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    Drug Study - Paracetamol

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    Carla Tongson Maravilla
    Paracetamol (acetaminophen) is a nonopioid analgesic and antipyretic drug. It works by inhibiting prostaglandin synthesis in the central nervous system, primarily reducing pain and fever. The drug is commonly used to treat mild to moderate pain and fever. It has dosages of 300 mg every 8 hours by mouth or IV. Contraindications include hypersensitivity, liver impairment, and excessive alcohol use. Adverse effects include central nervous system issues like agitation, anxiety, and headache. Nurses monitor patients' health status, drug usage, and signs of toxicity like abnormal liver enzymes when using this drug long-term or in high doses.

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    Drug Study - Paracetamol

    Uploaded by

    Carla Tongson Maravilla
    9K views2 pages
    Paracetamol (acetaminophen) is a nonopioid analgesic and antipyretic drug. It works by inhibiting prostaglandin synthesis in the central nervous system, primarily reducing pain and fever. The drug is commonly used to treat mild to moderate pain and fever. It has dosages of 300 mg every 8 hours by mouth or IV. Contraindications include hypersensitivity, liver impairment, and excessive alcohol use. Adverse effects include central nervous system issues like agitation, anxiety, and headache. Nurses monitor patients' health status, drug usage, and signs of toxicity like abnormal liver enzymes when using this drug long-term or in high doses.

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    Paracetamol (acetaminophen) is a nonopioid analgesic and antipyretic drug. It works by inhibiting prostaglandin synthesis in the central nervous system, primarily reducing pain and fever. The drug is commonly used to treat mild to moderate pain and fever. It has dosages of 300 mg every 8 hours by mouth or IV. Contraindications include hypersensitivity, liver impairment, and excessive alcohol use. Adverse effects include central nervous system issues like agitation, anxiety, and headache. Nurses monitor patients' health status, drug usage, and signs of toxicity like abnormal liver enzymes when using this drug long-term or in high doses.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    9K views2 pages

    Drug Study - Paracetamol

    Uploaded by

    Carla Tongson Maravilla
    Paracetamol (acetaminophen) is a nonopioid analgesic and antipyretic drug. It works by inhibiting prostaglandin synthesis in the central nervous system, primarily reducing pain and fever. The drug is commonly used to treat mild to moderate pain and fever. It has dosages of 300 mg every 8 hours by mouth or IV. Contraindications include hypersensitivity, liver impairment, and excessive alcohol use. Adverse effects include central nervous system issues like agitation, anxiety, and headache. Nurses monitor patients' health status, drug usage, and signs of toxicity like abnormal liver enzymes when using this drug long-term or in high doses.

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    © All Rights Reserved
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    Drug Study Paracetamol

    Name of Drug Dosage, Mechanism of Indication Contraindication Adverse Effect Nursing Responsibility
    Route and Action
    Frequency

    Generic Name: Dosage: Inhibits the PO, Rect: Contraindicated in: CNS: agitation (in Interventions:
    synthesis of Treatment of: Mild Previous children) (IV), anxiety ● Assess overall health status and alcohol usage before
    Paracetamol / 300
    prostaglandins pain, Fever. IV hypersensitivity; (IV), headache (IV), administering acetaminophen. Patients who are malnourished or
    Acetaminophen mg/amp, 2
    that may serve Treatment of: Mild Products containing fatigue (IV), insomnia chronically abuse alcohol are at higher risk of developing
    ampules
    Brand Name: as mediators of to moderate pain, alcohol, aspartame, (IV). hepatotoxicity with chronic use of usual doses of this drug.
    pain and fever, Moderate to severe saccharin, sugar, or
    Abenol, Acephen, Acet, primarily in the pain with opioid tartrazine (FDC
    ● Assess amount, frequency, and type of drugs taken in patients
    APAP, Artritol, Aspirin Frequency CNS. Has no self-medicating, especially with OTC drugs. Prolonged use of
    analgesics, Fever. yellow dye #5)
    Free Anacin, Atasol, acetaminophen increases the risk of adverse renal effects. For short-
    Q8hrs x 6 significant anti- should be avoided in term use, combined doses of acetaminophen and salicylates should
    Cetafen, Feverall, inflammatory patients who have
    doses not exceed the recommended dose of either drug given alone. Do
    Fortolin, Infantaire, properties or GI hypersensitivity or not exceed maximum daily dose of acetaminophen when
    Little Fevers, Mapap, toxicity. intolerance to these considering all routes of administration and all combination
    Nortemp Children’s, compounds; Severe products containing acetaminophen.
    Ofirmev, Pain-Eze, Route:
    hepatic
    Pediaphen, Pediatrix, IVTT ● Pain: Assess type, location, and intensity prior to and 30– 60 min
    impairment/active following administration.
    Silapap , Silapap liver disease.
    Infant’s, Taminol, ● Fever: Assess fever; note presence of associated signs
    Tempra, Tylenol, (diaphoresis, tachycardia, and malaise).
    Valorin
    ● Lab Test Considerations: Evaluate hepatic, hematologic, and renal
    Classification: function periodically during prolonged, high-dose therapy.

    Antipyretics, Nonopioid ● May alter results of blood glucose monitoring. May cause
    Analgesics falselypvalues when measured with glucose oxidase/peroxidase
    method, but probably not with hexokinase/G6PD method. May also
    cause falselyqvalues with certain instruments; see manufacturer’s
    instruction manual.
    ● Increased serum bilirubin, LDH, AST, ALT, and prothrombin
    time may indicate hepatotoxicity.
    ● Toxicity and Overdose: If overdose occurs, acetylcysteine
    (Acetadote) is the antidote.

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