneiform 1
10037847 Skin and subcutaneous tis Rash acneiform Definition
10037868 Skin and subcutaneous tis Rash maculo-papular 1
10037868 Skin and subcutaneous tis Rash maculo-papular Definition
10049120 Skin and subcutaneous tis Scalp pain 1
10049120 Skin and subcutaneous tis Scalp pain Definition
10040785 Skin and subcutaneous tis Skin and subcutaneous tiss1
10040799 Skin and subcutaneous tis Skin atrophy 1
10040799 Skin and subcutaneous tis Skin atrophy Definition
10040865 Skin and subcutaneous tis Skin hyperpigmentation 1
10040865 Skin and subcutaneous tis Skin hyperpigmentation 2
10040865 Skin and subcutaneous tis Skin hyperpigmentation Definition
10040868 Skin and subcutaneous tis Skin hypopigmentation 1
10040868 Skin and subcutaneous tis Skin hypopigmentation 2
10040868 Skin and subcutaneous tis Skin hypopigmentation Definition
10051837 Skin and subcutaneous tis Skin induration 1
10051837 Skin and subcutaneous tis Skin induration Definition
10040947 Skin and subcutaneous tis Skin ulceration 1
10040947 Skin and subcutaneous tis Skin ulceration Definition
10042033 Skin and subcutaneous tis Stevens-Johnson syndrom3
10042033 Skin and subcutaneous tis Stevens-Johnson syndromDefinition
10043189 Skin and subcutaneous tis Telangiectasia 1
10043189 Skin and subcutaneous tis Telangiectasia 2
10043189 Skin and subcutaneous tis Telangiectasia Definition
10044223 Skin and subcutaneous tis Toxic epidermal necrolysis4
10044223 Skin and subcutaneous tis Toxic epidermal necrolysis5
10044223 Skin and subcutaneous tis Toxic epidermal necrolysisDefinition
10046735 Skin and subcutaneous tis Urticaria 1
10046735 Skin and subcutaneous tis Urticaria Definition
10027308 Social circumstances Menopause 1
10027308 Social circumstances Menopause Definition
10041244 Social circumstances Social circumstances - Oth1
10042613 Surgical and medical proc Surgical and medical proce1
10007196 Vascular disorders Capillary leak syndrome 2
10007196 Vascular disorders Capillary leak syndrome Definition
10016825 Vascular disorders Flushing 1
10016825 Vascular disorders Flushing Definition
10019428 Vascular disorders Hematoma 1
10019428 Vascular disorders Hematoma Definition
10020407 Vascular disorders Hot flashes 1
10020407 Vascular disorders Hot flashes Definition
10020772 Vascular disorders Hypertension 1
10020772 Vascular disorders Hypertension Definition
10021097 Vascular disorders Hypotension 1
10021097 Vascular disorders Hypotension Definition
10065773 Vascular disorders Lymph leakage 2
10065773 Vascular disorders Lymph leakage Definition
10025233 Vascular disorders Lymphedema 1
10025233 Vascular disorders Lymphedema Definition
10048642 Vascular disorders Lymphocele 1
10048642 Vascular disorders Lymphocele Definition
10034578 Vascular disorders Peripheral ischemia 2
10034578 Vascular disorders Peripheral ischemia Definition
10034879 Vascular disorders Phlebitis 2
10034879 Vascular disorders Phlebitis Definition
10042554 Vascular disorders Superficial thrombophlebit2
10042554 Vascular disorders Superficial thrombophlebitDefinition
10042569 Vascular disorders Superior vena cava syndr 1
10042569 Vascular disorders Superior vena cava syndr Definition
10043565 Vascular disorders Thromboembolic event 1
10043565 Vascular disorders Thromboembolic event Definition
10047065 Vascular disorders Vascular disorders - Other,1
10047115 Vascular disorders Vasculitis 1
10047115 Vascular disorders Vasculitis Definition
10054692 Vascular disorders Visceral arterial ischemia 2
10054692 Vascular disorders Visceral arterial ischemia Definition
v4.03 CTCAE Grade Descri Change Type v5.0 MedDRA Code v5.0 MedDRA SOC
Hemoglobin (Hgb) <LLN - 1 N/A 10002272 Blood and lymphatic syste
Hgb <10.0 - 8.0 g/dL; <6.2 N/A 10002272 Blood and lymphatic syste
Hgb <8.0 g/dL; <4.9 mmol/L N/A 10002272 Blood and lymphatic syste
Life-threatening consequen N/A 10002272 Blood and lymphatic syste
Death N/A 10002272 Blood and lymphatic syste
A disorder characterized b Clarification 10002272 Blood and lymphatic syste
Asymptomatic or mild sympt N/A 10005329 Blood and lymphatic syste
Moderate; minimal, local o N/A 10005329 Blood and lymphatic syste
Severe or medically signifi Clarification 10005329 Blood and lymphatic syste
Mildly hypocellular or <=2 N/A 10048580 Blood and lymphatic syste
Moderately hypocellular or N/A 10048580 Blood and lymphatic syste
Severely hypocellular or > N/A 10048580 Blood and lymphatic syste
Aplastic persistent for lo N/A 10048580 Blood and lymphatic syste
A disorder characterized N/A 10048580 Blood and lymphatic syste
Laboratory findings with n N/A 10013442 Blood and lymphatic syste
Laboratory findings and b N/A 10013442 Blood and lymphatic syste
A disorder characterized b N/A 10013442 Blood and lymphatic syste
ANC <1000/mm3 with a sing N/A 10016288 Blood and lymphatic syste
Laboratory evidence of hem N/A 10019491 Blood and lymphatic syste
Evidence of hemolysis an Clarification 10019491 Blood and lymphatic syste
Transfusion or medical inte N/A 10019491 Blood and lymphatic syste
Laboratory findings with cl N/A 10019515 Blood and lymphatic syste
Life-threatening conseque N/A 10019515 Blood and lymphatic syste
Evidence of RBC destructio Deletion 10019491 Blood and lymphatic syste
>100,000/mm3 N/A 10024378 Blood and lymphatic syste
Clinical manifestations of N/A 10024378 Blood and lymphatic syste
Mild pain N/A 10025182 Blood and lymphatic syste
Moderate pain; limiting i N/A 10025182 Blood and lymphatic syste
Severe pain; limiting self N/A 10025182 Blood and lymphatic syste
Incidental findings (e.g., Deletion 10005329 Blood and lymphatic syste
Prophylactic antibiotics in Deletion 10005329 Blood and lymphatic syste
Life-threatening consequen Deletion 10005329 Blood and lymphatic syste
Death Deletion 10005329 Blood and lymphatic syste
A disorder of the spleen. Deletion 10005329 Blood and lymphatic syste
Evidence of RBC destructio Deletion 10019491 Blood and lymphatic syste
Laboratory findings with cl N/A 10043648 Blood and lymphatic syste
Life-threatening conseque N/A 10043648 Blood and lymphatic syste
Symptomatic, progressive Deletion 10008481 Cardiac disorders
Symptomatic, unstable ang Deletion 10008481 Cardiac disorders
Symptomatic, unstable ang Deletion 10028596 Cardiac disorders
Death Deletion 10028596 Cardiac disorders
A disorder characterized b Deletion 10008481 Cardiac disorders
Asymptomatic valvular thic N/A 10061589 Cardiac disorders
Asymptomatic; moderate re N/A 10061589 Cardiac disorders
Symptomatic; severe regur N/A 10061589 Cardiac disorders
Life-threatening consequen N/A 10061589 Cardiac disorders
Death N/A 10061589 Cardiac disorders
A disorder characterized by N/A 10061589 Cardiac disorders
Periods of asystole; non- N/A 10003586 Cardiac disorders
Asymptomatic, interventio N/A 10003658 Cardiac disorders
Non-urgent medical interv N/A 10003658 Cardiac disorders
Symptomatic and incomplete Clarification 10003658 Cardiac disorders
Life-threatening consequen Clarification 10003658 Cardiac disorders
A disorder characterized b N/A 10003658 Cardiac disorders
Non-urgent intervention i N/A 10003673 Cardiac disorders
Non-urgent intervention i N/A 10003674 Cardiac disorders
Asymptomatic or mild sympt N/A 10007541 Cardiac disorders
Moderate; minimal, local o N/A 10007541 Cardiac disorders
Severe or medically signifi Clarification 10007541 Cardiac disorders
Mild pain N/A 10008481 Cardiac disorders
Moderate pain; limiting i Clarification 10008481 Cardiac disorders
Pain at rest; limiting self Clarification 10008481 Cardiac disorders
A disorder characterized b Clarification 10008481 Cardiac disorders
Mild symptoms; interventi N/A 10010276 Cardiac disorders
Moderate symptoms Clarification 10010276 Cardiac disorders
Severe symptoms; interven Clarification 10010276 Cardiac disorders
Symptomatic heart failure Deletion 10034484 Cardiac disorders
Refractory heart failure o Deletion 10034484 Cardiac disorders
Asymptomatic with laborato N/A 10019279 Cardiac disorders
Symptoms with mild to mod Clarification 10019279 Cardiac disorders
Severe with symptoms at re Clarification 10019279 Cardiac disorders
Life-threatening conseque N/A 10019279 Cardiac disorders
Symptomatic due to drop in N/A 10069501 Cardiac disorders
Refractory or poorly contro N/A 10069501 Cardiac disorders
A disorder characterized b Clarification 10069501 Cardiac disorders
Symptomatic; medical inte N/A 10027786 Cardiac disorders
Symptomatic; medical inte N/A 10027787 Cardiac disorders
Symptomatic and incomplete N/A 10027787 Cardiac disorders
Asymptomatic and cardiac N/A 10028596 Cardiac disorders
Severe symptoms; cardiac N/A 10028596 Cardiac disorders
Life-threatening consequ N/A 10028596 Cardiac disorders
Severe with symptoms at re Clarification 10028606 Cardiac disorders
Life-threatening conseque N/A 10028606 Cardiac disorders
Asymptomatic with laborato Deletion 10007541 Cardiac disorders
Mild symptoms; interventi N/A 10033557 Cardiac disorders
Intervention indicated N/A 10033557 Cardiac disorders
Symptomatic; medical ma Clarification 10034040 Cardiac disorders
IV medication indicated Clarification 10034040 Cardiac disorders
Asymptomatic effusion siz N/A 10034474 Cardiac disorders
Effusion with physiologic N/A 10034474 Cardiac disorders
Asymptomatic, ECG or physic N/A 10034484 Cardiac disorders
Symptomatic pericarditis (e N/A 10034484 Cardiac disorders
Pericarditis with physiolog N/A 10034484 Cardiac disorders
Symptomatic heart failure Clarification 10038748 Cardiac disorders
Refractory heart failure o N/A 10038748 Cardiac disorders
Asymptomatic with laborato N/A 10058597 Cardiac disorders
Severe symptoms, associat Clarification 10058597 Cardiac disorders
Life-threatening consequenc N/A 10058597 Cardiac disorders
Non-urgent intervention i Clarification 10040639 Cardiac disorders
Severe, medically significa Clarification 10040639 Cardiac disorders
Symptomatic, medical inte Clarification 10040741 Cardiac disorders
Severe, medically significa Clarification 10040741 Cardiac disorders
Symptomatic; non-urgent m N/A 10040752 Cardiac disorders
Urgent medical interventi N/A 10040752 Cardiac disorders
Medical intervention indi Clarification 10042604 Cardiac disorders
Life-threatening consequ Clarification 10047281 Cardiac disorders
Asymptomatic, interventio Deletion 10007541 Cardiac disorders
Non-urgent medical interv Deletion 10007541 Cardiac disorders
Symptomatic and incomplet Deletion 10007541 Cardiac disorders
Life-threatening consequen Deletion 10007541 Cardiac disorders
Asymptomatic or mild sympt N/A 10010331 Congenital, familial and ge
Moderate; minimal, local o N/A 10010331 Congenital, familial and ge
Severe or medically signifi Clarification 10010331 Congenital, familial and ge
Life-threatening consequen N/A 10010331 Congenital, familial and ge
Death N/A 10010331 Congenital, familial and ge
Asymptomatic or mild sympt N/A 10013993 Ear and labyrinth disorder
Moderate; minimal, local o N/A 10013993 Ear and labyrinth disorder
Severe or medically signifi Clarification 10013993 Ear and labyrinth disorder
Life-threatening consequen N/A 10013993 Ear and labyrinth disorder
Death N/A 10013993 Ear and labyrinth disorder
Mild pain N/A 10014020 Ear and labyrinth disorder
Moderate pain; limiting i N/A 10014020 Ear and labyrinth disorder
Severe pain; limiting self N/A 10014020 Ear and labyrinth disorder
A disorder characterized b N/A 10014020 Ear and labyrinth disorder
External otitis with eryt Deletion 10033072 Infections and infestations
External otitis with moi Deletion 10033072 Infections and infestations
External otitis with mastoi Deletion 10033072 Infections and infestations
Urgent operative intervent Deletion 10033072 Infections and infestations
Death Deletion 10033072 Infections and infestations
A disorder characterized b Deletion 10033072 Infections and infestations
Mild pain N/A 10065785 Ear and labyrinth disorder
Moderate pain; limiting i N/A 10065785 Ear and labyrinth disorder
Severe pain; limiting self N/A 10065785 Ear and labyrinth disorder
A
Pediatric (on a 1, 2, 4, 3, 6 and 8 kHz audiogram): Threshold shift >20 dBEar
disorder characterized b N/A 10065785 at 8and
kHzlabyrinth disorder
in at least one ear.
Clarification 10019245 Ear and labyrinth disorder
Pediatric (on a 1, 2, 3, 4, 6 and 8 kHz audiogram): Threshold shift >20 dB at 4 kHz and above in at least one ear.
Clarification
Pediatric (on a 1, 2, 3, 4, 6 and 8kHz audiogram):10019245 Ear and labyrinth
hearing loss sufficient to indicate therapeuticdisorder
intervention, including hearing
Pediatric: Audiologic indication for cochlear implant and additional speech-language related services indicated.
Serous otitis N/A 10065838 Ear and labyrinth disorder
Serous otitis, medical inte N/A 10065838 Ear and labyrinth disorder
Mastoiditis; necrosis of ca N/A 10065838 Ear and labyrinth disorder
Life-threatening consequen N/A 10065838 Ear and labyrinth disorder
Death N/A 10065838 Ear and labyrinth disorder
Mild symptoms; interventi N/A 10043882 Ear and labyrinth disorder
Moderate symptoms; limit N/A 10043882 Ear and labyrinth disorder
Severe symptoms; limiting N/A 10043882 Ear and labyrinth disorder
A disorder characterized by N/A 10043882 Ear and labyrinth disorder
Mild symptoms N/A 10047340 Ear and labyrinth disorder
Moderate symptoms; limit N/A 10047340 Ear and labyrinth disorder
A disorder characterized by N/A 10047340 Ear and labyrinth disorder
Symptomatic; limiting ins N/A 10047386 Ear and labyrinth disorder
Asymptomatic; clinical or N/A 10001367 Endocrine disorders
Moderate symptoms; medic N/A 10001367 Endocrine disorders
Severe symptoms; hospital N/A 10001367 Endocrine disorders
Life-threatening consequen N/A 10001367 Endocrine disorders
Death N/A 10001367 Endocrine disorders
A disorder that occurs whe Clarification 10001367 Endocrine disorders
Mild symptoms; interventi N/A 10011655 Endocrine disorders
Severe symptoms, medical i N/A 10011655 Endocrine disorders
A disorder characterized b N/A 10011655 Endocrine disorders
No breast development by N/A 10012205 Endocrine disorders
No breast development by N/A 10012205 Endocrine disorders
Asymptomatic or mild sympt N/A 10014698 Endocrine disorders
Moderate; minimal, local o N/A 10014698 Endocrine disorders
Severe or medically signifi Clarification 10014698 Endocrine disorders
>= +2 SD (standard deviati N/A 10018746 Endocrine disorders
Symptomatic; thyroid supp N/A 10020850 Endocrine disorders
Severe symptoms; limiting N/A 10020850 Endocrine disorders
A disorder characterized N/A 10020850 Endocrine disorders
Severe symptoms; medical i N/A 10021041 Endocrine disorders
Symptomatic; thyroid repl N/A 10021114 Endocrine disorders
Severe symptoms; limiting N/A 10021114 Endocrine disorders
Physical signs of puberty N/A 10058084 Endocrine disorders
Physical signs and biochem N/A 10058084 Endocrine disorders
Intervention not indicated N/A 10005886 Eye disorders
Symptomatic; limiting ins Clarification 10005886 Eye disorders
Limiting self care ADL Clarification 10005886 Eye disorders
A disorder characterized b N/A 10005886 Eye disorders
Asymptomatic; clinical or N/A 10007739 Eye disorders
Symptomatic; moderate decr Clarification 10007739 Eye disorders
Symptomatic with marked de Clarification 10007739 Eye disorders
Blindness (20/200 or worse Clarification 10007739 Eye disorders
A disorder characterized by N/A 10007739 Eye disorders
Asymptomatic or mild symp Primary SOC change 10010741 Infections and infestations
Symptomatic; topicalClarification,
interv Primary SOC change
10010741 Infections and infestations
Limiting self care ADL
Clarification, Primary SOC change
10010741 Infections and infestations
A disorder characterized b Primary SOC change 10010741 Infections and infestations
Symptomatic; medical inter Deletion 10048492 Eye disorders
Limiting self care ADL; de Clarification 10048492 Eye disorders
Perforation or blindness ( Clarification 10048492 Eye disorders
Asymptomatic; clinical or Clarification 10013774 Eye disorders
Symptomatic; multiple agen Clarification 10013774 Eye disorders
Decrease in visual acuity ( Clarification 10013774 Eye disorders
Limiting self care ADL; dis Clarification 10015829 Eye disorders
Asymptomatic or mild sympt Clarification 10015919 Eye disorders
Moderate; minimal, local o Clarification 10015919 Eye disorders
Severe or medically signifi Clarification 10015919 Eye disorders
Sight-threatening conseque Clarification 10015919 Eye disorders
Mild pain N/A 10015958 Eye disorders
Moderate pain; limiting i N/A 10015958 Eye disorders
Severe pain; limiting self N/A 10015958 Eye disorders
Symptomatic; nonoperative N/A 10061145 Eye disorders
Limiting self care ADL; ope N/A 10061145 Eye disorders
Symptomatic but not limit N/A 10016757 Eye disorders
Limiting instrumental ADL N/A 10016757 Eye disorders
Limiting self care ADL N/A 10016757 Eye disorders
Elevated intraocular pressu Clarification 10018304 Eye disorders
EIOP causing early visual f Clarification 10018304 Eye disorders
EIOP causing marked visual Clarification 10018304 Eye disorders
Symptomatic; medical inter Clarification 10023332 Eye disorders
Decline in vision (worse th Clarification 10023332 Eye disorders
Perforation or blindness ( Clarification 10023332 Eye disorders
Limiting instrumental ADL Clarification 10029404 Eye disorders
Limiting self care ADL Clarification 10029404 Eye disorders
Limiting vision of the affe Clarification 10061322 Eye disorders
Limiting vision in the aff Clarification 10061322 Eye disorders
Asymptomatic; no visual fi Clarification 10033703 Eye disorders
Symptomatic decline in visi Clarification 10033703 Eye disorders
Marked visual field defect Clarification 10033703 Eye disorders
Asymptomatic Deletion 10038848 Eye disorders
Exudative and visual acuit Deletion 10038848 Eye disorders
Rhegmatogenous or exudati Clarification 10038848 Eye disorders
Vitroretinal surgical repair Deletion 10038848 Eye disorders
Blindness (20/200 or worse Deletion 10038848 Eye disorders
Laser therapy or pneumop Clarification 10038897 Eye disorders
Topical medication indica Clarification 10038901 Eye disorders
Intravitreal medication; o Clarification 10038901 Eye disorders
Symptomatic with moderate Clarification 10038923 Eye disorders
Symptomatic with marked de Clarification 10038923 Eye disorders
A disorder involving the re N/A 10038923 Eye disorders
Symptomatic, limiting inst Clarification 10061510 Eye disorders
Symptomatic, limiting self Clarification 10061510 Eye disorders
Anterior uveitis; medical i Clarification 10046851 Eye disorders
Posterior or pan-uveitis Clarification 10046851 Eye disorders
Asymptomatic or mild sympt Clarification 10047656 Eye disorders
Limiting self care ADL; vit Clarification 10047656 Eye disorders
A disorder characterized b Clarification 10047656 Eye disorders
Intervention not indicated N/A 10047848 Eye disorders
Intervention indicated Clarification 10047848 Eye disorders
Operative intervention ind Clarification 10047848 Eye disorders
A disorder of excessive tea Clarification 10047848 Eye disorders
Asymptomatic; clinical or N/A 10000060 Gastrointestinal disorders
Symptomatic; limiting ins N/A 10000060 Gastrointestinal disorders
Severe discomfort; limiting N/A 10000060 Gastrointestinal disorders
A disorder characterized N/A 10000060 Gastrointestinal disorders
Mild pain N/A 10000081 Gastrointestinal disorders
Moderate pain; limiting i N/A 10000081 Gastrointestinal disorders
Severe pain; limiting self N/A 10000081 Gastrointestinal disorders
A disorder characterized b N/A 10000081 Gastrointestinal disorders
Asymptomatic; clinical or Clarification 10002156 Gastrointestinal disorders
Symptomatic; altered GI f Clarification 10002156 Gastrointestinal disorders
Severely altered GI functio Clarification 10002156 Gastrointestinal disorders
Life-threatening consequen N/A 10002156 Gastrointestinal disorders
Death N/A 10002156 Gastrointestinal disorders
Mild; intervention not ind Clarification 10055226 Gastrointestinal disorders
Moderate symptoms; medica Clarification 10055226 Gastrointestinal disorders
Transfusion, radiologic, en Clarification 10055226 Gastrointestinal disorders
Life-threatening consequen Deletion 10002180 Gastrointestinal disorders
Death Deletion 10002180 Gastrointestinal disorders
Asymptomatic or mild symp N/A 10065721 Gastrointestinal disorders
Symptomatic; medical inter N/A 10065721 Gastrointestinal disorders
Severe symptoms; limiting N/A 10065721 Gastrointestinal disorders
A disorder characterized Clarification 10065721 Gastrointestinal disorders
TPN or hospitalization indi Clarification 10065722 Gastrointestinal disorders
A disorder characterized by N/A 10065722 Gastrointestinal disorders
Symptomatic; altered GI f N/A 10002176 Gastrointestinal disorders
Symptomatic and severely a N/A 10002176 Gastrointestinal disorders
Severely altered GI functi Clarification 10002180 Gastrointestinal disorders
A disorder characterized b Clarification 10002180 Gastrointestinal disorders
Symptomatic; medical inte N/A 10003445 Gastrointestinal disorders
Severe symptoms; invasive N/A 10003445 Gastrointestinal disorders
No change in bowel functio N/A 10005265 Gastrointestinal disorders
Symptomatic, decreased or N/A 10005265 Gastrointestinal disorders
Moderate symptoms; limit N/A 10008417 Gastrointestinal disorders
Abdominal pain; mucus or N/A 10009887 Gastrointestinal disorders
Severe abdominal pain; cha Clarification 10009887 Gastrointestinal disorders
Hospitalization indicated; Clarification 10010000 Gastrointestinal disorders
Symptomatic; medical inte Clarification 10010001 Gastrointestinal disorders
Severe symptoms; elective Clarification 10010001 Gastrointestinal disorders
Severely altered GI functio N/A 10010004 Gastrointestinal disorders
Occasional or intermittent N/A 10010774 Gastrointestinal disorders
Persistent symptoms with r N/A 10010774 Gastrointestinal disorders
Obstipation with manual ev N/A 10010774 Gastrointestinal disorders
One or more dental caries, N/A 10012318 Gastrointestinal disorders
Dental caries involving the N/A 10012318 Gastrointestinal disorders
Dental caries resulting in p N/A 10012318 Gastrointestinal disorders
Increase of <4 stools per N/A 10012727 Gastrointestinal disorders
Increase of 4 - 6 stools p Clarification 10012727 Gastrointestinal disorders
Increase of >=7 stools per Clarification 10012727 Gastrointestinal disorders
Symptomatic (e.g., dry or t N/A 10013781 Gastrointestinal disorders
Moderate symptoms; oral in N/A 10013781 Gastrointestinal disorders
Inability to adequately al N/A 10013781 Gastrointestinal disorders
Hospitalization or elective Clarification 10013830 Gastrointestinal disorders
Mild symptoms; interventi N/A 10013946 Gastrointestinal disorders
Moderate symptoms; medic N/A 10013946 Gastrointestinal disorders
Severe symptoms; surgical Clarification 10013946 Gastrointestinal disorders
Symptomatic, able to eat r N/A 10013950 Gastrointestinal disorders
Symptomatic and altered N/A 10013950 Gastrointestinal disorders
Severely altered eating/sw Clarification 10013950 Gastrointestinal disorders
Abdominal pain; mucus or N/A 10014893 Gastrointestinal disorders
Severe or persistent abdomi N/A 10014893 Gastrointestinal disorders
Symptomatic; noninvasive Clarification 10062570 Gastrointestinal disorders
Severe, medically significa Clarification 10062570 Gastrointestinal disorders
Inability to aliment adequa Clarification 10065727 Gastrointestinal disorders
Symptomatic; altered GI fu N/A 10015387 Gastrointestinal disorders
Self-limited; intervention N/A 10015453 Gastrointestinal disorders
Symptomatic; altered eati Clarification 10015461 Gastrointestinal disorders
Severely altered eating/sw Clarification 10015461 Gastrointestinal disorders
Occasional use of pads re N/A 10016296 Gastrointestinal disorders
Daily use of pads required N/A 10016296 Gastrointestinal disorders
Severe symptoms; elective N/A 10016296 Gastrointestinal disorders
Moderate; persistent; psy N/A 10016766 Gastrointestinal disorders
A disorder characterized by Clarification 10016766 Gastrointestinal disorders
Life-threatening consequen Clarification 10065713 Gastrointestinal disorders
Inability to aliment adequa Clarification 10051886 Gastrointestinal disorders
Severely altered eating or N/A 10017853 Gastrointestinal disorders
Moderate symptoms; medic N/A 10066874 Gastrointestinal disorders
Severe symptoms; surgical Clarification 10066874 Gastrointestinal disorders
Asymptomatic or mild sympt N/A 10017947 Gastrointestinal disorders
Moderate; minimal, local o N/A 10017947 Gastrointestinal disorders
Severe or medically signifi Clarification 10017947 Gastrointestinal disorders
Mild nausea, early satiety N/A 10018043 Gastrointestinal disorders
Moderate symptoms; able t N/A 10018043 Gastrointestinal disorders
Weight loss; refractory to Clarification 10018043 Gastrointestinal disorders
Moderate pain interfering N/A 10018286 Gastrointestinal disorders
Severe pain; inability to al N/A 10018286 Gastrointestinal disorders
Symptomatic; banding or m N/A 10019611 Gastrointestinal disorders
Severe symptoms; radiologi Clarification 10019611 Gastrointestinal disorders
Symptomatic; altered GI fu Clarification 10065730 Gastrointestinal disorders
Medical intervention or mi Clarification 10055291 Gastrointestinal disorders
Altered diet; oral interven N/A 10025476 Gastrointestinal disorders
Inability to aliment adequ N/A 10025476 Gastrointestinal disorders
Moderate pain; not interfe Clarification 10028130 Gastrointestinal disorders
Severe pain; interfering wi N/A 10028130 Gastrointestinal disorders
Loss of appetite without al N/A 10028813 Gastrointestinal disorders
Oral intake decreased with N/A 10028813 Gastrointestinal disorders
Inadequate oral caloric or N/A 10028813 Gastrointestinal disorders
Mild discomfort; not interf N/A 10054520 Gastrointestinal disorders
Moderate pain; interfering N/A 10054520 Gastrointestinal disorders
Disabling pain; tube feedi N/A 10054520 Gastrointestinal disorders
Tube feeding or TPN indica Clarification 10058096 Gastrointestinal disorders
Enzyme elevation or radiol Clarification 10033645 Gastrointestinal disorders
Severe pain; vomiting; medi N/A 10033645 Gastrointestinal disorders
Gingival recession or gingi N/A 10034536 Gastrointestinal disorders
Moderate gingival recessio N/A 10034536 Gastrointestinal disorders
Spontaneous bleeding; seve N/A 10034536 Gastrointestinal disorders
A disorder in the gingival N/A 10034536 Gastrointestinal disorders
Tube feeding or TPN indic Clarification 10065704 Gastrointestinal disorders
Rectal discomfort, interve N/A 10036774 Gastrointestinal disorders
Symptoms (e.g., rectal dis Clarification 10036774 Gastrointestinal disorders
Severe symptoms; fecal urg N/A 10036774 Gastrointestinal disorders
Tube feeding or TPN indica Clarification 10065709 Gastrointestinal disorders
Symptomatic; altered GI fun N/A 10038080 Gastrointestinal disorders
Self-limited; intervention N/A 10038981 Gastrointestinal disorders
Transfusion, medical, radio Clarification 10038981 Gastrointestinal disorders
Slightly thickened saliva; sl N/A 10056681 Gastrointestinal disorders
Thick, ropy, sticky saliva; N/A 10056681 Gastrointestinal disorders
Acute salivary gland necros Clarification 10056681 Gastrointestinal disorders
Symptomatic; altered GI fu Clarification 10039411 Gastrointestinal disorders
Severe pain; interfering wi N/A 10065710 Gastrointestinal disorders
Symptomatic and severely a N/A 10062263 Gastrointestinal disorders
Asymptomatic; hypoplasia N/A 10044030 Gastrointestinal disorders
Impairment correctable wi N/A 10044030 Gastrointestinal disorders
Maldevelopment with impai Clarification 10044030 Gastrointestinal disorders
Surface stains N/A 10044031 Gastrointestinal disorders
Symptomatic (e.g., abdomin N/A 10045271 Gastrointestinal disorders
1 - 2 episodes (separated Clarification 10047700 Gastrointestinal disorders
3 - 5 episodes (separated Clarification 10047700 Gastrointestinal disorders
>=6 episodes (separated by Clarification 10047700 Gastrointestinal disorders
Mild sensation of cold; shi N/A 10008531 General disorders and admi
Moderate tremor of the ent N/A 10008531 General disorders and admi
Severe or prolonged, not r N/A 10008531 General disorders and admi
A disorder characterized b N/A 10008531 General disorders and admi
Death Deletion 10011912 General disorders and admi
A disorder characterized by Clarification 10011912 General disorders and admi
Death N/A 10011914 General disorders and admi
A cessation of life that c Clarification 10011914 General disorders and admi
Localized facial edema N/A 10014222 General disorders and admi
Moderate localized facial N/A 10014222 General disorders and admi
Severe swelling; limiting s N/A 10014222 General disorders and admi
A disorder characterized by N/A 10014222 General disorders and admi
5 - 10% inter-limb discrep N/A 10050068 General disorders and admi
>10 - 30% inter-limb discr N/A 10050068 General disorders and admi
>30% inter-limb discrepanc N/A 10050068 General disorders and admi
Swelling or obscuration of N/A 10058720 General disorders and admi
Readily apparent obscurati N/A 10058720 General disorders and admi
Gross deviation from norma N/A 10058720 General disorders and admi
Mild pain N/A 10016059 General disorders and admi
Moderate pain; limiting i N/A 10016059 General disorders and admi
Severe pain; limiting self N/A 10016059 General disorders and admi
Fatigue relieved by rest N/A 10016256 General disorders and admi
Fatigue not relieved by res N/A 10016256 General disorders and admi
Fatigue not relieved by res N/A 10016256 General disorders and admi
38.0 - 39.0 degrees C (100 N/A 10016558 General disorders and admi
>39.0 - 40.0 degrees C (10 N/A 10016558 General disorders and admi
>40.0 degrees C (>104.0 de N/A 10016558 General disorders and admi
>40.0 degrees C (>104.0 de N/A 10016558 General disorders and admi
Mild flu-like symptoms pr N/A 10016791 General disorders and admi
Moderate symptoms; limit N/A 10016791 General disorders and admi
Severe symptoms; limiting N/A 10016791 General disorders and admi
Mild change in gait (e.g., N/A 10017577 General disorders and admi
Moderate change in gait (e N/A 10017577 General disorders and admi
Disabling; limiting self car Clarification 10017577 General disorders and admi
Asymptomatic or mild sympt N/A 10018065 General disorders and admi
Moderate; minimal, local o N/A 10018065 General disorders and admi
Severe or medically signifi Clarification 10018065 General disorders and admi
Life-threatening consequen N/A 10018065 General disorders and admi
35 - >32 degrees C; 95 - N/A 10021113 General disorders and admi
32 - >28 degrees C; 89.6 - N/A 10021113 General disorders and admi
<=28 degrees C; 82.4 degre N/A 10021113 General disorders and admi
A disorder characterized N/A 10021113 General disorders and admi
Mild transient reaction; in Primary SOC change 10051792 Injury, poisoning and proc
Therapy or infusion interr Primary SOC change 10051792 Injury, poisoning and proc
Prolonged (e.g., not rapid Primary SOC change 10051792 Injury, poisoning and proc
Life-threatening consequenPrimary SOC change 10051792 Injury, poisoning and proc
Death Primary SOC change 10051792 Injury, poisoning and proc
A disorder characterized b Primary SOC change 10051792 Injury, poisoning and proc
Erythema with associated s N/A 10064774 General disorders and admi
Ulceration or necrosis; se N/A 10064774 General disorders and admi
A disorder characterized b Clarification 10064774 General disorders and admi
Tenderness with or withou N/A 10022095 General disorders and admi
Pain; lipodystrophy; edema N/A 10022095 General disorders and admi
Ulceration or necrosis; se N/A 10022095 General disorders and admi
Mild; easily consolable Primary SOC change 10022998 Psychiatric disorders
Moderate; limiting instrumPrimary SOC change 10022998 Psychiatric disorders
Severe abnormal or Clarification,
excessi Primary SOC change
10022998 Psychiatric disorders
A disorder characterized b Primary SOC change 10022998 Psychiatric disorders
Localized to dependent are N/A 10062466 General disorders and admi
Moderate localized edema N/A 10062466 General disorders and admi
Severe localized edema and N/A 10062466 General disorders and admi
Uneasiness or lack of well N/A 10025482 General disorders and admi
Uneasiness or lack of well Clarification 10025482 General disorders and admi
Shock with azotemia and ac N/A 10028154 General disorders and admi
Life-threatening consequenc N/A 10028154 General disorders and admi
Asymptomatic localized n N/A 10054482 General disorders and admi
Moderate neck edema; slig N/A 10054482 General disorders and admi
Generalized neck edema (e.g N/A 10054482 General disorders and admi
A disorder characterized b Clarification 10062501 General disorders and admi
An unexpected cessation of Clarification 10042435 General disorders and admi
Asymptomatic; clinical or N/A 10051341 Hepatobiliary disorders
Symptomatic; altered GI fu N/A 10051341 Hepatobiliary disorders
Severely altered GI functio Clarification 10051341 Hepatobiliary disorders
Life-threatening consequen N/A 10051341 Hepatobiliary disorders
Death N/A 10051341 Hepatobiliary disorders
A disorder characterized b N/A 10051341 Hepatobiliary disorders
Symptomatic and intervent Clarification 10004665 Hepatobiliary disorders
Severely altered GI functi Clarification 10004665 Hepatobiliary disorders
Life-threatening consequen Clarification 10004665 Hepatobiliary disorders
A disorder characterized N/A 10004665 Hepatobiliary disorders
Symptomatic; medical inte N/A 10008612 Hepatobiliary disorders
Severe symptoms; radiologi Clarification 10008612 Hepatobiliary disorders
Asymptomatic clinical or d Clarification 10017631 Hepatobiliary disorders
Symptomatic and intervent Clarification 10017631 Hepatobiliary disorders
Symptomatic or severely al Clarification 10017631 Hepatobiliary disorders
A disorder characterized N/A 10017631 Hepatobiliary disorders
A disorder characterized by N/A 10059446 Hepatobiliary disorders
Asymptomatic; clinical or N/A 10017636 Hepatobiliary disorders
Symptomatic; altered GI fun N/A 10017636 Hepatobiliary disorders
Symptomatic and severely a N/A 10017636 Hepatobiliary disorders
Mild pain N/A 10017638 Hepatobiliary disorders
Moderate pain; limiting i N/A 10017638 Hepatobiliary disorders
Severe pain; limiting self N/A 10017638 Hepatobiliary disorders
Asterixis; mild encephalopa Clarification 10019663 Hepatobiliary disorders
Moderate to severe encep Clarification 10019663 Hepatobiliary disorders
A disorder characterized b Clarification 10019663 Hepatobiliary disorders
Mild; intervention not ind Clarification 10019678 Hepatobiliary disorders
Symptomatic; medical inte Clarification 10019678 Hepatobiliary disorders
Transfusion indicated Clarification 10019678 Hepatobiliary disorders
Mild pain N/A 10019705 Hepatobiliary disorders
Moderate pain; limiting i N/A 10019705 Hepatobiliary disorders
Severe pain; limiting self N/A 10019705 Hepatobiliary disorders
Asymptomatic or mild sympt N/A 10019805 Hepatobiliary disorders
Moderate; minimal, local o N/A 10019805 Hepatobiliary disorders
Severe or medically signifi Clarification 10019805 Hepatobiliary disorders
Radiologic, endoscopic or Clarification 10034405 Hepatobiliary disorders
Decreased portal vein flo N/A 10036200 Hepatobiliary disorders
Reversal/retrograde portal N/A 10036200 Hepatobiliary disorders
Intervention not indicated N/A 10036206 Hepatobiliary disorders
Medical intervention indi N/A 10036206 Hepatobiliary disorders
Transient flushing or rash Clarification 10001718 Immune system disorders
Intervention or infusion i Clarification 10001718 Immune system disorders
Prolonged (e.g., not rapid Clarification 10001718 Immune system disorders
Life-threatening consequen N/A 10001718 Immune system disorders
Death N/A 10001718 Immune system disorders
A disorder characterized b N/A 10001718 Immune system disorders
Symptomatic bronchospasm, N/A 10002218 Immune system disorders
Asymptomatic; serologic o N/A 10061664 Immune system disorders
Evidence of autoimmune rea N/A 10061664 Immune system disorders
Autoimmune reactions invol N/A 10061664 Immune system disorders
A disorder resulting from l Clarification 10061664 Immune system disorders
Mild reaction; infusion int Clarification 10052015 Immune system disorders
Therapy or infusion interr Clarification 10052015 Immune system disorders
Prolonged (e.g., not rapid Clarification 10052015 Immune system disorders
Life-threatening consequen Clarification 10052015 Immune system disorders
A disorder characterized b Clarification 10052015 Immune system disorders
Asymptomatic or mild sympt N/A 10021428 Immune system disorders
Moderate; minimal, local o N/A 10021428 Immune system disorders
Severe or medically signifi Clarification 10021428 Immune system disorders
Asymptomatic; clinical or N/A 10040400 Immune system disorders
Moderate arthralgia; fever, N/A 10040400 Immune system disorders
Severe arthralgia or arthrit N/A 10040400 Immune system disorders
IV antibiotic, antifungal, Clarification 10056519 Infections and infestations
Life-threatening consequen N/A 10056519 Infections and infestations
Death N/A 10056519 Infections and infestations
A disorder characterized b N/A 10056519 Infections and infestations
Localized; local interventi Clarification 10061640 Infections and infestations
Oral intervention indicated Clarification 10061640 Infections and infestations
A disorder characterized N/A 10003011 Infections and infestations
Severe symptoms; elective Clarification 10003012 Infections and infestations
Symptomatic; medical inte Deletion 10021881 Infections and infestations
A disorder characterized by N/A 10065744 Infections and infestations
Local infection with modera Clarification 10006259 Infections and infestations
Severe infection; axillary a Clarification 10006259 Infections and infestations
Moderate symptoms; oral int Clarification 10055078 Infections and infestations
Localized; local interventio Clarification 10007810 Infections and infestations
Localized; local interventio N/A 10008330 Infections and infestations
Death Deletion 10021881 Infections and infestations
Moderate symptoms; medical N/A 10065752 Infections and infestations
IV antibiotic, antifungal, N/A 10014594 Infections and infestations
Local intervention indicat N/A 10014801 Infections and infestations
Systemic intervention or h Clarification 10014801 Infections and infestations
Blindness (20/200 or wors Clarification 10014801 Infections and infestations
Passage of >3 unformed sto Clarification 10058838 Infections and infestations
Local intervention indicated N/A 10058804 Infections and infestations
Local therapy indicated (s N/A 10018784 Infections and infestations
Asymptomatic, treatment Clarification 10019799 Infections and infestations
Symptomatic liver dysfunct Clarification 10019799 Infections and infestations
Decompensated liver funct Clarification 10019799 Infections and infestations
Asymptomatic or mild sympt N/A 10021881 Infections and infestations
Moderate; minimal, local o N/A 10021881 Infections and infestations
Severe or medically signifi Clarification 10021881 Infections and infestations
Arthroscopic intervention i N/A 10023216 Infections and infestations
Localized, local interventi N/A 10065755 Infections and infestations
A disorder characterized by Clarification 10061229 Infections and infestations
IV antibiotic, antifungal, o Clarification 10027199 Infections and infestations
Localized; local interventio Deletion 10033072 Infections and infestations
Papules and/or pustules c N/A 10069138 Infections and infestations
Papules and/or pustules c Clarification 10069138 Infections and infestations
Papules and/or pustules co Clarification 10069138 Infections and infestations
Papules and/or pustules co Clarification 10069138 Infections and infestations
Nail fold edema or erythem N/A 10034016 Infections and infestations
Localized intervention indi Clarification 10034016 Infections and infestations
Surgical intervention or IV Clarification 10034016 Infections and infestations
Mild; non-surgical interve Clarification 10002544 Injury, poisoning and proc
Limiting instrumental ADL; Clarification 10002544 Injury, poisoning and proc
Limiting self care ADL; ele Clarification 10002544 Injury, poisoning and proc
A finding of damage to the N/A 10002544 Injury, poisoning and proc
Severe symptoms; limiting s Clarification 10002899 Injury, poisoning and proc
Life-threatening conseque N/A 10002899 Injury, poisoning and proc
Death N/A 10002899 Injury, poisoning and proc
Asymptomatic diagnostic fi N/A 10003162 Injury, poisoning and proc
Symptomatic (e.g., claudica Clarification 10003162 Injury, poisoning and proc
A finding of damage to an N/A 10003162 Injury, poisoning and proc
Asymptomatic diagnostic o Clarification 10050458 Injury, poisoning and proc
Symptomatic; medical inte N/A 10050458 Injury, poisoning and proc
Severe symptoms; radiologi Clarification 10050458 Injury, poisoning and proc
Life-threatening consequen N/A 10050458 Injury, poisoning and proc
A finding of leakage of bi N/A 10050458 Injury, poisoning and proc
A finding of leakage of ur N/A 10065802 Injury, poisoning and proc
Localized or in a dependen N/A 10006504 Injury, poisoning and proc
Generalized N/A 10006504 Injury, poisoning and proc
A finding of injury of the N/A 10006504 Injury, poisoning and proc
Minimal symptoms; interve N/A 10006634 Injury, poisoning and proc
Medical intervention; min N/A 10006634 Injury, poisoning and proc
Moderate to major debride N/A 10006634 Injury, poisoning and proc
A finding of impaired inte N/A 10006634 Injury, poisoning and proc
Faint erythema or dry de N/A 10061103 Injury, poisoning and proc
Moderate to brisk erythem N/A 10061103 Injury, poisoning and proc
Moist desquamation in are N/A 10061103 Injury, poisoning and proc
A finding of cutaneous infl N/A 10061103 Injury, poisoning and proc
A finding of leakage due N/A 10065961 Injury, poisoning and proc
Minor with no resultant in N/A 10016173 Injury, poisoning and proc
Symptomatic; noninvasive N/A 10016173 Injury, poisoning and proc
Hospitalization indicated Clarification 10016173 Injury, poisoning and proc
A finding of sudden movem N/A 10016173 Injury, poisoning and proc
Asymptomatic; clinical or N/A 10065788 Injury, poisoning and proc
A finding of leakage due t N/A 10065788 Injury, poisoning and proc
Asymptomatic diagnostic o Deletion 10022117 Injury, poisoning and proc
Symptomatic and intervent Clarification 10065790 Injury, poisoning and proc
Severe symptoms; elective Clarification 10065790 Injury, poisoning and proc
A finding of rupture of the Clarification 10065790 Injury, poisoning and proc
Symptomatic but non-displ N/A 10017076 Injury, poisoning and proc
Severe symptoms; displace Clarification 10017076 Injury, poisoning and proc
A finding of traumatic inju N/A 10017076 Injury, poisoning and proc
Superficial necrosis; inter N/A 10065712 Injury, poisoning and proc
Severe symptoms; hospitali Clarification 10065712 Injury, poisoning and proc
A finding of a necrotic pro Clarification 10065712 Injury, poisoning and proc
Hairline fracture; mild pai Clarification 10020100 Injury, poisoning and proc
Severe pain; hospitalizatio N/A 10020100 Injury, poisoning and proc
Life-threatening consequ N/A 10020100 Injury, poisoning and proc
Severe symptoms; limiting s N/A 10022161 Injury, poisoning and proc
Symptomatic limiting self c Clarification 10065849 Injury, poisoning and proc
Symptomatic; repair or rev N/A 10022356 Injury, poisoning and proc
Life-threatening conseque Clarification 10022356 Injury, poisoning and proc
Asymptomatic or mild sympt N/A 10022117 Injury, poisoning and proc
Moderate; minimal, local o N/A 10022117 Injury, poisoning and proc
Severe or medically signifi Clarification 10022117 Injury, poisoning and proc
A finding of leakage of co N/A 10059095 Injury, poisoning and proc
Self-limited; intervention N/A 10059094 Injury, poisoning and proc
Severe symptoms; IV fluids N/A 10059094 Injury, poisoning and proc
A finding of blockage of th Clarification 10059094 Injury, poisoning and proc
Minimal bleeding identifie N/A 10049468 Injury, poisoning and proc
Moderate bleeding; medica N/A 10049468 Injury, poisoning and proc
Severe bleeding; transfusi Clarification 10049468 Injury, poisoning and proc
A finding of blood leakage Clarification 10049468 Injury, poisoning and proc
Primary repair of injured N/A 10065826 Injury, poisoning and proc
Partial resection of injure N/A 10065826 Injury, poisoning and proc
Complete resection or reco Clarification 10065826 Injury, poisoning and proc
A finding of damage to an N/A 10065826 Injury, poisoning and proc
A finding of damage to th N/A 10065831 Injury, poisoning and proc
Complete resection of inju Clarification 10065844 Injury, poisoning and proc
Postoperative radiologic, Clarification 10055298 Injury, poisoning and proc
A finding of uncontrolled N/A 10055298 Injury, poisoning and proc
Primary repair of injured Deletion 10022117 Injury, poisoning and proc
Partial resection of injure Deletion 10022117 Injury, poisoning and proc
Complete resection or reco Deletion 10022117 Injury, poisoning and proc
Life-threatening consequen Deletion 10022117 Injury, poisoning and proc
Death Deletion 10022117 Injury, poisoning and proc
A finding of damage to the Deletion 10022117 Injury, poisoning and proc
Resection or reconstructio Clarification 10065847 Injury, poisoning and proc
A finding of damage to a v N/A 10065848 Injury, poisoning and proc
A finding of leakage of ur N/A 10065803 Injury, poisoning and proc
Minimal bleeding identifie Clarification 10055322 Injury, poisoning and proc
Moderate bleeding; radiolo Clarification 10055322 Injury, poisoning and proc
Transfusion indicated of > Clarification 10055322 Injury, poisoning and proc
A finding of bleeding occur Clarification 10055322 Injury, poisoning and proc
Extubated within 24 - 72 h N/A 10056745 Injury, poisoning and proc
Extubated >72 hrs postope N/A 10056745 Injury, poisoning and proc
Life-threatening airway co N/A 10056745 Injury, poisoning and proc
A finding of a previously N/A 10056745 Injury, poisoning and proc
Asymptomatic; reducible N/A 10065745 Injury, poisoning and proc
Recurrent after manual redu N/A 10065745 Injury, poisoning and proc
Severe symptoms; elective N/A 10065745 Injury, poisoning and proc
A finding of protrusion of N/A 10065745 Injury, poisoning and proc
Local care or maintenance; N/A 10065822 Injury, poisoning and proc
Dysfunctional stoma; elect N/A 10065822 Injury, poisoning and proc
A finding of displacement N/A 10065822 Injury, poisoning and proc
Faint erythema or dry de N/A 10037767 Injury, poisoning and proc
Moderate to brisk erythem N/A 10037767 Injury, poisoning and proc
Moist desquamation in are N/A 10037767 Injury, poisoning and proc
A finding of acute skin in N/A 10037767 Injury, poisoning and proc
Symptomatic; simple aspir N/A 10040102 Injury, poisoning and proc
Symptomatic, elective radi Clarification 10040102 Injury, poisoning and proc
A finding of tumor-like col N/A 10040102 Injury, poisoning and proc
Mild back pain; nonprescri N/A 10041569 Injury, poisoning and proc
Moderate back pain; prescr N/A 10041569 Injury, poisoning and proc
Severe back pain; hospitaliz N/A 10041569 Injury, poisoning and proc
Life-threatening consequ N/A 10041569 Injury, poisoning and proc
Symptomatic; IV fluids ind N/A 10065898 Injury, poisoning and proc
Severely altered GI functio N/A 10065898 Injury, poisoning and proc
A finding of narrowing of N/A 10065898 Injury, poisoning and proc
Severe symptoms; elective N/A 10042127 Injury, poisoning and proc
A disorder characterized b Clarification 10042127 Injury, poisoning and proc
Minimal bleeding identifie Clarification 10062548 Injury, poisoning and proc
Moderate bleeding; medica Clarification 10062548 Injury, poisoning and proc
A finding of bleeding from Clarification 10062548 Injury, poisoning and proc
Partial asymptomatic obstr N/A 10044291 Injury, poisoning and proc
Symptomatic (e.g., noisy ai N/A 10044291 Injury, poisoning and proc
Stridor; radiologic or endos Clarification 10044291 Injury, poisoning and proc
Life-threatening airway co N/A 10044291 Injury, poisoning and proc
A finding of blockage of t Clarification 10044291 Injury, poisoning and proc
A finding of blood leakage Clarification 10065749 Injury, poisoning and proc
A finding of leakage of co N/A 10065882 Injury, poisoning and proc
Symptomatic; dilation or e N/A 10065883 Injury, poisoning and proc
Altered organ function (e.g N/A 10065883 Injury, poisoning and proc
A finding of blockage of t Clarification 10065883 Injury, poisoning and proc
A finding of bleeding from Clarification 10065748 Injury, poisoning and proc
Symptomatic but no hydrone Clarification 10065885 Injury, poisoning and proc
Symptomatic (e.g., hydrone N/A 10065885 Injury, poisoning and proc
A finding of narrowing of N/A 10065885 Injury, poisoning and proc
Asymptomatic diagnostic o Deletion 10022117 Injury, poisoning and proc
Symptomatic and intervent Clarification 10046810 Injury, poisoning and proc
Severe symptoms; elective Clarification 10046810 Injury, poisoning and proc
A disorder characterized by N/A 10046810 Injury, poisoning and proc
Device dislodgement, block N/A 10062169 Injury, poisoning and proc
Deep vein or cardiac thromb Clarification 10062169 Injury, poisoning and proc
Embolic event including p Clarification 10062169 Injury, poisoning and proc
A finding of a previously N/A 10062169 Injury, poisoning and proc
Symptomatic (e.g., claudica N/A 10047228 Injury, poisoning and proc
A finding of damage to a v N/A 10047228 Injury, poisoning and proc
Incisional separation of < Clarification 10053692 Injury, poisoning and proc
Incisional separation >25% Clarification 10053692 Injury, poisoning and proc
Hernia without evidence of Clarification 10053692 Injury, poisoning and proc
Hernia with evidence of st Clarification 10053692 Injury, poisoning and proc
A finding of development o N/A 10053692 Injury, poisoning and proc
Incisional separation of < Clarification 10048031 Injury, poisoning and proc
Incisional separation >25 Clarification 10048031 Injury, poisoning and proc
Fascial disruption or dehi Clarification 10048031 Injury, poisoning and proc
A finding of separation of N/A 10048031 Injury, poisoning and proc
Mild; non-surgical interve Clarification 10048049 Injury, poisoning and proc
Limiting instrumental ADL; Clarification 10048049 Injury, poisoning and proc
Limiting self care ADL; ele Clarification 10048049 Injury, poisoning and proc
>ULN - 1.5 x ULN N/A 10000636 Investigations
>1.5 - 2.5 x ULN N/A 10000636 Investigations
>2.5 x ULN; hemorrhage Clarification 10000636 Investigations
An abnormal laboratory tes Clarification 10000636 Investigations
>ULN - 3.0 x ULN Clarification 10001551 Investigations
>3.0 - 5.0 x ULN Clarification 10001551 Investigations
>20.0 x ULN Clarification 10001551 Investigations
A finding based on laborat N/A 10001551 Investigations
A finding based on laborato N/A 10001675 Investigations
Asymptomatic; clinical or N/A 10005332 Investigations
Symptomatic; medical inte N/A 10005332 Investigations
Hospitalization indicated N/A 10005332 Investigations
Symptomatic; medical inte N/A 10005452 Investigations
Hospitalization indicated N/A 10005452 Investigations
Symptomatic; medical inter N/A 10005561 Investigations
Severe symptoms; limiting N/A 10005561 Investigations
Moderate symptoms; limit N/A 10005778 Investigations
3 - 5 units below LLN; for Clarification 10065906 Investigations
6 - 8 units below LLN; for Clarification 10065906 Investigations
Asymptomatic decrease of Clarification 10065906 Investigations
A finding based on lung fu N/A 10065906 Investigations
Levels above the upper lim N/A 10007612 Investigations
Levels consistent with myo N/A 10007612 Investigations
A laboratory test result wh Clarification 10007612 Investigations
Levels above the upper lim N/A 10007613 Investigations
Levels consistent with myo N/A 10007613 Investigations
A laboratory test result wh Clarification 10007613 Investigations
<LLN - 500/mm3; <LLN - 0 N/A 10007839 Investigations
<500 - 200/mm3; <0.5 - 0. N/A 10007839 Investigations
<200 - 50/mm3; <0.2 x 0.0 N/A 10007839 Investigations
<50/mm3; <0.05 x 10e9 /L N/A 10007839 Investigations
>ULN - 300 mg/dL; >ULN - N/A 10008661 Investigations
>300 - 400 mg/dL; >7.75 - N/A 10008661 Investigations
>400 - 500 mg/dL; >10.34 N/A 10008661 Investigations
>500 mg/dL; >12.92 mmol N/A 10008661 Investigations
>2.5 x ULN - 5 x ULN N/A 10011268 Investigations
>5 x ULN - 10 x ULN N/A 10011268 Investigations
>10 x ULN N/A 10011268 Investigations
>1 - 1.5 x baseline; >ULN - Clarification 10011368 Investigations
>1.5 - 3.0 x baseline; >1.5 N/A 10011368 Investigations
>3.0 baseline; >3.0 - 6.0 x Clarification 10011368 Investigations
>6.0 x ULN N/A 10011368 Investigations
Resting ejection fraction N/A 10050528 Investigations
Resting ejection fraction Clarification 10050528 Investigations
Resting ejection fraction N/A 10050528 Investigations
The percentage computed w N/A 10050528 Investigations
QTc 450 - 480 ms Clarification 10014383 Investigations
QTc 481 - 500 ms Clarification 10014383 Investigations
QTc >= 501 ms on at least Clarification 10014383 Investigations
QTc >= 501 or >60 ms chan Clarification 10014383 Investigations
A finding of a cardiac dys N/A 10014383 Investigations
<1.0 - 0.75 x LLN or <25% Clarification 10016596 Investigations
<0.75 - 0.5 x LLN or 25 - Clarification 10016596 Investigations
<0.5 - 0.25 x LLN or 50 - Clarification 10016596 Investigations
<0.25 x LLN or 75% decre Clarification 10016596 Investigations
FEV1% (percentages of obse N/A 10016987 Investigations
FEV1 60 - 69% N/A 10016987 Investigations
50 - 59% N/A 10016987 Investigations
<= 49% N/A 10016987 Investigations
A finding based on test res N/A 10016987 Investigations
A finding based on labora N/A 10056910 Investigations
Symptomatic; medical inter N/A 10018748 Investigations
<LLN N/A 10019150 Investigations
Increase in >0 - 2 gm/dL a Clarification 10055599 Investigations
Increase in >2 - 4 gm/dL a Clarification 10055599 Investigations
Increase in >4 gm/dL above Clarification 10055599 Investigations
A finding based on laborato Clarification 10055599 Investigations
>1 - 1.5 x ULN; >1 - 1.5 ti Clarification 10022402 Investigations
>1.5 - 2.5 x ULN; >1.5 - 2. Clarification 10022402 Investigations
>2.5 x ULN; >2.5 times abo Clarification 10022402 Investigations
Asymptomatic or mild sympt N/A 10022891 Investigations
Moderate; minimal, local o N/A 10022891 Investigations
Severe or medically signifi Clarification 10022891 Investigations
Life-threatening consequen N/A 10022891 Investigations
Death N/A 10022891 Investigations
>4000/mm3 - 20,000/mm N/A 10025258 Investigations
>20,000/mm3 N/A 10025258 Investigations
<1500 - 1000/mm3; <1.5 - N/A 10029366 Investigations
<1000 - 500/mm3; <1.0 - 0 N/A 10029366 Investigations
<LLN and asymptomatic N/A 10062646 Investigations
Increase in stool frequency N/A 10062646 Investigations
Sequelae of absorption de N/A 10062646 Investigations
<LLN - 75,000/mm3; <LLN - N/A 10035528 Investigations
<75,000 - 50,000/mm3; <75 N/A 10035528 Investigations
<50,000 - 25,000/mm3; <50 N/A 10035528 Investigations
<25,000/mm3; <25.0 x 10e N/A 10035528 Investigations
Oliguria (<80 ml in 8 hr) Clarification 10059895 Investigations
Anuria (<240 ml in 24 hr) Clarification 10059895 Investigations
A finding based on test res N/A 10059895 Investigations
90 - 75% of predicted valu N/A 10047580 Investigations
<75 - 50% of predicted val N/A 10047580 Investigations
<50% of predicted value; l N/A 10047580 Investigations
A finding based on pulmona N/A 10047580 Investigations
5 - <10% from baseline N/A 10047896 Investigations
10 - <20% from baseline N/A 10047896 Investigations
>=20% from baseline N/A 10047896 Investigations
A finding characterized by Clarification 10047896 Investigations
5 to <10% from baseline; i N/A 10047900 Investigations
10 - <20% from baseline; n N/A 10047900 Investigations
>=20% from baseline; tube N/A 10047900 Investigations
A finding characterized by N/A 10047900 Investigations
<1000/mm3; <1.0 x 10e9 / N/A 10049182 Investigations
pH <normal, but >=7.3 N/A 10000486 Metabolism and nutrition
pH <7.3 N/A 10000486 Metabolism and nutrition
Life-threatening conseque N/A 10000486 Metabolism and nutrition
Death N/A 10000486 Metabolism and nutrition
A disorder characterized b N/A 10000486 Metabolism and nutrition
Present N/A 10001598 Metabolism and nutrition
Severe symptoms; limiting N/A 10001598 Metabolism and nutrition
Life-threatening consequen N/A 10001598 Metabolism and nutrition
pH >normal, but <=7.5 N/A 10001680 Metabolism and nutrition
pH >7.5 N/A 10001680 Metabolism and nutrition
Life-threatening conseque N/A 10001680 Metabolism and nutrition
Loss of appetite without al N/A 10002646 Metabolism and nutrition
Oral intake altered without N/A 10002646 Metabolism and nutrition
Associated with significant N/A 10002646 Metabolism and nutrition
A disorder characterized by N/A 10002646 Metabolism and nutrition
Increased oral fluids ind N/A 10012174 Metabolism and nutrition
IV fluids indicated <24 hrs Clarification 10012174 Metabolism and nutrition
IV fluids or hospitalization Clarification 10012174 Metabolism and nutrition
Asymptomatic; clinical or N/A 10052426 Metabolism and nutrition
Symptomatic; dietary modif N/A 10052426 Metabolism and nutrition
Severe symptoms; insulin N/A 10052426 Metabolism and nutrition
Corrected serum calcium o N/A 10020587 Metabolism and nutrition
Corrected serum calcium of N/A 10020587 Metabolism and nutrition
Fasting glucose value >UL Clarification 10020639 Metabolism and nutrition
Fasting glucose value >160 Clarification 10020639 Metabolism and nutrition
>250 - 500 mg/dL; >13.9 - Clarification 10020639 Metabolism and nutrition
>500 mg/dL; >27.8 mmol/L; Clarification 10020639 Metabolism and nutrition
>ULN - 5.5 mmol/L N/A 10020647 Metabolism and nutrition
>5.5 - 6.0 mmol/L Clarification 10020647 Metabolism and nutrition
>6.0 - 7.0 mmol/L; hospita N/A 10020647 Metabolism and nutrition
>7.0 mmol/L; life-threate N/A 10020647 Metabolism and nutrition
>ULN - 3.0 mg/dL; >ULN - N/A 10020670 Metabolism and nutrition
>3.0 - 8.0 mg/dL; >1.23 - N/A 10020670 Metabolism and nutrition
>8.0 mg/dL; >3.30 mmol/L; N/A 10020670 Metabolism and nutrition
>ULN - 150 mmol/L N/A 10020680 Metabolism and nutrition
>150 - 155 mmol/L Clarification 10020680 Metabolism and nutrition
>155 - 160 mmol/L; hospita N/A 10020680 Metabolism and nutrition
>160 mmol/L; life-threat N/A 10020680 Metabolism and nutrition
150 mg/dL - 300 mg/dL; 1 N/A 10020870 Metabolism and nutrition
>300 mg/dL - 500 mg/dL; N/A 10020870 Metabolism and nutrition
>500 mg/dL - 1000 mg/dL; N/A 10020870 Metabolism and nutrition
>1000 mg/dL; >11.4 mmol/L N/A 10020870 Metabolism and nutrition
>ULN - 10 mg/dL (0.59 mm Clarification 10020907 Metabolism and nutrition
>ULN - 10 mg/dL (0.59 mmo Clarification 10020907 Metabolism and nutrition
>10 mg/dL; >0.59 mmol/L; Clarification 10020907 Metabolism and nutrition
<LLN - 3 g/dL; <LLN - 30 g/ N/A 10020943 Metabolism and nutrition
<3 - 2 g/dL; <30 - 20 g/L N/A 10020943 Metabolism and nutrition
<2 g/dL; <20 g/L N/A 10020943 Metabolism and nutrition
<LLN - 55 mg/dL; <LLN - 3 N/A 10021005 Metabolism and nutrition
<55 - 40 mg/dL; <3.0 - 2. N/A 10021005 Metabolism and nutrition
<40 - 30 mg/dL; <2.2 - 1. N/A 10021005 Metabolism and nutrition
<30 mg/dL; <1.7 mmol/L; l N/A 10021005 Metabolism and nutrition
<LLN - 3.0 mmol/L N/A 10021018 Metabolism and nutrition
<LLN - 3.0 mmol/L; sympto Clarification 10021018 Metabolism and nutrition
<3.0 - 2.5 mmol/L; hospita N/A 10021018 Metabolism and nutrition
<2.5 mmol/L; life-threate N/A 10021018 Metabolism and nutrition
<LLN - 1.2 mg/dL; <LLN - N/A 10021028 Metabolism and nutrition
<1.2 - 0.9 mg/dL; <0.5 - 0 N/A 10021028 Metabolism and nutrition
<0.9 - 0.7 mg/dL; <0.4 - 0 N/A 10021028 Metabolism and nutrition
<0.7 mg/dL; <0.3 mmol/L; N/A 10021028 Metabolism and nutrition
<LLN - 130 mmol/L N/A 10021038 Metabolism and nutrition
<130 - 120 mmol/L Clarification 10021038 Metabolism and nutrition
<120 mmol/L; life-threat N/A 10021038 Metabolism and nutrition
<LLN - 2.5 mg/dL; <LLN - Clarification 10021059 Metabolism and nutrition
<2.5 - 2.0 mg/dL; <0.8 - 0 Clarification 10021059 Metabolism and nutrition
<2.0 - 1.0 mg/dL; <0.6 - 0 Clarification 10021059 Metabolism and nutrition
<1.0 mg/dL; <0.3 mmol/L; Clarification 10021059 Metabolism and nutrition
Moderate symptoms; inter N/A 10065973 Metabolism and nutrition
Severe symptoms; interven N/A 10065973 Metabolism and nutrition
Asymptomatic or mild sympt N/A 10027433 Metabolism and nutrition
Moderate; minimal, local o N/A 10027433 Metabolism and nutrition
Severe or medically signifi Clarification 10027433 Metabolism and nutrition
BMI 25 - 29.9 kg/m2 N/A 10029883 Metabolism and nutrition
BMI 30 - 39.9 kg/m2 N/A 10029883 Metabolism and nutrition
BMI >=40 kg/m2 N/A 10029883 Metabolism and nutrition
Present N/A 10045152 Metabolism and nutrition
Local wound care; medical N/A 10065775 Musculoskeletal and conne
Operative debridement or ot Clarification 10065775 Musculoskeletal and conne
Life-threatening consequen N/A 10065775 Musculoskeletal and conne
Death N/A 10065775 Musculoskeletal and conne
A disorder characterized by N/A 10065775 Musculoskeletal and conne
Mild pain N/A 10003239 Musculoskeletal and conne
Moderate pain; limiting i N/A 10003239 Musculoskeletal and conne
Severe pain; limiting self N/A 10003239 Musculoskeletal and conne
A disorder characterized b N/A 10003239 Musculoskeletal and conne
Mild pain with inflammatio N/A 10003246 Musculoskeletal and conne
Moderate pain associated w N/A 10003246 Musculoskeletal and conne
Severe pain associated with Clarification 10003246 Musculoskeletal and conne
Asymptomatic; clinical or N/A 10066480 Musculoskeletal and conne
Symptomatic; limiting ins N/A 10066480 Musculoskeletal and conne
Severe symptoms; limiting N/A 10066480 Musculoskeletal and conne
A disorder characterized b Clarification 10003988 Musculoskeletal and conne
A disorder characterized Clarification 10006002 Musculoskeletal and conne
A disorder characterized N/A 10015688 Musculoskeletal and conne
Mild induration, able to mo N/A 10065799 Musculoskeletal and conne
Moderate induration, able t N/A 10065799 Musculoskeletal and conne
Severe induration; unable t Clarification 10065799 Musculoskeletal and conne
Generalized; associated w N/A 10065799 Musculoskeletal and conne
Symptomatic; weakness per Clarification 10062572 Musculoskeletal and conne
Symptomatic; weakness evi Clarification 10062572 Musculoskeletal and conne
Weakness limiting self car Clarification 10062572 Musculoskeletal and conne
Reduction in growth veloci N/A 10018761 Musculoskeletal and conne
Severe symptoms; limiting Clarification 10023215 Musculoskeletal and conne
<=25% loss of ROM (range o N/A 10048706 Musculoskeletal and conne
>25 - 50% decrease in ROM N/A 10048706 Musculoskeletal and conne
>50% decrease in ROM; limi Clarification 10048706 Musculoskeletal and conne
Mild restriction of rotatio N/A 10065796 Musculoskeletal and conne
Rotation <60 degrees to rig N/A 10065796 Musculoskeletal and conne
Ankylosed/fused over mult N/A 10065796 Musculoskeletal and conne
Stiffness; difficulty bendin N/A 10065800 Musculoskeletal and conne
Pain with range of motion N/A 10065800 Musculoskeletal and conne
<50% lumbar spine flexion; N/A 10065800 Musculoskeletal and conne
Moderate accentuation; li N/A 10023509 Musculoskeletal and conne
Severe accentuation; opera N/A 10023509 Musculoskeletal and conne
Moderate accentuation; li N/A 10024842 Musculoskeletal and conne
Severe accentuation; opera N/A 10024842 Musculoskeletal and conne
Symptomatic; perceived byPrimary SOC change 10065780 Nervous system disorders
Symptomatic; evident on pPrimary SOC change 10065780 Nervous system disorders
Limiting self care ADL;
Clarification,
dis Primary SOC change
10065780 Nervous system disorders
A disorder characterized byPrimary SOC change 10065780 Nervous system disorders
Symptomatic; perceived by N/A 10065776 Musculoskeletal and conne
Symptomatic; evident on p N/A 10065776 Musculoskeletal and conne
Limiting self care ADL; dis Clarification 10065776 Musculoskeletal and conne
Symptomatic; perceived byPrimary SOC change 10065794 Nervous system disorders
Symptomatic; evident on pPrimary SOC change 10065794 Nervous system disorders
Limiting self care ADL;
Clarification,
dis Primary SOC change
10065794 Nervous system disorders
A disorder characterized byPrimary SOC change 10065794 Nervous system disorders
Asymptomatic or mild sympt N/A 10028395 Musculoskeletal and conne
Moderate; minimal, local o N/A 10028395 Musculoskeletal and conne
Severe or medically signifi Clarification 10028395 Musculoskeletal and conne
Cosmetically and functional N/A 10065783 Musculoskeletal and conne
Deformity, hypoplasia, or N/A 10065783 Musculoskeletal and conne
Significant deformity, hyp Clarification 10065783 Musculoskeletal and conne
Moderate pain associated N/A 10028653 Musculoskeletal and conne
Pain associated with sever N/A 10028653 Musculoskeletal and conne
Symptomatic; medical inter N/A 10064658 Musculoskeletal and conne
Radiologic evidence of ost Clarification 10031282 Musculoskeletal and conne
BMD t-score <-2.5; loss of Clarification 10031282 Musculoskeletal and conne
Loss of height >=2 cm; hosp Clarification 10031282 Musculoskeletal and conne
<20 degrees; clinically un N/A 10039722 Musculoskeletal and conne
>20 - 45 degrees; visible b N/A 10039722 Musculoskeletal and conne
>45 degrees; scapular prom Clarification 10039722 Musculoskeletal and conne
Mild induration, able to mo N/A 10065798 Musculoskeletal and conne
Moderate induration, able t N/A 10065798 Musculoskeletal and conne
Severe induration; unable t N/A 10065798 Musculoskeletal and conne
Generalized; associated w N/A 10065798 Musculoskeletal and conne
Decreased ROM (range of N/A 10044684 Musculoskeletal and conne
Decreased ROM requiring sm N/A 10044684 Musculoskeletal and conne
Decreased ROM with inabili N/A 10044684 Musculoskeletal and conne
Mild length discrepancy < N/A 10065738 Musculoskeletal and conne
Moderate length discrepanc N/A 10065738 Musculoskeletal and conne
Severe length discrepancy Clarification 10065738 Musculoskeletal and conne
Present N/A 10048293 Neoplasms benign, malignan
Death N/A 10048293 Neoplasms benign, malignan
A disorder characterized b N/A 10048293 Neoplasms benign, malignan
Life-threatening consequen N/A 10028533 Neoplasms benign, malignan
Asymptomatic or mild sympt N/A 10029104 Neoplasms benign, malignan
Moderate; minimal, local o N/A 10029104 Neoplasms benign, malignan
Severe or medically signifi Clarification 10029104 Neoplasms benign, malignan
Life-threatening consequen N/A 10029104 Neoplasms benign, malignan
Non life-threatening seco N/A 10049737 Neoplasms benign, malignan
Acute life-threatening sec N/A 10049737 Neoplasms benign, malignan
Mild pain N/A 10045158 Neoplasms benign, malignan
Moderate pain; limiting i N/A 10045158 Neoplasms benign, malignan
Severe pain; limiting self N/A 10045158 Neoplasms benign, malignan
A disorder characterized b Clarification 10045158 Neoplasms benign, malignan
Asymptomatic; clinical or N/A 10053662 Nervous system disorders
Moderate symptoms; limit N/A 10053662 Nervous system disorders
Severe symptoms; limiting N/A 10053662 Nervous system disorders
A disorder characterized b Clarification 10053662 Nervous system disorders
Mild restlessness or incre N/A 10001540 Nervous system disorders
Moderate restlessness or i N/A 10001540 Nervous system disorders
Severe restlessness or incr N/A 10001540 Nervous system disorders
A disorder characterized by N/A 10001540 Nervous system disorders
Mild; transient memory lo N/A 10001949 Nervous system disorders
Moderate; short term memo N/A 10001949 Nervous system disorders
Severe; long term memory l N/A 10001949 Nervous system disorders
A disorder characterized b N/A 10001949 Nervous system disorders
Voicelessness; unable to N/A 10002953 Nervous system disorders
Mild symptoms N/A 10003074 Nervous system disorders
Life-threatening consequen N/A 10003074 Nervous system disorders
Death N/A 10003074 Nervous system disorders
A disorder characterized N/A 10003074 Nervous system disorders
Moderate symptoms; cortic N/A 10065784 Nervous system disorders
Severe symptoms; medical N/A 10065784 Nervous system disorders
Post-craniotomy: asymptom N/A 10008164 Nervous system disorders
Post-craniotomy: moderate N/A 10008164 Nervous system disorders
Severe symptoms; medical N/A 10008164 Nervous system disorders
Mild cognitive disability; N/A 10009845 Nervous system disorders
Moderate cognitive disabil N/A 10009845 Nervous system disorders
Severe cognitive disabilit N/A 10009845 Nervous system disorders
Mild inattention or decrea N/A 10010250 Nervous system disorders
Moderate impairment in att N/A 10010250 Nervous system disorders
Severe impairment in atten N/A 10010250 Nervous system disorders
Decreased level of alertne N/A 10012373 Nervous system disorders
Sedation; slow response to N/A 10012373 Nervous system disorders
Difficult to arouse N/A 10012373 Nervous system disorders
Life-threatening conseque Clarification 10012373 Nervous system disorders
Mild unsteadiness or sen N/A 10013573 Nervous system disorders
Moderate unsteadiness or N/A 10013573 Nervous system disorders
Severe unsteadiness or sen N/A 10013573 Nervous system disorders
Mild slurred speech N/A 10013887 Nervous system disorders
Moderate impairment of ar N/A 10013887 Nervous system disorders
Severe impairment of artic N/A 10013887 Nervous system disorders
Mild sensory alteration N/A 10062872 Nervous system disorders
Moderate sensory alteratio N/A 10062872 Nervous system disorders
Severe sensory alteration; N/A 10062872 Nervous system disorders
Altered taste but no chang N/A 10013911 Nervous system disorders
Altered taste with change i N/A 10013911 Nervous system disorders
Awareness of receptive or N/A 10013951 Nervous system disorders
Moderate receptive or expr N/A 10013951 Nervous system disorders
Severe receptive or express N/A 10013951 Nervous system disorders
Mild involuntary movemen N/A 10015832 Nervous system disorders
Moderate involuntary mov N/A 10015832 Nervous system disorders
Severe involuntary movement N/A 10015832 Nervous system disorders
Mild pain N/A 10019211 Nervous system disorders
Moderate pain; limiting i N/A 10019211 Nervous system disorders
Severe pain; limiting self N/A 10019211 Nervous system disorders
Moderate symptoms; inter N/A 10020508 Nervous system disorders
Severe symptoms or neurolo N/A 10020508 Nervous system disorders
Mild increased need for sl N/A 10020765 Nervous system disorders
Moderate increased need f N/A 10020765 Nervous system disorders
Severe increased need for N/A 10020765 Nervous system disorders
Moderate symptoms; medic Clarification 10022763 Nervous system disorders
Ventriculostomy, ICP monit Clarification 10022763 Nervous system disorders
Moderate symptoms N/A 10023030 Nervous system disorders
Asymptomatic; clinical or Deletion 10074765 Nervous system disorders
Moderate symptoms; limit Deletion 10074765 Nervous system disorders
Severe symptoms; limiting Deletion 10074765 Nervous system disorders
A disorder characterized b Deletion 10074765 Nervous system disorders
Mild symptoms; reduced a N/A 10024264 Nervous system disorders
Asymptomatic; small focal N/A 10024382 Nervous system disorders
Moderate symptoms; focal N/A 10024382 Nervous system disorders
Severe symptoms; extensive N/A 10024382 Nervous system disorders
Mild memory impairment N/A 10027175 Nervous system disorders
Moderate memory impairme N/A 10027175 Nervous system disorders
Severe memory impairment; N/A 10027175 Nervous system disorders
Asymptomatic; mild signs (e Primary SOC change 10028524 Infections and infestations
Moderate weakness or sens Primary SOC change 10028524 Infections and infestations
Severe weakness or sensory Primary SOC change 10028524 Infections and infestations
Life-threatening consequenPrimary SOC change 10028524 Infections and infestations
Death Primary SOC change 10028524 Infections and infestations
A disorder characterized b Primary SOC change 10028524 Infections and infestations
Asymptomatic or mild sympt N/A 10029205 Nervous system disorders
Moderate; minimal, local o N/A 10029205 Nervous system disorders
Severe or medically signifi Clarification 10029205 Nervous system disorders
A disorder characterized by Clarification 10056388 Nervous system disorders
Asymptomatic; clinical or Clarification 10034580 Nervous system disorders
Severe symptoms; limiting Clarification 10034580 Nervous system disorders
A disorder characterized Clarification 10034580 Nervous system disorders
Asymptomatic; loss of dee Clarification 10034620 Nervous system disorders
Death Deletion 10029205 Nervous system disorders
Present (e.g., near fainting N/A 10036653 Nervous system disorders
Moderate symptoms; limiti Clarification 10061928 Nervous system disorders
Moderate symptoms N/A 10038130 Nervous system disorders
Severe symptoms; medical i N/A 10038130 Nervous system disorders
Asymptomatic; clinical or Deletion 10029205 Nervous system disorders
Moderate symptoms; abnorm Clarification 10063761 Nervous system disorders
Severe symptoms; very abn Clarification 10063761 Nervous system disorders
Life-threatening consequen Clarification 10063761 Nervous system disorders
Brief partial seizure; no l Clarification 10039906 Nervous system disorders
Brief generalized seizure N/A 10039906 Nervous system disorders
Multiple seizures despite Clarification 10039906 Nervous system disorders
Life-threatening; prolonge Clarification 10039906 Nervous system disorders
Mild pain Primary SOC change 10040747 Respiratory, thoracic and
Moderate pain; limiting i Primary SOC change 10040747 Respiratory, thoracic and
Severe pain; limiting self Primary SOC change 10040747 Respiratory, thoracic and
A disorder characterized b Primary SOC change 10040747 Respiratory, thoracic and
Mild but more than usual N/A 10041349 Nervous system disorders
Moderate sedation; limiti N/A 10041349 Nervous system disorders
Obtundation or stupor N/A 10041349 Nervous system disorders
Mild or slight increase in N/A 10041416 Nervous system disorders
Moderate increase in musc N/A 10041416 Nervous system disorders
Severe increase in muscle N/A 10041416 Nervous system disorders
Life-threatening; unable t Clarification 10041416 Nervous system disorders
Asymptomatic or mild neuro Clarification 10042244 Nervous system disorders
Moderate neurologic defic Clarification 10042244 Nervous system disorders
Severe neurologic deficit Clarification 10042244 Nervous system disorders
Fainting; orthostatic colla N/A 10042772 Nervous system disorders
Mild neurologic deficit wi N/A 10044391 Nervous system disorders
Moderate neurologic defic N/A 10044391 Nervous system disorders
A disorder characterized by Clarification 10060890 Nervous system disorders
Present N/A 10047166 Nervous system disorders
Fetal loss at any gestation Deletion 10072314 Pregnancy, puerperium and
A disorder characterized b Deletion 10072314 Pregnancy, puerperium and
<10% percentile of weight N/A 10054746 Pregnancy, puerperium and
<5% percentile of weight f N/A 10054746 Pregnancy, puerperium and
<1% percentile of weight f N/A 10054746 Pregnancy, puerperium and
A disorder characterized by N/A 10054746 Pregnancy, puerperium and
Asymptomatic or mild sympt N/A 10036585 Pregnancy, puerperium and
Moderate, local or noninva Clarification 10036585 Pregnancy, puerperium and
Severe or medically signifi Clarification 10036585 Pregnancy, puerperium and
Life-threatening consequen N/A 10036585 Pregnancy, puerperium and
Death N/A 10036585 Pregnancy, puerperium and
Delivery of a liveborn infa N/A 10036595 Pregnancy, puerperium and
A disorder characterized by N/A 10036595 Pregnancy, puerperium and
Unintended pregnancy Deletion 10036585 Pregnancy, puerperium and
A disorder characterized Deletion 10036585 Pregnancy, puerperium and
Mild mood alteration N/A 10001497 Psychiatric disorders
Moderate mood alteratio N/A 10001497 Psychiatric disorders
Severe agitation; hospitali N/A 10001497 Psychiatric disorders
Life-threatening consequen N/A 10001497 Psychiatric disorders
A disorder characterized by N/A 10001497 Psychiatric disorders
Death Deletion 10037175 Psychiatric disorders
Inability to achieve orgasm N/A 10002652 Psychiatric disorders
Inability to achieve orgasm N/A 10002652 Psychiatric disorders
A disorder characterized b N/A 10002652 Psychiatric disorders
Mild symptoms; interventi N/A 10002855 Psychiatric disorders
Moderate symptoms; limit N/A 10002855 Psychiatric disorders
Severe symptoms; limiting Clarification 10002855 Psychiatric disorders
Life-threatening; hospitali Clarification 10002855 Psychiatric disorders
Mild disorientation N/A 10010300 Psychiatric disorders
Moderate disorientation; l N/A 10010300 Psychiatric disorders
Severe disorientation; limi N/A 10010300 Psychiatric disorders
Delay in achieving orgasm N/A 10057066 Psychiatric disorders
Delay in achieving orgasm N/A 10057066 Psychiatric disorders
Mild acute confusional sta N/A 10012218 Psychiatric disorders
Moderate and acute confus N/A 10012218 Psychiatric disorders
Severe and acute confusiona Clarification 10012218 Psychiatric disorders
Life-threatening consequenc Clarification 10012218 Psychiatric disorders
Death N/A 10012218 Psychiatric disorders
Moderate delusional sym N/A 10012260 Psychiatric disorders
Severe delusional symptoms Clarification 10012260 Psychiatric disorders
Mild depressive symptom N/A 10012378 Psychiatric disorders
Moderate depressive symp N/A 10012378 Psychiatric disorders
Severe depressive symptoms N/A 10012378 Psychiatric disorders
Mild mood elevation N/A 10015533 Psychiatric disorders
Moderate mood elevation N/A 10015533 Psychiatric disorders
Severe mood elevation (e. N/A 10015533 Psychiatric disorders
Mild hallucinations (e.g., N/A 10019077 Psychiatric disorders
Moderate hallucinations N/A 10019077 Psychiatric disorders
Severe hallucinations; hosp N/A 10019077 Psychiatric disorders
Mild difficulty falling asl N/A 10022437 Psychiatric disorders
Moderate difficulty falling N/A 10022437 Psychiatric disorders
Severe difficulty in falling N/A 10022437 Psychiatric disorders
Decrease in sexual interest N/A 10024419 Psychiatric disorders
Decrease in sexual interest N/A 10024419 Psychiatric disorders
Mild increase in sexual int Clarification 10024421 Psychiatric disorders
Moderate increase in sexua Deletion 10024421 Psychiatric disorders
Severe increase in sexual Deletion 10024421 Psychiatric disorders
Mild manic symptoms (e.g. N/A 10026749 Psychiatric disorders
Moderate manic symptoms (e N/A 10026749 Psychiatric disorders
Severe manic symptoms (e.g Clarification 10026749 Psychiatric disorders
Mild personality change N/A 10034719 Psychiatric disorders
Moderate personality cha N/A 10034719 Psychiatric disorders
Severe personality change; N/A 10034719 Psychiatric disorders
Asymptomatic or mild sympt N/A 10037175 Psychiatric disorders
Moderate; minimal, local o N/A 10037175 Psychiatric disorders
Severe or medically signifi Clarification 10037175 Psychiatric disorders
Mild psychotic symptoms N/A 10037234 Psychiatric disorders
Moderate psychotic symptom N/A 10037234 Psychiatric disorders
Severe psychotic symptoms Clarification 10037234 Psychiatric disorders
Mild symptoms; interventi N/A 10038743 Psychiatric disorders
Moderate symptoms; limit N/A 10038743 Psychiatric disorders
Severe symptoms; limiting N/A 10038743 Psychiatric disorders
Increased thoughts of deat N/A 10042458 Psychiatric disorders
Suicidal ideation with no s N/A 10042458 Psychiatric disorders
Specific plan to commit su N/A 10042458 Psychiatric disorders
Specific plan to commit sui N/A 10042458 Psychiatric disorders
Suicide attempt or gesture Clarification 10042464 Psychiatric disorders
Suicide attempt with inten N/A 10042464 Psychiatric disorders
Creatinine level increase o Deletion 10011368 Investigations
Creatinine 2 - 3 x above ba Deletion 10011368 Investigations
Creatinine >3 x baseline o Clarification 10069339 Renal and urinary disorder
Life-threatening consequen N/A 10069339 Renal and urinary disorder
Death N/A 10069339 Renal and urinary disorder
A disorder characterized by Clarification 10069339 Renal and urinary disorder
Extraperitoneal perforatio Clarification 10063575 Renal and urinary disorder
Intraperitoneal perforation Clarification 10063575 Renal and urinary disorder
A disorder characterized b N/A 10063575 Renal and urinary disorder
Intervention not indicated N/A 10048994 Renal and urinary disorder
Antispasmodics indicated N/A 10048994 Renal and urinary disorder
Hospitalization indicated N/A 10048994 Renal and urinary disorder
eGFR (estimated Glomerular N/A 10064848 Renal and urinary disorder
eGFR or CrCl 59 - 30 ml/m N/A 10064848 Renal and urinary disorder
eGFR or CrCl 29 - 15 ml/m N/A 10064848 Renal and urinary disorder
eGFR or CrCl <15 ml/min/1. N/A 10064848 Renal and urinary disorder
A disorder characterized by N/A 10064848 Renal and urinary disorder
Microscopic hematuria; min N/A 10063057 Renal and urinary disorder
Moderate hematuria; modera N/A 10063057 Renal and urinary disorder
Gross hematuria; transfusi Clarification 10063057 Renal and urinary disorder
Life-threatening consequen Clarification 10063057 Renal and urinary disorder
Asymptomatic; clinical or N/A 10019450 Renal and urinary disorder
Symptomatic; urinary cathe N/A 10019450 Renal and urinary disorder
Gross hematuria; transfusio Clarification 10019450 Renal and urinary disorder
Asymptomatic; clinical or N/A 10019489 Renal and urinary disorder
1+ proteinuria; urinary pro Clarification 10037032 Renal and urinary disorder
Adults: 2+ proteinuria; urin Clarification 10037032 Renal and urinary disorder
Pediatric: urine P/C >1.9 Clarification 10037032 Renal and urinary disorder
Asymptomatic or mild sympt N/A 10038359 Renal and urinary disorder
Moderate, local or noninva Clarification 10038359 Renal and urinary disorder
Severe or medically signifi Clarification 10038359 Renal and urinary disorder
Asymptomatic or mild symp N/A 10038385 Renal and urinary disorder
Symptomatic; oral antiemet N/A 10038385 Renal and urinary disorder
Hospitalization indicated; Clarification 10038385 Renal and urinary disorder
A disorder characterized by Clarification 10038385 Renal and urinary disorder
Mild pain not interfering N/A 10038419 Renal and urinary disorder
Moderate pain; limiting in N/A 10038419 Renal and urinary disorder
Hospitalization indicated; N/A 10038419 Renal and urinary disorder
A disorder characterized b Clarification 10038419 Renal and urinary disorder
Mild symptoms; interventi N/A 10038463 Renal and urinary disorder
Analgesics and hematocrit N/A 10038463 Renal and urinary disorder
Transfusion, radiation, or Clarification 10038463 Renal and urinary disorder
Noninvasive intervention i Clarification 10065368 Renal and urinary disorder
Limiting self care ADL; el Clarification 10065368 Renal and urinary disorder
A disorder characterized N/A 10065368 Renal and urinary disorder
Present N/A 10046539 Renal and urinary disorder
Limiting instrumental ADL N/A 10046539 Renal and urinary disorder
Occasional (e.g., with coug N/A 10046543 Renal and urinary disorder
Spontaneous; pads indicat N/A 10046543 Renal and urinary disorder
Intervention indicated (e.g N/A 10046543 Renal and urinary disorder
Urinary, suprapubic or int N/A 10046555 Renal and urinary disorder
Placement of urinary, supr N/A 10046555 Renal and urinary disorder
Elective operative or radio Clarification 10046555 Renal and urinary disorder
Asymptomatic; clinical or Clarification 10061574 Renal and urinary disorder
Symptomatic but no hydrone Clarification 10061574 Renal and urinary disorder
Symptomatic and altered or Clarification 10061574 Renal and urinary disorder
Mild pain N/A 10062225 Renal and urinary disorder
Moderate pain; limiting i N/A 10062225 Renal and urinary disorder
Severe pain; limiting self N/A 10062225 Renal and urinary disorder
Limiting instrumental ADL N/A 10046593 Renal and urinary disorder
Absence of sperm in ejacu Deletion 10003883 Reproductive system and b
A disorder characterized b N/A 10003883 Reproductive system and b
Minimal asymmetry; minim N/A 10006179 Reproductive system and b
Moderate asymmetry; mod N/A 10006179 Reproductive system and b
Asymmetry >1/3 of breast N/A 10006179 Reproductive system and b
A disorder characterized N/A 10006179 Reproductive system and b
Mild pain N/A 10006298 Reproductive system and b
Moderate pain; limiting i N/A 10006298 Reproductive system and b
Severe pain; limiting self N/A 10006298 Reproductive system and b
A disorder characterized b Clarification 10006298 Reproductive system and b
Mild symptoms; interventi N/A 10013934 Reproductive system and b
Moderate symptoms; limit N/A 10013934 Reproductive system and b
Severe symptoms; limiting N/A 10013934 Reproductive system and b
Mild discomfort or pain as N/A 10013941 Reproductive system and b
Moderate discomfort or pai N/A 10013941 Reproductive system and b
Severe discomfort or pain N/A 10013941 Reproductive system and b
A disorder characterized by N/A 10013941 Reproductive system and b
Diminished ejaculation N/A 10014326 Reproductive system and b
Anejaculation or retrograd N/A 10014326 Reproductive system and b
Decrease in erectile functi N/A 10061461 Reproductive system and b
Decrease in erectile functi N/A 10061461 Reproductive system and b
Decrease in erectile funct N/A 10061461 Reproductive system and b
Diagnostic observations on Clarification 10065789 Reproductive system and b
Mild symptoms; elective i Clarification 10065789 Reproductive system and b
Severe symptoms; elective Clarification 10065789 Reproductive system and b
Asymptomatic clinical or d Deletion 10038604 Reproductive system and b
Symptomatic and intervent Deletion 10038604 Reproductive system and b
Severe symptoms; elective Deletion 10038604 Reproductive system and b
Life-threatening consequen Deletion 10038604 Reproductive system and b
Death Deletion 10038604 Reproductive system and b
A disorder characterized b Deletion 10038604 Reproductive system and b
Symptomatic and intervent Deletion 10038604 Reproductive system and b
Severe symptoms; elective Deletion 10038604 Reproductive system and b
A disorder characterized Deletion 10038604 Reproductive system and b
Mild symptoms; interventi N/A 10054382 Reproductive system and b
Moderate symptoms; medic N/A 10054382 Reproductive system and b
Mild swelling or obscurati N/A 10018146 Reproductive system and b
Readily apparent obscurati N/A 10018146 Reproductive system and b
Lymphorrhea; gross deviat N/A 10018146 Reproductive system and b
Asymptomatic breast enl Clarification 10018801 Reproductive system and b
Symptomatic (e.g., pain or N/A 10018801 Reproductive system and b
Severe symptoms; elective N/A 10018801 Reproductive system and b
Minimal bleeding identifie N/A 10060602 Reproductive system and b
Moderate bleeding; medica N/A 10060602 Reproductive system and b
Severe bleeding; transfusi Clarification 10060602 Reproductive system and b
Life-threatening consequen N/A 10060602 Reproductive system and b
Death N/A 10060602 Reproductive system and b
Intermittent menses with Clarification 10022992 Reproductive system and b
Intermittent menses with Clarification 10022992 Reproductive system and b
Persistent amenorrhea fo Deletion 10001927 Reproductive system and b
Mild changes in lactation, N/A 10061261 Reproductive system and b
Changes in lactation, signi N/A 10061261 Reproductive system and b
Mild; iron supplements in N/A 10027313 Reproductive system and b
Moderate symptoms; medica N/A 10027313 Reproductive system and b
Severe; transfusion indicat Clarification 10027313 Reproductive system and b
Asymptomatic; asymmetry w N/A 10065823 Reproductive system and b
Symptomatic; asymmetry of N/A 10065823 Reproductive system and b
Sperm concentration >48 m Clarification 10030300 Reproductive system and b
Sperm concentration 13 - 4 Deletion 10030300 Reproductive system and b
Sperm concentration <13 m Deletion 10030300 Reproductive system and b
Minimal bleeding identifie Clarification 10065763 Reproductive system and b
Moderate bleeding; medica Clarification 10065763 Reproductive system and b
Life-threatening consequen Clarification 10065763 Reproductive system and b
Asymptomatic clinical or d N/A 10033279 Reproductive system and b
Symptomatic and intervent N/A 10033279 Reproductive system and b
Transfusion, radiologic, en Clarification 10033279 Reproductive system and b
Mild pain Deletion 10033314 Reproductive system and b
Moderate pain; limiting i Clarification 10033314 Reproductive system and b
Severe pain; limiting self Deletion 10033314 Reproductive system and b
Asymptomatic; clinical or N/A 10064026 Reproductive system and b
Symptomatic, not interferi N/A 10064026 Reproductive system and b
Severe symptoms; limiting N/A 10064026 Reproductive system and b
Present Deletion 10036601 Reproductive system and b
Asymptomatic or mild sympt N/A 10038604 Reproductive system and b
Moderate; minimal, local o N/A 10038604 Reproductive system and b
Severe or medically signifi Clarification 10038604 Reproductive system and b
Asymptomatic; clinical or N/A 10043306 Reproductive system and b
Symptomatic but not interfe Clarification 10043306 Reproductive system and b
Severe symptoms; interferin Clarification 10043306 Reproductive system and b
Asymptomatic clinical or d Clarification 10065811 Reproductive system and b
Symptomatic and intervent Clarification 10065811 Reproductive system and b
Mild vaginal discharge (gre N/A 10046901 Reproductive system and b
Moderate to heavy vaginal N/A 10046901 Reproductive system and b
Mild vaginal dryness not i N/A 10046904 Reproductive system and b
Moderate vaginal dryness i N/A 10046904 Reproductive system and b
Severe vaginal dryness res N/A 10046904 Reproductive system and b
Asymptomatic clinical or d Clarification 10065813 Reproductive system and b
Mild discomfort or pain, N/A 10046916 Reproductive system and b
Moderate discomfort or pa N/A 10046916 Reproductive system and b
Severe discomfort or pain, N/A 10046916 Reproductive system and b
Widespread areas of mucosa Clarification 10046916 Reproductive system and b
Asymptomatic; mild vagina N/A 10053496 Reproductive system and b
Vaginal narrowing and/or s N/A 10053496 Reproductive system and b
Vaginal narrowing and/or s N/A 10053496 Reproductive system and b
Mild discomfort or pain as Deletion 10038604 Reproductive system and b
Moderate discomfort or pai Deletion 10038604 Reproductive system and b
Severe discomfort or pain Deletion 10038604 Reproductive system and b
A disorder characterized by Deletion 10038604 Reproductive system and b
Present with radiologic fin N/A 10001409 Respiratory, thoracic and
Life-threatening respirat N/A 10001409 Respiratory, thoracic and
Death N/A 10001409 Respiratory, thoracic and
A disorder characterized b N/A 10001409 Respiratory, thoracic and
Mild symptoms; interventi N/A 10001723 Respiratory, thoracic and
Moderate symptoms; medic N/A 10001723 Respiratory, thoracic and
A disorder characterized N/A 10001723 Respiratory, thoracic and
Present; medical intervent N/A 10002972 Respiratory, thoracic and
Asymptomatic; clinical or N/A 10003504 Respiratory, thoracic and
Altered eating habits; cou N/A 10003504 Respiratory, thoracic and
Dyspnea and pneumonia sym N/A 10003504 Respiratory, thoracic and
A disorder characterized by N/A 10003504 Respiratory, thoracic and
Symptomatic (e.g., dyspnea N/A 10003598 Respiratory, thoracic and
Oxygen indicated; hospitali Clarification 10003598 Respiratory, thoracic and
Asymptomatic; clinical or Clarification 10006437 Respiratory, thoracic and
Symptomatic; tube thorac Clarification 10006437 Respiratory, thoracic and
Severe symptoms; limiting Clarification 10006437 Respiratory, thoracic and
Life-threatening consequen Clarification 10006437 Respiratory, thoracic and
Symptomatic (e.g., mild wh N/A 10006440 Respiratory, thoracic and
Shortness of breath with st N/A 10006440 Respiratory, thoracic and
Symptomatic (e.g., rhonchi N/A 10063524 Respiratory, thoracic and
Shortness of breath with st N/A 10063524 Respiratory, thoracic and
Symptomatic; tube thoraco Clarification 10053481 Respiratory, thoracic and
Moderate symptoms; medic Clarification 10065746 Respiratory, thoracic and
Transfusion, radiologic, en Clarification 10065746 Respiratory, thoracic and
Life-threatening respirat Clarification 10065746 Respiratory, thoracic and
Symptomatic; medical inter N/A 10006482 Respiratory, thoracic and
Limiting self care ADL; ox Clarification 10006482 Respiratory, thoracic and
Symptomatic; thoracentesi Clarification 10051228 Respiratory, thoracic and
Severe symptoms; elective N/A 10051228 Respiratory, thoracic and
Mild symptoms; nonprescri N/A 10011224 Respiratory, thoracic and
Moderate symptoms, medica N/A 10011224 Respiratory, thoracic and
Severe symptoms; limiting N/A 10011224 Respiratory, thoracic and
Shortness of breath with N/A 10013963 Respiratory, thoracic and
Shortness of breath with m N/A 10013963 Respiratory, thoracic and
Shortness of breath at rest N/A 10013963 Respiratory, thoracic and
Life-threatening consequen N/A 10013963 Respiratory, thoracic and
Moderate symptoms; medical N/A 10015090 Respiratory, thoracic and
Moderate symptoms; medica N/A 10020039 Respiratory, thoracic and
Severe symptoms; interferi N/A 10020039 Respiratory, thoracic and
Mild or intermittent voice N/A 10020201 Respiratory, thoracic and
Moderate or persistent vo N/A 10020201 Respiratory, thoracic and
Severe voice changes incl N/A 10020201 Respiratory, thoracic and
Decreased oxygen saturati N/A 10021143 Respiratory, thoracic and
Decreased oxygen saturati N/A 10021143 Respiratory, thoracic and
Life-threatening airway co N/A 10021143 Respiratory, thoracic and
Symptomatic; medical inte N/A 10023838 Respiratory, thoracic and
Stridor; respiratory distres N/A 10023838 Respiratory, thoracic and
Mild cough or trace hemopt N/A 10065759 Respiratory, thoracic and
Life-threatening airway co Clarification 10065759 Respiratory, thoracic and
Mild sore throat; raspy vo N/A 10065735 Respiratory, thoracic and
Moderate sore throat; anal N/A 10065735 Respiratory, thoracic and
Severe throat pain; endosc N/A 10065735 Respiratory, thoracic and
Endoscopic findings only; N/A 10065880 Respiratory, thoracic and
Moderate discomfort; alte Clarification 10065880 Respiratory, thoracic and
Severe pain; severely alte N/A 10065880 Respiratory, thoracic and
A disorder characterized Clarification 10065880 Respiratory, thoracic and
Symptomatic (e.g., noisy a Clarification 10059639 Respiratory, thoracic and
Limiting self care ADL; stri N/A 10059639 Respiratory, thoracic and
Mild symptoms; no anxiety N/A 10062667 Respiratory, thoracic and
Moderate symptoms; mild an Clarification 10062667 Respiratory, thoracic and
Severe symptoms; dyspnea a N/A 10062667 Respiratory, thoracic and
Life-threatening conseque N/A 10062667 Respiratory, thoracic and
Transient episode; interve N/A 10023891 Respiratory, thoracic and
Recurrent episodes; noninv N/A 10023891 Respiratory, thoracic and
Persistent or severe episod N/A 10023891 Respiratory, thoracic and
Radiologic evidence only; Clarification 10056356 Respiratory, thoracic and
Associated with bloody nas N/A 10028735 Respiratory, thoracic and
Moderate pain and analgesi Clarification 10065881 Respiratory, thoracic and
Severe pain; unable to adeq N/A 10065881 Respiratory, thoracic and
Inability to aliment adequa Clarification 10065706 Respiratory, thoracic and
Mild pain N/A 10034844 Respiratory, thoracic and
Moderate pain; limiting i N/A 10034844 Respiratory, thoracic and
Severe pain; limiting self N/A 10034844 Respiratory, thoracic and
Symptomatic; intervention i Clarification 10035598 Respiratory, thoracic and
Symptomatic with respirato Clarification 10035598 Respiratory, thoracic and
Asymptomatic; mild hemor N/A 10055319 Respiratory, thoracic and
Symptomatic or associated N/A 10055319 Respiratory, thoracic and
>1000 ml of blood evacuate Clarification 10055319 Respiratory, thoracic and
Severe pain; limiting self N/A 10035623 Respiratory, thoracic and
A disorder characterized b Clarification 10035623 Respiratory, thoracic and
Symptomatic; medical inter N/A 10035742 Respiratory, thoracic and
Severe symptoms; limiting N/A 10035742 Respiratory, thoracic and
Life-threatening respirato N/A 10035742 Respiratory, thoracic and
Symptomatic; intervention Clarification 10035759 Respiratory, thoracic and
Sclerosis and/or operative N/A 10035759 Respiratory, thoracic and
Occasional/minimal produ N/A 10036790 Respiratory, thoracic and
Moderate sputum productio N/A 10036790 Respiratory, thoracic and
Persistent or copious prod N/A 10036790 Respiratory, thoracic and
Radiologic findings only; N/A 10037375 Respiratory, thoracic and
Moderate dyspnea on exert N/A 10037375 Respiratory, thoracic and
Severe dyspnea or dyspnea N/A 10037375 Respiratory, thoracic and
Life-threatening respirato N/A 10037375 Respiratory, thoracic and
Mild hypoxemia; radiologi Clarification 10037383 Respiratory, thoracic and
Moderate hypoxemia; evide Clarification 10037383 Respiratory, thoracic and
Severe hypoxemia; evidence Clarification 10037383 Respiratory, thoracic and
Life-threatening conseque N/A 10037383 Respiratory, thoracic and
Limiting self care ADL; en Clarification 10065873 Respiratory, thoracic and
Minimal dyspnea; findings N/A 10037400 Respiratory, thoracic and
Moderate dyspnea, cough; N/A 10037400 Respiratory, thoracic and
Severe symptoms, associat Clarification 10037400 Respiratory, thoracic and
Asymptomatic or mild sympt N/A 10038738 Respiratory, thoracic and
Moderate; minimal, local o N/A 10038738 Respiratory, thoracic and
Severe or medically signifi Clarification 10038738 Respiratory, thoracic and
Fluid retention; <3 kg of w N/A 10038921 Respiratory, thoracic and
Moderate signs or symptom N/A 10038921 Respiratory, thoracic and
Severe symptoms; hospital N/A 10038921 Respiratory, thoracic and
Asymptomatic mucosal crus N/A 10062244 Respiratory, thoracic and
Symptomatic stenosis or e N/A 10062244 Respiratory, thoracic and
Stenosis with significant n N/A 10062244 Respiratory, thoracic and
Necrosis of soft tissue or N/A 10062244 Respiratory, thoracic and
Snoring and nocturnal sle N/A 10040975 Respiratory, thoracic and
Moderate apnea and oxygen N/A 10040975 Respiratory, thoracic and
Oxygen desaturation; assoc Clarification 10040975 Respiratory, thoracic and
Cardiovascular or neurops N/A 10040975 Respiratory, thoracic and
Severe pain; limiting self c N/A 10041367 Respiratory, thoracic and
Respiratory distress limiti N/A 10042241 Respiratory, thoracic and
Severe pain; hemorrhage or N/A 10065900 Respiratory, thoracic and
Stridor or respiratory distr Clarification 10050816 Respiratory, thoracic and
Mild or intermittent chan N/A 10047681 Respiratory, thoracic and
Moderate or persistent ch N/A 10047681 Respiratory, thoracic and
Severe voice changes inclu N/A 10047681 Respiratory, thoracic and
Detectable airway noise N/A 10047924 Respiratory, thoracic and
Severe respiratory symptom N/A 10047924 Respiratory, thoracic and
Hair loss of <50% of normal N/A 10001760 Skin and subcutaneous tis
Hair loss of >=50% normal f N/A 10001760 Skin and subcutaneous tis
A disorder characterized b N/A 10001760 Skin and subcutaneous tis
Mild odor; physician interv N/A 10005901 Skin and subcutaneous tis
Pronounced odor; psychoso N/A 10005901 Skin and subcutaneous tis
Asymptomatic; blisters co N/A 10006556 Skin and subcutaneous tis
Blisters covering 10 - 30% N/A 10006556 Skin and subcutaneous tis
Blisters covering >30% BSA; N/A 10006556 Skin and subcutaneous tis
Blisters covering >30% BSA; N/A 10006556 Skin and subcutaneous tis
Death N/A 10006556 Skin and subcutaneous tis
A disorder characterized by N/A 10006556 Skin and subcutaneous tis
Covering <10% BSA and no N/A 10013786 Skin and subcutaneous tis
Covering 10 - 30% BSA and N/A 10013786 Skin and subcutaneous tis
Covering >30% BSA and asso N/A 10013786 Skin and subcutaneous tis
Target lesions covering < N/A 10015218 Skin and subcutaneous tis
Target lesions covering 10 N/A 10015218 Skin and subcutaneous tis
Target lesions covering >3 N/A 10015218 Skin and subcutaneous tis
Target lesions covering >3 N/A 10015218 Skin and subcutaneous tis
Erythema covering >90% BS N/A 10015277 Skin and subcutaneous tis
Erythema covering >90% BSA N/A 10015277 Skin and subcutaneous tis
Covering <10% BSA and a N/A 10016241 Skin and subcutaneous tis
Covering >30% BSA; associ N/A 10016241 Skin and subcutaneous tis
In women, increase in lengt N/A 10020112 Skin and subcutaneous tis
In women, increase in leng N/A 10020112 Skin and subcutaneous tis
A disorder characterized N/A 10020112 Skin and subcutaneous tis
Limited to one site (palms, N/A 10020642 Skin and subcutaneous tis
Involving >1 site; patient N/A 10020642 Skin and subcutaneous tis
Generalized involving site Clarification 10020642 Skin and subcutaneous tis
A disorder characterized b Clarification 10020642 Skin and subcutaneous tis
Increase in length, thickn N/A 10020864 Skin and subcutaneous tis
Increase in length, thickn N/A 10020864 Skin and subcutaneous tis
Symptomatic; limiting ins N/A 10021013 Skin and subcutaneous tis
Increase in body temperatu N/A 10021013 Skin and subcutaneous tis
Heat stroke N/A 10021013 Skin and subcutaneous tis
A disorder characterized N/A 10021013 Skin and subcutaneous tis
Asymptomatic and coveri N/A 10062315 Skin and subcutaneous tis
Covering >30% BSA and asso N/A 10062315 Skin and subcutaneous tis
Asymptomatic; clinical or Clarification 10028691 Skin and subcutaneous tis
Asymptomatic separation of N/A 10049281 Skin and subcutaneous tis
Symptomatic separation of t N/A 10049281 Skin and subcutaneous tis
Asymptomatic; clinical or N/A 10062283 Skin and subcutaneous tis
Mild pain N/A 10033474 Skin and subcutaneous tis
Moderate pain; limiting i N/A 10033474 Skin and subcutaneous tis
Severe pain; limiting self N/A 10033474 Skin and subcutaneous tis
Minimal skin changes or de N/A 10054524 Skin and subcutaneous tis
Skin changes (e.g., peeling Clarification 10054524 Skin and subcutaneous tis
Severe skin changes (e.g., Clarification 10054524 Skin and subcutaneous tis
A disorder characterized by Clarification 10054524 Skin and subcutaneous tis
Soft or non-pitting Primary SOC change 10054541 Eye disorders
Indurated or pitting edemaPrimary SOC change 10054541 Eye disorders
Edema associated with visuPrimary SOC change 10054541 Eye disorders
A disorder characterized b Primary SOC change 10054541 Eye disorders
Painless erythema and er N/A 10034966 Skin and subcutaneous tis
Tender erythema covering N/A 10034966 Skin and subcutaneous tis
Life-threatening consequen N/A 10034966 Skin and subcutaneous tis
Mild or localized; topical N/A 10037087 Skin and subcutaneous tis
Intense or widespread; inte Clarification 10037087 Skin and subcutaneous tis
Intense or widespread; con Clarification 10037087 Skin and subcutaneous tis
Combined area of lesions N/A 10037549 Skin and subcutaneous tis
Papules and/or pustules c N/A 10037847 Skin and subcutaneous tis
Papules and/or pustules c Clarification 10037847 Skin and subcutaneous tis
Papules and/or pustules co Clarification 10037847 Skin and subcutaneous tis
Papules and/or pustules co Clarification 10037847 Skin and subcutaneous tis
Macules/papules covering N/A 10037868 Skin and subcutaneous tis
Macules/papules covering 1 Clarification 10037868 Skin and subcutaneous tis
Macules/papules covering Clarification 10037868 Skin and subcutaneous tis
Mild pain N/A 10049120 Skin and subcutaneous tis
Moderate pain; limiting i N/A 10049120 Skin and subcutaneous tis
Severe pain; limiting self N/A 10049120 Skin and subcutaneous tis
Asymptomatic or mild sympt N/A 10040785 Skin and subcutaneous tis
Moderate; minimal, local o N/A 10040785 Skin and subcutaneous tis
Severe or medically signifi Clarification 10040785 Skin and subcutaneous tis
Life-threatening consequen N/A 10040785 Skin and subcutaneous tis
Covering <10% BSA; associa N/A 10040799 Skin and subcutaneous tis
Covering 10 - 30% BSA; ass N/A 10040799 Skin and subcutaneous tis
Covering >30% BSA; associ N/A 10040799 Skin and subcutaneous tis
Hyperpigmentation coveri N/A 10040865 Skin and subcutaneous tis
Hyperpigmentation coveri N/A 10040865 Skin and subcutaneous tis
Hypopigmentation or depi N/A 10040868 Skin and subcutaneous tis
Hypopigmentation or depi N/A 10040868 Skin and subcutaneous tis
Mild induration, able to mo N/A 10051837 Skin and subcutaneous tis
Moderate induration, able t N/A 10051837 Skin and subcutaneous tis
Severe induration, unable t Clarification 10051837 Skin and subcutaneous tis
Generalized; associated w N/A 10051837 Skin and subcutaneous tis
Combined area of ulcers < N/A 10040947 Skin and subcutaneous tis
Combined area of ulcers 1 - N/A 10040947 Skin and subcutaneous tis
Combined area of ulcers >2 N/A 10040947 Skin and subcutaneous tis
Any size ulcer with extensi N/A 10040947 Skin and subcutaneous tis
Skin sloughing covering Clarification 10042033 Skin and subcutaneous tis
Skin sloughing covering 1 N/A 10042033 Skin and subcutaneous tis
Telangiectasias covering N/A 10043189 Skin and subcutaneous tis
Telangiectasias covering Clarification 10043189 Skin and subcutaneous tis
Skin sloughing covering > N/A 10044223 Skin and subcutaneous tis
Urticarial lesions covering N/A 10046735 Skin and subcutaneous tis
Urticarial lesions covering N/A 10046735 Skin and subcutaneous tis
Urticarial lesions coverin N/A 10046735 Skin and subcutaneous tis
Menopause occurring at ag Deletion 10036601 Reproductive system and b
Menopause occurring at ag Deletion 10036601 Reproductive system and b
Menopause occurring befor Deletion 10036601 Reproductive system and b
A disorder characterized Deletion 10036601 Reproductive system and b
Asymptomatic or mild sympt N/A 10041244 Social circumstances
Moderate; minimal, local o N/A 10041244 Social circumstances
Severe or medically signifi Clarification 10041244 Social circumstances
Life-threatening consequen N/A 10041244 Social circumstances
Death N/A 10041244 Social circumstances
Asymptomatic or mild sympt N/A 10042613 Surgical and medical proc
Moderate; minimal, local o N/A 10042613 Surgical and medical proc
Severe or medically signifi Clarification 10042613 Surgical and medical proc
Life-threatening consequen N/A 10042613 Surgical and medical proc
Death N/A 10042613 Surgical and medical proc
Symptomatic; medical inte N/A 10007196 Vascular disorders
Severe symptoms; interven N/A 10007196 Vascular disorders
Life-threatening consequen N/A 10007196 Vascular disorders
Death N/A 10007196 Vascular disorders
A disorder characterized b N/A 10007196 Vascular disorders
Asymptomatic; clinical or Clarification 10016825 Vascular disorders
Moderate symptoms; medica Clarification 10016825 Vascular disorders
Symptomatic, associated wi N/A 10016825 Vascular disorders
A disorder characterized b Clarification 10016825 Vascular disorders
Mild symptoms; interventi N/A 10019428 Vascular disorders
Minimally invasive evacuat N/A 10019428 Vascular disorders
Transfusion, radiologic, en Clarification 10019428 Vascular disorders
A disorder characterized by N/A 10019428 Vascular disorders
Mild symptoms; interventi N/A 10020407 Vascular disorders
Moderate symptoms; limit N/A 10020407 Vascular disorders
Severe symptoms; limiting N/A 10020407 Vascular disorders
A disorder characterized N/A 10020407 Vascular disorders
Prehypertension (systolic Clarification 10020772 Vascular disorders
Pediatric: recurrent or persistent
Clarification
(>=24 hrs) BP >ULN;
10020772
monotherapy indicated
Vascular disorders
Pediatric: Same as adult Clarification 10020772 Vascular disorders
Pediatric: Same as adult Clarification 10020772 Vascular disorders
A disorder characterized b Clarification 10020772 Vascular disorders
Asymptomatic, interventio N/A 10021097 Vascular disorders
Non-urgent medical interv N/A 10021097 Vascular disorders
Medical intervention or ho Clarification 10021097 Vascular disorders
Life-threatening and urgen Clarification 10021097 Vascular disorders
Severe symptoms; radiologi Clarification 10065773 Vascular disorders
Trace thickening or faint d N/A 10025233 Vascular disorders
Marked discoloration; leat N/A 10025233 Vascular disorders
Severe symptoms; limiting N/A 10025233 Vascular disorders
Asymptomatic; clinical or N/A 10048642 Vascular disorders
Severe symptoms; radiologi Clarification 10048642 Vascular disorders
Brief (<24 hrs) episode o Clarification 10034578 Vascular disorders
Recurring or prolonged (>= Clarification 10034578 Vascular disorders
Life-threatening conseque N/A 10034578 Vascular disorders
Present N/A 10034879 Vascular disorders
Present N/A 10042554 Vascular disorders
Asymptomatic; incidental N/A 10042569 Vascular disorders
Symptomatic; medical inter N/A 10042569 Vascular disorders
Severe symptoms; multi-mod N/A 10042569 Vascular disorders
Venous thrombosis (e.g., s Clarification 10043565 Vascular disorders
Venous thrombosis (e.g., Clarification 10043565 Vascular disorders
Thrombosis (e.g., uncompl Clarification 10043565 Vascular disorders
Life-threatening (e.g., pu Clarification 10043565 Vascular disorders
Asymptomatic or mild sympt N/A 10047065 Vascular disorders
Moderate; minimal, local o N/A 10047065 Vascular disorders
Severe or medically signifi Clarification 10047065 Vascular disorders
Asymptomatic, interventio N/A 10047115 Vascular disorders
Moderate symptoms, medic N/A 10047115 Vascular disorders
Severe symptoms, medical i N/A 10047115 Vascular disorders
Life-threatening; evidence Clarification 10047115 Vascular disorders
Brief (<24 hrs) episode o Primary SOC change 10054692 Gastrointestinal disorders
Prolonged (>=24 hrs) or r Primary SOC change 10054692 Gastrointestinal disorders
Life-threatening conseque Primary SOC change 10054692 Gastrointestinal disorders
Death Primary SOC change 10054692 Gastrointestinal disorders
A disorder characterized b Primary SOC change 10054692 Gastrointestinal disorders
v5.0 CTCAE Term Grade/Definition v5.0 CTCAE Grade DescriptOther Specify
Anemia 1 Hemoglobin (Hgb) <LLN - 1N/A
Anemia 2 Hgb <10.0 - 8.0 g/dL; <6.2 N/A
Anemia 3 Hgb <8.0 g/dL; <4.9 mmol/L N/A
Anemia 4 Life-threatening consequen N/A
Anemia 5 Death N/A
Anemia Definition A disorder characterized bN/A
Blood and lymphatic system
1 Asymptomatic or mild sympt N/A
2 Moderate; minimal, local oN/A
3 Severe or medically signifiN/A
4 Life-threatening consequen N/A
5 Death N/A
Bone marrow hypocellular1 Mildly hypocellular or <=2N/A
Bone marrow hypocellular2 Moderately hypocellular orN/A
Bone marrow hypocellular3 Severely hypocellular or > N/A
Bone marrow hypocellular4 Aplastic persistent for lo N/A
Bone marrow hypocellular5 Death N/A
Bone marrow hypocellularDefinition A disorder characterized N/A
Disseminated intravascula2 Laboratory findings with nN/A
Disseminated intravascula3 Laboratory findings and b N/A
Disseminated intravascula4 Life-threatening consequen N/A
Disseminated intravascula5 Death N/A
Disseminated intravasculaDefinition A disorder characterized bN/A
Febrile neutropenia 3 ANC <1000/mm3 with a sing N/A
Febrile neutropenia 4 Life-threatening consequen N/A
Febrile neutropenia 5 Death N/A
Febrile neutropenia Definition A disorder characterized N/A
Hemolysis 1 Laboratory evidence of hem N/A
Hemolysis 2 Evidence of hemolysis andN/A
Hemolysis 3 Transfusion or medical inteN/A
Hemolysis 4 Life-threatening consequen N/A
Hemolysis 5 Death N/A
Hemolysis Definition A disorder characterized bN/A
Hemolytic uremic syndro 3 Laboratory findings with clN/A
Hemolytic uremic syndro 4 Life-threatening consequeN/A
Hemolytic uremic syndro 5 Death N/A
Hemolytic uremic syndro Definition A disorder characterized N/A
Leukocytosis 3 >100,000/mm3 N/A
Leukocytosis 4 Clinical manifestations of N/A
Leukocytosis 5 Death N/A
Leukocytosis Definition A disorder characterized bN/A
Lymph node pain 1 Mild pain N/A
Lymph node pain 2 Moderate pain; limiting i N/A
Lymph node pain 3 Severe pain; limiting self N/A
Lymph node pain Definition A disorder characterized bN/A
Blood and lymphatic system 1 Asymptomatic or mild sympt Spleen disorder
Blood and lymphatic system 2 Moderate; minimal, local oSpleen disorder
Blood and lymphatic system 4 Life-threatening consequen Spleen disorder
Blood and lymphatic system 5 Death Spleen disorder
Blood and lymphatic system Definition - N/A
Thrombotic thrombocytop3 Laboratory findings with clN/A
Thrombotic thrombocytop4 Life-threatening consequeN/A
Thrombotic thrombocytop5 Death N/A
Thrombotic thrombocytopDefinition A disorder characterized bN/A
Chest pain - cardiac 2 Moderate pain; pain on exN/A
Chest pain - cardiac 3 Pain at rest; limiting self N/A
Myocardial infarction 4 Life-threatening consequ N/A
Myocardial infarction 5 Death N/A
Chest pain - cardiac Definition A disorder characterized bN/A
Aortic valve disease 1 Asymptomatic valvular thicN/A
Aortic valve disease 2 Asymptomatic; moderate N/A re
Aortic valve disease 3 Symptomatic; severe regurN/A
Aortic valve disease 4 Life-threatening consequen N/A
Aortic valve disease 5 Death N/A
Aortic valve disease Definition A disorder characterized by N/A
Asystole 1 Periods of asystole; non- N/A
Asystole 4 Life-threatening consequen N/A
Asystole 5 Death N/A
Asystole Definition A disorder characterized by N/A
Atrial fibrillation 1 Asymptomatic, interventioN/A
Atrial fibrillation 2 Non-urgent medical intervN/A
Atrial fibrillation 3 Symptomatic, urgent interv N/A
Atrial fibrillation 4 Life-threatening consequences;
N/A embolus requiring urgent intervention
Atrial fibrillation 5 Death N/A
Atrial fibrillation Definition A disorder characterized bN/A
Atrial flutter 1 Asymptomatic, interventioN/A
Atrial flutter 2 Non-urgent medical intervN/A
Atrial flutter 3 Symptomatic, urgent interv N/A
Atrial flutter 4 Life-threatening consequences;
N/A embolus requiring urgent intervention
Atrial flutter 5 Death N/A
Atrial flutter Definition A disorder characterized bN/A
Atrioventricular block com2 Non-urgent intervention i N/A
Atrioventricular block com3 Symptomatic and incomplet N/A
Atrioventricular block com4 Life-threatening consequen N/A
Atrioventricular block com5 Death N/A
Atrioventricular block comDefinition A disorder characterized bN/A
Atrioventricular block firs 1 Asymptomatic, interventioN/A
Atrioventricular block firs 2 Non-urgent intervention i N/A
Atrioventricular block firs Definition A disorder characterized bN/A
Cardiac arrest 4 Life-threatening consequen N/A
Cardiac arrest 5 Death N/A
Cardiac arrest Definition A disorder characterized bN/A
Cardiac disorders - Other, 1 Asymptomatic or mild sympt N/A
Cardiac disorders - Other, 2 Moderate; minimal, local oN/A
Cardiac disorders - Other, 3 Severe or medically signifiN/A
Cardiac disorders - Other, 4 Life-threatening consequen N/A
Cardiac disorders - Other, 5 Death N/A
Chest pain - cardiac 1 Mild pain N/A
Chest pain - cardiac 2 Moderate pain; pain on exN/A
Chest pain - cardiac 3 Pain at rest; limiting self N/A
Chest pain - cardiac Definition A disorder characterized bN/A
Conduction disorder 1 Mild symptoms; interventiN/A
Conduction disorder 2 Non-urgent medical intervN/A
Conduction disorder 3 Symptomatic, urgent interN/A
Conduction disorder 4 Life-threatening consequeN/A
Conduction disorder 5 Death N/A
Conduction disorder Definition A disorder characterized by N/A
Pericarditis 3 Pericarditis with physiologN/A
Pericarditis 4 Life-threatening consequen N/A
Pericarditis 5 Death N/A
Pericarditis Definition A disorder characterized by N/A
Heart failure 1 Asymptomatic with laborato N/A
Heart failure 2 Symptoms with moderate N/A ac
Heart failure 3 Symptoms at rest or with m N/A
Heart failure 4 Life-threatening consequeN/A
Heart failure 5 Death N/A
Heart failure Definition A disorder characterized by N/A
Left ventricular systolic d 3 Symptomatic due to drop N/A in
Left ventricular systolic d 4 Refractory or poorly contro N/A
Left ventricular systolic d 5 Death N/A
Left ventricular systolic d Definition A disorder characterized bN/A
Mitral valve disease 1 Asymptomatic valvular thicN/A
Mitral valve disease 2 Asymptomatic; moderate N/A re
Mitral valve disease 3 Symptomatic; severe regurN/A
Mitral valve disease 4 Life-threatening consequen N/A
Mitral valve disease 5 Death N/A
Mitral valve disease Definition A disorder characterized by N/A
Mobitz (type) II atrioventr1 Asymptomatic, interventioN/A
Mobitz (type) II atrioventr2 Symptomatic; medical inteN/A
Mobitz (type) II atrioventr3 Symptomatic and incomplet N/A
Mobitz (type) II atrioventr4 Life-threatening consequen N/A
Mobitz (type) II atrioventr5 Death N/A
Mobitz (type) II atrioventrDefinition A disorder characterized by N/A
Mobitz type I 1 Asymptomatic, interventioN/A
Mobitz type I 2 Symptomatic; medical inteN/A
Mobitz type I 3 Symptomatic and incomplete N/A
Mobitz type I 4 Life-threatening consequen N/A
Mobitz type I 5 Death N/A
Mobitz type I Definition A disorder characterized byN/A
Myocardial infarction 2 Asymptomatic and cardiacN/A
Myocardial infarction 3 Severe symptoms; cardiacN/A
Myocardial infarction 4 Life-threatening consequ N/A
Myocardial infarction 5 Death N/A
Myocardial infarction Definition A disorder characterized bN/A
Myocarditis 2 Symptoms with moderate N/A ac
Myocarditis 3 Severe with symptoms at re N/A
Myocarditis 4 Life-threatening consequeN/A
Myocarditis 5 Death N/A
Myocarditis Definition A disorder characterized bN/A
Cardiac disorders - Other, 1 Asymptomatic or mild sympt Myocarditis
Palpitations 1 Mild symptoms; interventiN/A
Palpitations 2 Intervention indicated N/A
Palpitations Definition A disorder characterized bN/A
Paroxysmal atrial tachycar1 Asymptomatic, interventioN/A
Paroxysmal atrial tachycar2 Non-urgent medical intervN/A
Paroxysmal atrial tachycar3 Symptomatic, urgent interv N/A
Paroxysmal atrial tachycar4 Life-threatening consequen N/A
Paroxysmal atrial tachycar5 Death N/A
Paroxysmal atrial tachycarDefinition A disorder characterized bN/A
Pericardial effusion 2 Asymptomatic effusion sizN/A
Pericardial effusion 3 Effusion with physiologic N/A
Pericardial effusion 4 Life-threatening consequen N/A
Pericardial effusion 5 Death N/A
Pericardial effusion Definition A disorder characterized byN/A
Pericardial tamponade 4 Life-threatening consequen N/A
Pericardial tamponade 5 Death N/A
Pericardial tamponade Definition A disorder characterized byN/A
Pericarditis 1 Asymptomatic, ECG or physicN/A
Pericarditis 2 Symptomatic pericarditis (eN/A
Pericarditis 3 Pericarditis with physiologN/A
Pericarditis 4 Life-threatening consequen N/A
Pericarditis 5 Death N/A
Pericarditis Definition A disorder characterized byN/A
Pulmonary valve disease 1 Asymptomatic valvular thicN/A
Pulmonary valve disease 2 Asymptomatic; moderate N/A re
Pulmonary valve disease 3 Symptomatic; severe regurN/A
Pulmonary valve disease 4 Life-threatening consequen N/A
Pulmonary valve disease 5 Death N/A
Pulmonary valve disease Definition A disorder characterized bN/A
Restrictive cardiomyopath3 Symptomatic heart failureN/A
Restrictive cardiomyopath4 Refractory heart failure o N/A
Restrictive cardiomyopath5 Death N/A
Restrictive cardiomyopathDefinition A disorder characterized byN/A
Right ventricular dysfunct 1 Asymptomatic with laborato N/A
Right ventricular dysfunct 2 Symptoms with moderate N/A ac
Right ventricular dysfunct 3 Severe symptoms, associate N/A
Right ventricular dysfunct 4 Life-threatening consequencN/A
Right ventricular dysfunct 5 Death N/A
Right ventricular dysfunct Definition A disorder characterized byN/A
Sick sinus syndrome 1 Asymptomatic, interventioN/A
Sick sinus syndrome 2 Symptomatic, interventionN/A
Sick sinus syndrome 3 Symptomatic, interventionN/A
Sick sinus syndrome 4 Life-threatening consequen N/A
Sick sinus syndrome 5 Death N/A
Sick sinus syndrome Definition A disorder characterized bN/A
Sinus bradycardia 1 Asymptomatic, interventioN/A
Sinus bradycardia 2 Symptomatic, interventionN/A
Sinus bradycardia 3 Symptomatic, interventionN/A
Sinus bradycardia 4 Life-threatening consequen N/A
Sinus bradycardia 5 Death N/A
Sinus bradycardia Definition A disorder characterized bN/A
Sinus tachycardia 1 Asymptomatic, interventioN/A
Sinus tachycardia 2 Symptomatic; non-urgent N m/A
Sinus tachycardia 3 Urgent medical interventi N/A
Sinus tachycardia Definition A disorder characterized bN/A
Supraventricular tachycar 1 Asymptomatic, interventioN/A
Supraventricular tachycar 2 Non-urgent medical intervN/A
Supraventricular tachycar 3 Symptomatic, urgent interN/A
Supraventricular tachycar 4 Life-threatening consequeN/A
Supraventricular tachycar 5 Death N/A
Supraventricular tachycar Definition A disorder characterized bN/A
Tricuspid valve disease 1 Asymptomatic valvular thicN/A
Tricuspid valve disease 2 Asymptomatic; moderate N/A re
Tricuspid valve disease 3 Symptomatic; severe regurN/A
Tricuspid valve disease 4 Life-threatening consequen N/A
Tricuspid valve disease 5 Death N/A
Tricuspid valve disease Definition A disorder characterized byN/A
Ventricular arrhythmia 1 Asymptomatic, interventioN/A
Ventricular arrhythmia 2 Non-urgent medical intervN/A
Ventricular arrhythmia 3 Urgent intervention indic N/A
Ventricular arrhythmia 4 Life-threatening conseq N/A
Ventricular arrhythmia 5 Death N/A
Ventricular arrhythmia Definition A disorder characterized byN/A
Ventricular fibrillation 4 Life-threatening conseq N/A
Ventricular fibrillation 5 Death N/A
Ventricular fibrillation Definition A disorder characterized bN/A
Ventricular tachycardia 2 Non-urgent medical intervN/A
Ventricular tachycardia 3 Symptomatic, urgent interN/A
Ventricular tachycardia 4 Life-threatening conseq N/A
Ventricular tachycardia 5 Death N/A
Ventricular tachycardia Definition A disorder characterized bN/A
Cardiac disorders - Other, 1 Asymptomatic or mild sympt Wolff-Parkinson-White syndrome
Cardiac disorders - Other, 2 Moderate; minimal, local oWolff-Parkinson-White syndrome
Cardiac disorders - Other, 3 Severe or medically signifiWolff-Parkinson-White syndrome
Cardiac disorders - Other, 4 Life-threatening consequen Wolff-Parkinson-White syndrome
Cardiac disorders - Other, 5 Death Wolff-Parkinson-White syndrome
Cardiac disorders - Other, Definition - N/A
Congenital, familial and ge1 Asymptomatic or mild sympt N/A
Congenital, familial and ge2 Moderate; minimal, local oN/A
Congenital, familial and ge3 Severe or medically signifiN/A
Congenital, familial and ge4 Life-threatening consequen N/A
Congenital, familial and ge5 Death N/A
Ear and labyrinth disorders1 Asymptomatic or mild sympt N/A
Ear and labyrinth disorders2 Moderate; minimal, local oN/A
Ear and labyrinth disorders3 Severe or medically signifiN/A
Ear and labyrinth disorders4 Life-threatening consequen N/A
Ear and labyrinth disorders5 Death N/A
Ear pain 1 Mild pain N/A
Ear pain 2 Moderate pain; limiting i N/A
Ear pain 3 Severe pain; limiting self N/A
Ear pain Definition A disorder characterized bN/A
Otitis externa 1 Local intervention indicated N/A
Otitis externa 2 Oral intervention indicatedN/A
Otitis externa 3 IV antibiotic, antifungal, o N/A
Otitis externa 4 Life-threatening consequen N/A
Otitis externa 5 Death N/A
Otitis externa Definition A disorder characterized bN/A
External ear pain 1 Mild pain N/A
External ear pain 2 Moderate pain; limiting i N/A
External ear pain 3 Severe pain; limiting self N/A
External ear pain Definition A disorder characterized bN/A
Hearing impaired 1 Pediatric (on a 1, 2, 3, 4, 6,N/A
and 8 kHz audiogram): Threshold shift >20 dB hea
and 8 kHz audiogram): Threshold shift >20 dB at 4
and 8 kHz audiogram): Hearing loss sufficient to in
Hearing impaired 4 Pediatric: Audiologic indication
N/A for cochlear implant; > 40 dB HL (i.e., 45 dB H
Hearing impaired Definition A disorder characterized bN/A
Middle ear inflammation 1 Serous otitis N/A
Middle ear inflammation 2 Serous otitis, medical inte N/A
Middle ear inflammation 3 Mastoiditis; necrosis of caN/A
Middle ear inflammation 4 Life-threatening consequen N/A
Middle ear inflammation 5 Death N/A
Middle ear inflammation Definition A disorder characterized bN/A
Tinnitus 1 Mild symptoms; interventiN/A
Tinnitus 2 Moderate symptoms; limitN/A
Tinnitus 3 Severe symptoms; limitingN/A
Tinnitus Definition A disorder characterized byN/A
Vertigo 1 Mild symptoms N/A
Vertigo 2 Moderate symptoms; limitN/A
Vertigo 3 Severe symptoms; limitingN/A
Vertigo Definition A disorder characterized byN/A
Vestibular disorder 2 Symptomatic; limiting ins N/A
Vestibular disorder 3 Severe symptoms; limitingN/A
Vestibular disorder Definition A disorder characterized bN/A
Adrenal insufficiency 1 Asymptomatic; clinical or N/A
Adrenal insufficiency 2 Moderate symptoms; medic N/A
Adrenal insufficiency 3 Severe symptoms; hospitalN/A
Adrenal insufficiency 4 Life-threatening consequen N/A
Adrenal insufficiency 5 Death N/A
Adrenal insufficiency Definition A disorder characterized bN/A
Cushingoid 1 Mild symptoms; interventiN/A
Cushingoid 2 Moderate symptoms; medic N/A
Cushingoid 3 Severe symptoms, medicalN/A i
Cushingoid Definition A disorder characterized bN/A
Delayed puberty 2 No breast development byN/A
Delayed puberty 3 No breast development byN/A
Delayed puberty Definition A disorder characterized bN/A
Endocrine disorders - Othe1 Asymptomatic or mild sympt N/A
Endocrine disorders - Othe2 Moderate; minimal, local oN/A
Endocrine disorders - Othe3 Severe or medically signifiN/A
Endocrine disorders - Othe4 Life-threatening consequen N/A
Endocrine disorders - Othe5 Death N/A
Growth accelerated 2 >= +2 SD (standard deviatiN/A
Growth accelerated Definition A disorder characterized bN/A
Hyperparathyroidism 1 Mild symptoms; interventiN/A
Hyperparathyroidism 2 Moderate symptoms; medic N/A
Hyperparathyroidism Definition A disorder characterized bN/A
Hyperthyroidism 1 Asymptomatic; clinical or N/A
Hyperthyroidism 2 Symptomatic; thyroid suppN/A
Hyperthyroidism 3 Severe symptoms; limitingN/A
Hyperthyroidism 4 Life-threatening consequen N/A
Hyperthyroidism 5 Death N/A
Hyperthyroidism Definition A disorder characterized N/A
Hypoparathyroidism 1 Asymptomatic; clinical or N/A
Hypoparathyroidism 2 Moderate symptoms; medic N/A
Hypoparathyroidism 3 Severe symptoms; medicalN/A i
Hypoparathyroidism 4 Life-threatening consequen N/A
Hypoparathyroidism 5 Death N/A
Hypoparathyroidism Definition A disorder characterized bN/A
Hypothyroidism 1 Asymptomatic; clinical or N/A
Hypothyroidism 2 Symptomatic; thyroid replN/A
Hypothyroidism 3 Severe symptoms; limitingN/A
Hypothyroidism 4 Life-threatening consequen N/A
Hypothyroidism 5 Death N/A
Hypothyroidism Definition A disorder characterized bN/A
Precocious puberty 1 Physical signs of puberty N/A
Precocious puberty 2 Physical signs and biochemN/A
Precocious puberty Definition A disorder characterized bN/A
Virilization 1 Mild symptoms; interventiN/A
Virilization 2 Moderate symptoms; medic N/A
Virilization Definition A disorder characterized bN/A
Blurred vision 1 Intervention not indicatedN/A
Blurred vision 2 Symptomatic; moderate decr N/A
Blurred vision 3 Symptomatic with markedN/A de
Blurred vision Definition A disorder characterized bN/A
Cataract 1 Asymptomatic; clinical or N/A
Cataract 2 Symptomatic; moderate decrease
N/A in visual acuity (best corrected visual acuit
Cataract 3 Symptomatic with markedN/A de
Cataract 4 Best corrected visual acui N/A
Cataract Definition A disorder characterized by N/A
Conjunctivitis 1 Asymptomatic or mild symp N/A
Conjunctivitis 2 Symptomatic; moderate decr N/A
Conjunctivitis 3 Symptomatic with markedN/A de
Conjunctivitis Definition A disorder characterized bN/A
Corneal ulcer 3 Corneal ulcer without perfN/A
Corneal ulcer 3 Corneal ulcer without perfN/A
Corneal ulcer 4 Perforation in the affecte N/A
Corneal ulcer Definition A disorder characterized by N/A
Dry eye 1 Asymptomatic; clinical or N/A
Dry eye 2 Symptomatic; moderate decr N/A
Dry eye 3 Symptomatic with markedN/A de
Dry eye Definition A disorder characterized bN/A
Extraocular muscle paresis1 Asymptomatic; clinical or N/A
Extraocular muscle paresis2 Unilateral paresis without N/A
Extraocular muscle paresis3 Bilateral paresis or unilat N/A
Extraocular muscle paresisDefinition A disorder characterized bN/A
Eye disorders - Other, spec1 Asymptomatic or mild sympt N/A
Eye disorders - Other, spec2 Moderate; minimal, local oN/A
Eye disorders - Other, spec3 Severe or medically signif N/A
Eye disorders - Other, spec4 Sight-threatening conseque N/A
Eye pain 1 Mild pain N/A
Eye pain 2 Moderate pain; limiting i N/A
Eye pain 3 Severe pain; limiting self N/A
Eye pain Definition A disorder characterized bN/A
Eyelid function disorder 1 Asymptomatic; clinical or N/A
Eyelid function disorder 2 Symptomatic; nonoperative N/A
Eyelid function disorder 3 Limiting self care ADL; opeN/A
Eyelid function disorder Definition A disorder characterized bN/A
Flashing lights 1 Symptomatic but not limitN/A
Flashing lights 2 Limiting instrumental ADLN/A
Flashing lights 3 Limiting self care ADL N/A
Flashing lights Definition A disorder characterized by N/A
Floaters 1 Symptomatic but not limitN/A
Floaters 2 Limiting instrumental ADLN/A
Floaters 3 Limiting self care ADL N/A
Floaters Definition A disorder characterized bN/A
Glaucoma 1 Less than 8 mmHg of elevate N/A
Glaucoma 2 EIOP which can be reducedN/A
Glaucoma 3 EIOP causing visual field deN/A
Glaucoma 4 Visual field deficit within N/A
Glaucoma Definition A disorder characterized bN/A
Keratitis 2 Symptomatic; moderate decr N/A
Keratitis 3 Symptomatic with markedN/A de
Keratitis 4 Perforation; best correcte N/A
Keratitis Definition A disorder characterized bN/A
Night blindness 1 Symptomatic but not limitN/A
Night blindness 2 Symptomatic; moderate decr N/A
Night blindness 3 Symptomatic with markedN/A de
Night blindness 4 Best corrected visual acui N/A
Night blindness Definition A disorder characterized by N/A
Optic nerve disorder 1 Asymptomatic; clinical or N/A
Optic nerve disorder 2 Moderate decrease in visua N/A
Optic nerve disorder 3 Marked decrease in visual N/A
Optic nerve disorder 4 Best corrected visual acui N/A
Optic nerve disorder Definition A disorder characterized bN/A
Papilledema 1 Asymptomatic; no visual fie N/A
Papilledema 2 Symptomatic; moderate decr N/A
Papilledema 3 Symptomatic with markedN/A de
Papilledema 4 Best corrected visual acui N/A
Papilledema Definition A disorder characterized bN/A
Photophobia 1 Symptomatic but not limitN/A
Photophobia 2 Limiting instrumental ADLN/A
Photophobia 3 Limiting self care ADL N/A
Photophobia Definition A disorder characterized bN/A
Retinal detachment 3 Macular sparing rhegmat N/A
Retinal detachment 4 Macula-off rhegmatogenou N/A
Retinal detachment Definition A disorder characterized bN/A
Retinal detachment 4 Macula-off rhegmatogenou N/A
Retinal tear 2 No retinal detachment andN/A
Retinal tear Definition A disorder characterized bN/A
Retinal vascular disorder 2 Retinal vascular disorder N/A
Retinal vascular disorder 3 Retinal vascular disorder N/A
Retinal vascular disorder Definition A disorder characterized byN/A
Retinopathy 1 Asymptomatic; clinical or N/A
Retinopathy 2 Symptomatic; moderate decr N/A
Retinopathy 3 Symptomatic with markedN/A de
Retinopathy 4 Best corrected visual acui N/A
Retinopathy Definition A disorder involving the reN/A
Scleral disorder 1 No change in vision from bN/A
Scleral disorder 2 Symptomatic; moderate decr N/A
Scleral disorder 3 Symptomatic with markedN/A de
Scleral disorder 4 Best corrected visual acui N/A
Scleral disorder Definition A disorder characterized bN/A
Uveitis 1 Anterior uveitis with traceN/A
Uveitis 2 Anterior uveitis with 1+ orN/A
Uveitis 3 Anterior uveitis with 3+ orN/A
Uveitis 4 Best corrected visual acui N/A
Uveitis Definition A disorder characterized bN/A
Vitreous hemorrhage 1 Intervention not indicatedN/A
Vitreous hemorrhage 2 Symptomatic; moderate decr N/A
Vitreous hemorrhage 3 Symptomatic with markedN/A de
Vitreous hemorrhage 4 Best corrected visual acui N/A
Vitreous hemorrhage Definition A disorder characterized bN/A
Watering eyes 1 Intervention not indicatedN/A
Watering eyes 2 Symptomatic; moderate decr N/A
Watering eyes 3 Marked decrease in visual N/A
Watering eyes Definition A disorder characterized bN/A
Abdominal distension 1 Asymptomatic; clinical or N/A
Abdominal distension 2 Symptomatic; limiting ins N/A
Abdominal distension 3 Severe discomfort; limitingN/A
Abdominal distension Definition A disorder characterized N/A
Abdominal pain 1 Mild pain N/A
Abdominal pain 2 Moderate pain; limiting i N/A
Abdominal pain 3 Severe pain; limiting self N/A
Abdominal pain Definition A disorder characterized bN/A
Anal fistula 1 Asymptomatic N/A
Anal fistula 2 Symptomatic, invasive inteN/A
Anal fistula 3 Invasive intervention indi N/A
Anal fistula 4 Life-threatening consequen N/A
Anal fistula 5 Death N/A
Anal fistula Definition A disorder characterized N/A
Anal hemorrhage 1 Mild symptoms; interventiN/A
Anal hemorrhage 2 Moderate symptoms; interN/A
Anal hemorrhage 3 Transfusion indicated; invaN/A
Anal hemorrhage 4 Life-threatening consequen N/A
Anal hemorrhage 5 Death N/A
Anal hemorrhage Definition A disorder characterized bN/A
Anal ulcer 4 Life-threatening consequen N/A
Anal ulcer 5 Death N/A
Anal mucositis 1 Asymptomatic or mild symp N/A
Anal mucositis 2 Symptomatic; medical inter N/A
Anal mucositis 3 Severe symptoms; limitingN/A
Anal mucositis Definition A disorder characterized N/A
Anal necrosis 3 TPN or hospitalization indiN/A
Anal necrosis 4 Life-threatening consequen N/A
Anal necrosis 5 Death N/A
Anal necrosis Definition A disorder characterized byN/A
Anal pain 1 Mild pain N/A
Anal pain 2 Moderate pain; limiting i N/A
Anal pain 3 Severe pain; limiting self N/A
Anal pain Definition A disorder characterized bN/A
Anal stenosis 1 Asymptomatic; clinical or N/A
Anal stenosis 2 Symptomatic; altered GI f N/A
Anal stenosis 3 Symptomatic and severelyN/A a
Anal stenosis 4 Life-threatening consequen N/A
Anal stenosis 5 Death N/A
Anal stenosis Definition A disorder characterized bN/A
Anal ulcer 1 Asymptomatic; clinical or N/A
Anal ulcer 2 Symptomatic; altered GI f N/A
Anal ulcer 3 Severely altered GI functioN/A
Anal ulcer 4 Life-threatening consequen N/A
Anal ulcer 5 Death N/A
Anal ulcer Definition A disorder characterized bN/A
Ascites 1 Asymptomatic; clinical or N/A
Ascites 2 Symptomatic; medical inteN/A
Ascites 3 Severe symptoms; invasiveN/A
Ascites 4 Life-threatening consequen N/A
Ascites 5 Death N/A
Ascites Definition A disorder characterized bN/A
Bloating 1 No change in bowel functio N/A
Bloating 2 Symptomatic, decreased or N/A
Bloating Definition A disorder characterized bN/A
Cecal hemorrhage 1 Mild symptoms; interventiN/A
Cecal hemorrhage 2 Moderate symptoms; interN/A
Cecal hemorrhage 3 Transfusion indicated; invaN/A
Cecal hemorrhage 4 Life-threatening consequen N/A
Cecal hemorrhage 5 Death N/A
Cecal hemorrhage Definition A disorder characterized N/A
Cheilitis 1 Asymptomatic; clinical or N/A
Cheilitis 2 Moderate symptoms; limitN/A
Cheilitis 3 Severe symptoms; limitingN/A
Cheilitis Definition A disorder characterized bN/A
Colitis 1 Asymptomatic; clinical or N/A
Colitis 2 Abdominal pain; mucus orN/A
Colitis 3 Severe abdominal pain; per N/A
Colitis 4 Life-threatening consequen N/A
Colitis 5 Death N/A
Colitis Definition A disorder characterized bN/A
Colonic fistula 1 Asymptomatic N/A
Colonic fistula 2 Symptomatic, invasive inteN/A
Colonic fistula 3 Invasive intervention indi N/A
Colonic fistula 4 Life-threatening consequen N/A
Colonic fistula 5 Death N/A
Colonic fistula Definition A disorder characterized N/A
Colonic hemorrhage 1 Mild symptoms; interventiN/A
Colonic hemorrhage 2 Moderate symptoms; interN/A
Colonic hemorrhage 3 Transfusion indicated; invaN/A
Colonic hemorrhage 4 Life-threatening consequen N/A
Colonic hemorrhage 5 Death N/A
Colonic hemorrhage Definition A disorder characterized bN/A
Colonic obstruction 1 Asymptomatic; clinical or N/A
Colonic obstruction 2 Symptomatic; altered GI f N/A
Colonic obstruction 3 Hospitalization indicated; N/A
Colonic obstruction 4 Life-threatening consequen N/A
Colonic obstruction 5 Death N/A
Colonic obstruction Definition A disorder characterized bN/A
Colonic perforation 2 Invasive intervention not N/A
Colonic perforation 3 Invasive intervention indi N/A
Colonic perforation 4 Life-threatening consequen N/A
Colonic perforation 5 Death N/A
Colonic perforation Definition A disorder characterized byN/A
Colonic stenosis 1 Asymptomatic; clinical or N/A
Colonic stenosis 2 Symptomatic; altered GI f N/A
Colonic stenosis 3 Severely altered GI functioN/A
Colonic stenosis 4 Life-threatening consequen N/A
Colonic stenosis 5 Death N/A
Colonic stenosis Definition A disorder characterized bN/A
Colonic ulcer 1 Asymptomatic; clinical or N/A
Colonic ulcer 2 Symptomatic; altered GI f N/A
Colonic ulcer 3 Severely altered GI functioN/A
Colonic ulcer 4 Life-threatening consequen N/A
Colonic ulcer 5 Death N/A
Colonic ulcer Definition A disorder characterized bN/A
Constipation 1 Occasional or intermittentN/A
Constipation 2 Persistent symptoms with N/Ar
Constipation 3 Obstipation with manual ev N/A
Constipation 4 Life-threatening consequen N/A
Constipation 5 Death N/A
Constipation Definition A disorder characterized by N/A
Dental caries 1 One or more dental caries,N/A
Dental caries 2 Dental caries involving theN/A
Dental caries 3 Dental caries resulting in pN/A
Dental caries Definition A disorder characterized bN/A
Diarrhea 1 Increase of <4 stools per N/A
Diarrhea 2 Increase of 4 - 6 stools p N/A
Diarrhea 3 Increase of >=7 stools per N/A
Diarrhea 4 Life-threatening consequen N/A
Diarrhea 5 Death N/A
Diarrhea Definition A disorder characterized N/A
Dry mouth 1 Symptomatic (e.g., dry or tN/A
Dry mouth 2 Moderate symptoms; oralN/A in
Dry mouth 3 Inability to adequately al N/A
Dry mouth Definition A disorder characterized by N/A
Duodenal fistula 1 Asymptomatic N/A
Duodenal fistula 2 Symptomatic, invasive inteN/A
Duodenal fistula 3 Invasive intervention indi N/A
Duodenal fistula 4 Life-threatening consequen N/A
Duodenal fistula 5 Death N/A
Duodenal fistula Definition A disorder characterized N/A
Duodenal hemorrhage 1 Mild symptoms; interventiN/A
Duodenal hemorrhage 2 Moderate symptoms; interN/A
Duodenal hemorrhage 3 Transfusion indicated; invaN/A
Duodenal hemorrhage 4 Life-threatening consequen N/A
Duodenal hemorrhage 5 Death N/A
Duodenal hemorrhage Definition A disorder characterized N/A
Duodenal obstruction 1 Asymptomatic; clinical or N/A
Duodenal obstruction 2 Symptomatic; altered GI f N/A
Duodenal obstruction 3 Hospitalization indicated; N/A
Duodenal obstruction 4 Life-threatening consequen N/A
Duodenal obstruction 5 Death N/A
Duodenal obstruction Definition A disorder characterized N/A
Duodenal perforation 2 Invasive intervention not N/A
Duodenal perforation 3 Invasive intervention indi N/A
Duodenal perforation 4 Life-threatening consequen N/A
Duodenal perforation 5 Death N/A
Duodenal perforation Definition A disorder characterized bN/A
Duodenal stenosis 1 Asymptomatic; clinical or N/A
Duodenal stenosis 2 Symptomatic; altered GI f N/A
Duodenal stenosis 3 Severely altered GI functioN/A
Duodenal stenosis 4 Life-threatening consequen N/A
Duodenal stenosis 5 Death N/A
Duodenal stenosis Definition A disorder characterized N/A
Duodenal ulcer 1 Asymptomatic; clinical or N/A
Duodenal ulcer 2 Symptomatic; medical inter N/A
Duodenal ulcer 3 Severely altered GI functioN/A
Duodenal ulcer 4 Life-threatening consequen N/A
Duodenal ulcer 5 Death N/A
Duodenal ulcer Definition A disorder characterized bN/A
Dyspepsia 1 Mild symptoms; interventiN/A
Dyspepsia 2 Moderate symptoms; medic N/A
Dyspepsia 3 Severe symptoms; operativN/A
Dyspepsia Definition A disorder characterized bN/A
Dysphagia 1 Symptomatic, able to eat rN/A
Dysphagia 2 Symptomatic and altered N/A
Dysphagia 3 Severely altered eating/swN/A
Dysphagia 4 Life-threatening consequen N/A
Dysphagia 5 Death N/A
Dysphagia Definition A disorder characterized byN/A
Enterocolitis 1 Asymptomatic; clinical or N/A
Enterocolitis 2 Abdominal pain; mucus orN/A
Enterocolitis 3 Severe or persistent abdomiN/A
Enterocolitis 4 Life-threatening consequen N/A
Enterocolitis 5 Death N/A
Enterocolitis Definition A disorder characterized bN/A
Enterovesical fistula 1 Asymptomatic N/A
Enterovesical fistula 2 Symptomatic, invasive inteN/A
Enterovesical fistula 3 Invasive intervention indi N/A
Enterovesical fistula 4 Life-threatening consequen N/A
Enterovesical fistula 5 Death N/A
Enterovesical fistula Definition A disorder characterized N/A
Esophageal fistula 1 Asymptomatic N/A
Esophageal fistula 2 Symptomatic, invasive inteN/A
Esophageal fistula 3 Invasive intervention indi N/A
Esophageal fistula 4 Life-threatening consequen N/A
Esophageal fistula 5 Death N/A
Esophageal fistula Definition A disorder characterized N/A
Esophageal hemorrhage 1 Mild symptoms; interventiN/A
Esophageal hemorrhage 2 Moderate symptoms; interN/A
Esophageal hemorrhage 3 Transfusion indicated; invaN/A
Esophageal hemorrhage 4 Life-threatening consequen N/A
Esophageal hemorrhage 5 Death N/A
Esophageal hemorrhage Definition A disorder characterized N/A
Esophageal necrosis 3 Inability to aliment adequaN/A
Esophageal necrosis 4 Life-threatening consequen N/A
Esophageal necrosis 5 Death N/A
Esophageal necrosis Definition A disorder characterized bN/A
Esophageal obstruction 1 Asymptomatic; clinical or N/A
Esophageal obstruction 2 Symptomatic; altered GI fuN/A
Esophageal obstruction 3 Hospitalization indicated; N/A
Esophageal obstruction 4 Life-threatening consequen N/A
Esophageal obstruction 5 Death N/A
Esophageal obstruction Definition A disorder characterized bN/A
Esophageal pain 1 Mild pain N/A
Esophageal pain 2 Moderate pain; limiting i N/A
Esophageal pain 3 Severe pain; limiting self N/A
Esophageal pain Definition A disorder characterized bN/A
Esophageal perforation 2 Invasive intervention not N/A
Esophageal perforation 3 Invasive intervention indi N/A
Esophageal perforation 4 Life-threatening consequen N/A
Esophageal perforation 5 Death N/A
Esophageal perforation Definition A disorder characterized bN/A
Esophageal stenosis 1 Asymptomatic; clinical or N/A
Esophageal stenosis 2 Symptomatic; altered GI f N/A
Esophageal stenosis 3 Severely altered GI functioN/A
Esophageal stenosis 4 Life-threatening consequen N/A
Esophageal stenosis 5 Death N/A
Esophageal stenosis Definition A disorder characterized N/A
Esophageal ulcer 1 Asymptomatic; clinical or N/A
Esophageal ulcer 2 Symptomatic; altered GI fuN/A
Esophageal ulcer 3 Severely altered GI functioN/A
Esophageal ulcer 4 Life-threatening consequen N/A
Esophageal ulcer 5 Death N/A
Esophageal ulcer Definition A disorder characterized bN/A
Esophageal varices hemor2 Self-limited; intervention N/A
Esophageal varices hemor3 Transfusion indicated; invaN/A
Esophageal varices hemor4 Life-threatening consequen N/A
Esophageal varices hemor5 Death N/A
Esophageal varices hemorDefinition A disorder characterized bN/A
Esophagitis 1 Asymptomatic; clinical or N/A
Esophagitis 2 Symptomatic; altered eatiN/A
Esophagitis 3 Severely altered eating/swN/A
Esophagitis 4 Life-threatening consequen N/A
Esophagitis 5 Death N/A
Esophagitis Definition A disorder characterized bN/A
Fecal incontinence 1 Occasional use of pads re N/A
Fecal incontinence 2 Daily use of pads requiredN/A
Fecal incontinence 3 Severe symptoms; electiveN/A
Fecal incontinence Definition A disorder characterized byN/A
Flatulence 1 Mild symptoms; interventiN/A
Flatulence 2 Moderate; persistent; psy N/A
Flatulence Definition A disorder characterized bN/A
Gastric fistula 1 Asymptomatic N/A
Gastric fistula 2 Symptomatic, invasive inteN/A
Gastric fistula 3 Invasive intervention indi N/A
Gastric fistula 4 Life-threatening consequen N/A
Gastric fistula 5 Death N/A
Gastric fistula Definition A disorder characterized N/A
Gastric hemorrhage 1 Mild symptoms; interventiN/A
Gastric hemorrhage 2 Moderate symptoms; interN/A
Gastric hemorrhage 3 Transfusion indicated; invaN/A
Gastric hemorrhage 4 Life-threatening consequen N/A
Gastric hemorrhage 5 Death N/A
Gastric hemorrhage Definition A disorder characterized bN/A
Gastric necrosis 3 Inability to aliment adequaN/A
Gastric necrosis 4 Life-threatening consequen N/A
Gastric necrosis 5 Death N/A
Gastric necrosis Definition A disorder characterized byN/A
Gastric perforation 2 Invasive intervention not N/A
Gastric perforation 3 Invasive intervention indi N/A
Gastric perforation 4 Life-threatening consequen N/A
Gastric perforation 5 Death N/A
Gastric perforation Definition A disorder characterized bN/A
Gastric stenosis 1 Asymptomatic; clinical or N/A
Gastric stenosis 2 Symptomatic; altered GI f N/A
Gastric stenosis 3 Severely altered GI functioN/A
Gastric stenosis 4 Life-threatening consequen N/A
Gastric stenosis 5 Death N/A
Gastric stenosis Definition A disorder characterized N/A
Gastric ulcer 1 Asymptomatic; clinical or N/A
Gastric ulcer 2 Symptomatic; altered GI fuN/A
Gastric ulcer 3 Severely altered GI functioN/A
Gastric ulcer 4 Life-threatening consequen N/A
Gastric ulcer 5 Death N/A
Gastric ulcer Definition A disorder characterized bN/A
Gastritis 1 Asymptomatic; clinical or N/A
Gastritis 2 Symptomatic; altered GI fuN/A
Gastritis 3 Severely altered eating or N/A
Gastritis 4 Life-threatening consequen N/A
Gastritis 5 Death N/A
Gastritis Definition A disorder characterized N/A
Gastroesophageal reflux d1 Mild symptoms; interventiN/A
Gastroesophageal reflux d2 Moderate symptoms; medic N/A
Gastroesophageal reflux d3 Severe symptoms; operativN/A
Gastroesophageal reflux dDefinition A disorder characterized bN/A
Gastrointestinal disorders 1 Asymptomatic or mild sympt N/A
Gastrointestinal disorders 2 Moderate; minimal, local oN/A
Gastrointestinal disorders 3 Severe or medically signifiN/A
Gastrointestinal disorders 4 Life-threatening consequen N/A
Gastrointestinal disorders 5 Death N/A
Gastrointestinal fistula 1 Asymptomatic N/A
Gastrointestinal fistula 2 Symptomatic, invasive inteN/A
Gastrointestinal fistula 3 Invasive intervention indi N/A
Gastrointestinal fistula 4 Life-threatening consequen N/A
Gastrointestinal fistula 5 Death N/A
Gastrointestinal fistula Definition A disorder characterized N/A
Gastrointestinal pain 1 Mild pain N/A
Gastrointestinal pain 2 Moderate pain; limiting i N/A
Gastrointestinal pain 3 Severe pain; limiting self N/A
Gastrointestinal pain Definition A disorder characterized bN/A
Gastroparesis 1 Mild nausea, early satiety N/A
Gastroparesis 2 Moderate symptoms; ableN/A t
Gastroparesis 3 Weight loss >=20% from bas N/A
Gastroparesis Definition A disorder characterized bN/A
Gingival pain 1 Mild pain N/A
Gingival pain 2 Moderate pain interferingN/A
Gingival pain 3 Severe pain; inability to al N/A
Gingival pain Definition A disorder characterized bN/A
Hemorrhoidal hemorrhag 1 Mild symptoms; interventiN/A
Hemorrhoidal hemorrhag 2 Moderate symptoms; interN/A
Hemorrhoidal hemorrhag 3 Transfusion indicated; invaN/A
Hemorrhoidal hemorrhag 4 Life-threatening consequen N/A
Hemorrhoidal hemorrhag 5 Death N/A
Hemorrhoidal hemorrhag Definition A disorder characterized N/A
Hemorrhoids 1 Asymptomatic; clinical or N/A
Hemorrhoids 2 Symptomatic; banding or m N/A
Hemorrhoids 3 Severe symptoms; invasiveN/A
Hemorrhoids Definition A disorder characterized bN/A
Ileal fistula 1 Asymptomatic N/A
Ileal fistula 2 Symptomatic, invasive inteN/A
Ileal fistula 3 Invasive intervention indi N/A
Ileal fistula 4 Life-threatening consequen N/A
Ileal fistula 5 Death N/A
Ileal fistula Definition A disorder characterized N/A
Ileal hemorrhage 1 Mild symptoms; interventiN/A
Ileal hemorrhage 2 Moderate symptoms; interN/A
Ileal hemorrhage 3 Transfusion indicated; invaN/A
Ileal hemorrhage 4 Life-threatening consequen N/A
Ileal hemorrhage 5 Death N/A
Ileal hemorrhage Definition A disorder characterized byN/A
Ileal obstruction 1 Asymptomatic; clinical or N/A
Ileal obstruction 2 Symptomatic; altered GI fuN/A
Ileal obstruction 3 Hospitalization indicated; N/A
Ileal obstruction 4 Life-threatening consequen N/A
Ileal obstruction 5 Death N/A
Ileal obstruction Definition A disorder characterized bN/A
Ileal perforation 2 Invasive intervention not N/A
Ileal perforation 3 Invasive intervention indi N/A
Ileal perforation 4 Life-threatening consequen N/A
Ileal perforation 5 Death N/A
Ileal perforation Definition A disorder characterized byN/A
Ileal stenosis 1 Asymptomatic; clinical or N/A
Ileal stenosis 2 Symptomatic; altered GI f N/A
Ileal stenosis 3 Severely altered GI functioN/A
Ileal stenosis 4 Life-threatening consequen N/A
Ileal stenosis 5 Death N/A
Ileal stenosis Definition A disorder characterized bN/A
Ileal ulcer 1 Asymptomatic; clinical or N/A
Ileal ulcer 2 Symptomatic; altered GI f N/A
Ileal ulcer 3 Severely altered GI functioN/A
Ileal ulcer 4 Life-threatening consequen N/A
Ileal ulcer 5 Death N/A
Ileal ulcer Definition A disorder characterized bN/A
Ileus 2 Symptomatic; altered GI fuN/A
Ileus 3 Severely altered GI functi N/A
Ileus 4 Life-threatening consequen N/A
Ileus 5 Death N/A
Ileus Definition A disorder characterized byN/A
Intra-abdominal hemorrh 2 Moderate symptoms; interN/A
Intra-abdominal hemorrh 3 Transfusion indicated; invaN/A
Intra-abdominal hemorrh 4 Life-threatening consequen N/A
Intra-abdominal hemorrh 5 Death N/A
Intra-abdominal hemorrh Definition A disorder characterized bN/A
Jejunal fistula 1 Asymptomatic N/A
Jejunal fistula 2 Symptomatic, invasive inteN/A
Jejunal fistula 3 Invasive intervention indi N/A
Jejunal fistula 4 Life-threatening consequen N/A
Jejunal fistula 5 Death N/A
Jejunal fistula Definition A disorder characterized N/A
Jejunal hemorrhage 1 Mild symptoms; interventiN/A
Jejunal hemorrhage 2 Moderate symptoms; interN/A
Jejunal hemorrhage 3 Transfusion indicated; invaN/A
Jejunal hemorrhage 4 Life-threatening consequen N/A
Jejunal hemorrhage 5 Death N/A
Jejunal hemorrhage Definition A disorder characterized bN/A
Jejunal obstruction 1 Asymptomatic; clinical or N/A
Jejunal obstruction 2 Symptomatic; altered GI fuN/A
Jejunal obstruction 3 Hospitalization indicated; N/A
Jejunal obstruction 4 Life-threatening consequen N/A
Jejunal obstruction 5 Death N/A
Jejunal obstruction Definition A disorder characterized bN/A
Jejunal perforation 2 Invasive intervention not N/A
Jejunal perforation 3 Invasive intervention indi N/A
Jejunal perforation 4 Life-threatening consequen N/A
Jejunal perforation 5 Death N/A
Jejunal perforation Definition A disorder characterized byN/A
Jejunal stenosis 1 Asymptomatic; clinical or N/A
Jejunal stenosis 2 Symptomatic; altered GI f N/A
Jejunal stenosis 3 Severely altered GI functioN/A
Jejunal stenosis 4 Life-threatening consequen N/A
Jejunal stenosis 5 Death N/A
Jejunal stenosis Definition A disorder characterized bN/A
Jejunal ulcer 1 Asymptomatic; clinical or N/A
Jejunal ulcer 2 Symptomatic; altered GI f N/A
Jejunal ulcer 3 Severely altered GI functioN/A
Jejunal ulcer 4 Life-threatening consequen N/A
Jejunal ulcer 5 Death N/A
Jejunal ulcer Definition A disorder characterized bN/A
Lip pain 1 Mild pain N/A
Lip pain 2 Moderate pain; limiting i N/A
Lip pain 3 Severe pain; limiting self N/A
Lip pain Definition A disorder characterized bN/A
Lower gastrointestinal he 1 Mild symptoms; interventiN/A
Lower gastrointestinal he 2 Moderate symptoms; interN/A
Lower gastrointestinal he 3 Transfusion indicated; invaN/A
Lower gastrointestinal he 4 Life-threatening consequen N/A
Lower gastrointestinal he 5 Death N/A
Lower gastrointestinal he Definition A disorder characterized byN/A
Malabsorption 2 Altered diet; oral intervenN/A
Malabsorption 3 Inability to aliment adequ N/A
Malabsorption 4 Life-threatening consequen N/A
Malabsorption 5 Death N/A
Malabsorption Definition A disorder characterized bN/A
Mucositis oral 1 Asymptomatic or mild symp N/A
Mucositis oral 2 Moderate pain or ulcer thaN/A
Mucositis oral 3 Severe pain; interfering wiN/A
Mucositis oral 4 Life-threatening consequen N/A
Mucositis oral 5 Death N/A
Mucositis oral Definition A disorder characterized bN/A
Nausea 1 Loss of appetite without alN/A
Nausea 2 Oral intake decreased withN/A
Nausea 3 Inadequate oral caloric or N/A
Nausea Definition A disorder characterized bN/A
Obstruction gastric 1 Asymptomatic; clinical or N/A
Obstruction gastric 2 Symptomatic; altered GI fuN/A
Obstruction gastric 3 Hospitalization indicated; N/A
Obstruction gastric 4 Life-threatening consequen N/A
Obstruction gastric 5 Death N/A
Obstruction gastric Definition A disorder characterized bN/A
Oral cavity fistula 1 Asymptomatic N/A
Oral cavity fistula 2 Symptomatic, invasive inteN/A
Oral cavity fistula 3 Invasive intervention indi N/A
Oral cavity fistula 4 Life-threatening consequen N/A
Oral cavity fistula 5 Death N/A
Oral cavity fistula Definition A disorder characterized N/A
Oral dysesthesia 1 Mild discomfort; not interfN/A
Oral dysesthesia 2 Moderate pain; interferingN/A
Oral dysesthesia 3 Disabling pain; tube feedi N/A
Oral dysesthesia Definition A disorder characterized bN/A
Oral hemorrhage 1 Mild symptoms; interventiN/A
Oral hemorrhage 2 Moderate symptoms; interN/A
Oral hemorrhage 3 Transfusion indicated; invaN/A
Oral hemorrhage 4 Life-threatening consequen N/A
Oral hemorrhage 5 Death N/A
Oral hemorrhage Definition A disorder characterized N/A
Oral pain 1 Mild pain N/A
Oral pain 2 Moderate pain; limiting i N/A
Oral pain 3 Severe pain; limiting self N/A
Oral pain Definition A disorder characterized bN/A
Pancreatic duct stenosis 1 Asymptomatic; clinical or N/A
Pancreatic duct stenosis 2 Symptomatic; altered GI f N/A
Pancreatic duct stenosis 3 Severely altered GI functioN/A
Pancreatic duct stenosis 4 Life-threatening consequen N/A
Pancreatic duct stenosis 5 Death N/A
Pancreatic duct stenosis Definition A disorder characterized bN/A
Pancreatic fistula 1 Asymptomatic N/A
Pancreatic fistula 2 Symptomatic, invasive inteN/A
Pancreatic fistula 3 Invasive intervention indi N/A
Pancreatic fistula 4 Life-threatening consequen N/A
Pancreatic fistula 5 Death N/A
Pancreatic fistula Definition A disorder characterized N/A
Pancreatic hemorrhage 1 Mild symptoms; interventiN/A
Pancreatic hemorrhage 2 Moderate symptoms; interN/A
Pancreatic hemorrhage 3 Transfusion indicated; invaN/A
Pancreatic hemorrhage 4 Life-threatening consequen N/A
Pancreatic hemorrhage 5 Death N/A
Pancreatic hemorrhage Definition A disorder characterized bN/A
Pancreatic necrosis 3 Tube feeding or TPN indicaN/A
Pancreatic necrosis 4 Life-threatening consequen N/A
Pancreatic necrosis 5 Death N/A
Pancreatic necrosis Definition A disorder characterized bN/A
Pancreatitis 2 Enzyme elevation; radiologN/A
Pancreatitis 3 Severe pain; vomiting; mediN/A
Pancreatitis 4 Life-threatening consequen N/A
Pancreatitis 5 Death N/A
Pancreatitis Definition A disorder characterized N/A
Periodontal disease 1 Gingival recession or gingiN/A
Periodontal disease 2 Moderate gingival recessioN/A
Periodontal disease 3 Spontaneous bleeding; seve N/A
Periodontal disease Definition A disorder in the gingival N/A
Peritoneal necrosis 3 Tube feeding or TPN indicaN/A
Peritoneal necrosis 4 Life-threatening consequen N/A
Peritoneal necrosis 5 Death N/A
Peritoneal necrosis Definition A disorder characterized bN/A
Proctitis 1 Rectal discomfort, interveN/A
Proctitis 2 Symptomatic (e.g., rectal N/A
Proctitis 3 Severe symptoms; fecal urg N/A
Proctitis 4 Life-threatening consequen N/A
Proctitis 5 Death N/A
Proctitis Definition A disorder characterized bN/A
Rectal fistula 1 Asymptomatic N/A
Rectal fistula 2 Symptomatic, invasive inteN/A
Rectal fistula 3 Invasive intervention indi N/A
Rectal fistula 4 Life-threatening consequen N/A
Rectal fistula 5 Death N/A
Rectal fistula Definition A disorder characterized N/A
Rectal hemorrhage 1 Mild symptoms; interventiN/A
Rectal hemorrhage 2 Moderate symptoms; interN/A
Rectal hemorrhage 3 Transfusion indicated; invaN/A
Rectal hemorrhage 4 Life-threatening consequen N/A
Rectal hemorrhage 5 Death N/A
Rectal hemorrhage Definition A disorder characterized bN/A
Rectal mucositis 1 Asymptomatic or mild symp N/A
Rectal mucositis 2 Symptomatic; medical inter N/A
Rectal mucositis 3 Severe symptoms; limitingN/A
Rectal mucositis 4 Life-threatening consequen N/A
Rectal mucositis 5 Death N/A
Rectal mucositis Definition A disorder characterized N/A
Rectal necrosis 3 Tube feeding or TPN indicaN/A
Rectal necrosis 4 Life-threatening consequen N/A
Rectal necrosis 5 Death N/A
Rectal necrosis Definition A disorder characterized by N/A
Rectal obstruction 1 Asymptomatic; clinical or N/A
Rectal obstruction 2 Symptomatic; altered GI fuN/A
Rectal obstruction 3 Hospitalization indicated; N/A
Rectal obstruction 4 Life-threatening consequen N/A
Rectal obstruction 5 Death N/A
Rectal obstruction Definition A disorder characterized bN/A
Rectal pain 1 Mild pain N/A
Rectal pain 2 Moderate pain; limiting i N/A
Rectal pain 3 Severe pain; limiting self N/A
Rectal pain Definition A disorder characterized bN/A
Rectal perforation 2 Invasive intervention not N/A
Rectal perforation 3 Invasive intervention indi N/A
Rectal perforation 4 Life-threatening consequen N/A
Rectal perforation 5 Death N/A
Rectal perforation Definition A disorder characterized by N/A
Rectal stenosis 1 Asymptomatic; clinical or N/A
Rectal stenosis 2 Symptomatic; altered GI f N/A
Rectal stenosis 3 Severely altered GI functioN/A
Rectal stenosis 4 Life-threatening consequen N/A
Rectal stenosis 5 Death N/A
Rectal stenosis Definition A disorder characterized bN/A
Rectal ulcer 1 Asymptomatic; clinical or N/A
Rectal ulcer 2 Symptomatic; altered GI fun N/A
Rectal ulcer 3 Severely altered GI functioN/A
Rectal ulcer 4 Life-threatening consequen N/A
Rectal ulcer 5 Death N/A
Rectal ulcer Definition A disorder characterized bN/A
Retroperitoneal hemorrha2 Self-limited; intervention N/A
Retroperitoneal hemorrha3 Transfusion indicated; invaN/A
Retroperitoneal hemorrha4 Life-threatening consequen N/A
Retroperitoneal hemorrha5 Death N/A
Retroperitoneal hemorrhaDefinition A disorder characterized bN/A
Salivary duct inflammatio 1 Slightly thickened saliva; slN/A
Salivary duct inflammatio 2 Thick, ropy, sticky saliva; N/A
Salivary duct inflammatio 3 Acute salivary gland necrosN/A
Salivary duct inflammatio 4 Life-threatening consequen N/A
Salivary duct inflammatio 5 Death N/A
Salivary duct inflammatio Definition A disorder characterized bN/A
Salivary gland fistula 1 Asymptomatic N/A
Salivary gland fistula 2 Symptomatic, invasive inteN/A
Salivary gland fistula 3 Invasive intervention indi N/A
Salivary gland fistula 4 Life-threatening consequen N/A
Salivary gland fistula 5 Death N/A
Salivary gland fistula Definition A disorder characterized N/A
Small intestinal mucositis 1 Asymptomatic or mild symp N/A
Small intestinal mucositis 2 Symptomatic; medical inter N/A
Small intestinal mucositis 3 Severe pain; interfering wiN/A
Small intestinal mucositis 4 Life-threatening consequen N/A
Small intestinal mucositis 5 Death N/A
Small intestinal mucositis Definition A disorder characterized N/A
Small intestinal obstructio1 Asymptomatic; clinical or N/A
Small intestinal obstructio2 Symptomatic; altered GI fuN/A
Small intestinal obstructio3 Hospitalization indicated; N/A
Small intestinal obstructio4 Life-threatening consequen N/A
Small intestinal obstructio5 Death N/A
Small intestinal obstructioDefinition A disorder characterized byN/A
Small intestinal perforatio2 Invasive intervention not N/A
Small intestinal perforatio3 Invasive intervention indi N/A
Small intestinal perforatio4 Life-threatening consequen N/A
Small intestinal perforatio5 Death N/A
Small intestinal perforatioDefinition A disorder characterized byN/A
Small intestinal stenosis 1 Asymptomatic; clinical or N/A
Small intestinal stenosis 2 Symptomatic; altered GI f N/A
Small intestinal stenosis 3 Symptomatic and severelyN/A a
Small intestinal stenosis 4 Life-threatening consequen N/A
Small intestinal stenosis 5 Death N/A
Small intestinal stenosis Definition A disorder characterized bN/A
Small intestine ulcer 1 Asymptomatic; clinical or N/A
Small intestine ulcer 2 Symptomatic; altered GI fuN/A
Small intestine ulcer 3 Severely altered GI functioN/A
Small intestine ulcer 4 Life-threatening consequen N/A
Small intestine ulcer 5 Death N/A
Small intestine ulcer Definition A disorder characterized bN/A
Stomach pain 1 Mild pain N/A
Stomach pain 2 Moderate pain; limiting i N/A
Stomach pain 3 Severe pain; limiting self N/A
Stomach pain Definition A disorder characterized bN/A
Tooth development disord1 Asymptomatic; hypoplasiaN/A
Tooth development disord2 Impairment correctable wiN/A
Tooth development disord3 Maldevelopment with impair N/A
Tooth development disordDefinition A disorder characterized bN/A
Tooth discoloration 1 Surface stains N/A
Tooth discoloration Definition A disorder characterized bN/A
Toothache 1 Mild pain N/A
Toothache 2 Moderate pain; limiting i N/A
Toothache 3 Severe pain; limiting self N/A
Toothache Definition A disorder characterized bN/A
Typhlitis 3 Symptomatic (e.g., abdomin N/A
Typhlitis 4 Life-threatening consequen N/A
Typhlitis 5 Death N/A
Typhlitis Definition A disorder characterized by N/A
Upper gastrointestinal h 1 Mild symptoms; interventiN/A
Upper gastrointestinal h 2 Moderate symptoms; interN/A
Upper gastrointestinal h 3 Transfusion indicated; invaN/A
Upper gastrointestinal h 4 Life-threatening consequen N/A
Upper gastrointestinal h 5 Death N/A
Upper gastrointestinal h Definition A disorder characterized bN/A
Vomiting 1 Intervention not indicatedN/A
Vomiting 2 Outpatient IV hydration; mN/A
Vomiting 3 Tube feeding, TPN, or hospN/A
Vomiting 4 Life-threatening consequeN/A
Vomiting 5 Death N/A
Vomiting Definition A disorder characterized bN/A
Chills 1 Mild sensation of cold; shiN/A
Chills 2 Moderate tremor of the ent N/A
Chills 3 Severe or prolonged, not rN/A
Chills Definition A disorder characterized bN/A
Death neonatal 4 Neonatal loss of life N/A
Death neonatal Definition Newborn death occurring N/A du
Death NOS 5 Death N/A
Death NOS Definition Death that cannot be attr N/A
Edema face 1 Localized facial edema N/A
Edema face 2 Moderate localized facial N/A
Edema face 3 Severe swelling; limiting s N/A
Edema face Definition A disorder characterized by N/A
Edema limbs 1 5 - 10% inter-limb discrep N/A
Edema limbs 2 >10 - 30% inter-limb discr N/A
Edema limbs 3 >30% inter-limb discrepancN/A
Edema limbs Definition A disorder characterized bN/A
Edema trunk 1 Swelling or obscuration ofN/A
Edema trunk 2 Readily apparent obscuratiN/A
Edema trunk 3 Gross deviation from norma N/A
Edema trunk Definition A disorder characterized bN/A
Facial pain 1 Mild pain N/A
Facial pain 2 Moderate pain; limiting i N/A
Facial pain 3 Severe pain; limiting self N/A
Facial pain Definition A disorder characterized bN/A
Fatigue 1 Fatigue relieved by rest N/A
Fatigue 2 Fatigue not relieved by resN/A
Fatigue 3 Fatigue not relieved by resN/A
Fatigue Definition A disorder characterized bN/A
Fever 1 38.0 - 39.0 degrees C (100N/A
Fever 2 >39.0 - 40.0 degrees C (10N/A
Fever 3 >40.0 degrees C (>104.0 deN/A
Fever 4 >40.0 degrees C (>104.0 deN/A
Fever 5 Death N/A
Fever Definition A disorder characterized bN/A
Flu like symptoms 1 Mild flu-like symptoms pr N/A
Flu like symptoms 2 Moderate symptoms; limitN/A
Flu like symptoms 3 Severe symptoms; limitingN/A
Flu like symptoms Definition A disorder characterized byN/A
Gait disturbance 1 Mild change in gait (e.g., N/A
Gait disturbance 2 Moderate change in gait (eN/A
Gait disturbance 3 Limiting self care ADL N/A
Gait disturbance Definition A disorder characterized byN/A
General disorders and admi 1 Asymptomatic or mild sympt N/A
General disorders and admi 2 Moderate; minimal, local oN/A
General disorders and admi 3 Severe or medically signifiN/A
General disorders and admi 4 Life-threatening consequen N/A
General disorders and admi 5 Death N/A
Hypothermia 2 35 - >32 degrees C; 95 - > N/A
Hypothermia 3 32 - >28 degrees C; 89.6 - N/A
Hypothermia 4 <=28 degrees C; 82.4 degreN/A
Hypothermia 5 Death N/A
Hypothermia Definition A disorder characterized N/A
Infusion related reaction 1 Mild transient reaction; inN/A
Infusion related reaction 2 Therapy or infusion interr N/A
Infusion related reaction 3 Prolonged (e.g., not rapid N/A
Infusion related reaction 4 Life-threatening consequen N/A
Infusion related reaction 5 Death N/A
Infusion related reaction Definition A disorder characterized bN/A
Infusion site extravasation2 Erythema with associated N s /A
Infusion site extravasation3 Ulceration or necrosis; se N/A
Infusion site extravasation4 Life-threatening consequen N/A
Infusion site extravasation5 Death N/A
Infusion site extravasationDefinition A disorder characterized bN/A
Injection site reaction 1 Tenderness with or withouN/A
Injection site reaction 2 Pain; lipodystrophy; edema N/A
Injection site reaction 3 Ulceration or necrosis; se N/A
Injection site reaction 4 Life-threatening consequen N/A
Injection site reaction 5 Death N/A
Injection site reaction Definition A disorder characterized bN/A
Irritability 1 Mild; easily consolable N/A
Irritability 2 Moderate; limiting instrumN/A
Irritability 3 Severe abnormal or excessiN/A
Irritability Definition A disorder characterized bN/A
Localized edema 1 Localized to dependent areN/A
Localized edema 2 Moderate localized edemaN/A
Localized edema 3 Severe localized edema and N/A
Localized edema Definition A disorder characterized byN/A
Malaise 1 Uneasiness or lack of well N/A
Malaise 2 Uneasiness or lack of well N/A
Malaise Definition A disorder characterized byN/A
Multi-organ failure 3 Shock with azotemia and ac N/A
Multi-organ failure 4 Life-threatening consequencN/A
Multi-organ failure 5 Death N/A
Multi-organ failure Definition A disorder characterized bN/A
Neck edema 1 Asymptomatic localized n N/A
Neck edema 2 Moderate neck edema; sligN/A
Neck edema 3 Generalized neck edema (e.gN/A
Neck edema Definition A disorder characterized bN/A
Non-cardiac chest pain 1 Mild pain N/A
Non-cardiac chest pain 2 Moderate pain; limiting i N/A
Non-cardiac chest pain 3 Severe pain; limiting self N/A
Non-cardiac chest pain Definition A disorder characterized bN/A
Pain 1 Mild pain N/A
Pain 2 Moderate pain; limiting i N/A
Pain 3 Severe pain; limiting self N/A
Pain Definition A disorder characterized bN/A
Sudden death NOS 5 Death N/A
Sudden death NOS Definition An unexpected death thatN/A
Bile duct stenosis 1 Asymptomatic; clinical or N/A
Bile duct stenosis 2 Symptomatic; altered GI fuN/A
Bile duct stenosis 3 Severely altered GI functioN/A
Bile duct stenosis 4 Life-threatening consequen N/A
Bile duct stenosis 5 Death N/A
Bile duct stenosis Definition A disorder characterized bN/A
Biliary fistula 2 Symptomatic, invasive inteN/A
Biliary fistula 3 Invasive intervention indi N/A
Biliary fistula 4 Life-threatening consequen N/A
Biliary fistula 5 Death N/A
Biliary fistula Definition A disorder characterized N/A
Cholecystitis 2 Symptomatic; medical inteN/A
Cholecystitis 3 Severe symptoms; invasiveN/A
Cholecystitis 4 Life-threatening consequen N/A
Cholecystitis 5 Death N/A
Cholecystitis Definition A disorder characterized bN/A
Gallbladder fistula 1 Asymptomatic N/A
Gallbladder fistula 2 Symptomatic, invasive inteN/A
Gallbladder fistula 3 Invasive intervention indi N/A
Gallbladder fistula 4 Life-threatening consequen N/A
Gallbladder fistula 5 Death N/A
Gallbladder fistula Definition A disorder characterized N/A
Gallbladder necrosis 4 Life-threatening consequen N/A
Gallbladder necrosis 5 Death N/A
Gallbladder necrosis Definition A disorder characterized byN/A
Gallbladder obstruction 1 Asymptomatic; clinical or N/A
Gallbladder obstruction 2 Symptomatic; altered GI fuN/A
Gallbladder obstruction 3 Symptomatic and severelyN/A a
Gallbladder obstruction 4 Life-threatening consequen N/A
Gallbladder obstruction 5 Death N/A
Gallbladder obstruction Definition A disorder characterized bN/A
Gallbladder pain 1 Mild pain N/A
Gallbladder pain 2 Moderate pain; limiting i N/A
Gallbladder pain 3 Severe pain; limiting self N/A
Gallbladder pain Definition A disorder characterized bN/A
Gallbladder perforation 4 Life-threatening consequen N/A
Gallbladder perforation 5 Death N/A
Gallbladder perforation Definition A disorder characterized byN/A
Hepatic failure 3 Asterixis; mild encephalopaN/A
Hepatic failure 4 Life-threatening consequ N/A
Hepatic failure 5 Death N/A
Hepatic failure Definition A disorder characterized bN/A
Hepatic hemorrhage 1 Mild symptoms; interventiN/A
Hepatic hemorrhage 2 Moderate symptoms; interN/A
Hepatic hemorrhage 3 Transfusion indicated; invaN/A
Hepatic hemorrhage 4 Life-threatening consequen N/A
Hepatic hemorrhage 5 Death N/A
Hepatic hemorrhage Definition A disorder characterized bN/A
Hepatic necrosis 4 Life-threatening consequen N/A
Hepatic necrosis 5 Death N/A
Hepatic necrosis Definition A disorder characterized bN/A
Hepatic pain 1 Mild pain N/A
Hepatic pain 2 Moderate pain; limiting i N/A
Hepatic pain 3 Severe pain; limiting self N/A
Hepatic pain Definition A disorder characterized bN/A
Hepatobiliary disorders - O1 Asymptomatic or mild sympt N/A
Hepatobiliary disorders - O2 Moderate; minimal, local oN/A
Hepatobiliary disorders - O3 Severe or medically signifiN/A
Hepatobiliary disorders - O4 Life-threatening consequen N/A
Hepatobiliary disorders - O5 Death N/A
Perforation bile duct 3 Invasive intervention indi N/A
Perforation bile duct 4 Life-threatening consequen N/A
Perforation bile duct 5 Death N/A
Perforation bile duct Definition A disorder characterized by N/A
Portal hypertension 2 Decreased portal vein flo N/A
Portal hypertension 3 Reversal/retrograde portalN/A
Portal hypertension 4 Life-threatening consequen N/A
Portal hypertension 5 Death N/A
Portal hypertension Definition A disorder characterized bN/A
Portal vein thrombosis 2 Intervention not indicatedN/A
Portal vein thrombosis 3 Medical intervention indi N/A
Portal vein thrombosis 4 Life-threatening consequen N/A
Portal vein thrombosis 5 Death N/A
Portal vein thrombosis Definition A disorder characterized bN/A
Allergic reaction 1 Systemic intervention not N/A
Allergic reaction 2 Oral intervention indicate N/A
Allergic reaction 3 Bronchospasm; hospitalizat N/A
Allergic reaction 4 Life-threatening consequen N/A
Allergic reaction 5 Death N/A
Allergic reaction Definition A disorder characterized bN/A
Anaphylaxis 3 Symptomatic bronchospasm, N/A
Anaphylaxis 4 Life-threatening consequen N/A
Anaphylaxis 5 Death N/A
Anaphylaxis Definition A disorder characterized bN/A
Autoimmune disorder 1 Asymptomatic; serologic oN/A
Autoimmune disorder 2 Evidence of autoimmune rea N/A
Autoimmune disorder 3 Autoimmune reactions invol N/A
Autoimmune disorder 4 Life-threatening consequen N/A
Autoimmune disorder 5 Death N/A
Autoimmune disorder Definition A disorder characterized bN/A
Cytokine release syndrom1 Fever with or without conN/A
Cytokine release syndrom2 Hypotension responding toN/A
Cytokine release syndrom3 Hypotension managed with N/A
Cytokine release syndrom4 Life-threatening consequen N/A
Cytokine release syndrom5 Death N/A
Cytokine release syndromDefinition A disorder characterized bN/A
Immune system disorders 1- Asymptomatic or mild sympt N/A
Immune system disorders 2- Moderate; minimal, local oN/A
Immune system disorders 3- Severe or medically signifiN/A
Immune system disorders 4- Life-threatening consequen N/A
Immune system disorders 5- Death N/A
Serum sickness 1 Asymptomatic; clinical or N/A
Serum sickness 2 Moderate arthralgia; fever,N/A
Serum sickness 3 Severe arthralgia or arthritN/A
Serum sickness 4 Life-threatening consequen N/A
Serum sickness 5 Death N/A
Serum sickness Definition A disorder characterized bN/A
Abdominal infection 3 IV antibiotic, antifungal, o N/A
Abdominal infection 4 Life-threatening consequen N/A
Abdominal infection 5 Death N/A
Abdominal infection Definition A disorder characterized bN/A
Anorectal infection 1 Localized, local interventi N/A
Anorectal infection 2 Oral intervention indicatedN/A
Anorectal infection 3 IV antibiotic, antifungal, o N/A
Anorectal infection 4 Life-threatening consequen N/A
Anorectal infection 5 Death N/A
Anorectal infection Definition A disorder characterized bN/A
Appendicitis 3 IV antibiotic, antifungal, o N/A
Appendicitis 4 Life-threatening consequen N/A
Appendicitis 5 Death N/A
Appendicitis Definition A disorder characterized N/A
Appendicitis perforated 3 Medical intervention indicN/A
Appendicitis perforated 4 Life-threatening consequen N/A
Appendicitis perforated 5 Death N/A
Appendicitis perforated Definition A disorder characterized N/A
Infections and infestations2 Moderate; minimal, local oAppendicitis perforated
Arteritis infective 3 IV antibiotic, antifungal, o N/A
Arteritis infective 4 Life-threatening consequen N/A
Arteritis infective 5 Death N/A
Arteritis infective Definition A disorder characterized by N/A
Biliary tract infection 3 IV antibiotic, antifungal, o N/A
Biliary tract infection 4 Life-threatening consequen N/A
Biliary tract infection 5 Death N/A
Biliary tract infection Definition A disorder characterized by N/A
Bladder infection 2 Oral intervention indicatedN/A
Bladder infection 3 IV antibiotic, antifungal, o N/A
Bladder infection 4 Life-threatening consequen N/A
Bladder infection 5 Death N/A
Bladder infection Definition A disorder characterized bN/A
Bone infection 3 IV antibiotic, antifungal, o N/A
Bone infection 4 Life-threatening consequen N/A
Bone infection 5 Death N/A
Bone infection Definition A disorder characterized bN/A
Breast infection 2 Local infection with modera N/A
Breast infection 3 IV antibiotic, antifungal, o N/A
Breast infection 4 Life-threatening consequen N/A
Breast infection 5 Death N/A
Breast infection Definition A disorder characterized bN/A
Bronchial infection 2 Moderate symptoms; oralN/A int
Bronchial infection 3 IV antibiotic, antifungal, o N/A
Bronchial infection 4 Life-threatening consequen N/A
Bronchial infection 5 Death N/A
Bronchial infection Definition A disorder characterized bN/A
Catheter related infection2 Localized; local interventioN/A
Catheter related infection3 IV antibiotic, antifungal, o N/A
Catheter related infection4 Life-threatening consequen N/A
Catheter related infection5 Death N/A
Catheter related infectionDefinition A disorder characterized bN/A
Cecal infection 3 IV antibiotic, antifungal, o N/A
Cecal infection 4 Life-threatening consequen N/A
Cecal infection 5 Death N/A
Cecal infection Definition A disorder characterized bN/A
Cervicitis infection 2 Localized; local interventioN/A
Cervicitis infection 3 IV antibiotic, antifungal, o N/A
Cervicitis infection 4 Life-threatening consequen N/A
Cervicitis infection 5 Death N/A
Cervicitis infection Definition A disorder characterized by N/A
Infections and infestations5 Death Conjunctivitis infective
Conjunctivitis infective 2 Localized; local interventioN/A
Conjunctivitis infective 3 IV antibiotic, antifungal, o N/A
Conjunctivitis infective 4 Life-threatening consequen N/A
Conjunctivitis infective Definition A disorder characterized by N/A
Corneal infection 2 Localized; local interventioN/A
Corneal infection 3 IV antibiotic, antifungal, o N/A
Corneal infection 4 Life-threatening consequen N/A
Corneal infection 5 Death N/A
Corneal infection Definition A disorder characterized bN/A
Cranial nerve infection 3 IV antibiotic, antifungal, o N/A
Cranial nerve infection 4 Life-threatening consequen N/A
Cranial nerve infection 5 Death N/A
Cranial nerve infection Definition A disorder characterized by N/A
Device related infection 3 IV antibiotic, antifungal, o N/A
Device related infection 4 Life-threatening consequen N/A
Device related infection 5 Death N/A
Device related infection Definition A disorder characterized bN/A
Duodenal infection 2 Moderate symptoms; medical N/A
Duodenal infection 3 IV antibiotic, antifungal, o N/A
Duodenal infection 4 Life-threatening consequen N/A
Duodenal infection 5 Death N/A
Duodenal infection Definition A disorder characterized bN/A
Encephalitis infection 3 IV antibiotic, antifungal, N/A
Encephalitis infection 4 Life-threatening consequen N/A
Encephalitis infection 5 Death N/A
Encephalitis infection Definition A disorder characterized by N/A
Encephalomyelitis infectio3 IV antibiotic, antifungal, o N/A
Encephalomyelitis infectio4 Life-threatening consequen N/A
Encephalomyelitis infectio5 Death N/A
Encephalomyelitis infectioDefinition A disorder characterized by N/A
Endocarditis infective 3 IV antibiotic, antifungal, o N/A
Endocarditis infective 4 Life-threatening consequen N/A
Endocarditis infective 5 Death N/A
Endocarditis infective Definition A disorder characterized by N/A
Endophthalmitis 2 Local intervention indicat N/A
Endophthalmitis 3 Systemic intervention; hosN/A
Endophthalmitis 4 Best corrected visual acui N/A
Endophthalmitis Definition A disorder characterized by N/A
Enterocolitis infectious 2 Passage of >3 unformed stoo N/A
Enterocolitis infectious 3 IV antibiotic, antifungal, N/A
Enterocolitis infectious 4 Life-threatening consequen N/A
Enterocolitis infectious 5 Death N/A
Enterocolitis infectious Definition A disorder characterized by N/A
Esophageal infection 2 Local intervention indicated N/A
Esophageal infection 3 IV antibiotic, antifungal, o N/A
Esophageal infection 4 Life-threatening consequen N/A
Esophageal infection 5 Death N/A
Esophageal infection Definition A disorder characterized bN/A
Eye infection 2 Localized; local interventioN/A
Eye infection 3 IV antibiotic, antifungal, o N/A
Eye infection 4 Life-threatening consequen N/A
Eye infection 5 Death N/A
Eye infection Definition A disorder characterized bN/A
Gallbladder infection 3 IV antibiotic, antifungal, o N/A
Gallbladder infection 4 Life-threatening consequen N/A
Gallbladder infection 5 Death N/A
Gallbladder infection Definition A disorder characterized by N/A
Gum infection 1 Local therapy indicated (s N/A
Gum infection 2 Moderate symptoms; oralN/A int
Gum infection 3 IV antibiotic, antifungal, o N/A
Gum infection 4 Life-threatening consequen N/A
Gum infection 5 Death N/A
Gum infection Definition A disorder characterized bN/A
Hepatic infection 3 IV antibiotic, antifungal, o N/A
Hepatic infection 4 Life-threatening consequen N/A
Hepatic infection 5 Death N/A
Hepatic infection Definition A disorder characterized by N/A
Hepatitis viral 1 Asymptomatic, interventioN/A
Hepatitis viral 3 Symptomatic liver dysfuncti N/A
Hepatitis viral 4 Life-threatening consequeN/A
Hepatitis viral 5 Death N/A
Hepatitis viral Definition A disorder characterized bN/A
Infections and infestations1 Asymptomatic or mild sympt N/A
Infections and infestations2 Moderate; minimal, local oN/A
Infections and infestations3 Severe or medically signifiN/A
Infections and infestations4 Life-threatening consequen N/A
Infections and infestations5 Death N/A
Infective myositis 2 Localized; local interventioN/A
Infective myositis 3 IV antibiotic, antifungal, o N/A
Infective myositis 4 Life-threatening consequen N/A
Infective myositis 5 Death N/A
Infective myositis Definition A disorder characterized bN/A
Joint infection 2 Localized; local interventioN/A
Joint infection 3 Arthroscopic intervention N i /A
Joint infection 4 Life-threatening consequen N/A
Joint infection 5 Death N/A
Joint infection Definition A disorder characterized by N/A
Kidney infection 3 IV antibiotic, antifungal, o N/A
Kidney infection 4 Life-threatening consequen N/A
Kidney infection 5 Death N/A
Kidney infection Definition A disorder characterized bN/A
Laryngitis 2 Moderate symptoms; oralN/A int
Laryngitis 3 IV antibiotic, antifungal, o N/A
Laryngitis 4 Life-threatening consequen N/A
Laryngitis 5 Death N/A
Laryngitis Definition A disorder characterized bN/A
Lip infection 1 Localized, local interventi N/A
Lip infection 2 Oral intervention indicatedN/A
Lip infection 3 IV antibiotic, antifungal, o N/A
Lip infection Definition A disorder characterized by N/A
Lung infection 2 Moderate symptoms; oralN/A int
Lung infection 3 IV antibiotic, antifungal, o N/A
Lung infection 4 Life-threatening consequen N/A
Lung infection 5 Death N/A
Lung infection Definition A disorder characterized bN/A
Lymph gland infection 2 Localized; oral interventionN/A
Lymph gland infection 3 IV antibiotic, antifungal, o N/A
Lymph gland infection 4 Life-threatening consequen N/A
Lymph gland infection 5 Death N/A
Lymph gland infection Definition A disorder characterized bN/A
Mediastinal infection 3 IV antibiotic, antifungal, o N/A
Mediastinal infection 4 Life-threatening consequen N/A
Mediastinal infection 5 Death N/A
Mediastinal infection Definition A disorder characterized bN/A
Meningitis 3 IV antibiotic, antifungal, o N/A
Meningitis 4 Life-threatening consequen N/A
Meningitis 5 Death N/A
Meningitis Definition A disorder characterized bN/A
Mucosal infection 1 Localized, local interventi N/A
Mucosal infection 2 Oral intervention indicatedN/A
Mucosal infection 3 IV antibiotic, antifungal, o N/A
Mucosal infection 4 Life-threatening consequen N/A
Mucosal infection 5 Death N/A
Mucosal infection Definition A disorder characterized bN/A
Nail infection 1 Localized, local interventi N/A
Nail infection 2 Oral intervention indicatedN/A
Nail infection 3 IV antibiotic, antifungal, o N/A
Nail infection Definition A disorder characterized by N/A
Otitis externa 1 Local intervention indicated N/A
Otitis externa 3 IV antibiotic, antifungal, o N/A
Otitis externa 4 Life-threatening consequen N/A
Otitis externa 5 Death N/A
Otitis externa Definition A disorder characterized bN/A
Otitis media 2 Localized; oral interventionN/A
Otitis media 3 IV antibiotic, antifungal, o N/A
Otitis media 4 Life-threatening consequen N/A
Otitis media 5 Death N/A
Otitis media Definition A disorder characterized bN/A
Ovarian infection 2 Localized; oral interventionN/A
Ovarian infection 3 IV antibiotic, antifungal, o N/A
Ovarian infection 4 Life-threatening consequen N/A
Ovarian infection 5 Death N/A
Ovarian infection Definition A disorder characterized bN/A
Pancreas infection 3 IV antibiotic, antifungal, o N/A
Pancreas infection 4 Life-threatening consequen N/A
Pancreas infection 5 Death N/A
Pancreas infection Definition A disorder characterized bN/A
Papulopustular rash 1 Papules and/or pustules c N/A
Papulopustular rash 2 Papules and/or pustules c N/A
Papulopustular rash 3 Papules and/or pustules coN/A
Papulopustular rash 4 Life-threatening consequeN/A
Papulopustular rash 5 Death N/A
Papulopustular rash Definition A disorder characterized by N/A
Paronychia 1 Nail fold edema or erythem N/A
Paronychia 2 Local intervention indicateN/A
Paronychia 3 Operative intervention indiN/A
Paronychia Definition A disorder characterized by N/A
Pelvic infection 2 Moderate symptoms; oralN/A int
Pelvic infection 3 IV antibiotic, antifungal, o N/A
Pelvic infection 4 Life-threatening consequen N/A
Pelvic infection 5 Death N/A
Pelvic infection Definition A disorder characterized by N/A
Penile infection 1 Local intervention indicated N/A
Penile infection 3 IV antibiotic, antifungal, o N/A
Penile infection 4 Life-threatening consequen N/A
Penile infection 5 Death N/A
Penile infection Definition A disorder characterized bN/A
Periorbital infection 2 Localized; local interventioN/A
Periorbital infection 3 IV antibiotic, antifungal, o N/A
Periorbital infection 4 Life-threatening consequen N/A
Periorbital infection 5 Death N/A
Periorbital infection Definition A disorder characterized by N/A
Peripheral nerve infection2 Localized; local interventioN/A
Peripheral nerve infection3 IV antibiotic, antifungal, o N/A
Peripheral nerve infection4 Life-threatening consequen N/A
Peripheral nerve infection5 Death N/A
Peripheral nerve infectionDefinition A disorder characterized bN/A
Peritoneal infection 3 IV antibiotic, antifungal, o N/A
Peritoneal infection 4 Life-threatening consequen N/A
Peritoneal infection 5 Death N/A
Peritoneal infection Definition A disorder characterized bN/A
Pharyngitis 2 Oral intervention indicatedN/A
Pharyngitis 3 IV antibiotic, antifungal, o N/A
Pharyngitis 4 Life-threatening consequen N/A
Pharyngitis 5 Death N/A
Pharyngitis Definition A disorder characterized bN/A
Phlebitis infective 1 Local intervention indicated N/A
Phlebitis infective 3 IV antibiotic, antifungal, o N/A
Phlebitis infective 4 Life-threatening consequen N/A
Phlebitis infective 5 Death N/A
Phlebitis infective Definition A disorder characterized bN/A
Pleural infection 2 Oral intervention indicatedN/A
Pleural infection 3 IV antibiotic, antifungal, o N/A
Pleural infection 4 Life-threatening consequen N/A
Pleural infection 5 Death N/A
Pleural infection Definition A disorder characterized bN/A
Prostate infection 2 Moderate symptoms; oralN/A int
Prostate infection 3 IV antibiotic, antifungal, o N/A
Prostate infection 4 Life-threatening consequen N/A
Prostate infection 5 Death N/A
Prostate infection Definition A disorder characterized bN/A
Rash pustular 2 Localized; local interventioN/A
Rash pustular 3 IV antibiotic, antifungal, o N/A
Rash pustular Definition A disorder characterized by N/A
Rhinitis infective 2 Localized; local interventionN/A
indicated
Rhinitis infective Definition A disorder characterized bN/A
Salivary gland infection 2 Moderate symptoms; oralN/A int
Salivary gland infection 3 IV antibiotic, antifungal, o N/A
Salivary gland infection 4 Life-threatening consequen N/A
Salivary gland infection 5 Death N/A
Salivary gland infection Definition A disorder characterized by N/A
Scrotal infection 1 Local intervention indicated N/A
Scrotal infection 3 IV antibiotic, antifungal, o N/A
Scrotal infection 4 Life-threatening consequen N/A
Scrotal infection 5 Death N/A
Scrotal infection Definition A disorder characterized bN/A
Sepsis 4 Life-threatening consequen N/A
Sepsis 5 Death N/A
Sepsis Definition A disorder characterized bN/A
Sinusitis 2 Localized; oral interventionN/A
Sinusitis 3 IV antibiotic, antifungal, o N/A
Sinusitis 4 Life-threatening consequen N/A
Sinusitis 5 Death N/A
Sinusitis Definition A disorder characterized N/A
Skin infection 1 Localized, local interventi N/A
Skin infection 2 Oral intervention indicatedN/A
Skin infection 3 IV antibiotic, antifungal, o N/A
Skin infection 4 Life-threatening consequen N/A
Skin infection 5 Death N/A
Skin infection Definition A disorder characterized by N/A
Small intestine infection 2 Moderate symptoms; oralN/A int
Small intestine infection 3 IV antibiotic, antifungal, o N/A
Small intestine infection 4 Life-threatening consequen N/A
Small intestine infection 5 Death N/A
Small intestine infection Definition A disorder characterized by N/A
Soft tissue infection 2 Localized; oral interventionN/A
Soft tissue infection 3 IV antibiotic, antifungal, o N/A
Soft tissue infection 4 Life-threatening consequen N/A
Soft tissue infection 5 Death N/A
Soft tissue infection Definition A disorder characterized by N/A
Splenic infection 3 IV antibiotic, antifungal, o N/A
Splenic infection 4 Life-threatening consequen N/A
Splenic infection 5 Death N/A
Splenic infection Definition A disorder characterized bN/A
Stoma site infection 1 Localized, local interventi N/A
Stoma site infection 2 Oral intervention indicatedN/A
Stoma site infection 3 IV antibiotic, antifungal, o N/A
Stoma site infection 4 Life-threatening consequen N/A
Stoma site infection 5 Death N/A
Stoma site infection Definition A disorder characterized bN/A
Tooth infection 2 Localized; local interventioN/A
Tooth infection 3 IV antibiotic, antifungal, o N/A
Tooth infection 4 Life-threatening consequen N/A
Tooth infection 5 Death N/A
Tooth infection Definition A disorder characterized bN/A
Tracheitis 2 Moderate symptoms; oralN/A int
Tracheitis 3 IV antibiotic, antifungal, o N/A
Tracheitis 4 Life-threatening consequen N/A
Tracheitis 5 Death N/A
Tracheitis Definition A disorder characterized bN/A
Upper respiratory infectio2 Moderate symptoms; oralN/A int
Upper respiratory infectio3 IV antibiotic, antifungal, o N/A
Upper respiratory infectio4 Life-threatening consequen N/A
Upper respiratory infectio5 Death N/A
Upper respiratory infectioDefinition A disorder characterized by N/A
Urethral infection 2 Localized; oral interventionN/A
Urethral infection 3 IV antibiotic, antifungal, o N/A
Urethral infection 4 Life-threatening consequen N/A
Urethral infection 5 Death N/A
Urethral infection Definition A disorder characterized bN/A
Urinary tract infection 2 Localized; oral interventionN/A
Urinary tract infection 3 IV antibiotic, antifungal, o N/A
Urinary tract infection 4 Life-threatening consequen N/A
Urinary tract infection 5 Death N/A
Urinary tract infection Definition A disorder characterized bN/A
Uterine infection 2 Moderate symptoms; oralN/A int
Uterine infection 3 IV antibiotic, antifungal, o N/A
Uterine infection 4 Life-threatening consequen N/A
Uterine infection 5 Death N/A
Uterine infection Definition A disorder characterized N/A
Vaginal infection 1 Local intervention indicated N/A
Vaginal infection 3 IV antibiotic, antifungal, o N/A
Vaginal infection 4 Life-threatening consequen N/A
Vaginal infection 5 Death N/A
Vaginal infection Definition A disorder characterized bN/A
Vulval infection 1 Localized, local interventi N/A
Vulval infection 2 Oral intervention indicatedN/A
Vulval infection 3 IV antibiotic, antifungal, o N/A
Vulval infection 4 Life-threatening consequen N/A
Vulval infection 5 Death N/A
Vulval infection Definition A disorder characterized by N/A
Wound infection 1 Local intervention indicated N/A
Wound infection 3 IV antibiotic, antifungal, o N/A
Wound infection 4 Life-threatening consequen N/A
Wound infection 5 Death N/A
Wound infection Definition A disorder characterized bN/A
Ankle fracture 1 Mild; non-operative intervN/A
Ankle fracture 2 Limiting instrumental ADL;N/A
Ankle fracture 3 Limiting self care ADL; ele N/A
Ankle fracture Definition A finding of damage to theN/A
Aortic injury 3 Severe symptoms; limitingN/A
Aortic injury 4 Life-threatening consequeN/A
Aortic injury 5 Death N/A
Aortic injury Definition A finding of damage to theN/A
Arterial injury 1 Asymptomatic diagnostic fiN/A
Arterial injury 2 Symptomatic; repair or revN/A
Arterial injury 3 Severe symptoms; limitingN/A
Arterial injury 4 Life-threatening consequeN/A
Arterial injury 5 Death N/A
Arterial injury Definition A finding of damage to an N/A
Biliary anastomotic leak 1 Asymptomatic diagnostic fiN/A
Biliary anastomotic leak 2 Symptomatic; medical inteN/A
Biliary anastomotic leak 3 Severe symptoms; invasiveN/A
Biliary anastomotic leak 4 Life-threatening consequen N/A
Biliary anastomotic leak 5 Death N/A
Biliary anastomotic leak Definition A finding of leakage of bi N/A
Bladder anastomotic leak 1 Asymptomatic diagnostic fiN/A
Bladder anastomotic leak 2 Symptomatic; medical inteN/A
Bladder anastomotic leak 3 Severe symptoms; invasiveN/A
Bladder anastomotic leak 4 Life-threatening consequen N/A
Bladder anastomotic leak 5 Death N/A
Bladder anastomotic leak Definition A finding of leakage of ur N/A
Bruising 1 Localized or in a dependenN/A
Bruising 2 Generalized N/A
Bruising Definition A finding of injury of the N/A
Burn 1 Minimal symptoms; interve N/A
Burn 2 Medical intervention; minN/A
Burn 3 Moderate to major debride N/A
Burn 4 Life-threatening consequeN/A
Burn 5 Death N/A
Burn Definition A finding of impaired inte N/A
Dermatitis radiation 1 Faint erythema or dry de N/A
Dermatitis radiation 2 Moderate to brisk erythemN/A
Dermatitis radiation 3 Moist desquamation in areN/A
Dermatitis radiation 4 Life-threatening consequen N/A
Dermatitis radiation 5 Death N/A
Dermatitis radiation Definition A finding of cutaneous inflN/A
Esophageal anastomotic l 1 Asymptomatic diagnostic fiN/A
Esophageal anastomotic l 2 Symptomatic; medical inteN/A
Esophageal anastomotic l 3 Severe symptoms; invasiveN/A
Esophageal anastomotic l 4 Life-threatening consequen N/A
Esophageal anastomotic l 5 Death N/A
Esophageal anastomotic l Definition A finding of leakage due N/A
Fall 1 Minor with no resultant inN/A
Fall 2 Symptomatic; noninvasiveN/A
Fall 3 Hospitalization indicated; N/A
Fall Definition A finding of sudden movem N/A
Fallopian tube anastomoti1 Asymptomatic; clinical or N/A
Fallopian tube anastomoti2 Symptomatic; medical inteN/A
Fallopian tube anastomoti3 Severe symptoms; invasiveN/A
Fallopian tube anastomoti4 Life-threatening consequen N/A
Fallopian tube anastomoti5 Death N/A
Fallopian tube anastomotiDefinition A finding of leakage due t N/A
Injury, poisoning and proc1 Asymptomatic or mild sympt Fallopian tube perforation
Fallopian tube perforation2 Invasive intervention not N/A
Fallopian tube perforation3 Invasive intervention indi N/A
Fallopian tube perforation4 Life-threatening consequen N/A
Fallopian tube perforation5 Death N/A
Fallopian tube perforationDefinition A disorder characterized by N/A
Fracture 1 Asymptomatic; clinical or N/A
Fracture 2 Symptomatic but non-displN/A
Fracture 3 Severe symptoms; displaceN/A
Fracture 4 Life-threatening consequen N/A
Fracture 5 Death N/A
Fracture Definition A finding of traumatic injuN/A
Gastric anastomotic leak 1 Asymptomatic diagnostic fiN/A
Gastric anastomotic leak 2 Symptomatic; medical inteN/A
Gastric anastomotic leak 3 Severe symptoms; invasiveN/A
Gastric anastomotic leak 4 Life-threatening consequen N/A
Gastric anastomotic leak 5 Death N/A
Gastric anastomotic leak Definition A finding of leakage due t N/A
Gastrointestinal anastomot1 Asymptomatic diagnostic fiN/A
Gastrointestinal anastomot2 Symptomatic; medical inteN/A
Gastrointestinal anastomot3 Severe symptoms; invasiveN/A
Gastrointestinal anastomot4 Life-threatening consequen N/A
Gastrointestinal anastomot5 Death N/A
Gastrointestinal anastomotDefinition A finding of leakage due t N/A
Gastrointestinal stoma nec2 Superficial necrosis; inter N/A
Gastrointestinal stoma nec3 Severe symptoms; hospitali N/A
Gastrointestinal stoma nec4 Life-threatening consequen N/A
Gastrointestinal stoma nec5 Death N/A
Gastrointestinal stoma necDefinition A disorder characterized by N/A
Hip fracture 2 Hairline fracture; mild pa N/A
Hip fracture 3 Severe pain; hospitalizatioN/A
Hip fracture 4 Life-threatening consequ N/A
Hip fracture Definition A finding of traumatic injuN/A
Injury to carotid artery 3 Severe symptoms; limitingN/A s
Injury to carotid artery 4 Life-threatening consequen N/A
Injury to carotid artery 5 Death N/A
Injury to carotid artery Definition A finding of damage to theN/A
Injury to inferior vena cav 4 Life-threatening consequen N/A
Injury to inferior vena cav 5 Death N/A
Injury to inferior vena cav Definition A finding of damage to theN/A
Injury to jugular vein 3 Symptomatic limiting self cN/A
Injury to jugular vein 4 Life-threatening consequen N/A
Injury to jugular vein 5 Death N/A
Injury to jugular vein Definition A finding of damage to theN/A
Injury to superior vena ca 1 Asymptomatic diagnostic fiN/A
Injury to superior vena ca 2 Symptomatic; repair or revN/A
Injury to superior vena ca 3 Severe symptoms; limitingN/A
Injury to superior vena ca 4 Life-threatening consequen N/A
Injury to superior vena ca 5 Death N/A
Injury to superior vena ca Definition A finding of damage to theN/A
Injury, poisoning and proc1 Asymptomatic or mild sympt N/A
Injury, poisoning and proc2 Moderate; minimal, local oN/A
Injury, poisoning and proc3 Severe or medically signifiN/A
Injury, poisoning and proc4 Life-threatening consequen N/A
Injury, poisoning and proc5 Death N/A
Intestinal stoma leak 1 Asymptomatic diagnostic fiN/A
Intestinal stoma leak 2 Symptomatic; medical inteN/A
Intestinal stoma leak 3 Severe symptoms; invasiveN/A
Intestinal stoma leak 4 Life-threatening consequen N/A
Intestinal stoma leak 5 Death N/A
Intestinal stoma leak Definition A finding of leakage of co N/A
Intestinal stoma obstructi 2 Self-limited; intervention N/A
Intestinal stoma obstructi 3 Severe symptoms; IV fluidsN/A
Intestinal stoma obstructi 4 Life-threatening consequen N/A
Intestinal stoma obstructi 5 Death N/A
Intestinal stoma obstructi Definition A disorder characterized bN/A
Intestinal stoma site bleed1 Minimal bleeding identifieN/A
Intestinal stoma site bleed2 Moderate bleeding; medica N/A
Intestinal stoma site bleed3 Transfusion indicated; inv N/A
Intestinal stoma site bleed4 Life-threatening consequen N/A
Intestinal stoma site bleed5 Death N/A
Intestinal stoma site bleedDefinition A disorder characterized bN/A
Intraoperative arterial inju1 Primary repair of injured N/A
Intraoperative arterial inju2 Partial resection of injure N/A
Intraoperative arterial inju3 Complete resection or recoN/A
Intraoperative arterial inju4 Life-threatening consequen N/A
Intraoperative arterial inju5 Death N/A
Intraoperative arterial injuDefinition A finding of damage to an N/A
Intraoperative breast injur1 Primary repair of injured N/A
Intraoperative breast injur2 Partial resection of injure N/A
Intraoperative breast injur3 Complete resection or recoN/A
Intraoperative breast injur4 Life-threatening consequen N/A
Intraoperative breast injur5 Death N/A
Intraoperative breast injurDefinition A finding of damage to th N/A
Intraoperative cardiac inju3 Primary repair of injured N/A
Intraoperative cardiac inju4 Life-threatening consequen N/A
Intraoperative cardiac inju5 Death N/A
Intraoperative cardiac injuDefinition A finding of damage to theN/A
Intraoperative ear injury 1 Primary repair of injured N/A
Intraoperative ear injury 2 Partial resection of injure N/A
Intraoperative ear injury 3 Complete resection or recoN/A
Intraoperative ear injury 4 Life-threatening consequen N/A
Intraoperative ear injury 5 Death N/A
Intraoperative ear injury Definition A finding of damage to theN/A
Intraoperative endocrine i1 Primary repair of injured N/A
Intraoperative endocrine i2 Partial resection of injure N/A
Intraoperative endocrine i3 Complete resection or recoN/A
Intraoperative endocrine i4 Life-threatening consequen N/A
Intraoperative endocrine i5 Death N/A
Intraoperative endocrine iDefinition A finding of damage to theN/A
Intraoperative gastrointest1 Primary repair of injured N/A
Intraoperative gastrointest2 Partial resection of injure N/A
Intraoperative gastrointest3 Complete resection or recoN/A
Intraoperative gastrointest4 Life-threatening consequen N/A
Intraoperative gastrointest5 Death N/A
Intraoperative gastrointestDefinition A finding of damage to theN/A
Intraoperative head and ne1 Primary repair of injured N/A
Intraoperative head and ne2 Partial resection of injure N/A
Intraoperative head and ne3 Complete resection or recoN/A
Intraoperative head and ne4 Life-threatening consequen N/A
Intraoperative head and ne5 Death N/A
Intraoperative head and neDefinition A finding of damage to theN/A
Intraoperative hemorrhag3 Postoperative invasive int N/A
Intraoperative hemorrhag4 Life-threatening consequen N/A
Intraoperative hemorrhag5 Death N/A
Intraoperative hemorrhagDefinition A finding of uncontrolled N/A
Intraoperative hepatobiliar1 Primary repair of injured N/A
Intraoperative hepatobiliar2 Partial resection of injure N/A
Intraoperative hepatobiliar3 Complete resection or recoN/A
Intraoperative hepatobiliar4 Life-threatening consequen N/A
Intraoperative hepatobiliar5 Death N/A
Intraoperative hepatobiliarDefinition A finding of damage to theN/A
Intraoperative musculoskel1 Primary repair of injured N/A
Intraoperative musculoskel2 Partial resection of injure N/A
Intraoperative musculoskel3 Complete resection or recoN/A
Intraoperative musculoskel4 Life-threatening consequen N/A
Intraoperative musculoskel5 Death N/A
Intraoperative musculoskelDefinition A finding of damage to theN/A
Intraoperative neurological1 Primary repair of injured N/A
Intraoperative neurological2 Partial resection of injure N/A
Intraoperative neurological3 Complete resection or recoN/A
Intraoperative neurological4 Life-threatening consequen N/A
Intraoperative neurological5 Death N/A
Intraoperative neurologicalDefinition A finding of damage to theN/A
Intraoperative ocular injur1 Primary repair of injured N/A
Intraoperative ocular injur2 Partial resection of injure N/A
Intraoperative ocular injur3 Complete resection or recoN/A
Intraoperative ocular injur4 Life-threatening consequen N/A
Intraoperative ocular injur5 Death N/A
Intraoperative ocular injurDefinition A finding of damage to theN/A
Intraoperative renal injury1 Primary repair of injured N/A
Intraoperative renal injury2 Partial resection of injure N/A
Intraoperative renal injury3 Complete resection or recoN/A
Intraoperative renal injury4 Life-threatening consequen N/A
Intraoperative renal injury5 Death N/A
Intraoperative renal injuryDefinition A finding of damage to theN/A
Intraoperative reproductive1 Primary repair of injured N/A
Intraoperative reproductive2 Partial resection of injure N/A
Intraoperative reproductive3 Complete resection or recoN/A
Intraoperative reproductive4 Life-threatening consequen N/A
Intraoperative reproductive5 Death N/A
Intraoperative reproductiveDefinition A finding of damage to theN/A
Intraoperative respiratory 1 Primary repair of injured N/A
Intraoperative respiratory 2 Partial resection of injure N/A
Intraoperative respiratory 3 Complete resection or recoN/A
Intraoperative respiratory 4 Life-threatening consequen N/A
Intraoperative respiratory 5 Death N/A
Intraoperative respiratory Definition A finding of damage to theN/A
Injury, poisoning and proc1 Asymptomatic or mild sympt Intraoperative skin injury
Injury, poisoning and proc2 Moderate; minimal, local oIntraoperative skin injury
Injury, poisoning and proc3 Severe or medically signifiIntraoperative skin injury
Injury, poisoning and proc4 Life-threatening consequen Intraoperative skin injury
Injury, poisoning and proc5 Death Intraoperative skin injury
Injury, poisoning and procDefinition - N/A
Intraoperative splenic inju2 Primary repair of injured N/A
Intraoperative splenic inju3 Resection or reconstruction N/A
Intraoperative splenic inju4 Life-threatening consequen N/A
Intraoperative splenic inju5 Death N/A
Intraoperative splenic injuDefinition A finding of damage to theN/A
Intraoperative urinary inju1 Primary repair of injured N/A
Intraoperative urinary inju2 Partial resection of injure N/A
Intraoperative urinary inju3 Complete resection or recoN/A
Intraoperative urinary inju4 Life-threatening consequen N/A
Intraoperative urinary inju5 Death N/A
Intraoperative urinary injuDefinition A finding of damage to theN/A
Intraoperative venous inju1 Primary repair of injured N/A
Intraoperative venous inju2 Partial resection of injure N/A
Intraoperative venous inju3 Complete resection or recoN/A
Intraoperative venous inju4 Life-threatening consequen N/A
Intraoperative venous inju5 Death N/A
Intraoperative venous injuDefinition A finding of damage to a vN/A
Kidney anastomotic leak 1 Asymptomatic diagnostic fiN/A
Kidney anastomotic leak 2 Symptomatic; medical inteN/A
Kidney anastomotic leak 3 Severe symptoms; invasiveN/A
Kidney anastomotic leak 4 Life-threatening consequen N/A
Kidney anastomotic leak 5 Death N/A
Kidney anastomotic leak Definition A finding of leakage of ur N/A
Large intestinal anastomot1 Asymptomatic diagnostic fiN/A
Large intestinal anastomot2 Symptomatic; medical inteN/A
Large intestinal anastomot3 Severe symptoms; invasiveN/A
Large intestinal anastomot4 Life-threatening consequen N/A
Large intestinal anastomot5 Death N/A
Large intestinal anastomotDefinition A finding of leakage due t N/A
Pancreatic anastomotic le 1 Asymptomatic diagnostic fiN/A
Pancreatic anastomotic le 2 Symptomatic; medical inteN/A
Pancreatic anastomotic le 3 Severe symptoms; invasiveN/A
Pancreatic anastomotic le 4 Life-threatening consequen N/A
Pancreatic anastomotic le 5 Death N/A
Pancreatic anastomotic le Definition A finding of leakage due t N/A
Pharyngeal anastomotic le1 Asymptomatic diagnostic fiN/A
Pharyngeal anastomotic le2 Symptomatic; medical inteN/A
Pharyngeal anastomotic le3 Severe symptoms; invasiveN/A
Pharyngeal anastomotic le4 Life-threatening consequen N/A
Pharyngeal anastomotic le5 Death N/A
Pharyngeal anastomotic leDefinition A finding of leakage due t N/A
Postoperative hemorrhag 1 Mild symptoms; interventiN/A
Postoperative hemorrhag 2 Moderate bleeding requirin N/A
Postoperative hemorrhag 3 Transfusion indicated of >=N/A
Postoperative hemorrhag 4 Life-threatening consequen N/A
Postoperative hemorrhag 5 Death N/A
Postoperative hemorrhag Definition A disorder characterized bN/A
Postoperative thoracic pr 2 Extubated within 24 - 72 hN/A
Postoperative thoracic pr 3 Extubated >72 hrs postopeN/A
Postoperative thoracic pr 4 Life-threatening airway coN/A
Postoperative thoracic pr 5 Death N/A
Postoperative thoracic pr Definition A finding of a previously N/A
Prolapse of intestinal sto 1 Asymptomatic; reducible N/A
Prolapse of intestinal sto 2 Recurrent after manual reduN/A
Prolapse of intestinal sto 3 Severe symptoms; electiveN/A
Prolapse of intestinal sto 4 Life-threatening consequen N/A
Prolapse of intestinal sto 5 Death N/A
Prolapse of intestinal sto Definition A finding of protrusion of N/A
Prolapse of urostomy 1 Asymptomatic; clinical or N/A
Prolapse of urostomy 2 Local care or maintenance;N/A
Prolapse of urostomy 3 Dysfunctional stoma; electN/A
Prolapse of urostomy 4 Life-threatening consequen N/A
Prolapse of urostomy 5 Death N/A
Prolapse of urostomy Definition A finding of displacement N/A
Radiation recall reaction 1 Faint erythema or dry de N/A
Radiation recall reaction 2 Moderate to brisk erythemN/A
Radiation recall reaction 3 Moist desquamation in areN/A
Radiation recall reaction 4 Life-threatening consequen N/A
Radiation recall reaction 5 Death N/A
Radiation recall reaction Definition A finding of acute skin in N/A
Rectal anastomotic leak 1 Asymptomatic diagnostic fiN/A
Rectal anastomotic leak 2 Symptomatic; medical inteN/A
Rectal anastomotic leak 3 Severe symptoms; invasiveN/A
Rectal anastomotic leak 4 Life-threatening consequen N/A
Rectal anastomotic leak 5 Death N/A
Rectal anastomotic leak Definition A finding of leakage due t N/A
Seroma 1 Asymptomatic; clinical or N/A
Seroma 2 Symptomatic; simple aspirN/A
Seroma 3 Symptomatic, elective invaN/A
Seroma Definition A finding of tumor-like colN/A
Small intestinal anastomot1 Asymptomatic diagnostic fiN/A
Small intestinal anastomot2 Symptomatic; medical inteN/A
Small intestinal anastomot3 Severe symptoms; invasiveN/A
Small intestinal anastomot4 Life-threatening consequen N/A
Small intestinal anastomot5 Death N/A
Small intestinal anastomotDefinition A finding of leakage due t N/A
Spermatic cord anastomoti1 Asymptomatic diagnostic fiN/A
Spermatic cord anastomoti2 Symptomatic; medical inteN/A
Spermatic cord anastomoti3 Severe symptoms; invasiveN/A
Spermatic cord anastomoti4 Life-threatening consequen N/A
Spermatic cord anastomoti5 Death N/A
Spermatic cord anastomotiDefinition A finding of leakage due t N/A
Spinal fracture 1 Mild back pain; nonprescriN/A
Spinal fracture 2 Moderate back pain; prescr N/A
Spinal fracture 3 Severe back pain; hospitalizN/A
Spinal fracture 4 Life-threatening consequ N/A
Spinal fracture 5 Death N/A
Spinal fracture Definition A finding of traumatic injuN/A
Stenosis of gastrointestin 2 Symptomatic; IV fluids indN/A
Stenosis of gastrointestin 3 Severely altered GI functioN/A
Stenosis of gastrointestin 4 Life-threatening consequen N/A
Stenosis of gastrointestin 5 Death N/A
Stenosis of gastrointestin Definition A finding of narrowing of N/A
Stomal ulcer 1 Asymptomatic; clinical or N/A
Stomal ulcer 2 Symptomatic; medical inteN/A
Stomal ulcer 3 Severe symptoms; electiveN/A
Stomal ulcer Definition A disorder characterized bN/A
Tracheal hemorrhage 1 Mild symptoms; interventiN/A
Tracheal hemorrhage 2 Moderate symptoms; interN/A
Tracheal hemorrhage 3 Transfusion indicated; invaN/A
Tracheal hemorrhage 4 Life-threatening consequen N/A
Tracheal hemorrhage 5 Death N/A
Tracheal hemorrhage Definition A disorder characterized bN/A
Tracheal obstruction 1 Partial asymptomatic obstrN/A
Tracheal obstruction 2 Symptomatic (e.g., noisy aiN/A
Tracheal obstruction 3 Stridor or respiratory distrN/A
Tracheal obstruction 4 Life-threatening airway coN/A
Tracheal obstruction 5 Death N/A
Tracheal obstruction Definition A disorder characterized bN/A
Tracheostomy site bleedin1 Minimal bleeding identifieN/A
Tracheostomy site bleedin2 Moderate bleeding; medica N/A
Tracheostomy site bleedin3 Transfusion indicated; inv N/A
Tracheostomy site bleedin4 Life-threatening consequen N/A
Tracheostomy site bleedin5 Death N/A
Tracheostomy site bleedinDefinition A disorder characterized bN/A
Ureteric anastomotic leak 1 Asymptomatic diagnostic fiN/A
Ureteric anastomotic leak 2 Symptomatic; medical inteN/A
Ureteric anastomotic leak 3 Severe symptoms; invasiveN/A
Ureteric anastomotic leak 4 Life-threatening consequen N/A
Ureteric anastomotic leak 5 Death N/A
Ureteric anastomotic leak Definition A finding of leakage due t N/A
Urethral anastomotic leak1 Asymptomatic diagnostic fiN/A
Urethral anastomotic leak2 Symptomatic; medical inteN/A
Urethral anastomotic leak3 Severe symptoms; invasiveN/A
Urethral anastomotic leak4 Life-threatening consequen N/A
Urethral anastomotic leak5 Death N/A
Urethral anastomotic leakDefinition A finding of leakage due t N/A
Urostomy leak 1 Asymptomatic diagnostic fiN/A
Urostomy leak 2 Symptomatic; medical inteN/A
Urostomy leak 3 Severe symptoms; invasiveN/A
Urostomy leak 4 Life-threatening consequen N/A
Urostomy leak 5 Death N/A
Urostomy leak Definition A finding of leakage of co N/A
Urostomy obstruction 1 Asymptomatic; clinical or N/A
Urostomy obstruction 2 Symptomatic; dilation or eN/A
Urostomy obstruction 3 Altered organ function (e.gN/A
Urostomy obstruction 4 Life-threatening consequen N/A
Urostomy obstruction 5 Death N/A
Urostomy obstruction Definition A disorder characterized bN/A
Urostomy site bleeding 1 Minimal bleeding identifieN/A
Urostomy site bleeding 2 Moderate bleeding; medica N/A
Urostomy site bleeding 3 Transfusion indicated; inv N/A
Urostomy site bleeding 4 Life-threatening consequen N/A
Urostomy site bleeding 5 Death N/A
Urostomy site bleeding Definition A disorder characterized bN/A
Urostomy stenosis 2 Symptomatic but no hydrone N/A
Urostomy stenosis 3 Symptomatic (e.g., hydrone N/A
Urostomy stenosis 4 Life-threatening consequen N/A
Urostomy stenosis 5 Death N/A
Urostomy stenosis Definition A finding of narrowing of N/A
Uterine anastomotic leak 1 Asymptomatic diagnostic fiN/A
Uterine anastomotic leak 2 Symptomatic; medical inteN/A
Uterine anastomotic leak 3 Severe symptoms; invasiveN/A
Uterine anastomotic leak 4 Life-threatening consequen N/A
Uterine anastomotic leak 5 Death N/A
Uterine anastomotic leak Definition A finding of leakage due t N/A
Injury, poisoning and proc1 Asymptomatic or mild sympt Uterine perforation
Uterine perforation 2 Invasive intervention not N/A
Uterine perforation 3 Invasive intervention indi N/A
Uterine perforation 4 Life-threatening consequen N/A
Uterine perforation 5 Death N/A
Uterine perforation Definition A disorder characterized byN/A
Vaginal anastomotic leak 1 Asymptomatic diagnostic fiN/A
Vaginal anastomotic leak 2 Symptomatic; medical inteN/A
Vaginal anastomotic leak 3 Severe symptoms; invasiveN/A
Vaginal anastomotic leak 4 Life-threatening consequen N/A
Vaginal anastomotic leak 5 Death N/A
Vaginal anastomotic leak Definition A finding of leakage due t N/A
Vas deferens anastomotic 1 Asymptomatic diagnostic fiN/A
Vas deferens anastomotic 2 Symptomatic; medical inteN/A
Vas deferens anastomotic 3 Severe symptoms; invasiveN/A
Vas deferens anastomotic 4 Life-threatening consequen N/A
Vas deferens anastomotic 5 Death N/A
Vas deferens anastomotic Definition A finding of leakage due t N/A
Vascular access complicat 2 Device dislodgement, block N/A
Vascular access complicat 3 Pulmonary embolism, deep N/A
ve
Vascular access complicat 4 Life-threatening consequeN/A
Vascular access complicat 5 Death N/A
Vascular access complicat Definition A finding of a previously N/A
Venous injury 1 Asymptomatic diagnostic fiN/A
Venous injury 2 Symptomatic (e.g., claudica N/A
Venous injury 3 Severe symptoms; limitingN/A
Venous injury 4 Life-threatening consequeN/A
Venous injury 5 Death N/A
Venous injury Definition A finding of damage to a vN/A
Wound complication 1 Observation only; topical N/A
Wound complication 2 Bedside local care indicat N/A
Wound complication 3 Operative intervention indN/A
Wound complication 4 Life-threatening consequeN/A
Wound complication 5 Death N/A
Wound complication Definition A finding of development oN/A
Wound dehiscence 1 Incisional separation, inte N/A
Wound dehiscence 2 Incisional separation, localN/A
Wound dehiscence 3 Fascial disruption or dehi N/A
Wound dehiscence 4 Life-threatening consequen N/A
Wound dehiscence 5 Death N/A
Wound dehiscence Definition A finding of separation of N/A
Wrist fracture 1 Mild; non-operative intervN/A
Wrist fracture 2 Limiting instrumental ADL;N/A
Wrist fracture 3 Limiting self care ADL; ele N/A
Wrist fracture Definition A finding of traumatic injuN/A
Activated partial thrombo1 >ULN - 1.5 x ULN N/A
Activated partial thrombo2 >1.5 - 2.5 x ULN N/A
Activated partial thrombo3 >2.5 x ULN; bleeding N/A
Activated partial thromboDefinition A finding based on laboratN/A
Alanine aminotransferase 1 >ULN - 3.0 x ULN if baseli N/A
Alanine aminotransferase 2 >3.0 - 5.0 x ULN if baselin N/A
Alanine aminotransferase 3 >5.0 - 20.0 x ULN if baseli N/A
Alanine aminotransferase 4 >20.0 x ULN if baseline waN/A
Alanine aminotransferase Definition A finding based on laboratN/A
Alkaline phosphatase incr 1 >ULN - 2.5 x ULN if baseli N/A
Alkaline phosphatase incr 2 >2.5 - 5.0 x ULN if baselin N/A
Alkaline phosphatase incr 3 >5.0 - 20.0 x ULN if baseli N/A
Alkaline phosphatase incr 4 >20.0 x ULN if baseline waN/A
Alkaline phosphatase incr Definition A finding based on laborato N/A
Aspartate aminotransferas1 >ULN - 3.0 x ULN if baseli N/A
Aspartate aminotransferas2 >3.0 - 5.0 x ULN if baselin N/A
Aspartate aminotransferas3 >5.0 - 20.0 x ULN if baseli N/A
Aspartate aminotransferas4 >20.0 x ULN if baseline waN/A
Aspartate aminotransferasDefinition A finding based on laboratN/A
Blood antidiuretic hormo 1 Asymptomatic; clinical or N/A
Blood antidiuretic hormo 2 Symptomatic; medical inteN/A
Blood antidiuretic hormo 3 Hospitalization indicated N/A
Blood antidiuretic hormo Definition A finding based on laboratN/A
Blood bilirubin increased 1 >ULN - 1.5 x ULN if baseli N/A
Blood bilirubin increased 2 >1.5 - 3.0 x ULN if baselin N/A
Blood bilirubin increased 3 >3.0 - 10.0 x ULN if baseli N/A
Blood bilirubin increased 4 >10.0 x ULN if baseline waN/A
Blood bilirubin increased Definition A finding based on laborato N/A
Blood corticotrophin decr 1 Asymptomatic; clinical or N/A
Blood corticotrophin decr 2 Symptomatic; medical inteN/A
Blood corticotrophin decr 3 Hospitalization indicated N/A
Blood corticotrophin decr Definition A finding based on laborato N/A
Blood gonadotrophin abn 1 Asymptomatic; clinical or N/A
Blood gonadotrophin abn 2 Symptomatic; medical inter N/A
Blood gonadotrophin abn 3 Severe symptoms; limitingN/A
Blood gonadotrophin abn Definition A finding based on laboratN/A
Blood prolactin abnormal 1 Asymptomatic; clinical or N/A
Blood prolactin abnormal 2 Moderate symptoms; limitN/A
Blood prolactin abnormal Definition A finding based on laboratN/A
Carbon monoxide diffusing1 3 - 5 units below LLN; for N/A
Carbon monoxide diffusing2 6 - 8 units below LLN; for N/A
Carbon monoxide diffusing3 Asymptomatic decrease ofN/A
Carbon monoxide diffusingDefinition A finding based on lung fuN/A
Cardiac troponin I increas 1 Levels above the upper limN/A
Cardiac troponin I increas 3 Levels consistent with myoN/A
Cardiac troponin I increas Definition A finding based on laborato N/A
Cardiac troponin T increa 1 Levels above the upper limN/A
Cardiac troponin T increa 3 Levels consistent with myoN/A
Cardiac troponin T increa Definition A finding based on laborato N/A
CD4 lymphocytes decreas 1 <LLN - 500/mm3; <LLN - 0.N/A
CD4 lymphocytes decreas 2 <500 - 200/mm3; <0.5 - 0.N/A
CD4 lymphocytes decreas 3 <200 - 50/mm3; <0.2 x 0.0N/A
CD4 lymphocytes decreas 4 <50/mm3; <0.05 x 10e9 /LN/A
CD4 lymphocytes decreas Definition A finding based on laboratN/A
Cholesterol high 1 >ULN - 300 mg/dL; >ULN -N/A
Cholesterol high 2 >300 - 400 mg/dL; >7.75 - N/A
Cholesterol high 3 >400 - 500 mg/dL; >10.34 N/A
Cholesterol high 4 >500 mg/dL; >12.92 mmolN/A
Cholesterol high Definition A finding based on laborato N/A
CPK increased 1 >ULN - 2.5 x ULN N/A
CPK increased 2 >2.5 x ULN - 5 x ULN N/A
CPK increased 3 >5 x ULN - 10 x ULN N/A
CPK increased 4 >10 x ULN N/A
CPK increased Definition A finding based on laboratN/A
Creatinine increased 1 >ULN - 1.5 x ULN N/A
Creatinine increased 2 >1.5 - 3.0 x baseline; >1.5 N/A
Creatinine increased 3 >3.0 x baseline; >3.0 - 6.0 N/A
Creatinine increased 4 >6.0 x ULN N/A
Creatinine increased Definition A finding based on laborato N/A
Ejection fraction decrease2 Resting ejection fraction N/A
Ejection fraction decreaseDefinition The percentage computedN/A w
Electrocardiogram QT corr1 Average QTc 450 - 480 msN/A
Electrocardiogram QT corr2 Average QTc 481 - 500 msN/A
Electrocardiogram QT corr3 Average QTc >= 501 ms; >N/A
Electrocardiogram QT corr4 Torsade de pointes; polymN/A
Electrocardiogram QT corrDefinition A finding of a cardiac dys N/A
Fibrinogen decreased 1 <1.0 - 0.75 x LLN; if abno N/A
Fibrinogen decreased 4 <0.25 x LLN; if abnormal, N/A
Fibrinogen decreased Definition A finding based on laborato N/A
Forced expiratory volume 1 FEV1% (percentages of obsN/A
Forced expiratory volume 2 FEV1 60 - 69% N/A
Forced expiratory volume 3 50 - 59% N/A
Forced expiratory volume 4 <= 49% N/A
Forced expiratory volume Definition A finding based on test resN/A
GGT increased 1 >ULN - 2.5 x ULN if baseli N/A
GGT increased 2 >2.5 - 5.0 x ULN if baselin N/A
GGT increased 3 >5.0 - 20.0 x ULN if baseli N/A
GGT increased 4 >20.0 x ULN if baseline waN/A
GGT increased Definition A finding based on labora N/A
Growth hormone abnorma1 Asymptomatic; clinical or N/A
Growth hormone abnorma2 Symptomatic; medical inter N/A
Growth hormone abnormaDefinition A finding based on laboratN/A
Haptoglobin decreased 1 <LLN N/A
Haptoglobin decreased Definition A finding based on laborato N/A
Hemoglobin increased 1 Increase in >0 - 2 g/dL N/A
Hemoglobin increased 2 Increase in >2 - 4 g/dL N/A
Hemoglobin increased 3 Increase in >4 g/dL N/A
Hemoglobin increased Definition A finding based on laboratN/A
INR increased 1 >1.2 - 1.5; >1 - 1.5 x base N/A
INR increased 2 >1.5 - 2.5; >1.5 - 2.5 x ba N/A
INR increased 3 >2.5; >2.5 x baseline if on N/A
INR increased Definition A finding based on laborato N/A
Investigations - Other, spe1 Asymptomatic or mild sympt N/A
Investigations - Other, spe2 Moderate; minimal, local oN/A
Investigations - Other, spe3 Severe or medically signifiN/A
Investigations - Other, spe4 Life-threatening consequen N/A
Investigations - Other, spe5 Death N/A
Lipase increased 1 >ULN - 1.5 x ULN N/A
Lipase increased 2 >1.5 - 2.0 x ULN; >2.0 - 5 N/A
Lipase increased 3 >2.0 - 5.0 x ULN with sig N/A
Lipase increased 4 >5.0 x ULN and with signs N/A
Lipase increased Definition A finding based on laboratoN/A
Lymphocyte count decrea1 <LLN - 800/mm3; <LLN - 0.N/A
Lymphocyte count decrea2 <800 - 500/mm3; <0.8 - 0.N/A
Lymphocyte count decrea3 <500 - 200/mm3; <0.5 - 0.N/A
Lymphocyte count decrea4 <200/mm3; <0.2 x 10e9 /LN/A
Lymphocyte count decreaDefinition A finding based on laboratN/A
Lymphocyte count increas2 >4000/mm3 - 20,000/mmN/A
Lymphocyte count increas3 >20,000/mm3 N/A
Lymphocyte count increasDefinition A finding based on laboratN/A
Neutrophil count decreas 1 <LLN - 1500/mm3; <LLN - 1N/A
Neutrophil count decreas 2 <1500 - 1000/mm3; <1.5 -N/A
Neutrophil count decreas 3 <1000 - 500/mm3; <1.0 - 0N/A
Neutrophil count decreas 4 <500/mm3; <0.5 x 10e9 /LN/A
Neutrophil count decreas Definition A finding based on laboratN/A
Pancreatic enzymes decre1 <LLN and asymptomatic N/A
Pancreatic enzymes decre2 Increase in stool frequencyN/A
Pancreatic enzymes decre3 Sequelae of absorption deN/A
Pancreatic enzymes decreDefinition A finding based on laboratoN/A
Platelet count decreased 1 <LLN - 75,000/mm3; <LLN N/A-
Platelet count decreased 2 <75,000 - 50,000/mm3; <75 N/A
Platelet count decreased 3 <50,000 - 25,000/mm3; <50 N/A
Platelet count decreased 4 <25,000/mm3; <25.0 x 10eN/A
Platelet count decreased Definition A finding based on laboratN/A
Serum amylase increased 1 >ULN - 1.5 x ULN N/A
Serum amylase increased 2 >1.5 - 2.0 x ULN; >2.0 - 5 N/A
Serum amylase increased 3 >2.0 - 5.0 x ULN with sig N/A
Serum amylase increased 4 >5.0 x ULN and with signs N/A
Serum amylase increased Definition A finding based on laboratoN/A
Urine output decreased 3 Children: < 500 mL/1.73 m2 N/A
body surface area per day
Urine output decreased 4 Pediatric: No urine outputN/A
over 12 hours
Urine output decreased Definition A finding based on test resN/A
Vital capacity abnormal 1 90 - 75% of predicted valuN/A
Vital capacity abnormal 2 <75 - 50% of predicted valN/A
Vital capacity abnormal 3 <50% of predicted value; lN/A
Vital capacity abnormal Definition A finding based on pulmona N/A
Weight gain 1 5 - <10% from baseline N/A
Weight gain 2 10 - <20% from baseline N/A
Weight gain 3 >=20% from baseline N/A
Weight gain Definition A finding characterized byN/A
Weight loss 1 5 to <10% from baseline; iN/A
Weight loss 2 10 - <20% from baseline; nN/A
Weight loss 3 >=20% from baseline; tubeN/A
Weight loss Definition A finding characterized by N/A
White blood cell decrease1 <LLN - 3000/mm3; <LLN - 3N/A
White blood cell decrease2 <3000 - 2000/mm3; <3.0 -N/A
White blood cell decrease3 <2000 - 1000/mm3; <2.0 -N/A
White blood cell decrease4 <1000/mm3; <1.0 x 10e9 /N/A
White blood cell decreaseDefinition A finding based on laboratN/A
Acidosis 1 pH <normal, but >=7.3 N/A
Acidosis 3 pH <7.3 N/A
Acidosis 4 Life-threatening consequeN/A
Acidosis 5 Death N/A
Acidosis Definition A disorder characterized bN/A
Alcohol intolerance 2 Present N/A
Alcohol intolerance 3 Severe symptoms; limitingN/A
Alcohol intolerance 4 Life-threatening consequen N/A
Alcohol intolerance 5 Death N/A
Alcohol intolerance Definition A disorder characterized bN/A
Alkalosis 1 pH >normal, but <=7.5 N/A
Alkalosis 3 pH >7.5 N/A
Alkalosis 4 Life-threatening consequeN/A
Alkalosis 5 Death N/A
Alkalosis Definition A disorder characterized bN/A
Anorexia 1 Loss of appetite without alN/A
Anorexia 2 Oral intake altered withoutN/A
Anorexia 3 Associated with significantN/A
Anorexia 4 Life-threatening consequen N/A
Anorexia 5 Death N/A
Anorexia Definition A disorder characterized byN/A
Dehydration 1 Increased oral fluids ind N/A
Dehydration 2 IV fluids indicated N/A
Dehydration 3 Hospitalization indicated N/A
Dehydration 4 Life-threatening consequen N/A
Dehydration 5 Death N/A
Dehydration Definition A disorder characterized byN/A
Glucose intolerance 1 Asymptomatic; clinical or N/A
Glucose intolerance 2 Symptomatic; dietary modif N/A
Glucose intolerance 3 Severe symptoms; insulin N/A
Glucose intolerance 4 Life-threatening consequen N/A
Glucose intolerance 5 Death N/A
Glucose intolerance Definition A disorder characterized bN/A
Hypercalcemia 1 Corrected serum calcium oN/A
Hypercalcemia 3 Corrected serum calcium of N/A
Hypercalcemia 5 Death N/A
Hypercalcemia Definition A disorder characterized byN/A
Hyperglycemia 1 Abnormal glucose above ba N/A
Hyperglycemia 2 Change in daily management N/Afrom baseline for a diabetic; oral antiglycemic a
Hyperglycemia 3 Insulin therapy initiated; N/A
Hyperglycemia 4 Life-threatening consequen N/A
Hyperglycemia 5 Death N/A
Hyperglycemia Definition A disorder characterized byN/A
Hyperkalemia 1 >ULN - 5.5 mmol/L N/A
Hyperkalemia 2 >5.5 - 6.0 mmol/L; intervenN/A
Hyperkalemia 3 >6.0 - 7.0 mmol/L; hospitaN/A
Hyperkalemia 4 >7.0 mmol/L; life-threate N/A
Hyperkalemia 5 Death N/A
Hyperkalemia Definition A disorder characterized byN/A
Hypermagnesemia 1 >ULN - 3.0 mg/dL; >ULN - N/A
Hypermagnesemia 3 >3.0 - 8.0 mg/dL; >1.23 - N/A
Hypermagnesemia 4 >8.0 mg/dL; >3.30 mmol/L;N/A
Hypermagnesemia 5 Death N/A
Hypermagnesemia Definition A disorder characterized bN/A
Hypernatremia 1 >ULN - 150 mmol/L N/A
Hypernatremia 2 >150 - 155 mmol/L; interveN/A
Hypernatremia 3 >155 - 160 mmol/L; hospita N/A
Hypernatremia 4 >160 mmol/L; life-threat N/A
Hypernatremia 5 Death N/A
Hypernatremia Definition A disorder characterized byN/A
Hypertriglyceridemia 1 150 mg/dL - 300 mg/dL; 1 N/A
Hypertriglyceridemia 2 >300 mg/dL - 500 mg/dL; N/A
Hypertriglyceridemia 3 >500 mg/dL - 1000 mg/dL;N/A
Hypertriglyceridemia 4 >1000 mg/dL; >11.4 mmol/N/A
Hypertriglyceridemia 5 Death N/A
Hypertriglyceridemia Definition A disorder characterized byN/A
Hyperuricemia 1 >ULN without physiologic N/A
Hyperuricemia 3 >ULN with physiologic co N/A
Hyperuricemia 4 Life-threatening consequeN/A
Hyperuricemia 5 Death N/A
Hyperuricemia Definition A disorder characterized byN/A
Hypoalbuminemia 1 <LLN - 3 g/dL; <LLN - 30 g/N/A
Hypoalbuminemia 2 <3 - 2 g/dL; <30 - 20 g/L N/A
Hypoalbuminemia 3 <2 g/dL; <20 g/L N/A
Hypoalbuminemia 4 Life-threatening consequen N/A
Hypoalbuminemia 5 Death N/A
Hypoalbuminemia Definition A disorder characterized bN/A
Hypocalcemia 1 Corrected serum calcium oN/A
Hypocalcemia 3 Corrected serum calcium of N/A
Hypocalcemia 5 Death N/A
Hypocalcemia Definition A disorder characterized byN/A
Hypoglycemia 1 <LLN - 55 mg/dL; <LLN - 3 N/A
Hypoglycemia 2 <55 - 40 mg/dL; <3.0 - 2. N/A
Hypoglycemia 3 <40 - 30 mg/dL; <2.2 - 1. N/A
Hypoglycemia 4 <30 mg/dL; <1.7 mmol/L; lN/A
Hypoglycemia 5 Death N/A
Hypoglycemia Definition A disorder characterized byN/A
Hypokalemia 1 <LLN - 3.0 mmol/L N/A
Hypokalemia 2 Symptomatic with <LLN - 3N/A
Hypokalemia 3 <3.0 - 2.5 mmol/L; hospitaN/A
Hypokalemia 4 <2.5 mmol/L; life-threate N/A
Hypokalemia 5 Death N/A
Hypokalemia Definition A disorder characterized bN/A
Hypomagnesemia 1 <LLN - 1.2 mg/dL; <LLN - N/A
Hypomagnesemia 2 <1.2 - 0.9 mg/dL; <0.5 - 0 N/A
Hypomagnesemia 3 <0.9 - 0.7 mg/dL; <0.4 - 0 N/A
Hypomagnesemia 4 <0.7 mg/dL; <0.3 mmol/L; N/A
Hypomagnesemia 5 Death N/A
Hypomagnesemia Definition A disorder characterized bN/A
Hyponatremia 1 <LLN - 130 mmol/L N/A
Hyponatremia 3 125-129 mmol/L symptomat N/A
Hyponatremia 4 <120 mmol/L; life-threat N/A
Hyponatremia 5 Death N/A
Hyponatremia Definition A disorder characterized bN/A
Hypophosphatemia 1 Laboratory finding only anN/A
Hypophosphatemia 2 Oral replacement therapy N/A
Hypophosphatemia 3 Severe or medically signifiN/A
Hypophosphatemia 4 Life-threatening consequeN/A
Hypophosphatemia 5 Death N/A
Hypophosphatemia Definition A disorder characterized bN/A
Iron overload 2 Moderate symptoms; interN/A
Iron overload 3 Severe symptoms; interven N/A
Iron overload 4 Life-threatening consequen N/A
Iron overload 5 Death N/A
Iron overload Definition A disorder characterized byN/A
Metabolism and nutrition 1d Asymptomatic or mild sympt N/A
Metabolism and nutrition 2d Moderate; minimal, local oN/A
Metabolism and nutrition 3d Severe or medically signifiN/A
Metabolism and nutrition 4d Life-threatening consequen N/A
Metabolism and nutrition 5d Death N/A
Obesity 2 BMI 25 - 29.9 kg/m2 N/A
Obesity 3 BMI 30 - 39.9 kg/m2 N/A
Obesity 4 BMI >=40 kg/m2 N/A
Obesity Definition A disorder characterized bN/A
Tumor lysis syndrome 3 Present N/A
Tumor lysis syndrome 4 Life-threatening consequen N/A
Tumor lysis syndrome 5 Death N/A
Tumor lysis syndrome Definition A disorder characterized bN/A
Abdominal soft tissue necr2 Local wound care; medicalN/A
Abdominal soft tissue necr3 Operative debridement orN/Aot
Abdominal soft tissue necr4 Life-threatening consequen N/A
Abdominal soft tissue necr5 Death N/A
Abdominal soft tissue necrDefinition A disorder characterized byN/A
Arthralgia 1 Mild pain N/A
Arthralgia 2 Moderate pain; limiting i N/A
Arthralgia 3 Severe pain; limiting self N/A
Arthralgia Definition A disorder characterized bN/A
Arthritis 1 Mild pain with inflammatioN/A
Arthritis 2 Moderate pain associated N/A
w
Arthritis 3 Severe pain associated withN/A
Arthritis Definition A disorder characterized bN/A
Avascular necrosis 1 Asymptomatic; clinical or N/A
Avascular necrosis 2 Symptomatic; limiting ins N/A
Avascular necrosis 3 Severe symptoms; limitingN/A
Avascular necrosis 4 Life-threatening consequen N/A
Avascular necrosis 5 Death N/A
Avascular necrosis Definition A disorder characterized bN/A
Back pain 1 Mild pain N/A
Back pain 2 Moderate pain; limiting i N/A
Back pain 3 Severe pain; limiting self N/A
Back pain Definition A disorder characterized bN/A
Bone pain 1 Mild pain N/A
Bone pain 2 Moderate pain; limiting i N/A
Bone pain 3 Severe pain; limiting self N/A
Bone pain Definition A disorder characterized bN/A
Buttock pain 1 Mild pain N/A
Buttock pain 2 Moderate pain; limiting i N/A
Buttock pain 3 Severe pain; limiting self N/A
Buttock pain Definition A disorder characterized bN/A
Chest wall pain 1 Mild pain N/A
Chest wall pain 2 Moderate pain; limiting i N/A
Chest wall pain 3 Severe pain; limiting self N/A
Chest wall pain Definition A disorder characterized bN/A
Exostosis 1 Asymptomatic; clinical or N/A
Exostosis 2 Symptomatic; limiting ins N/A
Exostosis 3 Severe symptoms; limitingN/A
Exostosis Definition A disorder characterized N/A
Fibrosis deep connective t1 Mild induration, able to mo N/A
Fibrosis deep connective t2 Moderate induration, ableN/A t
Fibrosis deep connective t3 Severe induration; unable N/At
Fibrosis deep connective t4 Generalized; associated wN/A
Fibrosis deep connective t5 Death N/A
Fibrosis deep connective tDefinition A disorder characterized bN/A
Flank pain 1 Mild pain N/A
Flank pain 2 Moderate pain; limiting i N/A
Flank pain 3 Severe pain; limiting self N/A
Flank pain Definition A disorder characterized bN/A
Generalized muscle weakn1 Symptomatic; perceived byN/A
Generalized muscle weakn2 Symptomatic; evident on pN/A
Generalized muscle weakn3 Limiting self care ADL N/A
Generalized muscle weaknDefinition A disorder characterized bN/A
Growth suppression 1 Reduction in growth velociN/A
Growth suppression Definition A disorder characterized bN/A
Head soft tissue necrosis 2 Local wound care; medicalN/A
Head soft tissue necrosis 3 Operative debridement orN/A ot
Head soft tissue necrosis 4 Life-threatening consequen N/A
Head soft tissue necrosis 5 Death N/A
Head soft tissue necrosis Definition A disorder characterized by N/A
Joint effusion 1 Asymptomatic; clinical or N/A
Joint effusion 2 Symptomatic; limiting ins N/A
Joint effusion 3 Severe symptoms; limitingN/A
Joint effusion Definition A disorder characterized by N/A
Joint range of motion dec 1 <=25% loss of ROM (rangeN/A o
Joint range of motion dec 2 >25 - 50% decrease in ROM N/A
Joint range of motion dec 3 >50% decrease in ROM; lim N/A
Joint range of motion dec Definition A disorder characterized by N/A
Joint range of motion decr1 Mild restriction of rotatio N/A
Joint range of motion decr2 Rotation <60 degrees to rigN/A
Joint range of motion decr3 Ankylosed/fused over multN/A
Joint range of motion decrDefinition A disorder characterized by N/A
Joint range of motion dec 1 Stiffness; difficulty bendin N/A
Joint range of motion dec 2 Pain with range of motion N/A
Joint range of motion dec 3 <50% lumbar spine flexion;N/A
Joint range of motion dec Definition A disorder characterized by N/A
Kyphosis 1 Asymptomatic; clinical or N/A
Kyphosis 2 Moderate accentuation; liN/A
Kyphosis 3 Severe accentuation; opera N/A
Kyphosis Definition A disorder characterized bN/A
Lordosis 1 Asymptomatic; clinical or N/A
Lordosis 2 Moderate accentuation; liN/A
Lordosis 3 Severe accentuation; opera N/A
Lordosis Definition A disorder characterized bN/A
Muscle weakness left-side1 Symptomatic; perceived byN/A
Muscle weakness left-side2 Symptomatic; evident on pN/A
Muscle weakness left-side3 Limiting self care ADL N/A
Muscle weakness left-sideDefinition A disorder characterized byN/A
Muscle weakness lower li 1 Symptomatic; perceived byN/A
Muscle weakness lower li 2 Symptomatic; evident on pN/A
Muscle weakness lower li 3 Limiting self care ADL N/A
Muscle weakness lower li Definition A disorder characterized bN/A
Muscle weakness right-si 1 Symptomatic; perceived byN/A
Muscle weakness right-si 2 Symptomatic; evident on pN/A
Muscle weakness right-si 3 Limiting self care ADL N/A
Muscle weakness right-si Definition A disorder characterized byN/A
Muscle weakness trunk 1 Symptomatic; perceived byN/A
Muscle weakness trunk 2 Symptomatic; evident on pN/A
Muscle weakness trunk 3 Limiting self care ADL N/A
Muscle weakness trunk Definition A disorder characterized bN/A
Muscle weakness upper l 1 Symptomatic; perceived byN/A
Muscle weakness upper l 2 Symptomatic; evident on pN/A
Muscle weakness upper l 3 Limiting self care ADL N/A
Muscle weakness upper l Definition A disorder characterized bN/A
Musculoskeletal and connec1 Asymptomatic or mild sympt N/A
Musculoskeletal and connec2 Moderate; minimal, local oN/A
Musculoskeletal and connec3 Severe or medically signifiN/A
Musculoskeletal and connec4 Life-threatening consequen N/A
Musculoskeletal and connec5 Death N/A
Musculoskeletal deformity1 Cosmetically and functionalN/A
Musculoskeletal deformity2 Deformity, hypoplasia, or N/A
Musculoskeletal deformity3 Significant deformity, hyp N/A
Musculoskeletal deformityDefinition A disorder characterized N/A
Myalgia 1 Mild pain N/A
Myalgia 2 Moderate pain; limiting i N/A
Myalgia 3 Severe pain; limiting self N/A
Myalgia Definition A disorder characterized bN/A
Myositis 1 Mild pain N/A
Myositis 2 Moderate pain associated N/A
Myositis 3 Pain associated with severN/A
Myositis Definition A disorder characterized bN/A
Neck pain 1 Mild pain N/A
Neck pain 2 Moderate pain; limiting i N/A
Neck pain 3 Severe pain; limiting self N/A
Neck pain Definition A disorder characterized bN/A
Neck soft tissue necrosis 2 Local wound care; medicalN/A
Neck soft tissue necrosis 3 Operative debridement orN/A ot
Neck soft tissue necrosis 4 Life-threatening consequen N/A
Neck soft tissue necrosis 5 Death N/A
Neck soft tissue necrosis Definition A disorder characterized by N/A
Osteonecrosis of jaw 1 Asymptomatic; clinical or N/A
Osteonecrosis of jaw 2 Symptomatic; medical inter N/A
Osteonecrosis of jaw 3 Severe symptoms; limitingN/A
Osteonecrosis of jaw 4 Life-threatening consequen N/A
Osteonecrosis of jaw 5 Death N/A
Osteonecrosis of jaw Definition A disorder characterized bN/A
Osteoporosis 1 N/A of low BMD with z score of <= -2.0 and no hist
Pediatric: Radiologic evidence
Osteoporosis 2 Pediatric: Low BMD (z-score N/A<= -2.0) and significant fracture history (defined
Osteoporosis 3 Pediatric: Limiting self careN/A
ADL
Osteoporosis Definition A disorder characterized bN/A
Pain in extremity 1 Mild pain N/A
Pain in extremity 2 Moderate pain; limiting i N/A
Pain in extremity 3 Severe pain; limiting self N/A
Pain in extremity Definition A disorder characterized bN/A
Pelvic soft tissue necrosis 2 Local wound care; medicalN/A
Pelvic soft tissue necrosis 3 Operative debridement orN/A ot
Pelvic soft tissue necrosis 4 Life-threatening consequen N/A
Pelvic soft tissue necrosis 5 Death N/A
Pelvic soft tissue necrosis Definition A disorder characterized by N/A
Scoliosis 1 <20 degrees; clinically un N/A
Scoliosis 2 >20 - 45 degrees; visible bN/A
Scoliosis 3 >45 degrees; scapular prom N/A
Scoliosis Definition A disorder characterized bN/A
Soft tissue necrosis lower 2 Local wound care; medicalN/A
Soft tissue necrosis lower 3 Operative debridement orN/A ot
Soft tissue necrosis lower 4 Life-threatening consequen N/A
Soft tissue necrosis lower 5 Death N/A
Soft tissue necrosis lower Definition A disorder characterized by N/A
Soft tissue necrosis upper 2 Local wound care; medicalN/A
Soft tissue necrosis upper 3 Operative debridement orN/A ot
Soft tissue necrosis upper 4 Life-threatening consequen N/A
Soft tissue necrosis upper 5 Death N/A
Soft tissue necrosis upper Definition A disorder characterized by N/A
Superficial soft tissue fibro1 Mild induration, able to mo N/A
Superficial soft tissue fibro2 Moderate induration, ableN/A t
Superficial soft tissue fibro3 Severe induration; unable N/At
Superficial soft tissue fibro4 Generalized; associated wN/A
Superficial soft tissue fibro5 Death N/A
Superficial soft tissue fibroDefinition A disorder characterized by N/A
Trismus 1 Decreased ROM (range of N/A
Trismus 2 Decreased ROM requiring N/A sm
Trismus 3 Decreased ROM with inabili N/A
Trismus Definition A disorder characterized bN/A
Unequal limb length 1 Mild length discrepancy < N/A
Unequal limb length 2 Moderate length discrepanc N/A
Unequal limb length 3 Severe length discrepancyN/A
Unequal limb length Definition A disorder characterized bN/A
Leukemia secondary to o 4 Present N/A
Leukemia secondary to o 5 Death N/A
Leukemia secondary to o Definition A disorder characterized bN/A
Myelodysplastic syndrome4 Life-threatening consequen N/A
Myelodysplastic syndrome5 Death N/A
Myelodysplastic syndromeDefinition A disorder characterized bN/A
Neoplasms benign, malignan1 Asymptomatic or mild sympt N/A
Neoplasms benign, malignan2 Moderate; minimal, local oN/A
Neoplasms benign, malignan3 Severe or medically signifiN/A
Neoplasms benign, malignan4 Life-threatening consequen N/A
Neoplasms benign, malignan5 Death N/A
Treatment related second3 Non life-threatening seco N/A
Treatment related second4 Acute life-threatening sec N/A
Treatment related second5 Death N/A
Treatment related secondDefinition A disorder characterized bN/A
Tumor pain 1 Mild pain N/A
Tumor pain 2 Moderate pain; limiting i N/A
Tumor pain 3 Severe pain; limiting self N/A
Tumor pain Definition A disorder characterized bN/A
Abducens nerve disorder 1 Asymptomatic; clinical or N/A
Abducens nerve disorder 2 Moderate symptoms; limitN/A
Abducens nerve disorder 3 Severe symptoms; limitingN/A
Abducens nerve disorder Definition A disorder characterized bN/A
Accessory nerve disorder 1 Asymptomatic; clinical or N/A
Accessory nerve disorder 2 Moderate symptoms; limitN/A
Accessory nerve disorder 3 Severe symptoms; limitingN/A
Accessory nerve disorder Definition A disorder characterized bN/A
Acoustic nerve disorder N 1 Asymptomatic; clinical or N/A
Acoustic nerve disorder N 2 Moderate symptoms; limitN/A
Acoustic nerve disorder N 3 Severe symptoms; limitingN/A
Acoustic nerve disorder N Definition A disorder characterized bN/A
Akathisia 1 Mild restlessness or incre N/A
Akathisia 2 Moderate restlessness or iN/A
Akathisia 3 Severe restlessness or incrN/A
Akathisia Definition A disorder characterized byN/A
Amnesia 1 Mild; transient memory loN/A
Amnesia 2 Moderate; short term memo N/A
Amnesia 3 Severe; long term memoryN/A l
Amnesia Definition A disorder characterized bN/A
Aphonia 3 Voicelessness; unable to N/A
Aphonia Definition A disorder characterized byN/A
Arachnoiditis 1 Mild symptoms N/A
Arachnoiditis 2 Moderate symptoms; limitN/A
Arachnoiditis 3 Severe symptoms; limitingN/A
Arachnoiditis 4 Life-threatening consequen N/A
Arachnoiditis 5 Death N/A
Arachnoiditis Definition A disorder characterized N/A
Ataxia 1 Asymptomatic; clinical or N/A
Ataxia 2 Moderate symptoms; limitN/A
Ataxia 3 Severe symptoms; limitingN/A
Ataxia Definition A disorder characterized bN/A
Brachial plexopathy 1 Asymptomatic; clinical or N/A
Brachial plexopathy 2 Moderate symptoms; limitN/A
Brachial plexopathy 3 Severe symptoms; limitingN/A
Brachial plexopathy Definition A disorder characterized N/A
Central nervous system ne1 Asymptomatic; clinical or N/A
Central nervous system ne2 Moderate symptoms; cortic N/A
Central nervous system ne3 Severe symptoms; medicalN/A
Central nervous system ne4 Life-threatening consequen N/A
Central nervous system ne5 Death N/A
Central nervous system neDefinition A disorder characterized byN/A
Cerebrospinal fluid leakag1 Post-craniotomy: asymptom N/A
Cerebrospinal fluid leakag2 Post-craniotomy: moderate N/A
Cerebrospinal fluid leakag3 Severe symptoms; medicalN/A
Cerebrospinal fluid leakag4 Life-threatening consequen N/A
Cerebrospinal fluid leakag5 Death N/A
Cerebrospinal fluid leakagDefinition A disorder characterized byN/A
Cognitive disturbance 1 Mild cognitive disability; N/A
Cognitive disturbance 2 Moderate cognitive disabilN/A
Cognitive disturbance 3 Severe cognitive disabilit N/A
Cognitive disturbance Definition A disorder characterized bN/A
Concentration impairment1 Mild inattention or decreaN/A
Concentration impairment2 Moderate impairment in att N/A
Concentration impairment3 Severe impairment in attenN/A
Concentration impairmentDefinition A disorder characterized byN/A
Depressed level of consci 1 Decreased level of alertneN/A
Depressed level of consci 2 Sedation; slow response toN/A
Depressed level of consci 3 Difficult to arouse N/A
Depressed level of consci 4 Life-threatening consequeN/A
Depressed level of consci 5 Death N/A
Depressed level of consci Definition A disorder characterized bN/A
Dizziness 1 Mild unsteadiness or sen N/A
Dizziness 2 Moderate unsteadiness orN/A
Dizziness 3 Severe unsteadiness or senN/A
Dizziness Definition A disorder characterized bN/A
Dysarthria 1 Mild slurred speech N/A
Dysarthria 2 Moderate impairment of ar N/A
Dysarthria 3 Severe impairment of articN/A
Dysarthria Definition A disorder characterized bN/A
Dysesthesia 1 Mild sensory alteration N/A
Dysesthesia 2 Moderate sensory alteratioN/A
Dysesthesia 3 Severe sensory alteration;N/A
Dysesthesia Definition A disorder characterized bN/A
Dysgeusia 1 Altered taste but no changN/A
Dysgeusia 2 Altered taste with change N
i /A
Dysgeusia Definition A disorder characterized bN/A
Dysphasia 1 Awareness of receptive orN/A
Dysphasia 2 Moderate receptive or exprN/A
Dysphasia 3 Severe receptive or express
N/A
Dysphasia Definition A disorder characterized bN/A
Edema cerebral 4 Life-threatening consequenN/A
Edema cerebral Definition A disorder characterized by
N/A
Encephalopathy 1 Mild symptoms N/A
Encephalopathy 2 Moderate symptoms; limitN/A
Encephalopathy 3 Severe symptoms; limitingN/A
Encephalopathy 4 Life-threatening consequenN/A
Encephalopathy 5 Death N/A
Encephalopathy Definition A disorder characterized bN/A
Extrapyramidal disorder 1 Mild involuntary movemenN/A
Extrapyramidal disorder 2 Moderate involuntary movN/A
Extrapyramidal disorder 3 Severe involuntary movement
N/A
Extrapyramidal disorder 4 Life-threatening consequenN/A
Extrapyramidal disorder 5 Death N/A
Extrapyramidal disorder Definition A disorder characterized N/A
Facial muscle weakness 1 Asymptomatic; clinical or N/A
Facial muscle weakness 2 Moderate symptoms; limitN/A
Facial muscle weakness 3 Severe symptoms; limitingN/A
Facial muscle weakness Definition A disorder characterized by
N/A
Facial nerve disorder 1 Asymptomatic; clinical or N/A
Facial nerve disorder 2 Moderate symptoms; limitN/A
Facial nerve disorder 3 Severe symptoms; limitingN/A
Facial nerve disorder Definition A disorder characterized by
N/A
Glossopharyngeal nerve di1 Asymptomatic; clinical or N/A
Glossopharyngeal nerve di2 Moderate symptoms; limitN/A
Glossopharyngeal nerve di3 Severe symptoms; limitingN/A
Glossopharyngeal nerve di4 Life-threatening consequenN/A
Glossopharyngeal nerve di5 Death N/A
Glossopharyngeal nerve diDefinition A disorder characterized bN/A
Headache 1 Mild pain N/A
Headache 2 Moderate pain; limiting i N/A
Headache 3 Severe pain; limiting self N/A
Headache Definition A disorder characterized bN/A
Hydrocephalus 1 Asymptomatic; clinical or N/A
Hydrocephalus 2 Moderate symptoms; interN/A
Hydrocephalus 3 Severe symptoms or neurolo N/A
Hydrocephalus 4 Life-threatening consequen N/A
Hydrocephalus 5 Death N/A
Hydrocephalus Definition A disorder characterized byN/A
Hypersomnia 1 Mild increased need for slN/A
Hypersomnia 2 Moderate increased need N/Af
Hypersomnia 3 Severe increased need forN/A
Hypersomnia Definition A disorder characterized bN/A
Hypoglossal nerve disorde1 Asymptomatic; clinical or N/A
Hypoglossal nerve disorde2 Moderate symptoms; limitN/A
Hypoglossal nerve disorde3 Severe symptoms; limitingN/A
Hypoglossal nerve disordeDefinition A disorder characterized bN/A
Intracranial hemorrhage 1 Asymptomatic; clinical or N/A
Intracranial hemorrhage 2 Moderate symptoms; interN/A
Intracranial hemorrhage 3 Ventriculostomy, ICP monitoN/A
Intracranial hemorrhage 4 Life-threatening consequen N/A
Intracranial hemorrhage 5 Death N/A
Intracranial hemorrhage Definition A disorder characterized bN/A
Ischemia cerebrovascular 1 Asymptomatic; clinical or N/A
Ischemia cerebrovascular 2 Moderate symptoms N/A
Ischemia cerebrovascular Definition A disorder characterized bN/A
Trochlear nerve disorder 1 Asymptomatic; clinical or N/A
Trochlear nerve disorder 2 Moderate symptoms; limitN/A
Trochlear nerve disorder 3 Severe symptoms; limitingN/A
Trochlear nerve disorder Definition A disorder characterized byN/A
Lethargy 1 Mild symptoms; reduced aN/A
Lethargy 2 Moderate symptoms; limitN/A
Lethargy Definition A disorder characterized bN/A
Leukoencephalopathy 1 Asymptomatic; small focalN/A
Leukoencephalopathy 2 Moderate symptoms; focalN/A
Leukoencephalopathy 3 Severe symptoms; extensive N/A
Leukoencephalopathy 4 Life-threatening consequen N/A
Leukoencephalopathy 5 Death N/A
Leukoencephalopathy Definition A disorder characterized byN/A
Memory impairment 1 Mild memory impairment N/A
Memory impairment 2 Moderate memory impairme N/A
Memory impairment 3 Severe memory impairment; N/A
Memory impairment Definition A disorder characterized bN/A
Meningismus 1 Mild symptoms N/A
Meningismus 2 Moderate symptoms; limitN/A
Meningismus 3 Severe symptoms; limitingN/A
Meningismus 4 Life-threatening consequen N/A
Meningismus 5 Death N/A
Meningismus Definition A disorder characterized bN/A
Movements involuntary 1 Mild symptoms N/A
Movements involuntary 2 Moderate symptoms; limitN/A
Movements involuntary 3 Severe symptoms; limitingN/A
Movements involuntary Definition A disorder characterized N/A
Myelitis 1 Asymptomatic; mild signs N/A
(e
Myelitis 2 Moderate weakness or sens N/A
Myelitis 3 Severe weakness or sensory N/A
Myelitis 4 Life-threatening consequen N/A
Myelitis 5 Death N/A
Myelitis Definition A disorder characterized bN/A
Nervous system disorders 1- Asymptomatic or mild sympt N/A
Nervous system disorders 2- Moderate; minimal, local oN/A
Nervous system disorders 3- Severe or medically signifiN/A
Nervous system disorders 4- Life-threatening consequen N/A
Nervous system disorders 5- Death N/A
Neuralgia 1 Mild pain N/A
Neuralgia 2 Moderate pain; limiting i N/A
Neuralgia 3 Severe pain; limiting self N/A
Neuralgia Definition A disorder characterized bN/A
Nystagmus 2 Moderate symptoms; limitN/A
Nystagmus 3 Severe symptoms; limitingN/A
Nystagmus Definition A disorder characterized N/A
Oculomotor nerve disorde1 Asymptomatic; clinical or N/A
Oculomotor nerve disorde2 Moderate symptoms; limitN/A
Oculomotor nerve disorde3 Severe symptoms; limitingN/A
Oculomotor nerve disordeDefinition A disorder characterized bN/A
Olfactory nerve disorder 2 Moderate symptoms; limitN/A
Olfactory nerve disorder 3 Severe symptoms; limitingN/A
Olfactory nerve disorder Definition A disorder characterized byN/A
Paresthesia 1 Mild symptoms N/A
Paresthesia 2 Moderate symptoms; limitN/A
Paresthesia 3 Severe symptoms; limitingN/A
Paresthesia Definition A disorder characterized bN/A
Peripheral motor neuropa1 Asymptomatic; clinical or N/A
Peripheral motor neuropa2 Moderate symptoms; limitN/A
Peripheral motor neuropa3 Severe symptoms; limitingN/A
Peripheral motor neuropa4 Life-threatening consequen N/A
Peripheral motor neuropa5 Death N/A
Peripheral motor neuropaDefinition A disorder characterized N/A
Peripheral sensory neurop1 Asymptomatic N/A
Peripheral sensory neurop2 Moderate symptoms; limitN/A
Peripheral sensory neurop3 Severe symptoms; limitingN/A
Peripheral sensory neurop4 Life-threatening consequen N/A
Peripheral sensory neuropDefinition A disorder characterized bN/A
Nervous system disorders 5- Death Peripheral sensory neuropathy
Phantom pain 1 Mild pain N/A
Phantom pain 2 Moderate pain; limiting i N/A
Phantom pain 3 Severe pain; limiting self N/A
Phantom pain Definition A disorder characterized bN/A
Presyncope 2 Present (e.g., near faintingN/A
Presyncope Definition A disorder characterized N/A
Pyramidal tract syndrome 1 Asymptomatic; clinical or N/A
Pyramidal tract syndrome 2 Moderate symptoms; limitN/A
Pyramidal tract syndrome 3 Severe symptoms; limitingN/A
Pyramidal tract syndrome 4 Life-threatening consequen N/A
Pyramidal tract syndrome 5 Death N/A
Pyramidal tract syndrome Definition A disorder characterized bN/A
Radiculitis 1 Mild symptoms N/A
Radiculitis 2 Moderate symptoms; medica N/A
Radiculitis 3 Severe symptoms; limitingN/A
Radiculitis 4 Life-threatening consequen N/A
Radiculitis 5 Death N/A
Radiculitis Definition A disorder characterized bN/A
Recurrent laryngeal nerve 1 Asymptomatic; clinical or N/A
Recurrent laryngeal nerve 2 Moderate symptoms N/A
Recurrent laryngeal nerve 3 Severe symptoms; medicalN/A i
Recurrent laryngeal nerve 4 Life-threatening consequen N/A
Recurrent laryngeal nerve 5 Death N/A
Recurrent laryngeal nerve Definition A disorder characterized by N/A
Nervous system disorders 1- Asymptomatic or mild sympt Reversible posterior leukoencephalopathy syndrom
Reversible posterior leu 2 Moderate symptoms; limitN/A
Reversible posterior leu 3 Severe symptoms; limitingN/A
Reversible posterior leu 4 Life-threatening consequeN/A
Reversible posterior leu 5 Death N/A
Reversible posterior leu Definition A disorder characterized bN/A
Seizure 1 Brief partial seizure and n N/A
Seizure 2 Brief generalized seizure N/A
Seizure 3 New onset seizures (partiaN/A
Seizure 4 Life-threatening consequen N/A
Seizure 5 Death N/A
Seizure Definition A disorder characterized bN/A
Sinus pain 1 Mild pain N/A
Sinus pain 2 Moderate pain; limiting i N/A
Sinus pain 3 Severe pain; limiting self N/A
Sinus pain Definition A disorder characterized bN/A
Somnolence 1 Mild but more than usual N/A
Somnolence 2 Moderate sedation; limiti N/A
Somnolence 3 Obtundation or stupor N/A
Somnolence 4 Life-threatening consequen N/A
Somnolence 5 Death N/A
Somnolence Definition A disorder characterized bN/A
Spasticity 1 Mild or slight increase in N/A
Spasticity 2 Moderate increase in muscN/A
Spasticity 3 Severe increase in muscle N/A
Spasticity 4 Life-threatening consequeN/A
Spasticity 5 Death N/A
Spasticity Definition A disorder characterized bN/A
Stroke 1 Incidental radiographic finN/A
Stroke 2 Mild to moderate neurologi N/A
Stroke 3 Severe neurologic deficit; N/A
Stroke 4 Life-threatening consequen N/A
Stroke 5 Death N/A
Stroke Definition A disorder characterized bN/A
Syncope 3 Fainting; orthostatic colla N/A
Syncope Definition A disorder characterized bN/A
Transient ischemic attacks1 Mild neurologic deficit wi N/A
Transient ischemic attacks2 Moderate neurologic deficN/A
Transient ischemic attacksDefinition A disorder characterized by N/A
Tremor 1 Mild symptoms N/A
Tremor 2 Moderate symptoms; limitN/A
Tremor 3 Severe symptoms; limitingN/A
Tremor Definition A disorder characterized bN/A
Trigeminal nerve disorder 1 Asymptomatic; clinical or N/A
Trigeminal nerve disorder 2 Moderate symptoms; limitN/A
Trigeminal nerve disorder 3 Severe symptoms; limitingN/A
Trigeminal nerve disorder Definition A disorder characterized by N/A
Vagus nerve disorder 1 Asymptomatic; clinical or N/A
Vagus nerve disorder 2 Moderate symptoms; limitN/A
Vagus nerve disorder 3 Severe symptoms; limitingN/A
Vagus nerve disorder 4 Life-threatening consequen N/A
Vagus nerve disorder 5 Death N/A
Vagus nerve disorder Definition A disorder characterized bN/A
Vasovagal reaction 3 Present N/A
Vasovagal reaction 4 Life-threatening consequen N/A
Vasovagal reaction 5 Death N/A
Vasovagal reaction Definition A disorder characterized bN/A
Pregnancy loss 4 Fetal loss at any gestationN/A
Pregnancy loss Definition Death in utero. N/A
Fetal growth retardation 2 <10% percentile of weightN/A
Fetal growth retardation 3 <5% percentile of weight fN/A
Fetal growth retardation 4 <1% percentile of weight fN/A
Fetal growth retardation Definition A disorder characterized by N/A
Pregnancy, puerperium and 1 Asymptomatic or mild sympt N/A
Pregnancy, puerperium and 2 Moderate; minimal, local oN/A
Pregnancy, puerperium and 3 Severe or medically signifiN/A
Pregnancy, puerperium and 4 Life-threatening consequen N/A
Pregnancy, puerperium and 5 Death N/A
Premature delivery 1 Delivery of a liveborn infa N/A
Premature delivery Definition A disorder characterized by N/A
Pregnancy, puerperium and 3 Severe or medically signifiUnintended pregnancy
Pregnancy, puerperium and Definition - N/A
Agitation 1 Mild mood alteration N/A
Agitation 2 Moderate mood alteratio N/A
Agitation 3 Severe agitation; hospitaliN/A
Agitation 4 Life-threatening consequen N/A
Agitation Definition A disorder characterized by N/A
Psychiatric disorders - Oth5 Death Agitation
Anorgasmia 1 Inability to achieve orgasmN/A
Anorgasmia 2 Inability to achieve orgasmN/A
Anorgasmia Definition A disorder characterized bN/A
Anxiety 1 Mild symptoms; interventiN/A
Anxiety 2 Moderate symptoms; limitN/A
Anxiety 3 Severe symptoms; limitingN/A
Anxiety 4 Life-threatening consequen N/A
Anxiety Definition A disorder characterized bN/A
Psychiatric disorders - Oth5 Death Anxiety
Psychiatric disorders - Oth5 Death Confusion
Confusion 1 Mild disorientation N/A
Confusion 2 Moderate disorientation; lN/A
Confusion 3 Severe disorientation; limiN/A
Confusion 4 Life-threatening consequen N/A
Confusion Definition A disorder characterized bN/A
Delayed orgasm 1 Delay in achieving orgasm N/A
Delayed orgasm 2 Delay in achieving orgasm N/A
Delayed orgasm Definition A disorder characterized bN/A
Delirium 1 Mild acute confusional staN/A
Delirium 2 Moderate and acute confus N/A
Delirium 3 Severe and acute confusion N/A
Delirium 4 Life-threatening consequen N/A
Delirium 5 Death N/A
Delirium Definition A disorder characterized bN/A
Delusions 2 Moderate delusional sym N/A
Delusions 3 Severe delusional symptom N/A
Delusions 4 Life-threatening consequen N/A
Delusions 5 Death N/A
Delusions Definition A disorder characterized bN/A
Depression 1 Mild depressive symptom N/A
Depression 2 Moderate depressive sympN/A
Depression 3 Severe depressive symptoms N/A
Depression 4 Life-threatening consequen N/A
Depression 5 Death N/A
Depression Definition A disorder characterized bN/A
Euphoria 1 Mild mood elevation N/A
Euphoria 2 Moderate mood elevationN/A
Euphoria 3 Severe mood elevation (e.N/A
Euphoria Definition A disorder characterized bN/A
Hallucinations 1 Mild hallucinations (e.g., N/A
Hallucinations 2 Moderate hallucinations N/A
Hallucinations 3 Severe hallucinations; hospN/A
Hallucinations 4 Life-threatening consequen N/A
Hallucinations 5 Death N/A
Hallucinations Definition A disorder characterized bN/A
Insomnia 1 Mild difficulty falling asl N/A
Insomnia 2 Moderate difficulty fallingN/A
Insomnia 3 Severe difficulty in falling N/A
Insomnia Definition A disorder characterized by N/A
Libido decreased 1 Decrease in sexual interestN/A
Libido decreased 2 Decrease in sexual interestN/A
Libido decreased Definition A disorder characterized bN/A
Libido increased 1 Present N/A
Libido increased Definition A disorder characterized by N/A
Mania 1 Mild manic symptoms (e.g.N/A
Mania 2 Moderate manic symptoms N/A
(e
Mania 3 Severe manic symptoms (e.g N/A
Mania 4 Life-threatening consequen N/A
Mania 5 Death N/A
Mania Definition A disorder characterized bN/A
Personality change 1 Mild personality change N/A
Personality change 2 Moderate personality cha N/A
Personality change 3 Severe personality change;N/A
Personality change 4 Life-threatening consequen N/A
Personality change Definition A disorder characterized bN/A
Psychiatric disorders - Oth5 Death Personality change
Psychiatric disorders - Oth1 Asymptomatic or mild sympt N/A
Psychiatric disorders - Oth2 Moderate; minimal, local oN/A
Psychiatric disorders - Oth3 Severe or medically signifiN/A
Psychiatric disorders - Oth4 Life-threatening consequen N/A
Psychiatric disorders - Oth5 Death N/A
Psychosis 1 Mild psychotic symptoms N/A
Psychosis 2 Moderate psychotic symptom N/A
Psychosis 3 Severe psychotic symptoms N/A
Psychosis 4 Life-threatening consequen N/A
Psychosis 5 Death N/A
Psychosis Definition A disorder characterized bN/A
Restlessness 1 Mild symptoms; interventiN/A
Restlessness 2 Moderate symptoms; limitN/A
Restlessness 3 Severe symptoms; limitingN/A
Restlessness Definition A disorder characterized by N/A
Suicidal ideation 1 Increased thoughts of deatN/A
Suicidal ideation 2 Suicidal ideation with no sN/A
Suicidal ideation 3 Specific plan to commit suN/A
Suicidal ideation 4 Specific plan to commit suiN/A
Suicidal ideation Definition A disorder characterized bN/A
Suicide attempt 3 Suicide attempt or gestureN/A
Suicide attempt 4 Suicide attempt with intenN/A
Suicide attempt 5 Death N/A
Suicide attempt Definition A disorder characterized by N/A
Acute kidney injury 3 Hospitalization indicated N/A
Acute kidney injury 4 Life-threatening consequen N/A
Acute kidney injury 5 Death N/A
Acute kidney injury Definition A disorder characterized by N/A
Bladder perforation 2 Invasive intervention not N/A
Bladder perforation 3 Invasive intervention indi N/A
Bladder perforation 4 Life-threatening consequen N/A
Bladder perforation 5 Death N/A
Bladder perforation Definition A disorder characterized bN/A
Bladder spasm 1 Intervention not indicatedN/A
Bladder spasm 2 Antispasmodics indicated N/A
Bladder spasm 3 Hospitalization indicated N/A
Bladder spasm Definition A disorder characterized bN/A
Chronic kidney disease 1 eGFR (estimated Glomerular N/A
Chronic kidney disease 2 eGFR or CrCl 59 - 30 ml/mN/A
Chronic kidney disease 3 eGFR or CrCl 29 - 15 ml/mN/A
Chronic kidney disease 4 eGFR or CrCl <15 ml/min/1. N/A
Chronic kidney disease 5 Death N/A
Chronic kidney disease Definition A disorder characterized by N/A
Cystitis noninfective 1 Microscopic hematuria; min N/A
Cystitis noninfective 2 Moderate hematuria; modera N/A
Cystitis noninfective 3 Gross hematuria; transfusio N/A
Cystitis noninfective 4 Life-threatening consequen N/A
Cystitis noninfective 5 Death N/A
Cystitis noninfective Definition A disorder characterized bN/A
Hematuria 1 Asymptomatic; clinical or N/A
Hematuria 2 Symptomatic; urinary cathe N/A
Hematuria 3 Gross hematuria; transfusioN/A
Hematuria 4 Life-threatening consequen N/A
Hematuria 5 Death N/A
Hematuria Definition A disorder characterized byN/A
Hemoglobinuria 1 Asymptomatic; clinical or N/A
Hemoglobinuria Definition A disorder characterized bN/A
Proteinuria 1 1+ proteinuria; urinary pr N/A
Proteinuria 2 Pediatric: urine P/C (Protein/Creatinine)
N/A ratio 0.5 - 1.9
Proteinuria 3 Pediatric: urine P/C (Protein/Creatinine)
N/A ratio >1.9
Proteinuria Definition A disorder characterized byN/A
Renal and urinary disorder1 Asymptomatic or mild sympt N/A
Renal and urinary disorder2 Moderate; minimal, local oN/A
Renal and urinary disorder3 Severe or medically signifiN/A
Renal and urinary disorder4 Life-threatening consequen N/A
Renal and urinary disorder5 Death N/A
Renal calculi 1 Asymptomatic or mild symp N/A
Renal calculi 2 Symptomatic; oral antiemet N/A
Renal calculi 3 Hospitalization indicated; N/A
Renal calculi 4 Life-threatening consequen N/A
Renal calculi 5 Death N/A
Renal calculi Definition A disorder characterized byN/A
Renal colic 1 Mild pain not interfering N/A
Renal colic 2 Moderate pain; limiting inN/A
Renal colic 3 Hospitalization indicated; N/A
Renal colic Definition A disorder characterized bN/A
Renal hemorrhage 1 Mild symptoms; interventiN/A
Renal hemorrhage 2 Analgesics and hematocritN/A
Renal hemorrhage 3 Transfusion indicated; invaN/A
Renal hemorrhage 4 Life-threatening consequen N/A
Renal hemorrhage 5 Death N/A
Renal hemorrhage Definition A disorder characterized bN/A
Urinary fistula 2 Symptomatic, invasive inteN/A
Urinary fistula 3 Invasive intervention indi N/A
Urinary fistula 4 Life-threatening consequen N/A
Urinary fistula 5 Death N/A
Urinary fistula Definition A disorder characterized N/A
Urinary frequency 1 Present N/A
Urinary frequency 2 Limiting instrumental ADLN/A
Urinary frequency Definition A disorder characterized byN/A
Urinary incontinence 1 Occasional (e.g., with cougN/A
Urinary incontinence 2 Spontaneous; pads indicatN/A
Urinary incontinence 3 Intervention indicated (e.gN/A
Urinary incontinence Definition A disorder characterized byN/A
Urinary retention 1 Urinary, suprapubic or int N/A
Urinary retention 2 Placement of urinary, suprN/A
Urinary retention 3 Elective invasive interventN/A
Urinary retention 4 Life-threatening consequen N/A
Urinary retention 5 Death N/A
Urinary retention Definition A disorder characterized bN/A
Urinary tract obstruction 1 Asymptomatic; clinical or N/A
Urinary tract obstruction 2 Symptomatic but no hydrone N/A
Urinary tract obstruction 3 Altered organ function (e. N/A
Urinary tract obstruction 4 Life-threatening consequen N/A
Urinary tract obstruction 5 Death N/A
Urinary tract obstruction Definition A disorder characterized bN/A
Urinary tract pain 1 Mild pain N/A
Urinary tract pain 2 Moderate pain; limiting i N/A
Urinary tract pain 3 Severe pain; limiting self N/A
Urinary tract pain Definition A disorder characterized bN/A
Urinary urgency 1 Present N/A
Urinary urgency 2 Limiting instrumental ADLN/A
Urinary urgency Definition A disorder characterized bN/A
Urine discoloration 1 Present N/A
Urine discoloration Definition A disorder characterized byN/A
Azoospermia 2 Absence of sperm in ejacuN/A
Azoospermia Definition A disorder characterized bN/A
Breast atrophy 1 Minimal asymmetry; minim N/A
Breast atrophy 2 Moderate asymmetry; mod N/A
Breast atrophy 3 Asymmetry >1/3 of breastN/A
Breast atrophy Definition A disorder characterized N/A
Breast pain 1 Mild pain N/A
Breast pain 2 Moderate pain; limiting i N/A
Breast pain 3 Severe pain; limiting self N/A
Breast pain Definition A disorder characterized bN/A
Dysmenorrhea 1 Mild symptoms; interventiN/A
Dysmenorrhea 2 Moderate symptoms; limitN/A
Dysmenorrhea 3 Severe symptoms; limitingN/A
Dysmenorrhea Definition A disorder characterized N/A
Dyspareunia 1 Mild discomfort or pain asN/A
Dyspareunia 2 Moderate discomfort or pai N/A
Dyspareunia 3 Severe discomfort or pain N/A
Dyspareunia Definition A disorder characterized byN/A
Ejaculation disorder 1 Diminished ejaculation N/A
Ejaculation disorder 2 Anejaculation or retrogradN/A
Ejaculation disorder Definition A disorder characterized bN/A
Erectile dysfunction 1 Decrease in erectile functiN/A
Erectile dysfunction 2 Decrease in erectile functiN/A
Erectile dysfunction 3 Decrease in erectile funct N/A
Erectile dysfunction Definition A disorder characterized byN/A
Fallopian tube obstruction1 Asymptomatic; clinical or N/A
Fallopian tube obstruction2 Symptomatic; elective inteN/A
Fallopian tube obstruction3 Severe symptoms; invasiveN/A
Fallopian tube obstructionDefinition A disorder characterized bN/A
Reproductive system and br1 Asymptomatic or mild sympt Fallopian tube stenosis
Reproductive system and br2 Moderate; minimal, local oFallopian tube stenosis
Reproductive system and br3 Severe or medically signifiFallopian tube stenosis
Reproductive system and br4 Life-threatening consequen Fallopian tube stenosis
Reproductive system and br5 Death Fallopian tube stenosis
Reproductive system and brDefinition - N/A
Reproductive system and br1 Asymptomatic or mild sympt Female genital tract fistula
Reproductive system and br2 Moderate; minimal, local oFemale genital tract fistula
Reproductive system and br3 Severe or medically signifiFemale genital tract fistula
Reproductive system and br4 Life-threatening consequen Female genital tract fistula
Reproductive system and br5 Death Female genital tract fistula
Reproductive system and brDefinition - N/A
Feminization acquired 1 Mild symptoms; interventiN/A
Feminization acquired 2 Moderate symptoms; medic N/A
Feminization acquired Definition A disorder characterized bN/A
Genital edema 1 Mild swelling or obscurati N/A
Genital edema 2 Readily apparent obscuratiN/A
Genital edema 3 Lymphorrhea; gross deviatN/A
Genital edema Definition A disorder characterized byN/A
Gynecomastia 1 Asymptomatic N/A
Gynecomastia 2 Symptomatic (e.g., pain orN/A
Gynecomastia 3 Severe symptoms; electiveN/A
Gynecomastia Definition A disorder characterized bN/A
Hematosalpinx 1 Minimal bleeding identifieN/A
Hematosalpinx 2 Moderate bleeding; medica N/A
Hematosalpinx 3 Transfusion indicated; inv N/A
Hematosalpinx 4 Life-threatening consequen N/A
Hematosalpinx 5 Death N/A
Hematosalpinx Definition A disorder characterized bN/A
Irregular menstruation 1 Intermittent/irregular menses
N/A for no more than 3 consecutive menstrual cyc
Irregular menstruation 2 Intermittent/irregular menses
N/A for more than 3 consecutive menstrual cycles
Irregular menstruation Definition A disorder characterized bN/A
Amenorrhea 2 Present N/A
Lactation disorder 1 Mild changes in lactation, N/A
Lactation disorder 2 Changes in lactation, signiN/A
Lactation disorder Definition A disorder characterized bN/A
Menorrhagia 1 Mild; iron supplements in N/A
Menorrhagia 2 Moderate symptoms; medica N/A
Menorrhagia 3 Severe; transfusion indica N/A
Menorrhagia 4 Life-threatening consequen N/A
Menorrhagia 5 Death N/A
Menorrhagia Definition A disorder characterized N/A
Nipple deformity 1 Asymptomatic; asymmetryN/A w
Nipple deformity 2 Symptomatic; asymmetry N/A of
Nipple deformity Definition A disorder characterized bN/A
Oligospermia 1 Sperm concentration > 0 to N/A
Oligospermia Definition A disorder characterized N/A
Ovarian hemorrhage 1 Mild symptoms; interventiN/A
Ovarian hemorrhage 2 Moderate symptoms; interN/A
Ovarian hemorrhage 3 Transfusion indicated; invaN/A
Ovarian hemorrhage 4 Life-threatening consequen N/A
Ovarian hemorrhage 5 Death N/A
Ovarian hemorrhage Definition A disorder characterized bN/A
Ovarian rupture 1 Asymptomatic clinical or dN/A
Ovarian rupture 2 Symptomatic and interventN/A
Ovarian rupture 3 Transfusion; invasive inte N/A
Ovarian rupture 4 Life-threatening consequen N/A
Ovarian rupture 5 Death N/A
Ovarian rupture Definition A disorder characterized byN/A
Ovulation pain 2 Present N/A
Ovulation pain Definition A disorder characterized bN/A
Reproductive system and br4 Life-threatening consequen Pelvic floor muscle weakness
Reproductive system and br5 Death Pelvic floor muscle weakness
Pelvic floor muscle weakn 1 Asymptomatic; clinical or N/A
Pelvic floor muscle weakn 2 Symptomatic, not interferiN/A
Pelvic floor muscle weakn 3 Severe symptoms; limitingN/A
Pelvic floor muscle weakn Definition A disorder characterized byN/A
Pelvic pain 1 Mild pain N/A
Pelvic pain 2 Moderate pain; limiting i N/A
Pelvic pain 3 Severe pain; limiting self N/A
Pelvic pain Definition A disorder characterized bN/A
Penile pain 1 Mild pain N/A
Penile pain 2 Moderate pain; limiting i N/A
Penile pain 3 Severe pain; limiting self N/A
Penile pain Definition A disorder characterized bN/A
Perineal pain 1 Mild pain N/A
Perineal pain 2 Moderate pain; limiting i N/A
Perineal pain 3 Severe pain; limiting self N/A
Perineal pain Definition A disorder characterized bN/A
Premature menopause 2 Present N/A
Premature menopause Definition A disorder characterized bN/A
Prostatic hemorrhage 1 Mild symptoms; interventiN/A
Prostatic hemorrhage 2 Moderate symptoms; interN/A
Prostatic hemorrhage 3 Transfusion indicated; invaN/A
Prostatic hemorrhage 4 Life-threatening consequen N/A
Prostatic hemorrhage 5 Death N/A
Prostatic hemorrhage Definition A disorder characterized bN/A
Prostatic obstruction 1 Asymptomatic; clinical or N/A
Prostatic obstruction 2 Symptomatic; elective inteN/A
Prostatic obstruction 3 Severe symptoms; invasiveN/A
Prostatic obstruction Definition A disorder characterized bN/A
Prostatic pain 1 Mild pain N/A
Prostatic pain 2 Moderate pain; limiting i N/A
Prostatic pain 3 Severe pain; limiting self N/A
Prostatic pain Definition A disorder characterized bN/A
Reproductive system and br
5 Death N/A
Scrotal pain 1 Mild pain N/A
Scrotal pain 2 Moderate pain; limiting i N/A
Scrotal pain 3 Severe pain; limiting self N/A
Scrotal pain Definition A disorder characterized bN/A
Spermatic cord hemorrha 1 Mild symptoms; interventiN/A
Spermatic cord hemorrha 2 Moderate symptoms; interN/A
Spermatic cord hemorrha 3 Transfusion indicated; invaN/A
Spermatic cord hemorrha 4 Life-threatening consequen N/A
Spermatic cord hemorrha 5 Death N/A
Spermatic cord hemorrha Definition A disorder characterized bN/A
Spermatic cord obstructio1 Asymptomatic; clinical or N/A
Spermatic cord obstructio2 Symptomatic; elective inteN/A
Spermatic cord obstructio3 Severe symptoms; invasiveN/A
Spermatic cord obstructioDefinition A disorder characterized bN/A
5 Death Testicular disorder
Testicular disorder 1 Asymptomatic; clinical or N/A
Testicular disorder 2 Symptomatic but not interfN/A
Testicular disorder 3 Severe symptoms; interferiN/A
Testicular disorder 4 Life-threatening consequen N/A
Testicular disorder Definition A disorder characterized bN/A
Testicular hemorrhage 1 Mild symptoms; interventiN/A
Testicular hemorrhage 2 Moderate symptoms; interN/A
Testicular hemorrhage 3 Transfusion indicated; invaN/A
Testicular hemorrhage 4 Life-threatening consequen N/A
Testicular hemorrhage 5 Death N/A
Testicular hemorrhage Definition A disorder characterized bN/A
Testicular pain 1 Mild pain N/A
Testicular pain 2 Moderate pain; limiting i N/A
Testicular pain 3 Severe pain; limiting self N/A
Testicular pain Definition A disorder characterized bN/A
Uterine fistula 1 Asymptomatic N/A
Uterine fistula 2 Symptomatic, invasive inteN/A
Uterine fistula 3 Invasive intervention indi N/A
Uterine fistula 4 Life-threatening consequen N/A
Uterine fistula 5 Death N/A
Uterine fistula Definition A disorder characterized N/A
Uterine hemorrhage 1 Mild symptoms; interventiN/A
Uterine hemorrhage 2 Moderate symptoms; interN/A
Uterine hemorrhage 3 Transfusion indicated; invaN/A
Uterine hemorrhage 4 Life-threatening consequen N/A
Uterine hemorrhage 5 Death N/A
Uterine hemorrhage Definition A disorder characterized bN/A
Uterine obstruction 1 Asymptomatic; clinical or N/A
Uterine obstruction 2 Symptomatic; elective inteN/A
Uterine obstruction 3 Severe symptoms; invasiveN/A
Uterine obstruction Definition A disorder characterized bN/A
Uterine pain 1 Mild pain N/A
Uterine pain 2 Moderate pain; limiting i N/A
Uterine pain 3 Severe pain; limiting self N/A
Uterine pain Definition A disorder characterized bN/A
Vaginal discharge 1 Mild vaginal discharge (greN/A
Vaginal discharge 2 Moderate to heavy vaginalN/A
Vaginal discharge Definition A disorder characterized bN/A
Vaginal dryness 1 Mild vaginal dryness not i N/A
Vaginal dryness 2 Moderate vaginal dryness N/A
i
Vaginal dryness 3 Severe vaginal dryness resN/A
Vaginal dryness Definition A disorder characterized bN/A
Vaginal fistula 1 Asymptomatic N/A
Vaginal fistula 2 Symptomatic, invasive inteN/A
Vaginal fistula 3 Invasive intervention indi N/A
Vaginal fistula 4 Life-threatening consequen N/A
Vaginal fistula 5 Death N/A
Vaginal fistula Definition A disorder characterized N/A
Vaginal hemorrhage 1 Mild symptoms; interventiN/A
Vaginal hemorrhage 2 Moderate symptoms; interN/A
Vaginal hemorrhage 3 Transfusion indicated; invaN/A
Vaginal hemorrhage 4 Life-threatening consequen N/A
Vaginal hemorrhage 5 Death N/A
Vaginal hemorrhage Definition A disorder characterized bN/A
Reproductive system and br 5 Death Vaginal inflammation
Vaginal inflammation 1 Mild discomfort or pain, N/A
Vaginal inflammation 2 Moderate discomfort or paN/A
Vaginal inflammation 3 Severe discomfort or pain,N/A
Vaginal inflammation 4 Life-threatening consequeN/A
Vaginal inflammation Definition A disorder characterized N/A
Vaginal obstruction 1 Asymptomatic; clinical or N/A
Vaginal obstruction 2 Symptomatic; elective inteN/A
Vaginal obstruction 3 Severe symptoms; invasiveN/A
Vaginal obstruction Definition A disorder characterized bN/A
Vaginal pain 1 Mild pain N/A
Vaginal pain 2 Moderate pain; limiting i N/A
Vaginal pain 3 Severe pain; limiting self N/A
Vaginal pain Definition A disorder characterized bN/A
Reproductive system and br 1 Asymptomatic or mild sympt Vaginal perforation
Vaginal perforation 2 Invasive intervention not N/A
Vaginal perforation 3 Invasive intervention indi N/A
Vaginal perforation 4 Life-threatening consequen N/A
Vaginal perforation 5 Death N/A
Vaginal perforation Definition A disorder characterized byN/A
Vaginal stricture 1 Asymptomatic; mild vaginaN/A
Vaginal stricture 2 Vaginal narrowing and/or N s /A
Vaginal stricture 3 Vaginal narrowing and/or N s /A
Vaginal stricture 5 Death N/A
Vaginal stricture Definition A disorder characterized bN/A
Reproductive system and br 1 Asymptomatic or mild sympt Vaginismus
Reproductive system and br 2 Moderate; minimal, local oVaginismus
Reproductive system and br 3 Severe or medically signifiVaginismus
Reproductive system and br Definition - N/A
Adult respiratory distress 3 Present with radiologic finN/A
Adult respiratory distress 4 Life-threatening respirat N/A
Adult respiratory distress 5 Death N/A
Adult respiratory distress Definition A disorder characterized bN/A
Allergic rhinitis 1 Mild symptoms; interventiN/A
Allergic rhinitis 2 Moderate symptoms; medic N/A
Allergic rhinitis Definition A disorder characterized N/A
Apnea 3 Present; medical interventN/A
Apnea 4 Life-threatening respirat N/A
Apnea 5 Death N/A
Apnea Definition A disorder characterized bN/A
Aspiration 1 Asymptomatic; clinical or N/A
Aspiration 2 Altered eating habits; cou N/A
Aspiration 3 Dyspnea and pneumonia sym N/A
Aspiration 4 Life-threatening respirat N/A
Aspiration 5 Death N/A
Aspiration Definition A disorder characterized by N/A
Atelectasis 1 Asymptomatic; clinical or N/A
Atelectasis 2 Symptomatic (e.g., dyspnea N/A
Atelectasis 3 Supplemental oxygen indicat N/A
Atelectasis 4 Life-threatening respirat N/A
Atelectasis 5 Death N/A
Atelectasis Definition A disorder characterized by N/A
Bronchial fistula 1 Asymptomatic N/A
Bronchial fistula 2 Symptomatic, invasive inteN/A
Bronchial fistula 3 Invasive intervention indi N/A
Bronchial fistula 4 Life-threatening consequen N/A
Bronchial fistula 5 Death N/A
Bronchial fistula Definition A disorder characterized N/A
Bronchial obstruction 1 Asymptomatic; clinical or N/A
Bronchial obstruction 2 Symptomatic (e.g., mild whN/A
Bronchial obstruction 3 Shortness of breath with stN/A
Bronchial obstruction 4 Life-threatening respirat N/A
Bronchial obstruction 5 Death N/A
Bronchial obstruction Definition A disorder characterized bN/A
Bronchial stricture 1 Asymptomatic; clinical or N/A
Bronchial stricture 2 Symptomatic (e.g., rhonchiN/A
Bronchial stricture 3 Shortness of breath with stN/A
Bronchial stricture 4 Life-threatening respirat N/A
Bronchial stricture 5 Death N/A
Bronchial stricture Definition A disorder characterized bN/A
Bronchopleural fistula 1 Asymptomatic N/A
Bronchopleural fistula 2 Symptomatic, invasive inteN/A
Bronchopleural fistula 3 Hospitalization; invasive i N/A
Bronchopleural fistula 4 Life-threatening consequen N/A
Bronchopleural fistula 5 Death N/A
Bronchopleural fistula Definition A disorder characterized N/A
Bronchopulmonary hemor1 Mild symptoms; interventiN/A
Bronchopulmonary hemor2 Moderate symptoms; invasi N/A
Bronchopulmonary hemor3 Transfusion indicated; invaN/A
Bronchopulmonary hemor4 Life-threatening consequen N/A
Bronchopulmonary hemor5 Death N/A
Bronchopulmonary hemorDefinition A disorder characterized N/A
Bronchospasm 1 Mild symptoms; interventiN/A
Bronchospasm 2 Symptomatic; medical inter N/A
Bronchospasm 3 Limiting self care ADL; su N/A
Bronchospasm 4 Life-threatening respirat N/A
Bronchospasm 5 Death N/A
Bronchospasm Definition A disorder characterized bN/A
Chylothorax 1 Asymptomatic; clinical or N/A
Chylothorax 2 Symptomatic; medical inter N/A
Chylothorax 3 Severe symptoms; electiveN/A
Chylothorax 4 Life-threatening respirat N/A
Chylothorax 5 Death N/A
Chylothorax Definition A disorder characterized by N/A
Cough 1 Mild symptoms; nonprescri N/A
Cough 2 Moderate symptoms, medica N/A
Cough 3 Severe symptoms; limitingN/A
Cough Definition A disorder characterized by N/A
Dyspnea 1 Shortness of breath with N/A
Dyspnea 2 Shortness of breath with mN/A
Dyspnea 3 Shortness of breath at restN/A
Dyspnea 4 Life-threatening consequen N/A
Dyspnea 5 Death N/A
Dyspnea Definition A disorder characterized bN/A
Epistaxis 1 Mild symptoms; interventiN/A
Epistaxis 2 Moderate symptoms; medical N/A
Epistaxis 3 Transfusion; invasive interN/A
Epistaxis 4 Life-threatening consequen N/A
Epistaxis 5 Death N/A
Epistaxis Definition A disorder characterized bN/A
Hiccups 1 Mild symptoms; interventiN/A
Hiccups 2 Moderate symptoms; medica N/A
Hiccups 3 Severe symptoms; interferiN/A
Hiccups Definition A disorder characterized bN/A
Hoarseness 1 Mild or intermittent voice N/A
Hoarseness 2 Moderate or persistent voN/A
Hoarseness 3 Severe voice changes incl N/A
Hoarseness Definition A disorder characterized bN/A
Hypoxia 2 Decreased oxygen saturatiN/A
Hypoxia 3 Decreased oxygen saturatiN/A
Hypoxia 4 Life-threatening airway coN/A
Hypoxia 5 Death N/A
Hypoxia Definition A disorder characterized bN/A
Laryngeal edema 1 Asymptomatic; clinical or N/A
Laryngeal edema 2 Symptomatic; medical inteN/A
Laryngeal edema 3 Stridor; respiratory distresN/A
Laryngeal edema 4 Life-threatening airway coN/A
Laryngeal edema 5 Death N/A
Laryngeal edema Definition A disorder characterized by N/A
Laryngeal fistula 1 Asymptomatic N/A
Laryngeal fistula 2 Symptomatic, invasive inteN/A
Laryngeal fistula 3 Invasive intervention indi N/A
Laryngeal fistula 4 Life-threatening consequen N/A
Laryngeal fistula 5 Death N/A
Laryngeal fistula Definition A disorder characterized N/A
Laryngeal hemorrhage 1 Mild cough or trace hemopt N/A
Laryngeal hemorrhage 2 Moderate symptoms; interN/A
Laryngeal hemorrhage 3 Transfusion indicated; invaN/A
Laryngeal hemorrhage 4 Life-threatening consequen N/A
Laryngeal hemorrhage 5 Death N/A
Laryngeal hemorrhage Definition A disorder characterized bN/A
Laryngeal inflammation 1 Mild sore throat; raspy vo N/A
Laryngeal inflammation 2 Moderate sore throat; analN/A
Laryngeal inflammation 3 Severe throat pain; endoscN/A
Laryngeal inflammation Definition A disorder characterized bN/A
Laryngeal mucositis 1 Endoscopic findings only; N/A
Laryngeal mucositis 2 Moderate pain, analgesicsN/A
Laryngeal mucositis 3 Severe pain; severely alte N/A
Laryngeal mucositis 4 Life-threatening airway coN/A
Laryngeal mucositis 5 Death N/A
Laryngeal mucositis Definition A disorder characterized N/A
Laryngeal obstruction 1 Asymptomatic; clinical or N/A
Laryngeal obstruction 2 Symptomatic (e.g., noisy aiN/A
Laryngeal obstruction 3 Limiting self care ADL; stri N/A
Laryngeal obstruction 4 Life-threatening consequen N/A
Laryngeal obstruction 5 Death N/A
Laryngeal obstruction Definition A disorder characterized bN/A
Laryngeal stenosis 1 Asymptomatic; clinical or N/A
Laryngeal stenosis 2 Symptomatic (e.g., noisy aiN/A
Laryngeal stenosis 3 Limiting self care ADL; stri N/A
Laryngeal stenosis 4 Life-threatening consequen N/A
Laryngeal stenosis 5 Death N/A
Laryngeal stenosis Definition A disorder characterized bN/A
Laryngopharyngeal dysest1 Mild symptoms; no anxietyN/A
Laryngopharyngeal dysest2 Moderate symptoms; mildN/A an
Laryngopharyngeal dysest3 Severe symptoms; dyspneaN/A a
Laryngopharyngeal dysest4 Life-threatening consequeN/A
Laryngopharyngeal dysest5 Death N/A
Laryngopharyngeal dysestDefinition A disorder characterized bN/A
Laryngospasm 2 Transient episode; interveN/A
Laryngospasm 3 Recurrent episodes; noninv N/A
Laryngospasm 4 Persistent or severe episodN/A
Laryngospasm 5 Death N/A
Laryngospasm Definition A disorder characterized N/A
Mediastinal hemorrhage 1 Mild symptoms; interventio N/A
Mediastinal hemorrhage 2 Moderate symptoms; interN/A
Mediastinal hemorrhage 3 Transfusion indicated; invaN/A
Mediastinal hemorrhage 4 Life-threatening consequen N/A
Mediastinal hemorrhage 5 Death N/A
Mediastinal hemorrhage Definition A disorder characterized N/A
Nasal congestion 1 Mild symptoms; interventiN/A
Nasal congestion 2 Moderate symptoms; medic N/A
Nasal congestion 3 Associated with bloody nasN/A
Nasal congestion Definition A disorder characterized N/A
Pharyngeal fistula 1 Asymptomatic N/A
Pharyngeal fistula 2 Symptomatic, invasive inteN/A
Pharyngeal fistula 3 Invasive intervention indi N/A
Pharyngeal fistula 4 Life-threatening consequen N/A
Pharyngeal fistula 5 Death N/A
Pharyngeal fistula Definition A disorder characterized N/A
Pharyngeal hemorrhage 1 Mild symptoms; interventiN/A
Pharyngeal hemorrhage 2 Moderate symptoms; interN/A
Pharyngeal hemorrhage 3 Transfusion indicated; invaN/A
Pharyngeal hemorrhage 4 Life-threatening consequen N/A
Pharyngeal hemorrhage 5 Death N/A
Pharyngeal hemorrhage Definition A disorder characterized bN/A
Pharyngeal mucositis 1 Endoscopic findings only; N/A
Pharyngeal mucositis 2 Moderate pain, analgesicsN/A
Pharyngeal mucositis 3 Severe pain; unable to adeq N/A
Pharyngeal mucositis 4 Life-threatening consequen N/A
Pharyngeal mucositis 5 Death N/A
Pharyngeal mucositis Definition A disorder characterized N/A
Pharyngeal necrosis 3 Inability to aliment adequaN/A
Pharyngeal necrosis 4 Life-threatening consequen N/A
Pharyngeal necrosis 5 Death N/A
Pharyngeal necrosis Definition A disorder characterized bN/A
Pharyngeal stenosis 1 Asymptomatic; clinical or N/A
Pharyngeal stenosis 2 Symptomatic (e.g., noisy aiN/A
Pharyngeal stenosis 3 Limiting self care ADL; stri N/A
Pharyngeal stenosis 4 Life-threatening airway coN/A
Pharyngeal stenosis 5 Death N/A
Pharyngeal stenosis Definition A disorder characterized bN/A
Pharyngolaryngeal pain 1 Mild pain N/A
Pharyngolaryngeal pain 2 Moderate pain; limiting i N/A
Pharyngolaryngeal pain 3 Severe pain; limiting self N/A
Pharyngolaryngeal pain Definition A disorder characterized bN/A
Pleural effusion 1 Asymptomatic; clinical or N/A
Pleural effusion 2 Symptomatic; interventionN/A
Pleural effusion 3 Symptomatic with respirato N/A
Pleural effusion 4 Life-threatening respirat N/A
Pleural effusion 5 Death N/A
Pleural effusion Definition A disorder characterized bN/A
Pleural hemorrhage 1 Asymptomatic; mild hemorN/A
Pleural hemorrhage 2 Symptomatic or associatedN/A
Pleural hemorrhage 3 >1000 ml of blood evacuatedN/A
Pleural hemorrhage 4 Life-threatening consequen N/A
Pleural hemorrhage 5 Death N/A
Pleural hemorrhage Definition A disorder characterized bN/A
Pleuritic pain 1 Mild pain N/A
Pleuritic pain 2 Moderate pain; limiting i N/A
Pleuritic pain 3 Severe pain; limiting self N/A
Pleuritic pain Definition A disorder characterized bN/A
Pneumonitis 1 Asymptomatic; clinical or N/A
Pneumonitis 2 Symptomatic; medical inter N/A
Pneumonitis 3 Severe symptoms; limitingN/A
Pneumonitis 4 Life-threatening respirato N/A
Pneumonitis 5 Death N/A
Pneumonitis Definition A disorder characterized bN/A
Pneumothorax 1 Asymptomatic; clinical or N/A
Pneumothorax 2 Symptomatic; interventionN/A
Pneumothorax 3 Sclerosis and/or operativeN/A
Pneumothorax 4 Life-threatening consequen N/A
Pneumothorax 5 Death N/A
Pneumothorax Definition A disorder characterized byN/A
Postnasal drip 1 Mild symptoms; interventiN/A
Postnasal drip 2 Moderate symptoms; medic N/A
Postnasal drip Definition A disorder characterized bN/A
Productive cough 1 Occasional/minimal produN/A
Productive cough 2 Moderate sputum productio N/A
Productive cough 3 Persistent or copious prodN/A
Productive cough Definition A disorder characterized N/A
Pulmonary edema 1 Radiologic findings only; N/A
Pulmonary edema 2 Moderate dyspnea on exert N/A
Pulmonary edema 3 Severe dyspnea or dyspnea N/A
Pulmonary edema 4 Life-threatening respirato N/A
Pulmonary edema 5 Death N/A
Pulmonary edema Definition A disorder characterized byN/A
Pulmonary fibrosis 1 Radiologic pulmonary fibr N/A
Pulmonary fibrosis 2 Evidence of pulmonary hypN/A
Pulmonary fibrosis 3 Severe hypoxia; evidence oN/A
Pulmonary fibrosis 4 Life-threatening consequeN/A
Pulmonary fibrosis 5 Death N/A
Pulmonary fibrosis Definition A disorder characterized byN/A
Pulmonary fistula 1 Asymptomatic N/A
Pulmonary fistula 2 Symptomatic, invasive inteN/A
Pulmonary fistula 3 Invasive intervention indi N/A
Pulmonary fistula 4 Life-threatening consequen N/A
Pulmonary fistula 5 Death N/A
Pulmonary fistula Definition A disorder characterized N/A
Pulmonary hypertension 1 Minimal dyspnea; findingsN/A
Pulmonary hypertension 2 Moderate dyspnea, cough;N/A
Pulmonary hypertension 3 Severe symptoms, associate N/A
Pulmonary hypertension 4 Life-threatening airway coN/A
Pulmonary hypertension 5 Death N/A
Pulmonary hypertension Definition A disorder characterized bN/A
Respiratory failure 4 Life-threatening consequen N/A
Respiratory failure 5 Death N/A
Respiratory failure Definition A disorder characterized bN/A
Respiratory, thoracic and m
5 Death N/A
Retinoic acid syndrome 1 Fluid retention; <3 kg of wN/A
Retinoic acid syndrome 2 Moderate signs or symptom N/A
Retinoic acid syndrome 3 Severe symptoms; hospitalN/A
Retinoic acid syndrome 4 Life-threatening consequen N/A
Retinoic acid syndrome 5 Death N/A
Retinoic acid syndrome Definition A disorder characterized by N/A
Sinus disorder 1 Asymptomatic mucosal crus N/A
Sinus disorder 2 Symptomatic stenosis or eN/A
Sinus disorder 3 Stenosis with significant nN/A
Sinus disorder 4 Necrosis of soft tissue or N/A
Sinus disorder 5 Death N/A
Sinus disorder Definition A disorder characterized bN/A
Sleep apnea 1 Snoring and nocturnal sle N/A
Sleep apnea 2 Moderate apnea and oxygen N/A
Sleep apnea 3 Oxygen desaturation; assoc N/A
Sleep apnea 4 Cardiovascular or neuropsN/A
Sleep apnea 5 Death N/A
Sleep apnea Definition A disorder characterized bN/A
Sneezing 1 Mild symptoms; interventiN/A
Sneezing 2 Moderate symptoms; medic N/A
Sneezing Definition A disorder characterized bN/A
Sore throat 1 Mild pain N/A
Sore throat 2 Moderate pain; limiting i N/A
Sore throat 3 Severe pain; limiting self cN/A
Sore throat Definition A disorder characterized bN/A
Stridor 3 Respiratory distress limiti N/A
Stridor 4 Life-threatening airway coN/A
Stridor 5 Death N/A
Stridor Definition A disorder characterized bN/A
Tracheal fistula 1 Asymptomatic N/A
Tracheal fistula 2 Symptomatic, invasive inteN/A
Tracheal fistula 3 Invasive intervention indi N/A
Tracheal fistula 4 Life-threatening consequen N/A
Tracheal fistula 5 Death N/A
Tracheal fistula Definition A disorder characterized N/A
Tracheal mucositis 1 Endoscopic findings only; N/A
Tracheal mucositis 2 Moderate symptoms; medica N/A
Tracheal mucositis 3 Severe pain; hemorrhage or N/A
Tracheal mucositis 4 Life-threatening consequen N/A
Tracheal mucositis 5 Death N/A
Tracheal mucositis Definition A disorder characterized N/A
Tracheal stenosis 1 Asymptomatic; clinical or N/A
Tracheal stenosis 2 Symptomatic (e.g., noisy aiN/A
Tracheal stenosis 3 Stridor or respiratory distrN/A
Tracheal stenosis 4 Life-threatening airway coN/A
Tracheal stenosis 5 Death N/A
Tracheal stenosis Definition A disorder characterized bN/A
Voice alteration 1 Mild or intermittent chan N/A
Voice alteration 2 Moderate or persistent chN/A
Voice alteration 3 Severe voice changes incluN/A
Voice alteration Definition A disorder characterized bN/A
Wheezing 1 Detectable airway noise N/A
Wheezing 2 Moderate symptoms; medica N/A
Wheezing 3 Severe respiratory symptom N/A
Wheezing 4 Life-threatening consequen N/A
Wheezing 5 Death N/A
Wheezing Definition A disorder characterized bN/A
Alopecia 1 Hair loss of <50% of normal N/A
Alopecia 2 Hair loss of >=50% normalN/Af
Alopecia Definition A disorder characterized bN/A
Body odor 1 Mild odor; physician intervN/A
Body odor 2 Pronounced odor; psychoso N/A
Body odor Definition A disorder characterized bN/A
Bullous dermatitis 1 Asymptomatic; blisters co N/A
Bullous dermatitis 2 Blisters covering 10 - 30% N/A
Bullous dermatitis 3 Blisters covering >30% BSA; N/A
Bullous dermatitis 4 Blisters covering >30% BSA; N/A
Bullous dermatitis 5 Death N/A
Bullous dermatitis Definition A disorder characterized by N/A
Dry skin 1 Covering <10% BSA and noN/A
Dry skin 2 Covering 10 - 30% BSA andN/A
Dry skin 3 Covering >30% BSA and asso N/A
Dry skin Definition A disorder characterized by N/A
Erythema multiforme 1 Target lesions covering < N/A
Erythema multiforme 2 Target lesions covering 10N/A
Erythema multiforme 3 Target lesions covering >3N/A
Erythema multiforme 4 Target lesions covering >3N/A
Erythema multiforme 5 Death N/A
Erythema multiforme Definition A disorder characterized byN/A
Erythroderma 2 Erythema covering >90% BS N/A
Erythroderma 3 Erythema covering >90% BSA N/A
Erythroderma 4 Erythema covering >90% BSA N/A
Erythroderma 5 Death N/A
Erythroderma Definition A disorder characterized bN/A
Fat atrophy 1 Covering <10% BSA and a N/A
Fat atrophy 2 Covering 10 - 30% BSA andN/A
Fat atrophy 3 Covering >30% BSA; associN/A
Fat atrophy Definition A disorder characterized byN/A
Hirsutism 1 In women, increase in lengtN/A
Hirsutism 2 In women, increase in lengN/A
Hirsutism Definition A disorder characterized N/A
Hyperhidrosis 1 Limited to one site (palms,N/A
Hyperhidrosis 2 Involving >1 site; patient N/A
Hyperhidrosis 3 Associated with electrol N/A
Hyperhidrosis Definition A disorder characterized bN/A
Hypertrichosis 1 Increase in length, thickn N/A
Hypertrichosis 2 Increase in length, thickn N/A
Hypertrichosis Definition A disorder characterized byN/A
Hypohidrosis 2 Symptomatic; limiting ins N/A
Hypohidrosis 3 Increase in body temperatu N/A
Hypohidrosis 4 Heat stroke N/A
Hypohidrosis 5 Death N/A
Hypohidrosis Definition A disorder characterized N/A
Lipohypertrophy 1 Asymptomatic and coveri N/A
Lipohypertrophy 2 Covering 10 - 30% BSA andN/A
Lipohypertrophy 3 Covering >30% BSA and asso N/A
Lipohypertrophy Definition A disorder characterized bN/A
Nail discoloration 1 Asymptomatic; clinical or N/A
Nail discoloration Definition A disorder characterized byN/A
Nail loss 1 Asymptomatic separation N/Aof
Nail loss 2 Symptomatic separation ofN/At
Nail loss Definition A disorder characterized byN/A
Nail ridging 1 Asymptomatic; clinical or N/A
Nail ridging Definition A disorder characterized byN/A
Pain of skin 1 Mild pain N/A
Pain of skin 2 Moderate pain; limiting i N/A
Pain of skin 3 Severe pain; limiting self N/A
Pain of skin Definition A disorder characterized bN/A
Palmar-plantar erythrody 1 Minimal skin changes or deN/A
Palmar-plantar erythrody 2 Skin changes (e.g., peelingN/A
Palmar-plantar erythrody 3 Severe skin changes (e.g., N/A
Palmar-plantar erythrody Definition A disorder characterized bN/A
Periorbital edema 1 Soft or non-pitting N/A
Periorbital edema 2 Indurated or pitting edemaN/A
Periorbital edema 3 Edema associated with visu N/A
Periorbital edema Definition A disorder characterized bN/A
Photosensitivity 1 Painless erythema and er N/A
Photosensitivity 2 Tender erythema coveringN/A
Photosensitivity 3 Erythema covering >30% BSA N/A
Photosensitivity 4 Life-threatening consequen N/A
Photosensitivity 5 Death N/A
Photosensitivity Definition A disorder characterized byN/A
Pruritus 1 Mild or localized; topical N/A
Pruritus 2 Widespread and intermitten N/A
Pruritus 3 Widespread and constant;N/A l
Pruritus Definition A disorder characterized bN/A
Purpura 1 Combined area of lesions N/A
Purpura Definition A disorder characterized bN/A
Rash acneiform 1 Papules and/or pustules c N/A
Rash acneiform 2 Papules and/or pustules c N/A
Rash acneiform 3 Papules and/or pustules coN/A
Rash acneiform 4 Life-threatening consequen N/A
Rash acneiform 5 Death N/A
Rash acneiform Definition A disorder characterized bN/A
Rash maculo-papular 1 Macules/papules coveringN/A
Rash maculo-papular 2 Macules/papules coveringN/A1
Rash maculo-papular 3 Macules/papules coveringN/A
Rash maculo-papular Definition A disorder characterized bN/A
Scalp pain 1 Mild pain N/A
Scalp pain 2 Moderate pain; limiting i N/A
Scalp pain 3 Severe pain; limiting self N/A
Scalp pain Definition A disorder characterized bN/A
Skin and subcutaneous tiss1 Asymptomatic or mild sympt N/A
Skin and subcutaneous tiss2 Moderate; minimal, local oN/A
Skin and subcutaneous tiss3 Severe or medically signifiN/A
Skin and subcutaneous tiss4 Life-threatening consequen N/A
Skin and subcutaneous tiss5 Death N/A
Skin atrophy 1 Covering <10% BSA; associa N/A
Skin atrophy 2 Covering 10 - 30% BSA; assN/A
Skin atrophy 3 Covering >30% BSA; associN/A
Skin atrophy Definition A disorder characterized bN/A
Skin hyperpigmentation 1 Hyperpigmentation coveriN/A
Skin hyperpigmentation 2 Hyperpigmentation coveriN/A
Skin hyperpigmentation Definition A disorder characterized bN/A
Skin hypopigmentation 1 Hypopigmentation or depiN/A
Skin hypopigmentation 2 Hypopigmentation or depiN/A
Skin hypopigmentation Definition A disorder characterized by N/A
Skin induration 1 Mild induration, able to mo N/A
Skin induration 2 Moderate induration, ableN/A t
Skin induration 3 Severe induration; unable N/A
t
Skin induration 4 Generalized; associated wN/A
Skin induration 5 Death N/A
Skin induration Definition A disorder characterized bN/A
Skin ulceration 1 Combined area of ulcers <N/A
Skin ulceration 2 Combined area of ulcers 1N/A-
Skin ulceration 3 Combined area of ulcers >2 N/A
Skin ulceration 4 Any size ulcer with extensiN/A
Skin ulceration 5 Death N/A
Skin ulceration Definition A disorder characterized by N/A
Stevens-Johnson syndrom3 Skin sloughing covering N/A
Stevens-Johnson syndrom4 Skin sloughing covering 1 N/A
Stevens-Johnson syndrom5 Death N/A
Stevens-Johnson syndromDefinition A disorder characterized bN/A
Telangiectasia 1 Telangiectasias covering N/A
Telangiectasia 2 Telangiectasias covering N/A
Telangiectasia Definition A disorder characterized bN/A
Toxic epidermal necrolysis4 Skin sloughing covering > N/A
Toxic epidermal necrolysis5 Death N/A
Toxic epidermal necrolysisDefinition A disorder characterized bN/A
Urticaria 1 Urticarial lesions covering N/A
Urticaria 2 Urticarial lesions covering N/A
Urticaria 3 Urticarial lesions coverin N/A
Urticaria Definition A disorder characterized bN/A
Premature menopause Definition A disorder characterized bN/A
Social circumstances - Oth1 Asymptomatic or mild sympt N/A
Social circumstances - Oth2 Moderate; minimal, local oN/A
Social circumstances - Oth3 Severe or medically signifiN/A
Social circumstances - Oth4 Life-threatening consequen N/A
Social circumstances - Oth5 Death N/A
Surgical and medical proce1 Asymptomatic or mild sympt N/A
Surgical and medical proce2 Moderate; minimal, local oN/A
Surgical and medical proce3 Severe or medically signifiN/A
Surgical and medical proce4 Life-threatening consequen N/A
Surgical and medical proce5 Death N/A
Capillary leak syndrome 2 Symptomatic; medical inteN/A
Capillary leak syndrome 3 Severe symptoms; interven N/A
Capillary leak syndrome 4 Life-threatening consequen N/A
Capillary leak syndrome 5 Death N/A
Capillary leak syndrome Definition A disorder characterized bN/A
Flushing 1 Asymptomatic; clinical or N/A
Flushing 2 Moderate symptoms; limitN/A
Flushing 3 Symptomatic, associated wi N/A
Flushing Definition A disorder characterized byN/A
Hematoma 1 Mild symptoms; interventiN/A
Hematoma 2 Minimally invasive evacuatN/A
Hematoma 3 Transfusion; invasive inte N/A
Hematoma 4 Life-threatening consequen N/A
Hematoma 5 Death N/A
Hematoma Definition A disorder characterized byN/A
Hot flashes 1 Mild symptoms; interventiN/A
Hot flashes 2 Moderate symptoms; limitN/A
Hot flashes 3 Severe symptoms; limitingN/A
Hot flashes Definition A disorder characterized N/A
Hypertension 1 Adolescent: BP ≥120/80 evenN/A if < 95th percentile
Hypertension 2 Adolescent: Systolic between
N/A130-139 or diastolic between 80-89 even if < 9
Hypertension 3 Pediatric and adolescent: N/A
Hypertension 4 Adult and Pediatric: Life-threatening
N/A consequences (e.g., malignant hyperte
Hypertension 5 Death N/A
Hypertension Definition A disorder characterized bN/A
Hypotension 1 Asymptomatic, interventioN/A
Hypotension 2 Non-urgent medical intervN/A
Hypotension 3 Medical intervention indicN/A
Hypotension 4 Life-threatening consequeN/A
Hypotension 5 Death N/A
Hypotension Definition A disorder characterized bN/A
Lymph leakage 2 Symptomatic; medical inteN/A
Lymph leakage 3 Severe symptoms; invasiveN/A
Lymph leakage 4 Life-threatening consequen N/A
Lymph leakage 5 Death N/A
Lymph leakage Definition A disorder characterized byN/A
Lymphedema 1 Trace thickening or faint dN/A
Lymphedema 2 Marked discoloration; leatN/A
Lymphedema 3 Severe symptoms; limitingN/A
Lymphedema Definition A disorder characterized byN/A
Lymphocele 1 Asymptomatic; clinical or N/A
Lymphocele 2 Symptomatic; medical inteN/A
Lymphocele 3 Severe symptoms; invasiveN/A
Lymphocele Definition A disorder characterized bN/A
Peripheral ischemia 2 Brief (<24 hrs) episode o N/A
Peripheral ischemia 3 Prolonged (>=24 hrs) or r N/A
Peripheral ischemia 4 Life-threatening consequeN/A
Peripheral ischemia 5 Death N/A
Peripheral ischemia Definition A disorder characterized bN/A
Phlebitis 2 Present N/A
Phlebitis Definition A disorder characterized bN/A
Superficial thrombophlebit2 Present N/A
Superficial thrombophlebitDefinition A disorder characterized byN/A
Superior vena cava syndr 1 Asymptomatic; incidental N/A
Superior vena cava syndr 2 Symptomatic; medical inter N/A
Superior vena cava syndr 3 Severe symptoms; multi-mod N/A
Superior vena cava syndr 4 Life-threatening consequen N/A
Superior vena cava syndr 5 Death N/A
Superior vena cava syndr Definition A disorder characterized bN/A
Thromboembolic event 1 Medical intervention not inN/A
Thromboembolic event 2 Medical intervention indi N/A
Thromboembolic event 3 Urgent medical interventi N/A
Thromboembolic event 4 Life-threatening consequeN/A
Thromboembolic event 5 Death N/A
Thromboembolic event Definition A disorder characterized bN/A
Vascular disorders - Other,1 Asymptomatic or mild sympt N/A
Vascular disorders - Other,2 Moderate; minimal, local oN/A
Vascular disorders - Other,3 Severe or medically signifiN/A
Vascular disorders - Other,4 Life-threatening consequen N/A
Vascular disorders - Other,5 Death N/A
Vasculitis 1 Asymptomatic, interventioN/A
Vasculitis 2 Moderate symptoms, medic N/A
Vasculitis 3 Severe symptoms, medicalN/A i
Vasculitis 4 Life-threatening consequen N/A
Vasculitis 5 Death N/A
Vasculitis Definition A disorder characterized bN/A
Visceral arterial ischemia 2 Brief (<24 hrs) episode o N/A
Visceral arterial ischemia 3 Prolonged (>=24 hrs) or r N/A
Visceral arterial ischemia 4 Life-threatening consequeN/A
Visceral arterial ischemia 5 Death N/A
Visceral arterial ischemia Definition A disorder characterized bN/A
on-White syndrome
on-White syndrome
on-White syndrome
on-White syndrome
on-White syndrome
perforation
sory neuropathy
terior leukoencephalopathy syndrome

l tract fistula
l tract fistula
l tract fistula
l tract fistula
l tract fistula
uscle weakness
uscle weakness

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MedDRA Code MedDRA SOC CTCAE Term Grade 1

dicate an increased number of white blood cells in the blood.

note; Clarification: Grade 2, 3, Definition

note; Clarification: Grade 2, 3

icardial sac, usually due to inflammation.

ponse to irritation), swelling and redness to the middle ear.

hyroid hormone by the thyroid gland.

n occurring in a female or prepubertal male.

mfort in the eye.

igational note; Clarification: Grade 2, 3, 4

mfort in the abdominal region.

note; Clarification: Definition; Deletion: Grade 4, 5

mfort in the anal region.

morrhagic fluid in the peritoneal cavity.

ncomfortable fullness of the abdomen.

note; Clarification: Grade 3

fficult evacuation of the bowels.

e of stool from the rectum.

mfort in the gastrointestinal region.

mfort of the lip.

mfort in the rectal region.

mfort in the stomach.

mfort in the tooth.

marks a physiologic response to sweating after a fever.

d accumulation in facial tissues.

note; Clarification: Definition

of the contents of the gallbladder.

mfort in the liver region.

in the portal venous system.

note; Clarification: Grade 1, 2, 3

igational note; Clarification: Grade 2, 3; Primary SOC change

g the brain tissue.

note; Clarification: Grade 2, 3

note; Clarification: Grade 2, 3, Definition

larification: Grade 3; Deletion Grade 2

note; Clarification: Grade 2, 3

note; Clarification: Grade 3

larification: Grade 3; Deletion Grade 2

larification: Grade 3; Deletion Grade 2

larification: Grade 3; Deletion Grade 2

3, Definition; Deletion: Grade 1

ntinuity of a vertebral bone is broken.

note; Clarification: Grade 1, 2, 3, 4

note; Clarification: Grade 1, 2, 3, 4

note; Clarification: Grade 1, 2, 3, 4

note; Clarification: Grade 1, 2, 3, 4

bnormal levels of prolactin hormone in a blood specimen.

bnormal levels of growth hormone in a biological specimen.

decrease in number of lymphocytes in a blood specimen.

note; Clarification: Definition

dicate an elevation in the concentration of magnesium in the blood.

dicate an elevation in the concentration of triglyceride concentration in the blood.

dicate a low concentration of albumin in the blood.

result from a spontaneous or therapy-related cytolysis of tumor cells.

ervical spine joint.

originating from a muscle or group of muscles.

n the bone of the mandible.

f the mutagenic effect of chemotherapy agents.